CN112512517A - 作为免疫增强剂的尿石素a - Google Patents
作为免疫增强剂的尿石素a Download PDFInfo
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- CN112512517A CN112512517A CN201980044615.5A CN201980044615A CN112512517A CN 112512517 A CN112512517 A CN 112512517A CN 201980044615 A CN201980044615 A CN 201980044615A CN 112512517 A CN112512517 A CN 112512517A
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- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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| GBGB1807051.6A GB201807051D0 (en) | 2018-04-30 | 2018-04-30 | Biological enhancer |
| GBGB1807819.6A GB201807819D0 (en) | 2018-05-14 | 2018-05-14 | Biological enhancer |
| GB1807819.6 | 2018-05-14 | ||
| PCT/EP2019/061093 WO2019211294A1 (en) | 2018-04-30 | 2019-04-30 | Urolithin a as immune enhancer |
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| EP (1) | EP3787615A1 (https=) |
| JP (2) | JP7557374B2 (https=) |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113813255A (zh) * | 2021-10-20 | 2021-12-21 | 山东大学 | 尿石素a及其衍生物在肿瘤免疫治疗的应用 |
| CN117180267A (zh) * | 2023-10-25 | 2023-12-08 | 深圳市第三人民医院(深圳市肝病研究所) | 一种尿石素a在制备药物中的应用及药物 |
| WO2025224366A1 (en) * | 2024-04-26 | 2025-10-30 | Amazentis Sa | Immune health improvers |
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| CA3291904A1 (en) | 2012-06-27 | 2026-03-02 | Amazentis Sa | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
| JP7557374B2 (ja) | 2018-04-30 | 2024-09-27 | アマゼンティス エスアー | 免疫増強剤としてのウロリチンａ |
| JP7677893B2 (ja) * | 2019-01-18 | 2025-05-15 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 幹細胞機能を向上させるための薬剤及び方法 |
| GB201912107D0 (en) * | 2019-08-22 | 2019-10-09 | Amazentis Sa | Combination |
| US20240000747A1 (en) * | 2020-11-26 | 2024-01-04 | Daicel Corporation | Sirtuin 6 activator |
| WO2022162471A1 (en) | 2021-01-27 | 2022-08-04 | Vandria Sa | Urolithin derivatives and methods of use thereof |
| AU2022270331A1 (en) * | 2021-05-05 | 2023-10-12 | Ludwig Institute For Cancer Research | Urolithin for increasing stem cell function |
| GB202219317D0 (en) * | 2022-12-20 | 2023-02-01 | Amazentis Sa | Methods for improving mitophagy in subjects |
| GB202308224D0 (en) | 2023-06-01 | 2023-07-19 | Amazentis Sa | Formulation |
Citations (3)
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| CN105142632A (zh) * | 2012-06-27 | 2015-12-09 | 阿马曾提斯公司 | 通过投予尿石素或其前体增强自噬或增加寿命 |
| US20170304263A1 (en) * | 2016-04-20 | 2017-10-26 | John Michael Pezzuto | Antioxidative stress compositions, methods of preparing and uses thereof |
| CN107427488A (zh) * | 2014-12-19 | 2017-12-01 | 光环生命科学有限公司 | 鞣花酸二水合物在食品和保健品中的用途 |
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| US8183282B2 (en) | 2006-04-26 | 2012-05-22 | The Regents Of The University Of California | Therapeutic uses of urolithins |
| US9394269B2 (en) | 2013-12-23 | 2016-07-19 | Amazentis Sa | Process-scale synthesis of urolithins |
| WO2019163176A1 (ja) * | 2018-02-21 | 2019-08-29 | 株式会社ダイセル | ウロリチン類を含有する破骨細胞分化抑制剤 |
| JP7557374B2 (ja) | 2018-04-30 | 2024-09-27 | アマゼンティス エスアー | 免疫増強剤としてのウロリチンａ |
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| CN105142632A (zh) * | 2012-06-27 | 2015-12-09 | 阿马曾提斯公司 | 通过投予尿石素或其前体增强自噬或增加寿命 |
| CN107427488A (zh) * | 2014-12-19 | 2017-12-01 | 光环生命科学有限公司 | 鞣花酸二水合物在食品和保健品中的用途 |
| US20170304263A1 (en) * | 2016-04-20 | 2017-10-26 | John Michael Pezzuto | Antioxidative stress compositions, methods of preparing and uses thereof |
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| FRANCISCO A. TOMA´S-BARBERA´N ET AL.: ""Urolithins, the rescue of "old" metabolites to understand a "new" concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status"", vol. 61, no. 1, pages 1 - 35 * |
| HANLIN ZHANG ET AL.: ""Autophagy andImmune Senescence"", 《TRENDS IN MOLECULAR MEDICINE》, vol. 22, no. 8, pages 1 - 16 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113813255A (zh) * | 2021-10-20 | 2021-12-21 | 山东大学 | 尿石素a及其衍生物在肿瘤免疫治疗的应用 |
| CN113813255B (zh) * | 2021-10-20 | 2023-09-01 | 山东大学 | 尿石素a及其衍生物在肿瘤免疫治疗的应用 |
| CN117180267A (zh) * | 2023-10-25 | 2023-12-08 | 深圳市第三人民医院(深圳市肝病研究所) | 一种尿石素a在制备药物中的应用及药物 |
| CN117180267B (zh) * | 2023-10-25 | 2026-03-13 | 深圳市第三人民医院(深圳市肝病研究所) | 一种尿石素a在制备药物中的应用及药物 |
| WO2025224366A1 (en) * | 2024-04-26 | 2025-10-30 | Amazentis Sa | Immune health improvers |
Also Published As
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| US20230097072A1 (en) | 2023-03-30 |
| EP3787615A1 (en) | 2021-03-10 |
| US11426380B2 (en) | 2022-08-30 |
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| US12109190B2 (en) | 2024-10-08 |
| JP2021522296A (ja) | 2021-08-30 |
| BR112020022159A2 (pt) | 2021-01-26 |
| WO2019211294A1 (en) | 2019-11-07 |
| US10792276B2 (en) | 2020-10-06 |
| US20190328703A1 (en) | 2019-10-31 |
| JP7557374B2 (ja) | 2024-09-27 |
| MX2020011619A (es) | 2021-01-15 |
| JP2024170634A (ja) | 2024-12-10 |
| US20210085642A1 (en) | 2021-03-25 |
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