CN107519297A - Treat the preparation and preparation method of Qi dysfunction in blood control caused thrombocytopenic purpura - Google Patents

Treat the preparation and preparation method of Qi dysfunction in blood control caused thrombocytopenic purpura Download PDF

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Publication number
CN107519297A
CN107519297A CN201710916838.9A CN201710916838A CN107519297A CN 107519297 A CN107519297 A CN 107519297A CN 201710916838 A CN201710916838 A CN 201710916838A CN 107519297 A CN107519297 A CN 107519297A
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preparation
dysfunction
medicine
thrombocytopenic purpura
blood
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马力
王维蔚
齐燕松
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Tianjin City Hongxing Good Economic Technology Development Co Ltd
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Abstract

A kind of preparation and preparation method for treating Qi dysfunction in blood control caused thrombocytopenic purpura.Preparation by dosage by weight than agents raw material be made：The Radix Astragali 18 48, Radix Codonopsis 6 15, rhizoma atractylodis macrocephalae 9 24, Poria cocos 9 24, dried orange peel 6 15, prepared rhizome of rehmannia 9 24, Radix Angelicae Sinensis 6 15, stir-baked RADIX PAEONIAE ALBA 9 24, Colla Corii Asini bead 6 15, Semen Ziziphi Spinosae (parched) 9 24, arillus longan 6 15, jujube 9 24, honey-fried licorice root 4 10.Invention formulation is to extract the active ingredient in material medicine using the method for boiling extraction, and keeps its activity, so not only can greatly improve the dissolution rate of active ingredient in medicine, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, the medicine of the present invention is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term use, so security is good.In addition, preparation method technique is simple, it is easy to operate.

Description

Treat the preparation and preparation method of Qi dysfunction in blood control caused thrombocytopenic purpura
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, is used more particularly to one kind using Chinese medicine as made of raw material In the compound Chinese medicinal preparation and preparation method for the treatment of Qi dysfunction in blood control caused thrombocytopenic purpura.
Background technology
Thrombocytopenic purpura is a kind of common hemorrhagic disease, can be divided into two kinds of primary and Secondary cases.It is primary Caused by property is due to mostly autoimmunity, Secondary cases can be caused by many reasons, and both clinical manifestations are similar.Thrombocytopenic No matter primary purpura is or secondary, with the petechia of skin and mucous membrane, ecchymosis, or has visceral hemorrhage, platelet count is definitely reduced to Clinical symptoms, thus belong to the categories such as " blood trouble " of motherland's medical science, " hair spot ".Although clinically subtract at present for treating blood platelet The types of drugs of few property purpura is more but a variety of due to causing the factor of thrombocytopenic purpura to have, and decrease of platelet Property purpura also divide polytype, therefore these medicine lack of targeted, the course for the treatment of is relatively long, and some drugs have certain secondary make With or allergic reaction, so after taking for treatment belong to it is Qi dysfunction in blood control caused by this disease of thrombocytopenic purpura for DeGrain.
The content of the invention
In order to solve the above problems, subtract it is an object of the invention to provide one kind for treating Qi dysfunction in blood control caused blood platelet Compound Chinese medicinal preparation of few property purpura and preparation method thereof.
In order to achieve the above object, it is provided by the invention treatment it is Qi dysfunction in blood control caused by thrombocytopenic purpura preparation by Dosage by weight than agents raw material be made：
Radix Astragali 18-48 Radix Codonopsis 6-15 rhizoma atractylodis macrocephalae 9-24 Poria cocos 9-24 dried orange peels 6-15
Prepared rhizome of rehmannia 9-24 Radix Angelicae Sinensis 6-15 stir-baked RADIX PAEONIAE ALBA 9-24 Colla Corii Asini bead 6-15 Semen Ziziphi Spinosae (parched)s 9-24
Arillus longan 6-15 jujube 9-24 honey-fried licorice roots 4-10
The preparation method of the preparation of thrombocytopenic purpura caused by described treatment is Qi dysfunction in blood control is that said medicine is former Material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes afterwards, filter and remove residue can be made into institute That states is used to treat the compound Chinese medicinal preparation of Qi dysfunction in blood control caused thrombocytopenic purpura.
Described compound Chinese medicinal preparation can be made with conventional pharmaceutic adjuvant granule, tablet, capsule, syrup, Oral liquid, pill and paste.
It is to use provided by the present invention for the compound Chinese medicinal preparation for treating Qi dysfunction in blood control caused thrombocytopenic purpura The method of boiling extraction extracts the active ingredient in material medicine, and keeps its activity, so can not only make in medicine effectively The dissolution rate of composition greatly improves, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, this hair Bright medicine is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term use, so security is good.This Outside, preparation method technique of the invention is simple, easy to operate.
Embodiment
Akembe shape is complicated, course of disease delay, and complication is more.Clinical common asthenic symptoms, real example and actual situation It is mingled with card etc..This side makes laws in replenishing qi to invigorate the spleen, and blood is taken the photograph in blood-nourishing.The sweet tepor of the Radix Astragali in side, strengthening spleen and middle warmer, yang invigorating, benefit are defended solid Table, diuresis, promoting pus discharge and tissue regeneration, be tonifying middle-Jiao and Qi key medicine, therefore be monarch drug in a prescription.Radix Codonopsis is sweet flat, tonifying spleen lung qi, enriches blood, promotes the production of body fluid；Poria cocos is sweet It is light flat, clearing damp and promoting diuresis, strengthening the spleen and reducing phlegm, antitoxic heart-soothing and sedative；The sweet tepor of prepared rhizome of rehmannia, yin-nourishing of enriching blood, life essence-filling, marrow-benefitting；Stir-baked RADIX PAEONIAE ALBA picric acid is micro- Cold, the moon, soft liver analgesic, suppressing liver-YANG are held back in blood-nourishing；Semen Ziziphi Spinosae (parched) sweet acid is put down, and nourishing heart benefit liver, is calmed the nerves, arrest sweating；The sweet temperature of jujube, bowl spares QI invigorating, nourishing blood and tranquilization, all medicines of the above, yin-nourishing are calmed the nerves, filled blood, and clearing damp invigorating the spleen, are altogether ministerial drug.Rhizoma atractylodis macrocephalae sweetness and bitterness temperature, QI invigorating are good for Spleen, eliminating dampness diuresis, it is the key medicine of air making-up and spleen enlivening first；The arduous temperature of dried orange peel, regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm；Radix Angelicae Sinensis Gan Xinwen, enriches blood, Promoting blood circulation and stopping pain；Colla Corii Asini bead is sweet flat, tonifies the blood and arrest bleeding, nourishing Yin and moistening lung, for the key medicine enriched blood；The sweet temperature of arillus longan, tonifying heart and spleen, blood-nourishing peace God, all medicines of the above, replenishes qi to invigorate the spleen, nourishing yin and supplementing blood, eliminating dampness qi-regulating, is adjutant.Honey-fried licorice root is sweet flat, invigorates the spleen and benefits qi, clearing heat and detoxicating to stop Bitterly, coordinating the drug actions of a prescription, thinking makes medicine.Our qi-regulating eliminating dampness, replenishes qi to invigorate the spleen, nourishing yin and nourishing blood, therefore suitable for Qi dysfunction in blood control caused blood Platelet reduction property purpura.
With reference to embodiment to provided by the present invention for treating in Qi dysfunction in blood control caused thrombocytopenic purpura Medicine compound preparation and preparation method thereof is described in detail.
Embodiment 1：
The present embodiment provide be used for treat it is Qi dysfunction in blood control caused by thrombocytopenic purpura compound Chinese medicinal preparation by with Measure by weight than agents raw material be made：
It is described be used to treating it is Qi dysfunction in blood control caused by the preparation method of compound Chinese medicinal preparation of thrombocytopenic purpura be Said medicine raw material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes, filter off afterwards Slag is that can be made into the described compound Chinese medicinal preparation for being used to treat Qi dysfunction in blood control caused thrombocytopenic purpura.
In addition, granule, tablet, capsule, sugar can be made with conventional pharmaceutic adjuvant in described compound Chinese medicinal preparation Starch agent, oral liquid, pill and paste.
Embodiment 2：
The present embodiment provide be used for treat it is Qi dysfunction in blood control caused by thrombocytopenic purpura compound Chinese medicinal preparation by with Measure by weight than agents raw material be made：
Preparation method is the same as embodiment 1.
Embodiment 3：
The present embodiment provide be used for treat it is Qi dysfunction in blood control caused by thrombocytopenic purpura compound Chinese medicinal preparation by with Measure by weight than agents raw material be made：
Preparation method is the same as embodiment 1.
It is in brown provided by the present invention for the compound Chinese medicinal preparation for treating Qi dysfunction in blood control caused thrombocytopenic purpura To sepia；Gas is light, mildly bitter flavor.In order to verify the therapeutic effect of the compound Chinese medicinal preparation, the present inventor is answered using above-mentioned Chinese medicine Square preparation has carried out system clinical observation, wherein 21-30 to 325 patients with Qi dysfunction in blood control type thrombocytopenic purpura Year patient 88,31-40 year 122,41-50 year 115, each medication 150ml, 3 times a day, 120 days are 1 course for the treatment of.Through 1 (bleeding disappears substantially) 149 is cured altogether after individual course of therapy, accounts for 45.8%；Effectively (cardinal symptom has improvement) 155, Account for 47.7%；Invalid (cardinal symptom is without improvement) 21, accounts for 6.5%；Total effective rate is 93.5%.After 2 course of therapy altogether 215 are cured, accounts for 66.2%；Effective 93, account for 28.6%；Invalid 17, account for 5.2%；Total effective rate is 94.8%.
Meanwhile the present inventor is analyzed the relation between therapeutic effect and age, therapeutic effect and the course for the treatment of, analysis As a result 1, table 2 is shown in Table respectively.
Table 1：Compound Chinese medicinal preparation therapeutic effect provided by the invention and age correlations table
By the data x in above-mentioned table 12Method of inspection is calculated, and is as a result 0.050 ＞ P ＞ 0.025, it is possible thereby to demonstrate,prove It is bright to take compound Chinese medicinal preparation provided by the invention to treat Qi dysfunction in blood control type thrombocytopenic purpura, each age group is controlled Therapeutic effect does not change with the age.
Table 2：Compound Chinese medicinal preparation therapeutic effect provided by the invention and course for the treatment of relation table
By the data x in above-mentioned table 22Method of inspection is calculated, and is as a result P ＜ 0.005, it is possible thereby to prove to take this The compound Chinese medicinal preparation provided is provided and treats Qi dysfunction in blood control type thrombocytopenic purpura, with going deep into for treatment, cure rate, Effective percentage significantly improves.

Claims (3)

  1. A kind of 1. preparation for treating Qi dysfunction in blood control caused thrombocytopenic purpura, it is characterised in that：It is described to be used to treat gas The preparation of thrombocytopenic purpura caused by not taking the photograph blood by dosage by weight than agents raw material be made：
    Radix Astragali 18-48 Radix Codonopsis 6-15 rhizoma atractylodis macrocephalae 9-24 Poria cocos 9-24 dried orange peels 6-15
    Prepared rhizome of rehmannia 9-24 Radix Angelicae Sinensis 6-15 stir-baked RADIX PAEONIAE ALBA 9-24 Colla Corii Asini bead 6-15 Semen Ziziphi Spinosae (parched)s 9-24
    Arillus longan 6-15 jujube 9-24 honey-fried licorice roots 4-10.
  2. 2. a kind of preparation method for the preparation for treating Qi dysfunction in blood control caused thrombocytopenic purpura as claimed in claim 1, It is characterized in that：Described preparation method is that said medicine raw material is weighed and mixed according to proportioning, is then soaked 25 minutes, decoct 30 minutes afterwards, filter and remove residue be can be made into it is described be used to treating it is Qi dysfunction in blood control caused by thrombocytopenic The compound Chinese medicinal preparation of purpura.
  3. 3. preparation method according to claim 2, it is characterised in that：Described compound Chinese medicinal preparation can be with conventional medicine Granule, tablet, capsule, syrup, oral liquid, pill and paste is made with auxiliary material.
CN201710916838.9A 2017-09-30 2017-09-30 Treat the preparation and preparation method of Qi dysfunction in blood control caused thrombocytopenic purpura Withdrawn CN107519297A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432381A (en) * 2022-01-25 2022-05-06 中国中医科学院西苑医院 Traditional Chinese medicine composition and preparation method and application thereof
CN115429851A (en) * 2022-10-20 2022-12-06 贵州中医药大学第二附属医院 Deer-horn qi-tonifying and blood-generating pill and preparation process and application thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
焦中华等: "《实用中医血液病学》", 30 June 1989, 青岛出版社 *
邝玉子: "归脾汤为主治疗慢性特发性血小板减少性紫癜40例", 《新中医》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114432381A (en) * 2022-01-25 2022-05-06 中国中医科学院西苑医院 Traditional Chinese medicine composition and preparation method and application thereof
CN115429851A (en) * 2022-10-20 2022-12-06 贵州中医药大学第二附属医院 Deer-horn qi-tonifying and blood-generating pill and preparation process and application thereof
CN115429851B (en) * 2022-10-20 2024-01-23 贵州中医药大学第二附属医院 Deer crystal qi-tonifying blood-generating pill and preparation process and application thereof

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