AU7634194A - Di- and tetra-hydrobenzo(F)quinolin-3-ones - Google Patents

Di- and tetra-hydrobenzo(F)quinolin-3-ones

Info

Publication number
AU7634194A
AU7634194A AU76341/94A AU7634194A AU7634194A AU 7634194 A AU7634194 A AU 7634194A AU 76341/94 A AU76341/94 A AU 76341/94A AU 7634194 A AU7634194 A AU 7634194A AU 7634194 A AU7634194 A AU 7634194A
Authority
AU
Australia
Prior art keywords
compound
anyone
quinolin
methyl
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU76341/94A
Other languages
English (en)
Inventor
Dennis Alan Holt
Dennis Shinji Yamashita
Hwa-Kwo Yen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU7634194A publication Critical patent/AU7634194A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU76341/94A 1993-08-20 1994-08-19 Di- and tetra-hydrobenzo(F)quinolin-3-ones Abandoned AU7634194A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9317314 1993-08-20
GB939317314A GB9317314D0 (en) 1993-08-20 1993-08-20 Compounds
PCT/US1994/009382 WO1995005821A1 (fr) 1993-08-20 1994-08-19 Di- et tetra-hydrobenzo[f]quinolein-3-ones

Publications (1)

Publication Number Publication Date
AU7634194A true AU7634194A (en) 1995-03-21

Family

ID=10740766

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76341/94A Abandoned AU7634194A (en) 1993-08-20 1994-08-19 Di- and tetra-hydrobenzo(F)quinolin-3-ones

Country Status (8)

Country Link
EP (1) EP0724440A4 (fr)
JP (1) JPH09501695A (fr)
CN (1) CN1133007A (fr)
AU (1) AU7634194A (fr)
CA (1) CA2169750A1 (fr)
GB (1) GB9317314D0 (fr)
WO (1) WO1995005821A1 (fr)
ZA (1) ZA946308B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037326A (en) * 1996-12-31 2000-03-14 Styczynski; Peter Reduction of hair growth
GB0129567D0 (en) 2001-12-11 2002-01-30 Trikon Technologies Ltd Diffusion barrier

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5198300A (en) * 1975-02-20 1976-08-30 Kanputoteshin oyobi sonoruijitaino seizoho
CA1110234A (fr) * 1978-01-18 1981-10-06 Hoffmann-La Roche Limited Acides 4-pyridone-3-carboxyliques et procede de fabrication
YU7087A (en) * 1986-01-23 1988-06-30 Hoffmann La Roche Process for obtaining benzazecine derivatives
US5250539A (en) * 1991-08-21 1993-10-05 Eli Lilly And Company Hexahydrobenzo[f]quinolinones
US5239075A (en) * 1991-08-21 1993-08-24 Eli Lilly And Company Process for the preparation of benzo (f) quinolinones

Also Published As

Publication number Publication date
EP0724440A4 (fr) 1996-11-20
ZA946308B (en) 1995-04-03
GB9317314D0 (en) 1993-10-06
CA2169750A1 (fr) 1995-03-02
EP0724440A1 (fr) 1996-08-07
WO1995005821A1 (fr) 1995-03-02
JPH09501695A (ja) 1997-02-18
CN1133007A (zh) 1996-10-09

Similar Documents

Publication Publication Date Title
EP0277002B1 (fr) Inhibiteurs de stéroide-5-alpha-réductase
CA1319362C (fr) Derives androstenedione substitues en 4, et procede pour leur preparation
JP2675418B2 (ja) 芳香族ステロイド５‐α‐レダクターゼ抑制剤
JPH02212499A (ja) ステロイド５‐α‐レダクターゼ抑制剤としてのホスホン酸置換芳香族ステロイド
JPH02225494A (ja) ステロイド５―α―レダクターゼ抑制剤としてのスルホン酸置換芳香族ステロイド
JPH03169890A (ja) ステロイド５―α―レダクターゼの抑制剤としての１１―ケトまたはヒドロキシ３，５―ジエンステロイド類
US5110939A (en) Intermediates in the preparation of steriod 5-alpha-reductase inhibitors
US5527806A (en) 17α and 17β substituted acyl 4 aza steroids
US5561124A (en) 17-α-acyl steroids which inhibit 5-α-reductase
EP0669931A1 (fr) Steroides 17-alpha-acyle inhibant 5-alpha-reductase
SI9300601A (en) Pharmaceutical active 17-alpha and 17-beta substituted acyl-3-carboxy-3,5-diene steroidal compounds
AU7634194A (en) Di- and tetra-hydrobenzo(F)quinolin-3-ones
US5237065A (en) Steroid 5-alpha-reductase inhibitors
EP0533796A1 (fr) DERIVES STEROIDES D'ACIDE TRIACETIQUE UTILISES COMME INHIBITEURS DE LA 5$g(a)-REDUCTASE
AP412A (en) 17a and 17B-Alkylketone-3-carboxyaromatic a ring steroidal compounds and pharmaceutical compositions containing these compounds.
EP0650358A1 (fr) 17-acyl-4-aza-steroide-3-one a titre d'inhibiteurs de 5-alpha-reductase
US5641877A (en) 17-α and 17-β substituted acyl-3-carboxy-3, 5-dienes and use in inhibiting 5-α-reductase
WO1995021185A1 (fr) STEROIDES A CYCLE A ACYLE 3-CARBOXY AROMATIQUE UTILISE COMME INHIBITEUR DE 5-α REDUCTASE
US5618806A (en) 17α and 17β-substituted estra-1,3,5(10)-triene-3-carbboxlic acid
US5683995A (en) 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
JPH06510982A (ja) 抗テストステロン化合物およびその使用方法
EP0755378A1 (fr) Composes de diazo-phenanthrenone inhibant la reductase 5-alpha