CN107149627A - Compound Chinese medicinal preparation and preparation method for treating yin-yang deficiency Anemia disease - Google Patents
Compound Chinese medicinal preparation and preparation method for treating yin-yang deficiency Anemia disease Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
A kind of compound preparation and preparation method for being used to treat yin-yang deficiency Anemia disease.Preparation by consumption by weight than agents raw material be made：Astragalus root 18 48, Radix Angelicae Sinensis 6 15, Poria cocos 9 24, prepared rhizome of rehmannia 12 32, Fructus Corni 6 15, psoralea corylifolia 9 24, barrenwort 6 15, the fruit of glossy privet 6 15, eclipta 6 15, the fruit of Chinese wolfberry 6 15, RADIX ACONITI LATERALIS PREPARATA 4 10, honey-fried licorice root 4 10.Invention formulation is to boil the method for extraction using water to extract the active ingredient in material medicine, and keeps its activity, so not only can greatly improve the dissolution rate of active ingredient in medicine, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, medicine is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term taking, so security is good.In addition, the preparation method technique of the present invention is simple, it is easy to operate.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, more particularly to a kind of use being made using Chinese medicine as raw material
In the compound preparation and preparation method for the treatment of yin-yang deficiency Anemia disease.
Background technology
Anaemia refers to that hemoglobin (Hb) concentration in peripheral blood unit volume blood, red blood cell (RBC) are counted and blood is thin
Born of the same parents' specific volume (HCT) is less than the lower limit than crowd's normal value, wherein mostly important with hemoglobin.It is " empty that anaemia belongs to traditional Chinese medicine
The category such as labor ", " jaundice ", " empty yellow ", more due to first native endowments Fu deficiency, eating and drinking without temperance, loses blood, bothers excessive, pregnant mistake for a long time
Support and serious disease prolonged illness is deficient etc. causes spleen-kidney deficiency, insufficiency of the spleen then transformation failure of spleen, no resource of generating and transforming QI and blood, then vital essence is not enough for kidney deficiency, nothing
To give birth to medullization blood, cause deficiency of qi and blood.Although the types of drugs for being clinically used to treat anemia at present is a lot, due to causing
The factor of anemia has a variety of, therefore anemia also divides polytype, so these medicine lack of targeted, the course for the treatment of is relatively
It is long, and some drugs have certain side effect or allergic reaction, thus after taking for treatment belong to it is yin-yang deficiency caused by it is poor
Effect is undesirable for this disease of blood disease.
The content of the invention
In order to solve the above problems, it is used to treat yin-yang deficiency Anemia disease it is an object of the invention to provide a kind of
Compound preparation and preparation method.
In order to achieve the above object, provided by the present invention for treat the compound preparation of yin-yang deficiency Anemia disease by with
Measure by weight than agents raw material be made：
Astragalus root 18-48 Radix Angelicae Sinensis 6-15 Poria cocos 9-24 prepared rhizome of rehmannia 12-32 Fructus Cornis 6-15
Psoralea corylifolia 9-24 barrenwort 6-15 fruit of glossy privet 6-15 eclipta 6-15 fruits of Chinese wolfberry 6-15
RADIX ACONITI LATERALIS PREPARATA 4-10 honey-fried licorice roots 4-10
The described preparation method for being used to treat the compound Chinese medicinal preparation of yin-yang deficiency Anemia disease is by said medicine
Raw material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes afterwards, filter and remove residue is that can be made into
The described compound preparation for being used to treat yin-yang deficiency Anemia disease.
Described compound Chinese medicinal preparation can be made with conventional pharmaceutic adjuvant granule, tablet, capsule, syrup,
Oral liquid, pill and paste.
Extraction is boiled using water provided by the present invention for the yin-yang deficiency Anemia for the treatment of sick compound Chinese medicinal preparation
Method extracts the active ingredient in material medicine, and keeps its activity, so can not only make the dissolution of active ingredient in medicine
Degree is greatly improved, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, the medicine of the present invention is
Pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term taking, so security is good.In addition, the present invention
Preparation method technique is simple, easy to operate.
Embodiment
Anemia complicated symptoms, course of disease delay, complication is more.Clinical common asthenic symptoms, real example and syndrome of intermingled deficiency and excess etc..This
Fang Lifa is in tonifying speen and tonifying kidney, tonifying both YIN and YANG.The sweet tepor of astragalus root in side, strengthening spleen and middle warmer, yang invigorating, benefit defends solid table, eliminating toxic life
Flesh, is the key medicine of tonifying middle-Jiao and Qi, therefore is monarch drug in a prescription.Radix Angelicae Sinensis Gan Xinwen, enriches blood, promoting blood circulation and stopping pain；The sweet tepor of prepared rhizome of rehmannia, yin-nourishing of enriching blood,
Life essence-filling, marrow-benefitting；Psoralea corylifolia toil temperature, tonifying kidney and strengthening yang, astringent sperm contracting urine；Fruit of glossy privet sweetness and bitterness is cool, nourishing liver and kidney, and crow must improving eyesight；The fruit of Chinese wolfberry
Gan Ping, nourishing liver and kidney, benefiting shrewd head, for the fine work of the smart liver blood of flat kidney tonifying, all medicines of the above fill blood, negative and positive, liver and spleen kidney, are altogether
Ministerial drug.Poria cocos is sweet light flat, clearing damp and promoting diuresis, strengthening the spleen and reducing phlegm, antitoxic heart-soothing and sedative；Tepor that Fructus Corni is sour and astringent, tonifies the liver and kidney, and convergence is astringent or styptic treatment for spontaneous sweating,
For the key medicine of flat tonifying yin sun；Barrenwort Xin Ganwen, tonifying kidney and strengthening yang, dispelling wind and eliminating dampness；Eclipta sweet acid is trembled with fear, and nourishing liver and kidney, cool blood is stopped
Blood；The pungent sweet big heat of RADIX ACONITI LATERALIS PREPARATA, recuperating depleted yang, mends fire supporing yang, eliminating cold to stop pain is the medicine of recuperating depleted yang first, and all medicines of the above, Li Shui dispels
Wind inducing astrigency, calming heart, tonifying Qi and blood, internal organs, Hui Yang is altogether adjutant.Honey-fried licorice root is sweet flat, invigorates the spleen and benefits qi, and clearing heat and detoxicating analgesic reconciles
All medicines, thinking makes medicine.We's nourishing negative and positive, while the effects such as there are tonifying Qi and blood, internal organs, therefore suitable for treating yin-yang deficiency institute
The anemia of cause.
With reference to embodiment to the compound Chinese medicinal preparation provided by the present invention for treating yin-yang deficiency Anemia disease
And preparation method thereof be described in detail.
Embodiment 1：
It is weight ratio that what the present embodiment was provided, which is used to treat the sick compound Chinese medicinal preparation of yin-yang deficiency Anemia by consumption,
Agents raw material be made：
The Fructus Corni 15 of 24 prepared rhizome of rehmannia of astragalus root 48 Radix Angelicae Sinensis, 15 Poria cocos 32
The fruit of Chinese wolfberry 15 of 15 eclipta of psoralea corylifolia 24 barrenwort, 15 fruit of glossy privet 15
The honey-fried licorice root 10 of RADIX ACONITI LATERALIS PREPARATA 10
The described preparation method for being used to treat the compound Chinese medicinal preparation of yin-yang deficiency Anemia disease is by said medicine
Raw material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes afterwards, filter and remove residue is that can be made into
The described compound preparation for being used to treat yin-yang deficiency Anemia disease.
In addition, granule, tablet, capsule, sugar can be made with conventional pharmaceutic adjuvant in described compound Chinese medicinal preparation
Starch agent, oral liquid, pill and paste.
Embodiment 2：
It is weight ratio that what the present embodiment was provided, which is used to treat the sick compound Chinese medicinal preparation of yin-yang deficiency Anemia by consumption,
Agents raw material be made：
The Fructus Corni 6 of 9 prepared rhizome of rehmannia of astragalus root 18 Radix Angelicae Sinensis, 6 Poria cocos 12
The fruit of Chinese wolfberry 6 of 6 eclipta of psoralea corylifolia 9 barrenwort, 6 fruit of glossy privet 6
The honey-fried licorice root 4 of RADIX ACONITI LATERALIS PREPARATA 4
Preparation method be the same as Example 1.
Embodiment 3：
It is weight ratio that what the present embodiment was provided, which is used to treat the sick compound Chinese medicinal preparation of yin-yang deficiency Anemia by consumption,
Agents raw material be made：
The Fructus Corni 12 of 17 prepared rhizome of rehmannia of astragalus root 22 Radix Angelicae Sinensis, 12 Poria cocos 22
The fruit of Chinese wolfberry 12 of 12 eclipta of psoralea corylifolia 17 barrenwort, 12 fruit of glossy privet 12
The honey-fried licorice root 8 of RADIX ACONITI LATERALIS PREPARATA 8
Preparation method be the same as Example 1.
Provided by the present invention for treating the compound Chinese medicinal preparation of yin-yang deficiency Anemia disease in brown to sepia；Gas
It is light, mildly bitter flavor.In order to verify the therapeutic effect of the compound Chinese medicinal preparation, the present inventor is using above-mentioned compound Chinese medicinal preparation to 324
Patient of the example with yin-yang deficiency type anemia has carried out system clinical observation, wherein 21-30 Sui patient 83,31-40 Sui 114
Example, 41-50 Sui 127, each medication 150ml, 3 times a day, is within 120 days 1 course for the treatment of.Cure (blood altogether after 1 course of therapy
Lactoferrin (Hb) concentration, red blood cell (RBC) are counted and the cardinal symptom such as hematocrit (HCT) is obviously improved) 177, account for
54.6%；Effectively (every laboratory examination is obviously improved, and cardinal symptom has improvement) 131,40.4% is accounted for；Invalid (items chemical examination
Check unchanged, cardinal symptom is without improving) 16, account for 4.9%；Total effective rate is 95.1%.Cured altogether after 2 course of therapy
241, account for 74.4%；Effective 73, account for 22.5%；Invalid 10, account for 3.1%；Total effective rate is 96.9%.
Meanwhile, the present inventor is analyzed the relation between therapeutic effect and age, therapeutic effect and the course for the treatment of, analysis
As a result 1, table 2 is shown in Table respectively.
Table 1：The compound Chinese medicinal preparation therapeutic effect that the present invention is provided and age correlations table
By the data x in above-mentioned table 12Method of inspection is calculated, and is as a result 0.050 ＞ P ＞ 0.025, it is possible thereby to demonstrate,prove
It is bright to take the compound Chinese medicinal preparation that provides of the present invention to treat yin-yang deficiency type anemia, to the therapeutic effect of each age group not with
Age and change.
Table 2：The compound Chinese medicinal preparation therapeutic effect that the present invention is provided and course for the treatment of relation table
By the data x in above-mentioned table 22Method of inspection is calculated, and is as a result P ＜ 0.005, it is possible thereby to prove to take this
Invent the compound Chinese medicinal preparation of offer to treat yin-yang deficiency type anemia, with going deep into for treatment, cure rate, effective percentage are bright
It is aobvious to improve.
Claims (3)
1. a kind of compound preparation for being used to treat yin-yang deficiency Anemia disease, it is characterised in that：Described compound preparation by with
Measure by weight than agents raw material be made：
Astragalus root 18-48 Radix Angelicae Sinensis 6-15 Poria cocos 9-24 prepared rhizome of rehmannia 12-32 Fructus Cornis 6-15
Psoralea corylifolia 9-24 barrenwort 6-15 fruit of glossy privet 6-15 eclipta 6-15 fruits of Chinese wolfberry 6-15
RADIX ACONITI LATERALIS PREPARATA 4-10 honey-fried licorice roots 4-10.
2. a kind of preparation side as claimed in claim 1 for being used to treat the compound Chinese medicinal preparation of yin-yang deficiency Anemia disease
Method, it is characterised in that：Described preparation method is that said medicine raw material is weighed and mixed according to proportioning, and then add water leaching
Bubble 25 minutes, is decocted 30 minutes afterwards, and filter and remove residue is that can be made into described to be used to treat answering for yin-yang deficiency Anemia disease
Square preparation.
3. preparation method according to claim 2, it is characterised in that：Described compound Chinese medicinal preparation can be with conventional medicine
Granule, tablet, capsule, syrup, oral liquid, pill and paste are made of auxiliary material.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710309508.3A CN107149627A (en) | 2017-05-04 | 2017-05-04 | Compound Chinese medicinal preparation and preparation method for treating yin-yang deficiency Anemia disease |
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| CN201710309508.3A CN107149627A (en) | 2017-05-04 | 2017-05-04 | Compound Chinese medicinal preparation and preparation method for treating yin-yang deficiency Anemia disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107441249A (en) * | 2017-09-14 | 2017-12-08 | 深圳市桦嘉为医药保健品科技有限公司 | The preparation method of the Chinese medicine held and its pill is supported in enriching yin of promoting longevity |
-
2017
- 2017-05-04 CN CN201710309508.3A patent/CN107149627A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 周永明: "《中医血液病临床手册》", 30 September 2005, 上海中医药大学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107441249A (en) * | 2017-09-14 | 2017-12-08 | 深圳市桦嘉为医药保健品科技有限公司 | The preparation method of the Chinese medicine held and its pill is supported in enriching yin of promoting longevity |
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Application publication date: 20170912 |