CN113208997A - Children moistening and skin-protecting shampoo and shower gel containing lactobacillus fermentation extract and preparation method thereof - Google Patents
Children moistening and skin-protecting shampoo and shower gel containing lactobacillus fermentation extract and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention provides a children moistening and skin-protecting shampoo and shower gel containing lactobacillus fermentation extract and a preparation method thereof, wherein the children moistening and skin-protecting shampoo and shower gel comprises the following raw materials in parts by weight: 0.1-4.6 parts of polyoxyethylene, 0.9-5.4 parts of polyalcohol, 10-23 parts of betaine, 0-7 parts of imidazole, 2-6 parts of glycerol, 0.3-0.5 part of sorbitol, 0.1-0.4 part of xylitol, 0.2-0.6 part of trehalose, 0.1-5 parts of lactobacillus fermentation product, 0.1-0.2 part of preservative and the balance of water, and the components are respectively stirred and heated for reaction, and the stirring speed and the stirring time are controlled.
Description
Technical Field
The invention relates to the technical field of preparation of children's washing and caring products, and in particular relates to a children's moistening and skin-caring shampoo and shower gel containing a lactobacillus fermentation extract and a preparation method thereof.
Background
The children washing and protecting cleaning products sold in the market at present are mainly prepared by anionic surfactants and conditioning formulas, and meanwhile, essence and spice components are added to cater to the market so as to improve the pleasant feeling of use. The stimulation of the anionic active agent to the skin can bring good cleaning/cleaning to people, but the skin barrier of rejuvenation of children can be damaged after long-term use, the essence and spice with the molecular weight of 100-200 can directly penetrate through the horny layer to permeate, the sebaceous membrane of the skin can be easily damaged, the skin of children is young and tender, eczema and the like are easy to occur, and the existing children cleaning and washing product has a good cleaning effect, but needs to be further improved in the aspects of safety, mildness and stability of raw materials, moisture preservation of the product, improvement of skin immunity and continuous skin care effect.
The patent of 'biological fermentation bath lotion and a preparation method thereof', application No. 201310156816.9 adopts pure natural fermented compound fermentation amino acid full-effect nutrient solution as a bath essence raw material, but the bacteriostatic activity of the fermentation liquor prepared from the used biological bacteria is poor;
in the patent of 'children's hair and body wash ', application No. 201711028700.1, coconut oil fatty alcohol hydroxyethyl sodium sulfonate and lauramide hydroxysultaine are used as active agents in order to meet the requirements of children's body wash, although the irritation is reduced to some extent, the requirements are still difficult to meet, the active agents are easily left on the surface of the skin to form an oil film, and the skin of children is tender and easy to be allergic.
Disclosure of Invention
In view of the above, the invention provides a children shampoo and shower gel containing lactic acid bacteria fermentation extract for moistening and caring skin and a preparation method thereof, and solves the above problems.
The technical scheme of the invention is realized as follows: a children shampoo and bath lotion containing lactobacillus fermentation extract for moistening and caring skin: the feed comprises the following raw materials in parts by weight: 0.1-4.6 parts of polyoxyethylene, 0.9-5.4 parts of polyalcohol, 10-23 parts of betaine, 0-7 parts of imidazole, 2-6 parts of glycerol, 0.3-0.5 part of sorbitol, 0.1-0.4 part of xylitol, 0.2-0.6 part of trehalose, 0.1-5 parts of lactic acid bacteria fermentation product, 0.1-0.2 part of preservative and 20-60 parts of water, wherein the polyalcohol is one of pentaerythritol, triethanolamine and glycerol, and the lactobacillus is lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1: 0.2-0.5: 0.8-1.2.
Further, the children shampoo and shower gel containing the lactic acid bacteria fermentation extract for moistening and protecting the skin comprises the following raw materials in parts by weight: 2.8 parts of polyoxyethylene, 2.5 parts of polyalcohol, 16 parts of betaine, 3 parts of imidazole, 4 parts of glycerol, 0.4 part of sorbitol, 0.2 part of xylitol, 0.4 part of trehalose, 3 parts of lactobacillus fermentation product, 0.1 part of preservative and the balance of water, wherein the lactobacillus is lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1:0.4: 1.
Further, the preparation method of the children shampoo and shower gel containing the lactic acid bacteria fermentation extract for moistening and protecting the skin comprises the following steps:
s1, mixing and stirring polyoxyethylene, polyhydric alcohol, betaine, imidazole, glycerol, sorbitol, xylitol and water uniformly according to the weight parts, heating to 50-80 ℃, and stirring for 30-50 min to obtain a solution I;
s2, adding the trehalose and lactic acid bacteria fermentation product into the solution I, adding into a reaction kettle, carrying out primary pressurization and heating to 25-38 ℃, carrying out reflux stirring reaction, carrying out pressure reduction, cooling, adding 2-4 volume times of water, carrying out secondary pressurization and heating to 28-40 ℃, carrying out stirring reaction, and cooling to obtain a solution II;
and S3, mixing the preservative into the solution II, and stirring and dissolving to obtain the children shampoo and shower gel.
Further, the stirring speed in the S1 is 100-300 rpm.
Further, the primary pressurization pressure in the step S2 is 33-50 Pa.
Further, the pressure of the secondary pressurization in the step S2 is 40-60 Pa.
Compared with the prior art, the invention has the beneficial effects that:
the shampoo and shower gel disclosed by the invention is safe and low in stimulation, is specially designed for children, has a mild formula which is similar to the pH value of skin, is good in antibacterial effect and less in stimulation, is added with various functional components and modified components of a nonionic surfactant, greatly reduces the stimulation caused by the surfactant, and is beneficial to establishing a healthy skin immune barrier. The lactobacillus reuteri, the lactobacillus casei and the streptococcus lactis in a specific proportion are mixed to form the functional components of the product, the raw materials are natural, the self-ecological environment is not broken, the skin cell growth factors can be activated, the beneficial growth environment for improving probiotics is established, and a good skin micro-ecological barrier is kept. By adopting specific process treatment, the raw material substances can be well mixed and stabilized, the moisturizing molecules and the soothing moisturizing molecules are fully mixed to promote skin absorption, and the skin of the young children is kept in a water-wet state all the time while the skin is cleaned.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
Example 1
A children's moistening skin-care shampoo-bath lotion containing lactobacillus fermentation extract comprises: the feed comprises the following raw materials in parts by weight: 0.1 part of polyoxyethylene, 0.9 part of pentaerythritol, 10 parts of betaine, 2 parts of glycerol, 0.3 part of sorbitol, 0.1 part of xylitol, 0.2 part of trehalose, 0.1 part of a lactic acid bacteria fermentation product, 0.1 part of a preservative and 20 parts of water, wherein the lactic acid bacteria are lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1:0.2: 0.8.
Example 2
A children's moistening skin-care shampoo-bath lotion containing lactobacillus fermentation extract comprises: the feed comprises the following raw materials in parts by weight: 4.6 parts of polyoxyethylene, 5.4 parts of triethanolamine, 23 parts of betaine, 7 parts of imidazole, 6 parts of glycerol, 0.5 part of sorbitol, 0.4 part of xylitol, 0.6 part of trehalose, 5 parts of a lactic acid bacteria fermentation product, 0.2 part of a preservative and 60 parts of water, wherein the lactic acid bacteria are lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1:0.5: 1.2.
Example 3
A children's moistening skin-care shampoo-bath lotion containing lactobacillus fermentation extract comprises: the feed comprises the following raw materials in parts by weight: 2.8 parts of polyoxyethylene, 2.5 parts of glycerol, 16 parts of betaine, 3 parts of imidazole, 4 parts of glycerol, 0.4 part of sorbitol, 0.2 part of xylitol, 0.4 part of trehalose, 3 parts of a lactic acid bacteria fermentation product, 0.1 part of a preservative and 40 parts of water, wherein the lactic acid bacteria are lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1:0.4: 1.
Examples 1-3 the following preparation methods were used:
s1, mixing and stirring polyoxyethylene, polyhydric alcohol, betaine, imidazole, glycerol, sorbitol, xylitol and water uniformly according to the parts by weight, heating to 50-80 ℃, and stirring for 30-50 min at the stirring speed of 100-300 rpm to obtain a solution I;
s2, adding the trehalose and lactic acid bacteria fermentation product into the solution I, adding the solution I into a reaction kettle, carrying out primary pressurization and heating to 25-38 ℃ at a pressure of 33-50 Pa, carrying out reflux stirring reaction, carrying out reduced pressure, cooling, adding 3-volume-times water, carrying out secondary pressurization and heating to 28-40 ℃ at a pressure of 40-60 Pa, carrying out stirring reaction, and cooling to obtain a solution II;
and S3, mixing the preservative into the solution II, and stirring and dissolving to obtain the children shampoo and shower gel.
Example 4
The difference between the embodiment and the embodiment 3 is that the preparation method of the children's skin-friendly shampoo and shower gel containing the lactobacillus fermentation extract comprises the following steps:
s1, mixing and stirring polyoxyethylene, polyhydric alcohol, betaine, imidazole, glycerol, sorbitol, xylitol and water uniformly according to the parts by weight, heating to 50-80 ℃, and stirring for 30-50 min at the stirring speed of 100-300 rpm to obtain a solution I;
s2, adding the trehalose and lactic acid bacteria fermentation product into the solution I, adding the solution I into a reaction kettle, carrying out primary pressurization and heating to 25-38 ℃ at a pressure of 33-50 Pa, carrying out reflux stirring reaction, carrying out reduced pressure, cooling, adding 2-volume-times water, carrying out secondary pressurization and heating to 28-40 ℃ at a pressure of 40-60 Pa, carrying out stirring reaction, and cooling to obtain a solution II;
and S3, mixing the preservative into the solution II, and stirring and dissolving to obtain the children shampoo and shower gel.
Example 5
The difference between the embodiment and the embodiment 3 is that the preparation method of the children's skin-friendly shampoo and shower gel containing the lactobacillus fermentation extract comprises the following steps:
s1, mixing and stirring polyoxyethylene, polyhydric alcohol, betaine, imidazole, glycerol, sorbitol, xylitol and water uniformly according to the parts by weight, heating to 50-80 ℃, and stirring for 30-50 min at the stirring speed of 100-300 rpm to obtain a solution I;
s2, adding the trehalose and lactic acid bacteria fermentation product into the solution I, adding the solution I into a reaction kettle, carrying out primary pressurization and heating to 25-38 ℃ at a pressure of 33-50 Pa, carrying out reflux stirring reaction, carrying out reduced pressure, cooling, adding 4-volume-times water, carrying out secondary pressurization and heating to 28-40 ℃ at a pressure of 40-60 Pa, carrying out stirring reaction, and cooling to obtain a solution II;
and S3, mixing the preservative into the solution II, and stirring and dissolving to obtain the children shampoo and shower gel.
Comparative example 1
The difference between the comparative example and the example 3 is that the children moistening and skin-protecting shampoo and shower gel containing the lactobacillus fermentation extract comprises the following raw materials in parts by weight: 5 parts of polyoxyethylene, 6 parts of polyhydric alcohol, 25 parts of betaine, 10 parts of imidazole, 8 parts of glycerol, 0.8 part of sorbitol, 0.5 part of xylitol, 0.8 part of trehalose, 6 parts of lactobacillus fermentation product, 0.4 part of preservative and 20 parts of water.
Comparative example 2
The difference between the comparative example and the example 3 is that the children moistening and skin-protecting shampoo and shower gel containing the lactobacillus fermentation extract comprises the following raw materials in parts by weight: the feed comprises the following raw materials in parts by weight: 2.8 parts of polyoxyethylene, 2.5 parts of polyhydric alcohol, 16 parts of betaine, 3 parts of imidazole, 4 parts of glycerol, 0.8 part of sorbitol, 0.5 part of xylitol, 0.8 part of trehalose, 6 parts of lactobacillus fermentation product, 0.4 part of preservative and 50 parts of water.
Comparative example 3
This comparative example differs from example 3 in that the lactic acid bacteria are Lactobacillus reuteri, Lactobacillus casei, Streptococcus lactis in a weight ratio of 1:0.7: 1.5.
Firstly, testing bacteriostatic effect
Filter paper sheet experiment: selecting 2 colonies with moderate size for 24-48h, aseptically adding 9ml sterile normal saline, stirring with magnetic stirrer for 1min to obtain uniform colonies with 3-5 × 106-107cfu·ml-1The suspension liquid is reserved; the filter paper with the thickness of 1.5mm is beaten into a circular sheet with the diameter of 6mm, the filter paper sheet is wrapped, the filter paper sheet is soaked in the shampoo and bath lotion samples of examples 1-5 and comparative examples 1-3 for 1min respectively, the filter paper sheet is taken out and lightly pasted on a flat plate, then the flat plate is placed upside down in a thermostat, each bacterium is cultured for 24h according to the optimum temperature, the diameter mm of each inhibition zone is measured by a micrometer, and the number of the used bacterium suspension is counted by being poured on the flat plate.
The test data was analyzed as follows: (unit: mm)
As can be seen from the above table, the shampoo and bath cream of the present invention has a certain bacteriostatic effect, wherein the better bacteriostatic effect is the comparison between example 3, examples 1 to 5 and comparative examples 1 to 3, which shows that the formula of the present invention has better raw material selection and scientific proportioning, and the bacteriostatic effect of the present invention can be achieved only in a proper proportion.
Second, irritation test
The method comprises the following steps of carrying out irritation test evaluation on the shampoo and shower gel of the examples 1-5 and the comparative examples 1-3 according to the acute eye irritation in the technical Specification for safety of cosmetics, and specifically comprising the following steps of:
1. the test substance: shampoo baths prepared in examples 1 to 5 and comparative examples 1 to 3.
2. Test animals: 24 healthy white rabbits were randomly divided into 8 groups, each group had 3 rabbits, had normal eyes, no eye irritation symptom, bruised ginger defect, and conjunctival injury problem.
3. The test steps are as follows: the lower eyelid of one side of the eye of the rabbit is pulled open, 0.1ml of the test object is dripped into the conjunctival sac, and the upper eyelid and the lower eyelid are passively closed for 1 s.
4. And (3) clinical examination: observing animal cornea, iris and conjunctiva 1, 5 and 24h after dropping the test object, if no irritation response appears 24h, terminating the test, recording the integral of eye irritation response according to a scoring standard in each test, evaluating the average value and recovery time of the irritation response integral of the animal cornea, iris or conjunctiva at the observation time point of 1, 5 and 24h respectively after the test object, calculating the average eye irritation response integral, and grading and judging the irritation intensity of the test object to eyes according to the eye irritation response, wherein the results are as follows:
| grading of the reaction | Effect of reaction | Integration |
| Has no irritation | Cornea, iris and conjunctiva are normal without discomfort | 0 |
| Micro-stimulation property | Corneal congestion | 1-2 |
| Light irritation | Corneal hyperemia and conjunctival edema | 3-5 |
| Irritation property | Corneal opacification | 6-8 |
The average integration of the ocular irritation response of the test subjects is as follows:
as can be seen from the above table, the shampoo and bath lotion of examples 1 to 5 of the present invention has no irritation to the cornea, iris and conjunctiva of animals, while the conjunctiva of comparative examples 1 to 3 has corneal hyperemia after about 1 hour, but decreases to 0 after 24 hours, and b has less irritation, and has better applicability to children and the following children of the younger age.
Third, determination of moisturizing and skin-moistening efficacy
90 subjects (45 men and women) aged 0-10 are divided into 9 groups at random, each group has 10 persons, the experimental time is 12h, the temperature is 25 +/-2 ℃, and the humidity is 40-50%. The test sites (4 cm. times.4 cm) were marked on the inside of the left and right arms of each volunteer, respectively, and the test samples and controls were randomly distributed on the left and right arms. Each tested part is smeared with 0.05mL of sample, the moisture content of the skin in a test sample area and a control area in 5 time periods is measured by a multifunctional skin tester after smearing, the moisture content of the original skin of all experimenters is 62-67%, and the following data is an average value.
| Time (h) | 2 | 8 | 10 | 12 |
| Example 1 | 88.4 | 85.0 | 78.3 | 72.4 |
| Example 2 | 88.3 | 86.9 | 77.1 | 73.1 |
| Example 3 | 89.2 | 88.4 | 79.1 | 74.5 |
| Example 4 | 88.3 | 83.3 | 75.9 | 71.2 |
| Example 5 | 82.1 | 83.5 | 75.3 | 70.6 |
| Comparative example 1 | 78.9 | 75.9 | 70.3 | 69.6 |
| Comparative example 2 | 78.2 | 77.1 | 70.1 | 68.1 |
| Comparative example 3 | 78.1 | 75.7 | 71.3 | 69.7 |
| Is commercially available | 73.8 | 72.1 | 70.2 | 68.5 |
Therefore, the shampoo and shower gel prepared by the invention is specially designed for children, has a mild formula which is close to the pH value of skin, has little stimulation, is added with various functional components, adopts specific process treatment, can well mix and stabilize various raw materials, fully mixes moisturizing molecules and soothing moisturizing molecules to promote skin absorption, and keeps young skin of children in a moisturizing state all the time while cleaning the skin.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (6)
1. A children's moistening skin-care shampoo and shower gel containing lactic acid bacteria fermentation extract is characterized in that: the feed comprises the following raw materials in parts by weight: 0.1-4.6 parts of polyoxyethylene, 0.9-5.4 parts of polyalcohol, 10-23 parts of betaine, 0-7 parts of imidazole, 2-6 parts of glycerol, 0.3-0.5 part of sorbitol, 0.1-0.4 part of xylitol, 0.2-0.6 part of trehalose, 0.1-5 parts of lactic acid bacteria fermentation product, 0.1-0.2 part of preservative and 20-60 parts of water, wherein the polyalcohol is one of pentaerythritol, triethanolamine and glycerol, and the lactobacillus is lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1: 0.2-0.5: 0.8-1.2.
2. The children's skin-friendly shampoo and shower gel containing the lactic acid bacteria fermentation extract as claimed in claim 1, wherein: the feed comprises the following raw materials in parts by weight: 2.8 parts of polyoxyethylene, 2.5 parts of polyhydric alcohol, 16 parts of betaine, 3 parts of imidazole, 4 parts of glycerol, 0.4 part of sorbitol, 0.2 part of xylitol, 0.4 part of trehalose, 3 parts of a lactic acid bacteria fermentation product, 0.1 part of a preservative and 40 parts of water, wherein the lactic acid bacteria are lactobacillus reuteri, lactobacillus casei and streptococcus lactis in a weight ratio of 1:0.4: 1.
3. The method for preparing the children's skin-friendly shampoo and shower gel containing the lactobacillus fermentation extract as claimed in claim 1, wherein the method comprises the following steps: the method comprises the following steps:
s1, mixing and stirring polyoxyethylene, polyhydric alcohol, betaine, imidazole, glycerol, sorbitol, xylitol and water uniformly according to the weight parts, heating to 50-80 ℃, and stirring for 30-50 min to obtain a solution I;
s2, adding the trehalose and lactic acid bacteria fermentation product into the solution I, adding into a reaction kettle, carrying out primary pressurization and heating to 25-38 ℃, carrying out reflux stirring reaction, carrying out pressure reduction, cooling, adding 2-4 volume times of water, carrying out secondary pressurization and heating to 28-40 ℃, carrying out stirring reaction, and cooling to obtain a solution II;
and S3, mixing the preservative into the solution II, and stirring and dissolving to obtain the children shampoo and shower gel.
4. The method for preparing the children's skin-friendly shampoo and shower gel containing the lactobacillus fermentation extract as claimed in claim 3, wherein the method comprises the following steps: the stirring speed in the S1 is 100-300 rpm.
5. The method for preparing the children's skin-friendly shampoo and shower gel containing the lactobacillus fermentation extract as claimed in claim 3, wherein the method comprises the following steps: and the pressure of primary pressurization in the S2 is 33-50 Pa.
6. The method for preparing the children's skin-friendly shampoo and shower gel containing the lactobacillus fermentation extract as claimed in claim 3, wherein the method comprises the following steps: and the pressure of secondary pressurization in the S2 is 40-60 Pa.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110416266.4A CN113208997A (en) | 2021-04-19 | 2021-04-19 | Children moistening and skin-protecting shampoo and shower gel containing lactobacillus fermentation extract and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110416266.4A CN113208997A (en) | 2021-04-19 | 2021-04-19 | Children moistening and skin-protecting shampoo and shower gel containing lactobacillus fermentation extract and preparation method thereof |
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| CN113208997A true CN113208997A (en) | 2021-08-06 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116211765A (en) * | 2023-02-13 | 2023-06-06 | 广州宋清科技有限公司 | Anti-hair loss shampoo and preparation method thereof |
-
2021
- 2021-04-19 CN CN202110416266.4A patent/CN113208997A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116211765A (en) * | 2023-02-13 | 2023-06-06 | 广州宋清科技有限公司 | Anti-hair loss shampoo and preparation method thereof |
| CN116211765B (en) * | 2023-02-13 | 2023-10-10 | 浙江领康生物科技有限公司 | Anti-hair loss shampoo and preparation method thereof |
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Application publication date: 20210806 |
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