CN111297756A

CN111297756A - Essence with moistening and moisturizing and anti-allergy effects and preparation method thereof

Info

Publication number: CN111297756A
Application number: CN202010114391.5A
Authority: CN
Inventors: 刘燕
Original assignee: 刘燕
Current assignee: GUANGDONG KANGRONG INDUSTRIAL Co.,Ltd.
Priority date: 2020-02-25
Filing date: 2020-02-25
Publication date: 2020-06-19
Anticipated expiration: 2040-02-25
Also published as: CN111297756B

Abstract

The invention relates to an essence with the effects of moistening and anti-allergy and a preparation method thereof, wherein the essence comprises the following components: 0.5-1.0% of methyl glucose sesquistearate, 2-6% of squalane, 1-5% of polydimethylsiloxane, 1-5% of butanediol, 1-5% of glycerol, 1-3% of shea butter, 1-3% of vitamin E, 0.05-0.2% of EDT A-2Na, 0.1-0.5% of carbomer, 0.2-15% of moisturizing and anti-allergy composition, 0.2-0.4% of phenoxyethanol and 60-75% of deionized water; the moisturizing and anti-allergy composition is composed of 10-20 parts of trollius chinensis bunge extract, 2-8 parts of black sesame extract, 5-10 parts of L-fucose and 1-5 parts of sucrose fatty acid ester. The essence disclosed by the invention has obvious antiallergic, moisturizing and moisturizing effects, and the black sesame extract contained in the essence can keep good stability, so that the overall effect is improved, and the essence has a wide application prospect.

Description

Essence with moistening and moisturizing and anti-allergy effects and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to essence with moistening and anti-allergy effects and a preparation method thereof.

Background

Skin is a natural barrier of human body surface, but in recent years, along with the change of dietary structure, the diversification of cosmetics, the increase of environmental pollution and working and living pressure, people with allergy are more and more, and skin allergy becomes one of the problems which influence the health of human skin and need to be solved urgently. Physical factors such as ultraviolet light, heat, cold, mechanical damage, etc.; chemical factors such as surfactant over-degreasing, chemical agents, sunscreens, whitening agents, etc.; various factors such as bacteria, mold and the like can cause the allergic reaction generated by the skin to have symptoms such as red swelling, itching, desquamation, allergic dermatitis and the like, and particularly, the skin is dry in autumn and winter, and a plurality of people can have allergic symptoms such as skin pruritus and the like.

In view of the above-mentioned skin sensitivity problem, the prior art provides many products with anti-sensitivity efficacy, for example, chinese patent application CN108379141A discloses an anti-sensitivity cosmetic composition and a preparation method thereof, the main anti-sensitivity raw materials of the composition are peony root extract, hydrolyzed ginsenosides, honeysuckle flower extract, corydalis yanhusuo root extract, and then the composition is prepared by matching with emulsifier, stabilizer, emollient, humectant, chelating agent, skin conditioner and the like, and each component is synergistic, and has the effects of correcting skin color, moisturizing and the like; chinese patent application CN106619243A discloses a composition with moisture retention and anti-allergy functions and application thereof, the composition mainly comprises hypsizygus marmoreus extract, brown algae extract, codiales tomentosa extract, tremella sporophore extract and glacier seawater, and has the effects of locking water, moistening skin, fading fine lines, fading pigmentation and the like. However, the two moisturizing and anti-allergy compositions have poor stability due to the need of adding a plurality of different extracts, and the extracts such as the hydrolyzed ginsenosides, the corydalis yanhusuo root extract, the hypsizygus marmoreus extract and the like are expensive and have high cost, so that the application of the two moisturizing and anti-allergy compositions is greatly limited.

Therefore, the composition with the effects of moistening and moisturizing and anti-allergy and the application thereof, which have good stability and low cost, are urgently needed to be provided.

Disclosure of Invention

Based on the above, the invention aims to provide the essence which is good in stability, low in cost and has the effects of moistening and keeping moisture and resisting allergy and the preparation method thereof.

In order to achieve the purpose, the invention adopts the following technical scheme: the essence with the effects of moistening and moisturizing and anti-allergy comprises the following components in percentage by mass: 0.5-1.0% of methyl glucose sesquistearate, 2-6% of squalane, 1-5% of polydimethylsiloxane, 1-5% of butanediol, 1-5% of glycerol, 1-3% of shea butter, 1-3% of vitamin E, 0.05-0.2% of EDTA-2Na, 0.1-0.5% of carbomer, 0.2-15% of moisturizing and anti-allergy composition, 0.2-0.4% of phenoxyethanol and 60-75% of deionized water; the moisturizing and anti-allergy composition is composed of 10-20 parts of trollius chinensis bunge extract, 2-8 parts of black sesame extract, 5-10 parts of L-fucose and 1-5 parts of sucrose fatty acid ester.

Further, the essence comprises the following components in percentage by mass: 0.5-0.8% of methyl glucose sesquistearate, 2-3% of squalane, 2-4% of polydimethylsiloxane, 2-4% of butanediol, 2-4% of glycerol, 1-2.5% of shea butter, 2-3% of vitamin E, 0.1-0.2% of EDTA-2Na, 0.1-0.3% of carbomer, 5-15% of moisturizing and anti-allergic composition, 0.2-0.3% of phenoxyethanol and 60-75% of deionized water; the moisturizing and anti-allergy composition is composed of 12-16 parts of trollius chinensis bunge extract, 4-6 parts of black sesame extract, 6-9 parts of L-fucose and 2-4 parts of sucrose fatty acid ester.

Further, the essence comprises the following components in percentage by mass: 0.8% of methyl glucose sesquistearate, 3.0% of squalane, 4.0% of polydimethylsiloxane, 3% of butanediol, 2.5% of glycerol, 2.0% of shea butter, 3.0% of vitamin E, 0.15% of EDTA-2Na, 0.2% of carbomer, 12% of moisturizing and anti-allergic composition, 0.2% of phenoxyethanol and 69.15% of deionized water; the moisturizing and anti-allergy composition is composed of 15 parts of trollius chinensis bunge extract, 5 parts of black sesame extract, 8 parts of L-fucose and 3 parts of sucrose fatty acid ester.

Further, the preparation method of the trollius chinensis bunge extract comprises the following steps:

drying and crushing the trollius chinensis bunge, adding water for reflux extraction for 1-2 h, filtering, adding water into filter residues for reflux extraction for 0.5-1 h, filtering, combining the two filtrates, concentrating, adding absolute ethyl alcohol with the volume ratio of 1 (4-5) into the concentrate, uniformly mixing, placing at 1-4 ℃ for precipitation for 8-12 h, centrifuging, dissolving the lower-layer precipitate with water at 60-75 ℃, and concentrating to obtain the trollius chinensis bunge.

Further, the trollius chinensis bunge extract obtained after concentration has the relative density of (1.10-1.20) g/cm³。

Further, the volume ratio of the concentrate to the absolute ethyl alcohol is 1: 4.

Further, the preparation method of the black sesame extract comprises the following steps:

crushing ripe black sesame, adding the crushed black sesame into an extraction kettle of a supercritical carbon dioxide extraction instrument, setting the temperature of the extraction kettle to be 40-55 ℃, the temperature of a separation kettle to be 30-45 ℃, and the pressure to be 30-50 MPa, circularly extracting for 2-5 hours, and collecting an extract.

Further, the temperature of the extraction kettle is 50 ℃; and/or the temperature of the separation kettle is 35 ℃; and/or the pressure is 30 MPa; and/or the extraction time was 4 h.

The invention also provides a method for preparing the essence, which comprises the following steps:

A) adding methyl glucose sesquistearate, squalane, polydimethylsiloxane, shea butter and vitamin E into an oil phase pot, uniformly stirring, heating to 80-85 ℃, and preserving heat for later use;

B) adding deionized water into a water phase pot, slowly adding carbomer while stirring, heating, uniformly dispersing, adding the moisturizing and anti-allergy composition, butanediol, glycerol and EDTA-2Na, heating to 80-85 ℃, keeping the temperature for 20-40 min, filtering, pumping into an emulsifying pot, slowly adding the material prepared in the step A) while stirring, and homogenizing and emulsifying for 5-10 min; and after homogenizing, slowly cooling to 40-45 ℃, adding phenoxyethanol, uniformly stirring, discharging after detection is qualified, and filling.

In the essence, the trollius chinensis bunge is flower of perennial herb Chinese trollius chinensis bunge of Ranunculaceae, and contains very many functional components, such as flavonoid components of orientin, vitexin, alkaloid, resin, palmitic acid, coumarin and glycosides thereof, polysaccharide, volatile oil, tannin, various alcohol compounds and the like. The trollius chinensis is bitter in taste and cool in nature, has the functions of clearing away heat and toxic materials, resisting bacteria and diminishing inflammation, and has strong inhibiting effect on pneumococcus, pseudomonas aeruginosa, catacoccus and the like; has obvious curative effect on acute and chronic tonsillitis, pharyngitis, acute otitis media, conjunctivitis, upper respiratory tract infection and other diseases, and has rich resources and wide application in pharmacy.

Black sesame is a black seed of benne of the family benaceae, is planted in various places in China, is rich in resources, contains sesamin which is a lignanoid substance existing in sesame or sesame oil, has the effects of reducing cholesterol, detoxifying, protecting the liver, resisting hypertension and the like, is widely applied to the fields of health products, foods, medicines, sanitation and the like, is easily influenced by temperature, and has poor stability.

The two plants are less in application in the field of cosmetics, and in order to find greater application value of the two plants, the inventor finds that after a large amount of creative work, the trollius chinensis bunge is mixed with the black sesame extract after being extracted, and then the mixture is matched with sucrose fatty acid ester and L-fucose to prepare a composition, so that the composition has remarkable antiallergic, moisturizing and moisturizing effects, and can keep better stability of the black sesame extract. Through experimental research, the inventor believes that the combination of the trollius chinensis bunge extract, the black sesame extract and the L-fucose has the functions of anti-allergy, moistening and moisturizing, and after the sucrose fatty acid ester is added, the compatibility and the stability of the trollius chinensis bunge extract, the black sesame extract and the L-fucose can be improved, and the anti-allergy and moisturizing effects of the whole composition can be enhanced.

Therefore, the invention has the following beneficial effects:

the essence with the effects of moistening and moisturizing and anti-allergy provided by the invention is prepared by mixing the extracted trollius chinensis and the black sesame extract and then adding the sucrose fatty acid ester and the L-fucose to prepare the composition, has obvious anti-allergy, moistening and moisturizing effects, can keep better stability of the black sesame extract, improves the overall effect, is rich in raw material resources, is lower in cost and has wide application prospect.

Detailed Description

The present invention will be described in further detail below with reference to specific embodiments of examples. It should not be understood that the scope of the above-described subject matter of the present invention is limited to the following examples.

In the examples, the experimental methods used were all conventional methods unless otherwise specified, and the materials, reagents and the like used were commercially available without otherwise specified.

Example 1A composition having moisturizing, anti-allergic effects

The composition with the effects of moistening and keeping moisture and resisting allergy comprises the following components in parts by weight: 15 parts of trollius chinensis bunge extract, 5 parts of black sesame extract, 8 parts of L-fucose and 3 parts of sucrose fatty acid ester.

The preparation method comprises the following steps:

s1, drying flos Trollii, pulverizing, extracting with 1:50g/ml water under reflux for 2h, filtering, extracting the residue with 1:50g/ml water under reflux for 1h, filtering, mixing the filtrates, concentrating, adding 1:4 absolute ethanol into the concentrate, mixing, precipitating at 4 deg.C for 12h, centrifuging, dissolving the lower precipitate with 70 deg.C water, and concentrating to obtain extract with relative density of 1.12g/cm³The trollius chinensis bunge extract;

s2, crushing ripe black sesame, adding the crushed black sesame into an extraction kettle of a supercritical carbon dioxide extraction instrument, setting the temperature of the extraction kettle to be 50 ℃, the temperature of a separation kettle to be 35 ℃, and the pressure to be 30MPa, circularly extracting for 4 hours, and collecting black sesame extract;

s3, mixing the trollius chinensis bunge extract obtained in the step S1, the black sesame extract obtained in the step S2, L-fucose and sucrose fatty acid ester according to parts by weight.

Example 2A composition with moisturizing, anti-allergic effects

The composition with the effects of moistening and keeping moisture and resisting allergy comprises the following components in parts by weight: 20 parts of trollius chinensis bunge extract, 2 parts of black sesame extract, 5 parts of L-fucose and 5 parts of sucrose fatty acid ester.

The preparation method comprises the following steps:

s1, drying flos Trollii, pulverizing, extracting with 1:50g/ml water under reflux for 1.5 hr, filtering, extracting the residue with 1:50g/ml water under reflux for 1 hr, filtering, mixing the filtrates, concentrating, adding 1:4 anhydrous ethanol into the concentrate, mixing, precipitating at 4 deg.C for 12 hr, centrifuging, dissolving the lower precipitate with 65 deg.C water, and concentrating to obtain extract with relative density of 1.11g/cm³The trollius chinensis bunge extract;

s2, crushing ripe black sesame, adding the crushed black sesame into an extraction kettle of a supercritical carbon dioxide extraction instrument, setting the temperature of the extraction kettle to be 45 ℃, the temperature of a separation kettle to be 30 ℃, and the pressure to be 35MPa, circularly extracting for 5 hours, and collecting black sesame extract;

Example 3A composition with moisturizing, anti-allergic effects

The composition with the effects of moistening and keeping moisture and resisting allergy comprises the following components in parts by weight: 10 parts of trollius chinensis bunge extract, 8 parts of black sesame extract, 10 parts of L-fucose and 2 parts of sucrose fatty acid ester.

The preparation method comprises the following steps:

s1, drying flos Trollii, pulverizing, extracting with 1:50g/ml water under reflux for 2h, filtering, extracting the residue with 1:50g/ml water under reflux for 1h, filtering, mixing the filtrates, concentrating, adding 1:4 absolute ethanol into the concentrate, mixing, precipitating at 4 deg.C for 12h, centrifuging, dissolving the lower precipitate with 75 deg.C water, and concentrating to obtain extract with relative density of 1.15g/cm³The trollius chinensis bunge extract;

s2, crushing ripe black sesame, adding the crushed black sesame into an extraction kettle of a supercritical carbon dioxide extraction instrument, setting the temperature of the extraction kettle to be 55 ℃, the temperature of a separation kettle to be 40 ℃, and the pressure to be 40MPa, circularly extracting for 3 hours, and collecting black sesame extract;

Example 4 essence with moistening, moisturizing and anti-allergy effects

The preparation method comprises the following steps:

A) adding methyl glucose sesquistearate, squalane, polydimethylsiloxane, shea butter and vitamin E into an oil phase pot, stirring uniformly, heating to 85 ℃, and preserving heat for later use;

B) adding deionized water into a water phase pot, slowly adding carbomer while stirring, heating, dispersing uniformly, adding the moisture-keeping and anti-allergy composition, butanediol, glycerol and EDTA-2Na, heating to 85 deg.C, keeping the temperature for 30min, filtering, pumping into an emulsifying pot, slowly adding the material prepared in step A) while stirring, and homogenizing and emulsifying for 8 min; slowly cooling to 45 deg.C after homogenizing, adding phenoxyethanol, stirring, discharging after detecting, and bottling.

Example 5 essence with moistening, moisturizing and anti-allergy effects

The preparation method is shown in reference example 4.

Example 6 essence with moistening, moisturizing and anti-allergy effects

The preparation method is shown in reference example 4.

Comparative example 1A composition

The difference from example 1 is that the composition of comparative example 1 does not contain black sesame extract, and other parameters and operations refer to example 1.

Comparative example 2A composition

The difference from example 1 is that comparative example 2 replaces the black sesame extract in the composition with a black sesame extract, which has the following specific steps:

crushing ripe black sesame, adding petroleum ether with a weight-volume ratio of 1:5g/ml, performing reflux extraction for 3 hours, extracting for 2 times, combining filtrates, putting the filtrates on a silica gel column, washing with petroleum ether, eluting with a mixed solution of petroleum ether and ethyl acetate of 9:1, and purifying the eluent to obtain a black sesame extract;

other parameters and operations refer to example 1.

Comparative example 3A composition

The difference from example 1 is that the composition of comparative example 3 does not contain the trollius chinensis bunge extract, and other parameters and operations refer to example 1.

Comparative example 4A composition

The difference from example 1 is that sucrose fatty acid ester was not added to the composition of comparative example 4, and other parameters and operations were in reference to example 1.

Comparative example 5A composition

The difference from example 1 is that no L-fucose was added to the composition of comparative example 5, and other parameters and operations refer to example 1.

Comparative examples 6-10 essence

The difference from example 4 is that the moisturizing and anti-allergy composition in example 4 is replaced by the compositions prepared in comparative examples 1 to 5 to respectively prepare the essences of comparative examples 6 to 10, and other parameters and operations refer to example 4.

Experimental example 1 measurement of skin irritation index (PII)

The compositions prepared in examples 1 to 3 of the present invention and comparative examples 1 to 5 were subjected to a skin irritation index (PII) measurement according to the closed sensitization test method specified in GB/T16886.10-2000, and the test results are shown in Table 1.

TABLE 1 skin irritation index (PII) measurement results

Test items	Index of skin irritation	Skin sensitization
			Example 1	0	Is free of
Example 2	0	Is free of
			Example 3	0	Is free of
Comparative example 1	0	Is free of
			Comparative example 2	0	Is free of
Comparative example 3	0	Is free of
			Comparative example 4	0	Is free of
Comparative example 5	0	Is free of

As can be seen from Table 1, the compositions prepared in examples 1 to 3 of the present invention and comparative examples 1 to 5 have no skin irritation or skin sensitization.

Experimental example 2 anti-allergic Effect test of composition

1. Experimental materials: the compositions prepared in examples 1 to 3 and comparative examples 1 to 5.

2. Subject: SPF mice, 18-22 g, half male and half female.

3. The experimental method comprises the following steps:

SPF mice were randomly divided into a blank group, a model group, a positive control group (compound dexamethasone acetate, purchased from Huarun Sanjiu medicine, Inc.), examples 1-3 groups and comparative examples 1-5 groups, each group containing 10 mice. The belly and back of the mouse are unhaired 24h before the experiment, and the range is about 3 multiplied by 3cm²On the next day, 0.05ml of 5% 2, 4-dinitrochlorobenzene solution was applied evenly to the abdominal depilatory site of mice for sensitization (normal group was replaced with equal amount of distilled water), and on day 2, the treatment was performed 1 time for enrichment. 1 day before sensitization, mice were coated with the corresponding test samples 1 time per day (model group was replaced with equal amount of distilled water) at a dose of 0.5g/kg for 7 consecutive days. 1h after the last administration, 0.02ml of 1 percent 2, 4-dinitrochlorobenzene solution is evenly smeared on the right and reverse sides of the left ear of the mouse, the mouse is killed by cervical dislocation after 24h, the two ears are cut along the auricle, the hole is punched, the weight is weighed, and the mass difference between the left ear and the right ear is calculated as the swelling degree. Thymus and spleen are obtained through dissection and weighed, and thymus index and spleen index are calculated.

4. The experimental results are as follows: see table 2 for results.

TABLE 2 anti-allergic Effect test results for compositions

Group of	Swelling degree of ear (mg)	Spleen index (mg/10g)	Thymus index (mg/10g)
				Blank group	0.52±0.06	29.63±6.85	23.56±2.93
Model set	5.37±1.43^##	54.14±1.82^##	46.07±2.15^##
				Positive control group	1.42±0.74^**	30.38±1.34^**	24.84±1.16^**
Example 1	2.67±0.97^**	33.74±1.57^**	24.62±1.47^**
				Example 2	2.51±1.24^**	35.06±1.28^**	26.33±1.58^**
Example 3	2.64±1.19^**	34.68±1.66^**	27.54±1.51^**
				Comparative example 1	4.82±0.88	50.67±2.04	41.06±2.04
Comparative example 2	4.05±1.13	43.98±1.76	35.83±1.83
				Comparative example 3	4.37±1.74	47.34±1.95	36.42±1.67
Comparative example 4	3.24±1.25^*	37.26±1.63^*	31.88±1.71^*
				Comparative example 5	3.46±1.32^*	39.85±1.72^*	32.57±1.65^*

Note: in comparison to the blank set, the data is,^#P<0.05，^##P<0.01; in comparison to the set of models,^*P<0.05，^**P<0.01。

as can be seen from the table 2, the composition prepared in the embodiments 1 to 3 can significantly reduce the ear swelling degree, the spleen index and the thymus index of an allergic mouse model, has the effect similar to that of the positive control medicament compound dexamethasone acetate, and has a significant anti-allergy effect; after the composition of the composition is changed in the comparative examples 1 to 5, the anti-allergy effect is remarkably reduced, wherein the comparative examples 1 to 3 have no obvious anti-allergy effect.

Experimental example 3 essence moisturizing and moisturizing effect test

1. Experimental materials: the essence prepared in example 4 and comparative examples 6 to 10.

2. Subject: 180 healthy volunteers aged 24-45.

3. The experimental method comprises the following steps:

the volunteers were randomly divided into 6 groups according to the parallel control principle, 30 persons were each treated with the essence prepared in example 4 and comparative examples 6 to 10, and the essence was applied to the face after cleansing in the morning and evening every day for 4 weeks, and the moisture content of the skin before (0 weeks) and after 4 weeks was measured, respectively, to calculate the average moisture increase of the skin after 4 weeks of application, using a skin moisture tester Corneometer CM825 manufactured by COURAGE + AZKHAKA (CK) of Germany.

4. The experimental results are as follows: see table 3 for results.

Table 3 test results of the moisturizing effect of the essence

Group of	Average skin moisture increment (%)
		Example 4	7.6
Comparative example 6	3.0
		Comparative example 7	5.8
Comparative example 8	1.6
		Comparative example 9	6.1
Comparative example 10	3.4

As can be seen from table 3, the essence prepared in example 4 of the present invention can significantly increase the moisture content of the skin, and moisturize the skin, whereas the essence prepared in comparative examples 6 to 10 by changing the composition has significantly reduced moisturizing and moisturizing effects.

Experimental example 4 essence stability test

1. Experimental materials: example 4 and comparative examples 7-10.

2. The experimental method comprises the following steps:

the compositions prepared in example 4 and comparative examples 7 to 10 were allowed to stand at 25. + -.2 ℃ and relative humidity of 60. + -.10% for 12 months, and sampled at 0, 3, 6 and 12 months, and the sesamin content in the serum was measured by referring to comparative study on the determination of sesamin content in black sesame by different extraction methods (Huangxianxiao, Huangchongcai, Zhengjuqiong, different extraction methods comparative study on the determination of sesamin content in black sesame [ J ] applied chemical engineering, 2013(8): 1550-.

3. The experimental results are as follows: see table 4 for results.

Table 4 serum stability test results

As can be seen from table 4, after the essence prepared in example 4 of the present invention is placed for 12 months, sesamin contained in the essence is substantially unchanged from month 0, and still remains above 95%, and the stability is good; the sesamin content of the essence of comparative examples 8-10 is gradually reduced, wherein the reduction degree of comparative example 9 is most obvious.

The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.

Claims

1. The essence with the effects of moistening and moisturizing and anti-allergy is characterized by comprising the following components in percentage by mass: 0.5-1.0% of methyl glucose sesquistearate, 2-6% of squalane, 1-5% of polydimethylsiloxane, 1-5% of butanediol, 1-5% of glycerol, 1-3% of shea butter, 0-3% of vitamin E1, 0.05-0.2% of EDT A-2Na, 0.1-0.5% of carbomer, 0.2-15% of moisturizing and anti-allergic composition, 0.2-0.4% of phenoxyethanol and 60-75% of deionized water; the moisturizing and anti-allergy composition is composed of 10-20 parts of trollius chinensis bunge extract, 2-8 parts of black sesame extract, 5-10 parts of L-fucose and 1-5 parts of sucrose fatty acid ester.

2. The essence of claim 1, which comprises the following components in percentage by mass: 0.5-0.8% of methyl glucose sesquistearate, 2-3% of squalane, 2-4% of polydimethylsiloxane, 2-4% of butanediol, 2-4% of glycerol, 1-2.5% of shea butter, 2-3% of vitamin E, 0.1-0.2% of EDTA-2Na, 0.1-0.3% of carbomer, 5-15% of moisturizing and anti-allergic composition, 0.2-0.3% of phenoxyethanol and 60-75% of deionized water; the moisturizing and anti-allergy composition is composed of 12-16 parts of trollius chinensis bunge extract, 4-6 parts of black sesame extract, 6-9 parts of L-fucose and 2-4 parts of sucrose fatty acid ester.

3. The essence of claim 2, which comprises the following components in percentage by mass: 0.8% of methyl glucose sesquistearate, 3.0% of squalane, 4.0% of polydimethylsiloxane, 3% of butanediol, 2.5% of glycerol, 2.0% of shea butter, 3.0% of vitamin E, 0.15% of EDTA-2Na, 0.2% of carbomer, 12% of moisturizing and anti-allergic composition, 0.2% of phenoxyethanol and 69.15% of deionized water; the moisturizing and anti-allergy composition is composed of 15 parts of trollius chinensis bunge extract, 5 parts of black sesame extract, 8 parts of L-fucose and 3 parts of sucrose fatty acid ester.

4. The essence of any one of claims 1 to 3, wherein the preparation method of the trollius chinensis bunge extract comprises the following steps:

5. The essence of claim 4, wherein the concentrated trollius chinensis bunge extract has a relative density of (1.10-1.20) g/cm³。

6. The essence of claim 4, wherein the volume ratio of the concentrate to absolute ethanol is 1: 4.

7. The essence of any one of claims 1 to 3, wherein the preparation method of the black sesame extract comprises the following steps:

8. The essence of claim 7, wherein the extraction kettle temperature is 50 ℃; and/or the temperature of the separation kettle is 35 ℃; and/or the pressure is 30 MPa; and/or the extraction time was 4 h.

9. A method for preparing the essence according to any one of claims 1 to 8, comprising the following steps: