CN108498357A - A kind of human-like collagen facial mask liquid and preparation method thereof - Google Patents
A kind of human-like collagen facial mask liquid and preparation method thereof Download PDFInfo
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- CN108498357A CN108498357A CN201810331726.1A CN201810331726A CN108498357A CN 108498357 A CN108498357 A CN 108498357A CN 201810331726 A CN201810331726 A CN 201810331726A CN 108498357 A CN108498357 A CN 108498357A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The present invention relates to cosmetic technical field, specifically a kind of human-like collagen facial mask liquid and preparation method thereof, the human-like collagen facial mask liquid is prepared by the component of following quality proportionings：Acritamer 940 0.08 0.12%；Hydroxyethyl cellulose 0.09 0.12%；Human-like collagen 1 2%；Collagen wins peptide 0.5 1%；Dipropylene glycol 3.8 4.2%；Propylene glycol 1.8 2.1%；Glycerine 1.8 2.2%；Sodium azulenesulfonate solution 3 5%；GC 04 0.4 0.6%；Triethanolamine 0.09 0.11%；Essence 0.01 0.02%；Deionized water 82.53 87.43%.The human-like collagen facial mask liquid can play better crease-resistant repair, and can reduce injury of the ultraviolet light to skin.
Description
Technical field
The present invention relates to cosmetic technical field, specifically a kind of human-like collagen facial mask liquid and preparation method thereof.
Background technology
Facial mask is the beautiful tool of present many people's indispensabilities, the effect of having tender skin, promote skin vigor, as long as rather
Clock, skin are changed to a new form at once, smooth to compact, it appears that brighter.When skin water shortage is tired out, applies one with facial mask and apply, stand
Radiant effect can be experienced.General facial mask is mainly used for moisturizing, and in daily life, sebaceous glands and sweat gland have once in a while
Block situation so that skin cell activity slows down, thus skin is caused to bear, therefore other than daily skin care, along with fixed
Phase supplements skin moisture using facial mask, activates skin of waking up, the facial mask that can make skin smooth soft and fine but common in a short time is anti-
Reparation aspect of wrinkling and reduction ultraviolet light are to not sufficiently effective in terms of skin damage.
Invention content
In order to overcome the above the deficiencies in the prior art, the task of the present invention is provide a kind of human-like collagen facial mask liquid and
Its production method, the human-like collagen facial mask liquid is other than with water supplement function, moreover it is possible to better crease-resistant repair is played,
And injury of the ultraviolet light to skin can be reduced.
Task human-like collagen facial mask liquid of the present invention is achieved through the following technical solutions：
A kind of human-like collagen facial mask liquid, is prepared by the component of following quality proportionings：
Acritamer 940：0.08-0.12%；
Hydroxyethyl cellulose：0.09-0.12%；
Human-like collagen：1-2%；
Collagen wins peptide：0.5-1%；
Dipropylene glycol：3.8-4.2%；
Propylene glycol：1.8-2.1%；
Glycerine：1.8-2.2%；
Sodium azulenesulfonate solution：3-5%；
GC-04：0.4-0.6%；
Triethanolamine：0.09-0.11%；
Essence：0.01-0.02%；
Deionized water：82.53-87.43%.
Acritamer 940 in the present invention (No. CAS：9007-20-9) the propylene being crosslinked with acrylic acid for pentaerythrite
Sour crosslinked resin is a kind of rheology control agent, has thickening suspension effect.
Hydroxyethyl cellulose in the present invention (No. CAS：It is 9004-62-0) that epoxy second is introduced in methylcellulose (MC)
Alkane substituent group (MS0.3~0.4) is made, and salt tolerance is better than unmodified polymer, the gel temperature of hydroxyethyl cellulose (HEMC)
Degree is also than methylcellulose (MC) height.
Human-like collagen (Human-like Collagen) in the present invention is by biotechnology by human body glue
The mRNA reverse transcriptions of former albumen are at cDNA, and for one section of genetic recombination after digestion in E.coli (Escherichia coli), process is highly dense
Spend a kind of high-molecular biologic albumen of fermentation, separation, renaturation, purifying process production.Collagen is that people's in-vivo content is most
Protein is primarily present in skin, bone, cartilage, tooth, tendon, ligament and the blood vessel of human body, be in connective tissue extremely
Important structural protein plays support organ, protects the function of human body.It can according to the design feature of function and its composition tissue
It is divided into：At fiber collagen, reticulate structure collagen, positioned at the fiber correlation collagen of fiber surface, it is former at beading silk gum, at substrate
Film anchoring fiber collagen has transmembrane structure collagen etc..
Collagen in the present invention wins peptide (INCI：HYDROLYZED COLLAGEN/DIPEPTIDE-1, Chinese name
Claim：Hydrolytic collagen/dipeptides -1), it is a kind of high molecular functional protein, it is the chief component of skin, and it is true to account for skin
The proportion of cortex 80%, it constitutes a fine and closely woven elasticated net, securely locks moisture, support skin, be rich in skin
The collagens characteristic amino acids such as glycine, proline, the hydroxyproline that human body needs, are human body cell especially skin cells
Important component in epimatrix.This composite collagen victory peptide product has the characteristics that：1, increase the water conservation of cuticula
Power enhances the tender degree of skin smooth；2, fine film can be formed on the skin, there is the effect of Firm at once；3, it directly permeates
To dermal layer of the skin, skin fibr tissue mechanism is reformed, promotes cell metabolism, delaying cell aging that fine wrinkles is made to obtain
To releiving；4, the water and oil balance for keeping skin, it is vigorous to avoid the occurrence of fat secretion；5, promote eye circumference to enclose skin microcirculation, reinforce
Eye skin metabolism, improves pouch and livid ring around eye；6, stimulation cell division is proliferated, damaged cell is repaired in differentiation, healing wound
Mouthful；7, injury of the ultraviolet light (UVB) to skin is reduced.
Dipropylene glycol in the present invention (No. CAS：110-98-5) have good moisture, oil and hydrocarbon molten altogether
Ability, and smell is slight, and to skin irritation very little, isomer is evenly distributed unanimously, and quality is splendid.
Propylene glycol in the present invention (No. CAS：Wetting agent 57-55-6) can be used as with glycerine or sorbierite cooperation.
Sodium azulenesulfonate solution in the present invention is prepared by the component of following quality proportionings：Sodium azulenesulfonate 0.45-
0.55% (No. CAS：916445-22-2), axenic purification water 99.45-99.55%.Its effect has：1, natural anti-inflammatory, antiallergy；
2, aqueous easy absorption, sodium gualenate aqueous solution has inflammation caused by controlling a variety of Inflammatory substances, and effect is more lasting, passes through
The direct effect in part inhibits inflammatory cell to release histamine, inhibits the synthesis of prostaglandin E2 in mucous membrane, promotes granulation formation and epithelium
Cell neogenesis；3, ultraviolet light is effectively antagonized, the anti-UV activity indexs of sodium azulenesulfonate solution are higher, and water soluble group is not added
Uvioresistant activity index is relatively low.
GC-04 in the present invention is the mixture being made of hydroxy acetophenone, fatty acid glyceride and decoyl hydroximic acid, is contained
There is natural fatty acid glyceride (No. CAS：542-44-9), decoyl hydroximic acid and parahydroxyacet-ophenone (No. CAS：99-93-4),
Wherein fatty acid glyceride is a kind of active skull cap components being present in human breast milk, can enhance newborn infant diseases resist and
Immunity, the mild polarity of skin is good, inhibits bacterium to agree yeast increment activity, also there is moisturizing, emulsification, moisturizing, wetting and balance
Grease and other effects；Parahydroxyacet-ophenone is present in feverfew artemisia scoparia (Artemisia scoparia Waldst.et kit.)
Stem, leaf and the anti-wormwood artemisia of mattress (A.capillaris Thunb.), Luo Mo sections plant kerr tylophora root (Tylophora Kerrii
It is natural antioxidant in the plants such as root Craib)；Decoyl hydroximic acid is a no added preservative, its energy bactericidal,
Solubilized hydrotropy.
Triethanolamine in the present invention (No. CAS:102-71-6) and Acritamer 940 plays the role of neutralizing thickening.
The invention also discloses a kind of preparation methods of above-mentioned human-like collagen facial mask liquid, include the following steps：
A, weigh Acritamer 940 by quality proportioning, deionized water be made 2% carbomer solution, beaten to thin with homogenizer
It is greasy, material a is made；
B, weigh hydroxyethyl cellulose by quality proportioning, deionized water be made 2% hydroxyethyl cellulose solution, be heated to
Material b is made in transparency liquid；
C, weigh human-like collagen by quality proportioning, collagen victory peptide, deionized water be made 2% hyaluronic acid it is molten
Liquid, hyaluronic acid solution stirring and dissolving to transparent, obtained material c；
D, by material a, b, c and dipropylene glycol, propylene glycol, glycerine, sodium azulenesulfonate solution, GC-04, essence, surplus
Deionized water is dispersed with stirring, and then uses homogenizer homogeneous to no particle, material d is made；
E, triethanolamine is added in material d under stiring, be stirred until homogeneous to get to the human-like collagen facial mask
Liquid.
The effect of the present invention is described further below with reference to attached drawing, to be completely understood by the effect of the present invention.
Description of the drawings
Fig. 1 is the cell quantity variation relation figure for testing skin module in 1；
Fig. 2 is the skin schematic diagram for testing 2 middle-ultraviolet lamp non-irradiated groups；
Fig. 3 is to test in 2 to irradiate the skin schematic diagram of group in ultraviolet light；
Fig. 4 is the skin schematic diagram for testing ultraviolet light irradiation group of the skin after product treatment of the present invention in 2；
Fig. 5 is to test in 3 using the facial local pictures before product of the present invention；
Fig. 6 is that facial local pictures of the product of the present invention after six weeks are used in test 3；
Since the test result picture or photo of test 2 and test 3 are more intuitive, so Fig. 2~4 are picture, Fig. 5~
6 be photo.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that saying that the specific embodiment of description is used only for explaining the present invention herein, it is not used to
Limit the present invention.
Embodiment 1：
A kind of human-like collagen facial mask liquid, is prepared by the component of following quality proportionings：
Acritamer 940：0.08%；
Hydroxyethyl cellulose：0.09%；
Human-like collagen：1%；
Collagen wins peptide：0.5%；
Dipropylene glycol：3.8%；
Propylene glycol：1.8%；
Glycerine：1.8%；
Sodium azulenesulfonate solution：3%；
GC-04：0.4%；
Triethanolamine：0.09%；
Essence：0.01%；
Deionized water：87.43%.
Embodiment 2：
A kind of human-like collagen facial mask liquid, is prepared by the component of following quality proportionings：Acritamer 940：0.12%；
Hydroxyethyl cellulose：0.12%；
Human-like collagen：2%；
Collagen wins peptide：1%；
Dipropylene glycol：4.2%；
Propylene glycol：2.1%；
Glycerine：2.2%；
Sodium azulenesulfonate solution：5%；
GC-04：0.6%；
Triethanolamine：0.11%；
Essence：0.02%；
Deionized water：82.53%.
Embodiment 3：
A kind of human-like collagen facial mask liquid, is prepared by the component of following quality proportionings：
Acritamer 940：0.1%；
Hydroxyethyl cellulose：0.1%；
Human-like collagen：1.5%；
Collagen wins peptide：0.7%；
Dipropylene glycol：4%；
Propylene glycol：2%；
Glycerine：2%；
Sodium azulenesulfonate solution：4%；
GC-04：0.5%；
Triethanolamine：0.1%；
Essence：0.015%；
Deionized water：84.985%.
In a wherein specific embodiment, the preparation method of human-like collagen facial mask liquid includes the following steps：
A, weigh Acritamer 940 by quality proportioning, deionized water be made 2% carbomer solution, beaten to thin with homogenizer
It is greasy, material a is made；
B, weigh hydroxyethyl cellulose by quality proportioning, deionized water be made 2% hydroxyethyl cellulose solution, be heated to
Material b is made in transparency liquid；
C, weigh human-like collagen by quality proportioning, collagen victory peptide, deionized water be made 2% hyaluronic acid it is molten
Liquid, hyaluronic acid solution stirring and dissolving to transparent, obtained material c；
D, by material a, b, c and dipropylene glycol, propylene glycol, glycerine, sodium azulenesulfonate solution, GC-04, essence, surplus
Deionized water is dispersed with stirring, and then uses homogenizer homogeneous to no particle, material d is made；
E, triethanolamine is added in material d under stiring, be stirred until homogeneous to get to the human-like collagen facial mask
Liquid.
Human-like collagen facial mask liquid obtained, facial mask cloth, facial mask bag are packaged into facial mask finished product in bottle placer.
Acritamer 940 in the present invention (No. CAS：9007-20-9) the propylene being crosslinked with acrylic acid for pentaerythrite
Sour crosslinked resin is a kind of rheology control agent, has thickening suspension effect.
Hydroxyethyl cellulose in the present invention (No. CAS：It is 9004-62-0) that epoxy second is introduced in methylcellulose (MC)
Alkane substituent group (MS0.3~0.4) is made, and salt tolerance is better than unmodified polymer, the gel temperature of hydroxyethyl cellulose (HEMC)
Degree is also than methylcellulose (MC) height.
Human-like collagen (Human-like Collagen) in the present invention is by biotechnology by human body glue
The mRNA reverse transcriptions of former albumen are at cDNA, and for one section of genetic recombination after digestion in E.coli (Escherichia coli), process is highly dense
Spend a kind of high-molecular biologic albumen of fermentation, separation, renaturation, purifying process production.Collagen is that people's in-vivo content is most
Protein is primarily present in skin, bone, cartilage, tooth, tendon, ligament and the blood vessel of human body, be in connective tissue extremely
Important structural protein plays support organ, protects the function of human body.It can according to the design feature of function and its composition tissue
It is divided into：At fiber collagen, reticulate structure collagen, positioned at the fiber correlation collagen of fiber surface, it is former at beading silk gum, at substrate
Film anchoring fiber collagen has transmembrane structure collagen etc..
Collagen in the present invention wins peptide, is a kind of high molecular functional protein, it is the main composition portion of skin
Point, the proportion of dermal layer of the skin 80% is accounted for, it constitutes a fine and closely woven elasticated net in skin, securely locks moisture, support
Skin, the collagens characteristic amino acid such as glycine, proline, hydroxyproline needed rich in human body is human body cell spy
It is not important component in skin cell epimatrix.This composite collagen victory peptide product has the characteristics that：1, increase
The moisture holding capacity of cuticula enhances the tender degree of skin smooth；2, fine film can be formed on the skin, there is the effect of Firm at once
Fruit；3, directly penetrate to the skin skin corium, reformation skin fibr tissue mechanism, promotion cell metabolism, delaying cell aging,
Fine wrinkles are made to be releived；4, the water and oil balance for keeping skin, it is vigorous to avoid the occurrence of fat secretion；5, promote eye surrounding skin
Microcirculation reinforces eye skin metabolism, improves pouch and livid ring around eye；6, stimulation cell division is proliferated, differentiation is repaired and is damaged
Cell, healing of wound；7, injury of the ultraviolet light (UVB) to skin is reduced.
Dipropylene glycol in the present invention (No. CAS：110-98-5) have good moisture, oil and hydrocarbon molten altogether
Ability, and smell is slight, and to skin irritation very little, isomer is evenly distributed unanimously, and quality is splendid.
Propylene glycol in the present invention (No. CAS：Wetting agent 57-55-6) can be used as with glycerine or sorbierite cooperation.
Sodium azulenesulfonate solution in the present invention is prepared by the component of following quality proportionings：Sodium azulenesulfonate 0.45-
0.55% (No. CAS：916445-22-2), axenic purification water 99.45-99.55%.Its effect has：1, natural anti-inflammatory, antiallergy；
2, aqueous easy absorption, sodium gualenate aqueous solution has inflammation caused by controlling a variety of Inflammatory substances, and effect is more lasting, passes through
The direct effect in part inhibits inflammatory cell to release histamine, inhibits the synthesis of prostaglandin E2 in mucous membrane, promotes granulation formation and epithelium
Cell neogenesis；3, ultraviolet light is effectively antagonized, the anti-UV activity indexs of sodium azulenesulfonate solution are higher, and water soluble group is not added
Uvioresistant activity index is relatively low.
GC-04 in the present invention contains natural fatty acid glyceride (No. CAS：542-44-9), decoyl hydroximic acid and right
Hydroxy acetophenone (No. CAS：99-93-4), wherein fatty acid glyceride be a kind of natural activity being present in human breast milk at
Point, newborn infant diseases resistance and immunity can be enhanced, the mild polarity of skin is good, inhibits bacterium to agree yeast increment activity, also has
Moisturizing, emulsification, moisturizing, wetting and Sage Extract and other effects；Parahydroxyacet-ophenone is present in feverfew artemisia scoparia
The stem of (Artemisia scoparia Waldst.et kit.), leaf and the anti-wormwood artemisia of mattress (A.capillaris Thunb.), trailing plants
It is natural antioxidant in the plants such as the root of mushroom section plant kerr tylophora root (Tylophora Kerrii Craib)；Decoyl hydroxyl
Oxime acid is a no added preservative, it can bactericidal, solubilized hydrotropy.
Triethanolamine in the present invention (No. CAS:102-71-6) and Acritamer 940 plays the role of neutralizing thickening.
Measure of merit：
Test 1 has excellent activation effect to Skin Cell
Epidermal cell activation experiment：It is artificial skin module in culture dish, comparison smears product of the present invention and do not smear this
Invention product, is tested, and Fig. 1 is the cell quantity variation relation figure of skin module；In Fig. 1, abscissa is time, ordinate
It is cell quantity, series 1 indicates to smear experimental result numerical value line of the product of the present invention after 24 hours, and series 2 indicates not smear
Experimental result numerical value line of the product of the present invention after 24 hours, comparison find that product of the present invention has Skin Cell excellent
Activation effect.
Injury of the ultraviolet light to skin is resisted in test 2
This experiment carries out under the following conditions：
Experiment condition：UVB exposure doses：0.3mW/cm2
Experimental period：Irradiate (every time 2 hours) repeatedly within 6 weeks
Wherein, Fig. 2 is the skin schematic diagram of ultraviolet light non-irradiated group, and Fig. 3 is the skin schematic diagram that group is irradiated in ultraviolet light,
Fig. 4 is the skin schematic diagram that ultraviolet light of the skin after product treatment of the present invention irradiates group；By comparison as can be seen that ultraviolet light
One of injury to skin is exactly that epidermis is excessively formed and (thickens), and product of the present invention can play what inhibition epidermis excessively thickened
Effect, to reduce damage of the ultraviolet light to skin.
Test 3, it is crease-resistant and immediately it is crease-resistant
Subject：Women (55 years old)
Test method：3-4 product of the present invention is used weekly
The experimental result is more intuitive with photo, and Fig. 5 is using the facial local pictures before product of the present invention, and Fig. 6 is to make
With the facial local pictures after product of the present invention six weeks, comparison is found：Product of the present invention can play preferable anti-wrinkle effect.
Above description is only the preferred embodiment of the application and the explanation to institute's application technology principle.People in the art
Member should be appreciated that invention scope involved in the application, however it is not limited to technology made of the specific combination of above-mentioned technical characteristic
Scheme, while should also cover in the case where not departing from the inventive concept, it is carried out by above-mentioned technical characteristic or its equivalent feature
Other technical solutions of arbitrary combination and formation.Such as features described above has similar work(with (but not limited to) disclosed herein
Can technical characteristic replaced mutually and the technical solution that is formed.
Claims (2)
1. a kind of human-like collagen facial mask liquid, which is characterized in that be prepared by the component of following quality proportionings：
Acritamer 940：0.08-0.12%；
Hydroxyethyl cellulose：0.09-0.12%；
Human-like collagen：1-2%；
Collagen wins peptide：0.5-1%；
Dipropylene glycol：3.8-4.2%；
Propylene glycol：1.8-2.1%；
Glycerine：1.8-2.2%；
Sodium azulenesulfonate solution：3-5%；
GC-04：0.4-0.6%；
Triethanolamine：0.09-0.11%；
Essence：0.01-0.02%；
Deionized water：82.53-87.43%；
The GC-04 is the mixture being made of hydroxy acetophenone, fatty acid glyceride and decoyl hydroximic acid.
2. a kind of preparation method based on human-like collagen facial mask liquid described in claim 1, which is characterized in that including following step
Suddenly：
A, weigh Acritamer 940 by quality proportioning, deionized water be made 2% carbomer solution, with homogenizer beat to exquisiteness, system
Obtain material a；
B, weigh hydroxyethyl cellulose by quality proportioning, deionized water be made 2% hydroxyethyl cellulose solution, be heated to transparent
Material b is made in liquid；
C, the hyaluronic acid solution that human-like collagen, collagen victory peptide, deionized water are made 2% is weighed by quality proportioning,
Material c is made to transparent in hyaluronic acid solution stirring and dissolving；
D, by material a, b, c and dipropylene glycol, propylene glycol, glycerine, sodium azulenesulfonate solution, GC-04, essence, surplus go from
Sub- water is dispersed with stirring, and then uses homogenizer homogeneous to no particle, material d is made；
E, triethanolamine is added in material d under stiring, be stirred until homogeneous to get to the human-like collagen facial mask liquid.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810331726.1A CN108498357A (en) | 2018-04-13 | 2018-04-13 | A kind of human-like collagen facial mask liquid and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810331726.1A CN108498357A (en) | 2018-04-13 | 2018-04-13 | A kind of human-like collagen facial mask liquid and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN108498357A true CN108498357A (en) | 2018-09-07 |
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| CN201810331726.1A Pending CN108498357A (en) | 2018-04-13 | 2018-04-13 | A kind of human-like collagen facial mask liquid and preparation method thereof |
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| CN108904399A (en) * | 2018-10-12 | 2018-11-30 | 广州上官靖文化传播有限公司 | It is a kind of to remove acarid, cleaning solution of reparation skin and preparation method thereof |
| CN109172395A (en) * | 2018-09-10 | 2019-01-11 | 广州丽彦妆生物科技有限公司 | Sliding frost of a kind of collagenous shreds and preparation method thereof |
| CN109431854A (en) * | 2018-12-06 | 2019-03-08 | 广州丽彦妆生物科技有限公司 | A kind of bFGF acne hole maintenance freeze-dried powder preparation and preparation method thereof |
| CN111658573A (en) * | 2020-06-17 | 2020-09-15 | 广州艾尔亿医药有限公司 | Human-like serum protein preparation for regenerative medicine cosmetology |
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| CN109172395A (en) * | 2018-09-10 | 2019-01-11 | 广州丽彦妆生物科技有限公司 | Sliding frost of a kind of collagenous shreds and preparation method thereof |
| CN108904399A (en) * | 2018-10-12 | 2018-11-30 | 广州上官靖文化传播有限公司 | It is a kind of to remove acarid, cleaning solution of reparation skin and preparation method thereof |
| CN109431854A (en) * | 2018-12-06 | 2019-03-08 | 广州丽彦妆生物科技有限公司 | A kind of bFGF acne hole maintenance freeze-dried powder preparation and preparation method thereof |
| CN111658573A (en) * | 2020-06-17 | 2020-09-15 | 广州艾尔亿医药有限公司 | Human-like serum protein preparation for regenerative medicine cosmetology |
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