CN107049894A - A kind of daily repairing type Essence and preparation method thereof - Google Patents

A kind of daily repairing type Essence and preparation method thereof Download PDF

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Publication number
CN107049894A
CN107049894A CN201710221616.5A CN201710221616A CN107049894A CN 107049894 A CN107049894 A CN 107049894A CN 201710221616 A CN201710221616 A CN 201710221616A CN 107049894 A CN107049894 A CN 107049894A
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China
Prior art keywords
parts
oligopeptides
repairing type
type essence
collagen
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Pending
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CN201710221616.5A
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Chinese (zh)
Inventor
李忠泽
李巧玲
王平
王铁群
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Guangdong Baby Technology Co Ltd
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Guangdong Baby Technology Co Ltd
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Priority to CN201710221616.5A priority Critical patent/CN107049894A/en
Publication of CN107049894A publication Critical patent/CN107049894A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of daily repairing type Essence, including following component in parts by weight：26 parts of human-like collagen, 38 parts of oligopeptides, 0.1 0.2 parts of aloe powder, 0.1 0.2 parts of hyaluronic acid, 3 10 parts of glycerine, 0.5 1.5 parts of propane diols, 15 parts of 1,3 butanediol, 0.2 0.4 parts of Phenoxyethanol, 0.05 0.08 parts of Sensiva SC50,75 90 parts of water.The present invention proposes a kind of daily repairing type Essence, and the main function composition of Essence includes human-like collagen, oligopeptides and aloe powder, and human collagen and oligopeptides can accelerate histocyte reparation, increase skin elasticity, replenishing water and preserving moisture to keep skin health；Aloe can play a part of anti-inflammation, have certain curative effect to allergic.The each component that Essence proposed by the present invention is used is safe and reliable, and damage will not be caused to skin.

Description

A kind of daily repairing type Essence and preparation method thereof
Technical field
The present invention relates to cosmetic technical field, more particularly to a kind of daily repairing type Essence and preparation method thereof.
Background technology
At present, along with the growth and the increase of life stress at age, skin gradually starts drying, microgroove, black occur The problems such as element precipitation, beauty market also accordingly emerges substantial amounts of facial treatment essence liquid product.But Essence belongs to fine in itself Chemical products, in order to improve beautification function, most materials being harmful to containing lead, mercury, hormone, essence etc. to skin, harmful substance Residual great threat is caused to the health of consumer, therefore people also increasingly pay attention to the composition of skin care item, safety Effective skincare product turns into emphasis of concern.
Chinese patent, applies for notification number：The A of CN 104800128, disclose a kind of multiple-effect without preservative and repair elite Contain the plant extracts such as centella, polygoni cuspidati,radix, scutellaria, tealeaves, glycyrrhiza glabra root in liquid, the Essence, it is safe and With good moisturizing, anti-inflammatory, Shu Min effect.Chinese patent, applies for notification number：The A of CN 106265134, disclose one kind Essence is repaired in polypeptide whitening, and hexapeptide -10, tridecanoic peptide -1 and the carnosine of the Essence are as main functional component, to human body Do not injure, mechanism of action it is clear, skin cell proliferation can be obviously promoted, anti-oxidant, reach the function of repairing skin.
The content of the invention
The technical problem existed based on background technology, the present invention proposes a kind of daily repairing type Essence, the Essence Middle each component is safe, can accelerate histocyte reparation, anti-aging, and also allergic symptom is made moderate progress.
A kind of daily repairing type Essence, including following component in parts by weight：2-6 parts of human-like collagen, widow 3-8 parts of peptide, 0.1-0.2 parts of aloe powder, 0.1-0.2 parts of hyaluronic acid, 3-10 parts of glycerine, 0.5-1.5 parts of propane diols, 1,3- fourths two 1-5 parts of alcohol, 75-90 parts of water.
It is preferred that, the Essence also includes preservative, and the preservative includes 0.2-0.4 parts of Phenoxyethanol, ethyl hexyl 0.05-0.08 parts of base glycerol.
It is preferred that, the human-like collagen is made up of fish scale by saccharomycetes to make fermentation enzymolysis.
It is preferred that, the oligopeptides includes oligopeptides -1, oligopeptides -2 and oligopeptides -5.
It is preferred that, the adding proportion of the oligopeptides -1, oligopeptides -2 and oligopeptides -5 is (5-10)：1：1.
It is preferred that, the mesh number of the aloe powder is 1000-1200 mesh.
A kind of preparation method of daily repairing type Essence, method and step is as follows：S1：By aloe powder, hyaluronic acid, sweet Oil, propane diols, 1,3 butylene glycol, Phenoxyethanol, Sensiva SC50 and water stir at 60 DEG C；S2：Treat made from S1 The temperature of mixed solution is less than 32 DEG C, adds human-like collagen and oligopeptides stirring and dissolving is complete, you can.
A kind of daily repairing type Essence slows down skin aging in preparation, reduces answering in the product that skin lines are produced With.
Human-like collagen (Human-like Collagen) is one obtained by genetic recombination and biotechnology Water soluble polymer biological collagen is planted, it is very much like with human collagen in terms of structure, characteristic.Human-like collagen Can strengthen cell viability, improve microcirculation, supplement collagen and elastin laminin, replenishing water and preserving moisture moisturizing, accelerate histocyte reparation, Loosen smooth out wrinkles, anti-aging makes skin health young.
Oligopeptides refers to that Amino acid profile number is less than 10 peptides, and molecular weight is typically below 1000 dalton, and molecular weight is small Oligopeptides can than polypeptide have higher percutaneous permeability, it is easier to absorbed by human body skin.Oligopeptides can quickly repair impaired Skin, Glycerin, calm down microgroove, enhancing skin elasticity, in addition oligopeptides also have whitening spot-removing function, accelerate melanocyte Metabolism.
Aloe has effects that moisturizing, anti-inflammatory, has good inhibiting effect to a variety of skin pathogenic bacteria；Aloe is to antigen There is strong inhibition with histamine release caused by sensitising chemical, the treatment to acute contact allergy has very much Effect.
Hyaluronic acid can moisten skin smooth in skin surface one layer of ventilative film of formation, and can obstruct external thin Bacterium, dust, the intrusion of ultraviolet, protect the skin from infringement；The best thing of the performance of keeping humidity used for cosmetic that is found in nature Matter.
Sensiva SC50 is a kind of safety broad-spectrum preservative, available in skin care item.
Compared with prior art, the device have the advantages that being：
The present invention proposes a kind of daily repairing type Essence, and the main function composition of Essence includes class people's collagen egg In vain, oligopeptides and aloe powder, human collagen and oligopeptides can accelerate histocyte reparation, increase skin elasticity, replenishing water and preserving moisture to protect Hold skin health；Aloe can play a part of anti-inflammation, have certain curative effect to allergic.Elite proposed by the present invention The each component that liquid is used is safe and reliable, and damage will not be caused to skin.
Embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment 1
A kind of daily repairing type Essence, including following component in parts by weight：2 parts of human-like collagen, oligopeptides 3 Part, 0.1 part of aloe powder, 0.2 part of hyaluronic acid, 10 parts of glycerine, 0.5 part of propane diols, 1 part of 1,3 butylene glycol, Phenoxyethanol 0.2 Part, 0.05 part of Sensiva SC50,75 parts of water.
The adding proportion of oligopeptides -1, oligopeptides -2 and oligopeptides -5 is 5：1：1.
The mesh number of aloe powder is 1000 mesh.
A kind of preparation method of daily repairing type Essence, method and step is as follows：S1：By aloe powder, hyaluronic acid, sweet Oil, propane diols, 1,3 butylene glycol, Phenoxyethanol, Sensiva SC50 and water stir at 60 DEG C；S2：Treat made from S1 The temperature of mixed solution is less than 32 DEG C, adds human-like collagen and oligopeptides stirring and dissolving is complete, you can.
Embodiment 2
A kind of daily repairing type Essence, including following component in parts by weight：6 parts of human-like collagen, oligopeptides 8 Part, 0.2 part of aloe powder, 0.1 part of hyaluronic acid, 3 parts of glycerine, 1.5 parts of propane diols, 5 parts of 1,3 butylene glycol, 0.4 part of Phenoxyethanol, 0.08 part of Sensiva SC50,90 parts of water.
The adding proportion of oligopeptides -1, oligopeptides -2 and oligopeptides -5 is 7：1：1.
The mesh number of aloe powder is 1200 mesh.
Preparation method be the same as Example 1.
Embodiment 3
A kind of daily repairing type Essence, including following component in parts by weight：4 parts of human-like collagen, oligopeptides 5 Part, 0.12 part of aloe powder, 0.12 part of hyaluronic acid, 5 parts of glycerine, 1 part of propane diols, 3 parts of 1,3 butylene glycol, Phenoxyethanol 0.35 Part, 0.06 part of Sensiva SC50,80 parts of water.
The adding proportion of oligopeptides -1, oligopeptides -2 and oligopeptides -5 is 10：1：1.
The mesh number of aloe powder is 1100 mesh.
Preparation method be the same as Example 1.
Embodiment 4
A kind of daily repairing type Essence, including following component in parts by weight：3 parts of human-like collagen, oligopeptides 7 Part, 0.14 part of aloe powder, 0.19 part of hyaluronic acid, 6 parts of glycerine, 0.8 part of propane diols, 4 parts of 1,3 butylene glycol, Phenoxyethanol 0.27 Part, 0.07 part of Sensiva SC50,78 parts of water.
The adding proportion of oligopeptides -1, oligopeptides -2 and oligopeptides -5 is 6：1：1.
The mesh number of aloe powder is 1000 mesh.
Preparation method be the same as Example 1.
Embodiment 5
A kind of daily repairing type Essence, including following component in parts by weight：5 parts of human-like collagen, oligopeptides 6 Part, 0.17 part of aloe powder, 0.11 part of hyaluronic acid, 8 parts of glycerine, 1.2 parts of propane diols, 2 parts of 1,3 butylene glycol, Phenoxyethanol 0.33 Part, 0.05 part of Sensiva SC50,85 parts of water.
The adding proportion of oligopeptides -1, oligopeptides -2 and oligopeptides -5 is 8：1：1.
The mesh number of aloe powder is 1200 mesh.
Preparation method be the same as Example 1.
Experimental test
1st, skin irritation test
Subjects：Choose shaving 3cm at 3-3.5kg healthy rabbits 25, every rabbit back selection 42。
Test method：The Essence implemented obtained by 1-5 is applied to tested material, each embodiment is applied to 5 rabbits；Often 8 hours films once, are observed and record the dermoreaction after 24h and 48 hour.
Result of the test：Found after 24h, 48h observation, 25 tested rabbit do not occur the offices such as rubefaction, dermexanthesis Portion's stimulate the reaction, illustrates that the daily repairing type Essence of the present invention is safe and non-stimulating, without any adverse reaction.
2nd, effect proves experiment
Subjects：30 female volunteers are chosen, the age, volunteer's face had different degrees of take off in 28-55 one full year of life Skin, microgroove or the facial lesion caused by allergy, dark sore etc..
Test method：Face is smeared using the Essence for implementing 3 gained, it is once in the morning and once at night, continuous to use one month.
Examination criteria：(1) it is obviously improved：The impaired skin of face is obviously reduced, and no decortication, skin gloss compacts；(2) it is slight Improve：The impaired skin of face makes moderate progress, and decortication phenomenon mitigates, and the colour of skin has been lifted；(3) without improvement：Use front and rear indifference.
Result of the test：In 30 volunteers, 12 are obviously improved, 18 slight improvement, and 0 without improvement.As a result this is indicated The daily repairing type Essence of invention is directed to the problems such as dry skin, microgroove, skin injury with good effect.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.

Claims (8)

1. a kind of daily repairing type Essence, it is characterised in that including following component in parts by weight：Human-like collagen 2-6 parts, 3-8 parts of oligopeptides, 0.1-0.2 parts of aloe powder, 0.1-0.2 parts of hyaluronic acid, 3-10 parts of glycerine, 0.5-1.5 parts of propane diols, 1-5 parts of 1,3 butylene glycol, 75-90 parts of water.
2. a kind of daily repairing type Essence according to claim 1, it is characterised in that the Essence also includes anti-corrosion Agent, the preservative includes 0.2-0.4 parts of Phenoxyethanol, 0.05-0.08 parts of Sensiva SC50.
3. a kind of daily repairing type Essence according to claim 1, it is characterised in that the human-like collagen be by Fish scale is made by saccharomycetes to make fermentation enzymolysis.
4. a kind of daily repairing type Essence according to claim 1, it is characterised in that the oligopeptides include oligopeptides -1, Oligopeptides -2 and oligopeptides -5.
5. a kind of daily repairing type Essence according to claim 4, it is characterised in that the oligopeptides -1, oligopeptides -2 and The adding proportion of oligopeptides -5 is (5-10)：1：1.
6. a kind of daily repairing type Essence according to claim 1, it is characterised in that the mesh number of the aloe powder is 1000-1200 mesh.
7. a kind of preparation method of daily repairing type Essence according to claim any one of 1-6, it is characterised in that side Method step is as follows：S1：By aloe powder, hyaluronic acid, glycerine, propane diols, 1,3 butylene glycol, Phenoxyethanol, Sensiva SC50 Stirred with water at 60 DEG C；S2：Treat that the temperature of mixed solution made from S1 is less than 32 DEG C, add human-like collagen and widow Peptide stirring and dissolving is complete, you can.
8. a kind of daily repairing type Essence according to claim any one of 1-6 slows down skin aging in preparation, reduce Application in the product that skin lines are produced.
CN201710221616.5A 2017-04-06 2017-04-06 A kind of daily repairing type Essence and preparation method thereof Pending CN107049894A (en)

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107875092A (en) * 2017-11-28 2018-04-06 车碧萍 A kind of after-sun Essence and preparation method thereof
CN108498357A (en) * 2018-04-13 2018-09-07 广州丽彦妆生物科技有限公司 A kind of human-like collagen facial mask liquid and preparation method thereof
CN108785207A (en) * 2018-08-10 2018-11-13 广州碧雅医疗保健科技有限公司 A kind of anti-aging of the ingredient containing Chinese medicine compound prescription is preserved youthful looks skin care compositions and skin care item
CN108836911A (en) * 2018-08-10 2018-11-20 广州碧雅医疗保健科技有限公司 A kind of compact whitening and moistening skin composition and skin care item containing active ingredient of Chinese herbs
CN108852996A (en) * 2018-09-20 2018-11-23 北京原肽干细胞医学研究院有限公司 A kind of skin Essence and preparation method thereof for skin repair
CN109248138A (en) * 2018-10-10 2019-01-22 广州锦同生物科技有限公司 A kind of anti-wrinkle cosmetic composition and preparation method thereof
CN110787117A (en) * 2019-11-15 2020-02-14 杭州倍荣生物科技有限公司 Skin repairing liquid and preparation method thereof
CN110840811A (en) * 2019-11-15 2020-02-28 杭州倍荣生物科技有限公司 Repair essence
CN111195213A (en) * 2018-11-20 2020-05-26 广州市阳光美域日用品有限公司 Preparation method and application of strontium chloride and polypeptide composite preparation
CN111494233A (en) * 2020-06-02 2020-08-07 康珞生物科技（武汉）有限公司 Essence with anti-aging effect
CN111658573A (en) * 2020-06-17 2020-09-15 广州艾尔亿医药有限公司 Human-like serum protein preparation for regenerative medicine cosmetology
CN113057932A (en) * 2021-03-19 2021-07-02 李雪云 Collagen skin care product for improving skin wrinkles

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CN101240313A (en) * 2008-03-07 2008-08-13 陈成 Method for preparing collagen peptide
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CN105662981A (en) * 2016-03-30 2016-06-15 徐鸣 Dual-effect cure essence

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CN101294185A (en) * 2008-06-12 2008-10-29 武汉赛普膜技术有限公司 Method for preparing fish scale collagen peptide with multi-bactery mix fermentation
CN101886106A (en) * 2010-07-02 2010-11-17 湖北远成药业有限公司 Method for extracting collagen peptide from fish scales
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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107875092A (en) * 2017-11-28 2018-04-06 车碧萍 A kind of after-sun Essence and preparation method thereof
CN108498357A (en) * 2018-04-13 2018-09-07 广州丽彦妆生物科技有限公司 A kind of human-like collagen facial mask liquid and preparation method thereof
CN108785207A (en) * 2018-08-10 2018-11-13 广州碧雅医疗保健科技有限公司 A kind of anti-aging of the ingredient containing Chinese medicine compound prescription is preserved youthful looks skin care compositions and skin care item
CN108836911A (en) * 2018-08-10 2018-11-20 广州碧雅医疗保健科技有限公司 A kind of compact whitening and moistening skin composition and skin care item containing active ingredient of Chinese herbs
CN108852996A (en) * 2018-09-20 2018-11-23 北京原肽干细胞医学研究院有限公司 A kind of skin Essence and preparation method thereof for skin repair
CN109248138A (en) * 2018-10-10 2019-01-22 广州锦同生物科技有限公司 A kind of anti-wrinkle cosmetic composition and preparation method thereof
CN111195213A (en) * 2018-11-20 2020-05-26 广州市阳光美域日用品有限公司 Preparation method and application of strontium chloride and polypeptide composite preparation
CN110787117A (en) * 2019-11-15 2020-02-14 杭州倍荣生物科技有限公司 Skin repairing liquid and preparation method thereof
CN110840811A (en) * 2019-11-15 2020-02-28 杭州倍荣生物科技有限公司 Repair essence
CN111494233A (en) * 2020-06-02 2020-08-07 康珞生物科技（武汉）有限公司 Essence with anti-aging effect
CN111494233B (en) * 2020-06-02 2023-07-14 康珞生物科技（武汉）有限公司 Preparation method and application of collagen short peptide liposome
CN111658573A (en) * 2020-06-17 2020-09-15 广州艾尔亿医药有限公司 Human-like serum protein preparation for regenerative medicine cosmetology
CN113057932A (en) * 2021-03-19 2021-07-02 李雪云 Collagen skin care product for improving skin wrinkles

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