CN113768807A - Multi-effect anti-hair loss shampoo and preparation method thereof - Google Patents

Abstract

The invention provides a multi-effect anti-hair loss shampoo and a preparation method thereof, relating to the technical field of daily chemical products, wherein the shampoo comprises the following raw materials: the hair loss preventing shampoo comprises an anti-hair loss extracting solution, a synergist, a foaming agent, a thickening agent, a conditioning agent, an acidity regulator, an antipruritic agent, a viscosity regulator, a humectant, a preservative, a dandruff removing agent, essence and water. The multi-effect anti-hair loss shampoo is simple in preparation method, and the prepared product can fully exert the anti-hair loss efficacy of the plant extract, regulate the micro environment of the scalp, promote the hair follicles to be fully absorbed, and meanwhile has no stimulation and stronger safety.

Description

Multi-effect anti-hair loss shampoo and preparation method thereof

Technical Field

The invention relates to the technical field of daily chemical products, and in particular relates to a multi-effect anti-hair loss shampoo and a preparation method thereof.

Background

Alopecia refers to the phenomenon of hair loss, wherein normal hair loss is the hair in catagen and telogen stages, while pathological alopecia is the phenomenon of abnormal or excessive hair loss, and at present, the causes of pathological alopecia generally include androgenetic alopecia, nutritional alopecia, physical alopecia, endocrine alopecia, infectious alopecia, and the like. In the prior art, chemical synthetics such as finasteride, minoxidil and the like are generally adopted to prevent and treat pathological alopecia, but the chemical synthetics are harmful to human bodies after being used for a long time, so that most consumers can select the shampoo with the hair loss prevention function aiming at the hair loss problem, and the hair loss problem is prevented or treated more safely and effectively.

The prior art discloses a preparation case of partial anti-hair loss shampoo at present, for example, Chinese patent 201910098334.X discloses a multi-effect anti-hair loss shampoo and a preparation method thereof, wherein the shampoo comprises the following components and raw materials in percentage by mass: 5 to 20 percent of multi-effect anti-hair loss extracting solution, 10 to 30 percent of foaming agent, 0.5 to 5 percent of thickening agent, 1 to 5 percent of conditioning agent, 0.1 to 1 percent of acidity regulator, 0.1 to 1 percent of antipruritic agent, 1 to 4 percent of viscosity regulator, 0.05 to 1 percent of humectant, 0.1 to 2 percent of preservative, 0.1 to 2 percent of essence and 40 to 70 percent of water. The shampoo provided by the invention can fully exert the special effects of the Chinese herbal medicines, can be quickly absorbed by hair follicles, does not stimulate hairs, does not damage hairs, can be quickly absorbed into the deep parts of the hair follicles, promotes the blood circulation of scalp, keeps the life vitality of the hair follicles, has the advantages of hair growth and continuously improving alopecia, and is suitable for all types of alopecia crowds. However, a certain amount of preservative is required to be added in the preparation of the shampoo and the preparation of the multi-effect anti-hair loss extracting solution, and although the shelf life of the product is prolonged to a certain extent by adding the preservative, the steady state of the microenvironment of the scalp is influenced to a certain extent. Chinese patent 201811058819.8 discloses an anti-hair loss shampoo and its preparation method, which comprises plant extracts 15% by weight; the plant extract comprises radix Sophorae Flavescentis extract, folium Platycladi extract, cortex Cinchonae extract and eclipta prostrata extract. Further comprising: 20% of foaming agent, 1.5% of thickening agent, 2.85% of conditioning agent, 0.2% of acidity regulator, 0.12% of antipruritic agent, 0.3% of scurf remover, 0.4% of viscosity regulator, 0.1% of humectant, 0.4% of essence, 0.5% of preservative and the balance of water. The shampoo has effects of rapidly penetrating, promoting scalp blood circulation, promoting scalp nutrition supply, activating hair follicle, and preventing hair loss. Has no side effect and no harm to human health. However, the shampoo of the present invention has an insufficient anti-alopecia efficacy as a whole.

Aiming at the problems of weak efficacy, high preservative addition and the like of the existing shampoo with the anti-hair loss effect, the novel trend of the current research is to find a shampoo with low preservative addition and high safety so as to fully exert the efficacy of raw materials under the condition of adding similar efficacy raw materials on the premise of ensuring the micro-environment of the scalp and effectively prevent and treat the hair loss.

Disclosure of Invention

The invention provides a multi-effect anti-hair loss shampoo and a preparation method thereof, aiming at the problems in the prior art, the preparation method of the multi-effect anti-hair loss shampoo is simple, and the prepared product can fully exert the anti-hair loss efficacy of a plant extract, regulate the micro environment of scalp, promote the hair follicle to be fully absorbed, and has no stimulation and stronger safety.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

the invention provides a shampoo which comprises the following raw materials: the hair loss preventing shampoo comprises an anti-hair loss extracting solution, a synergist, a foaming agent, a thickening agent, a conditioning agent, an acidity regulator, an antipruritic agent, a viscosity regulator, a humectant, a preservative, a dandruff removing agent, essence and water.

Further, the shampoo comprises the following raw materials in parts by weight: 8-22 parts of anti-hair loss extracting solution, 2-4 parts of synergist, 8-25 parts of foaming agent, 3-6 parts of thickening agent, 0.5-6 parts of conditioner, 0.3-1.2 parts of acidity regulator, 0.3-1.2 parts of antipruritic agent, 0.8-2.5 parts of viscosity regulator, 0.05-1 part of humectant, 0.1-0.5 part of preservative, 0.2-0.6 part of scurf remover, 0.1-2 parts of essence and 35-75 parts of water.

Preferably, the shampoo comprises the following raw materials in parts by weight: 12-18 parts of anti-hair loss extracting solution, 3-4 parts of synergist, 12-20 parts of foaming agent, 4-5 parts of thickening agent, 2-5 parts of conditioner, 0.8-1 part of acidity regulator, 0.5-1 part of antipruritic agent, 1-1.5 parts of viscosity regulator, 0.08-1 part of humectant, 0.15-0.4 part of preservative, 0.3-0.5 part of scurf remover, 0.15-2 parts of essence and 45-60 parts of water.

Further preferably, the shampoo comprises the following raw materials in parts by weight: 15 parts of anti-hair loss extracting solution, 3.5 parts of synergist, 15 parts of foaming agent, 4.5 parts of thickener, 3 parts of conditioner, 1 part of acidity regulator, 0.6 part of antipruritic agent, 1.2 parts of viscosity regulator, 1 part of humectant, 0.2 part of preservative, 0.4 part of scurf remover, 0.5 part of essence and 50 parts of water.

Further, the synergist is tetrahydropiperine, oat beta-glucan and isopropyl myristate. Preferably 4-5:1-2:1-2 by weight of tetrahydropiperine, oat beta glucan and isopropyl myristate.

Further, the anti-hair loss extracting solution comprises plant extracts, theanine and EDTA-disodium.

Preferably, the weight ratio of the plant extract, the theanine and the EDTA-disodium is 10-20:2-5: 0.5-1. Further preferably 15:3: 0.7.

Further, the plant extract comprises one or more of a eclipta prostrata extract, a biota orientalis extract and a cortex allii gigantei extract.

The preparation method of the anti-alopecia extract comprises the following steps: adding 80 parts by weight of 85% ethanol into 3 parts by weight of eclipta prostrata, 4 parts by weight of cacumen biotae and 1 part by weight of cortex allii utilis, carrying out reflux extraction, filtering the reflux extracting solution, adding activated carbon into the filtered extracting solution for decolorization, filtering again, concentrating the filtered extracting solution, and preparing the concentrated extracting solution into an extract; and mixing the extract with propylene glycol according to the mass ratio of 1:2 to obtain the plant extract. Mixing the formula amount of plant extract with theanine of tea and EDTA-disodium to obtain the anti-hair loss extract.

Further, the foaming agent is sodium laureth sulfate and sodium trideceth sulfate.

Further, the conditioning agent comprises a skin conditioning agent, a hair conditioning agent A and a hair conditioning agent B, wherein the skin conditioning agent is di (PPG-2 myristyl polyether-10) adipate; the hair conditioner A is guar gum hydroxypropyl trimethyl ammonium chloride and polyquaternium-10; hair conditioner B is polyquaternium-52 and/or coco dimethyl ammonium hydroxypropyl hydrolyzed keratin. Preferably, the conditioning agents are skin conditioning agent, hair conditioning agent a and hair conditioning agent B in a weight ratio of 2-3:5-7: 1-2.

Further, the thickener is PEG-120 methyl glucose dioleate; the acidity regulator is citric acid; the antipruritic agent is menthol; the anti-dandruff agent is piroctone olamine salt; the viscosity regulator is sodium xylene sulfonate and salt in a weight ratio of 1: 5; the humectant is a saccharide isomer; the preservative is phenoxyethanol.

The invention also provides a preparation method of the shampoo, which comprises the following steps:

(1) adding foaming agent and skin conditioner into water, mixing, heating, adding thickener, stirring at constant temperature, adding hair conditioner A pre-dispersed with water, homogenizing, adding acidity regulator, stirring at constant temperature, and cooling to obtain solution A;

(2) adding an antipruritic agent into the solution A, continuously cooling, and stirring until the antipruritic agent is completely dissolved to obtain a solution B;

(3) and (3) continuously cooling the solution B, sequentially adding the anti-hair loss extracting solution, the synergist, the dandruff removing agent, the hair conditioner B, the viscosity regulator, the humectant, the essence and the preservative, and stirring to obtain the hair conditioner.

Further, the heating temperature in the step (1) is 85 ℃, the thickening agent is added, the constant-temperature stirring time is 10min, the homogenization time is 3min, the acidity regulator is added, the constant-temperature stirring is carried out for 30min, and the temperature is reduced to 60 ℃.

Further, the temperature of the temperature reduction in the step (3) is below 40 ℃.

Further, the technical effects achieved by the invention are as follows:

in addition, the addition amount of the preservative component of the shampoo is less, the damage influence of the shampoo on the scalp microenvironment can be effectively reduced on the premise of no great change in quality guarantee duration, the scalp microenvironment can be favorably regulated, the hair follicle is promoted to be fully absorbed, and the shampoo is free of stimulation and has stronger safety.

Detailed Description

It should be noted that the raw materials used in the present invention are all common commercial products, and thus the sources thereof are not particularly limited.

Example 1

A shampoo comprises the following components in parts by weight: 8 parts of anti-hair loss extracting solution, 2 parts of synergist, 8 parts of foaming agent, 3 parts of thickener, 0.5 part of conditioner, 0.3 part of acidity regulator, 0.3 part of antipruritic agent, 0.8 part of viscosity regulator, 0.05 part of humectant, 0.1 part of preservative, 0.2 part of scurf remover, 0.1 part of essence and 35 parts of water.

Wherein the synergist comprises 4:1:1 weight ratio of tetrahydropiperine, oat beta-glucan and isopropyl myristate. The anti-hair loss extracting solution comprises plant extracts, theanine and EDTA-disodium in a weight ratio of 10:2: 0.5. The preparation method of the anti-alopecia extract comprises the following steps: adding 80 parts by weight of 85% ethanol into 3 parts by weight of eclipta prostrata, 4 parts by weight of cacumen biotae and 1 part by weight of cortex allii utilis, carrying out reflux extraction, filtering the reflux extracting solution, adding activated carbon into the filtered extracting solution for decolorization, filtering again, concentrating the filtered extracting solution, and preparing the concentrated extracting solution into an extract; and mixing the extract with propylene glycol according to the mass ratio of 1:2 to obtain the plant extract. Mixing the formula amount of plant extract with theanine of tea and EDTA-disodium to obtain the anti-hair loss extract.

In addition, the foaming agent is sodium laureth sulfate and sodium trideceth sulfate. The conditioner comprises a skin conditioner, a hair conditioner A and a hair conditioner B in a weight ratio of 2:5:1, wherein the skin conditioner is di (PPG-2 myristyl polyether-10) adipate; the hair conditioner A is guar gum hydroxypropyl trimethyl ammonium chloride; the hair conditioning agent B is polyquaternium-52. The thickening agent is PEG-120 methyl glucose dioleate; the acidity regulator is citric acid; the antipruritic agent is Mentholum; the antidandruff agent is piroctone olamine salt; the viscosity regulator is sodium xylene sulfonate and salt with the weight ratio of 1: 5; the humectant is saccharide isomer; the antiseptic is phenoxyethanol.

The preparation method of the shampoo comprises the following steps:

(1) adding foaming agent and skin conditioner into water, mixing, heating to 85 deg.C, adding thickener, stirring at constant temperature for 10min, adding hair conditioner A pre-dispersed with water, homogenizing for 3min, adding acidity regulator, stirring at constant temperature for 30min, and cooling to obtain solution A;

(2) adding an antipruritic agent into the solution A, continuously cooling, and stirring until the antipruritic agent is completely dissolved to obtain a solution B;

(3) and continuously cooling the solution B to below 40 ℃, sequentially adding the anti-hair loss extracting solution, the synergist, the scurf remover, the hair conditioner B, the viscosity regulator, the humectant, the essence and the preservative, and stirring to obtain the hair conditioner.

Example 2

A shampoo comprises the following components in parts by weight: 22 parts of anti-hair loss extracting solution, 4 parts of synergist, 25 parts of foaming agent, 6 parts of thickener, 6 parts of conditioner, 1.2 parts of acidity regulator, 1.2 parts of antipruritic agent, 2.5 parts of viscosity regulator, 1 part of humectant, 0.5 part of preservative, 0.6 part of scurf remover, 2 parts of essence and 75 parts of water.

Wherein the synergist comprises tetrahydropiperine, oat beta-glucan and isopropyl myristate in a weight ratio of 5:2: 2. The anti-hair loss extracting solution is a plant extract, theanine and EDTA-disodium in a weight ratio of 20:5: 1. The preparation method of the anti-alopecia extract comprises the following steps: adding 80 parts by weight of 85% ethanol into 3 parts by weight of eclipta prostrata, 4 parts by weight of cacumen biotae and 1 part by weight of cortex allii utilis, carrying out reflux extraction, filtering the reflux extracting solution, adding activated carbon into the filtered extracting solution for decolorization, filtering again, concentrating the filtered extracting solution, and preparing the concentrated extracting solution into an extract; and mixing the extract with propylene glycol according to the mass ratio of 1:2 to obtain the plant extract. Mixing the formula amount of plant extract with theanine of tea and EDTA-disodium to obtain the anti-hair loss extract.

In addition, the foaming agent is sodium laureth sulfate and sodium trideceth sulfate. The conditioner comprises a skin conditioner, a hair conditioner A and a hair conditioner B in a weight ratio of 3:7:2, wherein the skin conditioner is di (PPG-2 myristyl polyether-10) adipate; the hair conditioner A is polyquaternium-10; hair conditioner B was coco dimethyl ammonium hydroxypropyl hydrolyzed keratin. The thickening agent is PEG-120 methyl glucose dioleate; the acidity regulator is citric acid; the antipruritic agent is Mentholum; the antidandruff agent is piroctone olamine salt; the viscosity regulator is sodium xylene sulfonate and salt with the weight ratio of 1: 5; the humectant is saccharide isomer; the antiseptic is phenoxyethanol.

The shampoo was prepared in the same manner as in example 1.

Example 3

A shampoo comprises the following components in parts by weight: 15 parts of anti-hair loss extracting solution, 3.5 parts of synergist, 15 parts of foaming agent, 4.5 parts of thickener, 3 parts of conditioner, 1 part of acidity regulator, 0.6 part of antipruritic agent, 1.2 parts of viscosity regulator, 1 part of humectant, 0.2 part of preservative, 0.4 part of scurf remover, 0.5 part of essence and 50 parts of water.

Wherein the synergist comprises 4:2:1 by weight of tetrahydropiperine, oat beta-glucan and isopropyl myristate. The anti-hair loss extracting solution comprises plant extracts, theanine and EDTA-disodium in a weight ratio of 15:3: 0.7. The preparation method of the anti-alopecia extract comprises the following steps: adding 80 parts by weight of 85% ethanol into 3 parts by weight of eclipta prostrata, 4 parts by weight of cacumen biotae and 1 part by weight of cortex allii utilis, carrying out reflux extraction, filtering the reflux extracting solution, adding activated carbon into the filtered extracting solution for decolorization, filtering again, concentrating the filtered extracting solution, and preparing the concentrated extracting solution into an extract; and mixing the extract with propylene glycol according to the mass ratio of 1:2 to obtain the plant extract. Mixing the formula amount of plant extract with theanine of tea and EDTA-disodium to obtain the anti-hair loss extract.

In addition, the foaming agent is sodium laureth sulfate and sodium trideceth sulfate. The conditioner comprises a skin conditioner, a hair conditioner A and a hair conditioner B in a weight ratio of 2:6:1, wherein the skin conditioner is di (PPG-2 myristyl polyether-10) adipate; the hair conditioner A is guar gum hydroxypropyl trimethyl ammonium chloride; the hair conditioning agent B is polyquaternium-52. The thickening agent is PEG-120 methyl glucose dioleate; the acidity regulator is citric acid; the antipruritic agent is Mentholum; the antidandruff agent is piroctone olamine salt; the viscosity regulator is sodium xylene sulfonate and salt with the weight ratio of 1: 5; the humectant is saccharide isomer; the antiseptic is phenoxyethanol.

The shampoo was prepared in the same manner as in example 1.

Example 4

A shampoo comprises the following components in parts by weight: 12 parts of anti-hair loss extracting solution, 3 parts of synergist, 12 parts of foaming agent, 4 parts of thickener, 2 parts of conditioner, 0.8 part of acidity regulator, 0.5 part of antipruritic agent, 1 part of viscosity regulator, 0.08 part of humectant, 0.15 part of preservative, 0.3 part of scurf remover, 0.15 part of essence and 45 parts of water.

Wherein the synergist comprises tetrahydropiperine, oat beta-glucan and isopropyl myristate in a weight ratio of 5:1: 2. The anti-hair loss extracting solution is a plant extract, theanine and EDTA-disodium in a weight ratio of 20:2: 1. The preparation method of the anti-alopecia extract comprises the following steps: adding 80 parts by weight of 85% ethanol into 3 parts by weight of eclipta prostrata, 4 parts by weight of cacumen biotae and 1 part by weight of cortex allii utilis, carrying out reflux extraction, filtering the reflux extracting solution, adding activated carbon into the filtered extracting solution for decolorization, filtering again, concentrating the filtered extracting solution, and preparing the concentrated extracting solution into an extract; and mixing the extract with propylene glycol according to the mass ratio of 1:2 to obtain the plant extract. Mixing the formula amount of plant extract with theanine of tea and EDTA-disodium to obtain the anti-hair loss extract.

In addition, the foaming agent is sodium laureth sulfate and sodium trideceth sulfate. The conditioner comprises a skin conditioner, a hair conditioner A and a hair conditioner B in a weight ratio of 2:6:1, wherein the skin conditioner is di (PPG-2 myristyl polyether-10) adipate; the hair conditioner A is polyquaternium-10; the hair conditioning agent B is polyquaternium-52. The thickening agent is PEG-120 methyl glucose dioleate; the acidity regulator is citric acid; the antipruritic agent is Mentholum; the antidandruff agent is piroctone olamine salt; the viscosity regulator is sodium xylene sulfonate and salt with the weight ratio of 1: 5; the humectant is saccharide isomer; the antiseptic is phenoxyethanol.

The shampoo was prepared in the same manner as in example 1.

Example 5

A shampoo comprises the following components in parts by weight: 18 parts of anti-hair loss extracting solution, 4 parts of synergist, 20 parts of foaming agent, 5 parts of thickener, 5 parts of conditioner, 1 part of acidity regulator, 1 part of antipruritic agent, 1.5 parts of viscosity regulator, 1 part of humectant, 0.4 part of preservative, 0.5 part of scurf remover, 2 parts of essence and 60 parts of water.

Wherein the synergist comprises tetrahydropiperine, oat beta-glucan and isopropyl myristate in a weight ratio of 5:1: 2. The anti-hair loss extracting solution comprises plant extracts, theanine and EDTA-disodium in a weight ratio of 10:5: 0.5. The preparation method of the anti-alopecia extract comprises the following steps: adding 80 parts by weight of 85% ethanol into 3 parts by weight of eclipta prostrata, 4 parts by weight of cacumen biotae and 1 part by weight of cortex allii utilis, carrying out reflux extraction, filtering the reflux extracting solution, adding activated carbon into the filtered extracting solution for decolorization, filtering again, concentrating the filtered extracting solution, and preparing the concentrated extracting solution into an extract; and mixing the extract with propylene glycol according to the mass ratio of 1:2 to obtain the plant extract. Mixing the formula amount of plant extract with theanine of tea and EDTA-disodium to obtain the anti-hair loss extract.

In addition, the foaming agent is sodium laureth sulfate and sodium trideceth sulfate. The conditioner comprises a skin conditioner, a hair conditioner A and a hair conditioner B in a weight ratio of 3:6:2, wherein the skin conditioner is di (PPG-2 myristyl polyether-10) adipate; the hair conditioner A is guar gum hydroxypropyl trimethyl ammonium chloride; hair conditioner B was coco dimethyl ammonium hydroxypropyl hydrolyzed keratin. The thickening agent is PEG-120 methyl glucose dioleate; the acidity regulator is citric acid; the antipruritic agent is Mentholum; the antidandruff agent is piroctone olamine salt; the viscosity regulator is sodium xylene sulfonate and salt with the weight ratio of 1: 5; the humectant is saccharide isomer; the antiseptic is phenoxyethanol.

The shampoo was prepared in the same manner as in example 1.

Comparative example 1

The only difference from example 1 is that the weight ratio of the plant extract, theanine and EDTA-disodium in the anti-hair loss extract was 8:7:0.3 (the total weight of the three was the same as in example 1).

Comparative example 2

The only difference from example 1 is that no synergist was added.

Comparative example 3

The hair loss prevention shampoo described in example 4 of patent No. cn201910098334.x.

Comparative example 4

The hair loss preventing shampoo described in patent CN201811058819.8 in example 2.

Test 1: the invention discloses a method for researching and testing the effect of shampoo on the growth of mouse hair, which comprises the following steps: 100C 57BL/6 female mice (weight 18-22g) were bred normally for one week, and after normal breeding, depilation was performed in an area of 2cm × 2cm on the back of the mice (rosin and paraffin were mixed at a weight ratio of 1:1, heated and melted and then applied to a designated area on the back of the mice), and then the mice were randomly divided into 10 groups of 10 groups, wherein 1 group was applied with physiological saline only as a blank control group, the remaining groups were applied with 20mg/kg of shampoo in each example, once in the morning and evening, and after 3 weeks, the hair length and the hair weight of the mice in the test area were measured, and the results were counted in Table 1.

TABLE 1

(Note: in the table: p < 0.05 compared to blank, p < 0.01 compared to blank).

Test 2: research on restoration of hair damage of mice by shampoo in the invention

The test method comprises the following steps: 100C 57BL/6 female mice (weight 18-22g) were fed normally for one week, and then were depilated in the area of 2cm × 2cm on the back of the mice, the procedure of the depilating test was the same as test 1, the mice were randomly divided into 10 groups of 10 groups, wherein 1 group was used as a blank control group and only saline was applied thereto, the remaining groups were each applied 20mg/kg of the shampoo of each example and once in the morning and evening, and after one week, 150mg/kg of cyclophosphamide was injected to the mice in a single dose, and after 3 consecutive weeks from the first application of shampoo or saline, the hair length and the hair weight of the mice in the depilated area were measured, and the results were counted in Table 2.

TABLE 2

Examples of the invention	Wool length (mm)	Gross weight (mg/cm)2)
			Blank group	6.16±0.82	18.6±2.1
Example 1	8.84±0.63**	22.4±1.5**
			Example 2	8.79±0.70**	22.6±1.8**
Example 3	9.53±0.78**	23.9±2.6**
			Example 4	8.98±0.81**	23.2±2.4**
Example 5	9.26±0.79**	22.9±2.4**
			Comparative example 1	7.28±0.92*	20.4±1.1*
Comparative example 2	6.89±0.84	19.1±2.8
			Comparative example 3	7.15±0.74*	21.5±1.8**
Comparative example 4	7.06±0.76*	20.9±2.6*

(Note: in the table: p < 0.05 compared to blank, p < 0.01 compared to blank).

As can be seen from tables 1-2 of the present invention, the shampoo of the present invention has excellent effects on the normal hair growth and the restoration of the damaged hair of the mice, and in comparison, when the components in the anti-hair loss extract are changed or no synergist is added, the promoting effect on the hair growth is weakened, and even the product effect is inferior to that of the initial research, mainly because the lack or reduction of the key components affects the compounding effect among other components.

In addition, the shampoo in each embodiment is subjected to safety test according to an acute skin irritation test method in cosmetic hygiene code (2015 edition), and the test result shows that the surface of a mouse of a tested animal has no erythema and no swelling after 24 hours, so that the anti-alopecia shampoo disclosed by the invention has no stimulation to the skin and has high safety.

Finally, it should be noted that the above-mentioned contents are only used for illustrating the technical solutions of the present invention, and not for limiting the protection scope of the present invention, and that the simple modifications or equivalent substitutions of the technical solutions of the present invention by those of ordinary skill in the art can be made without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. A shampoo is characterized in that: the method comprises the following raw materials: the hair loss preventing shampoo comprises an anti-hair loss extracting solution, a synergist, a foaming agent, a thickening agent, a conditioning agent, an acidity regulator, an antipruritic agent, a viscosity regulator, a humectant, a preservative, a dandruff removing agent, essence and water.

2. The shampoo according to claim 1, characterized in that: comprises the following components in parts by weight: 8-22 parts of anti-hair loss extracting solution, 2-4 parts of synergist, 8-25 parts of foaming agent, 3-6 parts of thickening agent, 0.5-6 parts of conditioner, 0.3-1.2 parts of acidity regulator, 0.3-1.2 parts of antipruritic agent, 0.8-2.5 parts of viscosity regulator, 0.05-1 part of humectant, 0.1-0.5 part of preservative, 0.2-0.6 part of scurf remover, 0.1-2 parts of essence and 35-75 parts of water.

3. The shampoo according to claim 2, characterized in that: comprises the following components in parts by weight: 12-18 parts of anti-hair loss extracting solution, 3-4 parts of synergist, 12-20 parts of foaming agent, 4-5 parts of thickening agent, 2-5 parts of conditioner, 0.8-1 part of acidity regulator, 0.5-1 part of antipruritic agent, 1-1.5 parts of viscosity regulator, 0.08-1 part of humectant, 0.15-0.4 part of preservative, 0.3-0.5 part of scurf remover, 0.15-2 parts of essence and 45-60 parts of water.

4. The shampoo according to claim 1, characterized in that: the synergist is tetrahydropiperine, oat beta-glucan and isopropyl myristate.

5. The shampoo according to claim 1, characterized in that: the anti-hair loss extracting solution comprises plant extracts, theanine and EDTA-disodium.

6. The shampoo according to claim 5, characterized in that: the weight ratio of the plant extract, the theanine of the tea leaves and the EDTA-disodium is 10-20:2-5: 0.5-1.

7. The shampoo according to claim 5, characterized in that: the plant extract comprises one or more of eclipta prostrata extract, cacumen biotae extract and cortex allii gigantei extract.

8. The shampoo according to claim 1, characterized in that: the foaming agent is sodium laureth sulfate and sodium trideceth sulfate.

9. The shampoo according to claim 1, characterized in that: the conditioning agent comprises a skin conditioning agent, a hair conditioning agent A and a hair conditioning agent B, wherein the skin conditioning agent is di (PPG-2 myristyl alcohol polyether-10) adipate; the hair conditioner A is guar gum hydroxypropyl trimethyl ammonium chloride and/or polyquaternium-10; hair conditioner B is polyquaternium-52 and/or coco dimethyl ammonium hydroxypropyl hydrolyzed keratin.

10. The method for preparing a shampoo according to claim 9, wherein the shampoo comprises: the method comprises the following steps:

(1) adding foaming agent and skin conditioner into water, mixing, heating, adding thickener, stirring at constant temperature, adding hair conditioner A pre-dispersed with water, homogenizing, adding acidity regulator, stirring at constant temperature, and cooling to obtain solution A;

(2) adding an antipruritic agent into the solution A, continuously cooling, and stirring until the antipruritic agent is completely dissolved to obtain a solution B;

(3) and (3) continuously cooling the solution B, sequentially adding the anti-hair loss extracting solution, the synergist, the dandruff removing agent, the hair conditioner B, the viscosity regulator, the humectant, the essence and the preservative, and stirring to obtain the hair conditioner.