CN113712874A - Skin care product containing water-soluble silicon element and preparation method and application thereof - Google Patents

Abstract

The invention discloses a skin care product containing water-soluble silicon element and a preparation method and application thereof, belonging to the technical field of daily skin care products. The skin care product with the functions of whitening, moisturizing and resisting aging is prepared by reasonably mixing the kappaphycus alvarezii extract, the undaria pinnatifida extract, the codonopsis pilosula extract and the grape seed extract with water-soluble silicon, lecithin, nicotinamide and lysine and then assisting with common matrix components of cosmetics, including an emulsifier, an emollient, a humectant, a thickener, a pH regulator, an antioxidant and ionized water. The composition is prepared from natural plants, has high absorption and utilization rate and human body affinity, and can achieve the purpose of supplementing silicon and ensure the health of human bodies by matching with other components required by human bodies. The composition has the advantages of exerting a synergistic effect, having good inhibitory activity on tyrosinase, effectively eliminating melanin on skin, whitening skin, keeping the skin white, having strong moisturizing effect and long duration, effectively enhancing skin elasticity and having an anti-aging effect.

Description

Skin care product containing water-soluble silicon element and preparation method and application thereof

Technical Field

The invention belongs to the technical field of daily skin care products, and particularly relates to a skin care product containing water-soluble silicon element and having whitening, moisturizing and anti-aging effects, and a preparation method and application thereof.

Background

Skin aging is the result of the combined action of the intrinsic physiological mechanism of human aging and the damage caused by external wind, sunshine, environmental pollution and the like. Reasonable nutrition can partially inhibit physiological aging, but is difficult to protect the skin from the external environment. Premature aging of the skin can only be inhibited by timely supplementation of nutrients. Skin aging is usually manifested in skin elasticity, skin wrinkles and roughness, and moisturizing intensity.

The simple use of moisturizers in daily life is obviously insufficient for preventing skin aging. Environmental, sunlight, pressure and other factors can cause free radicals to greatly damage skin and promote skin aging to accelerate. At this time, the skin is also prone to spots, fine lines and the like, so that an antioxidant skin care product is required. Aging causes body aging, slow skin metabolism, and degeneration of collagen and elastic fiber of skin. It is generally believed that the use of skin care products that compact the skin is desirable to slow the aging of the skin. The anti-aging skin care products and raw materials on the market are more, but the existing anti-wrinkle skin care products on the market are easy to stimulate the skin, can cause irreversible damage to the skin and have limited action effect.

Disclosure of Invention

The invention aims to overcome the defects in the prior art and provides a skin care product containing water-soluble silicon element, a preparation method and application thereof, wherein the skin care product has reasonable compatibility and synergistic interaction.

In order to realize the purpose of the invention, the technical scheme adopted by the invention is as follows:

the first aspect of the technical scheme of the invention provides a skin care product containing water-soluble silicon, which comprises the following raw materials in parts by weight: 1-3 parts of Kappaphycus alvarezii extract, 3-5 parts of water-soluble silicon, 0.5-1.5 parts of lecithin, 3-5 parts of Undaria pinnatifida extract, 1-2 parts of nicotinamide, 3-5 parts of lysine, 5-8 parts of radix codonopsis extract, 8-12 parts of grape seed extract, 2-7 parts of emulsifier, 7-12 parts of emollient, 5-10 parts of humectant, 1-3 parts of thickener, 0.1-2 parts of pH regulator, 0.2-0.5 part of antioxidant and 100-120 parts of ionized water.

Further, the feed comprises the following raw materials in parts by weight: 2 parts of Kappaphycus alvarezii extract, 4 parts of water-soluble silicon element, 1 part of lecithin, 4 parts of Undaria pinnatifida extract, 1.5 parts of nicotinamide, 4 parts of lysine, 6 parts of codonopsis pilosula extract, 10 parts of grape seed extract, 5 parts of emulsifier, 10 parts of emollient, 8 parts of humectant, 2 parts of thickener, 1 part of pH regulator, 0.3 part of antioxidant and 110 parts of ionized water.

Further, the emulsifier is selected from one or more of PEG-10 polydimethylsiloxane, laureth-7, sorbitan tristearate and polyglycerol-3 methyl glucose distearate, and is mixed in any proportion.

Further, the emollient is selected from one or more of polydimethylsiloxane, dimethiconol, cyclopentadimethylsiloxane and ethylhexyl palmitate, and is mixed in any proportion.

Further, the humectant is selected from one or two of 1, 3-propylene glycol and sodium hyaluronate which are mixed in any proportion.

Further, the thickening agent is selected from any one or more of xanthan gum, pectin, acacia gum, sclerotium rolfsii gum and hydroxymethyl cellulose which are mixed in any proportion.

Further, the pH regulator is selected from one of sodium bicarbonate, phosphate buffer and citric acid buffer.

Further, the antioxidant is selected from any one or more of alpha-arbutin, vitamin C, vitamin E and tocopherol which are mixed in any proportion.

In a second aspect of the technical solution of the present invention, a method for preparing a skin care product is provided, which is characterized by comprising the following steps:

step one, weighing raw materials according to parts by weight;

step two, adding the humectant and the thickener into ionized water, stirring and heating to 70-80 ℃;

mixing the emulsifier and the emollient, stirring and heating to 70-80 ℃;

step four, adding the preparation obtained in the step three into the preparation obtained in the step two, adding the pH regulator and the antioxidant, stirring and cooling to 30-40 ℃;

adding the kappaphycus alvarezii extract, the undaria pinnatifida extract, the codonopsis pilosula extract, the grape seed extract, the water-soluble silicon element, the lecithin, the nicotinamide and the lysine, continuously stirring and cooling to room temperature;

and step six, subpackaging the products.

In the third aspect of the technical scheme, the invention provides the application of the skin care product as a human body external preparation in whitening, moisturizing and anti-aging.

The invention has the beneficial effects that:

the skin care product with the effects of whitening, moisturizing and resisting aging is prepared by reasonably matching and using the kappaphycus alvarezii extract, the undaria pinnatifida extract, the codonopsis pilosula extract and the grape seed extract with water-soluble silicon, lecithin, nicotinamide and lysine, and then assisting with common matrix components of cosmetics, such as an emulsifier, an emollient, a humectant, a thickener, a pH regulator, an antioxidant, ionized water and the like.

The composition is prepared from natural plants, has high absorption and utilization rate and human body affinity, and can achieve the purpose of supplementing silicon and ensure the health of human bodies by matching with other components required by human bodies. The composition has the advantages of exerting a synergistic effect, having good inhibitory activity on tyrosinase, effectively eliminating melanin on skin, whitening skin, keeping the skin white, having strong moisturizing effect and long duration, effectively enhancing skin elasticity and having an anti-aging effect.

The water-soluble silicon element is a water-soluble silicon element, is generally extracted from diatom or rice in the prior art, can quickly permeate into cells due to the fact that the water-soluble silicon element has 0.4 nanometer fine molecules, and can be quickly absorbed and digested due to strong permeability to skin. It has high absorption and utilization rate and affinity for human body, and can supplement silicon by matching with other components required by human body, thereby ensuring human health.

The Kappaphycus alvarezii extract is rich in mineral substances, amino acids, vitamins and carotenoid components, activates silicon element in water-soluble silicon element, interacts with the silicon element, inhibits the generation of Maillarine cells causing skin tarnish, and has the effects of whitening and fading spots; the skin structure can be strengthened to rebuild and repair the damaged skin, heavy metal can be absorbed and discharged, and skin toxin can be removed; various amino acids in Kappaphycus alvarezii extract can activate skin stem cells and promote skin metabolism.

The undaria pinnatifida extract is a natural biological immune system, can be mutually cooperated with silicon elements in water-soluble silicon elements, prevents skin from being damaged due to environmental pollution (such as waste, cigarettes, lead and cadmium heavy metals), has an anti-pollution effect, prevents skin from free radical reaction, has an anti-oxidation effect, whitens the skin, can effectively brighten the skin, eliminates and reduces skin stains, and enhances skin cohesion and skin elasticity.

The radix Codonopsis extract has effects of invigorating primordial qi, tranquilizing mind and improving intelligence, and can be used for treating pale complexion and hair loss due to qi deficiency. The codonopsis pilosula has the effects of expanding skin capillaries, accelerating blood circulation, enhancing cell activity, enhancing nutrition supply of hair follicles and the like, and has a good beautifying effect.

The grape seed extract has antioxidant properties, can help skin to resist oxidation and promote dermal fibroblast proliferation, especially can help skin to resist ultraviolet irradiation of UVB and UVA, protect skin, reduce damage and prevent skin photoaging, and has no irritation to skin.

Detailed Description

The present invention will be described in further detail with reference to examples, but the embodiments of the present invention are not limited thereto.

[ example 1 ]

Composition 1 of the invention:

a skin care product containing water-soluble silicon element and having whitening, moisturizing and anti-aging effects comprises the following raw materials in parts by weight: the composition comprises, by weight, 1 part of kappaphycus alvarezii extract, 3 parts of water-soluble silicon, 0.5 part of lecithin, 3 parts of undaria pinnatifida extract, 1 part of nicotinamide, 3 parts of lysine, 5 parts of codonopsis pilosula extract, 8 parts of grape seed extract, 2 parts of emulsifier, 7 parts of emollient, 5 parts of humectant, 1 part of thickener, 0.1 part of pH regulator, 0.2 part of antioxidant and 100 parts of ionized water.

Wherein the emulsifier is PEG-10 polydimethylsiloxane. The emollient is selected from polydimethylsiloxane. The humectant is selected from 1, 3-propylene glycol. The thickener is xanthan gum. The pH regulator is sodium bicarbonate. The antioxidant is alpha-arbutin.

The preparation method comprises the following steps: (1) weighing the raw materials according to the parts by weight; (2) adding 1, 3-propylene glycol and xanthan gum into ionized water, stirring and heating to 70 ℃; (3) mixing PEG-10 polydimethylsiloxane and polydimethylsiloxane, stirring and heating to 70 ℃; (4) adding the preparation obtained in the step (3) into the preparation obtained in the step (2), adding sodium bicarbonate and alpha-arbutin, stirring and cooling to 30 ℃; (5) adding Kappaphycus alvarezii extract, Undaria pinnatifida extract, radix Codonopsis extract, grape seed extract, water-soluble silicon, lecithin, nicotinamide and lysine, stirring and cooling to room temperature; (6) and (5) subpackaging the product.

[ example 2 ]

Composition 2 of the invention:

a skin care product containing water-soluble silicon element and having whitening, moisturizing and anti-aging effects comprises the following raw materials in parts by weight: 2 parts of Kappaphycus alvarezii extract, 4 parts of water-soluble silicon element, 1 part of lecithin, 4 parts of Undaria pinnatifida extract, 1.5 parts of nicotinamide, 4 parts of lysine, 6 parts of codonopsis pilosula extract, 10 parts of grape seed extract, 5 parts of emulsifier, 10 parts of emollient, 8 parts of humectant, 2 parts of thickener, 1 part of pH regulator, 0.3 part of antioxidant and 110 parts of ionized water.

Wherein the emulsifier is laureth-7. The emollient is selected from dimethiconol. The humectant is sodium hyaluronate. The thickening agent is selected from pectin and acacia gum, and the thickening agent is prepared from the following components in percentage by weight of 1: 1, and mixing. The pH regulator is phosphate buffer solution. The antioxidant is prepared by mixing vitamin C and vitamin E in a ratio of 2: 3, and mixing.

The preparation method comprises the following steps: (1) weighing the raw materials according to the parts by weight; (2) mixing sodium hyaluronate, pectin and acacia gum in a ratio of 1: 1, adding the mixture into ionized water, stirring and heating to 75 ℃; (3) mixing laureth-7 and dimethiconol, stirring and heating to 75 deg.C; (4) adding the preparation of step (3) to the preparation of step (2), adding phosphate buffer, vitamin C and vitamin E to a mixture of 2: 3, stirring and cooling to 35 ℃; (5) adding Kappaphycus alvarezii extract, Undaria pinnatifida extract, radix Codonopsis extract, grape seed extract, water-soluble silicon, lecithin, nicotinamide and lysine, stirring and cooling to room temperature; (6) and (5) subpackaging the product.

[ example 3 ]

Composition 3 of the invention:

a skin care product containing water-soluble silicon element and having whitening, moisturizing and anti-aging effects comprises the following raw materials in parts by weight: 3 parts of Kappaphycus alvarezii extract, 5 parts of water-soluble silicon element, 1.5 parts of lecithin, 5 parts of Undaria pinnatifida extract, 2 parts of nicotinamide, 5 parts of lysine, 8 parts of radix codonopsis extract, 12 parts of grape seed extract, 7 parts of emulsifier, 12 parts of emollient, 10 parts of humectant, 3 parts of thickener, 2 parts of pH regulator, 0.5 part of antioxidant and 120 parts of ionized water.

Wherein the emulsifier is selected from sorbitan tristearate and polyglycerol-3-methyl glucose distearate in a weight ratio of 1: 1, and mixing. The emollient is selected from cyclopentadimethylsiloxane and ethylhexyl palmitate in a ratio of 2: 1, and mixing. The humectant is prepared from 1, 3-propylene glycol and sodium hyaluronate in a proportion of 1: 2, and mixing. The thickening agent is prepared from sclerotium rolfsii gum and hydroxymethyl cellulose in a weight ratio of 1: 3, and mixing. The pH regulator is citric acid buffer solution. The antioxidant is tocopherol.

The preparation method comprises the following steps: (1) weighing the raw materials according to the parts by weight; (2) 1, 3-propanediol and sodium hyaluronate in a ratio of 1: 2, sclerotium rolfsii gum and hydroxymethyl cellulose in a ratio of 1: 3, adding the mixture in proportion into ionized water, stirring and heating to 80 ℃; (3) sorbitan tristearate and polyglyceryl-3 methyl glucose distearate were mixed at a ratio of 1: 1, cyclopentadimethylsiloxane and ethylhexyl palmitate in a ratio of 2: 1, stirring and heating to 80 ℃; (4) adding the preparation obtained in the step (3) into the preparation obtained in the step (2), adding a citric acid buffer solution and tocopherol, stirring and cooling to 40 ℃; (5) adding Kappaphycus alvarezii extract, Undaria pinnatifida extract, radix Codonopsis extract, grape seed extract, water-soluble silicon, lecithin, nicotinamide and lysine, stirring and cooling to room temperature; (6) and (5) subpackaging the product.

The advantageous effects of the present invention are specifically described below by way of test examples.

[ test 1 ]

The whitening effect test of the composition of the invention on skin:

the test principle is as follows:

tyrosinase is a polyphenol oxidase, is a key enzyme and a rate-limiting enzyme in the process of forming skin melanin, the activity of tyrosinase is positively correlated with the melanin synthesis amount, and the activity change can cause pigmentation disorder dermatosis. The tyrosinase inhibitor can prevent melanin formation by inhibiting tyrosinase activity, can be used for preventing and treating diseases such as pigmentation, chloasma and the like, and has wide application prospect in the fields of cosmetics and medicines.

Test materials:

l-tyrosine solution (0.5mg/ml), tyrosinase (100U/ml);

compositions 1, 2, 3 according to the invention were formulated as described in examples 1, 2, 3 above.

The test method comprises the following steps:

mouse melanoma B16 cells were harvested from log phase growth and plated onto 6-well cell culture plates for overnight culture. The test samples with a final volume fraction of 5% were added separately, and the untreated group was used as a cell control group, with 2 duplicate wells per group. After 48h of culture, the cells were washed 1 time with PBS, 100. mu.L of lysate was added to each well, the cells were scraped off and collected, and the supernatant was centrifuged. 50 μ L of cell supernatant was applied to a 96-well plate, and 50 μ L of 1% L-dopa solution was added, followed by incubation at 37 ℃ for 1 hour. The M3 plate reader reads the absorbance at 475 nm. Relative tyrosinase activity ═ (assay well absorbance value-blank absorbance value)/(cell control absorbance value-blank absorbance value) × 100%. The inhibitory activity of the compositions 1, 2 and 3 of the present invention on tyrosinase was determined.

And (3) test results:

the inhibitory activity of the compositions of the present invention on tyrosinase is shown in table 1.

The test results show that the compositions 1, 2 and 3 have good tyrosinase inhibitory activity, which indicates that the compositions can prevent melanin formation and have whitening effect.

[ test 2 ]

The moisturizing effect of the composition of the invention on skin was tested:

the test principle is as follows:

water is a substance with the largest dielectric constant on the skin, and when the moisture content of the skin changes, the capacitance value of the skin also changes, so that the moisture content on the surface of the skin can be analyzed by measuring the capacitance value of the skin. The change of the moisture content of the stratum corneum is measured by measuring the change of the capacitance of the stratum corneum of the skin before and after the product is used, so that the moisture content of the stratum corneum of the skin is quantified by the method for evaluating the moisture-preserving effect of the cosmetics, and the change of the moisture content of the skin can be sensitively reflected.

The test method comprises the following steps:

selecting 30 women of 20-35 years old, healthy, normal-skin and non-cosmetic allergy history. A square test area of 3 x 3 square centimeters was drawn on the flexed side of the left and right forearms of the subject, the left arm was used as the test area of the product of the present invention, the composition 2 of the present invention prepared in the foregoing example 2 was used in a small amount and applied uniformly, the corresponding symmetric area of the right arm was used as a blank control, and the moisture content of each test part was measured by a Corneometer CM825 tester three times per side after 0, 1, 2, 3, 4 hours of use of the product, and an average value was obtained.

And (3) test results:

the effect of the compositions of the present invention on skin moisture content is shown in table 2.

Group of	0 hour	1 hour	2 hours	3 hours	4 hours
						Group of the invention	26.36	46.90	44.54	42.02	40.61
Blank control group	26.88	26.10	25.38	25.74	25.37

From the above test results, it can be seen that the skin moisture content was significantly increased after 1 hour in the test population using the composition of the present invention, and was still significantly higher than the control group after 4 hours. The composition has the advantages of moisturizing effect, obvious moisturizing effect and long moisturizing effect.

[ test 3 ]

The anti-aging effect test of the composition of the invention on skin comprises the following steps:

the test principle is as follows:

skin elasticity is reduced due to aging of the skin, so that the skin elasticity is one of important signs for judging the aging of the skin and is an essential item for detecting the efficacy of the anti-aging cosmetic.

The test method comprises the following steps:

selecting 30 women of 20-35 years old, healthy, normal-skin and non-cosmetic allergy history. A square test area of 3X 3 square centimeters was drawn on the flexed side of the left and right forearms of the subject, the left arm was used as the test area of the product of the present invention, and the composition 2 of the present invention prepared in example 2 above was applied in small amounts and evenly spread, and the corresponding symmetric area of the right arm was used as a blank control. And (3) taking 1 week as a treatment course, continuously measuring the skin elasticity curve by using a skin elasticity tester for 4 treatment courses, and evaluating the moisturizing and anti-aging functions of the cosmetics according to the stretching amount and resilience data of the skin.

The experimental results are as follows:

the skin elasticity test is based on the principle of suction and stretching, negative pressure is generated on the surface of the skin to be tested, the skin is sucked into a special test probe, the skin suction depth is measured through a non-contact optical detection system, the measurement result is generally expressed by an index, the unit is 1, and the larger the value is, the stronger the skin elasticity is. The effect of the compositions of the present invention on skin elasticity is shown in table 3.

TABLE 3 skin elasticity test values

Group of	0 week	1 week	2 weeks	3 weeks	4 weeks
						Group of the invention	0.581	0.645	0.693	0.728	0.736
Blank control group	0.583	0.529	0.537	0.510	0.587

From the above test results, it was found that the skin elasticity value of the test subjects using the composition of the present invention gradually increased within 4 weeks, and the skin elasticity value was remarkably increased after 4 weeks. Compared with a control group, the composition of the invention can obviously enhance the skin elasticity, which shows that the composition of the invention has the effects of enhancing the skin elasticity and resisting aging.

The embodiments of the present invention are disclosed as the preferred embodiments, but not limited thereto, and those skilled in the art can easily understand the spirit of the present invention and make various extensions and changes without departing from the spirit of the present invention.

Claims (10)

1. A skin care product containing water-soluble silicon is characterized by comprising the following raw materials in parts by weight: 1-3 parts of Kappaphycus alvarezii extract, 3-5 parts of water-soluble silicon, 0.5-1.5 parts of lecithin, 3-5 parts of Undaria pinnatifida extract, 1-2 parts of nicotinamide, 3-5 parts of lysine, 5-8 parts of radix codonopsis extract, 8-12 parts of grape seed extract, 2-7 parts of emulsifier, 7-12 parts of emollient, 5-10 parts of humectant, 1-3 parts of thickener, 0.1-2 parts of pH regulator, 0.2-0.5 part of antioxidant and 100-120 parts of ionized water.

2. The skin care product according to claim 1, characterized by comprising the following raw materials in parts by weight: 2 parts of Kappaphycus alvarezii extract, 4 parts of water-soluble silicon element, 1 part of lecithin, 4 parts of Undaria pinnatifida extract, 1.5 parts of nicotinamide, 4 parts of lysine, 6 parts of codonopsis pilosula extract, 10 parts of grape seed extract, 5 parts of emulsifier, 10 parts of emollient, 8 parts of humectant, 2 parts of thickener, 1 part of pH regulator, 0.3 part of antioxidant and 110 parts of ionized water.

3. The skin care product according to claim 1 or 2, wherein the emulsifier is one or more selected from the group consisting of PEG-10 polydimethylsiloxane, laureth-7, sorbitan tristearate, and polyglyceryl-3 methyl glucose distearate, which are mixed in any proportion.

4. The skin care product according to claim 1 or 2, wherein the emollient is one or more selected from polydimethylsiloxane, dimethiconol, cyclopentadimethylsiloxane and ethylhexyl palmitate, and is mixed in any proportion.

5. The skin care product according to claim 1 or 2, wherein the humectant is one or two selected from 1, 3-propylene glycol and sodium hyaluronate, and the humectant is mixed in any proportion.

6. The skin care product according to claim 1 or 2, wherein the thickener is one or more selected from xanthan gum, pectin, acacia gum, sclerotium rolfsii gum and hydroxymethyl cellulose, and is mixed in any proportion.

7. The skin care product according to claim 1 or 2, wherein the pH adjusting agent is selected from one of sodium bicarbonate, phosphate buffer, and citric acid buffer.

8. The skin care product according to claim 1 or 2, wherein the antioxidant is selected from any one or more of alpha-arbutin, vitamin C, vitamin E and tocopherol, and is mixed in any proportion.

9. A method of preparing a skin care product according to any one of claims 1 to 8, comprising the steps of:

step one, weighing raw materials according to parts by weight;

step two, adding the humectant and the thickener into ionized water, stirring and heating to 70-80 ℃;

mixing the emulsifier and the emollient, stirring and heating to 70-80 ℃;

step four, adding the preparation obtained in the step three into the preparation obtained in the step two, adding the pH regulator and the antioxidant, stirring and cooling to 30-40 ℃;

adding the kappaphycus alvarezii extract, the undaria pinnatifida extract, the codonopsis pilosula extract, the grape seed extract, the water-soluble silicon element, the lecithin, the nicotinamide and the lysine, continuously stirring and cooling to room temperature;

and step six, subpackaging the products.

10. Use of the skin care product of any one of claims 1 to 8 as a preparation for external use on human body for whitening, moisturizing and anti-aging.