CN111686194A - Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof - Google Patents

Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof Download PDF

Info

Publication number
CN111686194A
CN111686194A CN201910381969.0A CN201910381969A CN111686194A CN 111686194 A CN111686194 A CN 111686194A CN 201910381969 A CN201910381969 A CN 201910381969A CN 111686194 A CN111686194 A CN 111686194A
Authority
CN
China
Prior art keywords
parts
chinese herbal
herbal medicine
adjuvant therapy
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910381969.0A
Other languages
Chinese (zh)
Inventor
董扬
许则滩
王超君
段胜常
吕杨眉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yunnan Nabo Biotechnology Co ltd
Original Assignee
Yunnan Nabo Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yunnan Nabo Biotechnology Co ltd filed Critical Yunnan Nabo Biotechnology Co ltd
Priority to CN201910381969.0A priority Critical patent/CN111686194A/en
Publication of CN111686194A publication Critical patent/CN111686194A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Chinese herbal medicine for adjuvant therapy of diabetes and a preparation method thereof, belonging to the field of Chinese herbal medicine preparation. The Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 36-40 parts of pseudo-ginseng stem leaves, 12-16 parts of gardenia fruits, 1-3 parts of wolfberry fruits, 1-3 parts of rhizoma polygonati, 2-4 parts of lotus leaves, 2-4 parts of mulberry leaves, 12-16 parts of kudzu roots and 17-21 parts of tartary buckwheat; the invention utilizes the compatibility of the components of the Chinese herbal medicines to effectively activate the inert insulin, so that the inert insulin recovers the activity and participates in the normal glycometabolism process; the raw materials are rich, and the health-care tea has the effects of tonifying qi, nourishing yin, reducing blood sugar, regulating lipid, reducing blood pressure, and promoting blood circulation to remove blood stasis; compared with other Chinese herbal medicines in the prior art, the Chinese herbal medicine has a simple formula, does not contain rare medicines, has low cost and can greatly reduce the economic burden of patients and families.

Description

Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof
Technical Field
The invention relates to the technical field of Chinese herbal medicine preparation, in particular to a Chinese herbal medicine for adjuvant therapy of diabetes and a preparation method thereof.
Background
Diabetes is a relatively common endocrine-metabolic disease. The disease is mainly caused by insufficient insulin secretion and inappropriately excessive glucagon secretion. The traditional Chinese medicine is called as diabetes, the typical symptoms of polyphagia, polydipsia, diuresis and emaciation of body form are caused by deficiency of yin of patients and weakness of five internal organs, the general symptoms of the diabetes are lumbago, soreness and pain of limbs, feelings of ants, numbness, skin pruritus and hyposexuality, serious patients can be complicated with heart, kidney and retinopathy, and ketoacidosis can be caused to cause coma and death.
At present, western medicine therapy is mostly adopted for treating diabetes, mainly comprising insulin secretion promoters, alpha-glucosidase inhibitors, growth factor antagonists, angiotensin converting enzyme inhibitors and the like, such as insulin, biguanides, sulfonylureas and the like, but the western medicine has certain limitation and larger side effect, has larger damage to liver and kidney after long-term administration, is easy to generate drug resistance, and is difficult to fundamentally treat the diabetes. Therefore, it is the focus of research to find a traditional Chinese medicine for treating diabetes, which has better effect, can be used for a long time and has small side effect.
Disclosure of Invention
The invention aims to solve the problems that Chinese and western medicines in the prior art have certain limitation and large side effect, and the Chinese and western medicines have large damage to the liver and the kidney and are easy to generate drug resistance after being taken for a long time and are difficult to fundamentally treat diabetes, and provides a Chinese herbal medicine for adjuvant therapy of diabetes and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 31-45 parts of pseudo-ginseng stem leaves, 7-21 parts of gardenia fruits, 0.5-4 parts of wolfberry fruits, 0.5-4 parts of rhizoma polygonati, 1-7 parts of lotus leaves, 1-6.5 parts of mulberry leaves, 7-21 parts of kudzu roots and 12-26 parts of tartary buckwheat.
Preferably, the Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 36-40 parts of pseudo-ginseng stem leaves, 12-16 parts of gardenia fruits, 1-3 parts of wolfberry fruits, 1-3 parts of rhizoma polygonati, 2-4 parts of lotus leaves, 2-4 parts of mulberry leaves, 12-16 parts of kudzu roots and 17-21 parts of tartary buckwheat.
Preferably, the Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 38 parts of pseudo-ginseng stem leaves, 14 parts of gardenia fruits, 2 parts of wolfberry fruits, 2 parts of rhizoma polygonati, 3 parts of lotus leaves, 3 parts of mulberry leaves, 14 parts of kudzu roots and 19 parts of tartary buckwheat.
Preferably, the Chinese herbal medicine for adjuvant therapy of diabetes and the preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: weighing the raw materials according to a given proportion, pouring the raw materials into a boiling and extracting pot, and adding purified water with the weight 6-12 times of that of the medicinal materials.
Step two: boiling with strong fire, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid a.
Step three: adding 6-12 times of purified water into the residue, boiling, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid b.
Step four: mixing the liquid medicine a and the liquid medicine b, and filtering the mixture through a 100-mesh stainless steel screen to obtain liquid medicine c.
Step five: concentrating the liquid medicine c in a concentration tank to a relative specific gravity of 1.10-1.30g/ml, and filtering with a 230-mesh stainless steel filter screen to obtain liquid medicine d.
Step six: and adding auxiliary materials into the liquid medicine d, mixing and stirring for 15 minutes to obtain a mixture e.
Step seven: and (3) putting the mixture e into a drying box, setting the temperature to be 50-60 ℃, and keeping the water content to be less than 10% after 12 hours to obtain a mixture f.
Step eight: and (3) placing the mixture f into an ultramicro crusher, and crushing the mixture f into particles g with the particle size of less than 0.1 micrometer.
Step nine: and (3) carrying out microwave irradiation heating on the particles g to promote the oil-containing cells to be fully cracked and reduce the water content to 4-8%.
Step ten: and granulating the irradiated granules g, bagging and sealing to obtain the radiation-resistant granules.
Preferably, purified water with the amount 9 times that of the medicinal materials is added in the first step and the third step.
Preferably, the second step and the third step are boiled for 2 hours by slow fire.
Preferably, the liquid medicine c in the fifth step is concentrated to the relative specific gravity of 1.180-1.200 g/ml.
Preferably, the auxiliary materials in the sixth step are one or more of pectin, EGCG, xylitol and edible essence.
Preferably, in the step eight, the mixture f is micronized to form particles g with a particle size of about 0.01 microns.
Preferably, the water content is reduced to 6% in the ninth step.
Compared with the prior art, the invention provides a Chinese herbal medicine for adjuvant therapy of diabetes and a preparation method thereof, and the Chinese herbal medicine has the following beneficial effects:
1. the Chinese herbal medicine for adjuvant therapy of diabetes has the functions of resisting oxidation and enhancing human immunity by adding tartary buckwheat; the tartary buckwheat can effectively reduce hypertension, hyperlipidemia and hyperglycemia; can remove in vivo waste, improve heart and brain circulation, relieve fatigue, and recover energy; the tartary buckwheat contains a large amount of coarse grain dietary fibers, so that the antioxidation function of the skin can be increased, the skin is healthy and glossy, and the beauty is maintained; the buckwheat flavone contained in the buckwheat can effectively prevent and treat diabetes; the tartary buckwheat contains rare coarse food grain dietary fiber, so that the distribution of gastrointestinal nutrition can be balanced, and constipation can be effectively treated.
2. The Chinese herbal medicine for adjuvant therapy of diabetes is added with auxiliary materials, so that liquid medicine can be easily prepared into decoction, granules, tablets, pills, capsules or dripping pills, and the required preparation types are prepared according to the requirements of users.
3. The Chinese herbal medicine for the adjuvant treatment of diabetes promotes the oil-containing cells to be fully cracked by microwave irradiation heating, so that the water content of the oil-containing cells is reduced to 6%, the medicine property is improved, and the possibility of overdue medicine is reduced.
The invention utilizes the compatibility among each component of Chinese herbal medicine, effectively activates the inert insulin, leads the inert insulin to recover the activity and participate in the normal glycometabolism process; the raw materials are rich, and the health-care tea has the effects of tonifying qi, nourishing yin, reducing blood sugar, regulating lipid, reducing blood pressure, and promoting blood circulation to remove blood stasis; compared with other Chinese herbal medicines in the prior art, the Chinese herbal medicine has a simple formula, does not contain rare medicines, has low cost and can greatly reduce the economic burden of patients and families.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations and positional relationships only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example 1:
the Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 31 parts of pseudo-ginseng stem leaves, 7 parts of gardenia fruits, 0.5 part of wolfberry fruits, 0.5 part of rhizoma polygonati, 1 part of lotus leaves, 1 part of mulberry leaves, 7 parts of kudzu roots and 12 parts of tartary buckwheat.
The Chinese herbal medicine for adjuvant therapy of diabetes and the preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: weighing the raw materials according to the formula in a given proportion, pouring the raw materials into a boiling and extracting pot, and adding 9 times of purified water.
Step two: boiling with strong fire, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid a.
Step three: adding 9 times of purified water into the residue, boiling, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid b.
Step four: mixing the liquid medicine a and the liquid medicine b, and filtering the mixture through a 100-mesh stainless steel screen to obtain liquid medicine c.
Step five: concentrating the liquid medicine c in a concentration tank to a relative specific gravity of 1.180-1.200g/ml, and filtering with a 230-mesh stainless steel filter screen to obtain liquid medicine d.
Step six: and adding one or more of pectin, EGCG, xylitol and edible essence into the liquid medicine d, and mixing and stirring for 15 minutes to obtain a mixture e.
Step seven: and (3) putting the mixture e into a drying box, setting the temperature to be 50-60 ℃, and keeping the water content to be less than 10% after 12 hours to obtain a mixture f.
Step eight: and (3) placing the mixture f into an ultramicro crusher, and crushing the mixture f into particles g with the particle size of less than 0.01 micrometer.
Step nine: and (3) carrying out microwave irradiation heating on the particles g to promote the oil-containing cells to be fully cracked, so that the water content of the oil-containing cells is reduced to 6%.
Step ten: and granulating the irradiated granules g, bagging and sealing to obtain the radiation-resistant granules.
Example 2:
the Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 45 parts of pseudo-ginseng stem leaves, 21 parts of gardenia fruits, 4 parts of wolfberry fruits, 4 parts of rhizoma polygonati, 7 parts of lotus leaves, 6.5 parts of mulberry leaves, 21 parts of kudzu roots and 26 parts of tartary buckwheat.
The Chinese herbal medicine for adjuvant therapy of diabetes and the preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: weighing the raw materials according to the formula in a given proportion, pouring the raw materials into a boiling and extracting pot, and adding 9 times of purified water.
Step two: boiling with strong fire, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid a.
Step three: adding 9 times of purified water into the residue, boiling, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid b.
Step four: mixing the liquid medicine a and the liquid medicine b, and filtering the mixture through a 100-mesh stainless steel screen to obtain liquid medicine c.
Step five: concentrating the liquid medicine c in a concentration tank to a relative specific gravity of 1.180-1.200g/ml, and filtering with a 230-mesh stainless steel filter screen to obtain liquid medicine d.
Step six: and adding one or more of pectin, EGCG, xylitol and edible essence into the liquid medicine d, and mixing and stirring for 15 minutes to obtain a mixture e.
Step seven: and (3) putting the mixture e into a drying box, setting the temperature to be 50-60 ℃, and keeping the water content to be less than 10% after 12 hours to obtain a mixture f.
Step eight: and (3) placing the mixture f into an ultramicro crusher, and crushing the mixture f into particles g with the particle size of less than 0.01 micrometer.
Step nine: and (3) carrying out microwave irradiation heating on the particles g to promote the oil-containing cells to be fully cracked, so that the water content of the oil-containing cells is reduced to 6%.
Step ten: and granulating the irradiated granules g, bagging and sealing to obtain the radiation-resistant granules.
Example 3:
the Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 38 parts of pseudo-ginseng stem leaves, 14 parts of gardenia fruits, 2 parts of wolfberry fruits, 2 parts of rhizoma polygonati, 3 parts of lotus leaves, 3 parts of mulberry leaves, 14 parts of kudzu roots and 19 parts of tartary buckwheat.
The Chinese herbal medicine for adjuvant therapy of diabetes and the preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: weighing the raw materials according to the formula in a given proportion, pouring the raw materials into a boiling and extracting pot, and adding 9 times of purified water.
Step two: boiling with strong fire, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid a.
Step three: adding 9 times of purified water into the residue, boiling, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid b.
Step four: mixing the liquid medicine a and the liquid medicine b, and filtering the mixture through a 100-mesh stainless steel screen to obtain liquid medicine c.
Step five: concentrating the liquid medicine c in a concentration tank to a relative specific gravity of 1.180-1.200g/ml, and filtering with a 230-mesh stainless steel filter screen to obtain liquid medicine d.
Step six: and adding one or more of pectin, EGCG, xylitol and edible essence into the liquid medicine d, and mixing and stirring for 15 minutes to obtain a mixture e.
Step seven: and (3) putting the mixture e into a drying box, setting the temperature to be 50-60 ℃, and keeping the water content to be less than 10% after 12 hours to obtain a mixture f.
Step eight: and (3) placing the mixture f into an ultramicro crusher, and crushing the mixture f into particles g with the particle size of less than 0.01 micrometer.
Step nine: and (3) carrying out microwave irradiation heating on the particles g to promote the oil-containing cells to be fully cracked, so that the water content of the oil-containing cells is reduced to 6%.
Step ten: and granulating the irradiated granules g, bagging and sealing to obtain the radiation-resistant granules.
The stem and leaf of pseudo-ginseng has the effects of reducing blood fat, resisting inflammation and delaying senility. The record of the compendium of materia Medica is Shi Yi: ginseng, radix Ginseng and Notoginseng are the most valuable Chinese herbs, because it tonifies qi the first time and tonifies blood the first time, and its flavor is the same and powerful. "; the gardenia fruits are bitter in taste and cold in nature, and have the effects of purging fire, relieving restlessness, clearing heat, promoting diuresis, cooling blood and detoxifying; the medlar has the effects of regulating blood fat, reducing blood sugar, reducing blood pressure and protecting liver. The compendium of materia Medica records: medlar, sweet in nature and taste, neutral in nature and flavor. It enters liver and kidney meridians. Has the functions of supplementing qi and nourishing yin, nourishing liver and kidney, and benefiting essence and improving eyesight; rhizoma Polygonati is sweet in taste and neutral in nature, and has effects of invigorating spleen, moistening lung, invigorating qi and nourishing yin. The Shenxianziao Jing records the functions of rhizoma polygonati as follows: to strengthen the middle energizer and replenish qi, harmonize the five zang organs and enrich the muscles. "; lotus leaf, bitter and astringent in flavor, is neutral and enters liver, spleen, stomach and heart meridians. Has effects in clearing summer-heat, promoting diuresis, invigorating hair, clearing yang, cooling blood, and stopping bleeding; mulberry leaf, bitter and sweet in taste and cold in nature. Has effects of dispelling pathogenic wind and heat, clearing lung-heat, moistening dryness, suppressing hyperactive liver, improving eyesight, cooling blood, and stopping bleeding. The book Ben Cao fen Jing (the materia Medica of materia Medica): bitter, sweet and cool. Nourish dryness and cool blood, stop bleeding and dispel wind, clear and purge qi heat of shaoyang. "; kudzuvine root, sweet and pungent in flavor, cool in nature. Has the effects of expelling pathogenic factors from muscles, relieving fever, promoting eruption, promoting salivation, quenching thirst, invigorating yang, and relieving diarrhea. The book Jing: diabetes, fever, vomiting, various kinds of arthralgia, yin qi generation and toxin expelling; the tartary buckwheat has the effects of regulating blood sugar and blood fat, protecting the liver, resisting oxidation and resisting tumors. Recorded in compendium of materia medica, tartary buckwheat is bitter in taste and neutral in nature and cold, and can strengthen intestines and stomach, tonify qi, keep spirit, benefit ears and eyes, and refine five internal organs and dregs. Tartary buckwheat is recorded in Qianjin Yao Fang, Chinese medicine dictionary and related documents, and has the effects of soothing the nerves, activating qi and blood, lowering qi, widening the intestines, clearing away heat, swelling and pain, removing stagnation, clearing away the bowels, moistening the intestines, relaxing the bowels, relieving cough, relieving asthma, resisting inflammation, resisting allergy, strengthening the heart, losing weight, beautifying and the like.
In the invention, the Chinese herbal medicine has the functions of resisting oxidation and enhancing human immunity by adding the tartary buckwheat; the tartary buckwheat can effectively reduce hypertension, hyperlipidemia and hyperglycemia; can remove in vivo waste, improve heart and brain circulation, relieve fatigue, and recover energy; the tartary buckwheat contains a large amount of coarse grain dietary fibers, so that the antioxidation function of the skin can be increased, the skin is healthy and glossy, and the beauty is maintained; the buckwheat flavone contained in the buckwheat can effectively prevent and treat diabetes; the tartary buckwheat contains rare coarse food grain dietary fiber, so that the distribution of gastrointestinal nutrition can be balanced, and constipation can be effectively treated; through adding auxiliary materials, the liquid medicine is easily prepared into decoction, granules, tablets, pills, capsules or dripping pills, and the required preparation types are prepared according to the requirements of users; the oil-containing cells are promoted to be fully cracked by microwave irradiation heating, so that the water content of the oil-containing cells is reduced to 6 percent, the drug property is improved, and the possibility of overdue drugs is reduced; the compatibility of the components of the Chinese herbal medicines is utilized to effectively activate the inert insulin, so that the inert insulin recovers the activity and participates in the normal glycometabolism process; the raw materials are rich, and the health-care tea has the effects of tonifying qi, nourishing yin, reducing blood sugar, regulating lipid, reducing blood pressure, and promoting blood circulation to remove blood stasis; compared with other Chinese herbal medicines in the prior art, the Chinese herbal medicine has a simple formula, does not contain rare medicines, has low cost and can greatly reduce the economic burden of patients and families.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (10)

1. The Chinese herbal medicine for adjuvant therapy of diabetes is characterized by comprising the following raw materials in parts by weight: 31-45 parts of pseudo-ginseng stem leaves, 7-21 parts of gardenia fruits, 0.5-4 parts of wolfberry fruits, 0.5-4 parts of rhizoma polygonati, 1-7 parts of lotus leaves, 1-6.5 parts of mulberry leaves, 7-21 parts of kudzu roots and 12-26 parts of tartary buckwheat.
2. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus according to claim 1, is characterized by comprising the following raw materials in parts by weight: 36-40 parts of pseudo-ginseng stem leaves, 12-16 parts of gardenia fruits, 1-3 parts of wolfberry fruits, 1-3 parts of rhizoma polygonati, 2-4 parts of lotus leaves, 2-4 parts of mulberry leaves, 12-16 parts of kudzu roots and 17-21 parts of tartary buckwheat.
3. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus according to claim 1, is characterized by comprising the following raw materials in parts by weight: 38 parts of pseudo-ginseng stem leaves, 14 parts of gardenia fruits, 2 parts of wolfberry fruits, 2 parts of rhizoma polygonati, 3 parts of lotus leaves, 3 parts of mulberry leaves, 14 parts of kudzu roots and 19 parts of tartary buckwheat.
4. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus and the preparation method thereof according to claim 1 are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: weighing the raw materials according to a given proportion, pouring the raw materials into a boiling and extracting pot, and adding purified water with the weight 6-12 times of that of the medicinal materials.
Step two: boiling with strong fire, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid a.
Step three: adding 6-12 times of purified water into the residue, boiling, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid b.
Step four: mixing the liquid medicine a and the liquid medicine b, and filtering the mixture through a 100-mesh stainless steel screen to obtain liquid medicine c.
Step five: concentrating the liquid medicine c in a concentration tank to a relative specific gravity of 1.10-1.30g/ml, and filtering with a 230-mesh stainless steel filter screen to obtain liquid medicine d.
Step six: and adding auxiliary materials into the liquid medicine d, mixing and stirring for 15 minutes to obtain a mixture e.
Step seven: and (3) putting the mixture e into a drying box, setting the temperature to be 50-60 ℃, and keeping the water content to be less than 10% after 12 hours to obtain a mixture f.
Step eight: and (3) placing the mixture f into an ultramicro crusher, and crushing the mixture f into particles g with the particle size of less than 0.1 micrometer.
Step nine: and (3) carrying out microwave irradiation heating on the particles g to promote the oil-containing cells to be fully cracked and reduce the water content to 4-8%.
Step ten: and granulating the irradiated granules g, bagging and sealing to obtain the radiation-resistant granules.
5. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus and the preparation method thereof according to claim 1, characterized in that purified water with 9 times of the amount of the medicinal materials is added in the first step and the third step.
6. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus and the preparation method thereof as claimed in claim 1, wherein the second step and the third step are decocted with slow fire for 2 hours.
7. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus and the preparation method thereof as claimed in claim 1, wherein the Chinese herbal medicine liquid c in the fifth step is concentrated to a relative specific gravity of 1.180-1.200 g/ml.
8. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus and the preparation method thereof as claimed in claim 1, wherein the adjuvant in the sixth step is one or more of pectin, EGCG, xylitol and edible essence.
9. The herb medicine for the adjuvant treatment of diabetes mellitus of claim 1, wherein in step eight the mixture f is micronized to particles g with a particle size of about 0.01 μm.
10. The Chinese herbal medicine for adjuvant therapy of diabetes mellitus and the preparation method thereof as claimed in claim 1, wherein in the ninth step, the water content is reduced to 6%.
CN201910381969.0A 2019-05-09 2019-05-09 Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof Pending CN111686194A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910381969.0A CN111686194A (en) 2019-05-09 2019-05-09 Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910381969.0A CN111686194A (en) 2019-05-09 2019-05-09 Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof

Publications (1)

Publication Number Publication Date
CN111686194A true CN111686194A (en) 2020-09-22

Family

ID=72476018

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910381969.0A Pending CN111686194A (en) 2019-05-09 2019-05-09 Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof

Country Status (1)

Country Link
CN (1) CN111686194A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643641A (en) * 2020-07-08 2020-09-11 上海中医药大学 Food therapy formula for clearing heat, invigorating spleen and tonifying kidney and preparation method and application thereof
CN113197257A (en) * 2021-05-08 2021-08-03 赵之钦 Health tea for type 2 diabetes

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643641A (en) * 2020-07-08 2020-09-11 上海中医药大学 Food therapy formula for clearing heat, invigorating spleen and tonifying kidney and preparation method and application thereof
CN111643641B (en) * 2020-07-08 2022-02-11 上海中医药大学 Food therapy formula for clearing heat, invigorating spleen and tonifying kidney and preparation method and application thereof
CN113197257A (en) * 2021-05-08 2021-08-03 赵之钦 Health tea for type 2 diabetes

Similar Documents

Publication Publication Date Title
CN103656557A (en) Traditional Chinese medicine composition for strengthening brain and soothing nerves and preparation method thereof
CN101518595A (en) Medical composition with functions of lowering lipid, reducing fat and oxidation resistance and preparation method thereof
CN110170009B (en) Traditional Chinese medicine formula for dispelling effects of alcohol and protecting liver, formula extract and preparation method and application thereof
CN105285260A (en) Anti-alcoholism health tea
CN113995788A (en) Composition for protecting liver and preparation process thereof
CN111686194A (en) Chinese herbal medicine for adjuvant therapy of diabetes and preparation method thereof
CN104474472B (en) Buccal lozenge of lectuce tea and its production method with three high drop effect
CN101698026B (en) Method for producing traditional Chinese medicine formula for treating eye disease of amblyopia
CN104922299A (en) Traditional Chinese medicine healthcare oral liquid used for preventing and treating diabetic retinopathy
CN101011562A (en) Novel formulation of shenqiwendan decoction and production method thereof
CN104431195A (en) Heat clearing type herbal tea and preparation method thereof
CN101129638A (en) Health care medicinal liquor
CN106109521A (en) A kind of Radix Notoginseng oral liquid
CN105796753A (en) Hepatoprotection traditional Chinese medicine composition and preparation method thereof
CN115089661A (en) Application of ginseng composition for assisting in regulating endocrine metabolism and resisting and preventing cancer
CN105995711A (en) Fructus phyllanthi compound preparation and preparation method thereof
AU2020101678A4 (en) A health care drink and preparation method thereof
CN111888431A (en) Composition for treating diabetes and preparation method thereof
CN110882362A (en) Traditional Chinese medicine food therapy product for conditioning diabetes and preparation method thereof
CN105168892A (en) Chinese herbal preparation for treating hypoglycemia and preparing method of Chinese herbal preparation
CN103798472A (en) Healthcare tea and healthcare life-maintaining preparation
CN111388604B (en) Traditional Chinese medicine composition for treating migraine and preparation method thereof
CN111686196A (en) Traditional Chinese medicine composition for improving immunity and preparation method thereof
CN107149627A (en) Compound Chinese medicinal preparation and preparation method for treating yin-yang deficiency Anemia disease
CN106954704A (en) A kind of Dealcoholic liver-protecting tea

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination