CN112512531B - 用于膀胱癌的治疗的方法 - Google Patents

用于膀胱癌的治疗的方法 Download PDF

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Publication number
CN112512531B
CN112512531B CN201980050644.2A CN201980050644A CN112512531B CN 112512531 B CN112512531 B CN 112512531B CN 201980050644 A CN201980050644 A CN 201980050644A CN 112512531 B CN112512531 B CN 112512531B
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China
Prior art keywords
compound
sting
vol
mixture
bladder cancer
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Chinese (zh)
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CN112512531A (zh
Inventor
金大式
方家范
远藤笃史
崔亨旭
郝鸣鸿
鲍幸峰
黄冠群
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Sanitary Material R&d Management Co ltd
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Sanitary Material R&d Management Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201980050644.2A 2018-06-01 2019-05-31 用于膀胱癌的治疗的方法 Active CN112512531B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862679495P 2018-06-01 2018-06-01
US62/679,495 2018-06-01
US201962826347P 2019-03-29 2019-03-29
US62/826,347 2019-03-29
PCT/US2019/034933 WO2019232392A1 (en) 2018-06-01 2019-05-31 Methods for the treatment of bladder cancer

Publications (2)

Publication Number Publication Date
CN112512531A CN112512531A (zh) 2021-03-16
CN112512531B true CN112512531B (zh) 2024-04-09

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ID=67138025

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CN201980050644.2A Active CN112512531B (zh) 2018-06-01 2019-05-31 用于膀胱癌的治疗的方法

Country Status (11)

Country Link
US (1) US12251394B2 (https=)
EP (1) EP3801561B1 (https=)
JP (1) JP7335277B2 (https=)
KR (1) KR20210015937A (https=)
CN (1) CN112512531B (https=)
AU (1) AU2019277679B2 (https=)
BR (1) BR112020024605A2 (https=)
CA (1) CA3101623A1 (https=)
MX (1) MX2020012964A (https=)
SG (1) SG11202011434SA (https=)
WO (1) WO2019232392A1 (https=)

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Publication number Priority date Publication date Assignee Title
TW202200136A (zh) 2020-04-10 2022-01-01 日商小野藥品工業股份有限公司 癌治療方法
JP2024533394A (ja) 2021-09-09 2024-09-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 Stingアゴニストのバイオマーカー及びその使用方法

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WO2017027645A1 (en) * 2015-08-13 2017-02-16 Merck Sharp & Dohme Corp. Cyclic di-nucleotide compounds as sting agonists
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JOP20170188A1 (ar) 2016-11-25 2019-01-30 Janssen Biotech Inc ثنائي النوكليوتيدات الحلقية كمنبهات ستينغ (sting)
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Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2016120305A1 (en) * 2015-01-29 2016-08-04 Glaxosmithkline Intellectual Property Development Limited Cyclic dinucleotides useful for the treatment of inter alia cancer
WO2017027645A1 (en) * 2015-08-13 2017-02-16 Merck Sharp & Dohme Corp. Cyclic di-nucleotide compounds as sting agonists
WO2018152450A1 (en) * 2017-02-17 2018-08-23 Eisai R&D Management Co., Ltd. Cyclic di-nucleotides compounds for the treatment of cancer

Also Published As

Publication number Publication date
WO2019232392A1 (en) 2019-12-05
JP7335277B2 (ja) 2023-08-29
CN112512531A (zh) 2021-03-16
US12251394B2 (en) 2025-03-18
CA3101623A1 (en) 2019-12-05
US20210205348A1 (en) 2021-07-08
MX2020012964A (es) 2021-02-16
AU2019277679B2 (en) 2024-11-28
SG11202011434SA (en) 2020-12-30
EP3801561A1 (en) 2021-04-14
JP2021525758A (ja) 2021-09-27
BR112020024605A2 (pt) 2021-04-06
KR20210015937A (ko) 2021-02-10
EP3801561B1 (en) 2025-03-19
AU2019277679A1 (en) 2020-12-24

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