CN112638852A - 双芴化合物的结晶体 - Google Patents
双芴化合物的结晶体 Download PDFInfo
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- CN112638852A CN112638852A CN201980056020.1A CN201980056020A CN112638852A CN 112638852 A CN112638852 A CN 112638852A CN 201980056020 A CN201980056020 A CN 201980056020A CN 112638852 A CN112638852 A CN 112638852A
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- 239000013078 crystal Substances 0.000 title claims abstract description 160
- 150000001875 compounds Chemical class 0.000 title description 37
- 238000000113 differential scanning calorimetry Methods 0.000 claims abstract description 31
- HBTONAMIPDVQRI-UHFFFAOYSA-N 2-[4-[9-[4-(2-hydroxyethoxy)-3-phenylphenyl]fluoren-9-yl]-2-phenylphenoxy]ethanol Chemical compound OCCOC1=CC=C(C2(C3=CC=CC=C3C3=CC=CC=C32)C=2C=C(C(OCCO)=CC=2)C=2C=CC=CC=2)C=C1C1=CC=CC=C1 HBTONAMIPDVQRI-UHFFFAOYSA-N 0.000 claims abstract description 28
- 238000004519 manufacturing process Methods 0.000 claims abstract description 18
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- PBMQHMJOBMZOGU-UHFFFAOYSA-N 4-(9h-fluoren-1-yl)-2-phenylphenol Chemical compound OC1=CC=C(C=2C=3CC4=CC=CC=C4C=3C=CC=2)C=C1C1=CC=CC=C1 PBMQHMJOBMZOGU-UHFFFAOYSA-N 0.000 description 2
- YWFPGFJLYRKYJZ-UHFFFAOYSA-N 9,9-bis(4-hydroxyphenyl)fluorene Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C2=CC=CC=C21 YWFPGFJLYRKYJZ-UHFFFAOYSA-N 0.000 description 2
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- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 2
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 2
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- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 description 2
- 150000001356 alkyl thiols Chemical class 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 239000003426 co-catalyst Substances 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
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- 239000011549 crystallization solution Substances 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 238000004821 distillation Methods 0.000 description 2
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethanethiol Chemical compound CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 2
- 125000003983 fluorenyl group Chemical group C1(=CC=CC=2C3=CC=CC=C3CC12)* 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000004811 liquid chromatography Methods 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
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- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 description 2
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- JRRDISHSXWGFRF-UHFFFAOYSA-N 1-[2-(2-ethoxyethoxy)ethoxy]-2-methoxyethane Chemical compound CCOCCOCCOCCOC JRRDISHSXWGFRF-UHFFFAOYSA-N 0.000 description 1
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- AIFZYIWZIDCFDV-UHFFFAOYSA-N 2-[4-(9h-fluoren-1-yl)-2-phenylphenoxy]ethanol Chemical compound OCCOC1=CC=C(C=2C3=C(C4=CC=CC=C4C3)C=CC=2)C=C1C1=CC=CC=C1 AIFZYIWZIDCFDV-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
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- 229910016523 CuKa Inorganic materials 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 1
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- 150000001298 alcohols Chemical class 0.000 description 1
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- 239000003513 alkali Substances 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
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- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018-174723 | 2018-09-19 | ||
| JP2018174723 | 2018-09-19 | ||
| PCT/JP2019/036374 WO2020059710A1 (ja) | 2018-09-19 | 2019-09-17 | ビスフルオレン化合物の結晶体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112638852A true CN112638852A (zh) | 2021-04-09 |
Family
ID=69887098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980056020.1A Pending CN112638852A (zh) | 2018-09-19 | 2019-09-17 | 双芴化合物的结晶体 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP7379770B2 (ja) |
| KR (1) | KR20210063323A (ja) |
| CN (1) | CN112638852A (ja) |
| TW (1) | TWI810366B (ja) |
| WO (1) | WO2020059710A1 (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114890877A (zh) * | 2022-01-28 | 2022-08-12 | 江苏永星化工股份有限公司 | 9,9-二[3-苯基-4-(2-羟基乙氧基)苯基]芴及其制备方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101657406A (zh) * | 2007-02-15 | 2010-02-24 | 田冈化学工业株式会社 | 芴衍生物的结晶多形体及其制造方法 |
| CN104230671A (zh) * | 2014-07-18 | 2014-12-24 | 宿迁市永星化工有限公司 | 9,9-双(6-羟基萘-2-基)芴的溶剂合物晶体及其制备 |
| CN106349030A (zh) * | 2015-07-17 | 2017-01-25 | 宿迁市永星化工有限公司 | 高堆积密度9,9-二[3-苯基-4-(2-羟基乙氧基)苯基]芴晶体的制备 |
| JP2017200901A (ja) * | 2015-07-21 | 2017-11-09 | 田岡化学工業株式会社 | フルオレン骨格を有するアルコールの結晶およびその製造方法 |
| CN107848931A (zh) * | 2015-07-08 | 2018-03-27 | 田冈化学工业株式会社 | 具有芴骨架的醇的晶体及其制造方法 |
| JP2018048086A (ja) * | 2016-09-21 | 2018-03-29 | 田岡化学工業株式会社 | フルオレン骨格を有するアルコール化合物の結晶およびその製造方法 |
| JP2018076245A (ja) * | 2016-11-08 | 2018-05-17 | 田岡化学工業株式会社 | フルオレン骨格を有するジヒドロキシ化合物の精製方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001206863A (ja) | 2000-01-25 | 2001-07-31 | Osaka Gas Co Ltd | フルオレン化合物及びその製造方法 |
| JP5285561B2 (ja) | 2009-09-30 | 2013-09-11 | 大阪瓦斯株式会社 | フルオレン骨格を有するポリエステル樹脂 |
| JP5437106B2 (ja) | 2010-02-19 | 2014-03-12 | 大阪ガスケミカル株式会社 | フルオレン骨格を有するポリエステル樹脂 |
-
2019
- 2019-09-17 WO PCT/JP2019/036374 patent/WO2020059710A1/ja active Application Filing
- 2019-09-17 KR KR1020217006589A patent/KR20210063323A/ko unknown
- 2019-09-17 CN CN201980056020.1A patent/CN112638852A/zh active Pending
- 2019-09-17 JP JP2020548514A patent/JP7379770B2/ja active Active
- 2019-09-18 TW TW108133601A patent/TWI810366B/zh active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101657406A (zh) * | 2007-02-15 | 2010-02-24 | 田冈化学工业株式会社 | 芴衍生物的结晶多形体及其制造方法 |
| CN104230671A (zh) * | 2014-07-18 | 2014-12-24 | 宿迁市永星化工有限公司 | 9,9-双(6-羟基萘-2-基)芴的溶剂合物晶体及其制备 |
| CN107848931A (zh) * | 2015-07-08 | 2018-03-27 | 田冈化学工业株式会社 | 具有芴骨架的醇的晶体及其制造方法 |
| CN106349030A (zh) * | 2015-07-17 | 2017-01-25 | 宿迁市永星化工有限公司 | 高堆积密度9,9-二[3-苯基-4-(2-羟基乙氧基)苯基]芴晶体的制备 |
| JP2017200901A (ja) * | 2015-07-21 | 2017-11-09 | 田岡化学工業株式会社 | フルオレン骨格を有するアルコールの結晶およびその製造方法 |
| JP2018048086A (ja) * | 2016-09-21 | 2018-03-29 | 田岡化学工業株式会社 | フルオレン骨格を有するアルコール化合物の結晶およびその製造方法 |
| JP2018076245A (ja) * | 2016-11-08 | 2018-05-17 | 田岡化学工業株式会社 | フルオレン骨格を有するジヒドロキシ化合物の精製方法 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114890877A (zh) * | 2022-01-28 | 2022-08-12 | 江苏永星化工股份有限公司 | 9,9-二[3-苯基-4-(2-羟基乙氧基)苯基]芴及其制备方法 |
| CN114890877B (zh) * | 2022-01-28 | 2024-03-26 | 江苏永星化工股份有限公司 | 9,9-二[3-苯基-4-(2-羟基乙氧基)苯基]芴及其制备方法 |
Also Published As
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| TW202031630A (zh) | 2020-09-01 |
| WO2020059710A1 (ja) | 2020-03-26 |
| JP7379770B2 (ja) | 2023-11-15 |
| TWI810366B (zh) | 2023-08-01 |
| JPWO2020059710A1 (ja) | 2021-08-30 |
| KR20210063323A (ko) | 2021-06-01 |
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