CN114072416A - 使用正痘病毒主要组织相容性复合物（mhc）i类样蛋白（omcp）和肿瘤特异性结合伴侣的双特异性融合蛋白 - Google Patents

使用正痘病毒主要组织相容性复合物（mhc）i类样蛋白（omcp）和肿瘤特异性结合伴侣的双特异性融合蛋白 Download PDF

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CN114072416A
CN114072416A CN202080029631.XA CN202080029631A CN114072416A CN 114072416 A CN114072416 A CN 114072416A CN 202080029631 A CN202080029631 A CN 202080029631A CN 114072416 A CN114072416 A CN 114072416A
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亚历山大·萨沙·克鲁普尼克
埃里克·里德·拉泽尔
莎拉·海因
丹尼尔·马文·沃金斯
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Krill Treatment Co ltd
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CN202080029631.XA 2019-02-18 2020-02-18 使用正痘病毒主要组织相容性复合物（mhc）i类样蛋白（omcp）和肿瘤特异性结合伴侣的双特异性融合蛋白 Pending CN114072416A (zh)

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Application Number Priority Date Filing Date Title
US201962807190P 2019-02-18 2019-02-18
US62/807,190 2019-02-18
PCT/US2020/018680 WO2020172189A1 (en) 2019-02-18 2020-02-18 BISPECIFIC FUSION PROTEIN USING ORTHOPOXVIRUS MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS l-LIKE PROTEIN (OMCP) AND TUMOR-SPECIFIC BINDING PARTNER

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US (2) US20230002450A1 (https=)
EP (1) EP3927722A4 (https=)
JP (1) JP2022520978A (https=)
KR (1) KR20210131373A (https=)
CN (1) CN114072416A (https=)
AU (1) AU2020226493B2 (https=)
CA (1) CA3130582A1 (https=)
GB (1) GB2596001B (https=)
IL (1) IL285668A (https=)
SG (1) SG11202108878VA (https=)
WO (1) WO2020172189A1 (https=)

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CN110248671A (zh) * 2017-01-04 2019-09-17 杭州康万达医药科技有限公司 包含溶瘤痘病毒和nk细胞的治疗剂及其在治疗肿瘤和/或癌症的药物中的应用

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AU2018219887B2 (en) 2017-02-08 2024-08-15 Dragonfly Therapeutics, LLC Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
BR112020015994A2 (pt) 2018-02-08 2020-12-15 Dragonfly Therapeutics, Inc. Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer
CA3237846A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
WO2019164930A1 (en) 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
KR20210018275A (ko) * 2018-05-07 2021-02-17 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양-연관 항원에 결합하는 단백질
KR102835308B1 (ko) 2018-08-08 2025-07-21 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
EP3833392A4 (en) 2018-08-08 2022-05-18 Dragonfly Therapeutics, Inc. MULTISPECIFIC BINDING PROTEINS FOR BINDING CD33, NKG2D AND CD16 AND METHODS OF USE
JP7512394B2 (ja) 2020-05-06 2024-07-08 ドラゴンフライ セラピューティクス， インコーポレイテッド Ｎｋｇ２ｄ、ｃｄ１６及びｃｌｅｃ１２ａに結合するタンパク質
EP4301774A4 (en) 2021-03-03 2025-08-13 Dragonfly Therapeutics Inc METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN
WO2022258691A1 (en) 2021-06-09 2022-12-15 Innate Pharma Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a

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Publication number Priority date Publication date Assignee Title
CN110248671A (zh) * 2017-01-04 2019-09-17 杭州康万达医药科技有限公司 包含溶瘤痘病毒和nk细胞的治疗剂及其在治疗肿瘤和/或癌症的药物中的应用
CN110248671B (zh) * 2017-01-04 2023-07-04 杭州康万达医药科技有限公司 包含溶瘤痘病毒和nk细胞的治疗剂及其在治疗肿瘤和/或癌症的药物中的应用

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KR20210131373A (ko) 2021-11-02
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AU2020226493A1 (en) 2021-10-14
CA3130582A1 (en) 2020-08-27
AU2020226493B2 (en) 2025-10-23
IL285668A (en) 2021-10-31
GB2596001A8 (en) 2022-08-24
US20260008822A1 (en) 2026-01-08
WO2020172189A1 (en) 2020-08-27
US20230002450A1 (en) 2023-01-05
SG11202108878VA (en) 2021-09-29
GB2596001A (en) 2021-12-15
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