CN112451411A - Epidermal active collagen stock solution - Google Patents
Epidermal active collagen stock solution Download PDFInfo
- Publication number
- CN112451411A CN112451411A CN202011290109.5A CN202011290109A CN112451411A CN 112451411 A CN112451411 A CN 112451411A CN 202011290109 A CN202011290109 A CN 202011290109A CN 112451411 A CN112451411 A CN 112451411A
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- China
- Prior art keywords
- percent
- collagen
- extract
- epidermal
- emulsifier
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses an epidermal active collagen stock solution, which comprises the following oil phases: 1 to 5 percent of mixed alcohol, 0.2 to 0.8 percent of vaseline, 0.2 to 0.8 percent of hyaluronic acid, 8 to 12 percent of collagen, 1 to 5 percent of olive oil, 0.6 to 1.4 percent of emulsifier and 1 to 5 percent of grease; the composition of the water phase is as follows: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract. The technical scheme of the invention has the beneficial effects that after the collagen is added, the collagen is the main component of human tissues and has inseparable relation with tissues and cells of various organs of a human body, so that the collagen is applied to the repair and regeneration of the tissues of the organs of the human body.
Description
Technical Field
The invention relates to the field of cosmetics, in particular to an epidermal active collagen stock solution.
Background
Collagen, also known as Collagen (Collagen), is the most important component of extracellular matrix, and is a polymer that constitutes various extracellular matrixes, plays a role in binding tissues in animal cells, and is also the most important structural protein of animal structural tissues.
The skin is elastic, mainly because the collagen of the collagen fibers in the dermis layer of the skin forms the scaffold of the skin. As people age, work is busy and tired, the loss of collagen secretion in the skin causes delicate skin to become loose and dry, and problems such as wrinkles and loss of luster occur. Therefore, to maintain youthful skin, the collagen content of the skin must be increased.
Disclosure of Invention
The invention aims to solve the problems and designs an epidermal active collagen stock solution.
The technical scheme of the invention is that the epidermal active collagen stock solution comprises the following components in parts by weight:
the oil phase comprises the following components: 1 to 5 percent of mixed alcohol, 0.2 to 0.8 percent of vaseline, 0.2 to 0.8 percent of hyaluronic acid, 8 to 12 percent of collagen, 1 to 5 percent of olive oil, 0.6 to 1.4 percent of emulsifier and 1 to 5 percent of grease;
the composition of the water phase is as follows: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract.
A method for preparing an epidermal active collagen stock solution comprises the following steps:
s1: weighing 1-5% of mixed alcohol, 0.2-0.8% of vaseline, 0.2-0.8% of hyaluronic acid, 8-12% of collagen, 1-5% of olive oil, 0.6-1.4% of emulsifier and 1-5% of grease according to the proportion, adding the mixture into a mixing tank for mixing and dissolving, and uniformly stirring for later use;
s2: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract are continuously heated to 75 to 80 ℃ under the stirring of 20 to 30 revolutions per minute and sterilized for 20 minutes at constant temperature for standby;
s3: slowly pumping the oil phase into the water phase, scraping the wall and stirring, increasing the rotating speed to 30-60 r/min, stirring for 2-3 min, starting a high-speed homogenizer for processing, and then cooling to obtain a material;
and S4, adding essence, preservative and emulsifier into the oil phase mixture and the water phase mixture, and mixing to obtain the product.
Preferably, the mixing time in the step S1 is 10 to 30 minutes.
Preferably, the heating temperature in the step S1 is 70-90 ℃.
Preferably, in the step S3, the homogenization is performed at a high speed of 3000-5000 rpm for 3-5 minutes, and then the wall scraping speed is reduced to 30-40 rpm.
Preferably, the cooling temperature in the step S3 is 35-40 ℃.
Preferably, the emulsifier includes polysorbate, ceteareth-20, glyceryl stearate, steareth-21 and cetearyl alcohol.
Preferably, the oil or fat comprises coconut oil and caprylic/capric triglyceride.
After the collagen is added into the technical scheme, the collagen is the main component of human tissues and has inseparable relation with various organ tissues and cells of a human body, so the epidermal active collagen stock solution is applied to the repair and regeneration of the organ tissues of the human body. Relevant medical applications of collagen include collagen sponges, silk glands, films (surgical hemostasis, for cardiovascular, neurological, oral, orthopedic, skin, gynecological, etc.) wound dressings, artificial skin, blood vessels, heart valves, eye-cornea protection materials, injectable collagen (for wrinkle removal, soft tissue filling, urinary incontinence treatment, urine reflux, bone tissue regeneration fillers), drug-assisted mechanisms, collagen matrix templates, and the like. Generally, the basic unit of protein is amino acids, while collagen is one of the main components for maintaining compactness and elasticity.
Detailed Description
The present invention will be described in detail below, an epidermal activated collagen stock solution.
Example 1
An epidermal active collagen stock solution comprises the following components in parts by weight:
the oil phase comprises the following components: 1 to 5 percent of mixed alcohol, 0.2 to 0.8 percent of vaseline, 0.2 to 0.8 percent of hyaluronic acid, 8 to 12 percent of collagen, 1 to 5 percent of olive oil, 0.6 to 1.4 percent of emulsifier and 1 to 5 percent of grease;
the composition of the water phase is as follows: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract.
Collagen is the main component of human tissue, and has inseparable relation with various organ tissues and cells of human body, so that it is used for repairing and regenerating human organ tissues. Relevant medical applications of collagen include collagen sponges, silk glands, films (surgical hemostasis, for cardiovascular, neurological, oral, orthopedic, skin, gynecological, etc.) wound dressings, artificial skin, blood vessels, heart valves, eye-cornea protection materials, injectable collagen (for wrinkle removal, soft tissue filling, urinary incontinence treatment, urine reflux, bone tissue regeneration fillers), drug-assisted mechanisms, collagen matrix templates, and the like. Generally, the basic unit of protein is amino acids, while collagen is one of the main components for maintaining compactness and elasticity.
Hyaluronic acid is a transparent acid, originally exists in a gel form in the dermal tissue of human skin, and is responsible for storing water and increasing the skin volume, so that the skin looks plump, plump and elastic;
the olive oil has: the anticancer can reduce cancer occurrence, enhance the treatment effect of chemotherapy and radiotherapy of cancer patients, enhance skin elasticity, and achieve the effects of moistening skin and caring skin.
Example 2
Method for preparing epidermal active collagen stock solution
S1: weighing 1-5% of mixed alcohol, 0.2-0.8% of vaseline, 0.2-0.8% of hyaluronic acid, 8-12% of collagen, 1-5% of olive oil, 0.6-1.4% of emulsifier and 1-5% of grease according to the proportion, adding the mixture into a mixing tank for mixing and dissolving, and uniformly stirring for later use;
s2: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract are continuously heated to 75 to 80 ℃ under the stirring of 20 to 30 revolutions per minute and sterilized for 20 minutes at constant temperature for standby;
s3: slowly pumping the oil phase into the water phase, scraping the wall and stirring, increasing the rotating speed to 30-60 r/min, stirring for 2-3 min, starting a high-speed homogenizer for processing, and then cooling to obtain a material;
and S4, adding essence, preservative and emulsifier into the oil phase mixture and the water phase mixture, and mixing to obtain the product.
Preferably, the mixing time in step S1 is 10 to 30 minutes.
Preferably, the mixing in step S1 is performed at a heating temperature of 70-90 ℃.
Preferably, in step S3, homogenizing is carried out at 3000-.
Preferably, the cooling temperature in the step S3 is 35-40 ℃.
Still further, as a preferred embodiment, the emulsifier includes polysorbate, ceteareth-20, glyceryl stearate, steareth-21 and cetearyl alcohol.
Preferably, the oil or fat further comprises coconut oil and caprylic/capric triglyceride.
The technical solutions described above only represent the preferred technical solutions of the present invention, and some possible modifications to some parts of the technical solutions by those skilled in the art all represent the principles of the present invention, and fall within the protection scope of the present invention.
Claims (8)
1. The epidermal active collagen stock solution is characterized by comprising the following components in parts by weight:
the oil phase comprises the following components: 1 to 5 percent of mixed alcohol, 0.2 to 0.8 percent of vaseline, 0.2 to 0.8 percent of hyaluronic acid, 8 to 12 percent of collagen, 1 to 5 percent of olive oil, 0.6 to 1.4 percent of emulsifier and 1 to 5 percent of grease;
the composition of the water phase is as follows: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract.
2. The method for preparing epidermal active collagen according to claim 1, wherein:
s1: weighing 1-5% of mixed alcohol, 0.2-0.8% of vaseline, 0.2-0.8% of hyaluronic acid, 8-12% of collagen, 1-5% of olive oil, 0.6-1.4% of emulsifier and 1-5% of grease according to the proportion, adding the mixture into a mixing tank for mixing and dissolving, and uniformly stirring for later use;
s2: 1 to 3 percent of sage extract, 0.5 to 2.5 percent of witch hazel extract, 3 to 7 percent of plantain extract and 64.4 to 75.4 percent of purslane extract are continuously heated to 75 to 80 ℃ under the stirring of 20 to 30 revolutions per minute and sterilized for 20 minutes at constant temperature for standby;
s3: slowly pumping the oil phase into the water phase, scraping the wall and stirring, increasing the rotating speed to 30-60 r/min, stirring for 2-3 min, starting a high-speed homogenizer for processing, and then cooling to obtain a material;
and S4, adding essence, preservative and emulsifier into the oil phase mixture and the water phase mixture, and mixing to obtain the product.
3. The method for preparing an epidermal activated collagen solution according to claim 2, wherein the mixing time in step S1 is 10-30 minutes.
4. The method for preparing an epidermal activated collagen solution according to claim 1, wherein the mixing step S1 is performed at a temperature of 70-90 ℃.
5. The method as claimed in claim 1, wherein the homogenizing step S3 is performed at 3000-5000 rpm for 3-5 min, and then the scraping speed is reduced to 30-40 rpm.
6. The method for preparing an epidermal activated collagen solution according to claim 1, wherein the cooling temperature in step S3 is 35-40 ℃.
7. The method for preparing an epidermal active collagen raw solution according to claim 1, wherein the emulsifier comprises polysorbate, ceteareth-20, glyceryl stearate, steareth-21 and cetearyl alcohol.
8. The method of claim 1, wherein the oil comprises coconut oil and caprylic/capric triglyceride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011290109.5A CN112451411A (en) | 2020-11-18 | 2020-11-18 | Epidermal active collagen stock solution |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011290109.5A CN112451411A (en) | 2020-11-18 | 2020-11-18 | Epidermal active collagen stock solution |
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| Publication Number | Publication Date |
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| CN112451411A true CN112451411A (en) | 2021-03-09 |
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| CN202011290109.5A Pending CN112451411A (en) | 2020-11-18 | 2020-11-18 | Epidermal active collagen stock solution |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107189119A (en) * | 2017-07-24 | 2017-09-22 | 苏州景卓生物技术有限公司 | A kind of preparation method and applications of compound sodium hyaluronate collagen hydrogels |
| CN107913218A (en) * | 2017-11-20 | 2018-04-17 | 艾因特丽（苏州）生物科技有限公司 | A kind of compound elite preparation with senile-resistant efficacy and its preparation method and application |
| CN107970166A (en) * | 2017-12-26 | 2018-05-01 | 广州在路上信息科技有限公司 | A kind of beauty skin-care face mask and preparation method thereof |
| CN111329802A (en) * | 2020-03-03 | 2020-06-26 | 澳美制药厂有限公司 | Skin moisturizing lotion and preparation method thereof |
-
2020
- 2020-11-18 CN CN202011290109.5A patent/CN112451411A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107189119A (en) * | 2017-07-24 | 2017-09-22 | 苏州景卓生物技术有限公司 | A kind of preparation method and applications of compound sodium hyaluronate collagen hydrogels |
| CN107913218A (en) * | 2017-11-20 | 2018-04-17 | 艾因特丽（苏州）生物科技有限公司 | A kind of compound elite preparation with senile-resistant efficacy and its preparation method and application |
| CN107970166A (en) * | 2017-12-26 | 2018-05-01 | 广州在路上信息科技有限公司 | A kind of beauty skin-care face mask and preparation method thereof |
| CN111329802A (en) * | 2020-03-03 | 2020-06-26 | 澳美制药厂有限公司 | Skin moisturizing lotion and preparation method thereof |
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Application publication date: 20210309 |