CN114302749A - 使用了化学交联海藻酸的移植用器件 - Google Patents

使用了化学交联海藻酸的移植用器件 Download PDF

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Publication number
CN114302749A
CN114302749A CN202080046753.XA CN202080046753A CN114302749A CN 114302749 A CN114302749 A CN 114302749A CN 202080046753 A CN202080046753 A CN 202080046753A CN 114302749 A CN114302749 A CN 114302749A
Authority
CN
China
Prior art keywords
formula
alginic acid
transplantation
compound
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080046753.XA
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English (en)
Chinese (zh)
Inventor
霜田雅之
安嶋久美子
古迫正司
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
National Center for Global Health and Medicine
Original Assignee
Mochida Pharmaceutical Co Ltd
National Center for Global Health and Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd, National Center for Global Health and Medicine filed Critical Mochida Pharmaceutical Co Ltd
Publication of CN114302749A publication Critical patent/CN114302749A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
CN202080046753.XA 2019-06-28 2020-06-26 使用了化学交联海藻酸的移植用器件 Pending CN114302749A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019122063 2019-06-28
JP2019-122063 2019-06-28
PCT/JP2020/025324 WO2020262642A1 (ja) 2019-06-28 2020-06-26 化学架橋アルギン酸を用いた移植用デバイス

Publications (1)

Publication Number Publication Date
CN114302749A true CN114302749A (zh) 2022-04-08

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Family Applications (1)

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CN202080046753.XA Pending CN114302749A (zh) 2019-06-28 2020-06-26 使用了化学交联海藻酸的移植用器件

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US (1) US20220409773A1 (enExample)
EP (1) EP3991792B1 (enExample)
JP (2) JP7210095B2 (enExample)
CN (1) CN114302749A (enExample)
CA (1) CA3144606A1 (enExample)
WO (1) WO2020262642A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020262642A1 (ja) * 2019-06-28 2020-12-30 持田製薬株式会社 化学架橋アルギン酸を用いた移植用デバイス
JP2023015413A (ja) * 2019-12-18 2023-02-01 持田製薬株式会社 化学架橋アルギン酸ゲルファイバ
KR102830487B1 (ko) * 2020-01-16 2025-07-08 삼성전자주식회사 세포 클러스터를 이용한 생체 전자약 장치
CN116710110A (zh) * 2020-12-28 2023-09-05 持田制药株式会社 新型的多层聚合物涂层交联海藻酸凝胶纤维
US20250154453A1 (en) * 2021-12-28 2025-05-15 Pormedtec Co., Ltd. Method for producing transplant material, and transplant material

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JP2000507202A (ja) * 1995-12-07 2000-06-13 エンセル，インコーポレイテッド 生体人工装置及びそのための細胞マトリックス
WO2014146677A1 (en) * 2013-03-18 2014-09-25 Koc Universitesi Peg hydrogels functionalized with glucagon and rgds-tetrapeptide and containing stem cells for islet coating
CN105078923A (zh) * 2014-05-07 2015-11-25 中国科学院大连化学物理研究所 Peg原位共价接枝的海藻酸盐微胶囊及其制备和应用
WO2017165389A2 (en) * 2016-03-24 2017-09-28 Millennium Pharmaceuticals, Inc. Alginate hydrogel compositions
CN109922792A (zh) * 2016-09-14 2019-06-21 洛桑联邦理工学院 基于官能化多糖的水凝胶

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US5589591A (en) 1986-07-03 1996-12-31 Advanced Magnetics, Inc. Endotoxin-free polysaccharides
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JPH09324001A (ja) 1996-04-02 1997-12-16 Kyowa Hakko Kogyo Co Ltd ヒアルロン酸ナトリウムの精製法
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JP2005036036A (ja) 2003-07-16 2005-02-10 Tanabe Seiyaku Co Ltd エンドトキシン除去方法
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JP2013151468A (ja) 2011-11-30 2013-08-08 Agilent Technologies Inc オリゴマーの合成及び精製の新規方法
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WO2020262642A1 (ja) * 2019-06-28 2020-12-30 持田製薬株式会社 化学架橋アルギン酸を用いた移植用デバイス

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JP2000507202A (ja) * 1995-12-07 2000-06-13 エンセル，インコーポレイテッド 生体人工装置及びそのための細胞マトリックス
WO2014146677A1 (en) * 2013-03-18 2014-09-25 Koc Universitesi Peg hydrogels functionalized with glucagon and rgds-tetrapeptide and containing stem cells for islet coating
CN105078923A (zh) * 2014-05-07 2015-11-25 中国科学院大连化学物理研究所 Peg原位共价接枝的海藻酸盐微胶囊及其制备和应用
WO2017165389A2 (en) * 2016-03-24 2017-09-28 Millennium Pharmaceuticals, Inc. Alginate hydrogel compositions
CN109922792A (zh) * 2016-09-14 2019-06-21 洛桑联邦理工学院 基于官能化多糖的水凝胶

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EP3991792A4 (en) 2023-07-12
JP7210095B2 (ja) 2023-01-23
CA3144606A1 (en) 2020-12-30
JP2023041070A (ja) 2023-03-23
JPWO2020262642A1 (enExample) 2020-12-30
US20220409773A1 (en) 2022-12-29
EP3991792B1 (en) 2025-06-25
WO2020262642A1 (ja) 2020-12-30
EP3991792C0 (en) 2025-06-25
EP3991792A1 (en) 2022-05-04

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