CN113975220A - Anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation product and application thereof - Google Patents
Anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation product and application thereof Download PDFInfo
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Abstract
The invention discloses an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product and application thereof. The anti-aging composition comprises, by weight, 0.1-20 parts of hydroxypropyl tetrahydropyrane triol, 0.1-20 parts of schizosaccharomyces cerevisiae fermentation product lysate, 0.1-20 parts of lactobacillus fermentation filtrate, 1-30 parts of yeast/rice fermentation product filtrate, 1-20 parts of butanediol and 20-70 parts of deionized water. The anti-aging composition containing hydroxypropyl tetrahydropyrane triol and the fermentation product can be applied to various skin care formulations such as essence water, essence liquid, emulsion, cream and the like. The anti-aging composition has complementary action mechanisms, and has the anti-aging effects of promoting collagen synthesis, scavenging free radicals, accelerating skin renewal, and repairing skin barrier.
Description
Technical Field
The invention relates to a skin care product and application thereof, belongs to the technical field of daily chemicals, and particularly relates to an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product and application thereof in the skin care product.
Background
All organisms in nature follow the process from birth, growth, development, maturation, aging to death, as do humans. With the age, after reaching the mature stage, the human body starts to be physiologically aged, the structure and the function of each part of the body are continuously changed, wherein the skin is aged most obviously, the skin loses elasticity and obvious wrinkles appear. Skin aging is generally thought to be caused by multiple factors: aging caused by non-resistant factors existing in the body such as genetics, gravity, endocrine and immune functions, etc. with age; the action of ultraviolet rays accelerates the process of natural aging, and a series of environmental exposures such as climate change, environmental pollution and the like also have direct influence on the photoaging of the skin.
The development of modern science and technology promotes the improvement of the living standard of people, people are more and more interested in appearance, and beauty and skin care cosmetics with various efficacies are produced and are developed towards the direction of naturalization, nutrition and curative effect. The anti-aging product is used for inhibiting the premature aging of the skin by supplementing nutrients to the skin at a proper time.
At present, a plurality of skin care products on the market are added with some plant extract, and then the skin care products are alleged to have certain efficacy, however, human skin, especially horny layer, is a natural barrier to resist external harmful substances from invading into the body, the barrier effect of the skin makes most skin care products not easy to penetrate through the human skin, and the effective components of the plant extract, especially high molecular substances and water-soluble substances, are difficult to be absorbed through the skin, so that the actual efficacy is very little.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, the anti-aging composition has complementary action mechanisms, and has the anti-aging effects of promoting collagen synthesis, eliminating free radicals, accelerating skin renewal and repairing skin barriers by combined application.
The invention also aims to provide a preparation method and application of the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products, the preparation method is simple, the production time is saved, the stability of active ingredients can be kept in the preparation process, and the composition has obvious anti-aging and wrinkle-removing effects.
The technical scheme adopted by the invention is as follows:
an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product comprises the following raw materials in parts by weight:
0.1-20 parts by weight of hydroxypropyl tetrahydropyrane triol;
0.1-20 parts by weight of a split yeast fermentation product lysate;
0.1-20 parts of lactobacillus fermentation filtrate;
1-30 parts by weight of yeast/rice fermentation product filtrate;
1-20 parts of butanediol;
20-70 parts of deionized water.
Further, the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products is characterized by comprising the following raw materials in parts by weight:
0.1-10 parts by weight of hydroxypropyl tetrahydropyrane triol;
0.5-10 parts by weight of a split yeast fermentation product lysate;
0.2-10 parts of lactobacillus fermentation filtrate;
1-20 parts by weight of yeast/rice fermentation product filtrate;
5-15 parts of butanediol;
35-60 parts of deionized water.
In addition, the invention also discloses a preparation method of the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products, which comprises the following steps:
1) dissolving hydroxypropyl tetrahydropyrane triol and butanediol in deionized water, and uniformly stirring to prepare a hydroxypropyl tetrahydropyrane triol solution, namely a component A;
2) adding the lysate of the yeast fermentation product of the second split, the lactic acid bacteria fermentation filtrate, the yeast/rice fermentation product filtrate and the component A into deionized water in sequence, and stirring uniformly to obtain the anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product.
Further, in the step 1), the stirring speed is 20-80r/min, and in the step 2), the stirring speed is 30-100 r/min.
Further, in the step 2), the mass ratio of the total mass of the 4 raw materials of the hydroxypropyl tetrahydropyrane triol, the cracked yeast fermentation product lysate, the lactic acid bacteria fermentation filtrate and the yeast/rice fermentation product filtrate to the water is 1: 0.5-2.5.
Further, in the step 2), the mass ratio of the total mass of the 4 raw materials of the hydroxypropyl tetrahydropyrane triol, the cracked yeast fermentation product lysate, the lactic acid bacteria fermentation filtrate and the yeast/rice fermentation product filtrate to the water is 1: 2.
An anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation product is applied to skin care products, wherein the skin care products comprise 10-40% of the anti-aging composition according to the total weight of the skin care products; and 60-90% of conventional auxiliary materials in the field of skin care products.
Further, the conventional auxiliary materials comprise a surfactant, a thickening agent, a conditioning agent, a humectant, a preservative, a chelating agent, essence and deionized water.
Further, the skin care product is prepared into various dosage forms of toner, smoothing toner, firming toner, nourishing cream, massage cream, essence, eye cream, eye essence, cleansing cream, cleansing foam, cleansing water, facial mask, pressed powder, body lotion, body cream, body oil, body lotion and body essence.
Further, the skin care product is prepared into anti-aging wrinkle-lightening essence which comprises the following raw material components:
the anti-aging wrinkle-lightening essence is prepared by the following steps:
1) mixing deionized water, sodium hyaluronate, xanthan gum and allantoin raw materials, heating at 85 deg.C for 30min, and stirring at 50r/min for 10min to obtain phase A raw material;
2) cooling the phase A raw material to below 40 ℃, adding an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, an oat extract and a preservative into the phase A raw material, stirring the mixture for 5min at a speed of 70r/min, cooling the mixture to below 35 ℃, and subpackaging the mixture to obtain the anti-aging wrinkle-lightening essence.
The antiseptic is selected from polyols such as hexanediol and phenoxyethanol.
Compared with the prior art, the invention has the beneficial effects that:
1) the anti-aging composition provided by the invention simultaneously contains fermentation products such as hydroxypropyl tetrahydropyrane triol, cracked yeast fermentation product lysate, lactobacillus fermentation filtrate, yeast/rice fermentation product filtrate and the like, the action mechanisms of the fermentation products are complementary, and the anti-aging and wrinkle-removing effects of the anti-aging composition are better by combined application.
2) The anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product is simple in preparation method, production working hours are saved, the stability of active ingredients can be kept in the preparation process, and the composition can also have obvious anti-aging and wrinkle-removing effects.
3) The invention is safe and non-irritant, and is easy to be added into the formulation systems of various formulations of cosmetics, thereby having important practical significance and wide market prospect.
Drawings
FIG. 1 is a schematic diagram of the fermentation of lactic acid bacteria in an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product provided by the invention.
Fig. 2 is a graph showing the texture improvement effect of the anti-aging wrinkle-lightening essence obtained in example 1 of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
The invention discloses an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, which is prepared by taking hydroxypropyl tetrahydropyrane triol, the fermentation product composition (a lysate of a yeast dehiscent fermentation product, a lactic acid bacteria fermentation filtrate, a yeast/rice fermentation product filtrate) and butanediol as raw materials and combining the raw materials according to a proper weight ratio.
The technical effects of the raw material components are described below.
(iii) hydroxypropyl Tetrahydropyranetriol
Hydroxypropyl tetrahydropyrane triol, a xylose derivative derived from western european beech wood, was an anti-aging active ingredient first developed by the lancome laboratory, has the efficacy of promoting the synthesis of collagen and glycosaminoglycan, and helps the dermis maintain elasticity by targeting at the junction DEJ of the epidermis and the dermis.
② two split yeast fermentation product lysate
The lysate of the yeast fermentation product of the bifidus is cultured, inactivated and decomposed by bifidobacterium to obtain metabolites, cytoplasmic fragments, cell wall components and polysaccharide complexes, has strong immunosuppressive activity, can promote DNA repair, help prevent photoaging of epidermis and dermis, can also generate small molecules which comprise vitamin B group, minerals, amino acids and the like and are beneficial to skin care, strengthen metabolism of stratum corneum, capture free radicals, inhibit peroxidation of lipid and have the function of resisting aging.
③ lactic acid bacteria fermentation filtrate
The lactobacillus fermentation filtrate contains thalli and all active ingredients synthesized in the fermentation process, contains peptidoglycan, teichoic acid, protein, phospholipid, sterol, fatty acid, various enzymes, peptide, amino acid, nucleotide, exopolysaccharide and the like, can accelerate the growth of epidermis, maintain the activity and health of epidermal cells, improve the cell cohesion, repair the barrier function of skin, inhibit bacterial infection, stimulate the shedding of aged cells, promote the metabolism of melanin accumulated on the horny layer, improve rough skin and have good anti-aging effect. The fermentation principle of lactic acid bacteria is shown in FIG. 1.
Fourthly, the filtrate of the yeast/rice fermentation product
The yeast/rice fermentation product filtrate is prepared by fermenting rice with yeast, synthesizing metabolites, obtaining raw materials beneficial to skin, such as polysaccharide, protein, organic acid, etc., maintaining skin moisture, scavenging free radicals, renewing skin cells, resisting skin inflammation, reducing cell injury, providing nutrients, and maintaining skin health.
The anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product has the effects of promoting collagen synthesis, removing free radicals, accelerating skin renewal and repairing skin barriers by virtue of different action mechanisms of the components, enhancing the permeability of the anti-aging composition with the aid of humectants such as butanediol and the like and realizing the synergistic effect of the components.
In the following examples, the unit of parts by weight may be g or kg. All the raw material components of the invention are commercial products. Hydroxypropyl tetrahydropyran triol is available from shanghai kejin science and technology ltd; the secondary split yeast fermentation lysate, lactobacillus fermentation filtrate, yeast/rice fermentation filtrate were all purchased from CLR, germany; oat extract was purchased from demi.
The lysate of the yeast fermentation product of the bifidus is obtained by culturing, inactivating and decomposing the bifidobacteria to obtain metabolites, cytoplasmic fragments, cell wall components and polysaccharide complexes.
The lactobacillus fermentation filtrate and the yeast/rice fermentation product filtrate can be respectively prepared by carrying out propagation culture on lactobacillus strains and yeast strains in a seed culture medium, fermenting in a fermentation culture medium to obtain an initial system, and carrying out centrifugation, emulsification and inactivation treatment on the initial system.
Example 1
The embodiment provides an anti-aging wrinkle-lightening essence which comprises the following raw material components in parts by weight:
57.6 parts by weight of deionized water;
40 parts by weight of an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product;
0.1 part by weight of sodium hyaluronate;
0.1 part by weight of xanthan gum;
0.2 part by weight of allantoin;
1 part by weight of oat extract;
1 part by weight of hexanediol;
the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products comprises the following raw material components:
10 parts by weight of hydroxypropyl tetrahydropyrane triol;
5 parts by weight of a split yeast fermentation product lysate;
5 parts of lactobacillus fermentation filtrate;
10 parts by weight of yeast/rice fermentation product filtrate;
10 parts of butanediol;
60 parts of deionized water;
the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products is prepared by the following method:
1) dissolving hydroxypropyl tetrahydropyrane triol and butanediol in deionized water, and uniformly stirring at the stirring speed of 50r/min to prepare a hydroxypropyl tetrahydropyrane triol solution, namely a component A;
2) and sequentially adding the lysate of the yeast fermentation product of the second split, the lactic acid bacteria fermentation filtrate, the yeast/rice fermentation product filtrate and the component A into the deionized water, and uniformly stirring at the stirring speed of 40r/min to obtain the anti-aging hydroxypropyl tetrahydropyrane triol and the fermentation product composition.
The preparation method of the anti-aging wrinkle-lightening essence comprises the following steps:
1) mixing deionized water, sodium hyaluronate, xanthan gum and allantoin raw materials, heating at 85 deg.C for 30min, and stirring at 50r/min for 10min to obtain phase A raw material;
2) cooling the phase A raw material to below 40 ℃, adding an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, an oat extract and a preservative into the phase A raw material, stirring the mixture for 5min at a speed of 70r/min, cooling the mixture to below 35 ℃, and subpackaging the mixture to obtain the anti-aging wrinkle-lightening essence.
Example 2
The embodiment provides an anti-aging wrinkle-lightening essence which comprises the following raw material components in parts by weight:
67.6 parts by weight of deionized water;
30 parts by weight of an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product;
0.1 part by weight of sodium hyaluronate;
0.1 part by weight of xanthan gum;
0.2 part by weight of allantoin;
1 part by weight of oat extract;
1 part by weight of phenoxyethanol;
the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products comprises the following raw material components:
10 parts by weight of hydroxypropyl tetrahydropyrane triol;
5 parts by weight of a split yeast fermentation product lysate;
5 parts of lactobacillus fermentation filtrate;
10 parts by weight of yeast/rice fermentation product filtrate;
10 parts of butanediol;
60 parts of deionized water;
the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products is prepared by the following method:
1) dissolving hydroxypropyl tetrahydropyrane triol and butanediol in deionized water, and uniformly stirring at the stirring speed of 50r/min to prepare a hydroxypropyl tetrahydropyrane triol solution, namely a component A;
2) adding the lysate of the yeast fermentation product of the second split, the lactobacillus fermentation filtrate, the yeast/rice fermentation product filtrate and the component A into deionized water in sequence, and stirring uniformly at the stirring speed of 40r/min to obtain the anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product.
The preparation method of the anti-aging wrinkle-lightening essence comprises the following steps:
1) mixing deionized water, sodium hyaluronate, xanthan gum and allantoin raw materials, heating at 85 deg.C for 30min, and stirring at 50r/min for 10min to obtain phase A raw material;
2) cooling the phase A raw material to below 40 ℃, adding an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, an oat extract and a preservative into the phase A raw material, stirring the mixture for 5min at a speed of 70r/min, cooling the mixture to below 35 ℃, and subpackaging the mixture to obtain the anti-aging wrinkle-lightening essence.
Example 3
The embodiment provides an anti-aging wrinkle-lightening essence which comprises the following raw material components in parts by weight:
87.6 parts by weight of deionized water;
10 parts by weight of an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product;
0.1 part by weight of sodium hyaluronate;
0.1 part by weight of xanthan gum;
0.2 part by weight of allantoin;
1 part by weight of oat extract;
1 part by weight of hexanediol;
the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products comprises the following raw material components:
10 parts by weight of hydroxypropyl tetrahydropyrane triol;
5 parts by weight of a split yeast fermentation product lysate;
5 parts of lactobacillus fermentation filtrate;
10 parts by weight of yeast/rice fermentation product filtrate;
10 parts of butanediol;
60 parts of deionized water;
the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products is prepared by the following method:
1) dissolving hydroxypropyl tetrahydropyrane triol and butanediol in deionized water, and uniformly stirring at the stirring speed of 50r/min to prepare a hydroxypropyl tetrahydropyrane triol solution, namely a component A;
2) adding the lysate of the yeast fermentation product of the second split, the lactobacillus fermentation filtrate, the yeast/rice fermentation product filtrate and the component A into deionized water in sequence, and stirring uniformly at the stirring speed of 40r/min to obtain the anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product.
The preparation method of the anti-aging wrinkle-lightening essence comprises the following steps:
1) mixing deionized water, sodium hyaluronate, xanthan gum and allantoin raw materials, heating at 85 deg.C for 30min, and stirring at 50r/min for 10min to obtain phase A raw material;
2) cooling the phase A raw material to below 40 ℃, adding an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, an oat extract and a preservative into the phase A raw material, stirring the mixture for 5min at a speed of 70r/min, cooling the mixture to below 35 ℃, and subpackaging the mixture to obtain the anti-aging wrinkle-lightening essence.
Blank example 1
The blank example 1 is different from the example 1 only in the raw material components of the anti-aging and wrinkle-lightening essence, and the anti-aging and wrinkle-lightening essence in the blank example 1 does not contain the anti-aging composition of hydroxypropyl tetrahydropyrane triol and fermentation product, and the other operations are the same as the example 1.
Test example for Effect verification
First, safety test-Patch test
Test subjects: the anti-aging wrinkle-lightening essence obtained in examples 1-3 and the anti-aging wrinkle-lightening essence obtained in blank example 1.
The number of the tested persons is as follows: 150, male and female halves, and the age between 20 and 55 years, all meet the subject criteria.
The test process comprises the following steps: the test population of 150 persons meeting the standard of the test subjects is randomly divided into 5 groups, and the groups respectively correspond to the anti-aging wrinkle essence obtained in the examples 1-3, the anti-aging wrinkle essence obtained in the blank example 1 and a control group of 30 persons in each group of the test subjects; respectively placing the anti-aging and wrinkle-lightening essence in the test object into the small chambers of the spot tester, wherein the dosage is about 0.020mL-0.025mL, and no substance is placed in the control holes; the spot tester with the test substance is applied to the back or the forearm curvature of the subject with hypoallergenic tape (manufacturer: Shanghai medical apparatus and instruments (group) Co., Ltd., hygienic materials factory, product number of spot test tape: 09000251116), and is applied to the skin with palm gently for 24 h; skin reactions were observed at 30min, 24h, and 48h after removal of the test article blotter according to the criteria shown in table 1 and the observations were recorded, with the ranking criteria shown in table 1 and the test results shown in table 2.
TABLE 1 skin occlusion Patch test skin response grading Standard
TABLE 2 test results of the skin patches on human body of examples 1-3 and blank example 1 of the present invention
As can be seen from Table 2, the anti-aging wrinkle-lightening essence obtained in examples 1-3 and blank example 1 of the present invention is non-irritating to the skin.
Second, efficacy test
Test subjects: the antiaging composition of example 1 contains hydroxypropyl tetrahydropyrane triol, a fermentation product. The anti-aging wrinkle-lightening essence obtained in examples 1-3 and the anti-aging wrinkle-lightening essence obtained in blank example 1.
1) Percent oxygen radical inhibition test
The photon energy of ultraviolet rays is absorbed by atoms or molecules of cells, causing the state of the electronic energy level of the atoms to change, generating a large amount of free radicals, which can hinder the normal development of the cells, interfere with the metabolism of the cells, destroy mitochondria in the cells, and the like.
The test method comprises the following steps: using Organotypical skin model
The skin model is pretreated by the anti-aging wrinkle-lightening essence of the invention, Ve and Vc are control groups, and ultraviolet irradiation with different intensities (0-30 mJ/cm)2UVB intensity), the percent oxygen radical inhibition was measured and the results are shown in table 3.
TABLE 3 test results
As can be seen from table 3, the anti-aging wrinkle-lightening essence obtained in examples 1 to 3 of the present invention can effectively remove oxygen radicals caused by ultraviolet rays; the anti-aging and wrinkle-reducing essence obtained in blank example 1 has a weak ability of removing oxygen radicals caused by ultraviolet rays. The anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation products can effectively eliminate oxygen free radicals caused by ultraviolet rays.
2) Experiment for promoting proliferation of human keratinocyte (hacat cell)
When people study body aging and skin aging, people mostly stress the aging of skin fibroblasts. In recent years, it has been gradually recognized that keratinocytes also play a very important role in skin aging. With age, skin aging is manifested by a slowing of epidermal turnover, a diminished barrier function, and a diminished keratinocyte viability.
The test method comprises the following steps: establishing a keratinocyte in-vitro cytology model, culturing Hacat cells in a 24-well plate, adding 0.1 percent, 0.3 percent and 0.5 percent of the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and polypeptide protein in example 1, and adding hoechst3342 nucleic acid dye after 24 hours. Incubate for 15 minutes and then take pictures. The results are shown in Table 4.
TABLE 4 test results
As can be seen from Table 4, the anti-aging composition containing 0.1%, 0.3% and 0.5% of hydroxypropyl tetrahydropyrane triol and fermentation product obtained in example 1 of the present invention can effectively promote the value increase of hacat cell and accelerate the skin renewal speed.
Third, synergistic Experimental example
Comparative examples 1 to 12
The anti-aging wrinkle-lightening essence comprises the following raw materials in different proportions, as shown in table 5.
Table 5 shows the raw material composition ratio (wt%)
The preparation process was as described in example 1 above.
The anti-wrinkle effect test was performed on example 1 and comparative examples 1 to 12, and the test results after one month are shown in table 4.
TABLE 6 test results
| Group of | Comparative example 1 | Comparative example 2 | Comparative example 3 | Comparative example 4 | Comparative example 5 |
| Wrinkle area reduction value (%) | 6.8 | 5.4 | 4.5 | 6.0 | 13.5 |
| Group of | Comparative example 6 | Comparative example 7 | Comparative example 8 | Comparative example 9 | Comparative example 10 |
| Wrinkle area reduction value (%) | 10.1 | 11.0 | 15.1 | 24.7 | 28.4 |
| Group of | Comparative example 11 | Comparative example 12 | Example 1 | ||
| Wrinkle area reduction value (%) | 27.9 | 23.6 | 35.1 |
As can be seen from the experimental data in table 6, the anti-wrinkle effects are ranked as example 1> comparative example 9, 10, 11, 12> comparative example 5, 6, 7, 8> comparative example 1, 2, 3, 4, and it is demonstrated that the anti-aging composition containing hydroxypropyl tetrahydropyrane triol and fermentation product has better anti-aging effect than the combination of only one, two or three components through the synergistic effect between the components.
Third, human body trial evaluation experiment
Test subjects: the anti-aging wrinkle-lightening essence obtained in examples 1-3 and the anti-aging wrinkle-lightening essence obtained in blank example 1. The essence is adopted for testing: the test persons are 100 persons, each group of 25 persons is numbered 1-25, and the test persons are used for 2 times in 1 day for 3 weeks continuously. Filling a trial effect evaluation table according to the sensory evaluation (a volunteer evaluation scoring system is adopted, wherein the highest score is 2 to indicate satisfaction, the highest score is 1 to indicate generality, and the highest score is 0 to indicate dissatisfaction). Wrinkle, elasticity, firmness, and repair sensitivity were measured using a skin detector, specifically a Visia skin detector. Experimental results statistics of human trial evaluation results are shown in table 7.
TABLE 7 test results
As can be seen from the test data in table 7, the anti-wrinkle essence obtained in examples 1 to 3 of the present invention can effectively reduce wrinkles, improve skin elasticity and firmness, and repair skin barriers, and has an effect superior to that of the anti-wrinkle essence of blank example 1. The texture improvement effect of the anti-wrinkle essence obtained in example 1 is shown in fig. 2. The texture is an index for measuring the evenness and smoothness of the skin color, the left and right images are comparison images before and after the anti-aging and wrinkle-lightening essence is used, and the skin is smoother after the anti-aging and wrinkle-lightening essence is used, so that the fine lines of the face are improved.
In conclusion, the anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product can promote collagen synthesis, remove free radicals, accelerate skin renewal, repair skin barriers and fade skin wrinkles.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. An anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product is characterized in that: the anti-aging composition comprises the following raw material components in parts by weight:
0.1-20 parts by weight of hydroxypropyl tetrahydropyrane triol;
0.1-20 parts by weight of a split yeast fermentation product lysate;
0.1-20 parts of lactobacillus fermentation filtrate;
1-30 parts by weight of yeast/rice fermentation product filtrate;
1-20 parts of butanediol;
20-70 parts of deionized water.
2. The anti-aging composition comprising hydroxypropyl tetrahydropyrane triol, fermentation product according to claim 1, wherein: the anti-aging composition comprises the following raw material components in parts by weight:
0.1-10 parts by weight of hydroxypropyl tetrahydropyrane triol;
0.5-10 parts by weight of a split yeast fermentation product lysate;
0.2-10 parts of lactobacillus fermentation filtrate;
1-20 parts by weight of yeast/rice fermentation product filtrate;
5-15 parts of butanediol;
35-60 parts of deionized water.
3. The method for preparing an antiaging composition containing hydroxypropyl tetrahydropyrane triol and fermentation product according to claim 1 or 2, characterized by comprising the steps of:
1) dissolving hydroxypropyl tetrahydropyrane triol and butanediol in deionized water, and uniformly stirring to prepare a hydroxypropyl tetrahydropyrane triol solution, namely a component A;
2) adding the lysate of the yeast fermentation product of the second split, the lactic acid bacteria fermentation filtrate, the yeast/rice fermentation product filtrate and the component A into deionized water in sequence, and stirring uniformly to obtain the anti-aging composition containing the hydroxypropyl tetrahydropyrane triol and the fermentation product.
4. The method of claim 3, wherein: in the step 1), the stirring speed is 20-80r/min, and in the step 2), the stirring speed is 30-100 r/min.
5. The method of claim 3, wherein: in the step 2), the mass ratio of the total mass of the 4 raw materials of the hydroxypropyl tetrahydropyrane triol, the cracked yeast fermentation product lysate, the lactobacillus fermentation filtrate and the yeast/rice fermentation product filtrate to the water is 1: 0.5-2.5.
6. The method of claim 5, wherein: in the step 2), the mass ratio of the total mass of the 4 raw materials of the hydroxypropyl tetrahydropyrane triol, the cracked yeast fermentation product lysate, the lactobacillus fermentation filtrate and the yeast/rice fermentation product filtrate to the water is 1: 2.
7. Use of an anti-aging composition comprising hydroxypropyl tetrahydropyrane triol-containing fermentation product according to claim 1 or 2 in skin care products, characterized in that: the skin care product comprises 10-40% of the anti-aging composition by total weight of the skin care product; and 60-90% of conventional auxiliary materials in the field of skin care products.
8. The use of a hydroxypropyl tetrahydropyrane triol, fermentation product-containing anti-aging composition according to claim 7 in a skin care product, wherein: the conventional auxiliary materials comprise a surfactant, a thickening agent, a conditioning agent, a humectant, a preservative, a chelating agent, essence and deionized water.
9. The use of a hydroxypropyl tetrahydropyrane triol, fermentation product-containing anti-aging composition according to claim 7 in a skin care product, wherein:
the skin care product is prepared into various dosage forms of toner, smoothing toner, firming toner, nourishing cream, massage cream, essence, eye cream, eye essence, cleansing cream, cleansing foam, cleansing water, facial mask, pressed powder, body lotion, body cream, body oil, body lotion and body essence.
10. The use of a hydroxypropyl tetrahydropyrane triol, fermentation product-containing anti-aging composition according to claim 7 in a skin care product, wherein:
the skin care product is prepared into anti-aging wrinkle-lightening essence which comprises the following raw material components:
57.6 to 87.6 parts by weight of deionized water;
10-40 parts by weight of an anti-aging compound containing hydroxypropyl tetrahydropyrane triol and a fermentation product group;
the anti-aging wrinkle-lightening essence is prepared by the following steps:
1) mixing deionized water, sodium hyaluronate, xanthan gum and allantoin raw materials, heating at 85 deg.C for 30min, and stirring at 50r/min for 10min to obtain phase A raw material;
2) cooling the phase A raw material to below 40 ℃, adding an anti-aging composition containing hydroxypropyl tetrahydropyrane triol and a fermentation product, an oat extract and a preservative into the phase A raw material, stirring the mixture for 5min at a speed of 70r/min, cooling the mixture to below 35 ℃, and subpackaging the mixture to obtain the anti-aging wrinkle-lightening essence.
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| CN114469843A (en) * | 2022-02-28 | 2022-05-13 | 广州环亚化妆品科技股份有限公司 | Composition with soothing and repairing effects and preparation method and application thereof |
| CN115006295A (en) * | 2022-07-06 | 2022-09-06 | 上海云未生物科技有限公司 | Anti-aging composition, preparation method and application thereof in preparation of anti-aging cosmetics |
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| CN115887259A (en) * | 2022-11-25 | 2023-04-04 | 上海臻臣化妆品有限公司 | Anti-inflammatory and anti-aging composition, anti-inflammatory and anti-aging essence and preparation method thereof |
| CN116115549A (en) * | 2023-01-06 | 2023-05-16 | 北京岳达生物科技有限公司 | Cosmetic composition and preparation method and application thereof |
| CN116077413A (en) * | 2023-03-06 | 2023-05-09 | 广州优理氏生物科技有限公司 | Composition for resisting oxidation and aging and application thereof as well as essence |
| CN116077413B (en) * | 2023-03-06 | 2023-06-06 | 广州优理氏生物科技有限公司 | Composition for resisting oxidation and aging and application thereof as well as essence |
| CN117180121A (en) * | 2023-10-18 | 2023-12-08 | 广州品域美妆创新科技有限公司 | Anti-wrinkle and light-grain composition containing vitrine and application thereof |
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