CN112120956A - Polypeptide composition for repairing damaged skin - Google Patents

Polypeptide composition for repairing damaged skin Download PDF

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Publication number
CN112120956A
CN112120956A CN202011172884.0A CN202011172884A CN112120956A CN 112120956 A CN112120956 A CN 112120956A CN 202011172884 A CN202011172884 A CN 202011172884A CN 112120956 A CN112120956 A CN 112120956A
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parts
emulsifying pot
stirring
polypeptide composition
skin
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闫泠锟
夏智忆
郭志敏
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Guangzhou Anruoxi Pharmaceutical Technology Co ltd
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Guangzhou Anruoxi Pharmaceutical Technology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The invention discloses a polypeptide composition for repairing damaged skin, which comprises the following components (in percentage by mass): 7-9 parts of fish collagen peptide, 5-7 parts of bioactive peptide, 4-6 parts of ceramide, 4-6 parts of resveratrol, 8-10 parts of antioxidant, 6-8 parts of betaine, 15-17 parts of plant extract, 8-10 parts of glycerol and 35-37 parts of purified water; the polypeptide composition is prepared from fish collagen peptide, bioactive peptide, ceramide, resveratrol, antioxidant, betaine, plant extract, glycerol and purified water by a scientific and reasonable ratio, and can supplement collagen lost in a body in time, accelerate blood circulation, provide nutrition for cells, inhibit the growth of melanin and fade color spots by the synergistic effect of the fish collagen peptide, the bioactive peptide and the ceramide; therefore, the polypeptide composition not only can play a good role in moisturizing skin, but also can repair damaged skin, and simultaneously, the failure speed of skin cells is slowed down, and the skin is kept smooth and moist.

Description

Polypeptide composition for repairing damaged skin
Technical Field
The invention relates to the technical field of repairing damaged skin, in particular to a polypeptide composition for repairing damaged skin.
Background
With the passing of years, the physiological functions of a human body are continuously eliminated, and the signs of skin aging of people are more and more obvious under the influence of adverse factors such as pollution, pressure, ultraviolet rays and the like, such as wrinkles, color spots, skin looseness, chin contour change and the like, and are started and continuously worsened; with the continuous degeneration of physiological functions, the collagen regeneration capacity is greatly reduced, the internal structure of the skin collapses, the skin becomes loose, the lines are abundant, if free radicals cannot be removed, the damaged skin barrier cannot be effectively repaired, the self-renewal repair capacity of the interior of the skin is reduced, and the skin aging speed is accelerated.
In order to promote collagen hyperplasia and reduce wrinkle visibility, the skin repairing cream can help repair skin matrixes and promote self repair and renewal of the skin structures, and rich antioxidant ingredients can help the skin to resist environmental pressure, slow down aging, and be full, compact and permanently moist.
The existing polypeptide composition is biased to moisturizing and moistening, and components for moisturizing and moistening are mainly added into the product, so that the polypeptide composition can play a role in moisturizing and lubricating, but cannot repair damaged skin, and even can cause further damage to the skin, so that the polypeptide composition for repairing the damaged skin is developed.
Disclosure of Invention
The present invention aims to provide a polypeptide composition for repairing damaged skin, which solves the problems of the background art.
In order to achieve the purpose, the invention provides the following technical scheme: a polypeptide composition for repairing damaged skin comprises the following components (in percentage by mass): 7-9 parts of fish collagen peptide, 5-7 parts of bioactive peptide, 4-6 parts of ceramide, 4-6 parts of resveratrol, 8-10 parts of antioxidant, 6-8 parts of betaine, 15-17 parts of plant extract, 8-10 parts of glycerol and 35-37 parts of purified water.
Wherein the bioactive peptide is one or more of lactopeptide, antibacterial peptide and ovalbumin.
Wherein the antioxidant is one or more of glutathione, superoxide dismutase, uric acid and carotene.
Wherein the plant extract is one or more of radix et caulis Opuntiae Dillenii extract, Aloe extract and grape seed extract.
A preparation method of a polypeptide composition for repairing damaged skin comprises the following steps:
s1, weighing purified water and glycerin by an electronic scale according to the weight, adding the weighed purified water and glycerin into an emulsifying pot, stirring for 5-7 minutes by the emulsifying pot, and mixing the glycerin and the purified water;
s2, weighing the fish collagen peptide, the bioactive peptide and the ceramide by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 50-52 ℃, stirring at the speed of 50 r/min, sequentially adding the weighed fish collagen peptide, the bioactive peptide and the ceramide into the emulsifying pot, and stirring for 10-12 minutes by the emulsifying pot;
s3, weighing betaine and plant extracts by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 60-62 ℃, stirring at the speed of 60 r/min, sequentially adding the weighed fish betaine and plant extracts into the emulsifying pot, and stirring for 10-12 min by the emulsifying pot;
s4, weighing resveratrol and an antioxidant by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 80-85 ℃, stirring at the speed of 40 r/min, sequentially adding the weighed resveratrol and the antioxidant into the emulsifying pot, stirring for 30-35 min by the emulsifying pot, adjusting the temperature of the emulsifying pot to the normal temperature state, continuously stirring at the speed of 40 r/min until the temperature of the mixed liquid in the emulsifying pot is reduced to the normal temperature state, discharging, and sterilizing the discharged mixed liquid, thereby obtaining the polypeptide composition for repairing the damaged skin.
Compared with the prior art, the invention has the beneficial effects that:
the polypeptide composition is prepared from fish collagen peptide, bioactive peptide, ceramide, resveratrol, antioxidant, betaine, plant extract, glycerol and purified water by a scientific and reasonable ratio, and can supplement collagen lost in a body in time, accelerate blood circulation, provide nutrition for cells, inhibit the growth of melanin and fade color spots by the synergistic effect of the fish collagen peptide, the bioactive peptide and the ceramide; through the synergistic effect of the betaine and the plant extract, the effects of delaying aging and enhancing immunity can be achieved, and meanwhile, the moisture is supplemented to the skin, so that the effects of moisturizing and moistening the skin are achieved; through the synergistic effect of the resveratrol and the antioxidant, the polypeptide composition can play the role of intracellular antioxidant activity, activate the expression of SIRT1 gene and prevent skin cells from being excessively oxidized, so that the skin cell failure is slowed down, the polypeptide composition not only can play a good moisturizing effect, but also can repair damaged skin, the failure speed of the skin cells is slowed down, and the skin is kept smooth and moist.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Embodiment 1, the present invention provides a technical solution: a polypeptide composition for repairing damaged skin comprises the following components (in percentage by mass): 8 parts of fish collagen peptide, 6 parts of bioactive peptide, 4 parts of ceramide, 4 parts of resveratrol, 8 parts of antioxidant, 6 parts of betaine, 17 parts of plant extract, 10 parts of glycerol and 37 parts of purified water.
The bioactive peptide is a composition of milk peptide, antibacterial peptide and ovalbumin, and the mass ratio of the milk peptide to the antibacterial peptide to the ovalbumin is 1:1: 1.
The antioxidant is a combination of glutathione, superoxide dismutase, uric acid and carotene, and the mass ratio of the glutathione to the superoxide dismutase to the uric acid to the carotene is 1:1:1: 1.
The plant extract is a composition of cactus extract, aloe extract and grape seed extract, and the mass ratio of the cactus extract to the aloe extract to the grape seed extract is 1:1: 1.
Wherein, the fish collagen peptide has the functions of resisting wrinkles and delaying aging, the collagen restores the fractured and aged elastic fiber net to reform the skin tissue structure and stretch wrinkles, and in addition, the fish collagen peptide also clears away free radicals in vivo, resists oxidation and slows down skin aging; the fish collagen peptide has the functions of smoothing fine lines and eliminating red blood streak, and the collagen can rapidly fill collapsed tissues, tighten skin, enhance elasticity, smooth fine lines and prevent and eliminate red blood streak after entering the dermis; the fish collagen peptide has the functions of spot lightening and spot removing, and the collagen can enable cells to be connected more tightly, accelerate the metabolism speed, promote dead skin to fall off, prevent melanin deposition, make skin white and spot lightening; the fish collagen peptide has the effects of whitening and beautifying the skin, and the collagen can inhibit the generation of melanin and prevent the deposition of the melanin, thereby achieving the purpose of whitening.
The bioactive peptide has the effects of promoting skin cell immunity, regulating hormone, resisting bacteria and diseases.
Wherein, ceramide can improve the conditions of dry skin, desquamation, roughness and the like; meanwhile, ceramide can increase the thickness of the horny layer of epidermis, improve the water holding capacity of the skin, reduce wrinkles, enhance the elasticity of the skin and delay the skin aging.
Wherein, the resveratrol has intracellular antioxidant activity and activates the expression of SIRT1 gene, and the NAD + dependent histone deacetylase is contained in the biogenesis of mitochondria and enhances the activities of peroxisome gamma activated proliferator receptor coactivators-1 alpha (PGC-1 alpha) and FOXO, thereby playing a good role in antioxidation.
The antioxidant can play a role in intracellular antioxidant activity and activation of SIRT1 gene expression, and can prevent skin cells from being excessively oxidized, so that skin cell failure is slowed down.
Wherein, the betaine can play a good cleaning role and does not hurt the skin.
The cactus extract has good antioxidation, has remarkable effects of efficiently replenishing water and preventing radiation, ensures high nutrition, high purity and high activity of natural organic functional components, and prevents skin from being ultraviolet.
Wherein, the aloe extract has multiple effects of moisturizing, sun protection, relieving itching, after-sun repair and the like.
The grape seed extract contains a large amount of vitamin e, cellulose and vitamin c, is a strong antioxidant substance, can effectively whiten the skin, can eliminate free radicals in the body and can slow down skin aging.
A preparation method of a polypeptide composition for repairing damaged skin comprises the following steps:
s1, weighing purified water and glycerin by an electronic scale according to the weight, adding the weighed purified water and glycerin into an emulsifying pot, stirring for 5-7 minutes by the emulsifying pot, and mixing the glycerin and the purified water;
s2, weighing the fish collagen peptide, the bioactive peptide and the ceramide by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 50-52 ℃, stirring at the speed of 50 r/min, sequentially adding the weighed fish collagen peptide, the bioactive peptide and the ceramide into the emulsifying pot, and stirring for 10-12 minutes by the emulsifying pot;
s3, weighing betaine and plant extracts by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 60-62 ℃, stirring at the speed of 60 r/min, sequentially adding the weighed fish betaine and plant extracts into the emulsifying pot, and stirring for 10-12 min by the emulsifying pot;
s4, weighing resveratrol and an antioxidant by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 80-85 ℃, stirring at the speed of 40 r/min, sequentially adding the weighed resveratrol and the antioxidant into the emulsifying pot, stirring for 30-35 min by the emulsifying pot, adjusting the temperature of the emulsifying pot to the normal temperature state, continuously stirring at the speed of 40 r/min until the temperature of the mixed liquid in the emulsifying pot is reduced to the normal temperature state, discharging, and sterilizing the discharged mixed liquid, thereby obtaining the polypeptide composition for repairing the damaged skin.
Embodiment 2, the present invention provides a technical solution: a polypeptide composition for repairing damaged skin comprises the following components (in percentage by mass): fish collagen peptide 9, bioactive peptide 7, ceramide 5, resveratrol 5, antioxidant 9, betaine 6, plant extract 15, glycerol 8 and purified water 36.
Wherein the bioactive peptide is a composition of milk peptide and antibacterial peptide, and the mass ratio of the milk peptide to the antibacterial peptide is 1: 1.
Wherein the antioxidant is a combination of glutathione, superoxide dismutase and carotene, and the mass ratio of the glutathione to the superoxide dismutase to the carotene is 1:1: 1.
Wherein the plant extract is a composition of aloe extract and grape seed extract, and the mass ratio of the aloe extract to the grape seed extract is 1: 1.
A preparation method of a polypeptide composition for repairing damaged skin comprises the following steps:
s1, weighing purified water and glycerin by an electronic scale according to the weight, adding the weighed purified water and glycerin into an emulsifying pot, stirring for 5-7 minutes by the emulsifying pot, and mixing the glycerin and the purified water;
s2, weighing the fish collagen peptide, the bioactive peptide and the ceramide by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 50-52 ℃, stirring at the speed of 50 r/min, sequentially adding the weighed fish collagen peptide, the bioactive peptide and the ceramide into the emulsifying pot, and stirring for 10-12 minutes by the emulsifying pot;
s3, weighing betaine and plant extracts by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 60-62 ℃, stirring at the speed of 60 r/min, sequentially adding the weighed fish betaine and plant extracts into the emulsifying pot, and stirring for 10-12 min by the emulsifying pot;
s4, weighing resveratrol and an antioxidant by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 80-85 ℃, stirring at the speed of 40 r/min, sequentially adding the weighed resveratrol and the antioxidant into the emulsifying pot, stirring for 30-35 min by the emulsifying pot, adjusting the temperature of the emulsifying pot to the normal temperature state, continuously stirring at the speed of 40 r/min until the temperature of the mixed liquid in the emulsifying pot is reduced to the normal temperature state, discharging, and sterilizing the discharged mixed liquid, thereby obtaining the polypeptide composition for repairing the damaged skin.
In conclusion, the polypeptide composition is prepared from fish collagen peptide, bioactive peptide, ceramide, resveratrol, antioxidant, betaine, plant extract, glycerol and purified water according to a scientific and reasonable proportion, and the fish collagen peptide, the bioactive peptide and the ceramide have synergistic effect, so that collagen lost in a body can be timely supplemented, blood circulation is accelerated, nutrition is provided for cells, the growth of melanin is inhibited, and color spots are lightened; through the synergistic effect of the betaine and the plant extract, the effects of delaying aging and enhancing immunity can be achieved, and meanwhile, the moisture is supplemented to the skin, so that the effects of moisturizing and moistening the skin are achieved; through the synergistic effect of the resveratrol and the antioxidant, the polypeptide composition can play the role of intracellular antioxidant activity, activate the expression of SIRT1 gene and prevent skin cells from being excessively oxidized, so that the skin cell failure is slowed down, the polypeptide composition not only can play a good moisturizing effect, but also can repair damaged skin, the failure speed of the skin cells is slowed down, and the skin is kept smooth and moist.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1. A polypeptide composition for repairing damaged skin is characterized by comprising the following components (in percentage by mass): 7-9 parts of fish collagen peptide, 5-7 parts of bioactive peptide, 4-6 parts of ceramide, 4-6 parts of resveratrol, 8-10 parts of antioxidant, 6-8 parts of betaine, 15-17 parts of plant extract, 8-10 parts of glycerol and 35-37 parts of purified water.
2. The polypeptide composition for repairing damaged skin according to claim 1, wherein: the bioactive peptide is one or more of lactopeptide, antibacterial peptide and ovalbumin.
3. The polypeptide composition for repairing damaged skin according to claim 2, wherein: the antioxidant is one or more of glutathione, superoxide dismutase, uric acid and carotene.
4. The polypeptide composition for repairing damaged skin according to claim 3, wherein: the plant extract is one or more of cactus extract, aloe extract and grape seed extract.
5. The method for preparing the polypeptide composition for repairing damaged skin according to claims 1 to 4, comprising the following steps:
s1, weighing purified water and glycerin by an electronic scale according to the weight, adding the weighed purified water and glycerin into an emulsifying pot, stirring for 5-7 minutes by the emulsifying pot, and mixing the glycerin and the purified water;
s2, weighing the fish collagen peptide, the bioactive peptide and the ceramide by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 50-52 ℃, stirring at the speed of 50 r/min, sequentially adding the weighed fish collagen peptide, the bioactive peptide and the ceramide into the emulsifying pot, and stirring for 10-12 minutes by the emulsifying pot;
s3, weighing betaine and plant extracts by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 60-62 ℃, stirring at the speed of 60 r/min, sequentially adding the weighed fish betaine and plant extracts into the emulsifying pot, and stirring for 10-12 min by the emulsifying pot;
s4, weighing resveratrol and an antioxidant by an electronic scale according to the weight, adjusting the temperature of an emulsifying pot to 80-85 ℃, stirring at the speed of 40 r/min, sequentially adding the weighed resveratrol and the antioxidant into the emulsifying pot, stirring for 30-35 min by the emulsifying pot, adjusting the temperature of the emulsifying pot to the normal temperature state, continuously stirring at the speed of 40 r/min until the temperature of the mixed liquid in the emulsifying pot is reduced to the normal temperature state, discharging, and sterilizing the discharged mixed liquid, thereby obtaining the polypeptide composition for repairing the damaged skin.
CN202011172884.0A 2020-10-28 2020-10-28 Polypeptide composition for repairing damaged skin Pending CN112120956A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113230183A (en) * 2021-05-13 2021-08-10 广州市万千粉丝化妆品有限公司 Preparation with skin cell repairing active protein peptide and preparation method thereof
CN113633582A (en) * 2021-09-06 2021-11-12 广州安若希医药科技有限公司 Bioactive small-molecule penetration-skin-bottom stock solution and skin care method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004323401A (en) * 2003-04-23 2004-11-18 Mikimoto Pharmaceut Co Ltd Skin care preparation for external use
CN108324676A (en) * 2018-04-28 2018-07-27 广东巴松那生物科技有限公司 A kind of promotion of compacting, anti-aging face cream and preparation method thereof
CN109330964A (en) * 2018-12-14 2019-02-15 广州丽丰化妆品制造有限公司 A kind of anti-ageing anti-wrinkle composition and its preparation method and application
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