CN112063635B - 一种rna病毒的靶点序列及其应用 - Google Patents
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Abstract
本发明提供一种RNA病毒的靶点序列，其为RNA病毒基因序列中含20～40个碱基、且与人类基因组序列或相关家畜家禽等物种相似性不低于95％的核酸序列片段；上述RNA病毒的靶点序列选自SEQ ID NO.1～SEQ ID NO.615。本发明还涉及构建上述靶点序列的引物组合物、与上述靶点序列相关的反义RNA等生物材料以及缺失该靶点序列的疫苗设计等相关应用。本发明构建的上述序列的病毒片段具有与人基因组DNA相互作用的功能，且其类似病毒miRNA，同时验证了过表达RNA病毒靶点序列对周围基因表达水平的影响，并提出上述靶点片段是RNA病毒的重要致病物质的全新概念。上述靶点序列对RNA病毒的检测及诊断、药物筛选，进而开展RNA病毒引发的病症的治疗以及设计/优化疫苗方法均具有重要应用价值。
Description
技术领域
本发明涉及生物技术领域，尤其涉及一种RNA病毒的靶点序列及其应用。
背景技术
RNA病毒也称RNA型病毒，是指遗传物质是RNA的病毒。病毒RNA的复制过程中，其错误修复机制的酶的活性很低很低，几乎是没有的，所以其变异很快。而疫苗是要根据病毒的固定核苷酸序列或蛋白进行开发制作的，所以RNA病毒疫苗较难开发。它不可单独进行繁殖，必须在活细胞内才可进行。常见的RNA病毒有：艾滋病病毒、脊髓灰质炎病毒、烟草花叶病毒、SARS病毒、MERS病毒、埃博拉病毒、新型冠状病毒(2019-nCoV)等。冠状病毒是一类带有囊膜的不分节段的正义RNA病毒，能够感染多种哺乳动物和鸟类等宿主，特别是对人类可导致轻度至中度呼吸道疾病。在过去的二十年里，人畜共患传染过程中导致了两种高致病性冠状病毒的出现：严重急性呼吸综合征冠状病毒(severe acute respiratorysyndrome，SARS-CoV)和中东呼吸综合征冠状病毒(Middle East respiratory syndrome，MERS-CoV)。新型冠状病毒肺炎(Corona Virus Disease2019，COVID-19)，简称“新冠肺炎”，是指2019新型冠状病毒感染导致的肺炎。COVID-19是一种急性感染性肺炎，研究人员发现其病原体是由一种先前未在人类中发现的新型β冠状病毒引起的，该病毒随后被世界卫生组织(WHO)命名为severe acute respiratory syndrome-related coronavirus 2(SARS-CoV-2)。新冠肺炎患者初始症状多为发热、乏力和干咳，并逐渐出现呼吸困难等严重表现。部分严重病例可出现急性呼吸窘迫综合征和脓毒症休克，甚至死亡。截至2020年7月7日，SARS-CoV-2在全球188个国家和地区持续蔓延，造成超过1162万确诊病例，53.8万死亡病例。目前没有特异性针对冠状病毒的有效靶点。
核酸是生物体内遗传信息储存与传递的一个重要载体，在生物功能的调控上也发挥着极其重要的作用，随着人们对核酸的结构与功能认识的不断深入，核酸作为药物设计靶点的价值越来越被大家所重视。MicroRNA(miRNA)是一类长约22～25个核苷酸的单链短序列小RNA，它不编码蛋白质，但能以其5’末端第2～8位核苷酸以非完全性碱基配对的方式结合于同源mRNA的3’UTR(3’非转译区)，最初人们认为miRNA的发卡结构中只有其中一条链中的序列发挥调控作用，通过诱导信使RNA(mRNA)的降解和转录后基因沉默来负向调节基因的表达发挥功能，而另一条链会降解掉，但后来越来越多的证据发现miRNA的上下链，都会作为独立的miRNA发挥作用。除了miRNA负向调控，有些个案报道在特殊情况下miRNA能够促进基因的表达或翻译(Vasudevan et al.,2007,Vasudevan and Steitz,2007,Place etal.,2008)。XIAOM等人在2015年发现例如has-miR-26a-1、has-miR-3179和has-24-1等能够与增强子结合，该结果发表在RNABiology杂志上，并在全基因组的水平上激活基因表达(XIAO M,LI J,LI W,et al.2017.MicroRNAs activate gene transcriptionepigenetically as an enhancer trigger.RNA Biol[J],14:1326-1334.)。我们前期工作表明，miRNA的这种特性并非是个例，而是适用于很多组织和细胞。在研究miRNA自身的表观遗传学调控机制时，在7种不同的组织细胞中，对1594条miRNA前体进行了系统分析，意外地发现有300多条miRNA前体在基因组中的位置与增强子的组蛋白修饰标志H3K4mel或H3K27ac高度重叠。这让发明人将同时具有组织细胞特异性的miRNA和增强子这两个重要的分子生物学事件联系起来(Xiao et al.,2017)。基于此，发明人认为miRNA是重要的双功能分子。当miRNA位于细胞浆时，它可以作用于mRNA 3’UTR区域，如同灭火器一样，阻断mRNA的翻译进而发挥基因的负调控作用；与此相反的是，当它位于细胞核中时，就像一个点火器，通过结合增强子改变增强子的染色质状态，从而激活基因的转录表达。发明人把定位于核内并有激活作用的RNA称为NamiRNA(nuclear activating miRNA)。基于此，发明人提出了NamiRNA-增强子-靶基因网络激活模型，用于揭示细胞核内miRNA功能。令人惊喜的是，NamiRNA与靶基因存在直接的正向调控关系，它还参与肿瘤细胞的增殖、迁移与侵袭等生物学行为。
透明质酸(hyaluronic acid，HA)是蛋白多糖中糖胺多糖(glycosaminoglycan，GAG)的主要成分之一，也是目前研究较多的细胞外基质(extracellular matrix，ECM)成分之一，在正常组织功能和发育中发挥重要作用，包括为细胞提供支持和锚定，促进细胞间信号传导以及促进细胞移动和迁移。HA由一类称为HA合成酶(hyaluronic acid synthase，HAS)的整合膜蛋白合成，其中脊椎动物具有三种类型：HAS1、HAS2和HAS3。这些酶通过将葡萄糖醛酸和N-乙酰氨基葡糖反复添加到新生多糖中来延长HA，并通过细胞膜挤出和进入细胞外空间。HA是一种大分子黏性糖胺聚糖，可由Ⅱ型肺上皮细胞、内皮细胞及肺成纤维细胞分泌，其中成纤维细胞可受致病因子，如氧自由基等的刺激合成大量HA。HA的基本结构是β-D葡萄糖酸和2-乙酰基-2-去氧-D-葡萄糖分别以β1.3和β2.4糖苷链连接的重复二糖直链分子聚合体，为最主要的糖胺多糖，HA在肺组织主要分布于毛细血管和细支气管周围的间质中，广泛表达于细胞外基质，也可表达于细胞表面。透明质酸的最大作用就是可以吸收和保存水分，一个透明质酸分子可以吸附9个水分子，透明质酸的增多无疑会加剧局部水分的增多。已有研究表明HA具有增加局部水肿并促进炎症级联反应，导致白细胞迁移、增殖和分化。
透明质酸合成酶抑制剂(4-Methylumbelliferone，4-MU)是HA合成的选择性抑制剂。4-MU是一种香豆素家族的衍生物。其他香豆素衍生物，例如苯丙香豆素
和华法林
由于其抗凝机制多以预防性药物来减少心血管疾病的发生。
ACE2是新型冠状病毒的受体，其表达量与新型冠状病毒引起的疾病的进程有紧密的相关性。
HAS1、HAS2、HAS3是透明质酸合成酶家族，其表达量在细胞外基质中的沉积增加与新型冠状病毒引起的疾病及其并发症有紧密的关系。
FBXO15是F-box蛋白家族的成员，其表达量与炎症应答有紧密的相关性。
MYL9是肌球蛋白轻链9，其表达量与炎症应答有紧密的相关性。
KALRN是RhoGEF激酶，其表达量与结节病的进程和肾脏和肺等多个脏器的炎症有相关性。
ATP8B1是P型阳离子转运ATPase家族的成员，其表达量与炎症应答有紧密的相关性。
IGF2R是胰岛素样生长因子2和甘露糖6-磷酸的受体，其表达量与炎症应答有紧密的相关性。
C5AR1是补体成分5a受体1，其表达量与炎症反应的调控有紧密的相关性。
EPAS1是内皮PAS结构域蛋白1，其表达量与炎症反应的调控有紧密的相关性。
TIMM21是内线粒体膜转位酶21，其表达量与炎症反应的调控有紧密的相关性。
到目前为止，RNA病毒尤其是新型冠状病毒引起非典型肺炎的机制并不清楚，其他相关RNA病毒的致病机制和疫苗设计或生产也存在诸多问题，加之RNA病毒引起的疾病缺乏有效的治疗药物和治疗方案，病毒的毒力及易感人群难以确定，迫切需要研究RNA病毒的致病机制，开发RNA病毒的致病性和人群易感性检测，寻找RNA病毒的特效药物和治疗方案，制备高效低毒的RNA病毒疫苗，为人类战胜RNA病毒感染提出切实可行的中国方案。
发明内容
新冠病毒的RNA序列大约3万个碱基，发明人前期将新冠病毒与人体基因组做比较时，发现新冠病毒核酸序列中隐含了5段人的基因组序列，长度在24-28bp不等。这5段序列在人和灵长类动物中极其保守，序列居然一个碱基也不差，这5段序列的保守性提示其具有重要意义。为了便于对其功能和应用进行研究，发明人随将上述保守序列命名为HIS(HumanInsert Sequence)。与此同时，发明人发现SARS和MERS病毒基因组中也分别有3段和2段人的基因组序列(HIS)。新冠病毒、SARS、MERS毒基因组中HIS的位置分布，主要分布在人体增强子区域，提示其与基因激活有关；SARS-CoV-2中的HIS所在增强子上下游200K范围内含有大量的炎症因子基因；HIS所在的RNA区域可以形成病毒来源的发卡结构，进一步分析发现HIS可以形成发卡结构具有miRNA的前体特征；以HIS为基础通过生物信息学分析和预测其靶基因也大多与炎症因子有关；SARS病毒的和新冠病毒的HIS靶点区域有透明质酸合成酶(HAS)基因；根据发明人前期研究工作中发现并提出的NamiRNA-增强子-基因激活理论(Xiao et al.,2017)，发明人认为新冠病毒及SARS病毒的HIS序列在病毒感染人体后会激活炎症因子，引起炎症因子风暴并可能通过激活透明质酸合成酶产生过量的透明质酸引起肺部毛玻璃样改变进而导致ARDS。鉴于新冠病毒中的HIS序列是冠状病毒致病的重要物质基础和重要发病机制，发明人进一步通过实验证实SARS-COV-2、SARS-COV以及MERS病毒的HIS序列在细胞中过表达时能够激活包括HAS以及炎症因子的表达，同时细胞外的透明质酸产生增加。更加重要的是发现新冠患者血清中的透明质酸含量与患者的病情严重程度密切相关。发明人认为病毒靶点序列也可以引起血液学指标的改变，结合临床数据，可用于临床病情检测。因此，冠状病毒的靶点既可以运用于临床诊断，针对该靶点设计药物治疗以及成为设计/优化疫苗的可能，这一类靶点的开发可以推广至其他RNA病毒，并以典型的冠状病毒、艾滋病病毒、寨卡病毒和埃博拉病毒进行验证，获得相似的结果，尤其其他RNA病毒的HIS序列与人体基因组配对的区域大多与这类RNA病毒的致病性和特征有关联。
与现有技术相比，本发明采用上述技术方案，具有如下技术效果：
本发明通过将RNA病毒的基因序列与人基因组进行对比筛选出多段与人基因组相似性为不低于95％(即互补配对为95％以上)的靶点序列，其结构稳定，且成功构建出的病毒片段具有与人基因组DNA相互作用的功能，且其类似病毒miRNA，同时验证了过表达RNA病毒靶点序列对周围基因表达水平的影响，上述筛选及验证对RNA病毒的诊断及检测、筛选药物进行RNA病毒引发的病症的治疗、以及设计/优化疫苗方面均具有很好的应用价值。
本发明所涉及的RNA病毒包括感染人的RNA病毒，感染家禽家畜以及人畜共患的RNA病毒。其中与人体基因组一致的靶点序列我们命名为HIS(Human Insert Sequence)，与鸡基因组一致的靶点序列命名为CIS(Chicken Insert Sequence)，与猪基因组一致的靶点序列命名为PIS(Pig Insert Sequence)，与狗基因组一致的靶点序列命名为DIS(DogInsert Sequence)，与鸭基因组一致靶点序列命名为MIS(Mallard Insert Sequence)。这些病毒特定的靶点序列可以和SARS-COV-2一样，可以通过增强子激活基因的表达，与病毒在人和其他物种中引起的疾病密切相关，进而做为靶标可用于病毒的毒力判断，其反义RNA序列可用于药物的开发，以及缺失该靶点序列作为减毒疫苗设计的重要策略。
本发明克服现有技术中所存在的缺陷，提供一种RNA病毒的靶点序列，其具有与人类基因组相互作用的功能，并验证了过表达RNA病毒靶点序列对周围基因表达水平的影响，并将该靶点序列及其反义RNA序列进行开发应用于RNA病毒诊断、治疗及其设计/优化疫苗。
为实现上述目的，本发明采用如下技术方案：
本发明的第一个方面是提供一种RNA病毒的靶点序列，所述靶点序列为RNA病毒核苷酸序列中包含的不小于20～40个碱基、且与人类基因组序列的相似性为不低于95％(即95％以上的一致性或互补配对)的核酸序列片段。
为了进一步优化上述RNA病毒的靶点序列，本发明采取的技术措施还包括：
进一步地，所述RNA病毒包括但不限于：新型冠状病毒(severe acuterespiratory syndrome-related coronavirus 2，SARS-CoV-2)、严重急性呼吸综合征冠状病毒(severe acute respiratory syndrome-related coronavirus，SARS-CoV)、中东呼吸综合征冠状病毒(Middle East respiratory syndrome coronavirus，MERS-CoV)、寨卡病毒(zika virus)、埃博拉病毒(ebola virus)、艾滋病病毒、诺如病毒、出血热病毒、肠病毒、克麦罗沃病毒、柯萨奇病毒、甲型肝炎病毒、登革病毒2型、风疹病毒、马尔堡病毒、脊髓灰质炎病毒、呼吸道合胞病毒、腮腺炎病毒、澳大利亚蝙蝠狂犬病毒、汉坦病毒、波瓦生病毒、兰加特病毒、埃亚契病毒、科罗拉多蜱传热病毒、拉沙病毒、鄂木斯克出血热病毒、马丘波病毒、胡宁病毒、瓜纳瑞托病毒、辛诺柏病毒、汉他病毒、普马拉病毒、多布拉伐病毒、汉城病毒、克里米亚-刚果出血热病毒、沙比亚病毒、索戈托病毒、欧洲蝙蝠丽沙病毒1型、欧洲蝙蝠丽沙病毒2型、查帕雷病毒、轮状病毒、泰林埃博拉病毒、本迪布焦埃博拉病毒、立夫特山谷热病毒、伊尔库特病毒、甲型流感病毒、长沼病毒、科萨努尔森林病毒、黑港渠病毒、日本乙型脑炎病毒、杜文哈奇-利萨病毒、Lujo出血热病毒、麻疹病毒、蜱传脑炎病毒、禽流感病毒、猪流感病毒、狂犬病毒等。
进一步地，所述RNA病毒的靶点序列选自SEQ ID NO.1～SEQ ID NO.615中的任一种或几种。进一步地，所述新型冠状病毒的靶点序列包括SEQ ID NO.1～SEQ ID NO.6；和/或，所述严重急性呼吸综合征冠状病毒的靶点序列包括SEQ ID NO.7～SEQ ID NO.9；和/或，所述中东呼吸综合征冠状病毒的靶点序列包括SEQ ID NO.10、SEQ ID NO.11；和/或，所述寨卡病毒的靶点序列包括SEQ ID NO.12～SEQ ID NO.14；和/或，所述埃博拉病毒的靶点序列包括SEQ ID NO.15～SEQ ID NO.17；和/或，所述艾滋病病毒的靶点序列包括SEQ IDNO.18～SEQ ID NO.26；和/或，所述诺如病毒的靶点序列包括SEQ ID NO.27；和/或，所述出血热病毒的靶点序列包括SEQ ID NO.28～SEQ ID NO.30；和/或，所述肠病毒的靶点序列包括SEQ ID NO.31、SEQ ID NO.32；和/或，所述克麦罗沃病毒的靶点序列包括SEQ ID NO.33、SEQ ID NO.34；和/或，所述柯萨奇病毒的靶点序列包括SEQ ID NO.35；和/或，所述甲型肝炎病毒的靶点序列包括SEQ ID NO.36～SEQ ID NO.46；和/或，所述登革病毒2型的靶点序列包括SEQ ID NO.47～SEQ ID NO.50；和/或，所述风疹病毒的靶点序列包括SEQ IDNO.51；和/或，所述马尔堡病毒的靶点序列包括SEQ ID NO.52～SEQ ID NO.56；和/或，所述脊髓灰质炎病毒的靶点序列包括SEQ ID NO.57；和/或，所述呼吸道合胞病毒的靶点序列包括SEQ ID NO.58～SEQ ID NO.85；和/或，所述腮腺炎病毒的靶点序列包括SEQ ID NO.86；和/或，所述澳大利亚蝙蝠狂犬病毒的靶点序列包括SEQ ID NO.87；和/或，所述汉坦病毒的靶点序列包括SEQ ID NO.88～SEQ ID NO.95；和/或，所述波瓦生病毒的靶点序列包括SEQID NO.96、SEQ ID NO.97；和/或，所述兰加特病毒的靶点序列包括SEQ ID NO.98～SEQ IDNO.102；和/或，所述埃亚契病毒的靶点序列包括SEQ ID NO.103～SEQ ID NO.113；和/或，所述科罗拉多蜱传热病毒的靶点序列包括SEQ ID NO.114～SEQ ID NO.134；和/或，所述拉沙病毒的靶点序列包括SEQ ID NO.135、SEQ ID NO.136；和/或，所述鄂木斯克出血热病毒的靶点序列包括SEQ ID NO.137、SEQ ID NO.138；和/或，所述马丘波病毒的靶点序列包括SEQ ID NO.139～SEQ ID NO.140；和/或，所述胡宁病毒的靶点序列包括SEQ ID NO.141；和/或，所述瓜纳瑞托病毒的靶点序列包括SEQ ID NO.142～SEQ ID NO.147；和/或，所述辛诺柏病毒的靶点序列包括SEQ ID NO.148～SEQ ID NO.152；和/或，所述汉他病毒的靶点序列包括SEQ ID NO.153～SEQ ID NO.161；和/或，所述普马拉病毒的靶点序列包括SEQ IDNO.162～SEQ ID NO.173；和/或，所述多布拉伐病毒的靶点序列包括SEQ ID NO.174～SEQID NO.185；和/或，所述汉城病毒的靶点序列包括SEQ ID NO.186～SEQ ID NO.199；和/或，所述克里米亚-刚果出血热病毒的靶点序列包括SEQ ID NO.200～SEQ ID NO.204；和/或，所述沙比亚病毒的靶点序列包括SEQ ID NO.205～SEQ ID NO.212；和/或，所述索戈托病毒的靶点序列包括SEQ ID NO.213～SEQ ID NO.227；和/或，所述欧洲蝙蝠丽沙病毒1型的靶点序列包括SEQ ID NO.228～SEQ ID NO.232；和/或，所述欧洲蝙蝠丽沙病毒2型的靶点序列包括SEQ ID NO.233；和/或，所述查帕雷病毒的靶点序列包括SEQ ID NO.234；和/或，所述轮状病毒的靶点序列包括SEQ ID NO.235～SEQ ID NO.277；和/或，所述泰林埃博拉病毒的靶点序列包括SEQ ID NO.278、SEQ ID NO.279；和/或，所述本迪布焦埃博拉病毒的靶点序列包括SEQ ID NO.280；和/或，所述立夫特山谷热病毒的靶点序列包括SEQ ID NO.281；和/或，所述伊尔库特病毒的靶点序列包括SEQ ID NO.282～SEQ ID NO.285；和/或，所述甲型流感病毒的靶点序列包括SEQ ID NO.286～SEQ ID NO.313；和/或，所述长沼病毒的靶点序列包括SEQ ID NO.314～SEQ ID NO.327；和/或，所述科萨努尔森林病毒的靶点序列包括SEQ ID NO.328；和/或，所述黑港渠病毒的靶点序列包括SEQ ID NO.329～SEQ ID NO.334；和/或，所述日本乙型脑炎病毒的靶点序列包括SEQ ID NO.335～SEQ ID NO.337；和/或，所述杜文哈奇-利萨病毒的靶点序列包括SEQ ID NO.338～SEQ ID NO.344；和/或，所述Lujo出血热病毒的靶点序列包括SEQ ID NO.345；和/或，所述麻疹病毒的靶点序列包括SEQ IDNO.346；和/或，所述蜱传脑炎病毒的靶点序列包括SEQ ID NO.347；和/或，所述禽流感病毒的靶点序列包括SEQ ID NO.348～SEQ ID NO.420；和/或，所述猪流感病毒的靶点序列包括SEQ ID NO.421～SEQ ID NO.521；和/或，所述狂犬病毒的靶点序列包括SEQ ID NO.522～SEQ ID NO.615。
上述靶点序列各片段的命名方式为病毒名加HIS或其他规则名称加片段序号，其靶点序列具体如下表所示：
表1-RNA病毒的靶点序列表
表2-RNA病毒的靶点反义序列表
本发明的第二个目的是提供一种用于构建任一上述的RNA病毒的靶点序列的引物组合物。
进一步地，部分RNA病毒的靶点序列的引物组合物包括以下组中的任一种或几种：靶点序列SEQ ID NO.1的引物为SEQ ID NO.616～SEQ ID NO.619；和/或，靶点序列SEQ IDNO.2的引物为SEQ ID NO.620～SEQ ID NO.623；和/或，靶点序列SEQ ID NO.3的引物为SEQID NO.624～SEQ ID NO.627；和/或，靶点序列SEQ ID NO.4的引物为SEQ ID NO.628～SEQID NO.631和/或，靶点序列SEQ ID NO.5的引物为SEQ ID NO.632～SEQ ID NO.635；和/或，靶点序列SEQ ID NO.7的引物为SEQ ID NO.636～SEQ ID NO.639；和/或，靶点序列SEQ IDNO.8的引物为SEQ ID NO.640～SEQ ID NO.643；和/或，靶点序列SEQ ID NO.10的引物为SEQ ID NO.644～SEQ ID NO.647；和/或，靶点序列SEQ ID NO.11的引物为SEQ ID NO.648～SEQ ID NO.651；和/或，靶点序列SEQ ID NO.12的引物为SEQ ID NO.652～SEQ IDNO.655；和/或，靶点序列SEQ ID NO.13的引物为SEQ ID NO.656～SEQ ID NO.659；和/或，靶点序列SEQ ID NO.14的引物为SEQ ID NO.660～SEQ ID NO.663；和/或，靶点序列SEQ IDNO.15的引物为SEQ ID NO.664～SEQ ID NO.667；和/或，靶点序列SEQ ID NO.16的引物为SEQ ID NO.668～SEQ ID NO.671；和/或，靶点序列SEQ ID NO.17的引物为SEQ ID NO.672～SEQ ID NO.675；和/或，靶点序列SEQ ID NO.18的引物为SEQ ID NO.676～SEQ IDNO.679；和/或，靶点序列SEQ ID NO.19的引物为SEQ ID NO.680～SEQ ID NO.683；和/或，靶点序列SEQ ID NO.20的引物为SEQ ID NO.684～SEQ ID NO.687；和/或，靶点序列SEQ IDNO.21的引物为SEQ ID NO.688～SEQ ID NO.691；和/或，靶点序列SEQ ID NO.22的引物为SEQ ID NO.692～SEQ ID NO.695；和/或，靶点序列SEQ ID NO.23的引物为SEQ ID NO.696～SEQ ID NO.699；和/或，靶点序列SEQ ID NO.24的引物为SEQ ID NO.700～SEQ IDNO.703；和/或，靶点序列SEQ ID NO.25的引物为SEQ ID NO.704～SEQ ID NO.707；和/或，靶点序列SEQ ID NO.26的引物为SEQ ID NO.708～SEQ ID NO.711。
进一步地，在上游引物的5’端前面加上保护碱基和EcoRI酶切位点序列CGGAATTC，下游引物的5’端前面加上保护碱基和BamHI酶切位点序列CGGGATCC。
进一步地，上述引物的具体序列如下表所示：
表3-RNA病毒的靶点序列的扩增引物序列表
本发明的第三个方面是提供针对病毒的RNA药物，其特征在于，所述RNA药物包括，任一上述的RNA病毒靶点序列的反向互补序列、在任一上述的RNA病毒的靶点序列的反向互补序列的3’端进行胆固醇修饰和四个硫代骨架修饰，5’端进行两个硫代骨架修饰，全链进行甲氧基修饰，或，在任一上述的RNA病毒的靶点序列的3’端进行胆固醇修饰和四个硫代骨架修饰，5’端进行两个硫代骨架修饰，全链进行甲氧基修饰。
进一步地，所述.RNA病毒靶点序列的反向互补序列包括反向互补RNA序列或反向互补DNA序列
进一步地，所述RNA药物还包括药学上可接受的载体或赋形剂。
进一步地，所述RNA药物剂型包括形式可为散剂、片剂、颗粒剂、胶囊剂、溶液剂、气雾剂、注射剂、乳剂或混悬剂。
本发明的第四个方面是提供一种与任一上述的RNA病毒的靶点序列相关的生物材料，所述生物材料选自选自下述A)～B)中的一种：
A)与任一上述的RNA病毒的靶点序列互补配对的DNA和/或RNA分子；
B)含有任一上述的的RNA病毒的靶点序列或A)中所述DNA分子的表达盒、重组载体、重组微生物、重组细胞系。
可理解的是，上述DNA分子、表达盒、重组载体、重组微生物、重组细胞系均可为本领域常规使用的生物材料，其均可采用本领域常规方法制备。
进一步地，所述生物材料为重组载体，其构建步骤包括：1)设计引物，PCR扩增所述RNA病毒的靶点序列；2)将扩增的序列片段和表达载体酶切，连接目的序列片段和表达载体；3)将连接产物转化大肠杆菌，培养；4)鉴定后提取重组质粒并包装。其中，RNA病毒的靶点序列如上表1所示，部分引物序列如上表2所示。
进一步地，所述表达载体包括但不限于pCDH载体，其他载体如pCMVp-NEO-BAN载体、pEGFP载体、pEGFT-Actin、pSV2载体、pCDNA载体、pLVX载体、pAAV载体、pET载体、pDsRed载体，其病毒相关重组载体骨架可为本领域使用的任一合适的载体。
进一步地，所述重组载体具有表达病毒相关靶点片段的功能；其中，所述相关靶点片段具有与人类基因组相互作用(相结合)的功能。
进一步地，所述重组载体上有表达新冠病毒SARS-CoV-2、严重急性呼吸综合征冠状病毒SARS-CoV和中东呼吸综合征冠状病毒MERS-CoV的靶点序列，上述靶点序列片段可以与人基因组相互作用(相结合)；具体地，所述靶点序列包括但不限于：SARS-CoV-2-HIS-1、SARS-CoV-2-HIS-2、SARS-CoV-2-HIS-3、SARS-CoV-2-HIS-4、SARS-CoV-2-HIS-5、SARS-CoV-HIS-1、SARS-CoV-HIS-2、MERS-CoV-HIS-1、MERS-CoV-HIS-2。
本发明的第五个方面是提供一种任一上述的RNA病毒的靶点序列的应用，所述应用为在制备RNA病毒检测或诊断试剂中的应用、在制备预防或治疗RNA病毒引发的病症的药物中的应用或者在制备针对RNA病毒的疫苗中的应用。
进一步地，所述病症包括人的疾病、动物的疾病和人畜共患病。
进一步地，所述应用为制备预防或治疗RNA病毒引发的病症的药物中的应用时，通过直接筛选对所述靶点序列进行调控的有效物质；或者，根据所述靶点序列所调控基因的作用，筛选针对所述靶点序列所调控基因及基因产物的有效物质。
进一步地，所述应用为制备针对RNA病毒的疫苗中的应用时，在疫苗设计过程中敲除所述靶点序列。
进一步地，敲除所述靶点序列的方法包括：CRISPR系统和/或核酶技术。
CRISPR来自微生物的免疫系统，这种工程编辑系统利用一种酶，能把一段作为引导工具的小RNA切入DNA，就能在此处切断或做其他改变。以往研究表明，通过这些介入，CRISPR能使基因组更有效地产生变化或突变，效率比TALEN(转录激活因子类感受器核酸酶)等其他基因编辑技术更高。虽然CRISPR有许多优点，在人类癌细胞系列中，它也可能产生大量“误伤目标”，尤其是对不希望改变的基因做修改。
核酶技术属于一种利用核酶的技术，主要是可以进行核酶的设计以进行应用。核酶属于一种能序列特异性剪切RNA的RNA分子，其可以被设计。经过设计的核酶可以用来选择特异性的mRNA片段，也可以通过结合特异性mRNA来阻断其表达。因此，这项技术可以用来进行RNA结构的研究，还可用于异常基因表达导致疾病的治疗。
进一步地，所述疫苗为减毒活疫苗。
本发明的第六个方面是提供了一种减毒活疫苗，所述减毒活疫苗的全基因组不包含上述的RNA病毒的靶点序列。
本发明的第七个方面是提供一种任一上述的RNA病毒的靶点序列在细胞水平上激活相关基因及针对所述相关基因筛选治疗药物中的应用。
进一步地，所述RNA病毒为冠状病毒，具体为新型冠状病毒SARS-CoV-2、严重急性呼吸综合征冠状病毒SARS-CoV、中东呼吸综合征冠状病毒MERS-CoV。
进一步地，在上述应用中，所述相关基因包括ACE2基因、透明质酸合成酶家族HAS1、HAS2、和HAS3的编码基因和/或片段周围200k以内基因。进一步地，所述片段周围200k以内基因包括但不限于FBXO15、MYL9、KALRN、ATP8B1、ZHX2、IGF2R、C5AR1、EPAS1、TIMM21。可理解的是，根据RNA病毒类型的不同，其激活的相关基因也存在区别。
进一步地，所述药物包括miRNA抑制剂。
进一步地，所述miRNA抑制剂包括antagomir抑制剂。
可理解的是，上述药物还可包括其他能抑制被激活靶基因的药物以及其他可调节透明质酸水平(抑制透明质酸合成、降低透明质酸浓度等)的药物。
本发明的第八个方面是提供RNA病毒的靶点序列在研究针对RNA病毒所致疾病的药物靶点中的应用。
进一步，在RNA病毒所致疾病的细胞中找到RNA病毒的靶点序列，并在RNA病毒的靶点序列周围200k以内寻找药物靶点或使用预测软件blast 2.2.30或bedtools 2.29.2在200k以外寻找药物靶点。
本发明的第九个方面是提供一种检测病毒的方法，对上述的RNA病毒的靶点序列进行检测。
进一步，所述靶点序列的检测包括RCR扩增和核苷酸测序。
进一步，这种对RNA病毒的靶点序列进行检测，可用以判断病毒性疾病的诊断，致病性判断及人群易感性检测。
附图说明
图1为本发明一实施例中PCR扩增冠状病毒SARS-CoV-2相关的6个靶点病毒载体的跑胶电泳图。
图2为本发明一实施例中qPCR检测冠状病毒靶点片段在293T细胞内过表达后mRNA水平的结果示意图；其中，***,p<0.001。
图3为本发明一实施例中qPCR检测冠状病毒靶点片段在293T细胞内过表达后基因ACE2的mRNA水平的结果示意图；其中，**,p<0.01,***,p<0.001。
图4为本发明一实施例中qPCR检测冠状病毒靶点片段在293T细胞内过表达后基因HAS1的mRNA水平的结果示意图；其中，**,p<0.01,***,p<0.001。
图5为本发明一实施例中qPCR检测冠状病毒靶点片段在293T细胞内过表达后基因HAS2的mRNA水平的结果示意图；其中，**,p<0.01。
图6为本发明一实施例中qPCR检测冠状病毒靶点片段在293T细胞内过表达后基因HAS3的mRNA水平的结果示意图；其中，**,p<0.01,***,p<0.001。
图7为本发明一实施例中qPCR检测冠状病毒靶点片段SARS-CoV-2-HIS-4在293T细胞内过表达后周围基因FBXO15的mRNA水平的结果示意图；其中，***,p<0.001。
图8为本发明一实施例中qPCR检测冠状病毒靶点片段SARS-CoV-2-HIS-3在293T细胞内过表达后周围基因MYL9的mRNA水平的结果示意图；其中，***,p<0.001。
图9为本发明一实施例中qPCR检测冠状病毒靶点片段SARS-CoV-2-HIS-1在293T细胞内过表达后周围基因ATP8B1的mRNA水平的结果示意图；其中，**,p<0.01。
图10为本发明一实施例中qPCR检测冠状病毒靶点片段SARS-CoV-2-HIS-5在293T细胞内过表达后周围基因KALRN的mRNA水平的结果示意图；其中，**,p<0.01。
图11为本发明一实施例中qPCR检测冠状病毒靶点片段SARS-CoV-2-HIS-6在293T细胞内过表达后周围基因的mRNA水平的结果示意图。
图12为本发明一实施例中qPCR检测冠状病毒靶点片段SARS-CoV-HIS-2在293T细胞内过表达后周围基因的mRNA水平的结果示意图；其中，**,p<0.01.***,p<0.001。
图13为本发明一实施例中qPCR检测冠状病毒靶点片段MERS-CoV-HIS-2在293T细胞内过表达后周围基因的mRNA水平的结果示意图；其中，**,p<0.01。
图14为本发明一实施例中qPCR检测寨卡病毒靶点片段在293T细胞内过表达后周围基因的mRNA水平的结果示意图。
图15为本发明一实施例中qPCR检测埃博拉病毒靶点片段在293T细胞内过表达后周围基因的mRNA水平的结果示意图。
图16为本发明一实施例中qPCR检测艾滋病病毒HIV-2靶点片段在293T细胞内过表达后周围基因的mRNA水平的结果示意图。
图17为本发明一实施例中qPCR检测antagomir对冠状病毒靶点片段SARS-CoV-HIS-2在293T细胞内过表达后周围基因的mRNA水平的结果示意图。
图18为本发明一实施例中qPCR检测antagomir对冠状病毒靶点片段MERS-CoV-HIS-2对激活基因mRNA水平的抑制作用的结果示意图；其中，*<0.05。
图19为本发明一实施例中qPCR检测antagomir对冠状病毒靶点片段SARS-CoV-2-HIS-4对激活基因mRNA水平的抑制作用的结果示意图；其中，*<0.05。
图20为本发明一实施例中qPCR检测antagomir对冠状病毒靶点片段SARS-CoV-2-HIS-3对激活基因mRNA水平的抑制作用的结果示意图；其中，*<0.05。
具体实施方式
下面结合附图和实施例，对本发明的具体实施方式作进一步描述。以下实施例仅用于更加清楚地说明本发明的技术方案，而不能以此来限制本发明的保护范围。下列实施例中未注明具体条件的实验方法，按照本领域常规方法和条件，或按照商品说明书选择；下述实施例中相关试剂及生物材料均为市售产品；下述实施例中的分子克隆技术为现有技术中在分子水平上提供一种纯化和扩增特定DNA片段的方法。下述实施例主要以冠状病毒、寨卡病毒、埃博拉病毒和艾滋病病毒为例进行论述。
实施例1-RNA病毒靶点过表达载体构建
本实施例为RNA病毒靶点过表达载体的构建，其步骤包括：
1、序列获取和引物设计
从NCBI的Nucleotide数据库Genbank上找到新冠病毒SARS-CoV-2基因序列，然后将病毒的全基因组核苷酸序列和人类全基因组序列进行Blast比对，最终筛选出相似性不小于95％的病毒核苷酸序列片段为病毒RNA靶点序列(下面简称靶点)，新冠病毒SARS-CoV-2筛选出5段与人基因组完全互补配对的序列以及1段与人基因不完全互补配对，寨卡病毒、埃博拉病毒、艾滋病病毒、SARS-CoV病毒和MERS-CoV病毒、其他RNA病毒用同样的方法获取靶点序列。筛选所得的靶点序列如上表1所示。
利用primer5软件分别确定上下游引物，再在上游引物的5’端前面加上保护碱基和EcoRI酶切位点序列(CGGAATTC)，下游引物的5’端前面加上保护碱基和BamHI酶切位点序列(CGGGATCC)。引物委托上海桑尼生物科技有限公司进行合成。部分靶点的引物序列如上表3所示。
2、获取RNA病毒靶点目的片段序列
以新冠病毒靶点序列为例，利用同源重组人工合成病毒靶点片段，根据序列设计的F123与R1引物进行退火后，利用F123和R2与F123和R3进行两轮巢氏PCR，Q5酶扩增目的基因片段，扩增体系和程序如下：
PCR程序：98℃30s；
98℃10s，55～72℃30s，72℃30s/kb，35个循环；
72℃2min。
严重急性呼吸综合征冠状病毒、中东呼吸综合征冠状病毒则利用F1与R1引物进行退火后，利用F2和R2与退火产物进行巢氏PCR获得目的片段。
3、PCR产物的回收、酶切及纯化
将PCR产物进行1％琼脂糖凝胶电泳检测，割胶回收，并使用普通琼脂糖凝胶DNA回收试剂盒(天根生化科技公司)回收目的片段；酶切过程参照NEB网站酶切体系37℃酶切过夜，并采用PCR产物回收试剂盒(天根生化科技公司)纯化回收。
4、连接
利用T4连接酶将酶切后的PCR产物和酶切后的pCDH载体按照如下连接体系连接，16℃过夜。
连接体系
| 试剂 | 体积 |
| PCR产物 | 1μl |
| 酶切后的pCDH载体 | 1μl |
| T4 DNA连接酶缓冲液 | 1μl |
| T4 DNA连接酶 | 1μl |
| H<sub>2</sub>O | 6ul |
| 总计 | 10ul |
5、转化、挑取单克隆连接
(1)将10μl的连接产物加入50μl的DH5α感受态细胞中，冰上孵育30min。
(2)42℃热激感受态细胞90s后，立即放到冰上5min。
(3)在超净工作台中加入300μl不含抗生素的LB液体培养基，37℃恒温摇床中摇菌30min。
(4)菌液1000g离心5min后弃上清，剩50μl菌液，将其均匀涂到氨苄抗性的LB固体平板上，37℃恒温培养箱培养过夜。
(5)从过夜培养的平板上挑取适量单克隆菌落，分别放入加有200μl氨苄抗性LB液体培养基的EP管中，37℃恒温摇床中摇菌2小时后送测序鉴定。最后通过载体PCR可以得到目的条带(图1)。
结果显示：靶点-载体的长度均为200-250bp。图1示出了分别含新型冠状病毒的6个靶点的靶点-载体的电泳结果，其中，HIS1为含SARS-CoV-2-HIS-1的靶点-载体，HIS2为含SARS-CoV-2-HIS-2的靶点-载体，HIS3为含SARS-CoV-2-HIS-3的靶点-载体，HIS4为含SARS-CoV-2-HIS-4的靶点-载体、HIS5为含SARS-CoV-2-HIS-5的靶点-载体、HIS6为含SARS-CoV-2-HIS-6的靶点-载体。
上述同样操作于SARS-CoV病毒、MERS-CoV病毒、寨卡病毒、埃博拉病毒和艾滋病病毒。
实施例2–细胞过表达RNA病毒靶点序列对周围基因表达水平的影响
本实施例对293T细胞中过表达RNA病毒靶点序列对周围基因表达水平进行检测，其步骤简述如下：
1、脂质体法包制慢病毒：依照分子克隆，将SARS-CoV-2、SARS-CoV、MERS-CoV过表达质粒及病毒包装质粒psPAX2和衣壳质粒pMD2.G-VSVG转入293T细胞，48hr和72hr后各收取一次上清，0.45μm滤器过滤细胞碎片后得到慢病毒原液。
2、感染细胞：提前将被感染的细胞(慢病毒原液)铺20万于6cm培养皿中，待第二天细胞贴壁之后进行第一次感染，第三天再重复感染一次；第四天让细胞恢复一天不加入任何刺激；第五天开始对质粒所带的对应杀药标记进行药物筛选。
3、实时荧光定量PCR
(1)总RNA提取
准备106～107细胞，用PBS重悬后离心去除上清，加入1ml Trizol室温裂解5min，然后加入0.2ml氯仿，涡旋震荡仪震荡15s，室温静置2min。4℃离心机离心15min，13,300rpm。转移上层无色水相于另一EP管中。加入等体积异丙醇，涡旋震荡仪充分混合，入4℃离心机离心10min，13,300rpm。倒掉上清，加入DEPC水配制的75％乙醇1ml，上下颠倒至沉淀悬浮起来，入4℃离心机离心5min，13,300rpm。用移液器吸尽上清，室温干燥5～20min，期间观察沉淀形态，待其刚刚变透明时，根据沉淀的量将其溶解于40～100μlDEPC水中。取1μl在Nanodrop上测定其浓度以及OD260/OD280。提取的RNA于-80℃冰箱保存。
(2)逆转录合成cDNA
使用Takara(D2680A)的反转录PCR试剂盒，PCR反应体系和程序如下：
反转录PCR程序：42℃10min，95℃2min。
(3)RT-qPCR
使用Takara实时荧光定量PCR试剂盒检测目的基因转录水平上的表达情况。
实验结果：在过表达靶点序列片段后，该片段的表达水平有上万倍的上调(图2)。其中，与冠状病毒非常相关的ACE2基因在SARS-CoV-HIS、SARS-COV-2-HIS-3和SARS-COV-2-HIS-4片段过表达后被激活(图3)。与新冠病毒相关的透明质酸合成酶家族HAS1(图4)，HAS2(图5)和HAS3(图6)基因也被SARS-CoV-HIS、MERS-CoV-HIS、SARS-COV-2-HIS-3和SARS-COV-2-HIS-4片段显著激活。最后检测SARS-COV-2-HIS-4(图7)，SARS-COV-2-HIS-3(图8)，SARS-COV-2-HIS-1(图9)和SARS-COV-2-HIS-5(图10)片段周围200k以内基因均被显著激活，在不是完全互补配对的片段SARS-CoV-2-HIS-6中得到了同样的结果(图11)，具体基因包括：FBXO15、MYL9、KALRN、ATP8B1、C5AR1、EPAS1等。SARS-COV-HIS-2(图12)和MERS-COV-HIS-2(图13)也具有相同结果，具体为SARS病毒靶点片段周围基因IGF2R的表达增加，MERS病毒靶点片段周围基因IGF2R的表达增加。此外，本实施例还检测了寨卡病毒(图14)、埃博拉病毒(图15)、艾滋病病毒HIV-2(图16)，其结果也相同，具体为：寨卡病毒靶点片段在293T细胞内过表达后周围CNMD、VPS36等16个基因的表达增加；埃博拉病毒靶点片段在293T细胞内过表达后周围VGLL4、TAMM41等15个基因的表达均增加；HIV病毒靶点片段在293T细胞内过表达后周围BMP5、MMP1、ADCYAP1基因的表达增加；HIV2病毒靶点片段在293T细胞内过表达后周围LAPTM4A、LRRC14B等8个基因的表达增加。
上述结果证明构建的载体表达新冠病毒SARS-CoV-2相关miRNA发挥着一定的功能，为之后的研究提供研究基础。
实施例3-RNA病毒靶点miRNA抑制剂(antagomiR)或反义序列对被激活靶基因的抑制作用
本实施例对RNA病毒靶点抑制剂antagomir对激活靶基因的抑制作用进行验证，其包括步骤：
步骤一：制备病毒靶点抑制剂antagomir：将RNA病毒的靶点序列的反向互补序列的3’端进行胆固醇修饰和四个硫代骨架修饰，5’端进行两个硫代骨架修饰，全链进行甲氧基修饰，得到相对应的病毒靶点抑制剂antagomir。
步骤二：采用实施例2的方法制备病毒原液，并采用病毒原液感染细胞，将感染后的细胞分为实验组和对照组两组，其中，实验组为：加入10μM相应病毒靶点抑制剂的感染病毒的细胞液；对照组为：加入10μM感染病毒的细胞液。48小时后将实验组和对照组的细胞液按照实施例4中的实时荧光定量PCR的方法进行试验。
试验结果如图17-20所示，病毒靶点抑制剂可以特异性抑制靶点序列的复制，antagomir可以很好针对靶点序列使得被SARS-CoV-HIS-2(图17)、MERS-CoV-HIS-2(图18)、SARS-CoV-2-HIS-4(图19)和SARS-CoV-2-HIS-3(图20)激活的周围基因有显著下降的趋势，进一步验证了RNA病毒靶点的治疗价值。
本试验还进一步验证了RNA病毒靶点序列的反向互补序列(包括反义DNA和反义RNA序列)以及在RNA病毒的靶点序列的3’端进行胆固醇修饰和四个硫代骨架修饰，5’端进行两个硫代骨架修饰，全链进行甲氧基修饰作为抑制剂对对激活靶基因的抑制作用进行验证。试验结果与抑制剂antagomiR相似，可见，上述三种抑制剂均具有对被激活靶基因的抑制作用。RNA病毒靶点序列的反义RNA或反义DNA可以作为抑制RNA病毒核酸并阻断RNA病毒的重要致病途径，其不同的修饰或不修饰产物为RNA病毒疾病的治疗提供重要的物质基础，其详细序列见表2。
实施例4-靶点所影响的透明质酸升高可由透明质酸抑制剂4-MU降低
本实施例对透明质酸抑制剂4-MU降低靶点所影响的透明质酸升高进行验证，其包括步骤：
采用实施例2的方法制备慢病毒和感染细胞；
更换新鲜培养基，实验组加入100μM的透明质酸抑制剂4-MU，对照组加入4-MU的溶剂DMSO。24hr后收取细胞上清，进行透明质酸ELISA试剂盒(R&D，DY3614-05)进行检测。步骤简述如下：
1)ELISA板包被：100μl/孔Capture Reagent室温包被过夜。
2)封闭：拍板除去Capture Reagent。400μl/孔Wash buffer洗板3次拍干。使用100μl/孔Dilute Reagent封闭1h。
3)洗板孵育样品：400μl/孔Wash buffer洗板3次，加100μl/孔标准品与待测血清(轻症和重症新冠肺炎患者血清100μl用200μl试剂盒中Dilute Reagent稀释成总体积300μl。做3复孔)室温孵育2h。
4)洗板孵育Detect Reagent。400μl/孔Wash buffer洗板3次，加100μl/孔DetectReagent室温孵育2h。
5)洗板孵育HRP。400μl/孔Wash buffer洗板3次，加100μl/孔HRP室温孵育20min。
6)洗板孵育底物。400μl/孔Wash buffer洗板3次，加100μl/孔A、B底物混合液，室温孵育20min。
7)终止显色。加50μl/孔stop solution。15分钟内读取450nm吸光度。
检测结果如表4、表5所示：细胞系293T和MRC5中过表达病毒靶点序列后透明质酸含量均显著上升(表4)。而使用透明质酸抑制剂4-MU可以显著降低由过表达靶点序列产生的透明质酸(表5)。本实施例证明该病毒靶点具有科研研究价值并且4-MU具有成为治疗靶向该改靶点的治疗药物，体现了RNA病毒靶点并发症的治疗价值。
表4-293T和MRC5中过表达病毒靶点细胞透明质酸含量测定
表5-透明质酸抑制剂对过表达病毒靶点透明质酸抑制能力测定
实施例5-血常规指标检测
血常规指标由医院提供，血液中透明质酸使用透明质酸ELISA试剂盒(R&D，DY3614-05)进行检测。其中对比轻症的新冠肺炎患者，重症的新冠肺炎患者血清中HA含量显著升高(表6)。另外，淋巴细胞数目重症新冠肺炎患者显著低于轻症新冠肺炎患者，提示患者免疫细胞随着病情加重而降低；而D-二聚体是纤维蛋白降解产物，D-二聚体水平升高说明体内存在高凝状态和继发性的纤维蛋白溶解亢进。因此，D-二聚体质量浓度对血栓性疾病具有诊断意义。而重症的新冠肺炎患者血清中D-二聚体含量显著高于轻症患者，提示患者凝血风险随着新冠肺炎病情的加重而增加，也提示后续的抗凝治疗存在一定的可行性。
表6-轻重症新冠病毒肺炎患者血液指标
以上结果为RNA病毒靶点序列造成的血液学指标变化成为临床诊断提供依据，体现了RNA病毒靶点的临床诊断价值。并且该靶标具有成为疫苗的可能。另外，制备疫苗过程中，常见的减毒活疫苗仍存在一定的风险有待进一步的优化，将靶点敲除后将大大降低疫苗的致病风险。
以上对本发明的具体实施例进行了详细描述，但其只作为范例，本发明并不限制于以上描述的具体实施例。对于本领域技术人员而言，任何对本发明进行的等同修改和替代也都在本发明的范畴之中。因此，在不脱离本发明的精神和范围下所作的均等变换和修改，都应涵盖在本发明的范围内。
序列表
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<213> 人工序列(Artificial Sequence)
<400> 8
uaacaugcuu aggauaaugg ccuc 24
<210> 9
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 9
aggagaauga caaaaaaaaa aaaaaaa 27
<210> 10
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 10
uuccauuugc acagaguauc uuuu 24
<210> 11
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 11
ugcuguaauu gcuguuguug cugcuguu 28
<210> 12
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 12
gaaaaagaga aaagaaacaa ggg 23
<210> 13
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 13
gggaggaggg aggaagagac ucc 23
<210> 14
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 14
guucuagaga ugcaagacuu gug 23
<210> 15
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 15
acucauucua ccauuuuuua aauug 25
<210> 16
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 16
agauccugug acuucuggac uuuu 24
<210> 17
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 17
aaauauuauu uuuaaaauuu acuu 24
<210> 18
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 18
acuuuuuaaa agaaaagggg gga 23
<210> 19
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 19
gaaaaggaag ggaaaauuuc aaa 23
<210> 20
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 20
aaaugaacaa guagauaaau uag 23
<210> 21
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 21
aaauuauggu accaguuaga gaaa 24
<210> 22
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 22
gaaagaaaaa auauaaauua aaa 23
<210> 23
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 23
auuuaucaag agccauuuaa aaa 23
<210> 24
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 24
uaaaacaggg accaaaagaa ccgu 24
<210> 25
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 25
agaaucagau aaguagaauu aga 23
<210> 26
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 26
aggcagagga agaugaggcc aac 23
<210> 27
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 27
uaucaaaaaa uuaagaaaag guua 24
<210> 28
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 28
ggaucagugg agaaagugag gaggauga 28
<210> 29
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 29
augagagauc uugggggugg gac 23
<210> 30
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 30
gaaaaacuca agaugaaagg aau 23
<210> 31
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 31
auugauuggc uuaaggagaa aaua 24
<210> 32
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 32
aauuguuuac cuauuuauug guuuugug 28
<210> 33
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 33
cugugcugaa ccaggaccag ga 22
<210> 34
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 34
agaugaagca gucaccaacc gc 22
<210> 35
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 35
auuagauuuc aacacaggug cuacauc 27
<210> 36
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 36
uuggaauguu uugcuccucu uua 23
<210> 37
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 37
gaaauuuuau uauuuuguuc agu 23
<210> 38
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 38
uuagcuagau uuacagauuu gga 23
<210> 39
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 39
aacaagagca ggccagugug gugg 24
<210> 40
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 40
uugaggaaaa gggaacccug uaca 24
<210> 41
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 41
ccaggcacug ggaagucagu ggca 24
<210> 42
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 42
aauuaggagu gauaccuuca cuaa 24
<210> 43
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 43
ugagaaaaag gccacugucc uuua 24
<210> 44
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 44
acaaauugga gaaauaguga aaa 23
<210> 45
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 45
gaagcagaga gaaaguagag aag 23
<210> 46
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 46
ucaaaaggag agaacagaug cugg 24
<210> 47
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 47
caaaagaagg cauuaaaaga gga 23
<210> 48
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 48
gagauggacu uugauuucug uga 23
<210> 49
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 49
ggaaauccag ggagguuuug gaa 23
<210> 50
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 50
aaaggaagaa auugaaaccc aga 23
<210> 51
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 51
guggcaggcc cauuacacca cca 23
<210> 52
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 52
aguuuaaauu uauauccaaa auaaauuu 28
<210> 53
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 53
aagaaaaaga uaaauagaac acaaagaauu gacaaaauuu 40
<210> 54
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 54
ucuaagcgaa guaacaacaa gagu 24
<210> 55
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 55
aacagaaaga agcauuauua caucaggcuu cu 32
<210> 56
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 56
ugauuuauau uuacugguau aaaauagu 28
<210> 57
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 57
aacaaacaaa ccagagacac uaaggaaaug ca 32
<210> 58
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 58
auacaaucaa auugaauggc au 22
<210> 59
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 59
agaugacaau ugugaaauua aa 22
<210> 60
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 60
guuauauaug ggaaaugaug gaauuaaca 29
<210> 61
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 61
aaaaaacuaa gugauucaac a 21
<210> 62
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 62
aaauacaaaa aauauacuga auacaa 26
<210> 63
<211> 37
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 63
uuuacauucc uggucaacua ugaaaugaaa cuauugc 37
<210> 64
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 64
cuacaaaaaa augcuaaaag aa 22
<210> 65
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 65
augcugaaca acucaaagaa aa 22
<210> 66
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 66
aggaaaguga aaagauggca aa 22
<210> 67
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 67
aaugaggaaa gugaaaagau ggcaaaaga 29
<210> 68
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 68
caagaaaaaa gauaguauca u 21
<210> 69
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 69
ccauagaaac auuugauaac aaugaagaa 29
<210> 70
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 70
aaaguauaua uuauguuaca aca 23
<210> 71
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 71
augauaacaa caauaaucuc uuu 23
<210> 72
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 72
acuaauacac augauaacaa 20
<210> 73
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 73
ugauaacaac aauaaucucu uugcua 26
<210> 74
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 74
gaaaaggaaa agaagauuuc uug 23
<210> 75
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 75
aauguacagc auccaauaaa aa 22
<210> 76
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 76
uaauuauuuu gaauggccac cccaug 26
<210> 77
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 77
aauuauuuug aauggccacc c 21
<210> 78
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 78
ucuauaaaua auauaacuaa a 21
<210> 79
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 79
uaaauauaga uaaaauauac auua 24
<210> 80
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 80
aaauguuugu uuaauuacau ggauuagua 29
<210> 81
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 81
augguuaaua cauugguuua auuuaua 27
<210> 82
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 82
aacuauauua aaaacuuaug uau 23
<210> 83
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 83
uauagaacau gaaaaauuaa aauuuuc 27
<210> 84
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 84
uagacaauau aacuauauua aaa 23
<210> 85
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 85
aauguuacca uuguuaucua aua 23
<210> 86
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 86
agguaaauua augagagaga auggaguu 28
<210> 87
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 87
uauuuuaaaa ggcagauaau uaga 24
<210> 88
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 88
ggaacuuggu gcauuuuuuu cua 23
<210> 89
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 89
auuuuucuug auugcuuuuc aa 22
<210> 90
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 90
uauucugaaa augguauauu uaa 23
<210> 91
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 91
agccuauuuu cauugaugcc uga 23
<210> 92
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 92
ucaacaaaua uuuacaggca aaa 23
<210> 93
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 93
uuagaaaaau ggaaaaguau aga 23
<210> 94
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 94
aagagcucaa caaauauuua cag 23
<210> 95
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 95
ucuaaauauu cagaaugcac uagagaaa 28
<210> 96
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 96
ugaugggggu ugacggaguu ggggagu 27
<210> 97
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 97
ggggauugga aaggcucucu gug 23
<210> 98
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 98
aaauggagca gaaagaacac ucagg 25
<210> 99
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 99
uggcucgaag agcauggaga ggaa 24
<210> 100
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 100
aggaagggga uugagagacu cac 23
<210> 101
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 101
aaaauagacu ggagauggcc auguggagaa gc 32
<210> 102
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 102
cagcgcaggg gaagaguggg caggcag 27
<210> 103
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 103
aauaagaaaa gcaacauugu gauuuuuaau ua 32
<210> 104
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 104
uaaaaaaagu caaauuuaug auua 24
<210> 105
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 105
cuuuggcauu ucagugauuc agcaaaa 27
<210> 106
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 106
aaaugugcuc cccuuuccug ga 22
<210> 107
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 107
uuuuaaagga guggugaaga agaaaga 27
<210> 108
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 108
aaauaauaua aaugcauuca acu 23
<210> 109
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 109
ggcaggugug guugcucaag cuguaa 26
<210> 110
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 110
uauaacauuu uccugcuucc aa 22
<210> 111
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 111
ucauuggaag auggagcucu uu 22
<210> 112
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 112
cagcuuacuc uuccucagag uucuuu 26
<210> 113
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 113
uuuaugaauu cuacagaaau aaugauaaug 30
<210> 114
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 114
aaagauuaug gaaacuuuuc ug 22
<210> 115
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 115
uugcuguuuu uccaaacacu aga 23
<210> 116
<211> 34
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 116
gucaauccaa auauuggaag aagcagaagu uaau 34
<210> 117
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 117
auguggagac auuccagcac agaggaaac 29
<210> 118
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 118
ucaggcucaa gugaucucuc auuuca 26
<210> 119
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 119
uuauauugaa guuuaugaag uug 23
<210> 120
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 120
agauauagga augugucuga aa 22
<210> 121
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 121
aaaagucaag aaaauuaaau uuaua 25
<210> 122
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 122
uaugccugau aauuuuucau ugg 23
<210> 123
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 123
auaaaggaaa agucaagaaa auu 23
<210> 124
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 124
agagagagag aaaagaaaau ug 22
<210> 125
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 125
uaugccugau aauuuuucau ug 22
<210> 126
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 126
cuguguuuuc uccuagaaug uca 23
<210> 127
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 127
aaagacagga uuucauuauu ugua 24
<210> 128
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 128
uggaugugag aaauacuugg ga 22
<210> 129
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 129
aaaagacagg auuucauuau uu 22
<210> 130
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 130
aaaagacagg auuucauuau uuguau 26
<210> 131
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 131
gacaggauuu cauuauuugu au 22
<210> 132
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 132
aguucucuuu ugacauuuug uuc 23
<210> 133
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 133
ugacauuuug uucuuucuuu g 21
<210> 134
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 134
gaaaauguug uccaacaauc caaucaa 27
<210> 135
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 135
ggaagaaaag acauuaaacu aauu 24
<210> 136
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 136
uaaucuucua uaagucuagu aaa 23
<210> 137
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 137
caggaauccu uguagugaug ggauugu 27
<210> 138
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 138
uauauucaau ggcaaaagaa aacaaau 27
<210> 139
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 139
aaugccuuaa ucucagauaa uuuguuaa 28
<210> 140
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 140
uaauuuguua augaagaaua aaauuaa 27
<210> 141
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 141
aacaaguuuc uccuuaucau aaa 23
<210> 142
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 142
cauaguaucu cuuauaaucc uuuucauuu 29
<210> 143
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 143
auaguaucuc uuauaauccu uuucauuu 28
<210> 144
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 144
uacaaacaug ggcaauucaa aauc 24
<210> 145
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 145
gcucuucuuu ccuuaacaaa ugu 23
<210> 146
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 146
uguuaaacac uuucuuuccu uuu 23
<210> 147
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 147
auaguaucuc uuauaauccu uuu 23
<210> 148
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 148
acaacugaaa caaugcaagg aau 23
<210> 149
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 149
guucaagggc caauuauauc aca 23
<210> 150
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 150
uauaaaauuu ucucaggucu au 22
<210> 151
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 151
agaaauucag gaaaauggaa aaa 23
<210> 152
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 152
cacaaagcuc aagcacguau ugu 23
<210> 153
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 153
cuuguuuucu uucccuuucu uucug 25
<210> 154
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 154
uuucuuuccc uuucuuucug cuuucu 26
<210> 155
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 155
uuuucuuucc cuuucuuucu gcuuucucu 29
<210> 156
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 156
uuucuuuccc uuucuuucug cuu 23
<210> 157
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 157
uuucuuuccc uuucuuucug cuuucu 26
<210> 158
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 158
auauggaugu agauuucauu ug 22
<210> 159
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 159
uuuucuuucc cuuucuuucu gcuuucu 27
<210> 160
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 160
acaucuuuac aauguggaua uuucuuc 27
<210> 161
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 161
uucauacauu cuaaacuuaa uuccagau 28
<210> 162
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 162
gacuacaaga gaaggauggc aga 23
<210> 163
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 163
aauggcaguu augaauauau ua 22
<210> 164
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 164
aagguuguau uuuauuauuu aa 22
<210> 165
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 165
ccuuuuuccu uuucaucacu uuuuuu 26
<210> 166
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 166
caggaaaaaa auggauacua aa 22
<210> 167
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 167
auuauuuuau aaucauuauc uaauua 26
<210> 168
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 168
uauauauaug caaguagcau auauaua 27
<210> 169
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 169
uguuagauuu cuugucauuu uuucc 25
<210> 170
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 170
ccacagcaac augguuucag uau 23
<210> 171
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 171
cuuguuaagu acuugauauc ugu 23
<210> 172
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 172
auucucuuau uaugaauaaa gca 23
<210> 173
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 173
agagagaaag aaagagaauu ggggagu 27
<210> 174
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 174
auauggaugu agauuucauu ug 22
<210> 175
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 175
aacaucuuau uuccuucuuu uc 22
<210> 176
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 176
uuuuuagccc uugcaaagaa cu 22
<210> 177
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 177
cuucauuaag uguuuuuauc ggaaguca 28
<210> 178
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 178
ugcccugacu ucacaggcca uuu 23
<210> 179
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 179
auuaucuuaa gaaagauuaa agaagaauuu g 31
<210> 180
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 180
ucaaagcaaa auagguucag agc 23
<210> 181
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 181
aacuuuuuau ugauccagug cuca 24
<210> 182
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 182
agauaucuuu caaaaaauuu caa 23
<210> 183
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 183
augcauacaa caaugggaau gucauuu 27
<210> 184
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 184
auuguuuaua uuuauuuuca uuu 23
<210> 185
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 185
caacauaaaa aaucaaccau auu 23
<210> 186
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 186
uccucuuuuc uuuuccuuuc uccuucuuu 29
<210> 187
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 187
cagaaaagca guaugagaag ga 22
<210> 188
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 188
uugccugggg aaaggaggca gu 22
<210> 189
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 189
cagaaaagca guaugagaag ga 22
<210> 190
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 190
ucuuuucuuu uccuuucucc uucuuu 26
<210> 191
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 191
guccucuuuu cuuuuccuuu cuccuucuuu 30
<210> 192
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 192
cuuuucuuuu ccuuucuccu uc 22
<210> 193
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 193
cucuuuucuu uuccuuucuc cuucuu 26
<210> 194
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 194
uuaauaagaa uacagauuua uu 22
<210> 195
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 195
ucucugaguu agaaaaugag aaagu 25
<210> 196
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 196
cuuugcauua aaaaaugugu uuga 24
<210> 197
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 197
uuuuauaugu cuagaaaacu uagacacuau a 31
<210> 198
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 198
cuacaggaug uagauuuuga aaaua 25
<210> 199
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 199
ucuuuguauu cuggcuuucc uucuuugguu g 31
<210> 200
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 200
agaagacaca aaaaaaugug uuaacacaaa ac 32
<210> 201
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 201
ucaguguuuu cugacuccaa aguu 24
<210> 202
<211> 29
<212> DNA/RNA
<213> Vitex agnus-castus
<400> 202
uaccaagaaa augaagaagg cucuucuga 29
<210> 203
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 203
uuuacuugcu uauguaaccu uauuuu 26
<210> 204
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 204
uuucucuauu uucucuuguu uuaaac 26
<210> 205
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 205
aagaugacua ucuaaaaugu cagg 24
<210> 206
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 206
auucacugcc uucuucccuc uca 23
<210> 207
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 207
cugucugcua accaguauga aca 23
<210> 208
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 208
agaaaguucu aucaaguuuu uuu 23
<210> 209
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 209
uuucaaauuc cuucucagaa uuc 23
<210> 210
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 210
auuuuguaca gaagguuuuc auaa 24
<210> 211
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 211
auugauuaga aauucaacuu ggaaaaauca aug 33
<210> 212
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 212
ggaugucuuu gucuuucuuu uucuuug 27
<210> 213
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 213
acaccaaagg gaaacucacu gacagaaaac 30
<210> 214
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 214
gacacagaug aagaaacuuc cuuu 24
<210> 215
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 215
uacaacccaa gagagcuuaa ac 22
<210> 216
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 216
aaagaaugaa guaaagguca gca 23
<210> 217
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 217
gugcuauuga ucagacuaau ua 22
<210> 218
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 218
gcuggacugu ggugacagcc uc 22
<210> 219
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 219
caaccucugc acaaaaugag cu 22
<210> 220
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 220
acaauggagc augcaaggaa gca 23
<210> 221
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 221
uagcagguag uauccaagac agagac 26
<210> 222
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 222
aaaaugcuga ggauaugggc aa 22
<210> 223
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 223
caauaaccaa agagaaaaaa gaa 23
<210> 224
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 224
aaucauggaa guuguuuucc cca 23
<210> 225
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 225
aagcaaccag gagauugguu ca 22
<210> 226
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 226
augcaacuga gaucagagca uc 22
<210> 227
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 227
ccagaggaca agagcucuug uu 22
<210> 228
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 228
gaggacgaga uggguggauc aaga 24
<210> 229
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 229
gaggacgaga uggguggauc aagagguc 28
<210> 230
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 230
uuggcucauu cucuguuuuu uuuguuuuuu uu 32
<210> 231
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 231
gaggacgaga uggguggauc aagagguc 28
<210> 232
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 232
cucauucucu guuuuuuuug uuuuuuuu 28
<210> 233
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 233
cuuuauucua aaauauuuuu aaau 24
<210> 234
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 234
augagcccaa gacuucuuuu gau 23
<210> 235
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 235
aagaaacugu gauuuuuaau acuua 25
<210> 236
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 236
aagaaugaua aagcaaagaa aa 22
<210> 237
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 237
uacuuuuaaa gaugcaugcu uucauu 26
<210> 238
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 238
uuuaaaaaau gauaagaaua aa 22
<210> 239
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 239
agaaugauaa agcaaagaaa auguag 26
<210> 240
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 240
uacugaucuc caacucagaa ga 22
<210> 241
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 241
aaaauuugaa agaaugauaa agcaaa 26
<210> 242
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 242
aaaaaugaau gaaaauaugc auucucuuca aaa 33
<210> 243
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 243
aaagcaagaa aaaugaauga aaa 23
<210> 244
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 244
caagaaaaau gaaugaaaau au 22
<210> 245
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 245
aggagaaauc aaaacaaaac caua 24
<210> 246
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 246
gcauucaaua aauacaugcu g 21
<210> 247
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 247
auguaagaac uguaaauaua a 21
<210> 248
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 248
aaaacaaaac cauaaaagua g 21
<210> 249
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 249
aaaggagaaa ucaaaacaaa accauaaaa 29
<210> 250
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 250
uagggagcuc cccacucccg uuuugugac 29
<210> 251
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 251
uauaucaaaa gaaaaugaaa ucaa 24
<210> 252
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 252
gauuaaauuu auaucaaaag aaaaugaa 28
<210> 253
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 253
uauaucaaaa gaaaaugaaa ucaaua 26
<210> 254
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 254
aaagaaaaug aaaucaauag uugagga 27
<210> 255
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 255
uauaucaaaa gaaaaugaaa ucaauag 27
<210> 256
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 256
augaccaaau guauagauug aga 23
<210> 257
<211> 34
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 257
uauaucaaaa gaaaaugaaa ucaauaguug agga 34
<210> 258
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 258
uauaucaaaa gaaaaugaaa ucaaua 26
<210> 259
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 259
uugaaauaag aagauuagau auuuuuaauu 30
<210> 260
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 260
ugauaucauu uucaauuaca ua 22
<210> 261
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 261
aagaaaaaga agauagcaag aa 22
<210> 262
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 262
agcuaaaguu ugguaggaaa acaa 24
<210> 263
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 263
aaaucaagua aaauaacaau aaaugacaua c 31
<210> 264
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 264
cauuaaauuu auacaaacaa acacaaa 27
<210> 265
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 265
agcuaaaguu ugguaggaaa acaa 24
<210> 266
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 266
gaaauauacc auauaaauau gaugu 25
<210> 267
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 267
aaauaagauc agaauuuuau uua 23
<210> 268
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 268
agaauuauau uaauacagua ua 22
<210> 269
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 269
agcauuaaaa cauuagaaau auuaaauaag 30
<210> 270
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 270
agaauuauau uaauacagua uauagu 26
<210> 271
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 271
gaagaauuau ucacauuaau aa 22
<210> 272
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 272
gaagaacaaa cuauuaauaa uu 22
<210> 273
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 273
uaagaucaga auuuuauuua uuacua 26
<210> 274
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 274
uaaaccaaac auuuuuccuu au 22
<210> 275
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 275
auuuuaaaac acuuaaaaau uu 22
<210> 276
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 276
caauauuucu gcuguucaau ucaaugg 27
<210> 277
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 277
uuuuuugggu uuuguuugug uugauacuuu gag 33
<210> 278
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 278
gcaaauuuau cuuaaauuca aguacaua 28
<210> 279
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 279
uaacagacuu ggaaaaauac aauu 24
<210> 280
<211> 37
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 280
auuaccuuca aaaaucuaga acuuuauuaa uucucag 37
<210> 281
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 281
aaaauuaaaa acaaaaauga aagg 24
<210> 282
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 282
cuuauuuuau gucuucuuug uuguuuuu 28
<210> 283
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 283
auuauuaaca acuuauuuuu auuuaaucuu uua 33
<210> 284
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 284
auaaagaaga auauuaacau ugacauua 28
<210> 285
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 285
uuaugaaugu uuuaucauga uuaaagau 28
<210> 286
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 286
cccagcacag agaugucauu ga 22
<210> 287
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 287
agugagaaau gaugauguug aucaga 26
<210> 288
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 288
uucuaaggaa agcaaccaga ag 22
<210> 289
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 289
ugagcaagaa gaaauccuac au 22
<210> 290
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 290
ggaaugagaa gaaagcuaaa uu 22
<210> 291
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 291
uuagaaaugu cuuaagcauu gc 22
<210> 292
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 292
caggacauug aaaaugaaga gaag 24
<210> 293
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 293
aagagaaaga ccugaccaaa ga 22
<210> 294
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 294
acuaagucau auaaaaauac aagaaaaa 28
<210> 295
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 295
aacaauuuga guugauagac aaugaau 27
<210> 296
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 296
aucauguuuc auacuucuag ccauug 26
<210> 297
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 297
gaaacauacu aagaacacag gaa 23
<210> 298
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 298
uuucaccauu accuucucuu cc 22
<210> 299
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 299
aggaagcaaa auuaaacaga gaagaaa 27
<210> 300
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 300
uggaaaauga aagaacuuug ga 22
<210> 301
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 301
aaaacaacac uuggguaaau cagaca 26
<210> 302
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 302
gcugcuggac agucaguggu uu 22
<210> 303
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 303
ggaucaagaa agaagaguuc ucugaga 27
<210> 304
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 304
ggggagacac acaaauucag ac 22
<210> 305
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 305
accaaaugaa aacccagcuc acaagaguca 30
<210> 306
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 306
aaaugagaau guggaaacca ug 22
<210> 307
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 307
agaaauaagg agaguuuggc gc 22
<210> 308
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 308
agaagaguag acggaaagug ga 22
<210> 309
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 309
agaagaguag acggaaagug ga 22
<210> 310
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 310
gaagagagca gggcaagaau caaaacuagg cu 32
<210> 311
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 311
agggcaagcu uucccaaaug uc 22
<210> 312
<211> 34
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 312
ggacaugauu ccagagagga augaacaagg acaa 34
<210> 313
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 313
ggaaauugug aaaauucaau gg 22
<210> 314
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 314
gagucuacau ucucaguuuu guc 23
<210> 315
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 315
gagacagaca guaaaggaaa au 22
<210> 316
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 316
ugaagaaaaa cuaaagaaaa aa 22
<210> 317
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 317
ccagacagca gacuggaagg ca 22
<210> 318
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 318
aacaggaaau cauauugaau uugu 24
<210> 319
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 319
aguaugcaug gaaagauuuu cuuaaug 27
<210> 320
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 320
cagaguuuga auuuuaugau cag 23
<210> 321
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 321
ugaggguaac auuuaauuuu ggg 23
<210> 322
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 322
uuuuuucuuu uugagaaagg gcuucau 27
<210> 323
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 323
agaaaacaac agguguugau gag 23
<210> 324
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 324
uuuuuucuuu uugagaaagg gcu 23
<210> 325
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 325
aaaugaaaga uuuccagaaa uug 23
<210> 326
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 326
acaacagaua caacaaaugc uggugagaau 30
<210> 327
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 327
agugauucau gcugaaauac agu 23
<210> 328
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 328
augagagauc uugggggugg gac 23
<210> 329
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 329
ccaauguauu uauacauuua caagua 26
<210> 330
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 330
aaguucaaug agaaagagaa uagauaugg 29
<210> 331
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 331
uacuuacaug ccaaaucuca a 21
<210> 332
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 332
aguucaauga gaaagagaau a 21
<210> 333
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 333
uacauacuau uaaugugauu ua 22
<210> 334
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 334
uuuuguccuu ccaauugugu ug 22
<210> 335
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 335
gaagcagaga gaaaguagag aag 23
<210> 336
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 336
ucaaaaggag agaacagaug cugg 24
<210> 337
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 337
ucccuggaug gcaagcagaa gca 23
<210> 338
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 338
ccucuaaguu uccuaagguu cu 22
<210> 339
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 339
aacaagagca ggccagugug gugg 24
<210> 340
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 340
uugaggaaaa gggaacccug uaca 24
<210> 341
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 341
ccaggcacug ggaagucagu ggca 24
<210> 342
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 342
aauuaggagu gauaccuuca cuaa 24
<210> 343
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 343
ugagaaaaag gccacugucc uuua 24
<210> 344
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 344
acaaauugga gaaauaguga aaa 23
<210> 345
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 345
auuuuaaaac acuuaaaaau uu 22
<210> 346
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 346
aaaggaagaa auugaaaccc aga 23
<210> 347
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 347
gaugucauca agaaugcaga ugc 23
<210> 348
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 348
acaaaagaug cagaaagagg caag 24
<210> 349
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 349
aauguuauug aguauauaga gaga 24
<210> 350
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 350
cauuugauga ucuggcauuc caacu 25
<210> 351
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 351
gaagggaggc ugauccagaa cagu 24
<210> 352
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 352
ggcacaacug gaguggaguc ugcu 24
<210> 353
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 353
caaaagaaaa gaaagaagag cuc 23
<210> 354
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 354
uccaaauugc uucaaaugaa aa 22
<210> 355
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 355
aauuguacaa aaacccugau ac 22
<210> 356
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 356
augaggaaug gagggaauag cu 22
<210> 357
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 357
auugcuccuu ugcuggaugg au 22
<210> 358
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 358
uuccaaucug aaugaugcaa ca 22
<210> 359
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 359
uaaaagcugc aucaauaggu gu 22
<210> 360
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 360
gggagauuga uccaaaacag ca 22
<210> 361
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 361
agggggaagc ccagauccug ga 22
<210> 362
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 362
ugccacagag gagacacaca aa 22
<210> 363
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 363
gagaaaggaa aguggacaac a 21
<210> 364
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 364
cauaacaaca acaauaauaa cugaa 25
<210> 365
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 365
aggaagggaa aauacaaaaa au 22
<210> 366
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 366
gaggaaauga gaagaaggcu a 21
<210> 367
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 367
cuggagcugc uggagcagca g 21
<210> 368
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 368
ucucaaacuu gcaguugguc 20
<210> 369
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 369
uugacuaugg gagugauguu u 21
<210> 370
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 370
aguuugaauu cauugcugaa g 21
<210> 371
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 371
gaaaaacaag auuucuccca gug 23
<210> 372
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 372
acagggugau gguguccccc 20
<210> 373
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 373
aaauggacca caaacacaga aac 23
<210> 374
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 374
augucuucuu caaucacuuc aac 23
<210> 375
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 375
uacugcuaag gaagcacaag aug 23
<210> 376
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 376
aaaaauugaa acgaacaaau uc 22
<210> 377
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 377
aauaaauaca acauuacccu uu 22
<210> 378
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 378
aagcaagauu aaaaagagag ga 22
<210> 379
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 379
uuagagcauc uguuggaaga au 22
<210> 380
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 380
aacagaggcu gaacaagagg a 21
<210> 381
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 381
ugcagaagga acaggaacgg c 21
<210> 382
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 382
auuguaugga cacaauuaga aac 23
<210> 383
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 383
augagaaacg ugccugagaa aca 23
<210> 384
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 384
uguuuucuuc ugucugaaga 20
<210> 385
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 385
cauauaauua gcaucacaau 20
<210> 386
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 386
acaaaucagc aguuugaacu gaua 24
<210> 387
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 387
gaaagaggua aauuaaaaag 20
<210> 388
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 388
aaguagcagg cucacucugc 20
<210> 389
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 389
agaaggagag aaggaaaaug g 21
<210> 390
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 390
acaaauaccu gcagaaaugc 20
<210> 391
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 391
aaugaaucaa caagaaagaa aa 22
<210> 392
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 392
aaugaaucaa caagaaagaa 20
<210> 393
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 393
gagaaugaag agaaaacucc 20
<210> 394
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 394
auucagugaa auuggaaaau 20
<210> 395
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 395
agaaauacac caagaccaca ua 22
<210> 396
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 396
cuugaacuua gaagcagaua u 21
<210> 397
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 397
acaaugcuau caauuguaau c 21
<210> 398
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 398
acaaugcuau caauuguaau 20
<210> 399
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 399
gaacuucagg acauagaaaa u 21
<210> 400
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 400
gccuuccuuu ccagaaugug 20
<210> 401
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 401
gauaugacuu ugaaagggag 20
<210> 402
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 402
agggguugga auggcugcag 20
<210> 403
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 403
cagaguagaa ugcaauucuc cuca 24
<210> 404
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 404
uuccugcuuu accauaauga cuga 24
<210> 405
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 405
uuucauaaug ucagcaaaua ugca 24
<210> 406
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 406
ggucuacaaa acauacuuug agaa 24
<210> 407
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 407
caaaauuaga gagacagaaa auaga 25
<210> 408
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 408
gaagcaaaac uguuugugcu 20
<210> 409
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 409
uuguuuuuau guggagcuaa uca 23
<210> 410
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 410
cacaaaggac aauaggaaag aaa 23
<210> 411
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 411
uaaagaaauu gaaucaguaa auaa 24
<210> 412
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 412
agugagacac agggaacaga gaaa 24
<210> 413
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 413
cauaugaaag aaugugcaac auc 23
<210> 414
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 414
uucaaugaau caacaaaaaa gaaa 24
<210> 415
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 415
cagcagauaa aagaauaaug gaaaug 26
<210> 416
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 416
aguugauaau aacaacuggu cuggu 25
<210> 417
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 417
agaagaagaa aaagaggacu auuu 24
<210> 418
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 418
cuucccaguu uuggaguguc ugggau 26
<210> 419
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 419
aaauuuaaau aagaaaaugg aagau 25
<210> 420
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 420
aaucuaaugg gaauuuaaua gcuc 24
<210> 421
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 421
augcagaacu uucuuuuuga cuc 23
<210> 422
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 422
acauucuuuu cauguggggc auaa 24
<210> 423
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 423
cuagucaggc uaggcagaug gu 22
<210> 424
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 424
caaagcagaa ugcaguucuc uu 22
<210> 425
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 425
ugcaccaauu aaaauacaga uau 23
<210> 426
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 426
agaguaagag acaacaugac ca 22
<210> 427
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 427
gggaauuggg acaaugguga ug 22
<210> 428
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 428
aaugccuugu uucuacuaau ac 22
<210> 429
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 429
uaagaggauc aggaaugaga au 22
<210> 430
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 430
aucucauuua aggaaugaca ca 22
<210> 431
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 431
agacaaugcu aaggaaauag gg 22
<210> 432
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 432
aaagcaauga aagaguaugg ggag 24
<210> 433
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 433
uuggucugag gaaugugccu gcu 23
<210> 434
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 434
aucaaugaac aaagaggaaa ua 22
<210> 435
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 435
cagagagagg caaauuaaaa ag 22
<210> 436
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 436
cacaaauuga agaugacaga ga 22
<210> 437
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 437
aaacaagaag ugcuuaugag ag 22
<210> 438
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 438
uuuuuuucaa augcaucuau caa 23
<210> 439
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 439
cagaaauucg aagaaauaaa aug 23
<210> 440
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 440
cagccuaauc agaccaaaug aa 22
<210> 441
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 441
ggacggauua agaaagaaga gu 22
<210> 442
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 442
uggaguugau aaggggaagg ga 22
<210> 443
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 443
acagauuuga aauaauugaa gg 22
<210> 444
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 444
ugcaugugua aauggcucuu g 21
<210> 445
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 445
cuuuuccuga aagugccagc a 21
<210> 446
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 446
aagacaagaa auggccagua gg 22
<210> 447
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 447
cugcauuuga agauuuaaga uug 23
<210> 448
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 448
ccauuaucca aaggucuaca aa 22
<210> 449
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 449
ugagacuucc aagaucaaga ug 22
<210> 450
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 450
gcaggagugg auagauucua ca 22
<210> 451
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 451
aaagcaaauu guagaaaaga uu 22
<210> 452
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 452
ugcagggaag aacacagauc uc 22
<210> 453
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 453
ucaaaugcau gaagacauuc uu 22
<210> 454
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 454
agaaguuaua aggaugaugg a 21
<210> 455
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 455
cugccccauc ggugaagcuc c 21
<210> 456
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 456
aauaccagcc uuccauuuca gaau 24
<210> 457
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 457
aaugaaucca aaucaaagga 20
<210> 458
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 458
augccuuguu ucuacuaaua c 21
<210> 459
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 459
ugaguugcca uucaccauug a 21
<210> 460
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 460
auacauugaa guuuuacauu u 21
<210> 461
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 461
gugugauggg aaugguugga guau 24
<210> 462
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 462
auaugcacaa acagaaugug u 21
<210> 463
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 463
uggauuuguu gccaauuuca 20
<210> 464
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 464
auuauaaaag gaaggucuca 20
<210> 465
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 465
ccaaagaggg aagacgaaag 20
<210> 466
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 466
uauauaaaua gaacaggaac au 22
<210> 467
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 467
acaauaaaaa guuggagaaa ca 22
<210> 468
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 468
aaagccaugg aacaaauggc ug 22
<210> 469
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 469
ggucuacaaa acauacuuug agaaa 25
<210> 470
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 470
aauaguuuac uugaauaaua ca 22
<210> 471
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 471
uucaagaugg agaaagggaa ga 22
<210> 472
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 472
aaaagaaaua caccaaaaca gu 22
<210> 473
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 473
aaccuaaauu ucucccagau uu 22
<210> 474
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 474
acaaccuacu uucucaguac aga 23
<210> 475
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 475
aaauucaaac aaggagauca uu 22
<210> 476
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 476
uggucagguu auucuggcau uu 22
<210> 477
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 477
caaccuggaa ccuggaaccu 20
<210> 478
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 478
ccagcacuga gagggugacu gu 22
<210> 479
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 479
gaaaucaacc ugaaugguuu 20
<210> 480
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 480
uuaucaaaua cuugcuauau ac 22
<210> 481
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 481
cuuuucuuaa aaauuccagc gc 22
<210> 482
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 482
agagaaggau auucucuggu c 21
<210> 483
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 483
ggggagacac acaaauucag ac 22
<210> 484
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 484
ugauuauugc ugcuagaaac aua 23
<210> 485
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 485
ugauuauugc ugcuagaaac au 22
<210> 486
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 486
uggagaaagc caacaagaua aaa 23
<210> 487
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 487
acaaagaaca ugaaaaaaac aag 23
<210> 488
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 488
agggcaagcu uucccaaaug ucu 23
<210> 489
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 489
agggcaagcu uucccaaaug uc 22
<210> 490
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 490
ccaaaacuac auacuggugg ga 22
<210> 491
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 491
aggcaaagug gugugugugu gc 22
<210> 492
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 492
ucaaagagaa agacaugacc a 21
<210> 493
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 493
acuuuguaau cccaugaauc c 21
<210> 494
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 494
uuucaggcag aaugaaugca g 21
<210> 495
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 495
gaaacacagg gaacagagaa a 21
<210> 496
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 496
aaggaagauc ucauuugagg a 21
<210> 497
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 497
gauaguaagu ggaagagaug aa 22
<210> 498
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 498
cauaugaaag aaugugcaac au 22
<210> 499
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 499
auaauacuag uaguaacagu aa 22
<210> 500
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 500
uugacugaag auccagauga a 21
<210> 501
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 501
aaaaaugaug accaauucuc a 21
<210> 502
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 502
uauggaauuc ucucuuacug a 21
<210> 503
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 503
aaaaaacaaa gauugaguaa ga 22
<210> 504
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 504
aagcaaccag gagauugguu ca 22
<210> 505
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 505
ccagaggaca agagcucuug uu 22
<210> 506
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 506
gaaagaacau ucuuuucaug ug 22
<210> 507
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 507
cuguaaugag aaugggagac cu 22
<210> 508
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 508
ggaaauugug aaaauucaau gg 22
<210> 509
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 509
uuuugcuuug uguuguuuug cug 23
<210> 510
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 510
aggacuucga gaaauauguu ga 22
<210> 511
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 511
aaacaacaua acaacaacaa uaa 23
<210> 512
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 512
aaaaugcuga ggauaugggc aa 22
<210> 513
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 513
uuucaccauu accuucucuu cc 22
<210> 514
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 514
ucuuauuucu ucagagacaa ug 22
<210> 515
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 515
agagaaaaua cuugaaaauu gug 23
<210> 516
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 516
acagaaaugu cacugagagg ag 22
<210> 517
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 517
aaagggggua gggacaaugg ug 22
<210> 518
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 518
gacuacagau auacauauag au 22
<210> 519
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 519
gaaaaaggag agugagagac aa 22
<210> 520
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 520
uagauauaaa ugugaaagau ua 22
<210> 521
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 521
ucagacagcu gcccagaggg ca 22
<210> 522
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 522
acuuaccagu cucaucuucu a 21
<210> 523
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 523
uuuucuaucc cucagaaaau cc 22
<210> 524
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 524
cuuugaucuc gggcuugaga 20
<210> 525
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 525
ucucucugcc uuguaguugg 20
<210> 526
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 526
uauaacuuau uacuucagaa 20
<210> 527
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 527
agaaaucaua ucaaauccuu 20
<210> 528
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 528
uucagacaga ucagaccuca 20
<210> 529
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 529
aauauccaga augguuucug 20
<210> 530
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 530
aagucaacau gaaaaaaaca g 21
<210> 531
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 531
ugaaaaaaac aagaucuuaa 20
<210> 532
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 532
gggggguucu uuuugaaaaa 20
<210> 533
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 533
gagauggcca aggugggaga 20
<210> 534
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 534
uuuuuaccaa uaguagaggg 20
<210> 535
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 535
gugcuccuca ugaaaugucu gu 22
<210> 536
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 536
uaccaccuua aauaucagag 20
<210> 537
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 537
cucagccaua aaaaugaacg 20
<210> 538
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 538
auugcagaaa guuucuccaa aa 22
<210> 539
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 539
agacuggacc agcuauggaa uc 22
<210> 540
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 540
auguaaucac cuuauacaug aac 23
<210> 541
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 541
ggaaggacuu gguaaaguuc 20
<210> 542
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 542
aaauccugag gcacuucaac au 22
<210> 543
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 543
gucugucauc ucacuggauc 20
<210> 544
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 544
ugggcacagu ugucacugcu 20
<210> 545
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 545
aaacauugca gacaggauag 20
<210> 546
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 546
uguaauucua gccugagucu 20
<210> 547
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 547
ccaggaaagu cuucagagga u 21
<210> 548
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 548
uaaaagaucu uuucuugucu 20
<210> 549
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 549
agacaaauaa ggucaggaga 20
<210> 550
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 550
agacaacacc cacuccuucu 20
<210> 551
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 551
uagguucaag ucugccagau aca 23
<210> 552
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 552
cuuaccaguc ucaucuucua c 21
<210> 553
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 553
ggccuugcuc uucagagagg 20
<210> 554
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 554
caugcagcua gaaccaugac 20
<210> 555
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 555
ggggaagaaa agugguaggc a 21
<210> 556
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 556
acaggauaga gcagauuuuu 20
<210> 557
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 557
uugaaaauga accuugauga 20
<210> 558
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 558
caugagcaag aucuuuguca a 21
<210> 559
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 559
ucuugugaca uuuuuaccaa u 21
<210> 560
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 560
caggaacaca agaaccaaag 20
<210> 561
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 561
uucacauuaa aaaagugaua 20
<210> 562
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 562
cuguuggaau ggccaggaug 20
<210> 563
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 563
aagguggaga acucagaguu u 21
<210> 564
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 564
gcauuuggaa gguaucuugc 20
<210> 565
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 565
cucuauuucu ugcacuugug 20
<210> 566
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 566
aagaagagac cauguguagu uau 23
<210> 567
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 567
auaaugcauu uggaagguau 20
<210> 568
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 568
cuaugaaguc aucaaaauau 20
<210> 569
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 569
uucucauuuu uguuguuuau uu 22
<210> 570
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 570
auaacagacc uauaacuuau 20
<210> 571
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 571
agagagacac aaggcuaaga 20
<210> 572
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 572
uuaguccaga gagcagaaaa 20
<210> 573
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 573
cacugccucc uucagcaauc a 21
<210> 574
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 574
uaugaaguca ucaaaauauu 20
<210> 575
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 575
cauuaaaaaa gugauagaua 20
<210> 576
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 576
agagagcauc caaagggagu g 21
<210> 577
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 577
aaaaaaugua ccagguguga 20
<210> 578
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 578
aacaugagca agaucuuugu 20
<210> 579
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 579
aaucacauuc uuucaccaga a 21
<210> 580
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 580
ccucacucuu auuucaucca 20
<210> 581
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 581
cauucacuuu guaggaugcu 20
<210> 582
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 582
aucagaaagg cuuuauauga c 21
<210> 583
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 583
uguauuuaua aaagacaagg u 21
<210> 584
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 584
cucauuuuug uuguuuauuu 20
<210> 585
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 585
ugccaagcuu guguucaaca 20
<210> 586
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 586
ugggcucuga caggaggcau g 21
<210> 587
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 587
aaguuaauua ccuuuacauu 20
<210> 588
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 588
uacuaugaug uaucuaucua 20
<210> 589
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 589
aggaggguau ucuucuguau 20
<210> 590
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 590
gaacccagag gaacccccac 20
<210> 591
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 591
cacugccucc uucagcaauc a 21
<210> 592
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 592
agagcucaag aaggagacaa 20
<210> 593
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 593
aagaggggcu ccucuaugaa 20
<210> 594
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 594
ucuacugcuu uaggugacgu 20
<210> 595
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 595
agaugggugg aucaagaggu 20
<210> 596
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 596
aacggugacg aggcugagga 20
<210> 597
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 597
cagaggaugu auuuucuguc 20
<210> 598
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 598
cacauccacu gccuccuuca 20
<210> 599
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 599
agggaugucu ugugacauuu uu 22
<210> 600
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 600
cuucagaaag caagucauuc ua 22
<210> 601
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 601
uacaucucag ccauaaaaau g 21
<210> 602
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 602
uuacugagug caggggcccu ga 22
<210> 603
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 603
ucaacuuucc caacccucca 20
<210> 604
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 604
cagagggaca gggagggagg u 21
<210> 605
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 605
agucagaacu uggaaugaga u 21
<210> 606
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 606
ucaaagauua gagucaacag a 21
<210> 607
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 607
caugaacugg guauacaagu u 21
<210> 608
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 608
cugaugacau gcuggagaag a 21
<210> 609
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 609
uggucacgug uucaaucuca u 21
<210> 610
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 610
uuaugaagac uguucaggac u 21
<210> 611
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 611
cugguggaga uaaaacguac uga 23
<210> 612
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 612
uugauuguuu uucucauuuu 20
<210> 613
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 613
ugguuucugg ggcugugccu c 21
<210> 614
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 614
gagccagggc aggagacagc 20
<210> 615
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 615
ggguucuuuu ugaaaaaaaa 20
<210> 616
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 616
attctagagc tagcgaattc tcatcaactt gtatgatgtg ttacaaacgt aatagagca 59
<210> 617
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 617
gaccttctaa caccattaac aatagttgta cattcgactc ttgttgctct attacgttt 59
<210> 618
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 618
gtagtttgca aaagccttta cctccattag catagacata aaaggacctt ctaacacca 59
<210> 619
<211> 57
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 619
tccttcgcgg ccgcggatca caattaacac aattccaatt gtgtagtttg caaaagc 57
<210> 620
<211> 57
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 620
attctagagc tagcgaattc aacaacatta tcaacaatgc aagagatggt tgtgttc 57
<210> 621
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 621
aaccattagt ttggctgctg ttgtaagagg tattatgttc aagggaacac aaccatctc 59
<210> 622
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 622
gtaccatcac acgtattttt atatgtgtta tagtctggta tgacaaccat tagtttggc 59
<210> 623
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 623
tccttcgcgg ccgcggatcc aatgctgatg cataagtaaa tgttgtacca tcacacgta 59
<210> 624
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 624
attctagagc tagcgaattc cttaacaaag ttgttagtac aactactaac atagttaca 59
<210> 625
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 625
aagaaataag gcatataatt agtacaaaca cggtttaaac accgtgtaac tatgttagt 59
<210> 626
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 626
aatttgtact tctagtaaaa gtacacaatt gtagcaataa agtaaagaaa taaggcata 59
<210> 627
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 627
tccttcgcgg ccgcggatcc tcggcataga tgctttaatt ctagaatttg tacttctag 59
<210> 628
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 628
attctagagc tagcgaattc ggagtacgat cgagtgtaca gtgaacaatg ctagggaga 59
<210> 629
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 629
actaaaatta attttacaca ttagggctct tccatatagg cagctctccc tagcattgt 59
<210> 630
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 630
actaaaatta attttacaca ttagggctct tccatatagg cagctctccc tagcattgt 59
<210> 631
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 631
tccttcgcgg ccgcggatcc tttttttttt tttttttttt ttttgtcatt ctcctaaga 59
<210> 632
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 632
attctagagc tagcgaattc gttaataatt ggttgaagca gttaattaaa gttacactt 59
<210> 633
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 633
acaggtgtta ttaaatagaa aatagcagca acaaaaagga acacaagtgt aactttaat 59
<210> 634
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 634
ctatgatttc acttgaaaag tcagtatgtt tagacatgac atgaacaggt gttattaaa 59
<210> 635
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 635
tccttcgcgg ccgcggatcc caccaccatc aatagccttg tatcctatga tttcacttg 59
<210> 636
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 636
ctccctctgg aatttggtgc ctcagctgaa acagttcgag ttgaggaaga agaagagga 59
<210> 637
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 637
tggctcaatc tctgattgct cagtagtatc atccagccag tcttcctctt cttcttcct 59
<210> 638
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 638
attctagagc tagcgaattc ctccctctgg aatttggtgc 40
<210> 639
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 639
tccttcgcgg ccgcggatca tggctcaatc tctgattgct 40
<210> 640
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 640
tatgggttgg gattatccaa aatgtgacag agccatgcct aacatgctta ggataatgg 59
<210> 641
<211> 58
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 641
aagttacagc aagtgttatg tttgcgagca agaacaagag aggccattat cctaagca 58
<210> 642
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 642
attctagagc tagcgaattc tatgggttgg gattatccaa 40
<210> 643
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 643
tccttcgcgg ccgcggatca aagttacagc aagtgttatg 40
<210> 644
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 644
gtgttggctg gactgctggc ttatcctcct ttgctgctat tccatttgca cagagtatc 59
<210> 645
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 645
gaaagaacct gttgagtaat gccaacaccg tttaacctat aaaagatact ctgtgcaaa 59
<210> 646
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 646
attctagagc tagcgaattc gtgttggctg gactgctggc 40
<210> 647
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 647
tccttcgcgg ccgcggatca gaaagaacct gttgagtaat 40
<210> 648
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 648
aataaagtaa aacgtgcttt tgcagattac acccagtgtg ctgtaattgc tgttgttgc 59
<210> 649
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 649
gtatagaggt aacaaagcag atgcacaagc tattaagaac agcagcaaca acagcaatt 59
<210> 650
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 650
attctagagc tagcgaattc aataaagtaa aacgtgcttt 40
<210> 651
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 651
tccttcgcgg ccgcggatca gtatagaggt aacaaagcag 40
<210> 652
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 652
tgagaggaga gtgccagagt tgtgtgtaca acatgatggg aaaaagagaa aagaaacaa 59
<210> 653
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 653
tataccagat ggcgcggctg cccttggcct ttccaaattc cccttgtttc ttttctctt 59
<210> 654
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 654
gaagattcta gagctagcga attctgagag gagagtgcca gagtt 45
<210> 655
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 655
cagatccttc gcggccgcgg atcctatacc agatggcgcg gctgc 45
<210> 656
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 656
gtgatcaaaa atgggagtta tgttagtgcc atcacccaag ggaggaggga ggaagagac 59
<210> 657
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 657
ctgcttcttc ttcagcatcg aaggctcgaa gcactcaaca ggagtctctt cctccctcc 59
<210> 658
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 658
gaagattcta gagctagcga attcgtgatc aaaaatggga gttat 45
<210> 659
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 659
cagatccttc gcggccgcgg atccctgctt cttcttcagc atcga 45
<210> 660
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 660
ctagtggtgc aactcattcg gaatatggag gctgaggaag ttctagagat gcaagactt 59
<210> 661
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 661
ctgcaaccag ttggtcactt tctctgacct ccgcagcagc cacaagtctt gcatctcta 59
<210> 662
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 662
gaagattcta gagctagcga attcctagtg gtgcaactca ttcgg 45
<210> 663
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 663
cagatccttc gcggccgcgg atccctgcaa ccagttggtc acttt 45
<210> 664
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 664
aatactccac caacagatga tgtatcaagt cctcaccgac tcattctacc attttttaa 59
<210> 665
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 665
ttcttgggca tcttgatcat gtgcatggtt gtgatttccc aatttaaaaa atggtagaa 59
<210> 666
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 666
gaagattcta gagctagcga attcaatact ccaccaacag atgat 45
<210> 667
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 667
cagatccttc gcggccgcgg atccttcttg ggcatcttga tcatg 45
<210> 668
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 668
ttttctaaat ccagaaaagt gtttttatcg aaacttcgga gatcctgtga cttctggac 59
<210> 669
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 669
tctttcatgt taaccatttc taggtacacc cgtagctgga aaagtccaga agtcacagg 59
<210> 670
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 670
gaagattcta gagctagcga attcttttct aaatccagaa aagtg 45
<210> 671
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 671
cagatccttc gcggccgcgg atcctctttc atgttaacca tttct 45
<210> 672
<211> 46
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 672
gaagattcta gagctagcga attcagatct gagagagaaa aatctc 46
<210> 673
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 673
cagatccttc gcggccgcgg atcctattat taattgctca tttaa 45
<210> 674
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 674
agatctgaga gagaaaaatc tcagggttac tctaaggaga aatattattt ttaaaattt 59
<210> 675
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 675
tattattaat tgctcattta agataagtgg tcagcattca agtaaatttt aaaaataat 59
<210> 676
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 676
tttaagacca atgacttaca aggcagctgt agatcttagc cactttttaa aagaaaagg 59
<210> 677
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 677
atatcttgtc ttctttggga gtgaattagc ccttccagtc cccccttttc ttttaaaaa 59
<210> 678
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 678
gaagattcta gagctagcga attctttaag accaatgact taca 44
<210> 679
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 679
cagatccttc gcggccgcgg atccatatct tgtcttcttt ggga 44
<210> 680
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 680
aagaaaaaat aaaagcatta gtagaaattt gtacagagat ggaaaaggaa gggaaaatt 59
<210> 681
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 681
caaatactgg agtattgtat ggattttcag gcccaatttt tgaaattttc ccttccttt 59
<210> 682
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 682
gaagattcta gagctagcga attcaagaaa aaataaaagc atta 44
<210> 683
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 683
cagatccttc gcggccgcgg atcccaaata ctggagtatt gtat 44
<210> 684
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 684
ggtctatctg gcatgggtac cagcacacaa aggaattgga ggaaatgaac aagtagata 59
<210> 685
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 685
ccatctaaaa atagtacttt cctgattcca gcactgacta atttatctac ttgttcatt 59
<210> 686
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 686
gaagattcta gagctagcga attcggtcta tctggcatgg gtac 44
<210> 687
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 687
cagatccttc gcggccgcgg atccccatct aaaaatagta cttt 44
<210> 688
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 688
cctgagtggg agtttgttaa tacccctccc ttagtgaaat tatggtacca gttagagaa 59
<210> 689
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 689
tgccccatct acatagaagg tttctgctcc tactatgggt tctttctcta actggtacc 59
<210> 690
<211> 45
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 690
gaagattcta gagctagcga attccctgag tgggagtttg ttaat 45
<210> 691
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 691
cagatccttc gcggccgcgg atcctgcccc atctacatag aagg 44
<210> 692
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 692
ggagaattag atcgatggga aaaaattcgg ttaaggccag ggggaaagaa aaaatataa 59
<210> 693
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 693
gaatcgttct agctccctgc ttgcccatac tatatgtttt aatttatatt ttttctttc 59
<210> 694
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 694
gaagattcta gagctagcga attcggagaa ttagatcgat ggga 44
<210> 695
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 695
cagatccttc gcggccgcgg atccgaatcg ttctagctcc ctgc 44
<210> 696
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 696
cagaagcagg ggcaaggcca atggacatat caaatttatc aagagccatt taaaaatct 59
<210> 697
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 697
attagtgtgg gcacccctca ttcttgcata ttttcctgtt ttcagatttt taaatggct 59
<210> 698
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 698
gaagattcta gagctagcga attccagaag caggggcaag gcca 44
<210> 699
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 699
cagatccttc gcggccgcgg atccattagt gtgggcaccc ctca 44
<210> 700
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 700
aagtgtgtca gaaagtacaa cccaactaac atcttagaca taaaacaggg accaaaaga 59
<210> 701
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 701
cctcaagctt ttgtagaacc tgtctacata gctttggaac ggttcttttg gtccctgtt 59
<210> 702
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 702
gaagattcta gagctagcga attcaagtgt gtcagaaagt acaa 44
<210> 703
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 703
cagatccttc gcggccgcgg atcccctcaa gcttttgtag aacc 44
<210> 704
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 704
caaagccagg gagtagtaga agcaatgaat caccacctaa agaatcagat aagtagaat 59
<210> 705
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 705
tgccatcagt actattgttt ctattgtatt tgcctgttct ctaattctac ttatctgat 59
<210> 706
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 706
gaagattcta gagctagcga attccaaagc cagggagtag taga 44
<210> 707
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 707
cagatccttc gcggccgcgg atcctgccat cagtactatt gttt 44
<210> 708
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 708
gggtggctgt ggaagctagt atcagtagaa ctctcacaag aggcagagga agatgaggc 59
<210> 709
<211> 59
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 709
atcatcatgt ctgcttgttt gtgctgggtg tactaagcag ttggcctcat cttcctctg 59
<210> 710
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 710
gaagattcta gagctagcga attcgggtgg ctgtggaagc tagt 44
<210> 711
<211> 44
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 711
cagatccttc gcggccgcgg atccatcatc atgtctgctt gttt 44
<210> 712
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 712
acagauacga uuaccuccau uuccga 26
<210> 713
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 713
auauugugua uauuuuuaug caca 24
<210> 714
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 714
aauauacgga auaaagaaau gaaa 24
<210> 715
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 715
uccucuuacu guuuuuuuuu uuuuuuu 27
<210> 716
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 716
aacaacgacg auaaaagaua aauu 24
<210> 717
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 717
guacuucuuu guuaaauauu aaaugaau 28
<210> 718
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 718
cucaacuccu ucuucuucuc cuucugacc 29
<210> 719
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 719
auuguacgaa uccuauuacc ggag 24
<210> 720
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 720
uccucuuacu guuuuuuuuu uuuuuuu 27
<210> 721
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 721
aagguaaacg ugucucauag aaaa 24
<210> 722
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 722
acgacauuaa cgacaacaac gacgacaa 28
<210> 723
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 723
cuuuuucucu uuucuuuguu ccc 23
<210> 724
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 724
cccuccuccc uccuucucug agg 23
<210> 725
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 725
caagaucucu acguucugaa cac 23
<210> 726
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 726
ugaguaagau gguaaaaaau uuaac 25
<210> 727
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 727
ucuaggacac ugaagaccug aaaa 24
<210> 728
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 728
uuuauaauaa aaauuuuaaa ugaa 24
<210> 729
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 729
ugaaaaauuu ucuuuucccc ccu 23
<210> 730
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 730
cuuuuccuuc ccuuuuaaag uuu 23
<210> 731
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 731
uuuacuuguu caucuauuua auc 23
<210> 732
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 732
uuuaauacca uggucaaucu cuuu 24
<210> 733
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 733
cuuucuuuuu uauauuuaau uuu 23
<210> 734
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 734
uaaauaguuc ucgguaaauu uuu 23
<210> 735
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 735
auuuuguccc ugguuuucuu ggca 24
<210> 736
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 736
ucuuagucua uucaucuuaa ucu 23
<210> 737
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 737
uccgucuccu ucuacuccgg uug 23
<210> 738
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 738
auaguuuuuu aauucuuuuc caau 24
<210> 739
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 739
ccuagucacc ucuuucacuc cuccuacu 28
<210> 740
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 740
uacucucuag aacccccacc cug 23
<210> 741
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 741
cuuuuugagu ucuacuuucc uua 23
<210> 742
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 742
uaacuaaccg aauuccucuu uuau 24
<210> 743
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 743
uuaacaaaug gauaaauaac caaaacac 28
<210> 744
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 744
gacacgacuu gguccugguc cu 22
<210> 745
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 745
ucuacuucgu cagugguugg cg 22
<210> 746
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 746
uaaucuaaag uuguguccac gauguag 27
<210> 747
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 747
aaccuuacaa aacgaggaga aau 23
<210> 748
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 748
cuuuaaaaua auaaaacaag uca 23
<210> 749
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 749
aaucgaucua aaugucuaaa ccu 23
<210> 750
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 750
uuguucucgu ccggucacac cacc 24
<210> 751
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 751
aacuccuuuu cccuugggac augu 24
<210> 752
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 752
gguccgugac ccuucaguca ccgu 24
<210> 753
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 753
uuaauccuca cuauggaagu gauu 24
<210> 754
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 754
acucuuuuuc cggugacagg aaau 24
<210> 755
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 755
uguuuaaccu cuuuaucacu uuu 23
<210> 756
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 756
cuucgucucu cuuucaucuc uuc 23
<210> 757
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 757
aguuuuccuc ucuugucuac gacc 24
<210> 758
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 758
guuuucuucc guaauuuucu ccu 23
<210> 759
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 759
cucuaccuga aacuaaagac acu 23
<210> 760
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 760
ccuuuagguc ccuccaaaac cuu 23
<210> 761
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 761
uuuccuucuu uaacuuuggg ucu 23
<210> 762
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 762
caccguccgg guaauguggu ggu 23
<210> 763
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 763
ucaaauuuaa auauagguuu uauuuaaa 28
<210> 764
<211> 40
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 764
uucuuuuucu auuuaucuug uguuucuuaa cuguuuuaaa 40
<210> 765
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 765
agauucgcuu cauuguuguu cuca 24
<210> 766
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 766
uugucuuucu ucguaauaau guaguccgaa ga 32
<210> 767
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 767
acuaaauaua aaugaccaua uuuuauca 28
<210> 768
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 768
uuguuuguuu ggucucugug auuccuuuac gu 32
<210> 769
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 769
uauguuaguu uaacuuaccg ua 22
<210> 770
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 770
ucuacuguua acacuuuaau uu 22
<210> 771
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 771
caauauauac ccuuuacuac cuuaauugu 29
<210> 772
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 772
uuuuuugauu cacuaaguug u 21
<210> 773
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 773
uuuauguuuu uuauaugacu uauguu 26
<210> 774
<211> 37
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 774
aaauguaagg accaguugau acuuuacuuu gauaacg 37
<210> 775
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 775
gauguuuuuu uacgauuuuc uu 22
<210> 776
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 776
uacgacuugu ugaguuucuu uu 22
<210> 777
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 777
uccuuucacu uuucuaccgu uu 22
<210> 778
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 778
uuacuccuuu cacuuuucua ccguuuucu 29
<210> 779
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 779
guucuuuuuu cuaucauagu a 21
<210> 780
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 780
gguaucuuug uaaacuauug uuacuucuu 29
<210> 781
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 781
uuucauauau aauacaaugu ugu 23
<210> 782
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 782
uacuauuguu guuauuagag aaa 23
<210> 783
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 783
ugauuaugug uacuauuguu 20
<210> 784
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 784
acuauuguug uuauuagaga aacgau 26
<210> 785
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 785
cuuuuccuuu ucuucuaaag aac 23
<210> 786
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 786
uuacaugucg uagguuauuu uu 22
<210> 787
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 787
auuaauaaaa cuuaccggug ggguac 26
<210> 788
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 788
uuaauaaaac uuaccggugg g 21
<210> 789
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 789
agauauuuau uauauugauu u 21
<210> 790
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 790
auuuauaucu auuuuauaug uaau 24
<210> 791
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 791
uuuacaaaca aauuaaugua ccuaaucau 29
<210> 792
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 792
uaccaauuau guaaccaaau uaaauau 27
<210> 793
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 793
uugauauaau uuuugaauac aua 23
<210> 794
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 794
auaucuugua cuuuuuaauu uuaaaag 27
<210> 795
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 795
aucuguuaua uugauauaau uuu 23
<210> 796
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 796
uuacaauggu aacaauagau uau 23
<210> 797
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 797
uccauuuaau uacucucucu uaccucaa 28
<210> 798
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 798
auaaaauuuu ccgucuauua aucu 24
<210> 799
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 799
ccuugaacca cguaaaaaaa gau 23
<210> 800
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 800
uaaaaagaac uaacgaaaag uu 22
<210> 801
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 801
auaagacuuu uaccauauaa auu 23
<210> 802
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 802
ucggauaaaa guaacuacgg acu 23
<210> 803
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 803
aguuguuuau aaauguccgu uuu 23
<210> 804
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 804
aaucuuuuua ccuuuucaua ucu 23
<210> 805
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 805
uucucgaguu guuuauaaau guc 23
<210> 806
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 806
agauuuauaa gucuuacgug aucucuuu 28
<210> 807
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 807
acuaccccca acugccucaa ccccuca 27
<210> 808
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 808
ccccuaaccu uuccgagaga cac 23
<210> 809
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 809
uuuaccucgu cuuucuugug agucc 25
<210> 810
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 810
accgagcuuc ucguaccucu ccuu 24
<210> 811
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 811
uccuuccccu aacucucuga gug 23
<210> 812
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 812
uuuuaucuga ccucuaccgg uacaccucuu cg 32
<210> 813
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 813
gucgcguccc cuucucaccc guccguc 27
<210> 814
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 814
uuauucuuuu cguuguaaca cuaaaaauua au 32
<210> 815
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 815
auuuuuuuca guuuaaauac uaau 24
<210> 816
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 816
gaaaccguaa agucacuaag ucguuuu 27
<210> 817
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 817
uuuacacgag gggaaaggac cu 22
<210> 818
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 818
aaaauuuccu caccacuucu ucuuucu 27
<210> 819
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 819
uuuauuauau uuacguaagu uga 23
<210> 820
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 820
ccguccacac caacgaguuc gacauu 26
<210> 821
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 821
auauuguaaa aggacgaagg uu 22
<210> 822
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 822
aguaaccuuc uaccucgaga aa 22
<210> 823
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 823
gucgaaugag aaggagucuc aagaaa 26
<210> 824
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 824
aaauacuuaa gaugucuuua uuacuauuac 30
<210> 825
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 825
uuucuaauac cuuugaaaag ac 22
<210> 826
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 826
aacgacaaaa agguuuguga ucu 23
<210> 827
<211> 34
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 827
caguuagguu uauaaccuuc uucgucuuca auua 34
<210> 828
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 828
uacaccucug uaaggucgug ucuccuuug 29
<210> 829
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 829
aguccgaguu cacuagagag uaaagu 26
<210> 830
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 830
aauauaacuu caaauacuuc aac 23
<210> 831
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 831
ucuauauccu uacacagacu uu 22
<210> 832
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 832
uuuucaguuc uuuuaauuua aauau 25
<210> 833
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 833
auacggacua uuaaaaagua acc 23
<210> 834
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 834
uauuuccuuu ucaguucuuu uaa 23
<210> 835
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 835
ucucucucuc uuuucuuuua ac 22
<210> 836
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 836
auacggacua uuaaaaagua ac 22
<210> 837
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 837
gacacaaaag aggaucuuac agu 23
<210> 838
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 838
uuucuguccu aaaguaauaa acau 24
<210> 839
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 839
accuacacuc uuuaugaacc cu 22
<210> 840
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 840
uuuucugucc uaaaguaaua aa 22
<210> 841
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 841
uuuucugucc uaaaguaaua aacaua 26
<210> 842
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 842
cuguccuaaa guaauaaaca ua 22
<210> 843
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 843
ucaagagaaa acuguaaaac aag 23
<210> 844
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 844
acuguaaaac aagaaagaaa c 21
<210> 845
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 845
cuuuuacaac agguuguuag guuaguu 27
<210> 846
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 846
ccuucuuuuc uguaauuuga uuaa 24
<210> 847
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 847
auuagaagau auucagauca uuu 23
<210> 848
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 848
guccuuagga acaucacuac ccuaaca 27
<210> 849
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 849
auauaaguua ccguuuucuu uuguuua 27
<210> 850
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 850
uuacggaauu agagucuauu aaacaauu 28
<210> 851
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 851
auuaaacaau uacuucuuau uuuaauu 27
<210> 852
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 852
uuguucaaag aggaauagua uuu 23
<210> 853
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 853
guaucauaga gaauauuagg aaaaguaaa 29
<210> 854
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 854
uaucauagag aauauuagga aaaguaaa 28
<210> 855
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 855
auguuuguac ccguuaaguu uuag 24
<210> 856
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 856
cgagaagaaa ggaauuguuu aca 23
<210> 857
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 857
acaauuugug aaagaaagga aaa 23
<210> 858
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 858
uaucauagag aauauuagga aaa 23
<210> 859
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 859
uguugacuuu guuacguucc uua 23
<210> 860
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 860
caaguucccg guuaauauag ugu 23
<210> 861
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 861
auauuuuaaa agaguccaga ua 22
<210> 862
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 862
ucuuuaaguc cuuuuaccuu uuu 23
<210> 863
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 863
guguuucgag uucgugcaua aca 23
<210> 864
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 864
gaacaaaaga aagggaaaga aagac 25
<210> 865
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 865
aaagaaaggg aaagaaagac gaaaga 26
<210> 866
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 866
aaaagaaagg gaaagaaaga cgaaagaga 29
<210> 867
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 867
aaagaaaggg aaagaaagac gaa 23
<210> 868
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 868
aaagaaaggg aaagaaagac gaaaga 26
<210> 869
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 869
uauaccuaca ucuaaaguaa ac 22
<210> 870
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 870
aaaagaaagg gaaagaaaga cgaaaga 27
<210> 871
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 871
uguagaaaug uuacaccuau aaagaag 27
<210> 872
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 872
aaguauguaa gauuugaauu aaggucua 28
<210> 873
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 873
cugauguucu cuuccuaccg ucu 23
<210> 874
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 874
uuaccgucaa uacuuauaua au 22
<210> 875
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 875
uuccaacaua aaauaauaaa uu 22
<210> 876
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 876
ggaaaaagga aaaguaguga aaaaaa 26
<210> 877
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 877
guccuuuuuu uaccuaugau uu 22
<210> 878
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 878
uaauaaaaua uuaguaauag auuaau 26
<210> 879
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 879
auauauauac guucaucgua uauauau 27
<210> 880
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 880
acaaucuaaa gaacaguaaa aaagg 25
<210> 881
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 881
ggugucguug uaccaaaguc aua 23
<210> 882
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 882
gaacaauuca ugaacuauag aca 23
<210> 883
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 883
uaagagaaua auacuuauuu cgu 23
<210> 884
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 884
ucucucuuuc uuucucuuaa ccccuca 27
<210> 885
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 885
uauaccuaca ucuaaaguaa ac 22
<210> 886
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 886
uuguagaaua aaggaagaaa ag 22
<210> 887
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 887
aaaaaucggg aacguuucuu ga 22
<210> 888
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 888
gaaguaauuc acaaaaauag ccuucagu 28
<210> 889
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 889
acgggacuga aguguccggu aaa 23
<210> 890
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 890
uaauagaauu cuuucuaauu ucuucuuaaa c 31
<210> 891
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 891
aguuucguuu uauccaaguc ucg 23
<210> 892
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 892
uugaaaaaua acuaggucac gagu 24
<210> 893
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 893
ucuauagaaa guuuuuuaaa guu 23
<210> 894
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 894
uacguauguu guuacccuua caguaaa 27
<210> 895
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 895
uaacaaauau aaauaaaagu aaa 23
<210> 896
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 896
guuguauuuu uuaguuggua uaa 23
<210> 897
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 897
aggagaaaag aaaaggaaag aggaagaaa 29
<210> 898
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 898
gucuuuucgu cauacucuuc cu 22
<210> 899
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 899
aacggacccc uuuccuccgu ca 22
<210> 900
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 900
agaaaagaaa aggaaagagg aagaaa 26
<210> 901
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 901
agaaaagaaa aggaaagagg aagaaa 26
<210> 902
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 902
caggagaaaa gaaaaggaaa gaggaagaaa 30
<210> 903
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 903
gaaaagaaaa ggaaagagga ag 22
<210> 904
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 904
gagaaaagaa aaggaaagag gaagaa 26
<210> 905
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 905
aauuauucuu augucuaaau aa 22
<210> 906
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 906
agagacucaa ucuuuuacuc uuuca 25
<210> 907
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 907
gaaacguaau uuuuuacaca aacu 24
<210> 908
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 908
aaaauauaca gaucuuuuga aucugugaua u 31
<210> 909
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 909
gauguccuac aucuaaaacu uuuau 25
<210> 910
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 910
agaaacauaa gaccgaaagg aagaaaccaa c 31
<210> 911
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 911
ucuucugugu uuuuuuacac aauuguguuu ug 32
<210> 912
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 912
agucacaaaa gacugagguu ucaa 24
<210> 913
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 913
augguucuuu uacuucuucc gagaagacu 29
<210> 914
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 914
aaaugaacga auacauugga auaaaa 26
<210> 915
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 915
aaagagauaa aagagaacaa aauuug 26
<210> 916
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 916
uucuacugau agauuuuaca gucc 24
<210> 917
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 917
uaagugacgg aagaagggag agu 23
<210> 918
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 918
gacagacgau uggucauacu ugu 23
<210> 919
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 919
ucuuucaaga uaguuctttt ttt 23
<210> 920
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 920
aaaguuuaag gaagagucuu aag 23
<210> 921
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 921
uaaaacaugu cuuccaaaag uauu 24
<210> 922
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 922
uaacuaaucu uuaaguugaa ccuuuuuagu uac 33
<210> 923
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 923
ccuacagaaa cagaaagaaa aagaaac 27
<210> 924
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 924
ugugguuucc cuuugaguga cugucuuuug 30
<210> 925
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 925
cugugucuac uucuuugaag gaaa 24
<210> 926
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 926
auguuggguu cucucgaauu ug 22
<210> 927
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 927
uuucuuacuu cauuuccagu cgu 23
<210> 928
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 928
cacgauaacu agucugauua au 22
<210> 929
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 929
cgaccugaca ccacugucgg ag 22
<210> 930
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 930
guuggagacg uguuuuacuc ga 22
<210> 931
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 931
uguuaccucg uacguuccuu cgu 23
<210> 932
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 932
aucguccauc auagguucug ucucug 26
<210> 933
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 933
uuuuacgacu ccuauacccg uu 22
<210> 934
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 934
guuauugguu ucucuuuuuu cuu 23
<210> 935
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 935
uuaguaccuu caacaaaagg ggu 23
<210> 936
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 936
uucguugguc cucuaaccaa gu 22
<210> 937
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 937
uacguugacu cuagucucgu ag 22
<210> 938
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 938
ggucuccugu ucucgagaac aa 22
<210> 939
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 939
cuccugcucu acccaccuag uucu 24
<210> 940
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 940
cuccugcucu acccaccuag uucuccag 28
<210> 941
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 941
aaccgaguaa gagacaaaaa aaacaaaaaa aa 32
<210> 942
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 942
cuccugcucu acccaccuag uucuccag 28
<210> 943
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 943
gaguaagaga caaaaaaaac aaaaaaaa 28
<210> 944
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 944
gaaauaagau uuuauaaaaa uuua 24
<210> 945
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 945
uacucggguu cugaagaaaa cua 23
<210> 946
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 946
uucuuugaca cuaaaaauua ugaau 25
<210> 947
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 947
uucuuacuau uucguuucuu uu 22
<210> 948
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 948
augaaaauuu cuacguacga aaguaa 26
<210> 949
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 949
aaauuuuuua cuauucuuau uu 22
<210> 950
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 950
ucuuacuauu ucguuucuuu uacauc 26
<210> 951
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 951
augacuagag guugagucuu cu 22
<210> 952
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 952
uuuuaaacuu ucuuacuauu ucguuu 26
<210> 953
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 953
uuuuuacuua cuuuuauacg uaagagaagu uuu 33
<210> 954
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 954
uuucguucuu uuuacuuacu uuu 23
<210> 955
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 955
guucuuuuua cuuacuuuua ua 22
<210> 956
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 956
uccucuuuag uuuuguuuug guau 24
<210> 957
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 957
cguaaguuau uuauguacga c 21
<210> 958
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 958
uacauucuug acauuuauau u 21
<210> 959
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 959
uuuuguuuug guauuuucau c 21
<210> 960
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 960
uuuccucuuu aguuuuguuu ugguauuuu 29
<210> 961
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 961
aucccucgag gggugagggc aaaacacug 29
<210> 962
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 962
auauaguuuu cuuuuacuuu aguu 24
<210> 963
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 963
cuaauuuaaa uauaguuuuc uuuuacuu 28
<210> 964
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 964
auauaguuuu cuuuuacuuu aguuau 26
<210> 965
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 965
uuucuuuuac uuuaguuauc aacuccu 27
<210> 966
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 966
auauaguuuu cuuuuacuuu aguuauc 27
<210> 967
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 967
uacugguuua cauaucuaac ucu 23
<210> 968
<211> 34
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 968
auauaguuuu cuuuuacuuu aguuaucaac uccu 34
<210> 969
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 969
auauaguuuu cuuuuacuuu aguuau 26
<210> 970
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 970
aacuuuauuc uucuaaucua uaaaaauuaa 30
<210> 971
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 971
acuauaguaa aaguuaaugu au 22
<210> 972
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 972
uucuuuuucu ucuaucguuc uu 22
<210> 973
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 973
ucgauuucaa accauccuuu uguu 24
<210> 974
<211> 31
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 974
uuuaguucau uuuauuguua uuuacuguau g 31
<210> 975
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 975
guaauuuaaa uauguuuguu uguguuu 27
<210> 976
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 976
ucgauuucaa accauccuuu uguu 24
<210> 977
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 977
cuuuauaugg uauauuuaua cuaca 25
<210> 978
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 978
uuuauucuag ucuuaaaaua aau 23
<210> 979
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 979
ucuuaauaua auuaugucau au 22
<210> 980
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 980
ucguaauuuu guaaucuuua uaauuuauuc 30
<210> 981
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 981
ucuuaauaua auuaugucau auauca 26
<210> 982
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 982
cuucuuaaua aguguaauua uu 22
<210> 983
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 983
cuucuuguuu gauaauuauu aa 22
<210> 984
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 984
auucuagucu uaaaauaaau aaugau 26
<210> 985
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 985
auuugguuug uaaaaaggaa ua 22
<210> 986
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 986
uaaaauuuug ugaauuuuua aa 22
<210> 987
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 987
guuauaaaga cgacaaguua aguuacc 27
<210> 988
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 988
aaaaaaccca aaacaaacac aacuaugaaa cuc 33
<210> 989
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 989
cguuuaaaua gaauuuaagu ucauguau 28
<210> 990
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 990
auugucugaa ccuuuuuaug uuaa 24
<210> 991
<211> 37
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 991
uaauggaagu uuuuagaucu ugaaauaauu aagaguc 37
<210> 992
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 992
uuuuaauuuu uguuuuuacu uucc 24
<210> 993
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 993
gaauaaaaua cagaagaaac aacaaaaa 28
<210> 994
<211> 33
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 994
uaauaauugu ugaauaaaaa uaaauuagaa aau 33
<210> 995
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 995
uauuucuucu uauaauugua acuguaau 28
<210> 996
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 996
aauacuuaca aaauaguacu aauuucua 28
<210> 997
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 997
gggucguguc ucuacaguaa cu 22
<210> 998
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 998
ucacucuuua cuacuacaac uagucu 26
<210> 999
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 999
aagauuccuu ucguuggucu uc 22
<210> 1000
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1000
acucguucuu cuuuaggaug ua 22
<210> 1001
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1001
ccuuacucuu cuuucgauuu aa 22
<210> 1002
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1002
aaucuuuaca gaauucguaa cg 22
<210> 1003
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1003
guccuguaac uuuuacuucu cuuc 24
<210> 1004
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1004
uucucuuucu ggacugguuu cu 22
<210> 1005
<211> 28
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1005
ugauucagua uauuuuuaug uucuuuuu 28
<210> 1006
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1006
uuguuaaacu caacuaucug uuacuua 27
<210> 1007
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1007
uaguacaaag uaugaagauc gguaac 26
<210> 1008
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1008
cuuuguauga uucuuguguc cuu 23
<210> 1009
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1009
aaagugguaa uggaagagaa gg 22
<210> 1010
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1010
uccuucguuu uaauuugucu cuucuuu 27
<210> 1011
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1011
accuuuuacu uucuugaaac cu 22
<210> 1012
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1012
uuuuguugug aacccauuua gucugu 26
<210> 1013
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1013
cgacgaccug ucagucacca aa 22
<210> 1014
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1014
ccuaguucuu ucuucucaag agacucu 27
<210> 1015
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1015
ccccucugug uguuuaaguc ug 22
<210> 1016
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1016
ugguuuacuu uugggucgag uguucucagu 30
<210> 1017
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1017
uuuacucuua caccuuuggu ac 22
<210> 1018
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1018
ucuuuauucc ucucaaaccg cg 22
<210> 1019
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1019
ucuucucauc ugccuuucac cu 22
<210> 1020
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1020
cuguaagaaa ccgaccuuuc ucggauu 27
<210> 1021
<211> 32
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1021
cuucucucgu cccguucuua guuuugaucc ga 32
<210> 1022
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1022
ucccguucga aaggguuuac ag 22
<210> 1023
<211> 34
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1023
ccuguacuaa ggucucuccu uacuuguucc uguu 34
<210> 1024
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1024
ccuuuaacac uuuuaaguua cc 22
<210> 1025
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1025
cucagaugua agagucaaaa cag 23
<210> 1026
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1026
cucugucugu cauuuccuuu ua 22
<210> 1027
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1027
acuucuuuuu gauuucuuuu uu 22
<210> 1028
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1028
ggucugucgu cugaccuucc gu 22
<210> 1029
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1029
uuguccuuua guauaacuua aaca 24
<210> 1030
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1030
ucauacguac cuuucuaaaa gaauuac 27
<210> 1031
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1031
gucucaaacu uaaaauacua guc 23
<210> 1032
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1032
acucccauug uaaauuaaaa ccc 23
<210> 1033
<211> 27
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1033
aaaaaagaaa aacucuuucc cgaagua 27
<210> 1034
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1034
ucuuuuguug uccacaacua cuc 23
<210> 1035
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1035
aaaaaagaaa aacucuuucc cga 23
<210> 1036
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1036
uuuacuuucu aaaggucuuu aac 23
<210> 1037
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1037
uguugucuau guuguuuacg accacucuua 30
<210> 1038
<211> 30
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1038
uguugucuau guuguuuacg accacucuua 30
<210> 1039
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1039
uacucucuag aacccccacc cug 23
<210> 1040
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1040
gguuacauaa auauguaaau guucau 26
<210> 1041
<211> 29
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1041
uucaaguuac ucuuucucuu aucuauacc 29
<210> 1042
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1042
augaauguac gguuuagagu u 21
<210> 1043
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1043
ucaaguuacu cuuucucuua u 21
<210> 1044
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1044
auguaugaua auuacacuaa au 22
<210> 1045
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1045
aaaacaggaa gguuaacaca ac 22
<210> 1046
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1046
cuucgucucu cuuucaucuc uuc 23
<210> 1047
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1047
aguuuuccuc ucuugucuac gacc 24
<210> 1048
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1048
agggaccuac cguucgucuu cgu 23
<210> 1049
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1049
guccuguaac uuuuacuucu cuuc 24
<210> 1050
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1050
uuguucucgu ccggucacac cacc 24
<210> 1051
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1051
aacuccuuuu cccuugggac augu 24
<210> 1052
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1052
gguccgugac ccuucaguca ccgu 24
<210> 1053
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1053
uuaauccuca cuauggaagu gauu 24
<210> 1054
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1054
acucuuuuuc cggugacagg aaau 24
<210> 1055
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1055
uguuuaaccu cuuuaucacu uuu 23
<210> 1056
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1056
auaaucuuua uuguggauac u 21
<210> 1057
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1057
uuuccuucuu uaacuuuggg ucu 23
<210> 1058
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1058
cuacaguagu ucuuacgucu acg 23
<210> 1059
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1059
uguuuucuac gucuuucucc guuc 24
<210> 1060
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1060
uuacaauaac ucauauaucu cucu 24
<210> 1061
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1061
guaaacuacu agaccguaag guuga 25
<210> 1062
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1062
cuucccuccg acuaggucuu guca 24
<210> 1063
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1063
ccguguugac cucaccucag acga 24
<210> 1064
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1064
guuuucuuuu cuuucuucuc gag 23
<210> 1065
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1065
agguuuaacg aaguuuacuu uu 22
<210> 1066
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1066
uuaacauguu uuugggacua ug 22
<210> 1067
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1067
uacuccuuac cucccuuauc ga 22
<210> 1068
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1068
uaacgaggaa acgaccuacc ua 22
<210> 1069
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1069
aagguuagac uuacuacguu gu 22
<210> 1070
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1070
auuuucgacg uaguuaucca ca 22
<210> 1071
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1071
cccucuaacu agguuuuguc gu 22
<210> 1072
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1072
ucccccuucg ggucuaggac cu 22
<210> 1073
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1073
acggugucuc cucugugugu uu 22
<210> 1074
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1074
cucuuuccuu ucaccuguug u 21
<210> 1075
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1075
guauuguugu uguuauuauu gacuu 25
<210> 1076
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1076
uccuucccuu uuauguuuuu ua 22
<210> 1077
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1077
cuccuuuacu cuucuuccga u 21
<210> 1078
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1078
gaccucgacg accucgucgu c 21
<210> 1079
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1079
agaguuugaa cgucaaccag 20
<210> 1080
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1080
aacugauacc cucacuacaa a 21
<210> 1081
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1081
ucaaacuuaa guaacgacuu c 21
<210> 1082
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1082
cuuuuuguuc uaaagagggu cac 23
<210> 1083
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1083
ugucccacua ccacaggggg 20
<210> 1084
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1084
uuuaccuggu guuugugucu uug 23
<210> 1085
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1085
uacagaagaa guuagugaag uug 23
<210> 1086
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1086
augacgauuc cuucguguuc uac 23
<210> 1087
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1087
uuuuuaacuu ugcuuguuua ag 22
<210> 1088
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1088
uuauuuaugu uguaauggga aa 22
<210> 1089
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1089
uucguucuaa uuuuucucuc cu 22
<210> 1090
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1090
aaucucguag acaaccuucu ua 22
<210> 1091
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1091
uugucuccga cuuguucucc u 21
<210> 1092
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1092
acgucuuccu uguccuugcc g 21
<210> 1093
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1093
uaacauaccu guguuaaucu uug 23
<210> 1094
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1094
uacucuuugc acggacucuu ugu 23
<210> 1095
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1095
acaaaagaag acagacuucu 20
<210> 1096
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1096
guauauuaau cguaguguua 20
<210> 1097
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1097
uguuuagucg ucaaacuuga cuau 24
<210> 1098
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1098
cuuucuccau uuaauuuuuc 20
<210> 1099
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1099
uucaucgucc gagugagacg 20
<210> 1100
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1100
ucuuccucuc uuccuuuuac c 21
<210> 1101
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1101
uguuuaugga cgucuuuacg 20
<210> 1102
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1102
uuacuuaguu guucuuucuu uu 22
<210> 1103
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1103
uuacuuaguu guucuuucuu 20
<210> 1104
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1104
cucuuacuuc ucuuuugagg 20
<210> 1105
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1105
uaagucacuu uaaccuuuua 20
<210> 1106
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1106
ucuuuaugug guucuggugu au 22
<210> 1107
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1107
gaacuugaau cuucgucuau a 21
<210> 1108
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1108
uguuacgaua guuaacauua g 21
<210> 1109
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1109
uguuacgaua guuaacauua 20
<210> 1110
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1110
cuugaagucc uguaucuuuu a 21
<210> 1111
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1111
cggaaggaaa ggucuuacac 20
<210> 1112
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1112
cuauacugaa acuuucccuc 20
<210> 1113
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1113
uccccaaccu uaccgacguc 20
<210> 1114
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1114
gucucaucuu acguuaagag gagu 24
<210> 1115
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1115
aaggacgaaa ugguauuacu gacu 24
<210> 1116
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1116
aaaguauuac agucguuuau acgu 24
<210> 1117
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1117
ccagauguuu uguaugaaac ucuu 24
<210> 1118
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1118
guuuuaaucu cucugucuuu uaucu 25
<210> 1119
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1119
cuucguuuug acaaacacga 20
<210> 1120
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1120
aacaaaaaua caccucgauu agu 23
<210> 1121
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1121
guguuuccug uuauccuuuc uuu 23
<210> 1122
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1122
auuucuuuaa cuuagucauu uauu 24
<210> 1123
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1123
ucacucugug ucccuugucu cuuu 24
<210> 1124
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1124
guauacuuuc uuacacguug uag 23
<210> 1125
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1125
aaguuacuua guuguuuuuu cuuu 24
<210> 1126
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1126
gucgucuauu uucuuauuac cuuuac 26
<210> 1127
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1127
ucaacuauua uuguugacca gacca 25
<210> 1128
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1128
ucuucuucuu uuucuccuga uaaa 24
<210> 1129
<211> 26
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1129
gaagggucaa aaccucacag acccua 26
<210> 1130
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1130
uuuaaauuua uucuuuuacc uucua 25
<210> 1131
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1131
uuagauuacc cuuaaauuau cgag 24
<210> 1132
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1132
uacgucuuga aagaaaaacu gag 23
<210> 1133
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1133
uguaagaaaa guacaccccg uauu 24
<210> 1134
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1134
gaucaguccg auccgucuac ca 22
<210> 1135
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1135
guuucgucuu acgucaagag aa 22
<210> 1136
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1136
acgugguuaa uuuuaugucu aua 23
<210> 1137
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1137
ucucauucuc uguuguacug gu 22
<210> 1138
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1138
cccuuaaccc uguuaccacu ac 22
<210> 1139
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1139
uuacggaaca aagaugauua ug 22
<210> 1140
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1140
auucuccuag uccuuacucu ua 22
<210> 1141
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1141
uagaguaaau uccuuacugu gu 22
<210> 1142
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1142
ucuguuacga uuccuuuauc cc 22
<210> 1143
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1143
ucuguuacga uuccuuuauc cc 22
<210> 1144
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1144
aaccagacuc cuuacacgga cga 23
<210> 1145
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1145
uaguuacuug uuucuccuuu au 22
<210> 1146
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1146
gucucucucc guuuaauuuu uc 22
<210> 1147
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1147
guguuuaacu ucuacugucu cu 22
<210> 1148
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1148
uuuguucuuc acgaauacuc uc 22
<210> 1149
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1149
aaaaaaaguu uacguagaua guu 23
<210> 1150
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1150
gucuuuaagc uucuuuauuu uac 23
<210> 1151
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1151
gucggauuag ucugguuuac uu 22
<210> 1152
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1152
ccugccuaau ucuuucuucu ca 22
<210> 1153
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1153
uuucguuacu uucucauacc ccuc 24
<210> 1154
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1154
ugucuaaacu uuauuaacuu cc 22
<210> 1155
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1155
acguacacau uuaccgagaa c 21
<210> 1156
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1156
gaaaaggacu uucacggucg u 21
<210> 1157
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1157
uucuguucuu uaccggucau cc 22
<210> 1158
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1158
gacguaaacu ucuaaauucu aac 23
<210> 1159
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1159
gguaauaggu uuccagaugu uu 22
<210> 1160
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1160
acucugaagg uucuaguucu ac 22
<210> 1161
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1161
cguccucacc uaucuaagau gu 22
<210> 1162
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1162
uuucguuuaa caucuuuucu aa 22
<210> 1163
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1163
acgucccuuc uugugucuag ag 22
<210> 1164
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1164
aguuuacgua cuucuguaag aa 22
<210> 1165
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1165
ucuucaauau uccuacuacc u 21
<210> 1166
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1166
gacgggguag ccacuucgag g 21
<210> 1167
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1167
uuauggucgg aagguaaagu cuua 24
<210> 1168
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1168
uuacuuaggu uuaguuuccu 20
<210> 1169
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1169
uacggaacaa agaugauuau g 21
<210> 1170
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1170
acucaacggu aagugguaac u 21
<210> 1171
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1171
uauguaacuu caaaauguaa a 21
<210> 1172
<211> 24
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1172
cacacuaccc uuaccaaccu caua 24
<210> 1173
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1173
uauacguguu ugucuuacac a 21
<210> 1174
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1174
accuaaacaa cgguuaaagu 20
<210> 1175
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1175
uaauauuuuc cuuccagagu 20
<210> 1176
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1176
uaauauuuuc cuuccagagu 20
<210> 1177
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1177
auauauuuau cuuguccuug ua 22
<210> 1178
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1178
uguuauuuuu caaccucuuu gu 22
<210> 1179
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1179
uuucgguacc uuguuuaccg ac 22
<210> 1180
<211> 25
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1180
ccagauguuu uguaugaaac ucuuu 25
<210> 1181
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1181
uuaucaaaug aacuuauuau gu 22
<210> 1182
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1182
aaguucuacc ucuuucccuu cu 22
<210> 1183
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1183
uuuucuuuau gugguuuugu ca 22
<210> 1184
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1184
uuggauuuaa agagggucua aa 22
<210> 1185
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1185
uguuggauga aagagucaug ucu 23
<210> 1186
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1186
uuuaaguuug uuccucuagu aa 22
<210> 1187
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1187
accaguccaa uaagaccgua aa 22
<210> 1188
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1188
guuggaccuu ggaccuugga 20
<210> 1189
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1189
ggucgugacu cucccacuga ca 22
<210> 1190
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1190
cuuuaguugg acuuaccaaa 20
<210> 1191
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1191
aauaguuuau gaacgauaua ug 22
<210> 1192
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1192
gaaaagaauu uuuaaggucg cg 22
<210> 1193
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1193
ucucuuccua uaagagacca g 21
<210> 1194
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1194
ccccucugug uguuuaaguc ug 22
<210> 1195
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1195
acuaauaacg acgaucuuug uau 23
<210> 1196
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1196
acuaauaacg acgaucuuug ua 22
<210> 1197
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1197
accucuuucg guuguucuau uuu 23
<210> 1198
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1198
uguuucuugu acuuuuuuug uuc 23
<210> 1199
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1199
ucccguucga aaggguuuac aga 23
<210> 1200
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1200
ucccguucga aaggguuuac ag 22
<210> 1201
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1201
gguuuugaug uaugaccacc cu 22
<210> 1202
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1202
uccguuucac cacacacaca cg 22
<210> 1203
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1203
aguuucucuu ucuguacugg u 21
<210> 1204
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1204
ugaaacauua ggguacuuag g 21
<210> 1205
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1205
aaaguccguc uuacuuacgu c 21
<210> 1206
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1206
cuuugugucc cuugucucuu u 21
<210> 1207
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1207
uuccuucuag aguaaacucc u 21
<210> 1208
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1208
cuaucauuca ccuucucuac uu 22
<210> 1209
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1209
guauacuuuc uuacacguug ua 22
<210> 1210
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1210
uauuaugauc aucauuguca uu 22
<210> 1211
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1211
aacugacuuc uaggucuacu u 21
<210> 1212
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1212
uuuuuacuac ugguuaagag u 21
<210> 1213
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1213
auaccuuaag agagaaugac u 21
<210> 1214
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1214
uuuuuuguuu cuaacucauu cu 22
<210> 1215
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1215
uucguugguc cucuaaccaa gu 22
<210> 1216
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1216
ggucuccugu ucucgagaac aa 22
<210> 1217
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1217
cuuucuugua agaaaaguac ac 22
<210> 1218
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1218
gacauuacuc uuacccucug ga 22
<210> 1219
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1219
ccuuuaacac uuuuaaguua cc 22
<210> 1220
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1220
aaaacgaaac acaacaaaac gac 23
<210> 1221
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1221
uccugaagcu cuuuauacaa cu 22
<210> 1222
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1222
uuuguuguau uguuguuguu auu 23
<210> 1223
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1223
uuuuacgacu ccuauacccg uu 22
<210> 1224
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1224
aaagugguaa uggaagagaa gg 22
<210> 1225
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1225
agaauaaaga agucucuguu ac 22
<210> 1226
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1226
ucucuuuuau gaacuuuuaa cac 23
<210> 1227
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1227
ugucuuuaca gugacucucc uc 22
<210> 1228
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1228
uuucccccau cccuguuacc ac 22
<210> 1229
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1229
cugaugucua uauguauauc ua 22
<210> 1230
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1230
cuuuuuccuc ucacucucug uu 22
<210> 1231
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1231
aucuauauuu acacuuucua au 22
<210> 1232
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1232
agucugucga cgggucuccc gu 22
<210> 1233
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1233
ugaaugguca gaguagaaga u 21
<210> 1234
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1234
aaaagauagg gagucuuuua gg 22
<210> 1235
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1235
gaaacuagag cccgaacucu 20
<210> 1236
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1236
agagagacgg aacaucaacc 20
<210> 1237
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1237
auauugaaua augaagucuu 20
<210> 1238
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1238
ucuuuaguau aguuuaggaa 20
<210> 1239
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1239
aagucugucu agucuggagu 20
<210> 1240
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1240
uuauaggucu uaccaaagac 20
<210> 1241
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1241
uucaguugua cuuuuuuugu c 21
<210> 1242
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1242
acuuuuuuug uucuagaauu 20
<210> 1243
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1243
ccccccaaga aaaacuuuuu 20
<210> 1244
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1244
cucuaccggu uccacccucu 20
<210> 1245
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1245
aaaaaugguu aucaucuccc 20
<210> 1246
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1246
cacgaggagu acuuuacaga ca 22
<210> 1247
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1247
augguggaau uuauagucuc 20
<210> 1248
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1248
gagucgguau uuuuacuugc 20
<210> 1249
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1249
uaacgucuuu caaagagguu uu 22
<210> 1250
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1250
ucugaccugg ucgauaccuu ag 22
<210> 1251
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1251
uacauuagug gaauauguac uug 23
<210> 1252
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1252
ccuuccugaa ccauuucaag 20
<210> 1253
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1253
uuuaggacuc cgugaaguug ua 22
<210> 1254
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1254
cagacaguag agugaccuag 20
<210> 1255
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1255
acccguguca acagugacga 20
<210> 1256
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1256
uuuguaacgu cuguccuauc 20
<210> 1257
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1257
acauuaagau cggacucaga 20
<210> 1258
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1258
gguccuuuca gaagucuccu a 21
<210> 1259
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1259
auuuucuaga aaagaacaga 20
<210> 1260
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1260
ucuguuuauu ccaguccucu 20
<210> 1261
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1261
ucuguugugg gugaggaaga 20
<210> 1262
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1262
auccaaguuc agacggucua ugu 23
<210> 1263
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1263
gaauggucag aguagaagau g 21
<210> 1264
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1264
ccggaacgag aagucucucc 20
<210> 1265
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1265
guacgucgau cuugguacug 20
<210> 1266
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1266
ccccuucuuu ucaccauccg u 21
<210> 1267
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1267
uguccuaucu cgucuaaaaa 20
<210> 1268
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1268
aacuuuuacu uggaacuacu 20
<210> 1269
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1269
guacucguuc uagaaacagu u 21
<210> 1270
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1270
agaacacugu aaaaaugguu a 21
<210> 1271
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1271
guccuugugu ucuugguuuc 20
<210> 1272
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1272
aaguguaauu uuuucacuau 20
<210> 1273
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1273
gacaaccuua ccgguccuac 20
<210> 1274
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1274
uuccaccucu ugagucucaa a 21
<210> 1275
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1275
cguaaaccuu ccauagaacg 20
<210> 1276
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1276
gagauaaaga acgugaacac 20
<210> 1277
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1277
uucuucucug guacacauca aua 23
<210> 1278
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1278
uauuacguaa accuuccaua 20
<210> 1279
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1279
gauacuucag uaguuuuaua 20
<210> 1280
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1280
aagaguaaaa acaacaaaua aa 22
<210> 1281
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1281
uauugucugg auauugaaua 20
<210> 1282
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1282
ucucucugug uuccgauucu 20
<210> 1283
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1283
aaucaggucu cucgucuuuu 20
<210> 1284
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1284
gugacggagg aagucguuag u 21
<210> 1285
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1285
auacuucagu aguuuuauaa 20
<210> 1286
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1286
guaauuuuuu cacuaucuau 20
<210> 1287
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1287
ucucucguag guuucccuca c 21
<210> 1288
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1288
uuuuuuacau gguccacacu 20
<210> 1289
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1289
uuguacucgu ucuagaaaca 20
<210> 1290
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1290
uuaguguaag aaaguggucu u 21
<210> 1291
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1291
ggagugagaa uaaaguaggu 20
<210> 1292
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1292
guaagugaaa cauccuacga 20
<210> 1293
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1293
uagucuuucc gaaauauacu g 21
<210> 1294
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1294
acauaaauau uuucuguucc a 21
<210> 1295
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1295
gaguaaaaac aacaaauaaa 20
<210> 1296
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1296
acgguucgaa cacaaguugu 20
<210> 1297
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1297
acccgagacu guccuccgua c 21
<210> 1298
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1298
uucaauuaau ggaaauguaa 20
<210> 1299
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1299
augauacuac auagauagau 20
<210> 1300
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1300
uccucccaua agaagacaua 20
<210> 1301
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1301
cuugggucuc cuugggggug 20
<210> 1302
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1302
gugacggagg aagucguuag u 21
<210> 1303
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1303
ucucgaguuc uuccucuguu 20
<210> 1304
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1304
uucuccccga ggagauacuu 20
<210> 1305
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1305
agaugacgaa auccacugca 20
<210> 1306
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1306
ucuacccacc uaguucucca 20
<210> 1307
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1307
uugccacugc uccgacuccu 20
<210> 1308
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1308
gucuccuaca uaaaagacag 20
<210> 1309
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1309
guguagguga cggaggaagu 20
<210> 1310
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1310
ucccuacaga acacuguaaa aa 22
<210> 1311
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1311
gaagucuuuc guucaguaag au 22
<210> 1312
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1312
auguagaguc gguauuuuua c 21
<210> 1313
<211> 22
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1313
aaugacucac guccccggga cu 22
<210> 1314
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1314
aguugaaagg guugggaggu 20
<210> 1315
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1315
gucucccugu cccucccucc a 21
<210> 1316
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1316
ucagucuuga accuuacucu a 21
<210> 1317
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1317
aguuucuaau cucaguuguc u 21
<210> 1318
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1318
guacuugacc cauauguuca a 21
<210> 1319
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1319
gacuacugua cgaccucuuc u 21
<210> 1320
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1320
accagugcac aaguuagagu a 21
<210> 1321
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1321
aauacuucug acaaguccug a 21
<210> 1322
<211> 23
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1322
gaccaccucu auuuugcaug acu 23
<210> 1323
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1323
aacuaacaaa aagaguaaaa 20
<210> 1324
<211> 21
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1324
accaaagacc ccgacacgga g 21
<210> 1325
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1325
cucggucccg uccucugucg 20
<210> 1326
<211> 20
<212> DNA/RNA
<213> 人工序列(Artificial Sequence)
<400> 1326
cccaagaaaa acuuuuuuuu 20
Claims (6)
1.一种RNA病毒的靶点序列，其特征在于，所述RNA病毒为新型冠状病毒；所述新型冠状病毒的靶点序列包括SEQ ID NO.1～SEQ ID NO.6。
2.一种用于构建RNA病毒的靶点序列的引物组合物，其特征在于，靶点序列SEQ IDNO.1的引物为SEQ ID NO.616～SEQ ID NO.619；和/或，靶点序列SEQ ID NO.2的引物为SEQID NO.620～SEQ ID NO.623；和/或，靶点序列SEQ ID NO.3的引物为SEQ ID NO.624～SEQID NO.627；和/或，靶点序列SEQ ID NO.4的引物为SEQ ID NO.628～SEQ ID NO.631；和/或，靶点序列SEQ ID NO.5的引物为SEQ ID NO.632～SEQ ID NO.635。
3.一种与权利要求1所述的RNA病毒的靶点序列相关的生物材料，其特征在于，所述生物材料选自选自下述A)～B)中的一种：
A)与权利要求1所述的RNA病毒的靶点序列互补配对的DNA和/或RNA分子；
B)含有权利要求1所述的RNA病毒的靶点序列或A)中所述DNA分子的表达盒、重组载体、重组微生物、重组细胞系。
4.根据权利要求3所述的生物材料，其特征在于，所述生物材料为重组载体，其构建步骤包括：1)设计引物，PCR扩增所述RNA病毒的靶点序列；2)将扩增的序列片段和表达载体酶切，连接目的序列片段和表达载体；3)将连接产物转化大肠杆菌，培养；4)鉴定后提取重组质粒并包装；
其中，所述重组载体上有表达新型冠状病毒SARS-CoV-2的靶点序列。
5.一种如权利要求1所述的RNA病毒的靶点序列在细胞水平上激活相关基因的应用，其特征在于，所述RNA病毒为新型冠状病毒，所述相关基因包括ACE2基因、透明质酸合成酶家族HAS1、HAS2、和HAS3的编码基因和/或片段周围200k以内基因；
其中，SEQ ID NO.3和SEQ ID NO.4所示的靶点序列片段过表达后ACE2基因被激活；
SEQ ID NO.3和SEQ ID NO.4所示的靶点序列片段过表达后HAS1、HAS2和HAS3的编码基因被激活；
SEQ ID NO.4所示的靶点序列片段过表达后FBXO15基因被激活；
SEQ ID NO.3所示的靶点序列片段过表达后MYL9基因被激活；
SEQ ID NO.1所示的靶点序列片段过表达后KALRN基因被激活；
SEQ ID NO.5所示的靶点序列片段过表达后ATP8B1基因被激活；
SEQ ID NO.6所示的靶点序列片段过表达后HAS1、HAS2、HAS3的编码基因、ACE1、C5AR1、EPAS1基因被激活。
6.一种如权利要求1所述的RNA病毒的靶点序列在筛选用于抑制激活靶基因表达的药物中的应用，其特征在于，所述激活靶基因为如权利要求1所述的RNA病毒的靶点序列在细胞水平上激活的相关基因，所述相关基因如权利要求5所述；所述药物为病毒靶点抑制剂antagomir，其将所述RNA病毒的靶点序列的反向互补序列的3’端进行胆固醇修饰和四个硫代骨架修饰，5’端进行两个硫代骨架修饰，全链进行甲氧基修饰，得到相对应的病毒靶点抑制剂antagomir。
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| CN202310056970.2A CN116286886A (zh) | 2020-07-25 | 2020-07-25 | 一种严重急性呼吸综合征冠状病毒的靶点序列及其应用 |
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