CN109464373A - A kind of antiallergic facial treatment mask - Google Patents
A kind of antiallergic facial treatment mask Download PDFInfo
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- CN109464373A CN109464373A CN201811386042.8A CN201811386042A CN109464373A CN 109464373 A CN109464373 A CN 109464373A CN 201811386042 A CN201811386042 A CN 201811386042A CN 109464373 A CN109464373 A CN 109464373A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/445—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
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Abstract
The present invention provides a kind of antiallergic facial treatment mask, mainly contain the component of following weight percentage: false illiciumverum leaf extract 0.5-3%, hydroxy phenylpropionyl amine benzoic acid 0.1-0.2%, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.1-2.0%, tetrahydro methylpyrimidine carboxylic acid 0.1-1.0%.Antiallergic facial treatment mask of the present invention can reach deep layer and releive, and be effective against injury of the external environment to skin, improve cutaneous immunisation power, strengthen skin barrier, repair sensitive skin.The preceding temple laver amylose of Abelmoschus esculentus berry extract, avenabeta glucosan, water, biological carbohydrate gum -4, Cer NP can also be added in the antiallergic facial treatment mask, by the proportion and compounding of science, moisturizing therein, antiallergic effective component coordinated, allow product effect to play more preferably.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of antiallergic facial treatment mask.
Background technique
With the high speed development of science and technology, the nature for stepping up and liking to be beautiful of living standards of the people, people increasingly pay attention to
The health status of autologous skin.And since climate change is big, air pollution increasingly aggravates, stress increases and cosmetics type
It is just gradually risen with factors, the incidences of sensitive such as the diversity and complexity of ingredient, people are to sensitive
Perception rate and attention rate are also gradually increasing.Show that the world is each according to the data that " Chinese sensitive specialist common recognition " discloses
The incidence of state's sensitive approximately as: Europe be 25.4%~89.9%, Australia is about 50%.Women disease incidence is generally high
In male, America women is 22.3%~50.9%, and Asia women is 40%~55.98%, 54.65% Chinese women self confirmation
Having has a sensitive skin in skin sensitivity problem, that is, every 2 people, 70% tender subject occurs in season, 78%
People needs to take more time with energy to nurse sensitive skin.
Sensitive (SensitiveSkin, SS) is a kind of skin condition that height does not tolerate, vulnerable to it is various because
The stimulation of element and generate the subjective symptoms such as shouting pain, scorching hot, tight, itch, skin appearance it is normal or with slight drying furfur,
The objective signs such as telangiectasis and erythema.International sensitive skin Consensus of experts, sensitive refer to for conventional stimulation (just
There is not abnormal sensory in normal state) there is a kind of uncomfortable synthesis for feeling and (including: shouting pain, burn, pain, itch and tingle)
Sign；The sense of discomfort cannot explain that skin appearance can be normally or with erythema by any skin disease correlation skin lesion；Sensitive
It can be involved any position of whole body, it is especially facial.80% or more involves face, and 44% involves scalp.Domestic sensitive expert
Common recognition emphasizes that sensitive is a kind of inferior health skin condition, has high sensibility, poor resistance and high response three big special
Point.
Research is thought at present, and sensitive is that a kind of skin barrier-neural blood vessel-immune inflammation that involves is answered
Miscellaneous process.It is interior because and the interaction of external cause under, skin barrier function is impaired, cause sensory nerve input signal to increase,
Cause skin to enhance the reactivity of environmental stimuli, causes cutaneous immunisation inflammatory reaction.
Sensitive skin is widely considered to be the immunity degradation that skin barrier function is damaged and makes skin, cutin shape by academia
Cause cuticula thinning at the reduction of cell, transepidermal water loss rate (trans epidermal water loss, TEWL) increases,
Water content of stratum corneum reduces, and makes skin reactivity with higher, and the barrier function for eventually leading to skin is excessively weak, can not
Resist environmental stimuli.Then the nerve fibre of skin is excessively excited due to being often subject to environmental stimuli, to be easy to generate general
It is red, fever, itch, shouting pain, the generation of the discomfort phenomenon such as erythema.Traditional moisturizing, whitening, it is anti-ageing, moisten and other effects cosmetics
It is much unable to satisfy the demand of " sensitive flesh " consumer.
Summary of the invention
Based on this, the purpose of the present invention is to provide a kind of antiallergic facial treatment mask, and ingredient is mild, stable system, affine flesh
Skin, easy osmotic absorption, skin sense is soft and moist salubrious, and not sticky, with moisturizing, water lock, water storage are resisted external environment and invaded skin
The effect of evil improves immunity, repairs impaired skin and enhancing skin barrier, to establish healthy skin barrier, reaches reparation
Sensitive skin is general red, fever, itch, shouting pain, the discomfort phenomenon such as erythema, moreover it is possible to and so that skin is kept comfortable, pleasant, it is glossy, have
The health status of elasticity.
To achieve the goals above, the specific technical solution of the present invention is as follows:
A kind of antiallergic facial treatment mask, mainly contains the component of following weight percentage:
False illiciumverum (TASMANNIA LANCEOLATA) leaf extract 0.5-3%,
Hydroxy phenylpropionyl amine benzoic acid 0.1-0.2%,
Bacillus acidi lactici/soya-bean milk tunning filtrate 0.1-2.0%,
Tetrahydro methylpyrimidine carboxylic acid 0.1-1.0%.
In wherein some embodiments, the antiallergic facial treatment mask also contains the component of following weight percentage:
Abelmoschus esculentus (HIBISCUS ESCULENTUS) berry extract 0.1-1%,
Oat (AVENA SATIVA) beta glucan 0.2-2.0%,
The preceding temple seaweed of water (APHANOTHECE SACRUM) polysaccharide 0.1-0.5%,
Biological -4 0.1-1% of carbohydrate gum,
Cer NP 0.1-0.5%.
In wherein some embodiments, the antiallergic facial treatment mask also contains the component of following weight percentage:
Polyalcohol 4.5-13%,
Preservative 0.6-0.75%,
Rheology modifiers 0.15-0.45%,
PH adjusting agent 0.03-0.12%.
Polyalcohol of the present invention can be glycerol, propylene glycol, 1,3- propylene glycol, butanediol, pentanediol, hexylene glycol, mountain
Pears alcohol, ethyl alcohol, polyethylene glycol-8, polyethylene glycol -32, dipropylene glycol, diglycerol, glycerin polyether -26, Natrulon H-10, gather it is sweet
One or more kinds of mixing of oil -8.
In wherein some embodiments, the polyalcohol is by glycerol, 1,3-PD, glycerin polyether -26, propylene glycol group
Mass ratio at, the glycerol, 1,3-PD, glycerin polyether -26, propylene glycol is (0.5-3): (3-7): (1-3):
(0.004-0.02).
In wherein some embodiments, the preservative is the mixing of parahydroxyacet-ophenone and E59, described to hydroxyl
Acetophenone, E59 mass ratio be (0.2-0.3): (0.4-0.45).
Rheology modifiers of the present invention can be xanthan gum, hydroxyethyl cellulose, carbomer, carbomer sodium, propylene
Sour (ester) analog copolymer, polyvinylpyrrolidone, aluminum magnesium silicate, mosanom, acrylic acid (ester) class/C10-30 alkylol acrylamide acid
Ester cross-linked polymer, sodium metasilicate magnesium lithium, polyacrylate cross-linked polymer -6, Sodium Polyacrylate graft starch, hydroxypropyl methyl
Cellulose, polyethylene glycol -90M, ammonium acryloyldime-thyltaurate/VP copolymer, acrylic acid (ester) class/docosyl alcohol polyethers -25
Methacrylate copolymer, Sodium Polyacrylate, gellan gum, pectin, Sodium Hyaluronate, polyglutamic acid sodium, carragheen, locust bean
Glue, dehydroxanthan, hydrolysis pyrenomycetes (SCLEROTIUM ROLFSSII) glue, pyrenomycetes (SCLEROTIUM ROLFSSII)
One kind of glue, tremella (TREMELLA FUCIFORMIS) fruiting body extract, Chondrus crispus (CHONDRUS CRISPUS) powder
Or more than one mixing.
In wherein some embodiments, the rheology modifiers are Sodium Polyacrylate graft starch and acrylic acid (ester)
The mixing of class/C10-30 alkylol acrylamide acid esters cross-linked polymer, the Sodium Polyacrylate graft starch, acrylic acid (ester) class/
C10-30 alkylol acrylamide acid esters cross-linked polymer mass ratio is (0.1-0.25): (0.05-0.2).
PH adjusting agent of the present invention can be triethanolamine, arginine, aminomethyl propanol, tromethamine, hydrogen-oxygen
Change one or more kinds of mixing of potassium, sodium hydroxide.
In wherein some embodiments, the pH adjusting agent is aminomethyl propanol.
In wherein some embodiments, the antiallergic facial treatment mask also contains the component of following weight percentage:
Blue chamomile essential oil 0.001-0.005%.
In wherein some embodiments, the antiallergic facial treatment mask also contains the component of following weight percentage:
EDTA disodium 0.02-0.05%,
Polyglutamic acid 0.02-0.05%,
Allantoin 0.05-0.2%,
Hydrolecithin 0.2-0.5%,
Bai Chihua (LIMNANTHES ALBA) seed oil 0.1-0.3%,
Isononyl isononanoate 0.1-0.5%,
PPG-10 methyl ether 0.4-1%,
- 9 0.005-0.025% of C12-13 Pareth.
The present invention has the advantage that and the utility model has the advantages that
(1) antiallergic facial treatment mask of the present invention largely test and experience by inventor, by by vacation illiciumverum (TASMANNIA
LANCEOLATA) leaf extract, hydroxy phenylpropionyl amine benzoic acid, Bacillus acidi lactici/soya-bean milk tunning filtrate, tetrahydro methylpyrimidine
Four kinds of antiallergic active constituent scientific matchings of carboxylic acid, can reach deep layer and releive, and be effective against injury of the external environment to skin, improve
Cutaneous immunisation power strengthens skin barrier, repairs sensitive skin；It is prior to be suitable for dry water shortage skin and skin is protected self
The weaker crowd of shield ability, using after product, without any allergic phenomena, and after a period of use, skin is obviously glossy, skin
Skin is healthier, effectively solves the skin problem of sensitive skin special population.
(2) antiallergic facial treatment mask of the present invention is by being added Abelmoschus esculentus (HIBISCUS ESCULENTUS) berry extract, swallow
Wheat (AVENA SATIVA) beta glucan, the preceding temple seaweed of water (APHANOTHECE SACRUM) polysaccharide, biological carbohydrate gum -4, neural acyl
Amine 3, by multiple single active ingredients by the proportion and compounding of science, moisturizing therein, the collaboration of antiallergic effective component are matched
Close, allow product effect play more preferably, and make antiallergic facial treatment mask of the present invention reach can to skin moisturizing, water lock, water storage function
Effect, makes skin keep water to moisten for a long time, can resist extraneous infringement, and barrier function enhancing keeps comfortable, pleasant health status,
Solve fragile skin, sensitive skin special population malaise symptoms, maintain skin glossy, flexible.
(3) antiallergic facial treatment mask ingredient of the present invention is mild, does not add essence, adds the blue camomile essential oil of Bulgaria, not only
The fragrance of product pleasure is provided, also with bactericidal antiphlogistic, antihistamine and antiallergy, the effect of relieving stress.
(4) antiallergic facial treatment mask stable system of the present invention, affine skin, easy osmotic absorption, skin sense is soft and moist salubrious, does not glue
It is greasy, keep skin moist.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description.Embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Part material according to the present invention is described as follows:
Hydroxy phenylpropionyl amine benzoic acid of the present invention, manufacturer: German moral it is fragrant, group is divided into butanediol, 1,2- penta 2
Alcohol, hydroxy phenylpropionyl amine benzoic acid.With antihistamine, anti-irritant, anti-oxidation efficacy.Block the generating process of cellular inflammation；Subtract
The generation of few inflammatory and immune response and the reaction of cutaneous nerve dermatitis.Erythema caused by histamine, oedema, scabies can be effectively suppressed
Itch.
False octagonal (TASMANNIA LANCEOLATA) leaf extract of the present invention, manufacturer: Australia
LUCAS MEYER.Its group is divided into glycerol, water, false octagonal (TASMANNIA LANCEOLATA) leaf extract, sodium benzoate.Come
From the rare active constituent in Australia, the pepper certain kind of berries fruit of this Monia specialty of tower extracts.It can instant sooth sensitive, reactive skin.Drop
Low tingling sensation inhibits proinflammatory factor excitation, reduces rapidly skin irritation and burning sensation.
Bacillus acidi lactici of the present invention/soya-bean milk tunning filtrate, trade name: difficult to understand graceful quick.Manufacturer: France is celestial graceful.
Its group is divided into water, Bacillus acidi lactici/soya-bean milk tunning filtrate, butanediol, 1,2- pentanediol.It with protection, releives, moisturizing is repaired
Multiple effect is to be belonged to by Japanese black soymilk by 16, totally 35 lactobacillus fermentations.Rich in multivitamin and albumen
Percutaneous permeability can be improved in matter, fermented ingredient, increases active constituent the effect of property.Bacillus acidi lactici will not kill harmful bacteria, but logical
The growth that environment inhibits harmful bacteria is crossed, skin faintly acid is maintained.Skin irritation sense caused by extraneous encroach on can be reduced immediately.Moment
Moisture content of skin is improved, skin elasticity is improved.Promote the synthesis of collagen and hyaluronic acid in fibroblast.
Tetrahydro methylpyrimidine carboxylic acid of the present invention, trade name: ECTOIN, manufacturer: German Bitop.With anti-
Skin barrier is repaired in inflammation, antiallergy, long-acting moisturizing, anti-aging, protects effect.ECTOIN had found in 1985 by people, source
A kind of microorganism from the salt lake Egyptian desert area Wadi EI Natrun.It is a kind of amino acid derivativges, one kind 100% is pure
Naturally, biotechnology fermentation and come ingredient of releiving.Eczema, dermatitis, allergic symptom it is demonstrated experimentally that ECTOIN can be used for releiving.
Inflammation can be reduced, skin barrier is enhanced, alleviates skin and itches.Repairing environment causes the damage of skin, reduce skin roughness and
The scales of skin that peel off.ECTOIN has effects that whole cell protection, and antipollution protection level is more than PM2.5, can anti-nano-scale particle；It is anti-light
Aging, ultraviolet (UVA/UVB), infrared, visible light full protection.
The preceding temple seaweed of water (APHANOTHECE SACRUM) polysaccharide of the present invention, manufacturer: big east chemical conversion industry meeting
Society Daito Kasei Kogyo, pale yellow viscous liquid, PH (10%, 25 DEG C): 5.0-7.0, viscosity (25 DEG C, 2#30r,
Brookfield) >=700mpa.s.The polysaccharide extracted from Shui Qiansi seaweed, molecular weight up to 29,000,000 dalton (29MDa),
It is one of the maximum natural molecule being currently known.Its group is divided into the preceding temple seaweed (APHANOTHECE of water, butanediol, water
SACRUM) polysaccharide.The preceding temple laver amylose of water is by glucose, mannose, galactolipin, fucose, glucuronic acid, galacturonic
11 kinds of acid, rhamnose, xylose, galactosamine, galactosamine, arabinose monosaccharide are constituted.Benefit with even more than hyaluronic acid
Waterpower forms gel moisture film in skin surface, and moisturizing more water lock reduces transepidermal water loss, improves dry skin quality.Reinforce skin defence
Function improves sensitive skin quality.The preceding temple laver amylose of water can evoke the antigen-reactive in epidermis and corium, it is possible to inhibit conduction scorching
The histamine releasing of disease property cell factor, cell of itching.There is inhibiting effect to the cell factor of allergic dermatitis, to macrophage
Inflammatory mRNA has direct inhibiting effect, has inhibiting effect to the epsilcapramin glucosides of giant cell release.Therefore have
Antiallergic, the effect of releiving.The effect of it also has enhancing skin elasticity, reduces skin wrinkle.Current research the result shows that, seaweed
Polysaccharide can effectively reduce the protein carbonyl as caused by PM2 .5.With being used in compounding for polyalcohol, can be used as formula helps cream
Agent.
Abelmoschus esculentus (HIBISCUS ESCULENTUS) berry extract of the present invention, manufacturer: Jiujiang Hua Han biology
Science and technology.By water, hydrolysis of pectin, Abelmoschus esculentus (HIBISCUS ESCULENTUS) berry extract, propylene glycol, double-PEG-15 first
Base ether dimethyl silicone polymer, Phenoxyethanol, Chlorphenesin composition.With good anti-oxidant, anti-aging and moistening effect, fruit
Grease and liposoluble vitamin E, good name plant hyaluronic acid, moistening effect rich in is extracted in fact to be mutually equal to hyaluronic acid
Beauty；
Oat (AVENA SATIVA) beta glucan of the present invention, manufacturer: Shanghai millet ground Industrial Co., Ltd..Its
Group is divided into water, glycerol, oat (AVENA SATIVA) beta glucan, Phenoxyethanol, Sensiva SC50.With long-term efficient
Moisturizing is releived, anti-aging, wrinkle resistance.Its own unique film forming characteristics can assign the appearance of skin smooth, such as silk
Moisten smooth sense of touch.Avenabeta glucosan can also significantly improve the immune function of skin, and maintenance skin damage barrier improves
Skin resists the ability of environmental stimuli, promotes wound healing, desalinates scar pigmentation.Tightening and softening that can be instant be tiny
Wrinkle improves skin firmness and elasticity.
Biological polyoses glue -4 of the present invention, manufacturer: plain Lai Biya.It is to be obtained from natural plants by zymotechnique
Epithelium protective agent, containing acetyl collateralization L-fucose, 2-D- galactolipin and glucuronic acid repetitive unit macromolecule
Polymer.Capable of being formed in skin surface, there is the 3D film of strength protection effect can reduce ultraviolet light and the external world such as Second Skin
Pollute the injury to skin.Invisible antipollution shielding is formed in skin surface, protects cells from radiation injury, protection is thin
Born of the same parents fight extraneous various invasion.Ultraviolet light can be defendd, color spot, free radical are effective against.
Cer NP of the present invention, manufacturer: South Korea Dou Shan.It is sweet that its group is divided into Cer NP, caprylic/capric
Oily three esters, water, hydrolecithin, Polyoxyethylene Sorbitan Monooleate, 1,2- hexylene glycol, butanediol, cyclohexasiloxane, five poly dimethyl of ring
Siloxanes, EDTA disodium.Ceramide be lipoid between being present in the corneocyte on the outside of human skin main composition at
Dividing (> 50%) to play prevents moisture from distributing and having to outside stimulus the important function of safeguard function, carries protection skin and taste
Profit, the function of moisturizing.Cer NP ceramide is the latest generation moisturizer developed in recent years, is a kind of water-soluble rouge
Metallic substance, it is close with the structure of matter of keratoderma is constituted, and the water that can be penetrated into quickly in skin and cuticula combines,
A kind of reticular structure is formed, moisture is lockked.Ceramide is sufficient, and skin barrier function, skin emolliency degree, glossiness accordingly mention
It is high.And the symptoms such as dry skin, furfur, coarse can be improved；It helps cuticula to thicken, promotes the tolerance of entire skin, protect
Extraneous nuisance intrusion, avoids sensitive generation, and plays the role of repairing red capillary.There is reduction wrinkle simultaneously, increase skin bullet
The effect of property, delay skin aging.
1,3-PD of the present invention, manufacturer: Dupont.It is a kind of environment, skin-friendly type moisturizer, it is molten
Agent, thickener, plant extraction and diluent, carrier for active principle, the ingredient of natural anticorrosion system, safety temperature are restructured in agent, sense of touch
With, skin will not be caused stimulation and it is uncomfortable phenomena such as.
Sodium Polyacrylate graft starch of the present invention, manufacturer: Daito Kasei Kogyo Co., Ltd.Excellent rheology changes
Good dose, aqueous solution is not sticky, can form smooth gel.
Glycerin polyether -26 of the present invention, manufacturer: Nature chemical.It is a kind of efficient moisture-retention agent, belongs to
Nonionic surfactant-polyalcohol polyoxyethylene ether.Glycerin polyether -26 is the polyglycerine of 26 EO, 1% addition
The moistening effect of amount is better than 3% glycerol.Smooth, fine and smooth sense of touch, no greasy feeling can improve product in the viscous of leather hard
Soapy feeling.
Propylene glycol of the present invention, manufacturer: Korea S SKC.Belong to small molecule moisturizing ingredient, moisture can be stayed in cutin
Layer has moisturizing, Penetration enhancing effect.
Parahydroxyacet-ophenone of the present invention, manufacturer: fragrant, the white powder of German moral.With anti-oxidant and easypro
Slow multifunctional cosmetics ingredient, broad spectrum preservation ability can be used as the substitute of traditional preservatives, can promote various preservatives
Synergy has excellent stability in height PH and temperature range, has with various cosmetic compositions and packaging material good compatible
Property；Skin is not stimulated mildly；It is a kind of natural plant extracts, is naturally present in many plants.
E59 of the present invention, manufacturer: South Korea DNE.Its group is divided into propylene glycol, decoyl hydroximic acid, 1,2- hexylene glycol,
Glycerol caprylate.Decoyl hydroximic acid is a kind of ideal organic acid, has excellent antibacterial, bacteriostasis property at neutral ph,
It can be used for without chemical preservative formula system.Decoyl hydroximic acid is that acid do not have the organic of ionized state to neutral whole all holdings
Acid is best antibacterial organic acid.There is compatibility with most raw materials, not by the originals such as surfactant, protein in system
The influence of material, can and alcohols, the preservatives such as glycols compounding.
Sodium Polyacrylate graft starch of the present invention, manufacturer: Daito Kasei Kogyo Co., Ltd.Excellent rheology
Modifying agent, aqueous solution is not sticky, can form smooth gel；
Aminomethyl propanol of the present invention, manufacturer: ANGUS chemical company (subsidiary, Dow Chemical), pH value adjustment
Agent.
Indigo plant chamomile essential oil of the present invention, INCI golden yellow chamomiles (CHRYSANTHELLUM INDICUM) are extracted
Object, the place of production: Bulgaria, navy blue dense fluids have pure and fresh fragrance；There are also bactericidal antiphlogistic, antihistamine and anti-mistake
Quick, the effect of relieving stress, improves sensitive, fragile, dry skin；The fragrance of product pleasure is provided simultaneously.
EDTA disodium of the present invention, manufacturer: French Akzo Nobel AKZONOBEL.For chelating agent, chelating gold
Belong to ion, stablizes essence, anti-corrosion synergy.
Polyglutamic acid of the present invention, manufacturer: Dodge (Zhuhai) fine chemistry industry has efficient moisture-retention: can not only be
One of network of rivers film is formed in skin surface, is reduced scattering and disappearing for hydrone, can more be goed deep into internal layer, promotes natural moisturizing factor content,
To achieve the purpose that efficient moisturizing, and under agile conditioning, the water content of skin is made to reach full state；Slowly biology point
Xie Xing makes skin surface be not easy cooperating microorganisms.
Allantoin of the present invention, manufacturer: German moral it is fragrant.Have the function of moisturizing, anti-inflammatory and wound healing,
Cutin-softening mildly locks skin moisture, keeps skin water profit soft and smooth.
Hydrolecithin of the present invention, manufacturer: Nikko Chemicals Co., Ltd.It is the skin of people with hydrophilic ability
Skin and hair absorb and can promote the infiltration of other nutriments, and active constituent is stored in cuticula；There are emulsification, moisturizing function
Effect.
Bai Chihua (LIMNANTHES ALBA) seed of the present invention oil, manufacturer: U.S. ELEMENTIS (hamming this),
One of most stable of vegetable oil has extraordinary antioxygenic property, and can stablize other vegetable oil.It is formed and is locked in skin surface
Aqueous film, tight water lock point resists drying, while unfolding skin pattern, and deep layer repairs skin damage, promotes skin overall profile.
It assigns magnificent texture and will not be too greasy, absorbs rapidly, beautiful and smooth skin sense can be more assigned than other vegetable oil.
Isononyl isononanoate of the present invention, manufacturer: INTERMER ESTERS.A kind of excellent emollient ester, it is silky
Feel, the skin sense of the dry and comfortable softness of lightweight, clearly without greasy.There is fabulous intermiscibility with silicone oil, it can be with dimethicone with any
Ratio is miscible, and can obtain the mixture of stable transparent.
PPG-10 methyl ether of the present invention, manufacturer: U.S. LUBRIZOL.It is that a kind of natural glucose spreads out
Raw moisturizing ingredient, it is non-stimulated as mild as a dove, good gloss is brought for product, the rear sticky sense of skin can be significantly improved, together
When it or a kind of good antifreeze, be a kind of ideal cosmetic composition.
Pareth -9 C12-13 of the present invention, manufacturer: husky rope sasol.It is a efficient solubilizing agents, micro emulsion
Agent can increase the solubility of microsolubility or insoluble substance.
Glycerol of the present invention, manufacturer: Malaysia is polite.It is excellent moisturizer, there is replenishing water and preserving moisture, exquisiteness such as
Sliding, moisturizing, prevents from having dry skin coarse, antifreeze effect.
The present invention is made further to illustrate in detail below by embodiment 1-5, comparative example 1-4, is taken respectively with weight hundred
Divide the following raw material than counting: water, EDTA disodium, glycerol, 1,3- propylene glycol, Sodium Polyacrylate graft starch, acrylic acid (ester)
Class/C10-30 alkylol acrylamide acid esters cross-linked polymer, polyglutamic acid, allantoin, hydrolecithin, Bai Chihua
(LIMNANTHES ALBA) seed oil, isononyl isononanoate, PPG-10 methyl ether, glycerin polyether -26, Abelmoschus esculentus
(HIBISCUS ESCULENTUS) berry extract, aminomethyl propanol, parahydroxyacet-ophenone, E59, oat (AVENA SATIVA)
The preceding temple seaweed of beta glucan, water (APHANOTHECE SACRUM) polysaccharide, biological carbohydrate gum -4, Cer NP, false illiciumverum
(TASMANNIA LANCEOLATA) leaf extract, hydroxy phenylpropionyl amine benzoic acid, Bacillus acidi lactici/soya-bean milk tunning filtrate,
Tetrahydro methylpyrimidine carboxylic acid, blue chamomile essential oil, C12-13 Pareth -9, propylene glycol.Specific proportion is shown in Table 1.
Table 1: embodiment 1-5, comparative example 1-4 proportioning components table
The facial mask that Example 1-5, comparative example 1-4 are obtained does control test, carries out keratoderma moisture determination, human body skin
Skin patch test, lactic acid irritant test and hyaluronidase Inhibition test.
1, keratoderma water content is tested
Keratoderma water content reduces, percutaneous water loss increase shows that skin may be damaged, and the probability that allergy occurs increases,
It can be measured by German CK skinanalysis apparatus MAP580, water content of stratum corneum height, percutaneous water loss reduce expression skin skin screen
It is smaller to hinder the extent of damage, and then evaluates sample antiallergic effect more preferably.
Test method: selecting the volunteer of 180 skins close (heavier flush), be divided into 9 groups at random, point
Not Shi Yong embodiment 1-5, comparative example 1-4 facial mask, time of application facial mask is 15-20min, later cleaning face, after 2 hours
Facial situation is evaluated, the index of evaluation is keratoderma water content, percutaneous water loss TEWL, flush journey
Degree；Be specifically divided into 5 intensity grades, intensity grade be indicated with the integer of 0-4 (wherein 0=nothing, 1=light, 2=in；3=weight, 4=
It is extremely heavy), specific index can be found in the following table 2.
Table 2: grading index table
Test result: after facial mask spreads on volunteer's face 15-20 minutes, then cleaning face 2 as a child observed volunteer's face
Flush degree, test moisture content of skin and percutaneous water loss situation, then graded according to the intensity grade of table 2,
See Table 3 for details for concrete outcome:
Table 3: volunteer's skin
Data can be seen that the facial mask using the present invention program from upper table 3, and the facial water content of stratum corneum of volunteer obtains
It is obviously improved, illustrates that the facial mask of 1-5 of the embodiment of the present invention has good moisture-keeping efficacy, wherein the moisture-keeping efficacy of embodiment 3
It is optimal.
2, human skin patch test
Suitable subject is selected to carry out human skin patch, the reaction according to patch result observation sample to human skin
Degree, and skin allergy degree size is identified to result is for statistical analysis, and then evaluates sample antiallergic effect.
Test method: the subject of selection 270 fragile flesh, with enclosed patch test method, by embodiment 1-5 facial mask
Liquid, comparative example 1-4 facial mask liquid respectively take about 0.020-0.025ml to be respectively put into 9 spot tester cells, are pasted on subject's arm
Interior survey.Spot tester is removed after 24 hours, is gently wiped if any surplus products with wet paper handkerchief, respectively at 0.5 hour, 24 is small
When, 48 hours observation dermoreaction situations, by dermoreaction grade scale note in " cosmetics safety technical specification " (2015 editions)
Record is as a result, the number for occurring 1 grade of skin adverse reaction in 30 subjects is more than the people of 5 or 2 grades skin adverse reactions
Number more than 2 (number of 2 order reaction of deodorising product patch test is more than 5), or there are any 13 grades or 3 grades or more skins
When adverse reaction, determine that tested material has skin adverse reaction to human body.Specific index can be found in the following table 4.
Table 4: grading index table
Test result: it is pasted in subject's arm and surveys, spot tester is removed after 24 hours, respectively at 0.5 hour, 24 hours, 48
Hour observation dermoreaction situation.Evaluate this group of facial mask to the reaction condition of human skin according to patch result, then root
It grades according to the intensity grade of table 4, see Table 5 for details for concrete outcome:
5 volunteer's patch test tables of data (being observed after 48 hours) of table
It is quick to can be seen that antiallergic facial treatment mask antiallergic described in embodiment 1-5 for data from upper table 5, can significantly mitigate skin
Erythema, redness.It is efficient high, good antiallergic can be played the role of, wherein the antiallergic effect of embodiment 3 is optimal.
3, lactic acid irritant test
Lactic acid irritant test, lactic acid cause the tingling sensation of skin within a certain period of time, under a certain concentration.According to reduction shouting pain degree
To evaluate antiallergic effect.
Test method: 270 volunteers (women of the age at 18-60 years old), after cleaning two sides nasolabial groove with dry cotton pads.
10% lactic acid is applied to nasolabial groove and any one side face cheek (other side cheek is smeared domestic water and compared) at room temperature,
Induced skin is inflamed.After ten minutes, when testee feels shouting pain, embodiment is smeared at the position for smearing lactic acid respectively
The facial mask liquid of 1-5, reference examples 1-4.Testee is beaten 30 minutes, 1 hour, 24 hours respectively according to feeling of pain, with 4 point-scores
Point, it judges using shouting pain degree after antiallergic facial mask liquid and red and swollen situation.Specifically, being divided into 4 intensity grades, intensity grade 0-
3 integer be indicated (wherein 0=nothing, 1=light, 2=in；3=weight).Specific index can be found in the following table 6.
Table 6: grading index table
Test result: the number for occurring 1 grade of skin adverse reaction in 30 subjects is more than 5 or 2 grades skin adverse reactions
Number is more than 2, or when any 13 grades or 3 grades of appearance or more skin adverse reaction, determines that tested material has skin not to human body
Good reaction.Specific index can be found in the following table 7:
Table 7: volunteer's lactic acid prick test tables of data (being observed after 30 minutes)
It can be seen from the data in Table 7 that feeling of pain reduces 80-90%, erythema journey after facial mask 30 minutes of smearing embodiment 1-5
Degree is reduced, and it is optimal that wherein the facial mask of embodiment 3, which reduces skin irritation sense and red and swollen significant effect,.
Hyaluronidase 4. (Hyaluronidase, HAase) Inhibition test
Hyaluronidase is the anaphylactoid participant of I type, and hyaluronidase and inflammation, allergy have strong correlation, research report
The drug of various histamine release of mast cell is adjustable hyaluronidase activity, and some antiallergic drugs have high inhibition hyaluronidase
Activity, therefore inhibit hyaluronidase activity as the index of research anti-allergic effects.
Hyaluronic acid is that content is most in extracellular matrix, the maximum ingredient of proportion, has very strong water absorbing capacity
And adhesiveness, the secretion of controllable cell factor, growth, proliferation, migration and the differentiation of cell are influenced, thus maintaining skin water
Point and elasticity, wound healing and vascularization etc. during serve it is main.Hyaluronidase is the specificity of hyaluronic acid
Lyases inhibits the activity of hyaluronic acid to can guarantee the content and normal function of hyaluronic acid.Hyaluronidase Inhibition test
It is most typical antiallergic activity rating in-vitro method, using hyaluronic acid enzyme inhibition rate as the antiallergic activity of metrics evaluation substance,
The more big then antiallergic activity of hyaluronic acid enzyme inhibition rate is stronger.
The present invention uses Elson-Morgan improved method, to the facial mask liquid of embodiment 1-5, comparative example 1-4 to hyaluronic acid
The inhibiting rate of enzyme is tested, and specific test result is detailed in the following table 8:
Table 8: embodiment 1-5, comparative example 1-4 facial mask to hyaluronic acid enzyme inhibition rate tables of data
Facial mask of the invention can preferably inhibit the activity of hyaluronidase it can be seen from data in upper table 8, have good
Antiallergic effect wherein the antiallergic effect with embodiment 3 is good be optimal.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (9)
1. a kind of antiallergic facial treatment mask, it is characterised in that: mainly contain the component of following weight percentage:
False illiciumverum (TASMANNIA LANCEOLATA) leaf extract 0.5-3%
Hydroxy phenylpropionyl amine benzoic acid 0.1-0.2%
Bacillus acidi lactici/soya-bean milk tunning filtrate 0.1-2.0%
Tetrahydro methylpyrimidine carboxylic acid 0.1-1.0%.
2. according to antiallergic facial treatment mask described in right 1, which is characterized in that also contain the component of following weight percentage:
Abelmoschus esculentus (HIBISCUS ESCULENTUS) berry extract 0.1-1%
Oat (AVENA SATIVA) beta glucan 0.2-2.0%
The preceding temple seaweed of water (APHANOTHECE SACRUM) polysaccharide 0.1-0.5%
Biological -4 0.1-1% of carbohydrate gum
Cer NP 0.1-0.5%.
3. antiallergic facial treatment mask according to claim 1 or 2, which is characterized in that also containing following weight percentage
Component:
Polyalcohol 4.5-13%
Preservative 0.6-0.75%
Rheology modifiers 0.15-0.45%
PH adjusting agent 0.03-0.12%.
4. antiallergic facial treatment mask according to claim 3, which is characterized in that the polyalcohol is by glycerol, 1,3- the third two
Alcohol, glycerin polyether -26, propylene glycol composition, the glycerol, 1,3-PD, glycerin polyether -26, propylene glycol mass ratio
For (0.5-3): (3-7): (1-3): (0.004-0.02).
5. antiallergic facial treatment mask according to claim 3, which is characterized in that the preservative be parahydroxyacet-ophenone and
The mixing of E59, the parahydroxyacet-ophenone, E59 mass ratio be (0.2-0.3): (0.4-0.45).
6. antiallergic facial treatment mask according to claim 3, which is characterized in that the rheology modifiers are Sodium Polyacrylate
Graft starch and the mixing of acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, the Sodium Polyacrylate connect
Branch starch, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer mass ratio are (0.1-0.25): (0.05-
0.2).
7. antiallergic facial treatment mask according to claim 3, which is characterized in that the pH adjusting agent is aminomethyl third
Alcohol.
8. antiallergic facial treatment mask according to claim 1 or 2, which is characterized in that also containing following weight percentage
Component:
Blue camomile essential oil 0.001-0.005%.
9. antiallergic facial treatment mask according to claim 1 or 2, which is characterized in that also containing following weight percentage
Component:
EDTA disodium 0.02-0.05%
Polyglutamic acid 0.02-0.05%
Allantoin 0.05-0.2%
Hydrolecithin 0.2-0.5%
Bai Chihua (LIMNANTHES ALBA) seed oil 0.1-0.3%
Isononyl isononanoate 0.1-0.5%
PPG-10 methyl ether 0.4-1%
- 9 0.005-0.025% of C12-13 Pareth.
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| CN114681385A (en) * | 2022-03-15 | 2022-07-01 | 北京至乐界生物科技有限公司 | Soothing and repairing composition, preparation method and application in sensitive muscle repair |
| CN115944576A (en) * | 2022-11-21 | 2023-04-11 | 烟台新时代健康产业日化有限公司 | Composition for repairing sensitive skin, mask liquid and mask |
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Application publication date: 20190315 |