CN107184784A - Treat deficiecny of liver-YIN, the sick compound Chinese medicinal preparation of deficient Anemia and preparation method - Google Patents
Treat deficiecny of liver-YIN, the sick compound Chinese medicinal preparation of deficient Anemia and preparation method Download PDFInfo
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
One kind treats deficiecny of liver-YIN, the sick compound Chinese medicinal preparation of deficient Anemia and preparation method.Preparation by consumption by weight than agents raw material be made:Prepared rhizome of rehmannia 12 32, Radix Angelicae Sinensis 6 15, stir-baked RADIX PAEONIAE ALBA 9 24, Ligusticum wallichii 6 15, the wind-weed 9 24, radix scrophulariae 9 24, Fructus Corni 6 15, the fleece-flower root 6 15, the fruit of glossy privet 6 15, the fruit of Chinese wolfberry 6 15, chrysanthemum 4 10, radix bupleuri 4 10.Invention formulation is to boil the method for extraction using water to extract the active ingredient in material medicine, and keeps its activity, so not only can greatly improve the dissolution rate of active ingredient in medicine, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, medicine is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term taking, so security is good.In addition, the preparation method technique of the present invention is simple, it is easy to operate.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, more particularly to a kind of use being made using Chinese medicine as raw material
In treatment deficiecny of liver-YIN, the compound Chinese medicinal preparation and preparation method of deficient Anemia disease.
Background technology
Anaemia refers to that hemoglobin (Hb) concentration in peripheral blood unit volume blood, red blood cell (RBC) are counted and blood is thin
Born of the same parents' specific volume (HCT) is less than the lower limit than crowd's normal value, wherein mostly important with hemoglobin.It is " empty that anaemia belongs to traditional Chinese medicine
The category such as labor ", " jaundice ", " empty yellow ", more due to first native endowments Fu deficiency, eating and drinking without temperance, loses blood, bothers excessive, pregnant mistake for a long time
Support and serious disease prolonged illness is deficient etc. causes spleen-kidney deficiency, insufficiency of the spleen then transformation failure of spleen, no resource of generating and transforming QI and blood, then vital essence is not enough for kidney deficiency, nothing
To give birth to medullization blood, cause deficiency of qi and blood.Although the types of drugs for being clinically used to treat anemia at present is a lot, due to causing
The factor of anemia has a variety of, therefore anemia also divides polytype, so these medicine lack of targeted, the course for the treatment of is relatively
It is long, and some drugs have certain side effect or allergic reaction, so belong to deficiecny of liver-YIN for treatment after taking, it is deficient caused
This disease of anemia for effect it is undesirable.
The content of the invention
In order to solve the above problems, it is used to treat deficiecny of liver-YIN it is an object of the invention to provide one kind, it is deficient caused poor
The compound Chinese medicinal preparation and preparation method of blood disease.
In order to achieve the above object, provided by the present invention for treatment deficiecny of liver-YIN, the Chinese medicine of deficient Anemia disease is answered
Square preparation by consumption by weight than agents raw material be made:
Prepared rhizome of rehmannia 12-32 Radix Angelicae Sinensis 6-15 stir-baked RADIX PAEONIAE ALBA 9-24 Ligusticum wallichii 6-15 wind-weed 9-24 radix scrophulariaes 9-24
Fructus Corni 6-15 fleece-flower root 6-15 fruit of glossy privet 6-15 fruit of Chinese wolfberry 6-15 chrysanthemum 4-10 radix bupleuri 4-10
Described to be used to treat deficiecny of liver-YIN, the preparation method of the compound Chinese medicinal preparation of deficient Anemia disease is will be above-mentioned
Medicine material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes afterwards, filter and remove residue
Described treatment deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease is made.
Described compound Chinese medicinal preparation can be made with conventional pharmaceutic adjuvant granule, tablet, capsule, syrup,
Oral liquid, pill and paste.
Provided by the present invention for treatment deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease is to boil to carry using water
The method taken extracts the active ingredient in material medicine, and keeps its activity, so can not only make active ingredient in medicine
Dissolution rate is greatly improved, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, the medicine of the present invention
Thing is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term taking, so security is good.In addition, this hair
Bright preparation method technique is simple, easy to operate.
Embodiment
Anemia complicated symptoms, course of disease delay, complication is more.Clinical common asthenic symptoms, real example and syndrome of intermingled deficiency and excess etc..This
Fang Lifa is in nourishing hepatic yin, blood-nourishing honor muscle.The sweet tepor of prepared rhizome of rehmannia, yin-nourishing of enriching blood, life essence-filling, marrow-benefitting is monarch drug in a prescription.Radix Angelicae Sinensis Gan Xinwen, is mended
Blood, promoting blood circulation and stopping pain;Ligusticum wallichii pungent-warm, blood-activating and qi-promoting, wind-expelling pain-stopping;Radix scrophulariae sweetness and bitterness is salty to be slightly cold, clearing heat and cooling blood, purging intense heat and detonicating, enriching yin;
The puckery tepor of fleece-flower root bitter sweet, help essence and blood;The fruit of Chinese wolfberry is sweet flat, nourishing liver and kidney, benefiting shrewd head, for the fine work of the smart liver blood of flat kidney tonifying,
The all medicines of the above, nourishing yin and nourishing blood fills up essence and blood, is altogether ministerial drug.Stir-baked RADIX PAEONIAE ALBA picric acid is slightly cold, and the moon is held back in blood-nourishing, and liver is stabilized in soft liver analgesic
Sun;Wind-weed bitter sweet is trembled with fear, clearing heat-fire, fluid dryness;Tepor that Fructus Corni is sour and astringent, tonifies the liver and kidney, and convergence is astringent or styptic treatment for spontaneous sweating, for flat tonifying yin sun
Key medicine;Fruit of glossy privet sweetness and bitterness is cool, nourishing liver and kidney, and crow must improving eyesight;Chrysanthemum work hard it is sweet be slightly cold, dispelling wind and heat from the body, suppressing liver-YANG, clear liver it is bright
Mesh, clearing heat and detoxicating, all medicines of the above, clearing heat and moistening dryness, blood-nourishing of promoting the production of body fluid, suppressing liver-YANG is altogether adjutant.Radix bupleuri hardship is flat to be slightly cold, soothing the liver solution
It is strongly fragrant, rise and lift yang-energy, priming is up, and thinking makes medicine.Our nourishing qi and blood, nourishing liver and kidney, sharp water invigorating the spleen, with qi-restoratives labor, replenishing essence
The work(of blood, therefore suitable for treatment deficiecny of liver-YIN, deficient caused anemia.
With reference to embodiment to provided by the present invention for treatment deficiecny of liver-YIN, the Chinese medicine compound prescription of deficient Anemia disease
Preparation and preparation method thereof is described in detail.
Embodiment 1:
The present embodiment is used to treat deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease by consumption be weight than
Agents raw material is made:
The radix scrophulariae 24 of 15 wind-weed of prepared rhizome of rehmannia 32 Radix Angelicae Sinensis, 15 stir-baked RADIX PAEONIAE ALBA, 24 Ligusticum wallichii 24
The radix bupleuri 10 of 15 chrysanthemum of Fructus Corni 15 fleece-flower root, 15 fruit of glossy privet, 15 fruit of Chinese wolfberry 10
Described to be used to treat deficiecny of liver-YIN, the preparation method of the compound Chinese medicinal preparation of deficient Anemia disease is will be above-mentioned
Medicine material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes afterwards, filter and remove residue
Described treatment deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease is made.
In addition, granule, tablet, capsule, sugar can be made with conventional pharmaceutic adjuvant in described compound Chinese medicinal preparation
Starch agent, oral liquid, pill and paste.
Embodiment 2:
The present embodiment is used to treat deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease by consumption be weight than
Agents raw material is made:
The radix scrophulariae 9 of 6 wind-weed of prepared rhizome of rehmannia 12 Radix Angelicae Sinensis, 6 stir-baked RADIX PAEONIAE ALBA, 9 Ligusticum wallichii 9
The radix bupleuri 4 of 6 chrysanthemum of Fructus Corni 6 fleece-flower root, 6 fruit of glossy privet, 6 fruit of Chinese wolfberry 4
Preparation method be the same as Example 1.
Embodiment 3:
The present embodiment is used to treat deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease by consumption be weight than
Agents raw material is made:
The radix scrophulariae 17 of 12 wind-weed of prepared rhizome of rehmannia 22 Radix Angelicae Sinensis, 12 stir-baked RADIX PAEONIAE ALBA, 17 Ligusticum wallichii 17
The radix bupleuri 8 of 12 chrysanthemum of Fructus Corni 12 fleece-flower root, 12 fruit of glossy privet, 12 fruit of Chinese wolfberry 8
Preparation method be the same as Example 1.
Provided by the present invention for treatment deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease is in brown to brown
Color;Gas is light, mildly bitter flavor.In order to verify the therapeutic effect of the compound Chinese medicinal preparation, the present inventor utilizes above-mentioned compound Chinese medicinal preparation
335 are suffered from deficiecny of liver-YIN, the patient of deficient type anemia has carried out system clinical observation, wherein 21-30 Sui patient 92,
31-40 Sui 126,41-50 Sui 117, each medication 150ml, 3 times a day, is within 120 days 1 course for the treatment of.Through 1 course of therapy
Cure altogether afterwards (cardinal symptom such as hemoglobin (Hb) concentration, red blood cell (RBC) counting and hematocrit (HCT) is obviously improved)
171, account for 51.0%;Effectively (every laboratory examination is obviously improved, and cardinal symptom has improvement) 135,40.3% is accounted for;It is invalid
(every laboratory examination is unchanged, and cardinal symptom is without improvement) 29, accounts for 8.7%;Total effective rate is 91.3%.Controlled through 2 courses for the treatment of
236 are cured after treatment altogether, 70.4% is accounted for;Effective 91, account for 27.2%;Invalid 8, account for 2.4%;Total effective rate is 97.6%.
Meanwhile, the present inventor is analyzed the relation between therapeutic effect and age, therapeutic effect and the course for the treatment of, analysis
As a result 1, table 2 is shown in Table respectively.
Table 1:The compound Chinese medicinal preparation therapeutic effect that the present invention is provided and age correlations table
By the data x in above-mentioned table 12Method of inspection is calculated, and is as a result 0.050 > P > 0.025, it is possible thereby to demonstrate,prove
Bright to take the compound Chinese medicinal preparation of the invention provided to treat deficiecny of liver-YIN, deficient type anemia controls curative effect to each age group
Fruit does not change with the age.
Table 2:The compound Chinese medicinal preparation therapeutic effect that the present invention is provided and course for the treatment of relation table
By the data x in above-mentioned table 22Method of inspection is calculated, and is as a result P < 0.005, it is possible thereby to prove to take this
Invent the compound Chinese medicinal preparation that provides to treat deficiecny of liver-YIN, deficient type anemia, with going deep into for treatment, cure rate, effectively
Rate is significantly improved.
Claims (3)
1. one kind treats deficiecny of liver-YIN, the compound Chinese medicinal preparation of deficient Anemia disease, it is characterised in that:Described Chinese medicine compound prescription
Preparation by consumption by weight than agents raw material be made:
Prepared rhizome of rehmannia 12-32 Radix Angelicae Sinensis 6-15 stir-baked RADIX PAEONIAE ALBA 9-24 Ligusticum wallichii 6-15 wind-weed 9-24 radix scrophulariaes 9-24
Fructus Corni 6-15 fleece-flower root 6-15 fruit of glossy privet 6-15 fruit of Chinese wolfberry 6-15 chrysanthemum 4-10 radix bupleuri 4-10.
2. a kind for the treatment of deficiecny of liver-YIN as claimed in claim 1, the preparation side of the compound Chinese medicinal preparation of deficient Anemia disease
Method, it is characterised in that:Described preparation method is that said medicine raw material is weighed and mixed according to proportioning, and then add water leaching
Bubble 25 minutes, is decocted 30 minutes, filter and remove residue is that can be made into described treatment deficiecny of liver-YIN afterwards, in deficient Anemia disease
Medicine compound preparation.
3. preparation method according to claim 2, it is characterised in that:Described compound Chinese medicinal preparation can be with conventional medicine
Granule, tablet, capsule, syrup, oral liquid, pill and paste are made of auxiliary material.
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Non-Patent Citations (1)
Title |
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周永明: "《中医血液病临床手册》", 30 September 2005, 上海中医药大学出版社 * |
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