CN1133007A - 二氢和四氢苯并[f]喹啉-3-酮 - Google Patents

二氢和四氢苯并[f]喹啉-3-酮 Download PDF

Info

Publication number
CN1133007A
CN1133007A CN94193758A CN94193758A CN1133007A CN 1133007 A CN1133007 A CN 1133007A CN 94193758 A CN94193758 A CN 94193758A CN 94193758 A CN94193758 A CN 94193758A CN 1133007 A CN1133007 A CN 1133007A
Authority
CN
China
Prior art keywords
chemical compound
medicine
alpha
quinoline
ketone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94193758A
Other languages
English (en)
Chinese (zh)
Inventor
D·A·霍尔特
D·S·山下
H·K·严
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1133007A publication Critical patent/CN1133007A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN94193758A 1993-08-20 1994-08-19 二氢和四氢苯并[f]喹啉-3-酮 Pending CN1133007A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9317314.4 1993-08-20
GB939317314A GB9317314D0 (en) 1993-08-20 1993-08-20 Compounds

Publications (1)

Publication Number Publication Date
CN1133007A true CN1133007A (zh) 1996-10-09

Family

ID=10740766

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94193758A Pending CN1133007A (zh) 1993-08-20 1994-08-19 二氢和四氢苯并[f]喹啉-3-酮

Country Status (8)

Country Link
EP (1) EP0724440A4 (fr)
JP (1) JPH09501695A (fr)
CN (1) CN1133007A (fr)
AU (1) AU7634194A (fr)
CA (1) CA2169750A1 (fr)
GB (1) GB9317314D0 (fr)
WO (1) WO1995005821A1 (fr)
ZA (1) ZA946308B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037326A (en) * 1996-12-31 2000-03-14 Styczynski; Peter Reduction of hair growth
GB0129567D0 (en) 2001-12-11 2002-01-30 Trikon Technologies Ltd Diffusion barrier

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5198300A (en) * 1975-02-20 1976-08-30 Kanputoteshin oyobi sonoruijitaino seizoho
CA1110234A (fr) * 1978-01-18 1981-10-06 Hoffmann-La Roche Limited Acides 4-pyridone-3-carboxyliques et procede de fabrication
YU7087A (en) * 1986-01-23 1988-06-30 Hoffmann La Roche Process for obtaining benzazecine derivatives
US5250539A (en) * 1991-08-21 1993-10-05 Eli Lilly And Company Hexahydrobenzo[f]quinolinones
US5239075A (en) * 1991-08-21 1993-08-24 Eli Lilly And Company Process for the preparation of benzo (f) quinolinones

Also Published As

Publication number Publication date
EP0724440A4 (fr) 1996-11-20
ZA946308B (en) 1995-04-03
GB9317314D0 (en) 1993-10-06
CA2169750A1 (fr) 1995-03-02
EP0724440A1 (fr) 1996-08-07
WO1995005821A1 (fr) 1995-03-02
AU7634194A (en) 1995-03-21
JPH09501695A (ja) 1997-02-18

Similar Documents

Publication Publication Date Title
CN1155600C (zh) 2,3-二芳基吡唑并[1,5-b]哒嗪衍生物,其制备方法和用作环氧酶2抑制剂
CN1198594C (zh) 治疗用活性组合物
CN1136219C (zh) 用于治疗阳痿的吡唑并嘧啶酮衍生物
CN1095841C (zh) 化合物
CN1057771C (zh) 雄烯酮衍生物
CN1960991A (zh) 用作醛固酮合酶抑制剂的四氢咪唑并[1,5－a]吡啶衍生物
JP2014511395A (ja) Ｐｉ３キナーゼインヒビターおよびその使用
WO2015136016A2 (fr) Combinaisons thérapeutiques avec des modulateurs du récepteur des œstrogènes
CN1633287A (zh) 联苯衍生物及其作为抗雄激素试剂的应用
CN102625797A (zh) 作为激酶抑制剂的取代杂环化合物及其使用方法
CN1726034A (zh) 亚甲基桥连的选择性雄激素受体调节剂及其应用方法
CN1468236A (zh) 可作为药物的新颖抗胆碱能制剂及其制备方法
CN1081460C (zh) 醛糖还原酶抑制剂用于制备减少与非心脏局部缺血有关的组织损伤的药物的用途
CN1041096C (zh) 氟化17β－取代的4－氮杂－5α－雄甾烷－3－酮衍生物
CN1094042A (zh) 关于苯并噻吩类的改进
TW200819444A (en) Benzoxazoles and oxazolopyridines being useful as janus kinases inhibitors
CN1271276A (zh) 经舌下或含服给药的控释药物
CN1726193A (zh) 杂环选择性雄激素受体调节剂及其使用方法
CN1360591A (zh) 具有麻醉剂活性的3α－羟基－3β－甲氧基甲基－21－杂环取代的类固醇
CN1126473A (zh) 化学组合物
CN1534026A (zh) 新型作为酪氨酸激酶抑制剂的稠合的喹唑啉衍生物
CZ280011B6 (cs) Opticky aktivní 5-(3-/(2S) nebo (2R)-exobicyklo /2.2.1/ hept-2-yloxy/-4-methoxyfenyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-on a způsob jeho přípravy
CN1780626A (zh) 双相性精神障碍和相关症状的治疗
CN1882606A (zh) 雌激素受体调节剂
EP2294068B1 (fr) DERIVES DE 1,3-DIHYDRO-2H-PYRROLO(3,2-b) PYRIDIN-2-ONE, LEUR PREPARATION ET LEURS APPLICATIONS EN THERAPEUTIQUE

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication