CN111265424A - Acne-removing repairing mask liquid, preparation method thereof and acne-removing repairing mask - Google Patents
Acne-removing repairing mask liquid, preparation method thereof and acne-removing repairing mask Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention provides a preparation method of acne-removing repairing facial mask liquid, which comprises the following steps: adding glycine and transdermal absorption enhancer into purified water, and stirring for dissolving to obtain primary solution; weighing hyaluronic acid and tackifier, uniformly spreading on the liquid level of the primary solution, covering a preservative film with the film, and naturally swelling and dissolving to obtain an intermediate solution; and adding the compound fruit and vegetable enzyme and the humectant into the intermediate solution, and uniformly mixing to obtain the acne-removing repairing mask solution. The invention also provides the acne-removing repairing mask liquid obtained by the preparation method of the acne-removing repairing mask liquid. The invention also provides an acne-removing repairing mask, which is prepared by soaking the mask paper in the acne-removing repairing mask liquid. The skin-repairing liquid has the advantages of natural and non-toxic property, good biocompatibility, excellent bacteriostasis, anti-inflammation and skin repairing performance, is easy to be absorbed by skin, is prepared by washing a small amount of residual liquid with clear water, and is suitable for people with various types of skin.
Description
Technical Field
The invention relates to a facial mask liquid, and particularly relates to an acne-removing repairing facial mask liquid.
The invention relates to a preparation method of acne-removing repairing facial mask liquid.
The invention relates to an acne-removing repairing mask.
Background
Acne is a skin disease, also called acne, pimple or face sore, and is a common skin disease caused by puberty development, severe oily skin, preference for spicy and hot stimulation food of fatty and sugar foods or staying up all night. The excessive secretion of sebaceous gland of a patient causes a large amount of cuticle to fall off, and the cuticle is mixed with grease dirt to block pores, so that red swelling and inflammation of hair follicles are caused. In severe cases, the composition also causes hyperpigmentation, leaves pigmentation spots and the like which are difficult to eliminate, and has an influence on the appearance of the patient.
At present, most of cosmetics on the market for treating the pigment deposition caused by whelk act by adding chemical bactericides, hormones and the like, and the components can be sterilized in a short time, but have high skin irritation, and can increase the skin burden of a patient after long-term use. Aiming at a plurality of problems in the existing research, the development of a mask with excellent acne removing and repairing functions is urgently needed.
Disclosure of Invention
The invention aims to solve the technical problem of providing an acne-removing repair facial mask liquid based on natural composite ferment and hyaluronic acid as raw materials.
The invention also aims to solve the technical problem of providing a preparation method of the acne-removing repairing mask liquid.
The invention also aims to solve the technical problem of providing the acne-removing repairing mask.
In order to solve the technical problems, the invention provides a preparation method of an acne-removing repairing mask liquid, which comprises the following steps:
a) taking 1000mL of purified water, adding 0.2% (g/100mL) of glycine and 0.05-0.1% (g/100mL) of transdermal absorption enhancer, and stirring and dissolving to obtain a primary solution;
b) weighing 0.5% (g/100mL) of hyaluronic acid and 0.4% (g/100mL) of tackifier, uniformly scattering on the liquid surface of the primary solution obtained in the step a), covering a preservative film with the film, and naturally swelling and dissolving for 24 hours at 4 ℃ to obtain an intermediate solution;
c) adding 3-5% (mL/100mL) of composite fruit and vegetable enzyme and 6% (mL/100mL) of humectant into the intermediate solution obtained in the step b), and uniformly mixing to obtain the acne-removing repairing mask solution.
Preferably, the composite fruit and vegetable enzyme comprises apple enzyme, grapefruit enzyme, pear enzyme and ginger enzyme, and the volume ratio of the above enzymes is that the apple enzyme: shaddock ferment: pear enzyme: the ratio of the ginger enzyme to the ginger enzyme is 1:1:1: 1.
Preferably, the humectant is glycerin.
Preferably, the tackifier is CMC-Na.
Preferably, the transdermal absorption enhancer is poloxamer 188.
By adopting the method, the effects of removing acne and removing soft horniness of the enzyme are combined with the anti-inflammation effect and the skin repair effect of the hyaluronic acid to achieve the effects of removing acne and repairing, and in order to increase the absorption of the skin to the enzyme and the hyaluronic acid and better exert the effects, the method is added with the transdermal absorption enhancer poloxamer 188. Because the function of the single fermentation enzyme of the fruit is limited, the method adopts a mixed solution of a plurality of fruit (apple, grapefruit and pear) and vegetable (ginger) enzymes, wherein the molecular weight of the sodium hyaluronate is as follows: 3000-5000.
In order to solve the technical problems, the invention also provides the acne-removing repairing mask liquid which is prepared by the preparation method of the acne-removing repairing mask liquid.
The acne-removing repairing facial mask liquid reduces the types of components as much as possible on the premise of meeting the functions of removing acnes and repairing so as to reduce skin irritation and allergy.
In order to solve the technical problems, the invention also provides the acne-removing repairing mask, which is prepared by soaking 20-30 mL of the mask paper in the acne-removing repairing mask liquid for 4-6 hours.
The acne-removing repairing mask prepared by the method is a mask mainly prepared from natural compound enzyme and hyaluronic acid, the acne-removing repairing mask takes the enzyme and the hyaluronic acid as main prescription components, has natural, non-toxic, good biocompatibility, excellent antibacterial, anti-inflammatory and skin repairing performances, is easy to be absorbed by skin, can be prepared by washing a small amount of residual liquid with clear water, and is suitable for people with various types of skin.
Drawings
Fig. 1 is a diagram showing the effect of the third acne-removing repairing mask in the embodiment before and after application.
Detailed Description
Example one
The preparation method of the acne-removing repairing mask liquid comprises the following steps:
a) taking 1000mL of purified water, adding 0.2% (g/100mL) of glycine and 0.05% (g/100mL) of transdermal absorption enhancer, and stirring to dissolve to obtain a primary solution, wherein the transdermal absorption enhancer is poloxamer 188;
b) weighing 0.5% (g/100mL) of hyaluronic acid and 0.4% (g/100mL) of tackifier, uniformly scattering on the liquid surface of the primary solution obtained in the step a), covering a preservative film with the film, and naturally swelling and dissolving for 24 hours at 4 ℃ to obtain an intermediate solution, wherein the tackifier is CMC-Na;
c) adding 3% (mL/100mL) of composite fruit and vegetable enzyme and 6% (mL/100mL) of glycerol into the intermediate solution obtained in the step b), and uniformly mixing to obtain acne-removing repairing facial mask liquid;
compound fruit vegetables ferment includes apple ferment, shaddock ferment, pear ferment, ginger ferment, and the volume ratio of above-mentioned ferment is, the apple ferment: shaddock ferment: pear enzyme: the ratio of the ginger enzyme to the ginger enzyme is 1:1:1: 1.
The acne-removing repairing mask liquid is obtained by adopting the preparation method of the acne-removing repairing mask liquid.
And soaking 20mL of facial mask paper in the acne-removing repairing facial mask solution for 6 hours to obtain the acne-removing repairing facial mask of the embodiment.
Example two
The preparation method of the acne-removing repairing mask liquid comprises the following steps:
a) taking 1000mL of purified water, adding 0.2% (g/100mL) glycine and 0.1% (g/100mL) transdermal absorption enhancer, stirring and dissolving to obtain a primary solution, wherein the transdermal absorption enhancer is poloxamer 188;
b) weighing 0.5% (g/100mL) of hyaluronic acid and 0.4% (g/100mL) of tackifier, uniformly scattering on the liquid surface of the primary solution obtained in the step a), covering a preservative film with the film, and naturally swelling and dissolving for 24 hours at 4 ℃ to obtain an intermediate solution, wherein the tackifier is CMC-Na;
c) adding 5% (mL/100mL) of composite fruit and vegetable enzyme and 6% (mL/100mL) of glycerol into the intermediate solution obtained in the step b), and uniformly mixing to obtain acne-removing repairing facial mask liquid;
compound fruit vegetables ferment includes apple ferment, shaddock ferment, pear ferment, ginger ferment, and the volume ratio of above-mentioned ferment is, the apple ferment: shaddock ferment: pear enzyme: the ratio of the ginger enzyme to the ginger enzyme is 1:1:1: 1.
The acne-removing repairing mask liquid is obtained by adopting the preparation method of the acne-removing repairing mask liquid.
And soaking 30mL of facial mask paper in the acne-removing repairing facial mask liquid for 4 hours to obtain the acne-removing repairing facial mask of the embodiment.
EXAMPLE III
The preparation method of the acne-removing repairing mask liquid comprises the following steps:
a) taking 1000mL of purified water, adding 0.2% (g/100mL) of glycine and 0.08% (g/100mL) of transdermal absorption enhancer, and stirring to dissolve to obtain a primary solution, wherein the transdermal absorption enhancer is poloxamer 188;
b) weighing 0.5% (g/100mL) of hyaluronic acid and 0.4% (g/100mL) of tackifier, uniformly scattering on the liquid surface of the primary solution obtained in the step a), covering a preservative film with the film, and naturally swelling and dissolving for 24 hours at 4 ℃ to obtain an intermediate solution, wherein the tackifier is CMC-Na;
c) adding 4% (mL/100mL) of composite fruit and vegetable enzyme and 6% (mL/100mL) of glycerol into the intermediate solution obtained in the step b), and uniformly mixing to obtain acne-removing repairing facial mask liquid;
compound fruit vegetables ferment includes apple ferment, shaddock ferment, pear ferment, ginger ferment, and the volume ratio of above-mentioned ferment is, the apple ferment: shaddock ferment: pear enzyme: the ratio of the ginger enzyme to the ginger enzyme is 1:1:1: 1.
The acne-removing repairing mask liquid is obtained by adopting the preparation method of the acne-removing repairing mask liquid.
Soaking 25mL of facial mask paper in the acne-removing repairing facial mask solution for 5 hours to obtain the acne-removing repairing facial mask of the embodiment.
The acne-removing repair mask takes enzyme and hyaluronic acid as main prescription components, has natural, non-toxic, good biocompatibility, excellent antibacterial, anti-inflammatory and skin-repairing performances, is easy to be absorbed by skin, is prepared by washing a small amount of residual liquid with clear water, and is suitable for people with various skin types.
Taking the third example as an example, 20 persons are averagely divided into two groups, each group comprises 10 persons, the two groups of experimental groups respectively comprise a control group and a treatment group (10 realizators in the control group are 18-30 years old women, and the treatment group comprises two facial skin sensitive persons, two experimenters with the age over 50 years old, two experimenters with the age less than 18 years old, two male experimenters and two common experimenters); the experimental procedure was as follows:
the experimenters in the control group respectively clean the face with water, dry the face, wait for 5 minutes indoors and test the water content of the facial cells of the experimenters;
the treatment groups respectively clean and dry the face with water, and after the experimenters apply the acne-removing repairing mask on the face for 15 minutes, the experimenters clean and dry the face, wait for 5 minutes indoors, and test the water content of the facial cells of the experimenters, as shown in figure 1.
The water content of the facial cells of the experimenters in the treatment group is averagely improved through measurement, no symptoms such as allergy or inflammation and the like are generated on the faces of the experimenters in the treatment group, and the facial moisturizing effect of the treatment group is improved by 15-20% compared with the effect of pure face washing of the control group.
Hyaluronic acid used in the above three examples was commercially available hyaluronic acid with CAS accession number: 9004-61-9.
The above description is only three embodiments of the present invention, and it should be noted that, for those skilled in the art, several modifications and improvements can be made without departing from the principle of the present invention, and these should also be considered as falling within the protection scope of the present invention.
Claims (7)
1. The preparation method of the acne-removing repairing mask liquid comprises the following steps:
a) taking 1000mL of purified water, adding 0.2% (g/100mL) of glycine and 0.05-0.1% (g/100mL) of transdermal absorption enhancer, and stirring and dissolving to obtain a primary solution;
b) weighing 0.5% (g/100mL) of hyaluronic acid and 0.4% (g/100mL) of tackifier, uniformly scattering on the liquid surface of the primary solution obtained in the step a), covering a preservative film with the film, and naturally swelling and dissolving for 24 hours at 4 ℃ to obtain an intermediate solution;
c) adding 3-5% (mL/100mL) of composite fruit and vegetable enzyme and 6% (mL/100mL) of humectant into the intermediate solution obtained in the step b), and uniformly mixing to obtain the acne-removing repairing mask solution.
2. The preparation method of the acne-removing repairing facial mask liquid according to claim 1, which is characterized by comprising the following steps:
compound fruit vegetables ferment include apple ferment, shaddock ferment, pear ferment, ginger ferment, and the volume ratio of above-mentioned ferment is, the apple ferment: shaddock ferment: pear enzyme: the ratio of the ginger enzyme to the ginger enzyme is 1:1:1: 1.
3. The preparation method of the acne-removing repairing facial mask liquid according to claim 1, which is characterized by comprising the following steps:
the humectant is glycerin.
4. The preparation method of the acne-removing repairing facial mask liquid according to claim 1, which is characterized by comprising the following steps:
the tackifier is CMC-Na.
5. The preparation method of the acne-removing repairing facial mask liquid according to claim 1, which is characterized by comprising the following steps:
the transdermal absorption enhancer is poloxamer 188.
6. The acne-removing and repairing mask liquid is characterized in that: the acne-removing repairing mask liquid obtained by the preparation method of the acne-removing repairing mask liquid according to any one of claims 1 to 5.
7. The acne-removing repairing mask is characterized in that: soaking the facial mask paper in 20-30 mL of the acne-removing repairing facial mask liquid as defined in claim 6 for 4-6 hours to obtain the acne-removing repairing facial mask.
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CN112190508A (en) * | 2020-08-18 | 2021-01-08 | 湖南神农国油生态农业发展有限公司 | Compound acne-removing mask and preparation method thereof |
CN113662905A (en) * | 2021-08-19 | 2021-11-19 | 蓝海细胞(北京)生物科技有限公司 | Preparation method of stem cell exosome facial mask liquid |
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