CN112516027A - Fermented skin care composition - Google Patents
Fermented skin care composition Download PDFInfo
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- CN112516027A CN112516027A CN202011476385.0A CN202011476385A CN112516027A CN 112516027 A CN112516027 A CN 112516027A CN 202011476385 A CN202011476385 A CN 202011476385A CN 112516027 A CN112516027 A CN 112516027A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Birds (AREA)
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- Microbiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a fermented skin care composition which comprises the following components in parts by mass: 40.1-0.5 part of decapeptide, 10-15 parts of yeast fermentation lysate filtrate, 12-20 parts of mung bean fermentation liquor, 1-3 parts of glycerol glucoside, 0.1-0.3 part of low molecular sodium hyaluronate, 0.5-2 parts of 1,2 pentanediol and 0.2-0.6 part of 1,2 hexanediol. Compared with the prior art, the invention has the advantages that: the skin care product is rich in fermentation active ingredients, can penetrate dermis to stimulate hyaluronic acid to increase by activating cell regeneration, and improves the water content and water locking degree of skin; on the other hand, the fermentation active substance is composed of small molecules, can enhance the absorption of the skin care product, is quickly absorbed, is mild, and is easier to nourish and improve the skin state.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a fermented skin care composition.
Background
In recent years, with the vigorous development of the Chinese skin care product market, the consumer has increased the consumption capability of top-grade skin care products, so that the knowledge marketing is carried forward, and one principle of high-end skin care products is gradually known by the consumers in China.
The green natural plant resources contain rich biological resources, and the fermentation technology has the functions of enhancing the efficacy of plant raw materials and reducing side effects, so that the effective components are changed into micromolecules which are easier to absorb, and the efficacy of the product is improved.
In skin care, fermentation is to refine small molecular filtrate by fermentation, and if dry or sensitive skin, small molecular skin care products can better permeate, have stronger functions of moistening, repairing and relieving, are more than several times higher than the antioxidant components in wine than grapes, and more importantly, fermentation can improve the density and concentration of skin nutrients such as peptides, proteins, antioxidants and amino acids.
The small molecule filtrate is extracted by fermentation, which is safer than the raw material extracted by physical and chemical methods, and the bad microorganisms can not survive in the fermentation process, so that less preservative is needed to be added, thus the skin care product for use has super efficacy, and the preservative which usually has irritation effect is rarely contained. All of the above results in a more mild, effective and safer formulation.
Disclosure of Invention
The invention aims to provide a fermented skin care composition which is rich in fermented active ingredients, can stimulate hyaluronic acid to increase by activating cell regeneration and penetrating dermis, and improves the moisture content and the water locking degree of skin.
The purpose of the invention is realized by the following technical scheme:
a fermented skin care composition comprises the following components in parts by mass: 40.1-0.5 part of decapeptide, 10-15 parts of yeast fermentation lysate filtrate, 12-20 parts of mung bean fermentation liquor, 1-3 parts of glycerol glucoside, 0.1-0.3 part of low molecular sodium hyaluronate, 0.5-2 parts of 1,2 pentanediol and 0.2-0.6 part of 1,2 hexanediol.
Further, the feed comprises the following components in parts by mass: decapeptide-40.2 parts, yeast fermentation lysate filtrate 12 parts, mung bean fermentation broth 15 parts, glycerol glucoside 1.5 parts, and low-molecular sodium hyaluronate 0.15 parts.
Further, the feed comprises the following components in parts by mass: decapeptide-40.1 parts, yeast fermentation lysate filtrate 10 parts, mung bean fermentation broth 12 parts, glycerol glucoside 1 part, and low-molecular sodium hyaluronate 0.1 part.
Further, the feed comprises the following components in parts by mass: decapeptide-40.5 parts, yeast fermentation lysate filtrate 15 parts, mung bean fermentation broth 20 parts, glycerol glucoside 3 parts, and low-molecular sodium hyaluronate 0.3 parts.
A fermented skin care composition is used as additive for preparing cosmetic, and has an addition amount of 0.1-10%.
Compared with the prior art, the invention has the advantages that:
mung bean fermentation liquor: lactobacillus/semen phaseoli radiati (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation filtrate, water, butylene glycol, glycerol, fructus Citri Grandis (Citrus GRANDIS) seed extract, rhizoma Acori Graminei (Acorus CALAMUS) root extract, and folium Perillae (Perilla octaOIDES) extract.
Decapeptide-4 can penetrate dermis to increase collagen, reverse the aging process of skin through reconstitution from inside to outside, stimulate collagen, elastin and hyaluronic acid to increase, increase the moisture content and hydration of skin, increase skin thickness and reduce fine lines.
The fermented skin care composition provided by the invention is rich in fermented active ingredients, can penetrate dermis to stimulate hyaluronic acid to increase by activating cell regeneration, and improves the moisture content and water locking degree of skin; on the other hand, the fermentation active substance is composed of small molecules, can enhance the absorption of the skin care product, is quickly absorbed, is mild, and is easier to nourish and improve the skin state.
Detailed Description
Example 1
A fermented skin care composition comprises the following components in parts by mass: decapeptide-40.2 parts, yeast fermentation lysate filtrate 12 parts, mung bean fermentation broth 15 parts, glycerol glucoside 1.5 parts, and low-molecular sodium hyaluronate 0.15 parts.
Example 2
A fermented skin care composition comprises the following components in parts by mass: decapeptide-40.1 parts, yeast fermentation lysate filtrate 10 parts, mung bean fermentation broth 12 parts, glycerol glucoside 1 part, and low-molecular sodium hyaluronate 0.1 part.
Example 3
A fermented skin care composition comprises the following components in parts by mass: decapeptide-40.5 parts, yeast fermentation lysate filtrate 15 parts, mung bean fermentation broth 20 parts, glycerol glucoside 3 parts, and low-molecular sodium hyaluronate 0.3 parts.
Example 4
A moisturizing cream comprises the following components: 5% of fermented skin care composition, 4% of butanediol, 3% of glycerol, 1% of betaine, 0.8% of cetyl PEG/PPG-10/1 polydimethylsiloxane, 1.5% of cyclopentadimethylsiloxane, 1% of cyclohexasiloxane, 1% of polydimethylsiloxane, 0.15% of carbomer, 0.15% of triethanolamine and deionized water to 100%.
Example 5
A moisturizing cream comprises the following components: 0.1% of fermented skin care composition, 4% of butanediol, 3% of glycerol, 1% of betaine, 0.8% of cetyl PEG/PPG-10/1 polydimethylsiloxane, 1.5% of cyclopentadimethylsiloxane, 1% of cyclohexasiloxane, 1% of polydimethylsiloxane, 0.15% of carbomer, 0.15% of triethanolamine and deionized water to 100%.
Example 6
A moisturizing cream comprises the following components: 2% of fermented skin care composition, 4% of butanediol, 3% of glycerol, 1% of betaine, 0.8% of cetyl PEG/PPG-10/1 polydimethylsiloxane, 1.5% of cyclopentadimethylsiloxane, 1% of cyclohexasiloxane, 1% of polydimethylsiloxane, 0.15% of carbomer, 0.15% of triethanolamine and deionized water to 100%.
Examples 4-6 the fermented skin care compositions used in the formulations were prepared as in example 1.
And (3) moisturizing efficacy verification:
skin surface moisture loss (TEWL) measurements:
30 dry skin volunteers and 20 different skin types of each experimental group were selected for use in winter, the age was 22-55 years, and all subjects were dry skin with dry skin and fine wrinkles. The amount of water lost from the skin of 30 subjects was measured before application of the moisturizing cream prepared in examples 4 to 6 and after application for 1 hour, 2 hours and 4 hours.
And (3) testing environment: the room temperature is 25 +/-1 ℃, and the humidity is 47 +/-7%.
The instrument comprises the following steps: finland Delfin Vapometer percutaneous water loss measuring instrument
The smaller the value of the TEWL mean value of the percutaneous water loss is, the less the water loss is, the stronger the water locking capacity is, and the better the moisturizing effect is; conversely, the weaker the water-holding capacity. The results are shown in Table 1.
Table 1: water dispersion loss measured at different times
0h | 1h | 2h | 4h | |
Example 4 | 13.8 | 13.3 | 12.6 | 11.3 |
Example 5 | 13.6 | 13.1 | 10.7 | 9.8 |
Example 6 | 13.3 | 12.9 | 11.3 | 10.1 |
As can be seen from table 1, the water dispersion loss is significantly reduced after the moisturizing creams prepared in examples 4 to 6 are used, and thus, the fermented skin care composition provided by the invention can be used as an additive for preparing skin care products, and can reduce the water loss of skin, lock water and moisturize skin.
Moisture content of the surface layer:
the instrument comprises the following steps: medical epidermis water content measuring instrument of Moisturemeter Epi D
30 subjects were selected for each group, and the moisture content of the facial skin was measured before application, 5min after application, 1h after application, 2h after application, and 4h at 22 ℃. + -. 1 ℃ and a humidity of 50%. + -. 5%. The data are measured 3 times before and after the same tested part, and the average value is taken for comparative evaluation.
Table 2: moisture content of surface layer of each experimental group
As can be seen from Table 2, examples 4-6 showed a significant increase in skin moisture content after application of moisturizing creams prepared from the fermented skin care compositions provided by the present invention. From examples 1-6, it can be seen that the components of the fermented skin care composition of the present invention synergistically act, and can be rapidly absorbed by the skin, retain the moisture of the skin, continuously moisturize and moisturize, and exhibit excellent moisturizing effects.
Claims (5)
1. The fermented skin care composition is characterized by comprising the following components in parts by mass: 40.1-0.5 part of decapeptide, 10-15 parts of yeast fermentation lysate filtrate, 12-20 parts of mung bean fermentation liquor, 1-3 parts of glycerol glucoside, 0.1-0.3 part of low molecular sodium hyaluronate, 0.5-2 parts of 1,2 pentanediol and 0.2-0.6 part of 1,2 hexanediol.
2. The fermented skin care composition according to claim 1, comprising the following components in parts by mass: decapeptide-40.2 parts, yeast fermentation lysate filtrate 12 parts, mung bean fermentation broth 15 parts, glycerol glucoside 1.5 parts, and low-molecular sodium hyaluronate 0.15 parts.
3. The fermented skin care composition according to claim 1, comprising the following components in parts by mass: decapeptide-40.1 parts, yeast fermentation lysate filtrate 10 parts, mung bean fermentation broth 12 parts, glycerol glucoside 1 part, and low-molecular sodium hyaluronate 0.1 part.
4. The fermented skin care composition according to claim 1, comprising the following components in parts by mass: decapeptide-40.5 parts, yeast fermentation lysate filtrate 15 parts, mung bean fermentation broth 20 parts, glycerol glucoside 3 parts, and low-molecular sodium hyaluronate 0.3 parts.
5. Use of a fermented skin care composition according to any of claims 1 to 4 as an additive in the preparation of a cosmetic product in an amount of 0.1 to 10%.
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CN202011476385.0A CN112516027A (en) | 2020-12-15 | 2020-12-15 | Fermented skin care composition |
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CN202011476385.0A CN112516027A (en) | 2020-12-15 | 2020-12-15 | Fermented skin care composition |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107519089A (en) * | 2017-09-07 | 2017-12-29 | 蝶柔化妆品(浙江)有限公司 | A kind of honeycomb hyaluronic acid stoste |
CN109498487A (en) * | 2018-11-27 | 2019-03-22 | 广州伽德中医药科技有限公司 | Cosmetic composition and its preparation method and application is repaired in a kind of moisturizing |
CN110772433A (en) * | 2019-11-15 | 2020-02-11 | 杭州百芮生物科技有限公司 | Composite multiple anagen activation essence and preparation method thereof |
CN111407700A (en) * | 2020-04-22 | 2020-07-14 | 广州市拉凯尔干细胞研究所 | Skin collagen growth promoter and preparation method thereof |
CN112043619A (en) * | 2020-08-20 | 2020-12-08 | 广州优理氏生物科技有限公司 | Peptide composition with repairing effect and preparation method and application thereof |
-
2020
- 2020-12-15 CN CN202011476385.0A patent/CN112516027A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107519089A (en) * | 2017-09-07 | 2017-12-29 | 蝶柔化妆品(浙江)有限公司 | A kind of honeycomb hyaluronic acid stoste |
CN109498487A (en) * | 2018-11-27 | 2019-03-22 | 广州伽德中医药科技有限公司 | Cosmetic composition and its preparation method and application is repaired in a kind of moisturizing |
CN110772433A (en) * | 2019-11-15 | 2020-02-11 | 杭州百芮生物科技有限公司 | Composite multiple anagen activation essence and preparation method thereof |
CN111407700A (en) * | 2020-04-22 | 2020-07-14 | 广州市拉凯尔干细胞研究所 | Skin collagen growth promoter and preparation method thereof |
CN112043619A (en) * | 2020-08-20 | 2020-12-08 | 广州优理氏生物科技有限公司 | Peptide composition with repairing effect and preparation method and application thereof |
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