CN105168892A - Chinese herbal preparation for treating hypoglycemia and preparing method of Chinese herbal preparation - Google Patents
Chinese herbal preparation for treating hypoglycemia and preparing method of Chinese herbal preparation Download PDFInfo
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Abstract
The invention relates to a Chinese herbal preparation for treating hypoglycemia and a preparing method of the Chinese herbal preparation and belongs to the field of traditional Chinese medicine. The Chinese herbal preparation is prepared from angelica sinensis, cordyceps sobolifera, poria with hostwood, limonium sinense, flowers of kudzuvine, rust-colored crotalaria herbs with roots, alectoria asiatica rietz, sarcopyramis nepalensis, pagodatree pod, rorippa indica, whorledleaf solomonseal rhizome, Chinese yam, polygala tenuifolia, Chinese alpine rush, polygala japonica and liquorice. The compatibility of the medicine materials selected for the Chinese herbal preparation are appropriate and conforms to the traditional Chinese medicine and modern medicine theory, the Chinese herbal preparation has the effects of tonifying the heart and the spleen, nourishing the liver, relieving dizziness, supplementing qi to restore yang and inducing resuscitation, and is convenient to use, good in absorbing effect and free of adverse, toxic and side effects, and it is clinically verified that the Chinese herbal preparation has the excellent relieving and treating effect on hypoglycemia and suitable for clinical treatment of hypoglycemia and nursing application and popularization.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and the preparation method that are used for the treatment of hypoglycemia.
Background technology
Hypoglycemia refers to the too low caused syndrome of the blood sugar concentration caused by many reasons.General with plasma glucose concentration <2.8mmol/L, or full blood glucose <2.5mmol/L is hypoglycemia.The diagnostic criteria of child's hypoglycemia is worth low 1.11mmol/L than adult.
Blood glucose is the main energy sources of brain cell.During hypoglycemia, cerebral tissue mainly relies on the glycogenolysis of brain itself and liver deposit to carry out maintenance metabolism, and the glycogen that cerebral tissue itself is laid in is limited, only 800mg/dl, and especially cerebral cortex is only containing 73mg/dl.Therefore hypoglycemia on the impact of body based on nervous system, especially brain and (or) sympathetic nerve.Serious and long-term hypoglycemic episodes can cause nervous system lesion widely.Lacking sugar early stage is cephalemia, multiple hemorrhages point; Later stage causes cerebrocellular edema and hemorrhagic spotty necrosis because Na+, K+ enter cell, the most obvious with places such as cerebral cortex, basal nuclei, Hippocampus; Late period neuronal cell death, disappearance, cerebral tissue soften.Early stage be that cerebral cortex is suppressed, and subcortical center comprises basal nuclei, hypothalamus and centers of autonomic nerve and in succession involves then, finally affects midbrain and medulla oblongata activity.Brain cell is more evolved more responsive to Anoxia.
Hypoglycemic clinical symptoms has:
1. acute hypoglycemia and the short person of the course of disease are sympathetic activation disease group, as fermented, hunger, weakness, perspiration, tachycardia, systolic pressure raise, diastolic pressure reduce, tremble, temporary amaurosis, disturbance of consciousness, even goes into a coma.
2. subacute and slow blood glucose descender is encephalopathy symptom, and form is varied, but the symptom that same patient shows effect often in same type at every turn.Most patient show as cerebral cortex and (or) symptom of cerebellum, as headache, dizziness, anxiety, enrage, drowsiness, attention laxes, disorientation, tremble, epilepsy grand mal or petit mal, personality changes (cry, disturb by making noise, make a noise, scold), singular behavior, ataxia etc., last numb stupor.Long-term severe hypoglycemia can cause permanent brain damage.
Hypoglycemia severe patient needs intravenous injection immediately 50% glucose 40ml, continue and to instil with 5-10% glucose, may be that long-term hypoglycemia or hypoglycemia are with heating person or hypocrine hypoglycemia to supplementary glucose without significant reaction person, therefore more substantial glucose must be supplemented, but troublesome poeration like this, waste time and energy, and Chinese materia medica is as the traditional medicine of China, there is effect strong, instant effect, the advantages such as lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore a kind of Chinese medicine preparation is selected to be used for the treatment of hypoglycemia, for treatment hypoglycemia, there is very important clinical meaning.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and the preparation method that are used for the treatment of hypoglycemia, selected medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, there is invigorating the heart and spleen, nourishing the liver relieve dizziness, high fever, infantile convulsions, epilepsy, etc., supplementing QI to revive YANG, refreshment of having one's ideas straightened out effect, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, have fabulous alleviation and therapeutic effect to treatment hypoglycemia, the clinical treatment and the nursing that are suitable for hypoglycemia are applied.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of Chinese medicine preparation being used for the treatment of hypoglycemia make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Radix Angelicae Sinensis 51 ~ 81 parts of Periostracum cicadaes 48 ~ 78 parts of Poria cum Radix Pinis 46 ~ 76 parts of Herba Limonii Gmelinii 44 ~ 74 parts
Flos puerariae lobatae 41 ~ 71 parts of Herba Crotalariae Ferrugineaes 36 ~ 66 parts of Alectoria asiatica Du Rietzs 33 ~ 63 parts of Herba Sarcopyramis nepalensis 31 ~ 61 parts
The Fructus Sophorae 29 ~ 59 Fen Herba Rorippae 26 ~ 56 parts of Rhizoma Polygonati Verticillatis 24 ~ 54 portions of Rhizoma Dioscoreaes 22 ~ 52 parts
11 ~ 41 parts, Radix Polygalae 21 ~ 51 portions of Herba Poae Sphondylodiss 17 ~ 47 parts of Herba Polygalae Japonicae 16 ~ 46 portions of Radix Glycyrrhizaes.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 74 parts of Periostracum cicadaes 71 parts of Poria cum Radix Pinis 69 parts of Herba Limonii Gmelinii 67 parts
Flos puerariae lobatae 64 parts of Herba Crotalariae Ferrugineaes 59 parts of Alectoria asiatica Du Rietzs 57 parts of Herba Sarcopyramis nepalensis 55 parts
The Fructus Sophorae 53 Fen Herba Rorippae 49 parts of Rhizoma Polygonati Verticillatis 47 portions of Rhizoma Dioscoreaes 45 parts
34 parts, Radix Polygalae 44 portions of Herba Poae Sphondylodiss 40 parts of Herba Polygalae Japonicae 39 portions of Radix Glycyrrhizaes.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 67 parts of Periostracum cicadaes 64 parts of Poria cum Radix Pinis 62 parts of Herba Limonii Gmelinii 60 parts
Flos puerariae lobatae 57 parts of Herba Crotalariae Ferrugineaes 52 parts of Alectoria asiatica Du Rietzs 50 parts of Herba Sarcopyramis nepalensis 47 parts
The Fructus Sophorae 46 Fen Herba Rorippae 42 parts of Rhizoma Polygonati Verticillatis 40 portions of Rhizoma Dioscoreaes 38 parts
27 parts, Radix Polygalae 37 portions of Herba Poae Sphondylodiss 33 parts of Herba Polygalae Japonicae 32 portions of Radix Glycyrrhizaes.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 59 parts of Periostracum cicadaes 55 parts of Poria cum Radix Pinis 54 parts of Herba Limonii Gmelinii 53 parts
Flos puerariae lobatae 49 parts of Herba Crotalariae Ferrugineaes 44 parts of Alectoria asiatica Du Rietzs 41 parts of Herba Sarcopyramis nepalensis 40 parts
The Fructus Sophorae 35 Fen Herba Rorippae 34 parts of Rhizoma Polygonati Verticillatis 33 portions of Rhizoma Dioscoreaes 30 parts
19 parts, Radix Polygalae 29 portions of Herba Poae Sphondylodiss 25 parts of Herba Polygalae Japonicae 24 portions of Radix Glycyrrhizaes.
Be used for the treatment of a preparation method for the Chinese medicine preparation of hypoglycemia, comprise following processing step:
(1) Radix Angelicae Sinensis, Rhizoma Polygonati Verticillati, Rhizoma Dioscoreae and Radix Polygalae are removed impurity, clean, put into container, spray clear water, run through rear low temperature and dry, grind into powder, cross 120 order fine powders, for subsequent use;
(2) Periostracum cicadae, Poria cum Radix Pini, Alectoria asiatica Du Rietz, Herba Sarcopyramis nepalensis and Radix Glycyrrhizae are removed impurity, clean, put into container, add 5 times amount distilled water, decoct 3 hours, extract decoction liquor; Add 3 ~ 4 times amount distilled water again, decoct 2 hours, extract decoction liquor, finally merge the decoction liquor extracted for 2 times, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(3) Herba Limonii Gmelinii, Flos puerariae lobatae and the Fructus Sophorae are removed impurity, clean, put into container and fry to tack-free, taking-up is dried in the air cool, grinds into powder, crosses 140 order fine powders, for subsequent use;
(4) Herba Crotalariae Ferrugineae, Herba Rorippae, Herba Poae Sphondylodis and Herba Polygalae Japonicae are removed impurity, clean, dry, grind into powder in placing container, cross 160 order fine powders, for subsequent use;
(5) fine powder of step (1), step (3), step (4) gained and the thick paste of step (3) gained are made tablet, be the Chinese medicine preparation being used for the treatment of hypoglycemia of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature; Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, injury from falling down, ulcer sores, promoting blood circulation to restore menstrual flow, rheumatic arthralgia, injury from falling down." detailed outline " carries: " control headache, all pains of trusted subordinate, intestine moistening stomach muscles and bones skin.Control carbuncle, evacuation of pus pain relieving, and blood is enriched blood.”
Periostracum cicadae: sweet in the mouth, cold in nature; Return lung, Liver Channel.Dispelling wind and heat pathogens, relieving spasm by subduing liver-wind, improving acuity of vision and removing nebula.For affection due to external wind and heat, heating is dizzy, infantile convulsion; Conjunctival congestion and swelling pain, pterygium." detailed outline " carries: " control headache, all pains of trusted subordinate, intestine moistening stomach muscles and bones skin.Control carbuncle, evacuation of pus pain relieving, and blood is enriched blood.”
Poria cum Radix Pini: sweet in the mouth, light, property is put down.Mind calming, calms the nerves, diuretic.For palpitation with fear of having a guilty conscience, forgetful, insomnia infantile convulsion, dysuria." book on Chinese herbal medicine is new again " carries: " controlling has a guilty conscience breathes hard, spleen invigorating profit temperature.”
Herba Limonii Gmelinii: bitter in the mouth, salty, warm in nature.Promoting blood circulation and hemostasis, warming middle-JIAO and strengthening the spleen, strengthening by means of tonics.For menoxenia, dysfunctional uterine hemorrhage, bleeding hemorrhoids, gastric ulcer, insufficiency of the spleen edema." Chinese Herbal Medicine in Xinjiang handbook " carries: " hemostasis dissipating blood stasis.Control dysfunctional uterine hemorrhage, cervical cancer and other are hemorrhage.”
Flos puerariae lobatae: sweet in the mouth, cool in nature; Return stomach warp.Relieve the effect of alcohol, be amusing, hemostasis.Thirsty for dysphoria with smothery sensation of getting sick from drinking too much wine, headache and dizzy, distension and fullness in the abdomen, vomiting acid regurgitation, anorexia, discharging fresh blood stool." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control dizziness, the loathing of cold, high fever, relieving acute alcoholism and recuperating the spleen, wine dysentery, diet is not thought, and chest and diaphragm is glutted, and send out oh, vomit sour expectorant, alcoholism injures one's stomach, and spit blood, hematemesis, disappear heat.”
Herba Crotalariae Ferrugineae: bitter in the mouth, micro-acid, cold in nature; Return lung meridian.To astringe the lung gas, spleen reinforcing kidney, diuresis, detumescence poison.For Hiccough and deaf, chronic nephritis, cystitis, renal calculus, lymphadenitis, furuncle and malignant sore." vegetation is side just " carries: " invigorating the spleen and replenishing QI, treat tinnitus, the head is giddy, collapses pouring.Pathogenic fire purging heat clearing away again, suppressing liver-wind, detumescence pain.”
Alectoria asiatica Du Rietz: lightly seasoned, property is put down.Enriching yin and nourishing kidney, inducing diuresis to remove edema.For kidney deficiency and bodily weakness, headache and dizzy, cardiopalmus is passed out semen, night sweat stranguria, edema order disease.
Herba Sarcopyramis nepalensis: sweet in the mouth, sweet, cold nature; Return lung, Liver Channel.Heat clearing away suppressing the hyperactive liver, eliminating damp, detoxifying.For cough due to lung-heat, the vertigo, Hiccough and deaf, day red photophobia, rheumatic arthralgia, traumatic injury wound is swollen, innominate toxic swelling.
The Fructus Sophorae: sweet in the mouth, large intestine channel, cool in nature.Heat clearing away profit liver, cooling blood for hemostasis.Rush down blood for hemorrhoidal hamorrhage, hemorrhoidal bleeding metrorrhagia, stranguria with blood dysentery, ambition is unhappy, dizziness due to wind pathogen for falling, erosion of vulva pruritus due to damp pathogen.Supplement to the Herbal carries: " parasite killing removes wind, and improving eyesight is except hot tears, and between brains ambition, hot blast is unhappy, and dizziness due to wind pathogen is for falling, and salivation is as liquor-saturated in mind, ripples as person on ship car.”
Herba Rorippae: sweet in the mouth, acrid in the mouth, cool in nature; Return liver, kidney channel.Antihypertensive diuretic, cooling blood for hemostasis.For dizziness, hypertension, urine heat is puckery unfavorable, hematuria, metrorrhagia leukorrhagia.
Rhizoma Polygonati Verticillati: sweet in the mouth, property is put down.Nourishing the liver and kidney, YIN nourishing and the production of body fluid promoting.For neurasthenia, hypertension, headache, throat pain, quenches one's thirst, dry mouth and tougue." Shaanxi Chinese herbal medicine " carries: " suppressing the hyperactive liver to relieve the wind syndrome, yin nourishing improving eyesight, clearing away heat and cooling blood.Control headache order disease, throat pain, vascular hypertension, epilepsy, furuncle carbuncle.”
Rhizoma Dioscoreae: sweet in the mouth, property is put down; Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst." property of medicine opinion " carries: " mend five kinds of strain and seven kinds of impairment, remove cold wind, only lumbago, relieving palpitation god, reinforcing the heart QI-insufficiency, suffers from human body weakness with emaciation, add and use it.”
Radix Polygalae: bitter in the mouth, pungent, warm in nature; GUIXIN, kidney, lung meridian.To calm the nerves Fructus Alpiniae Oxyphyllae, eliminating phlegm for diminishing swelling.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain." not Lu " carries: " centering gas, spasmolytic is throbbed with fear, benefit essence, goes heat in heart intake of food in the morning and vomitting in the evening gas, skin, appearance yellow.”
Herba Poae Sphondylodis: sweet in the mouth, light, property is put down.Inducing diuresis for treating stranguria syndrome, expels the heat-evil and calms the nerves.For hot urination, pyretic stranguria, oedema due to nephritis, dizzy toothache, epistaxis pharyngalgia, vexed insomnia, nocturnal emission of quenching one's thirst." Chinese herbal medicine is commonly used in Shanghai " carries: " control dysuria, urethra heating twinge, oedema due to nephritis, insomnia, cardiopalmus, vexed.”
Herba Polygalae Japonicae: taste is micro-pungent, warm in nature.Relieving cough and reducing sputum, promoting blood circulation and hemostasis, removing toxic substances of calming the nerves.For cough with copious phlegm, hematemesis hematochezia, palpitation with a distress feeling is had a sleepless night, laryngopharynx swelling and pain, skin sore, venom, traumatic injury." Nanning City's medicine will " carries: " heat clearing away, moisturizes, removing toxic substances.Treating snakebite, cough, spits blood, infantile malnutrition, eye conjunctivitis.”
Radix Glycyrrhizae: sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus.
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, there is invigorating the heart and spleen, nourishing the liver relieve dizziness, high fever, infantile convulsions, epilepsy, etc., supplementing QI to revive YANG, refreshment of having one's ideas straightened out effect, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, have fabulous alleviation and therapeutic effect to treatment hypoglycemia, the clinical treatment and the nursing that are suitable for hypoglycemia are applied.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Angelicae Sinensis 80g Periostracum cicadae Poria cum Radix Pini 77g 75g Herba Limonii Gmelinii 73g
Flos puerariae lobatae 70g Herba Crotalariae Ferrugineae 65g Alectoria asiatica Du Rietz 62g Herba Sarcopyramis nepalensis 60g
Fructus Sophorae 58g Herba Rorippae 55g Rhizoma Polygonati Verticillati 53g Rhizoma Dioscoreae 51g
Radix Polygalae 50g Herba Poae Sphondylodis 46g Herba Polygalae Japonicae 45g Radix Glycyrrhizae 40g.
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) Radix Angelicae Sinensis, Rhizoma Polygonati Verticillati, Rhizoma Dioscoreae and Radix Polygalae are removed impurity, clean, put into container, spray clear water, run through rear low temperature and dry, grind into powder, cross 120 order fine powders, for subsequent use;
(2) Periostracum cicadae, Poria cum Radix Pini, Alectoria asiatica Du Rietz, Herba Sarcopyramis nepalensis and Radix Glycyrrhizae are removed impurity, clean, put into container, add 5 times amount distilled water, decoct 3 hours, extract decoction liquor; Add 3 ~ 4 times amount distilled water again, decoct 2 hours, extract decoction liquor, finally merge the decoction liquor extracted for 2 times, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(3) Herba Limonii Gmelinii, Flos puerariae lobatae and the Fructus Sophorae are removed impurity, clean, put into container and fry to tack-free, taking-up is dried in the air cool, grinds into powder, crosses 140 order fine powders, for subsequent use;
(4) Herba Crotalariae Ferrugineae, Herba Rorippae, Herba Poae Sphondylodis and Herba Polygalae Japonicae are removed impurity, clean, dry, grind into powder in placing container, cross 160 order fine powders, for subsequent use;
(5) fine powder of step (1), step (3), step (4) gained and the thick paste of step (3) gained are made tablet, be the Chinese medicine preparation being used for the treatment of hypoglycemia of the present invention.
Usage and dosage: oral, the morning, noon and afternoon, respectively once each 23 days was a course for the treatment of, usual 1 ~ 2 onset course for the treatment of, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Angelicae Sinensis 74g Periostracum cicadae Poria cum Radix Pini 71g 69g Herba Limonii Gmelinii 67g
Flos puerariae lobatae 64g Herba Crotalariae Ferrugineae 59g Alectoria asiatica Du Rietz 57g Herba Sarcopyramis nepalensis 55g
Fructus Sophorae 53g Herba Rorippae 49g Rhizoma Polygonati Verticillati 47g Rhizoma Dioscoreae 45g
Radix Polygalae 44g Herba Poae Sphondylodis 40g Herba Polygalae Japonicae 39g Radix Glycyrrhizae 34g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Angelicae Sinensis 67g Periostracum cicadae Poria cum Radix Pini 64g 62g Herba Limonii Gmelinii 60g
Flos puerariae lobatae 57g Herba Crotalariae Ferrugineae 52g Alectoria asiatica Du Rietz 50g Herba Sarcopyramis nepalensis 47g
Fructus Sophorae 46g Herba Rorippae 42g Rhizoma Polygonati Verticillati 40g Rhizoma Dioscoreae 38g
Radix Polygalae 37g Herba Poae Sphondylodis 33g Herba Polygalae Japonicae 32g Radix Glycyrrhizae 27g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Angelicae Sinensis 59g Periostracum cicadae Poria cum Radix Pini 55g 54g Herba Limonii Gmelinii 53g
Flos puerariae lobatae 49g Herba Crotalariae Ferrugineae 44g Alectoria asiatica Du Rietz 41g Herba Sarcopyramis nepalensis 40g
Fructus Sophorae 35g Herba Rorippae 34g Rhizoma Polygonati Verticillati 33g Rhizoma Dioscoreae 30g
Radix Polygalae 29g Herba Poae Sphondylodis 25g Herba Polygalae Japonicae 24g Radix Glycyrrhizae 19g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
Select the routine clinical observation of hypoglycemic 520 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 260 example, wherein male 120 example, women 140 example, 18 ~ 65 years old age, 47 years old mean age, the course of disease 2 months ~ 1 year, average 10 months.Matched group 260 example, wherein male 124 example, women 136 example, 17 ~ 60 years old age, 52 years old mean age, the course of disease 1 month ~ 9 months, average 4 months.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes this Chinese medicine preparation, oral, and the morning, noon and afternoon, respectively once each 23 days was a course for the treatment of, usual 1 ~ 2 onset course for the treatment of, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Matched group takes metformin hydrochloride tablet, and initial dose is 0.5 gram, every twice-daily, or 0.85 gram, once a day, take with meal.
3, efficacy determination:
(1) cure: the transference cures such as cardiopalmus, dizziness is after meal forgotten, blood sugar test is abnormal; Conscious, health is fully recovered.
(2) effective: above-mentioned symptom is alleviated to some extent, conscious, health is fully recovered.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 221 examples, effective 24 examples, invalid 15 examples, cure rate 85%, total effective rate 94.2%.
201 examples are cured, effective 29 examples, invalid 30 examples, cure rate 77.3%, total effective rate 88.5% in matched group.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Cai's ××, female, 18 years old, student, people from Jiujiang.Patient goes into a coma without obvious inducement, on inspection blood glucose 1.8mmol/L, gives mind after glucose and recovers normal, can take food through vein, but later stage dizzy cardiopalmus, be diagnosed as hypoglycemia by my institute.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom is obviously alleviated, and continues to take 3 courses for the treatment of, and above symptom all disappears.Follow up a case by regular visits to and do not recur so far.
2, flourish ××, female, 25 years old, salesman, Gansu the Jiayu Pass people.Patient whole blood's glucose detection is less than 2.5mmol/L, and cardiopalmus after meal, forgets sometimes, uncomfortable in chestly feels bad.Be diagnosed as hypoglycemia.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, health is rehabilitation gradually, and symptom is obviously alleviated, and continues to take 2 courses for the treatment of, above transference cure.Follow up a case by regular visits to and do not recur so far.
3, father-in-law's ××, man, 29 years old, profession, people from yan-an.Patients acuity hypoglycemia, ferments, easily hungry, often perspires, and with tachycardia, the symptom such as systolic pressure raises, diastolic pressure reduces, tremble, goes into a coma sometimes.After taking 4 courses for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, and after continuing to take 2 courses for the treatment of, above transference cure, physical recovery is healthy, not recurrence.
4, in ××, man, 35 years old, detection person, Nanyang, henan people.Patient suffers from hypoglycemia, easily dizziness, anxiety, enrage, drowsiness, while attention lax, disorientation, to tremble.Take Chinese medicine preparation of the present invention 2 the symptom course for the treatment of obviously to alleviate, after continuing to take 3 courses for the treatment of, transference cure, follows up a case by regular visits to not recurrence.
5, in ××, female, 39 years old, teacher, people from Ezhou, Hubei.Patient is unconsciousness suddenly, dizzy, exhale not should, lip is without cyanosis, and jugular vein is opened without anger, neck passivity, and pulmonary is without exception, and heart circle is little, heart rate 110, arrhythmia, first heart sound power not etc., Peripheral blood glucose 2.4mmol/l.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom takes a turn for the better, and after continuing to take 3 courses for the treatment of, above transference cure, gets well, and follows up a case by regular visits to and does not recur so far.
6, ×× is opened, man, 60 years old, businessman, people from Deyang, Sichuan.After patient drinks, self-induction cardiopalmus, uncomfortable in chest, and have a little perspiration, and because symptom is comparatively light, therefore do not give attention at that time, later stage conscious cardiopalmus, exacerbation of symptoms uncomfortable in chest, panhidrosis is more, and have movable rear chest pain, Progressive symmetric erythrokeratodermia limbs fatigue, dizzy.Be diagnosed as hypoglycemia.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after then taking 2 courses for the treatment of, physical recovery is normal, and activity freely.Follow up a case by regular visits to and do not recur so far.
Claims (5)
1. be used for the treatment of a Chinese medicine preparation for hypoglycemia, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 51 ~ 81 parts of Periostracum cicadaes 48 ~ 78 parts of Poria cum Radix Pinis 46 ~ 76 parts of Herba Limonii Gmelinii 44 ~ 74 parts
Flos puerariae lobatae 41 ~ 71 parts of Herba Crotalariae Ferrugineaes 36 ~ 66 parts of Alectoria asiatica Du Rietzs 33 ~ 63 parts of Herba Sarcopyramis nepalensis 31 ~ 61 parts
The Fructus Sophorae 29 ~ 59 Fen Herba Rorippae 26 ~ 56 parts of Rhizoma Polygonati Verticillatis 24 ~ 54 portions of Rhizoma Dioscoreaes 22 ~ 52 parts
11 ~ 41 parts, Radix Polygalae 21 ~ 51 portions of Herba Poae Sphondylodiss 17 ~ 47 parts of Herba Polygalae Japonicae 16 ~ 46 portions of Radix Glycyrrhizaes.
2. be used for the treatment of a Chinese medicine preparation for hypoglycemia, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 74 parts of Periostracum cicadaes 71 parts of Poria cum Radix Pinis 69 parts of Herba Limonii Gmelinii 67 parts
Flos puerariae lobatae 64 parts of Herba Crotalariae Ferrugineaes 59 parts of Alectoria asiatica Du Rietzs 57 parts of Herba Sarcopyramis nepalensis 55 parts
The Fructus Sophorae 53 Fen Herba Rorippae 49 parts of Rhizoma Polygonati Verticillatis 47 portions of Rhizoma Dioscoreaes 45 parts
34 parts, Radix Polygalae 44 portions of Herba Poae Sphondylodiss 40 parts of Herba Polygalae Japonicae 39 portions of Radix Glycyrrhizaes.
3. be used for the treatment of a Chinese medicine preparation for hypoglycemia, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 67 parts of Periostracum cicadaes 64 parts of Poria cum Radix Pinis 62 parts of Herba Limonii Gmelinii 60 parts
Flos puerariae lobatae 57 parts of Herba Crotalariae Ferrugineaes 52 parts of Alectoria asiatica Du Rietzs 50 parts of Herba Sarcopyramis nepalensis 47 parts
The Fructus Sophorae 46 Fen Herba Rorippae 42 parts of Rhizoma Polygonati Verticillatis 40 portions of Rhizoma Dioscoreaes 38 parts
27 parts, Radix Polygalae 37 portions of Herba Poae Sphondylodiss 33 parts of Herba Polygalae Japonicae 32 portions of Radix Glycyrrhizaes.
4. be used for the treatment of a Chinese medicine preparation for hypoglycemia, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Angelicae Sinensis 59 parts of Periostracum cicadaes 55 parts of Poria cum Radix Pinis 54 parts of Herba Limonii Gmelinii 53 parts
Flos puerariae lobatae 49 parts of Herba Crotalariae Ferrugineaes 44 parts of Alectoria asiatica Du Rietzs 41 parts of Herba Sarcopyramis nepalensis 40 parts
The Fructus Sophorae 35 Fen Herba Rorippae 34 parts of Rhizoma Polygonati Verticillatis 33 portions of Rhizoma Dioscoreaes 30 parts
19 parts, Radix Polygalae 29 portions of Herba Poae Sphondylodiss 25 parts of Herba Polygalae Japonicae 24 portions of Radix Glycyrrhizaes.
5. the preparation method being used for the treatment of the Chinese medicine preparation of hypoglycemia as described in any one of Claims 1 to 4, is characterized in that: comprise following processing step:
(1) Radix Angelicae Sinensis, Rhizoma Polygonati Verticillati, Rhizoma Dioscoreae and Radix Polygalae are removed impurity, clean, put into container, spray clear water, run through rear low temperature and dry, grind into powder, cross 120 order fine powders, for subsequent use;
(2) Periostracum cicadae, Poria cum Radix Pini, Alectoria asiatica Du Rietz, Herba Sarcopyramis nepalensis and Radix Glycyrrhizae are removed impurity, clean, put into container, add 5 times amount distilled water, decoct 3 hours, extract decoction liquor; Add 3 ~ 4 times amount distilled water again, decoct 2 hours, extract decoction liquor, finally merge the decoction liquor extracted for 2 times, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(3) Herba Limonii Gmelinii, Flos puerariae lobatae and the Fructus Sophorae are removed impurity, clean, put into container and fry to tack-free, taking-up is dried in the air cool, grinds into powder, crosses 140 order fine powders, for subsequent use;
(4) Herba Crotalariae Ferrugineae, Herba Rorippae, Herba Poae Sphondylodis and Herba Polygalae Japonicae are removed impurity, clean, dry, grind into powder in placing container, cross 160 order fine powders, for subsequent use;
(5) fine powder of step (1), step (3), step (4) gained and the thick paste of step (3) gained are made tablet, be the described Chinese medicine preparation being used for the treatment of hypoglycemia.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687956A (en) * | 2016-02-26 | 2016-06-22 | 刘力 | Traditional Chinese medicine ointment for treating allergic dermatitis and preparation method |
| CN105727034A (en) * | 2016-03-30 | 2016-07-06 | 葛映东 | Medicine for treating hypoglycemia |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845694A (en) * | 2013-12-30 | 2014-06-11 | 刘翠玲 | Traditional Chinese medicine for treating hypoglycemia |
| CN104095923A (en) * | 2013-04-10 | 2014-10-15 | 赵骁栋 | Traditional Chinese medicine for treating fasting hypoglycemia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104095923A (en) * | 2013-04-10 | 2014-10-15 | 赵骁栋 | Traditional Chinese medicine for treating fasting hypoglycemia |
| CN103845694A (en) * | 2013-12-30 | 2014-06-11 | 刘翠玲 | Traditional Chinese medicine for treating hypoglycemia |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105687956A (en) * | 2016-02-26 | 2016-06-22 | 刘力 | Traditional Chinese medicine ointment for treating allergic dermatitis and preparation method |
| CN105727034A (en) * | 2016-03-30 | 2016-07-06 | 葛映东 | Medicine for treating hypoglycemia |
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