CN113559016A - Amino acid shampoo capable of relieving and relieving itching for dry scalp - Google Patents

Amino acid shampoo capable of relieving and relieving itching for dry scalp Download PDF

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CN113559016A
CN113559016A CN202110820177.6A CN202110820177A CN113559016A CN 113559016 A CN113559016 A CN 113559016A CN 202110820177 A CN202110820177 A CN 202110820177A CN 113559016 A CN113559016 A CN 113559016A
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scalp
amino acid
relieving
shampoo
itching
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林柳城
谢振胜
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Guangzhou Jinan Cosmetics Co ltd
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Guangzhou Jinan Cosmetics Co ltd
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    • AHUMAN NECESSITIES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/34Alcohols
    • A61K8/347Phenols
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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    • AHUMAN NECESSITIES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
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    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds

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Abstract

The invention discloses a soothing and itching-relieving amino acid shampoo for dry scalp and a preparation process thereof. The shampoo contains PPG-28-butanol polyether-35, dipropylene glycol, butanediol, panthenol and 1, 2-pentanediol, which are used for realizing strong effect and lasting moisture retention of scalp; inulin is a prebiotic to realize scalp microecological balance; taurine and aspartic acid impart nutrition to the scalp and hair under the absorption promoting action of PPG-28-Butanethol-35. A mild amino acid surfactant is adopted to obtain a surfactant with large irritation; the antiseptic aims are achieved by adopting mild antiseptic components such as 1, 2-pentanediol, polyglycerol-10 laurate and the like, and the antiseptic replaces the preservative with large irritation such as Kathon and the like. The shampoo disclosed by the invention has the effects of strongly moisturizing the scalp, reducing the irritation of a scalp care product and keeping the microecological balance of the scalp, and can relieve itching after washing the scalp.

Description

Amino acid shampoo capable of relieving and relieving itching for dry scalp
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to a soothing and itching-relieving amino acid shampoo for dry scalp and a preparation process thereof.
Background
Good scalp and good hair.
The scalp is also a portion of the skin that is similar in structure to facial skin, but the scalp is thinner and has more sebaceous glands than facial skin. The density of sebaceous glands on the scalp is reported to be about 144-2About 52-79 pieces/cm on forehead2About 42-78 pieces/cm on cheek2That is, the number of sebaceous glands on the scalp is twice as large as that of the forehead, which is most prone to oil, so that the scalp is more cared for.
As with facial skin, which is dry, neutral, oily, sensitive, our scalp is also sub-natural. The dry scalp is thin, dry and sensitive, and after being dried, the scalp is very easy to cause dandruff, and after being blown by wind and sun, the scalp often has symptoms of redness, burning pain, itching of the head, desquamation and the like.
The reason for dandruff on dry scalp is different from that on oily scalp, and dandruff on oily scalp is caused by excessive oil secretion to provide nutrition for malassezia. Whereas dry dandruff is a peeling phenomenon due to dryness. Therefore, scientific care of dry scalp should be to moisturize scalp and reduce irritation of scalp care products and maintain microecological balance of scalp, rather than to remove dandruff directly with an antibacterial and antidandruff agent as in oily scalp.
At present, scalp care products mostly focus on the sterilization and dandruff removal agent to remove dandruff, which is not applicable to dry scalp. It is an object of the present invention to provide a scalp care regimen for dry scalp.
Disclosure of Invention
The invention aims to overcome the defects of the existing scalp care products and provides the soothing and itching-relieving amino acid shampoo for the dry scalp and the preparation process thereof.
To achieve the above object, the present invention adopts the following technical solution
A soothing and itching-relieving amino acid shampoo for dry scalp comprises sodium lauroyl sarcosinate, sodium cocoyl amino acid, ceteth-20, sodium cocoyl methyl taurate, taurine, aspartic acid, dipropylene glycol, cocamidopropyl hydroxysultaine, sodium chloride, C12-16 alkyl glucoside, PEG-120 methyl glucose dioleate, phenoxyethanol, guar gum hydroxypropyl trimonium chloride, essence, citric acid, disodium EDTA, panthenol, PPG-28-butanol polyether-35, butanediol, 1, 2-pentanediol, salicylic acid, o-cymene-5-ol, inulin, polyglycerol-10 laurate and deionized water.
A soothing and itching-relieving amino acid shampoo for dry scalp is prepared from the following components in parts by mass:
Figure BDA0003171633860000021
Figure BDA0003171633860000031
preferably, the amino acid shampoo for relieving and relieving itching for the dry scalp is prepared from the following components in parts by mass:
sodium lauroyl sarcosinate 2.00-15.00%
Sodium cocoyl amino acid 0.01-4.00%
Ceteth-20 0.01-4.00%
Sodium cocoyl methyl taurate 0.01-3.00%
Taurine 0.01-3.00%
Aspartic acid 0.01-3.00%
Dipropylene glycol 0.01-4.00%
Cocoamidopropyl hydroxysultaine 0.50-7.00%
Sodium chloride 0.02-1.50%
C12-16 alkyl glucoside 0.50-14.00%
PEG-120 methyl glucose dioleate 0.10-1.00%
Phenoxyethanol 0.20-0.90%
Guar hydroxypropyl trimethyl ammonium chloride 0.05-0.40%
Essence 0.10-1.40%
Citric acid 0.05-1.00%
EDTA disodium salt 0.05-0.40%
Panthenol 0.10-4.50%
PPG-28-Butaneth-35 0.01-4.00%
Butanediol 0.10-4.00%
1, 2-pentanediol 0.02-0.80%
Salicylic acid 0.01-0.40%
o-cymene-5-ol 0.01-0.40%
Inulin powder 0.001-0.30%
Polyglycerol-10 laurate 0.01-2.00%
Deionized water Balance of
Preferably, the amino acid shampoo for relieving and relieving itching for the dry scalp is prepared from the following components in parts by mass:
Figure BDA0003171633860000032
Figure BDA0003171633860000041
in order to prepare the shampoo, the invention adopts the following preparation process:
adding deionized water, sodium lauroyl sarcosinate, sodium cocoyl amino acid, ceteth-20, sodium cocoyl methyl taurate, taurine, aspartic acid, dipropylene glycol, C12-16 alkyl glucoside, PEG-120 methyl glucose dioleate, guar hydroxypropyl trimethyl ammonium chloride, citric acid, EDTA disodium, panthenol and butanediol into an emulsifying pot, heating, stirring and dissolving until no particles exist, preserving heat for 30 minutes, sterilizing and defoaming;
cooling to 60 ℃, adding the cocamidopropyl hydroxysultaine, sodium chloride and polyglycerol-10 laurate, and fully and uniformly stirring;
thirdly, cooling to 45 ℃, and adding other components in sequence, fully reducing the volume by half and uniformly;
cooling to 35-38 ℃, sampling, inspecting, and discharging after the product is qualified.
Compared with the prior art, the invention has the following advantages and effects:
1. the PPG-28-butanol polyether-35, dipropylene glycol, butanediol, panthenol and 1, 2-pentanediol are used for realizing synergistic interaction to realize strong effect and lasting moisture preservation of the scalp; inulin is a prebiotic to realize scalp microecological balance; taurine and aspartic acid impart nutrition to the scalp and hair under the absorption promoting action of PPG-28-Butanethol-35.
2. A mild amino acid surfactant is adopted to obtain a surfactant with large irritation; the antiseptic aims are achieved by adopting mild antiseptic components such as 1, 2-pentanediol, polyglycerol-10 laurate and the like, and the antiseptic replaces the preservative with large irritation such as Kathon and the like. The mildness target of the shampoo is achieved.
3. The shampoo disclosed by the invention has the effects of strongly moisturizing the scalp, reducing the irritation of a scalp care product, keeping the microecological balance of the scalp and ensuring that the scalp is washed and relieved to relieve itching.
Detailed Description
The present invention will be described in further detail with reference to examples, but the embodiments of the present invention are not limited thereto.
The test methods in the following examples, in which specific experimental conditions are not specified, are generally performed according to conventional experimental conditions or according to the experimental conditions recommended by the manufacturer.
Examples 1-3 soothing and antipruritic amino acid shampoo for dry scalp
The formulations of the soothing and itching-relieving amino acid shampoos for dry scalp use of examples 1-3 are shown in table 1, and the amounts are in parts by mass.
TABLE 1
Figure BDA0003171633860000051
Figure BDA0003171633860000061
The preparation process comprises the following steps:
adding deionized water, sodium lauroyl sarcosinate, sodium cocoyl amino acid, ceteth-20, sodium cocoyl methyl taurate, taurine, aspartic acid, dipropylene glycol, C12-16 alkyl glucoside, PEG-120 methyl glucose dioleate, guar hydroxypropyl trimethyl ammonium chloride, citric acid, EDTA disodium, panthenol and butanediol into an emulsifying pot, heating, stirring and dissolving until no particles exist, preserving heat for 30 minutes, sterilizing and defoaming;
cooling to 60 ℃, adding the cocamidopropyl hydroxysultaine, sodium chloride and polyglycerol-10 laurate, and fully and uniformly stirring;
thirdly, cooling to 45 ℃, and adding other components in sequence, fully reducing the volume by half and uniformly;
cooling to 35-38 ℃, sampling, inspecting, and discharging after the product is qualified.
Experimental example 1 evaluation of moisturizing Effect
1. Sample preparation and instrumentation
Shampoo samples prepared in examples 1-3 were prepared separately and subjected to the following experiments.
The experimental apparatus was a skin moisture Corneometer test probe manufactured by Courage + Khazaka, Germany (CK, Germany).
2. Principle of experiment
The higher the skin moisture, the higher the skin moisture content and the lower the TEWL value for skin moisture loss.
3. Skin moisture content testing method
The water content test in the experiment adopts
Figure BDA0003171633860000072
Farad-capacitive method.
100 dry skin people are selected, wherein the age is 20-45 years, and the age is half of that of men and women. Before the test, the subject was asked to sit still in a constant temperature and humidity room at 22 + -1 deg.C and 50 + -5% humidity for 30min and to maintain a relaxed state.
The skin moisture content test was performed on the parietal median skin of the volunteers, and the average of 3 values was taken as the moisture content data (D0). After the test is finished, the volunteers need to use the shampoo according to the requirements, the shampoo is used for continuous trial for 28 days every day, and the 14 th (D14) and 28 th (D28) days of the trial are required for return visit.
4. Test results
The results of the moisture content change rate test are shown in table 2.
Example 1 22.9±2.9 29.3±2.5
Example 2 23.6±4.1 30.4±2.9
Example 3 22.2±4.2 30.1±3.2
The result shows that the shampoo provided by the invention has a good moisturizing effect.
Experimental example 2 evaluation test for scalp Care efficacy
200 dry scalp volunteer subjects with scurf and head itch problems are screened, wherein 80 male subjects and 120 female subjects are aged 25-50 years old. Volunteer subjects were randomly divided into control groups, example 1 groups, 100 per group. The control group is given a shampoo suitable for dry hair of a certain international brand name, and about 5mL of shampoo is taken each time for 1 time per day; example 1 the group was shampooed with the shampoo prepared in example 1 and applied 1 time daily at a dose of about 5 mL. After one month of continuous use, the improvement of dandruff and itching was evaluated and the results are shown in Table 3.
TABLE 3
Figure BDA0003171633860000071
Figure BDA0003171633860000081
The result shows that the shampoo prepared in the embodiment 1 of the invention has better hair care effect, can obviously reduce dandruff and head itching, has better effect than the shampoo which is suitable for dry hair of a certain international known brand on the market, and can not cause the increase of dandruff and head itching.
The embodiments of the present invention have been described in detail, but the embodiments are merely examples, and the present invention is not limited to the embodiments described above. Any equivalent modifications and substitutions to those skilled in the art are also within the scope of the present invention. Accordingly, equivalent changes and modifications made without departing from the spirit and scope of the present invention should be covered by the present invention.

Claims (5)

1. A soothing and itching-relieving amino acid shampoo for dry scalp is characterized by comprising sodium lauroyl sarcosinate, sodium cocoyl amino acid, cetyl alcohol polyether-20, sodium cocoyl methyl taurate, taurine, aspartic acid, dipropylene glycol, cocamidopropyl hydroxysultaine, sodium chloride, C12-16 alkyl glucoside, PEG-120 methyl glucose dioleate, phenoxyethanol, guar hydroxypropyl trimethyl ammonium chloride, essence, citric acid, EDTA disodium, panthenol, PPG-28-butanol polyether-35, butanediol, 1, 2-pentanediol, salicylic acid, o-cymene-5-ol, inulin, polyglycerol-10 laurate and deionized water.
2. The amino acid shampoo for relieving and relieving itching of the dry scalp is characterized by being prepared from the following components in parts by mass:
Figure FDA0003171633850000011
3. the amino acid shampoo for relieving and relieving itching of the dry scalp is characterized by being prepared from the following components in parts by mass:
Figure FDA0003171633850000021
4. the amino acid shampoo for relieving and relieving itching of the dry scalp is characterized by being prepared from the following components in parts by mass:
Figure FDA0003171633850000022
Figure FDA0003171633850000031
5. the preparation process of the amino acid shampoo for relieving itching for the dry scalp, which is used for the dry scalp, is characterized by comprising the following steps,
adding deionized water, sodium lauroyl sarcosinate, sodium cocoyl amino acid, ceteth-20, sodium cocoyl methyl taurate, taurine, aspartic acid, dipropylene glycol, C12-16 alkyl glucoside, PEG-120 methyl glucose dioleate, guar hydroxypropyl trimethyl ammonium chloride, citric acid, EDTA disodium, panthenol and butanediol into an emulsifying pot, heating, stirring and dissolving until no particles exist, preserving heat for 30 minutes, sterilizing and defoaming;
cooling to 60 ℃, adding the cocamidopropyl hydroxysultaine, sodium chloride and polyglycerol-10 laurate, and fully and uniformly stirring;
thirdly, cooling to 45 ℃, and adding other components in sequence, fully reducing the volume by half and uniformly;
cooling to 35-38 ℃, sampling, inspecting, and discharging after the product is qualified.
CN202110820177.6A 2021-07-20 2021-07-20 Amino acid shampoo capable of relieving and relieving itching for dry scalp Pending CN113559016A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115501124A (en) * 2022-11-10 2022-12-23 广州百孚润化工有限公司 Scalp care composition, preparation method thereof and scalp care agent

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115501124A (en) * 2022-11-10 2022-12-23 广州百孚润化工有限公司 Scalp care composition, preparation method thereof and scalp care agent
CN115501124B (en) * 2022-11-10 2023-09-08 广州百孚润化工有限公司 Scalp care composition, preparation method thereof and scalp care agent

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