CN112739816B - 用于激活和扩增嵌合抗原受体-修饰的免疫细胞的蛋白l - Google Patents
用于激活和扩增嵌合抗原受体-修饰的免疫细胞的蛋白lInfo
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- CN112739816B CN112739816B CN201980061485.6A CN201980061485A CN112739816B CN 112739816 B CN112739816 B CN 112739816B CN 201980061485 A CN201980061485 A CN 201980061485A CN 112739816 B CN112739816 B CN 112739816B
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- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862733291P | 2018-09-19 | 2018-09-19 | |
| US62/733,291 | 2018-09-19 | ||
| PCT/US2019/051832 WO2020061256A1 (en) | 2018-09-19 | 2019-09-19 | Protein l for activation and expansion of chimeric antigen receptor-modified immune cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112739816A CN112739816A (zh) | 2021-04-30 |
| CN112739816B true CN112739816B (zh) | 2025-09-12 |
Family
ID=68085017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980061485.6A Active CN112739816B (zh) | 2018-09-19 | 2019-09-19 | 用于激活和扩增嵌合抗原受体-修饰的免疫细胞的蛋白l |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12533414B2 (https=) |
| EP (1) | EP3853351A1 (https=) |
| JP (2) | JP7716976B2 (https=) |
| KR (1) | KR20210061397A (https=) |
| CN (1) | CN112739816B (https=) |
| AU (1) | AU2019345052B2 (https=) |
| CA (1) | CA3110706A1 (https=) |
| IL (1) | IL281413B2 (https=) |
| SG (1) | SG11202102654UA (https=) |
| WO (1) | WO2020061256A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021255189A1 (en) * | 2020-06-17 | 2021-12-23 | Tiziana Life Sciences, Plc | Compositions and methods for augmenting chimeric antigen receptor (car) t cell therapies |
| MX2023011927A (es) | 2021-04-07 | 2023-10-23 | Century Therapeutics Inc | Composiciones y metodos para la generacion de linfocitos t gamma-delta a partir de celulas madre pluripotentes inducidas. |
| US20220333074A1 (en) | 2021-04-07 | 2022-10-20 | Century Therapeutics, Inc. | Compositions and Methods for Generating Alpha-Beta T Cells from Induced Pluripotent Stem Cells |
| JP7738826B2 (ja) * | 2021-10-29 | 2025-09-16 | 東ソー株式会社 | 遺伝子改変t細胞の製造方法 |
| CN113980901B (zh) * | 2021-12-28 | 2022-06-17 | 上海惠盾因泰生物科技有限公司 | 一种制备高纯度的成熟人树突状细胞的方法及应用 |
| JPWO2024242080A1 (https=) * | 2023-05-22 | 2024-11-28 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102816734A (zh) * | 2012-05-09 | 2012-12-12 | 阮润生 | 一种肿瘤抗原特异性t细胞的获取方法 |
| WO2018102795A2 (en) * | 2016-12-02 | 2018-06-07 | University Of Southern California | Synthetic immune receptors and methods of use thereof |
| CN115516084A (zh) * | 2020-03-31 | 2022-12-23 | 国立大学法人京都大学 | T细胞祖细胞的制造方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL144339A0 (en) | 1999-01-28 | 2002-05-23 | Palmetto Health Alliance | A cell line containing gamma delta lymphocytes and pharmaceutical compositions containing the same |
| US20030235908A1 (en) | 2000-02-24 | 2003-12-25 | Xcyte Therapies, Inc. | Activation and expansion of cells |
| EP2216342B1 (en) | 2003-07-31 | 2015-04-22 | Immunomedics, Inc. | Anti-CD19 antibodies |
| AU2006298188B2 (en) * | 2005-09-30 | 2012-03-15 | Takara Bio Inc. | Method for production of T cell population |
| WO2008111430A1 (ja) | 2007-03-09 | 2008-09-18 | Takara Bio Inc. | γδT細胞集団の製造方法 |
| CN102046780A (zh) | 2008-03-27 | 2011-05-04 | 宝生物工程株式会社 | 转染的细胞的生产方法 |
| KR101720961B1 (ko) | 2009-02-27 | 2017-03-29 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 다능성 세포의 분화 |
| SG10201608307WA (en) | 2012-04-20 | 2016-11-29 | Emergent Product Dev Seattle | Cd3 binding polypeptides |
| AU2013327136A1 (en) | 2012-10-02 | 2015-04-16 | Memorial Sloan-Kettering Cancer Center | Compositions and methods for immunotherapy |
| MX2017012939A (es) * | 2015-04-08 | 2018-05-22 | Novartis Ag | Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19. |
| EP3352571A1 (en) | 2015-09-25 | 2018-08-01 | Flechsig Patent Company LLC | Novel plant protecting compositions and uses thereof |
| CN108431211B (zh) | 2015-10-20 | 2026-03-24 | 富士胶片细胞动力公司 | 通过遗传编程的多谱系造血前体细胞产生 |
| MX2018005274A (es) | 2015-10-30 | 2019-09-19 | The Regents Of The Universtiy Of California | Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t. |
| CA3003152A1 (en) * | 2015-11-04 | 2017-05-11 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
| MY185961A (en) | 2015-11-04 | 2021-06-14 | Univ Pennsylvania | Methods and compositions for gene editing in hematopoietic stem cells |
| RU2021107053A (ru) * | 2016-03-16 | 2021-08-24 | Нексиммьюн, Инк. | Получение антигенспецифических t-клеток |
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2019
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| CN102816734A (zh) * | 2012-05-09 | 2012-12-12 | 阮润生 | 一种肿瘤抗原特异性t细胞的获取方法 |
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| JP7716976B2 (ja) | 2025-08-01 |
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| CA3110706A1 (en) | 2020-03-26 |
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| EP3853351A1 (en) | 2021-07-28 |
| WO2020061256A1 (en) | 2020-03-26 |
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| US20220031744A1 (en) | 2022-02-03 |
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| JP2025106298A (ja) | 2025-07-15 |
| US12533414B2 (en) | 2026-01-27 |
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