CN1118600A - 2-苄基-多环鸟嘌呤衍生物以及制备它们的方法 - Google Patents

2-苄基-多环鸟嘌呤衍生物以及制备它们的方法 Download PDF

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Publication number
CN1118600A
CN1118600A CN94191306A CN94191306A CN1118600A CN 1118600 A CN1118600 A CN 1118600A CN 94191306 A CN94191306 A CN 94191306A CN 94191306 A CN94191306 A CN 94191306A CN 1118600 A CN1118600 A CN 1118600A
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CN
China
Prior art keywords
alkyl
hydrogen
aryl
amino
carbon atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94191306A
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English (en)
Chinese (zh)
Inventor
D·图西安
B·A·麦基特里克
Y·夏
S·查卡拉曼尼尔
D·加卡
D·J·迪本尼迪托
M·库格曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
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Schering Corp
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Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CN1118600A publication Critical patent/CN1118600A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN94191306A 1993-02-26 1994-02-24 2-苄基-多环鸟嘌呤衍生物以及制备它们的方法 Pending CN1118600A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2354993A 1993-02-26 1993-02-26
US2459993A 1993-02-26 1993-02-26
US08/023,549 1993-02-26
US08/024,599 1993-02-26

Publications (1)

Publication Number Publication Date
CN1118600A true CN1118600A (zh) 1996-03-13

Family

ID=26697306

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94191306A Pending CN1118600A (zh) 1993-02-26 1994-02-24 2-苄基-多环鸟嘌呤衍生物以及制备它们的方法

Country Status (14)

Country Link
US (1) US5939419A (enExample)
EP (1) EP0686157A1 (enExample)
JP (1) JPH08507068A (enExample)
KR (1) KR960701058A (enExample)
CN (1) CN1118600A (enExample)
AU (1) AU681875B2 (enExample)
CA (1) CA2156918A1 (enExample)
FI (1) FI953981A7 (enExample)
HU (1) HUT72640A (enExample)
IL (1) IL108754A0 (enExample)
NZ (1) NZ262797A (enExample)
SG (1) SG43809A1 (enExample)
TW (1) TW270118B (enExample)
WO (1) WO1994019351A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1315835C (zh) * 2001-08-28 2007-05-16 先灵公司 多环鸟嘌呤磷酸二酯酶v抑制剂

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CN1315835C (zh) * 2001-08-28 2007-05-16 先灵公司 多环鸟嘌呤磷酸二酯酶v抑制剂

Also Published As

Publication number Publication date
AU6268794A (en) 1994-09-14
SG43809A1 (en) 1997-11-14
US5939419A (en) 1999-08-17
AU681875B2 (en) 1997-09-11
EP0686157A1 (en) 1995-12-13
JPH08507068A (ja) 1996-07-30
HU9502464D0 (en) 1995-10-30
TW270118B (enExample) 1996-02-11
FI953981A0 (fi) 1995-08-24
WO1994019351A1 (en) 1994-09-01
IL108754A0 (en) 1994-06-24
HUT72640A (en) 1996-05-28
FI953981A7 (fi) 1995-08-24
NZ262797A (en) 1997-08-22
CA2156918A1 (en) 1994-09-01
KR960701058A (ko) 1996-02-24

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