CN114748387B - Whitening and skin-moistening emulsion - Google Patents
Whitening and skin-moistening emulsion Download PDFInfo
- Publication number
- CN114748387B CN114748387B CN202210436218.6A CN202210436218A CN114748387B CN 114748387 B CN114748387 B CN 114748387B CN 202210436218 A CN202210436218 A CN 202210436218A CN 114748387 B CN114748387 B CN 114748387B
- Authority
- CN
- China
- Prior art keywords
- acid
- fruit
- butter
- rhodiola rosea
- whitening
- Prior art date
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- 230000002087 whitening effect Effects 0.000 title claims abstract description 44
- 239000000839 emulsion Substances 0.000 title claims abstract description 36
- 244000042430 Rhodiola rosea Species 0.000 claims abstract description 46
- 235000003713 Rhodiola rosea Nutrition 0.000 claims abstract description 46
- 239000000284 extract Substances 0.000 claims abstract description 40
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 27
- 239000002253 acid Substances 0.000 claims abstract description 24
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims abstract description 20
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims abstract description 13
- 240000000902 Diospyros discolor Species 0.000 claims abstract description 11
- 235000003115 Diospyros discolor Nutrition 0.000 claims abstract description 11
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 9
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims abstract description 8
- 235000012208 gluconic acid Nutrition 0.000 claims abstract description 8
- 239000000174 gluconic acid Substances 0.000 claims abstract description 8
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims abstract description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims abstract description 3
- 235000015165 citric acid Nutrition 0.000 claims abstract description 3
- 235000011090 malic acid Nutrition 0.000 claims abstract description 3
- 239000001630 malic acid Substances 0.000 claims abstract description 3
- BXWNKGSJHAJOGX-UHFFFAOYSA-N n-hexadecyl alcohol Natural products CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 47
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 claims description 36
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 34
- 229920001285 xanthan gum Polymers 0.000 claims description 28
- 229940082509 xanthan gum Drugs 0.000 claims description 28
- 235000010493 xanthan gum Nutrition 0.000 claims description 28
- 239000000230 xanthan gum Substances 0.000 claims description 28
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 230000003020 moisturizing effect Effects 0.000 claims description 22
- 229960000541 cetyl alcohol Drugs 0.000 claims description 21
- 239000008213 purified water Substances 0.000 claims description 21
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 claims description 18
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 claims description 18
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 claims description 18
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 claims description 18
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims description 18
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims description 17
- 235000019437 butane-1,3-diol Nutrition 0.000 claims description 17
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 claims description 17
- -1 polyoxyethylene Polymers 0.000 claims description 17
- 229940083037 simethicone Drugs 0.000 claims description 17
- 238000003756 stirring Methods 0.000 claims description 17
- FCGXLCNBWYIEAA-UHFFFAOYSA-N 1,3-benzothiazol-6-ylmethanamine Chemical compound NCC1=CC=C2N=CSC2=C1 FCGXLCNBWYIEAA-UHFFFAOYSA-N 0.000 claims description 16
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 13
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 13
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 13
- 235000014121 butter Nutrition 0.000 claims description 13
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 11
- MEJYDZQQVZJMPP-ULAWRXDQSA-N (3s,3ar,6r,6ar)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan Chemical compound CO[C@H]1CO[C@@H]2[C@H](OC)CO[C@@H]21 MEJYDZQQVZJMPP-ULAWRXDQSA-N 0.000 claims description 10
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims description 8
- 235000000857 Pentadesma butyracea Nutrition 0.000 claims description 7
- 240000002134 Pentadesma butyracea Species 0.000 claims description 7
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims description 6
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 5
- KLDXJTOLSGUMSJ-JGWLITMVSA-N Isosorbide Chemical compound O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@@H]21 KLDXJTOLSGUMSJ-JGWLITMVSA-N 0.000 claims description 4
- HHLFWLYXYJOTON-UHFFFAOYSA-N glyoxylic acid Chemical compound OC(=O)C=O HHLFWLYXYJOTON-UHFFFAOYSA-N 0.000 claims description 4
- 229960002479 isosorbide Drugs 0.000 claims description 4
- 244000025272 Persea americana Species 0.000 claims description 3
- 235000008673 Persea americana Nutrition 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 229940012831 stearyl alcohol Drugs 0.000 claims description 2
- UBHWBODXJBSFLH-UHFFFAOYSA-N hexadecan-1-ol;octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO.CCCCCCCCCCCCCCCCCCO UBHWBODXJBSFLH-UHFFFAOYSA-N 0.000 claims 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 229920002545 silicone oil Polymers 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 abstract description 7
- 239000006210 lotion Substances 0.000 abstract description 3
- 239000000047 product Substances 0.000 description 36
- 230000000052 comparative effect Effects 0.000 description 28
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- 230000000694 effects Effects 0.000 description 17
- 230000005764 inhibitory process Effects 0.000 description 12
- 238000002360 preparation method Methods 0.000 description 12
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 11
- 229940057910 shea butter Drugs 0.000 description 9
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 8
- 235000005152 nicotinamide Nutrition 0.000 description 8
- 239000011570 nicotinamide Substances 0.000 description 8
- 229960003966 nicotinamide Drugs 0.000 description 8
- 239000000243 solution Substances 0.000 description 6
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 description 5
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 description 5
- 239000007853 buffer solution Substances 0.000 description 5
- 206010013786 Dry skin Diseases 0.000 description 4
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- 238000002835 absorbance Methods 0.000 description 4
- 229960000271 arbutin Drugs 0.000 description 4
- 230000037336 dry skin Effects 0.000 description 4
- BJRNKVDFDLYUGJ-UHFFFAOYSA-N p-hydroxyphenyl beta-D-alloside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-UHFFFAOYSA-N 0.000 description 4
- 230000001815 facial effect Effects 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 description 3
- 229960004705 kojic acid Drugs 0.000 description 3
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 229940058015 1,3-butylene glycol Drugs 0.000 description 2
- YCCILVSKPBXVIP-UHFFFAOYSA-N 2-(4-hydroxyphenyl)ethanol Chemical compound OCCC1=CC=C(O)C=C1 YCCILVSKPBXVIP-UHFFFAOYSA-N 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
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- 239000002884 skin cream Substances 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 description 1
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 description 1
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- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- DBLDQZASZZMNSL-QMMMGPOBSA-N L-tyrosinol Natural products OC[C@@H](N)CC1=CC=C(O)C=C1 DBLDQZASZZMNSL-QMMMGPOBSA-N 0.000 description 1
- 208000003351 Melanosis Diseases 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- ILRCGYURZSFMEG-UHFFFAOYSA-N Salidroside Natural products OC1C(O)C(O)C(CO)OC1OCCC1=CC=C(O)C=C1 ILRCGYURZSFMEG-UHFFFAOYSA-N 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
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- 108091000117 Tyrosine 3-Monooxygenase Proteins 0.000 description 1
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- 230000002378 acidificating effect Effects 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 1
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- 230000008859 change Effects 0.000 description 1
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- 239000004519 grease Substances 0.000 description 1
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
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- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000008099 melanin synthesis Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
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- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- ILRCGYURZSFMEG-RQICVUQASA-N salidroside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1OCCC1=CC=C(O)C=C1 ILRCGYURZSFMEG-RQICVUQASA-N 0.000 description 1
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- 235000004330 tyrosol Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to rhodiola rosea whitening and skin-moistening emulsion, and belongs to the technical field of cosmetics. The whitening and skin-moistening emulsion contains butter fruit oil, rhodiola rosea extract and fruit acid, wherein the feeding mass ratio of the butter fruit oil to the rhodiola rosea extract to the fruit acid is 2.2-4:3-8:1-3. The fruit acid is one or more selected from glycolic acid, citric acid, malic acid and gluconic acid, preferably glycolic acid and gluconic acid. The invention provides a skin lotion containing rhodiola rosea, which has good fluidity, is easy to apply on skin, has good extensibility, is fresh and not greasy, is comfortable and smooth after being used, and is suitable for being used in all seasons.
Description
Technical Field
The invention relates to rhodiola rosea whitening and skin-moistening emulsion, and belongs to the technical field of cosmetics.
Background
The dryness of the skin is caused by lack of water, so that the supplement of water and nutrition to the skin is a major function of cosmetics.
The skin-moistening emulsion is an emulsion, can quickly moisten skin, supplements moisture for dry skin, has good fluidity, and has good comfort compared with a face cream product, and the skin surface is fresh and has no thick sense after use. The emulsion has high moisture content, and can form a thin and breathable protective film on the skin surface to prevent moisture loss and achieve the moisturizing effect. The skin lotion and the skin cream belong to basic skin care, are required to be used all the year round, and can be generally used whether the skin is dry skin without water or skin without grease.
The skin-moistening emulsion can deeply moisten dry skin, contains more nutrient components, can reconstruct oily substances washed off the skin into a protective layer, can supplement water required by the skin, and is one of skin-care products commonly used in daily life of people loving beauty. The skin-moistening emulsion has different performances and functions due to different raw materials and formulas. Various skin lotions are commercially available to substantially meet the needs of moisturizing the skin. With the improvement of living standard, the requirements of people on the skin-moistening emulsion are not only remained on the skin, but also the functions of whitening, freckle removing and the like are gradually added into the skin-moistening emulsion.
Under the age of 'economical value', the market scale of skin care products is expanded year by year, and especially, the whitening cosmetics are popular in China and even Asia. Today, anti-aging and whitening have become the main complaints of female populations, even with a trend to exceed the need for moisturizing. In recent years, some whitening products for removing the horny layer are presented, and common whitening additives are: arbutin, kojic acid, nicotinamide or V C. The arbutin is unstable under the acidic condition and is easy to hydrolyze, and meanwhile, the light stability of the arbutin is poor, so that the use effect of the cosmetics added with the additive is limited; kojic acid is another common whitening component, the standard addition concentration is generally between 0.1% and 1%, and is not suitable for sensitive skin, dry skin and oily skin also need to be established from low concentration to be tolerant, in a word, arbutin and kojic acid pregnant women are not suitable for long-term use and are also not suitable for sensitive skin; vc is unstable in light and is easy to sense light, and allergy is also easy to cause when a VC-containing whitening product is used, and the user should try at the positions such as behind the ear to check whether the user is allergic or not; niacinamide contains niacin, so that there is a tolerance problem, and usually the optimal use concentration of niacinamide is between 1% and 5%, and it should be noted that although niacinamide has a better whitening effect, the tolerance degree of each person to niacinamide is different, and the concentration of niacinamide in the whitening product is generally not more than 5%. The higher the nicotinamide concentration, the greater the skin irritation and the increased the allergy probability. Therefore, it is not suggested to use whitening products having higher concentrations of nicotinamide for a long period of time.
In conclusion, the existing whitening products have poor stability and are easy to cause skin allergy and other symptoms when frequently used. Therefore, the provision of a safe and effective whitening and moisturizing cosmetic is a matter of consistent search by cosmetic developers.
Disclosure of Invention
The invention aims to: solves the problems existing in the prior art and provides safe and effective whitening and skin-moistening emulsion.
The technical scheme is as follows:
The rhodiola rosea extract is an extract of rhodiola rosea root, has fragrant and sweet smell and bitter taste, and the main components of the rhodiola rosea extract are salidroside and aglycone tyrosol, and have the effects of enhancing immunity, protecting cardiovascular and cerebrovascular diseases, resisting cancer and depression, preventing tumors, enhancing immunity, delaying aging, resisting fatigue, resisting anoxia, protecting radiation, bidirectionally regulating central nerves and the like.
The applicant finds that the rhodiola rosea extract is used in the skin-moistening emulsion and has a certain whitening function, and particularly, the rhodiola rosea extract is reasonably matched with fruit acid and butter oil of the butter tree, so that a very good whitening effect is achieved.
The technical scheme of the invention is as follows:
A whitening and skin-moistening emulsion comprises butter oil, radix Rhodiolae extract and fruit acid, wherein the mass ratio of butter oil, radix Rhodiolae extract and fruit acid is 2.2-4:3-8:1-3, preferably 2.8-3.5:5-7:1.5-2.5; further preferred is 3.2:6:2.
The fruit acid is one or more selected from glycolic acid, citric acid, malic acid and gluconic acid, preferably glycolic acid and gluconic acid.
Preferably, the whitening and moisturizing emulsion contains 1-2.5% of polyoxyethylene cetyl alcohol ether, 1-2% of monoglyceride, 1-2% of hexadecyl/stearyl alcohol, 1-2% of simethicone, 3-6% of isohexadecane, 4-6% of caprylic triglyceride, 0.1-0.2% of 1,3 butanediol, 3-5% of sodium pyrrolidone carboxylate, butter fruit oil of a butter tree, rhodiola rosea extract and fruit acid, 2.8-3.5% of isosorbide dimethyl ether and xanthan gum, wherein the mass ratio of the butter fruit oil of the butter fruit tree, the rhodiola rosea extract and the fruit acid is 2.2-4:3-8:1-3, 1-1.9% of dimethyl isosorbide ether is 1.5-2.5 times of the xanthan gum, and the balance is purified water.
Preferably, the whitening and moisturizing emulsion contains 1.4-2% of polyoxyethylene cetyl alcohol ether, 1.3-1.8% of monoglyceride, 1.4-1.8% of hexadecyl/stearyl alcohol, 1.4-1.7% of simethicone, 4-5% of isohexadecane, 4.5-5.5% of caprylic acid triglyceride and 1,3
0.1-0.2% Of butanediol, 3.5-4.5% of sodium pyrrolidone carboxylate, 2.8-3.5% of avocado fruit resin oil, 2.8-3.5% of rhodiola rosea extract and fruit acid, 1.5-7:1.5-2.5% of avocado fruit resin oil, 1.3-1.7% of isosorbide dimethyl ether, 1.8-2.2 times of xanthan gum and the balance of purified water.
Preferably, the whitening and moisturizing emulsion contains 1.8% of polyoxyethylene cetyl alcohol ether, 1.6% of monoglyceride, 1.5% of hexadecyl/stearyl alcohol, 1.5% of simethicone, 4.0% of isohexadecane, 5.0% of caprylic triglyceride, 0.15% of 1,3 butanediol, 4.0% of sodium pyrrolidone carboxylate, 3.2% of butter oil of butter tree, rhodiola rosea extract and fruit acid, 3.2% of dimethyl isosorbide and xanthan gum, wherein the feeding mass ratio of the butter oil of butter tree, the rhodiola rosea extract and the glycollic acid is 3.2:6:2, 1.5% of dimethyl isosorbide is 2 times of xanthan gum, and the balance is purified water.
The percentages are mass percentages.
In the technical scheme of the invention, the dosage of the xanthan gum in 1000g of the product is not more than 7.5g, otherwise, the product has poor ductility.
According to the whitening and skin-moistening emulsion disclosed by the invention, the butter oil of the butter tree (BUTYROSPERMUM PARKII) in the formula can increase the stability of the rhodiola rosea extract, and the rhodiola rosea extract and the fruit acid can increase the whitening effect.
The preparation method of the whitening and moisturizing emulsion comprises the following steps:
Step 1, uniformly mixing monoglyceride, hexadecyl/stearyl alcohol, simethicone, isohexadecane, caprylic acid triglyceride, 1,3 butanediol, sodium pyrrolidone carboxylate, isosorbide dimethyl ether and fruit acid according to the formula amount;
step2, adding the formula amount of polyoxyethylene cetyl alcohol ether and isosorbide dimethyl ether into two-thirds formula amount of purified water under stirring, and stirring for dissolution;
Step 3, adding the xanthan gum with the formula amount into one third of purified water with the formula amount under stirring, heating to 50 ℃, stirring and dissolving, and cooling to room temperature;
step 4, uniformly mixing the formula amount of the butter oil of the Butyrospermum parkii and the formula amount of the rhodiola rosea extract;
Step 5, uniformly mixing the solutions obtained in the step 2 and the step 3 at room temperature; slowly adding the mixture into the mixture obtained in the step 1 under stirring;
and 6, adding the mixture obtained in the step 4 into the mixture obtained in the step 5 under stirring at room temperature to obtain the whitening and moisturizing emulsion.
According to the preparation method, the rhodiola rosea extract is firstly mixed with the butter oil of the butter tree (BUTYROSPERMUM PARKII) with the formula amount uniformly, and then the mixture obtained in the step 5 is mixed uniformly, so that the rhodiola rosea can be protected from being oxidized, and the preservation time of the obtained whitening skin-moistening emulsion can be prolonged.
According to the technical scheme, the addition of the xanthan gum and the isosorbide dimethyl ether solves the problem that the skin cream is easy to delaminate in the storage process, and the effect is best when the mass ratio of the isosorbide dimethyl ether to the xanthan gum is 1.5-2.5:1, so that the storage time can be prolonged well.
The beneficial effects are that:
Tyrosinase has various characteristic catalytic activities, can be used as tyrosine hydroxylase and dopa oxidase, and can also be used as 5, 6-dihydroxyindole oxidase, and plays a vital role in the melanin generation process. The tyrosinase activity is high, namely melanin production of the product is increased when the tyrosinase acts with tyrosine, and various black spots are generated on the facial skin.
According to the rhodiola rosea whitening and moisturizing emulsion, through reasonable compatibility of plant extract components, the catalytic activity of tyrosinase can be well inhibited, the formation of melanin is prevented, and the rhodiola rosea whitening and moisturizing emulsion has a certain whitening effect while moisturizing skin.
The rhodiola rosea whitening skin-moistening emulsion disclosed by the invention has excellent fluidity and ductility, is easy to apply on skin, is fresh and cool, is not greasy, is comfortable and smooth after being used, and is suitable for being used in all seasons.
After the skin-moistening emulsion is used, the skin-moistening emulsion has the effects of whitening, resisting oxidation, resisting aging and the like. The facial mask has the functions of moistening and protecting skin, can prevent sunburn and resist cold wind invasion, has excellent moisturizing function, can enhance skin immunity, gives moderate elasticity to the skin, and ensures that the facial skin contains water moderately, is fine, smooth, bright and flat.
Detailed Description
The embodiment of the invention uses the rhodiola rosea glycoside extract as the rhodiola rosea extract produced by the applicant, wherein the content of the rhodiola rosea glycoside is 2.86%.
Example 1. Polyoxyethylene cetyl ether 10g, monoglyceride 20g, stearyl alcohol 10g, simethicone 20g, isohexadecane 30g, caprylic triglyceride 60g,1,3 butylene glycol 1g, sodium pyrrolidone carboxylate 50g, dimethyl ether isosorbide 10g, xanthan gum 6.7g, shea butter 22g, rhodiola rosea extract 30g, gluconic acid 30g, and the balance purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Example 2. Polyoxyethylene cetyl alcohol ether 25g, monoglyceride 10g, sixteen 20g, simethicone 10g, isohexadecane 60g, caprylic acid triglyceride 40g,1,3 butanediol 2g, sodium pyrrolidone carboxylate 30g, isosorbide dimethyl ether 18.75g, xanthan gum 7.5g, shea butter 40g, rhodiola rosea extract 80g, gluconic acid 10g, and the balance purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Example 3. Polyoxyethylene cetyl ether 18g, monoglyceride 16g, cetyl alcohol 15g, simethicone 15g, isohexadecane 40g, caprylic triglyceride 50g,1,3 butylene glycol 1.5g, sodium pyrrolidone carboxylate 40g, dimethyl isosorbide 15g, xanthan gum 7.5g, shea butter 32g, rhodiola rosea extract 60g, glyoxylic acid 20g, the balance being purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Comparative example 2 reference example 3
18G of polyoxyethylene cetyl alcohol ether, 16g of monoglyceride, 15g of cetyl alcohol, 15g of simethicone, 40g of isohexadecane, 50g of caprylic triglyceride, 1.5g of 1,3 butanediol, 40g of sodium pyrrolidone carboxylate, 15g of dimethyl isosorbide, 7.5g of xanthan gum, 32g of shea butter, 80g of rhodiola rosea extract and the balance of purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Comparative example 3
18G of polyoxyethylene cetyl alcohol ether, 16g of monoglyceride, 15g of cetyl alcohol, 15g of simethicone, 40g of isohexadecane, 50g of caprylic triglyceride, 1.5g of 1,3 butanediol, 40g of sodium pyrrolidone carboxylate, 15g of dimethyl isosorbide, 7.5g of xanthan gum, 32g of shea butter, 40g of rhodiola rosea extract, 20g of glycollic acid and the balance of purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Comparative example 4.
18G of polyoxyethylene cetyl alcohol ether, 16g of monoglyceride, 15g of cetyl alcohol, 15g of simethicone, 40g of isohexadecane, 50g of caprylic triglyceride, 1.5g of 1,3 butanediol, 40g of sodium pyrrolidone carboxylate, 15g of dimethyl isosorbide, 7.5g of xanthan gum, 32g of shea butter, 100g of rhodiola rosea extract, 20g of glycollic acid and the balance of purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Comparative example 5.
18G of polyoxyethylene cetyl alcohol ether, 16g of monoglyceride, 15g of cetyl alcohol, 15g of simethicone, 40g of isohexadecane, 50g of caprylic triglyceride, 1.5g of 1,3 butanediol, 40g of sodium pyrrolidone carboxylate, 15g of dimethyl isosorbide, 5g of xanthan gum, 32g of shea butter, 60g of rhodiola rosea extract, 20g of glycollic acid and the balance of purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Comparative example 6.
18G of polyoxyethylene cetyl alcohol ether, 16g of monoglyceride, 15g of cetyl alcohol, 15g of simethicone, 40g of isohexadecane, 50g of caprylic triglyceride, 1.5g of 1,3 butanediol, 40g of sodium pyrrolidone carboxylate, 7.5g of xanthan gum, 32g of shea butter, 60g of rhodiola rosea extract, 20g of glycollic acid and the balance of purified water. According to the technical scheme, 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle is 10g.
Comparative example 7.
18G of polyoxyethylene cetyl alcohol ether, 16g of monoglyceride, 15g of cetyl alcohol, 15g of simethicone, 40g of isohexadecane, 50g of caprylic triglyceride, 1.5g of 1,3 butanediol, 40g of sodium pyrrolidone carboxylate, 15g of dimethyl isosorbide, 7.5g of xanthan gum, 32g of shea butter, 60g of rhodiola rosea extract, 20g of glycollic acid and the balance of purified water. 1000g of the preparation method is prepared, split charging and bottling are carried out, and each bottle contains 10g
Step 1, adding the formula amount of monoglyceride, cetyl alcohol, simethicone, isohexadecane, caprylic acid triglyceride, 1,3 butanediol, sodium pyrrolidone carboxylate, isosorbide dimethyl ether, glycolic acid, polyoxyethylene cetyl alcohol ether, isosorbide dimethyl ether, butter fruit tree fruit oil and rhodiola rosea extract into two-thirds formula amount of purified water under stirring, and stirring for dissolution;
Step 2, adding the formula amount of xanthan gum into one third of formula amount of purified water under stirring, heating to 50 ℃, stirring and dissolving, and cooling to room temperature;
And 3, adding the mixture obtained in the step 1 into the mixture obtained in the step 2 under stirring at room temperature, and uniformly mixing to obtain the whitening and moisturizing emulsion.
Example 4 whitening Effect experiment
Experimental materials:
(1) L-dopa solution: PBS buffer was dissolved, 0.986X10-2 (g/ml);
(2) Tyrosinase solution: PBS buffer was dissolved, 3X 10-2 (g/ml);
(3) PBS buffer solution, 15.6g Na 2HPO4、35.8gNa2HPO4 is weighed to 500ml respectively, 255ml Na 2HPO4 solution and 245mlNa 2HPO4 solution are taken and mixed evenly.
And (3) respectively measuring:
(1) Accurately transferring 0.5ml of L-dopa and 5ml of PBS buffer solution by using a pipette, placing the solution into a PE tube, uniformly mixing, keeping the temperature at 37 ℃ for 20min, and rapidly measuring the absorbance value by using an ultraviolet spectrophotometer at 475nm to obtain A T1;
(2) Accurately transferring 0.5ml of L-dopa and 5ml of PBS buffer solution into a PE tube by using a pipette, uniformly mixing, keeping the temperature at 37 ℃ for 10min, then adding 0.5ml of tyrosinase, keeping the temperature at 37 ℃ for 10min, and rapidly measuring the absorbance value at 475nm by using an ultraviolet spectrophotometer to obtain A T2;
(3) Accurately removing 0.5ml of L-dopa, 5ml of PBS buffer solution, 0.5ml of each of the products of example 1/example 2/example 3/comparative example 4/comparative example 5/comparative example 6/comparative example 7 by a pipette, respectively, placing into PE pipes, uniformly mixing, keeping the temperature at 37 ℃ for 20min, and rapidly measuring absorbance value at 475nm by an ultraviolet spectrophotometer to obtain A T3;
(4) Accurately removing 0.5ml of L-dopa, 5ml of PBS buffer solution, 0.5ml of each of example 1/example 2/example 3/comparative example 4/comparative example 5/comparative example 6/comparative example 7 products by a pipette, respectively placing the products in PE pipes, uniformly mixing, keeping the temperature at 37 ℃ for 10min, then adding 0.5ml of tyrosinase, keeping the temperature at 37 ℃ for 10min, and rapidly measuring absorbance values at 475nm by an ultraviolet spectrophotometer to obtain A T4;
formula for calculating tyrosinase activity inhibition rate
Tyrosinase activity inhibition ratio= [1- (a T4-AT3)/(AT2-AT1) ] ×100%
The tyrosinase activity inhibition rates of the products of examples 1 to 3 and comparative examples 2 to 7 were calculated according to the above-mentioned formulas, respectively, and the results are shown in Table 1.
TABLE 1
Sample of | Tyrosinase activity inhibition rate,% |
Example 1 product | 34.28 |
Example 2 product | 39.41 |
Example 3 product | 39.72 |
Comparative example 2 product | 18.67 |
Comparative example 3 product | 19.02 |
Comparative example 4 product | 36.48 |
Comparative example 5 product | 39.65 |
Comparative example 6 product | 39.47 |
Comparative example 7 product | 36.58 |
Table 1 data illustrates: the products of examples 1-3, compared with the products of comparative examples 2-3, have obviously improved tyrosinase activity inhibition rate, demonstrate that the technical scheme of the invention obtains very good synergistic effect; the tyrosinase activity inhibition rate of the product of comparative example 4 shows that the tyrosinase activity inhibition rate of rhodiola rosea extract is not in direct proportion to a certain degree of increase of the consumption of rhodiola rosea extract. The results of comparative examples 5 to 6 show that the addition of xanthan gum or isosorbide dimethyl ether does not affect the tyrosinase activity inhibition rate of the product.
Example 5 stability experiment
20 Bottles of the products of examples 1 to 3 and the products of comparative examples 2 to 7 were placed in a constant temperature and humidity cabinet at 45℃and a relative humidity of 65%, and the appearance was observed by sampling on day 90, and tyrosinase activity inhibition rate (sampling test after shaking) was measured as described in example 4, and the results are recorded in Table 2.
TABLE 2
Table 2 illustrates:
(1) The products of examples 1-3 were stable in appearance and tyrosinase activity inhibition during the stability test, while the products of comparative examples 2-4 were reduced in tyrosinase activity inhibition to varying degrees;
(2) In comparative examples 5 and 6, the product is divided into an upper layer and a lower layer, and the deterioration is obvious, which shows that in the technical scheme of the invention, the mass ratio of the isosorbide dimethyl ether to the xanthan gum can obviously improve the stability of the product.
(3) The product of comparative example 7 has obvious color change in appearance and obvious reduction in tyrosinase activity inhibition rate. The preparation method has positive effect on improving the stability of the product.
Claims (6)
1. The stable whitening and moisturizing emulsion is characterized by comprising butter fruit oil, rhodiola rosea extract and fruit acid, wherein the mass ratio of the butter fruit oil to the fruit acid is 2.2-4:3-8:1-3, the dimethyl ether of isosorbide is 1-1.9%, the dimethyl silicone oil is 1.5-2%, the isohexadecane is 3-6%, the caprylic triglyceride is 4-6%, the 1, 3-butanediol is 0.1-0.2%, the sodium pyrrolidone carboxylate is 3-5%, the isosorbide dimethyl ether and the xanthan gum, the mass ratio of the butter fruit oil to the fruit acid is 2.2-4:3-8:1-3, the dimethyl ether of isosorbide is 1.5-2.5 times that of the xanthan gum, and the balance is purified water, and the fruit acid is one or more of the group consisting of the glycolic acid, the citric acid, the malic acid and the gluconic acid, and the stable whitening and moisturizing emulsion is prepared by the following steps:
Step 1, uniformly mixing monoglyceride, hexadecyl/stearyl alcohol, simethicone, isohexadecane, caprylic acid triglyceride, 1, 3-butanediol, sodium pyrrolidone carboxylate, isosorbide dimethyl ether and fruit acid according to the formula amount;
step2, adding the formula amount of polyoxyethylene cetyl alcohol ether and isosorbide dimethyl ether into two-thirds formula amount of purified water under stirring, and stirring for dissolution;
Step 3, adding the xanthan gum with the formula amount into one third of purified water with the formula amount under stirring, heating to 50 ℃, stirring and dissolving, and cooling to room temperature;
step 4, uniformly mixing the formula amount of the butter oil of the Butyrospermum parkii and the formula amount of the rhodiola rosea extract;
step 5, uniformly mixing the solutions obtained in the step 2 and the step 3 at room temperature; slowly adding the mixture into the mixture obtained in the step 1 under stirring;
And 6, adding the mixture obtained in the step 4 into the mixture obtained in the step 5 under stirring at room temperature to obtain the whitening and moisturizing emulsion.
2. The stable whitening and moisturizing emulsion of claim 1, wherein the fruit acid is selected from any of glycolic acid and gluconic acid.
3. The stable whitening and moisturizing emulsion according to claim 1, wherein the mass ratio of the butter oil of the butter tree to the rhodiola rosea extract to the fruit acid is 2.8-3.5:5-7:1.5-2.5.
4. The stable whitening and moisturizing emulsion according to claim 1, wherein the feeding mass ratio of the butter oil of the avocado tree, the rhodiola rosea extract and the fruit acid is 3.2:6:2.
5. The stable whitening and moisturizing emulsion according to claim 1, comprising 1.4-2% of polyoxyethylene cetyl ether, 1.3-1.8% of monoglyceride, 1.4-1.8% of cetyl/stearyl alcohol, 1.4-1.7% of simethicone, 4-5% of isohexadecane, 4.5-5.5% of caprylic triglyceride, 0.1-0.2% of 1, 3-butanediol, 3.5-4.5% of sodium pyrrolidone carboxylate, 1.8-2.2% of butter oil, rhodiola rosea extract and fruit acid, 2.8-3.5% of isosorbide dimethyl ether and xanthan gum, wherein the mass ratio of butter oil, rhodiola rosea extract and fruit acid is 2.8-3.5%, 1.5-2.5% of dimethyl ether of isosorbide, 1.8-2.2 times of xanthan gum, and the balance of purified water, and the percentages are mass percentages.
6. The stable whitening and moisturizing emulsion according to claim 1, which comprises 1.8% of polyoxyethylene cetyl ether, 1.6% of monoglyceride, 1.5% of cetyl/stearyl alcohol, 1.5% of simethicone, 4.0% of isohexadecane, 5.0% of caprylic triglyceride, 0.15% of 1, 3-butanediol, 4.0% of sodium pyrrolidone carboxylate, butter fruit oil, rhodiola rosea extract and fruit acid, dimethyl isosorbide and xanthan gum, wherein the mass ratio of butter fruit oil to rhodiola rosea extract to glyoxylic acid is 3.2:6:2, the mass ratio of isosorbide dimethyl ether is 1.5%, 2 times that of xanthan gum, and the balance is purified water, and the percentages are mass percentages.
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Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030012562A (en) * | 2001-08-01 | 2003-02-12 | 주식회사 웰스킨 | Whitening composition containing rhodiola sachalinensis a. bor extraction |
CN101703461A (en) * | 2009-11-20 | 2010-05-12 | 天津嘉氏堂科技有限公司 | Skin-whitening speckle-removing cream and preparation method thereof |
KR20110018091A (en) * | 2009-08-17 | 2011-02-23 | 한국식품연구원 | Composition for skin whitening |
CN102641229A (en) * | 2012-05-18 | 2012-08-22 | 通德集团有限公司 | Rhodiola crenulata toner with whitening and moisturizing effects |
CN105708768A (en) * | 2016-04-12 | 2016-06-29 | 孟根森 | Skin-whitening skin care emulsion containing collagen |
CN107106480A (en) * | 2014-10-28 | 2017-08-29 | 路博润先进材料公司 | Cosmetic composition containing Halomonas extractive from fermentative and application thereof |
CN108135816A (en) * | 2015-09-07 | 2018-06-08 | 医疗美容解决方案祖韦拉克医生公司 | For the composition comprising Isosorbide dimethyl ether, polyalcohol and phenols or Polyphenols antioxidant of local application |
CN108272719A (en) * | 2018-03-25 | 2018-07-13 | 广州市卓多姿化妆品有限公司 | A kind of whitening spot-removing anti-wrinkle face mask and preparation method thereof |
CN108670929A (en) * | 2018-07-17 | 2018-10-19 | 襄阳佰蒂生物科技股份有限公司 | A kind of blueberry essence day cream production technology |
CN111297756A (en) * | 2020-02-25 | 2020-06-19 | 刘燕 | Essence with moistening and moisturizing and anti-allergy effects and preparation method thereof |
CN112741789A (en) * | 2020-12-24 | 2021-05-04 | 广州尚品生物科技有限公司 | Anti-aging composition, preparation method and application |
CN112933022A (en) * | 2021-04-16 | 2021-06-11 | 河南董欣生物科技有限公司 | Composition for controlling oil and activating skin of face, preparation method and application |
CN113730328A (en) * | 2021-11-01 | 2021-12-03 | 广东机电职业技术学院 | Plant essence extraction process with whitening effect |
CN113897406A (en) * | 2021-09-29 | 2022-01-07 | 山东恒鲁生物科技有限公司 | Method for extracting and purifying salidroside from rhodiola rosea powder |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100260695A1 (en) * | 2009-04-09 | 2010-10-14 | Mary Kay Inc. | Combination of plant extracts to improve skin tone |
-
2022
- 2022-04-25 CN CN202210436218.6A patent/CN114748387B/en active Active
Patent Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030012562A (en) * | 2001-08-01 | 2003-02-12 | 주식회사 웰스킨 | Whitening composition containing rhodiola sachalinensis a. bor extraction |
KR20110018091A (en) * | 2009-08-17 | 2011-02-23 | 한국식품연구원 | Composition for skin whitening |
CN101703461A (en) * | 2009-11-20 | 2010-05-12 | 天津嘉氏堂科技有限公司 | Skin-whitening speckle-removing cream and preparation method thereof |
CN102641229A (en) * | 2012-05-18 | 2012-08-22 | 通德集团有限公司 | Rhodiola crenulata toner with whitening and moisturizing effects |
CN107106480A (en) * | 2014-10-28 | 2017-08-29 | 路博润先进材料公司 | Cosmetic composition containing Halomonas extractive from fermentative and application thereof |
CN108135816A (en) * | 2015-09-07 | 2018-06-08 | 医疗美容解决方案祖韦拉克医生公司 | For the composition comprising Isosorbide dimethyl ether, polyalcohol and phenols or Polyphenols antioxidant of local application |
CN105708768A (en) * | 2016-04-12 | 2016-06-29 | 孟根森 | Skin-whitening skin care emulsion containing collagen |
CN108272719A (en) * | 2018-03-25 | 2018-07-13 | 广州市卓多姿化妆品有限公司 | A kind of whitening spot-removing anti-wrinkle face mask and preparation method thereof |
CN108670929A (en) * | 2018-07-17 | 2018-10-19 | 襄阳佰蒂生物科技股份有限公司 | A kind of blueberry essence day cream production technology |
CN111297756A (en) * | 2020-02-25 | 2020-06-19 | 刘燕 | Essence with moistening and moisturizing and anti-allergy effects and preparation method thereof |
CN112741789A (en) * | 2020-12-24 | 2021-05-04 | 广州尚品生物科技有限公司 | Anti-aging composition, preparation method and application |
CN112933022A (en) * | 2021-04-16 | 2021-06-11 | 河南董欣生物科技有限公司 | Composition for controlling oil and activating skin of face, preparation method and application |
CN113897406A (en) * | 2021-09-29 | 2022-01-07 | 山东恒鲁生物科技有限公司 | Method for extracting and purifying salidroside from rhodiola rosea powder |
CN113730328A (en) * | 2021-11-01 | 2021-12-03 | 广东机电职业技术学院 | Plant essence extraction process with whitening effect |
Non-Patent Citations (4)
Title |
---|
侯红萍.《发酵食品工艺学》.中国农业大学出版社,2016,(第1版),第268页. * |
张晓峰 等.《青藏红景天 资源开发研究》.陕西科学技术出版社,2009,(第1版),第175页. * |
裘炳毅 等.《现代化妆品科学与技术》.中国轻工业出版社,2016,(第1版),第373-374页. * |
马振友 等.《皮肤美容化妆品制剂手册》.中医古籍出版社,2015,(第2版),第403页. * |
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