EP0724440A4 - Di- et tetra-hydrobenzo f]quinolein-3-ones - Google Patents

Di- et tetra-hydrobenzo f]quinolein-3-ones

Info

Publication number
EP0724440A4
EP0724440A4 EP94926534A EP94926534A EP0724440A4 EP 0724440 A4 EP0724440 A4 EP 0724440A4 EP 94926534 A EP94926534 A EP 94926534A EP 94926534 A EP94926534 A EP 94926534A EP 0724440 A4 EP0724440 A4 EP 0724440A4
Authority
EP
European Patent Office
Prior art keywords
hydrobenzo
quinolin
tetra
ones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94926534A
Other languages
German (de)
English (en)
Other versions
EP0724440A1 (fr
Inventor
Dennis Alan Holt
Dennis Shinji Yamashita
Hwa-Kwo Yen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0724440A1 publication Critical patent/EP0724440A1/fr
Publication of EP0724440A4 publication Critical patent/EP0724440A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EP94926534A 1993-08-20 1994-08-19 Di- et tetra-hydrobenzo f]quinolein-3-ones Withdrawn EP0724440A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9317314 1993-08-20
GB939317314A GB9317314D0 (en) 1993-08-20 1993-08-20 Compounds
PCT/US1994/009382 WO1995005821A1 (fr) 1993-08-20 1994-08-19 Di- et tetra-hydrobenzo[f]quinolein-3-ones

Publications (2)

Publication Number Publication Date
EP0724440A1 EP0724440A1 (fr) 1996-08-07
EP0724440A4 true EP0724440A4 (fr) 1996-11-20

Family

ID=10740766

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94926534A Withdrawn EP0724440A4 (fr) 1993-08-20 1994-08-19 Di- et tetra-hydrobenzo f]quinolein-3-ones

Country Status (8)

Country Link
EP (1) EP0724440A4 (fr)
JP (1) JPH09501695A (fr)
CN (1) CN1133007A (fr)
AU (1) AU7634194A (fr)
CA (1) CA2169750A1 (fr)
GB (1) GB9317314D0 (fr)
WO (1) WO1995005821A1 (fr)
ZA (1) ZA946308B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037326A (en) * 1996-12-31 2000-03-14 Styczynski; Peter Reduction of hair growth
GB0129567D0 (en) 2001-12-11 2002-01-30 Trikon Technologies Ltd Diffusion barrier

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0531026A1 (fr) * 1991-08-21 1993-03-10 Eli Lilly And Company Hexahydrobenzo(f)quinolinones comme inhibiteurs de 5-alpha-réductase
EP0532190A2 (fr) * 1991-08-21 1993-03-17 Eli Lilly And Company Benzo(f)quinolinones comme inhibiteurs de 5-alpha-réductase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5198300A (en) * 1975-02-20 1976-08-30 Kanputoteshin oyobi sonoruijitaino seizoho
CA1110234A (fr) * 1978-01-18 1981-10-06 Hoffmann-La Roche Limited Acides 4-pyridone-3-carboxyliques et procede de fabrication
DE3773950D1 (de) * 1986-01-23 1991-11-28 Hoffmann La Roche Benzazecin-derivate.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0531026A1 (fr) * 1991-08-21 1993-03-10 Eli Lilly And Company Hexahydrobenzo(f)quinolinones comme inhibiteurs de 5-alpha-réductase
EP0532190A2 (fr) * 1991-08-21 1993-03-17 Eli Lilly And Company Benzo(f)quinolinones comme inhibiteurs de 5-alpha-réductase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MICHEL BARON ET AL: "Hétérocycles à fonction quinone.III:Benzo[f]quinoléinediones-7,10,antitumoraux potentiels", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY CHIMICA THERAPEUTICA., vol. 18, no. 2, 1983, PARIS FR, pages 134 - 138, XP002014528 *
See also references of WO9505821A1 *

Also Published As

Publication number Publication date
EP0724440A1 (fr) 1996-08-07
AU7634194A (en) 1995-03-21
GB9317314D0 (en) 1993-10-06
CN1133007A (zh) 1996-10-09
JPH09501695A (ja) 1997-02-18
CA2169750A1 (fr) 1995-03-02
WO1995005821A1 (fr) 1995-03-02
ZA946308B (en) 1995-04-03

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