CN1130558C - 混合方法 - Google Patents

混合方法 Download PDF

Info

Publication number
CN1130558C
CN1130558C CN99802180A CN99802180A CN1130558C CN 1130558 C CN1130558 C CN 1130558C CN 99802180 A CN99802180 A CN 99802180A CN 99802180 A CN99802180 A CN 99802180A CN 1130558 C CN1130558 C CN 1130558C
Authority
CN
China
Prior art keywords
mixing
sample
cavity
liquid
walls
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN99802180A
Other languages
English (en)
Chinese (zh)
Other versions
CN1288517A (zh
Inventor
约翰尼·斯文松
贝蒂尔·尼尔松
珀·乌尔松
拉尔斯·荣松
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hemocue AB
Original Assignee
Hemocue AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemocue AB filed Critical Hemocue AB
Publication of CN1288517A publication Critical patent/CN1288517A/zh
Application granted granted Critical
Publication of CN1130558C publication Critical patent/CN1130558C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0325—Cells for testing reactions, e.g. containing reagents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0325—Cells for testing reactions, e.g. containing reagents
    • G01N2021/0328—Arrangement of two or more cells having different functions for the measurement of reactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/11—Filling or emptying of cuvettes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/827—Lectins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Processing Of Solid Wastes (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
CN99802180A 1998-01-14 1999-01-14 混合方法 Expired - Fee Related CN1130558C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE98000706 1998-01-14
SE9800070A SE9800070D0 (sv) 1998-01-14 1998-01-14 Blandningsmetod

Publications (2)

Publication Number Publication Date
CN1288517A CN1288517A (zh) 2001-03-21
CN1130558C true CN1130558C (zh) 2003-12-10

Family

ID=20409855

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99802180A Expired - Fee Related CN1130558C (zh) 1998-01-14 1999-01-14 混合方法

Country Status (11)

Country Link
US (1) US6468807B1 (enExample)
EP (1) EP1055112B1 (enExample)
JP (2) JP4502504B2 (enExample)
CN (1) CN1130558C (enExample)
AT (1) ATE386930T1 (enExample)
AU (1) AU2195699A (enExample)
DE (1) DE69938170T2 (enExample)
DK (1) DK1055112T3 (enExample)
ES (1) ES2299239T3 (enExample)
SE (1) SE9800070D0 (enExample)
WO (1) WO1999036765A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19933458B4 (de) * 1999-07-15 2015-08-20 Eppendorf Ag Einrichtungen und Systeme zum Handhaben von Flüssigkeitsproben
JP3621617B2 (ja) * 2000-01-21 2005-02-16 ブラザー工業株式会社 グルコース濃度測定用のキャピラリー装置、グルコース濃度の非侵襲的モニター方法及び血糖値の非侵襲的モニター方法
US7029628B2 (en) 2000-12-28 2006-04-18 Stat-Chem Inc. Portable co-oximeter
CA2523124A1 (en) * 2003-03-20 2004-10-07 Gary D. Niehaus Self-contained assay device for rapid detection of biohazardous agents
CN1957254B (zh) 2004-04-07 2012-01-25 沃德劳有限合伙公司 用于分析生物流体的可置换腔
SE528697C2 (sv) * 2005-03-11 2007-01-30 Hemocue Ab Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov
SE529643C3 (sv) * 2005-07-08 2007-11-06 Hemocue Ab En kuvett och en metod och ett verktyg för tillverkning därav
US7731901B2 (en) 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
WO2008002462A2 (en) * 2006-06-23 2008-01-03 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
EP2056109B1 (en) 2006-08-21 2011-06-15 Panasonic Corporation Measuring device, measuring apparatus measuring method
WO2009124186A1 (en) * 2008-04-02 2009-10-08 Abbott Point Of Care, Inc. Self-calibrating gradient dilution in a constituent assay and gradient dilution apparatus performed in a thin film sample
US7947492B2 (en) * 2008-08-20 2011-05-24 Northeastern Ohio Universities College Of Medicine Device improving the detection of a ligand
JP5551763B2 (ja) 2009-04-23 2014-07-16 コーニンクレッカ フィリップス エヌ ヴェ ゼロデッドボリュームを有するミキサ
EP2512647A2 (en) 2009-12-18 2012-10-24 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
US10114020B2 (en) 2010-10-11 2018-10-30 Mbio Diagnostics, Inc. System and device for analyzing a fluidic sample
EP2658653B1 (en) 2010-12-30 2015-03-04 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge with sample handling portion and analysis chamber portion
US9157903B2 (en) * 2011-02-25 2015-10-13 Honeywell International Inc. Microfluidic separation of plasma for colormetric assay
WO2013028980A1 (en) 2011-08-24 2013-02-28 Abbott Point Of Care, Inc. Biologic fluid sample analysis cartridge
KR102090934B1 (ko) 2012-01-09 2020-03-19 퍼킨엘머 헬스 사이언시즈, 아이엔씨. 마이크로유체 반응기 시스템
US9739714B2 (en) 2012-10-29 2017-08-22 Mbio Diagnostics, Inc. Particle identification system, cartridge and associated methods
JP6498125B2 (ja) 2012-12-21 2019-04-10 マイクロニクス， インコーポレイテッド 流体回路および関連する製造方法
KR20150097764A (ko) 2012-12-21 2015-08-26 마이크로닉스 인코포레이티드. 휴대형 형광 검출 시스템 및 미량분석 카트리지
EP3549674B1 (en) 2012-12-21 2020-08-12 PerkinElmer Health Sciences, Inc. Low elasticity films for microfluidic use
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
JP6484222B2 (ja) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド 核酸の調製および分析のためのデバイス
AU2014262710B2 (en) 2013-05-07 2019-09-12 Revvity Health Sciences, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
GB2555403B (en) * 2016-10-24 2021-03-24 Entia Ltd A Cuvette
EP3669178B1 (en) 2017-08-17 2023-07-19 Abbott Point Of Care Inc Systems for performing optical and electrochemical assays
US11067526B2 (en) 2017-08-17 2021-07-20 Abbott Point Of Care Inc. Devices, systems, and methods for performing optical and electrochemical assays
GB2607337B (en) 2021-06-04 2025-04-02 Entia Ltd A cuvette
GB2616840A (en) 2022-03-18 2023-09-27 Entia Ltd A cuvette for analysing biological samples
GB2616667A (en) 2022-03-18 2023-09-20 Entia Ltd A composition for coating a cuvette and a method of making a composition for coating a cuvette
GB2616668A (en) 2022-03-18 2023-09-20 Entia Ltd A method of obtaining an image of a biological sample in a cuvette

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE107783C (enExample)
US3898982A (en) * 1972-11-13 1975-08-12 Jintan Terumo Co Capillary tube for blood examination
DD107783A1 (enExample) * 1973-12-03 1974-08-12
JPS51114767A (en) * 1975-03-31 1976-10-08 Fujirebio Inc Vibrator
SE399768B (sv) * 1975-09-29 1978-02-27 Lilja Jan E Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet
DE2966763D1 (de) * 1979-10-16 1984-04-12 Stocker Winfried Microanalytic device
EP0075605B1 (de) * 1981-09-25 1987-01-21 Winfried Dr. med. Stöcker Vorrichtung für photometrische Analysen
SE452512B (sv) * 1984-09-11 1987-11-30 Biolabimex Ab Forfarande for minskning av de elektrostatiska krafterna, t ex ytspenning, i en vetska , i synnerhet blod eller blodlosning
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
DE3650524T2 (de) * 1985-09-30 1996-11-21 Molecular Devices Corp Photometrisches Vielortmesssystem mit einer Quelle
SE8601528D0 (sv) 1986-04-07 1986-04-07 Leo Ab Mixing apparatus and method
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
CA1315181C (en) * 1987-04-13 1993-03-30 Joel M. Blatt Test strip device with volume metering capillary gap
JPH0217426A (ja) * 1988-07-05 1990-01-22 Kiyouseki Seihin Gijutsu Kenkyusho:Kk 液体試料用の分析セル
US5286454A (en) * 1989-04-26 1994-02-15 Nilsson Sven Erik Cuvette
JP2832117B2 (ja) * 1991-11-29 1998-12-02 キヤノン株式会社 サンプル測定デバイス及びサンプル測定システム
SE504193C2 (sv) 1995-04-21 1996-12-02 Hemocue Ab Kapillär mikrokyvett
US6001307A (en) * 1996-04-26 1999-12-14 Kyoto Daiichi Kagaku Co., Ltd. Device for analyzing a sample

Also Published As

Publication number Publication date
CN1288517A (zh) 2001-03-21
EP1055112A1 (en) 2000-11-29
JP2002509247A (ja) 2002-03-26
DE69938170T2 (de) 2009-02-26
DK1055112T3 (da) 2008-04-14
DE69938170D1 (de) 2008-04-03
JP4502504B2 (ja) 2010-07-14
SE9800070D0 (sv) 1998-01-14
ES2299239T3 (es) 2008-05-16
AU2195699A (en) 1999-08-02
JP2009053201A (ja) 2009-03-12
WO1999036765A1 (en) 1999-07-22
ATE386930T1 (de) 2008-03-15
JP4491032B2 (ja) 2010-06-30
EP1055112B1 (en) 2008-02-20
US6468807B1 (en) 2002-10-22

Similar Documents

Publication Publication Date Title
CN1130558C (zh) 混合方法
AU613623B2 (en) Element and method for performing biological assays accurately, rapidly and simply
CA2737892C (en) Apparatus and methods for analyte measurement and immunoassay
US6007775A (en) Multiple analyte diffusion based chemical sensor
JP4491010B2 (ja) 光度計
US10058867B2 (en) Sample metering device and assay device with integrated sample dilution
CN105874320A (zh) 用于纳米流体生物传感器的气体排空系统
CN114405568A (zh) 一种自驱式微流控芯片
JPH0618527A (ja) 検体測定装置

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20031210

Termination date: 20160114