CN111686048B

CN111686048B - Anti-aging essence and preparation method thereof

Info

Publication number: CN111686048B
Application number: CN202010664235.6A
Authority: CN
Inventors: 孙胜
Original assignee: Guangzhou Shengmei Cosmetics Co ltd
Current assignee: Guangzhou Shengmei Cosmetics Co ltd
Priority date: 2020-07-10
Filing date: 2020-07-10
Publication date: 2021-02-02
Anticipated expiration: 2040-07-10
Also published as: CN111686048A

Abstract

The invention discloses anti-aging essence and a preparation method thereof, and relates to the field of skin care products. The anti-aging essence comprises the following components: tremella heteropolysaccharide, xanthan gum, EDTA, carbome 20, glycerol, 1, 3-butanediol, glycerol glucoside PTG, glyceryl polyether-26, white willow bark extract, geranium tenuissimae extract, plantain seed extract, lactobacillus fermentation lysate, yeast zinc, water-soluble fullerene, tripeptide, Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, Eyeliss dipeptide-2 and palmitoyl tetrapeptide-7, Gekko Swinhonis, Helichrysum arenaria, Helichrysum arenarium pressure relieving anti-inflammatory extract, triethanolamine, silk peptide solution, phenoxyethanol, E-1008, Stephania tetrandra extract, CO-40, essence, menthyl lactate and water. It has good anti-aging effect, safety, high efficiency, and certain speckle removing performance.

Description

Anti-aging essence and preparation method thereof

Technical Field

The invention relates to the field of skin care products, and particularly relates to anti-aging essence and a preparation method thereof.

Background

Skin aging is a natural law and is the result of the combined action of the intrinsic physiological mechanism of human aging and the damage caused by external wind, sunshine, environmental pollution and the like. An important phenomenon of skin aging is skin wrinkling, which is a wrinkling phenomenon caused by the fact that the skin naturally loses moisture under the wash of a long river and cannot be effectively supplemented in time. Therefore, anti-aging, one of the important points is to moisturize and prevent the generation of wrinkles. Another important point of anti-aging is to replace aging cells in time, i.e., to promote cell neogenesis.

In the prior art, synthetic active ingredients such as acetylated hexapeptide in peptide anti-aging and anti-wrinkle ingredients are basically added to anti-wrinkle and anti-aging products, and the generation of expression lines and fine wrinkles is essentially inhibited by blocking the muscle nerve transmission speed, and the active ingredients often generate dependence after being used, so that the skin can be restored after not being used, and even the skin is deteriorated because the active ingredients do not have nourishing and regulating effects on the skin. With the progress of society and the improvement of the living standard of people, the requirements of people on the quality and the performance of cosmetics are higher and higher, the cosmetics are not limited to the mixture of chemical raw material products, and the theory and the research result of multiple subjects such as skin physiology, psychology, pharmacology and the like need to be combined, so that the requirements of people on the cosmetics are met on different levels. The existing whitening, freckle-removing and anti-aging products on the market are full of pearls, but the skin cuticle can be thinned and shed after a plurality of products are used for a long time, so that the skin resistance is reduced, more new color spots are formed, and the skin is not beneficial to further skin care; in addition, because the skin types of individuals are different, the effect of the same anti-aging product on different individuals can be completely different, and therefore, the research and development of safer and new anti-aging essence have important significance.

Chinese patent application 201911090726.8 discloses a skin care cream and a preparation method thereof, belonging to the technical field of daily skin care products, comprising an A phase, a B phase, a C phase and a D phase, wherein the A phase comprises 1, 3-propylene glycol, glycerol, p-hydroxyacetophenone, purslane extract and the like; phase B comprises isononyl isononanoate, dioctyl carbonate, caprylic/capric triglyceride, etc.; the phase C comprises Margarita powder, matrine, and erythritol; phase D comprises potato starch, extract of Angelica maritima leaf and stem, Chinese herbal extract, Chinese herbal root powder, etc., and water; heating, homogenizing, stirring, keeping warm, cooling, mixing, discharging and filling to obtain the finished product. The beauty cream provided by the invention has remarkable acne removing, water replenishing, repairing and anti-aging effects, and is mild and safe for skin.

The Chinese patent application 201810416759.6 is a lotus whitening, moisturizing and anti-aging essence and a preparation method thereof, wherein the whitening, moisturizing and anti-aging essence comprises the following components: 85 to 100 percent of water, 1 to 5.0 percent of lotus extract, 1.0 to 3.0 percent of butanediol, 1.0 to 2.0 percent of pentanediol, 1.0 to 2.0 percent of betaine, 0.1 to 1.0 percent of trehalose, 0.1 to 0.3 percent of hyaluronic acid, 0.1 to 0.5 percent of hydrolyzed beta-glucan, 0.1 to 0.2 percent of allantoin, 0.1 to 0.1 percent of cymoxanil, 0.1 to 0.2 percent of imidazolidinyl urea and 0.1 percent of essence. According to the whitening, moisturizing and anti-aging essence disclosed by the invention, raw material components are organically combined according to a certain mass fraction, and the prepared whitening, moisturizing and anti-aging essence has a good repairing effect and excellent cold and hot stability, has an anti-aging function, and improves the skin elasticity.

However, the components added in the beauty products are limited, and the synergistic anti-aging effect is not better than that of the compatibility of various components, so that the anti-aging essence provided by the invention has the advantages that the anti-aging effect is good, the skin elasticity is improved, the wrinkle is reduced, the safety and the efficiency are high, the good reaction hardly occurs, and the certain freckle removing effect is realized.

Disclosure of Invention

The invention aims to provide anti-aging essence and a preparation method thereof, and the anti-aging essence has a safe and efficient anti-aging function. According to the invention, by adding a plurality of plant extract formulas and adjusting a proper compounding ratio, the anti-aging effect of the product is effectively improved.

In order to achieve the purpose, the technical scheme of the invention is as follows:

an anti-aging essence comprises the following components: tremella heteropolysaccharide, xanthan gum, EDTA, carbome 20, glycerol, 1, 3-butanediol, glycerol glucoside PTG, glyceryl polyether-26, white willow bark extract, geranium tenuissimae extract, plantain seed extract, lactobacillus fermentation lysate, yeast zinc, water-soluble fullerene, tripeptide, Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, Eyeliss dipeptide-2 and palmitoyl tetrapeptide-7, Gekko Swinhonis, Helichrysum arenaria, Helichrysum arenarium pressure relieving anti-inflammatory extract, triethanolamine, silk peptide solution, phenoxyethanol, E-1008, Stephania tetrandra extract, CO-40, essence, menthyl lactate and water.

Wherein the weight ratio of the white willow bark extract, the geranium wilfordii extract, the plantain seed extract and the tetrandra root extract is 2:2:0.8-1.2:2-3, and the preferable weight ratio is 2:2:1: 3.

Preferably, the anti-aging essence comprises the following components in parts by weight: 0.12-0.18 part of tremella heteropolysaccharide, 0.08-0.12 part of transparent xanthan gum, 0.015-0.025 part of EDTA, 0.25-0.22 part of carbomer U200.18, 4-6 parts of glycerol, 7-9 parts of 1, 3-butanediol, 4-6 parts of glycerol-glucose PTG, 262.5-3.5 parts of glycerol polyether, 0.18-0.22 part of white willow bark extract, 0.18-0.22 part of geranium gracilis extract, 0.08-0.12 part of plantain seed extract, 0.4-0.6 part of lactobacillus fermentation lysate, 0.4-0.6 part of yeast zinc, 0.03-0.05 part of water-soluble fullerene, 0.08-0.12 part of tripeptide, 0.06-1 part of Haloxyy palmitoyl tripeptide and 0. 70.18-0.22 part of palmitoyl tetrapeptide, Eyeliss-2 and palmitoyl tetrapeptide-70.18-0.22 part of anti-inflammatory agent, 0.6 part of Sjogren-0.04 part of Sjogren-6 part of Sjogren tea tree, 0.04-0.04 part of S, 0.16-0.20 part of triethanolamine, 1.5-2.5 parts of silk peptide liquid, 0.2-0.3 part of phenoxyethanol, 1.2-1.78 parts of E-10080.8, 0.2-0.4 part of tetrandra root extract, 0.3532-0.06 part of CO-400.04, 0.004-0.006 part of essence, 0.06-0.10 part of menthyl lactate and 70-80 parts of water.

Further preferably, the anti-aging essence comprises the following components in parts by weight: 0.15 part of tremella heteropolysaccharide, 0.1 part of transparent xanthan gum, 0.02 part of EDTA, 200.2 parts of carbomer U, 5 parts of glycerol, 8 parts of 1, 3-butanediol, 5 parts of glycerol glucoside PTG, 0.2 part of glycerol polyether-263, 0.2 part of white willow bark extract, 0.2 part of geranium tenuipilum extract, 0.1 part of plantain seed extract, 0.5 part of lactobacillus fermentation lysate, 0.5 part of yeast zinc, 0.04 part of water-soluble fullerene, 0.1 part of tripeptide, 1 and 70.2 parts of Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide, 0.2 part of Eyeliss dipeptide-2 and palmitoyl tetrapeptide-70.2, 0.5 part of Geranium vesii, 0.05 part of Helichrysum arenarium press anti-inflammatory refined extract, 0.18 part of triethanolamine, 2 parts of silk peptide solution, 0.25 part of phenoxy ethanol, E-10081.0 parts of radix Stephaniae Tetrandrae extract, 0.3 parts of essence extract, 0. 400.05 parts of CO-005, 0.74 parts of lactic acid.

On the other hand, the invention also provides a preparation method of the anti-aging essence, which comprises the following steps:

(1) pouring tremella heteropolysaccharide, transparent xanthan gum, EDTA, carbome 20, glycerol, 1, 3-butanediol, glycerol glucoside PTG, glyceryl polyether-26, white willow bark extract, geranium wilfordii extract, plantain seed extract, lactobacillus fermentation lysate, yeast zinc, water-soluble fullerene, tripeptide, Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, Eyeliss dipeptide-2 and palmitoyl tetrapeptide-7, Gekko Swinhonis, Helichrysum cinerascens, triethanolamine, silk peptide liquid, phenoxyethanol, E-1008, Stephania tetrandra extract, CO-40 and water into a reaction kettle, heating to 75-90 ℃ to obtain phase A;

(2) pouring the essence and menthyl lactate with the formula dosage into a reaction kettle, and heating to 70-85 ℃ to obtain a phase B;

(3) homogenizing the phase A, cooling in vacuum, pouring the phase B while stirring when the temperature is reduced to 40-45 ℃, continuously stirring until the temperature is 35-40 ℃, and discharging by using a 100-mesh filter screen after the product control initial inspection is qualified to obtain the anti-aging essence.

Preferably, in step (1), the temperature is 82 ℃.

Preferably, in step (2), the temperature is 76 ℃.

Preferably, in the step (3), the homogenization is performed at 50Hz for 15 to 35 minutes, and more preferably for 25 minutes.

Preferably, in the step (3), the temperature is reduced to 42 ℃.

Preferably, in the step (3), the stirring speed for pouring the phase B while stirring is 40 to 50 revolutions per minute, and more preferably 45 revolutions per minute.

Preferably, in step (3), the stirring is continued to 35-40℃, in particular 38℃.

Compared with the prior art, the invention has the following beneficial effects:

by adding various plant extract components and synergistic action, the anti-aging cream has good anti-aging effect, improves the skin elasticity, reduces the generation of wrinkles, is safe and efficient, hardly generates good reaction, and has a certain freckle removing effect.

Detailed Description

The present invention will be further explained with reference to specific examples in order to make the technical means, the technical features, the technical objectives and the effects of the present invention easier to understand, but the following examples are only preferred embodiments of the present invention, and not all embodiments of the present invention. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative efforts belong to the protection scope of the present invention.

In the following examples, unless otherwise specified, all the procedures and equipment used were conventional procedures and equipment used was conventional equipment.

In the examples below, white willow bark extract was obtained from siebol total chemical (shanghai) ltd; the Geranium tenuifolium extract is purchased from Henan Tianfu chemical Co., Ltd; plantago seed extract was purchased from sienna biotechnology limited; stephania tetrandra extract was purchased from Shanghai Xinkai pharmaceutical science and technology Limited; e-1008 (caprylhydroxamic acid/ethylhexylglycerol) was purchased from Karma chemical Co., Guangzhou; CO-40 (hydrogenated castor oil) was purchased from Nanjing Chen Runji chemical Co., Ltd.

In the examples below, Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 were purchased from Wuhan Yingyuan Bei Biotech Ltd; eyeliss dipeptide-2 and palmitoyl tetrapeptide-7 were purchased from Simian spring Biotech, Inc.

Examples 1 to 5

The formulations of examples 1-5 are shown in Table 1:

table 1.

Comparative examples 1 to 5

The formulations of comparative examples 1-5 are shown in Table 2:

table 2.

Preparation example

The formulations of the above examples and comparative examples were prepared according to the following procedure:

(1) pouring tremella heteropolysaccharide, transparent xanthan gum, EDTA, carbome 20, glycerol, 1, 3-butanediol, glycerol glucoside PTG, glyceryl polyether-26, white willow bark extract, geranium wilfordii extract, plantain seed extract, lactobacillus fermentation lysate, yeast zinc, water-soluble fullerene, tripeptide, Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, Eyeliss dipeptide-2 and palmitoyl tetrapeptide-7, Gekko Swinhonis, Helichrysum cinerascens, triethanolamine, silk peptide solution, phenoxyethanol, E-1008, Stephania tetrandra extract, CO-40 and water into a reaction kettle, heating to 82 ℃ to obtain phase A;

(2) pouring the essence and menthyl lactate with the formula dosage into a reaction kettle, and heating to 76 ℃ to obtain a phase B;

(3) homogenizing the phase A at 50HZ for 25 min, vacuum cooling, cooling to 42 deg.C, adding phase B under stirring at 45 rpm, stirring to 38 deg.C, and discharging with 100 mesh sieve to obtain the final product.

Result detection

1. Safety test

The safety performance test is carried out on the anti-aging essence samples to be tested obtained in the examples and the comparative examples, and the method comprises the following steps:

(1) red blood cell hemolysis experiment;

preparation of erythrocyte suspension: selecting healthy rabbits, taking 9mL of blood from heart, adding 1mL of 2% potassium oxalate solution, centrifuging, discarding supernatant, diluting the precipitate to 20mL with 20mmol/L PBS solution, and storing at 4 ℃ for later use. Samples to be tested are selected to be diluted to different concentrations by PBS solution, and each sample to be tested is provided with 5 concentration gradients. Taking 10mL of a diluent of a sample to be tested, adding 200 μ L of the erythrocyte suspension (controlling the final concentration of the sample to be 5, 10, 20, 50 and 100mg/mL respectively), taking distilled water as a total blood-dissolving control, taking a PBS solution as a negative control, gently mixing, incubating for 30min at 37 ℃, centrifuging for 10min at the rotating speed of 2000r/min, taking a supernatant, testing the absorbance (A560) of the supernatant at 560nm by using a spectrophotometer, and calculating the hemolysis rate according to the following formula;

hemolysis rate ═ 100% (experimental group a 560-negative control group a560) ×/(whole hemolysis control group a 560-negative control group a560)

A standard curve of hemolysis rate vs. sample concentration was plotted and the sample concentration at which 50% of the erythrocytes were hemolyzed was calculated (HD 50).

(2) Protein denaturation experiments:

diluting a sample to be detected to 10g/L by using a PBS solution, taking 10mL of a diluent of the sample to be detected, adding 200 mu L of the erythrocyte suspension, taking distilled water as a blank control, taking 1mg/mL of a Sodium Dodecyl Sulfate (SDS) solution as a positive control, gently mixing, incubating for 30min at 37 ℃, centrifuging for 10min at the rotating speed of 2000r/min, taking a supernatant, respectively testing the absorbances A540 and A575 at 540nm and 575nm by using a spectrophotometer, and calculating the protein Denaturation Index (DI) according to the following formula;

DI＝(R1-R2)×100％/(R1-R3)

wherein, R1 is blank control group A575/blank control group A540, R2 is experiment group A575/experiment group A540, R3 is positive control group A575/positive control group A540.

And evaluating the irritation of the sample to be tested according to the L/D value, wherein the L/D value is HD50/DI, and the irritation grading standard of the erythrocyte hemolysis experiment is as follows:

when the L/D is more than 100, the classification is nonirritating; when L/D is more than 10 and less than or equal to 100, the micro-irritation is graded; when L/D is more than 1 and less than or equal to 10, grading the stimulation to be mild stimulation; when L/D is more than 0.1 and less than or equal to 1, grading to be moderate irritation;

the results of the above-described erythrocyte hemolysis experiment and protein denaturation experiment are shown in Table 3.

Table 3.

According to the safety performance test results, the anti-aging essence is mild and non-irritant; the concentration HD50 of the sample solution prepared by the invention is above 20000mg/L when 50% of erythrocytes are hemolyzed, and the protein denaturation index DI is below 0.75%, which shows that the anti-aging essence can obviously reduce toxic and side effects and irritation, and is safer and more reliable.

2. Wrinkle and speckle test

In each group of examples and comparative examples, 20 female volunteers aged 20-50 were respectively found, 5 fixed areas of 2cm square were drawn on the face in an indoor environment at 20 ℃ and 50% relative humidity, the whitening, soothing and antiaging essence and the commercially available ordinary antiaging essence of examples and comparative examples were used in the fixed areas, and spots, wrinkles and red blood streak were measured with a visia skin detector after continuous use for 15 days and 30 days (the increase in percentage indicates that the skin becomes better), and the measurement results are shown in tables 4 and 5, respectively.

TABLE 4 test results using 15 days

TABLE 5 test results using 30 days

	Wrinkle (percentile)	Spots (percentile)
			Example 1	77	70
Example 2	70	62
			Example 3	71	64
Example 4	75	67
			Example 5	73	65
Comparative example 1	38	32
			Comparative example 2	48	31
Comparative example 3	46	35
			Comparative example 4	39	38
Comparative example 5	74	66
			General essence on the market	14	9

The result shows that the whitening, soothing and anti-aging essence has great improvement on spots and wrinkles of the skin of a test person after the essence is used for one skin period, and the essence has certain freckle removing effect while achieving the anti-aging effect. Wherein, the effect of the example 1 is the best, and the comparative examples 1 to 4 show that the effect is greatly reduced if any one of the white willow bark extract, the geranium wilfordii extract, the plantain seed extract and the tetrandra root extract is lacked, so that the four components are proved to have the synergistic effect, but the effect is not correspondingly further improved if the components are additionally added in the comparative example 5, so that the cost is considered during the preparation, and the proper proportion and the proper amount are selected.

3. Skin elasticity test

Germany CK company: skin elasticity Cotometer MPA580 host, revisometer RV600 elasto-fibrous tissue test probe. 30 normal female volunteers of 35-45 years old were searched, the anti-aging essence prepared in example 1 was uniformly applied to the face, and used in the morning and evening each day without using other cosmetics for 8 weeks, and R2, R5, R7 of the skin in the test areas of 1 week, 3 weeks, 5 weeks, and 7 weeks were respectively tested, and the anti-aging efficacy of the skin of the product was evaluated by testing the changes in the values of R2, R5, and R7 of the skin before and after use, and the test of the same subject was performed by the same measurer. Test area: the forehead area 2cm above the middle of the eyebrow, the chin area 2cm below the middle of the lower lip, and the left and right cheek areas at the intersection of the nose tip and the pupil. Also, the blank values of R2, R5, R7 30min after cleaning of the test area were measured as a control before use (week 0).

R2 ═ Ua/Uf, R5 ═ Ur/Ue, R7 ═ Ur/Uf, Uf — maximum skin stretch; ue — after a constant negative pressure is applied to the skin; the amount of stretching of the skin at 0.1 second, the amount of stretching of the elastic portion is located; ur-after negative pressure is eliminated, the skin can quickly recover to the original state, and the skin is also divided into an elastic part value Ur, namely, after the negative pressure is eliminated for 0.1 second, the recovery value and the viscoelastic part value, or called as a plastic part value, of the skin; ua-the recovery value of the skin from the removal of negative pressure to the next successive test of the skin surface plus negative pressure. The closer to 1 the R2, R5, R7, the better the skin elasticity.

The product was evaluated for skin anti-aging efficacy by testing the changes in R2, R5, R7 values of the skin before and after use, as shown in table 6.

TABLE 6

	R2	R5	R7
				0 week	0.5778	0.4802	0.4427
1 week	0.5932	0.5726	0.5521
				3 weeks	0.7596	0.7708	0.7065
5 weeks	0.9121	0.9006	0.8366
				7 weeks	0.9388	0.9164	0.8832

As can be seen from table 6, example 1 can improve skin elasticity well after application, and after 7 weeks of continuous application, R2, R5, and R7 were all increased to 0.85 or more, achieving good anti-aging effect.

The present invention is not limited to the above-described preferred embodiments, but rather, the present invention is to be construed broadly and cover all modifications, equivalents, and improvements falling within the spirit and scope of the present invention.

Claims

1. An anti-aging essence is characterized by comprising the following components: tremella heteropolysaccharide, transparent xanthan gum, EDTA, carbome 20, glycerol, 1, 3-butanediol, glycerol glucoside PTG, glyceryl polyether-26, white willow bark extract, geranium tenuifolium extract, plantain seed extract, lactobacillus fermentation lysate, yeast zinc, water-soluble fullerene, tripeptide, Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, Eyeliss dipeptide-2 and palmitoyl tetrapeptide-7, Vaniothalania elegans, Helichrysum arenarium-Schum pressure-relieving anti-inflammatory refined extract, triethanolamine, silk peptide liquid, phenoxyethanol, E-1008, tetrandra extract, CO-40, essence, menthyl lactate and water, wherein the weight ratio of the white willow bark extract, the geranium wilfordii extract, the plantain seed extract and the tetrandra powder extract is 2:2:0.8-1.2: 2-3.

2. The anti-aging essence according to claim 1, wherein the weight ratio of the white willow bark extract, the geranium wilfordii extract, the plantain seed extract and the tetrandra root extract is 2:2:1: 3.

3. The anti-aging essence is characterized by comprising the following components in parts by weight: 0.12-0.18 part of tremella heteropolysaccharide, 0.08-0.12 part of transparent xanthan gum, 0.015-0.025 part of EDTA, 0.25-0.22 part of carbomer U200.18, 4-6 parts of glycerol, 7-9 parts of 1, 3-butanediol, 4-6 parts of glycerol-glucose PTG, 262.5-3.5 parts of glycerol polyether, 0.18-0.22 part of white willow bark extract, 0.18-0.22 part of geranium gracilis extract, 0.08-0.12 part of plantain seed extract, 0.4-0.6 part of lactobacillus fermentation lysate, 0.4-0.6 part of yeast zinc, 0.03-0.05 part of water-soluble fullerene, 0.08-0.12 part of tripeptide, 0.06-1 part of Haloxyy palmitoyl tripeptide and 0. 70.18-0.22 part of palmitoyl tetrapeptide, Eyeliss-2 and palmitoyl tetrapeptide-70.18-0.22 part of anti-inflammatory agent, 0.6 part of Sjogren-0.04 part of Sjogren-6 part of Sjogren tea tree, 0.04-0.04 part of S, 0.16-0.20 part of triethanolamine, 1.5-2.5 parts of silk peptide liquid, 0.2-0.3 part of phenoxyethanol, 1.2-1.78 parts of E-10080.8, 0.2-0.4 part of tetrandra root extract, 0.3532-0.06 part of CO-400.04, 0.004-0.006 part of essence, 0.06-0.10 part of menthyl lactate and 70-80 parts of water.

4. The anti-aging essence according to claim 3, characterized by comprising the following components in parts by weight: 0.15 part of tremella heteropolysaccharide, 0.1 part of transparent xanthan gum, 0.02 part of EDTA, 200.2 parts of carbomer U, 5 parts of glycerol, 8 parts of 1, 3-butanediol, 5 parts of glycerol glucoside PTG, 0.2 part of glycerol polyether-263, 0.2 part of white willow bark extract, 0.2 part of geranium tenuipilum extract, 0.1 part of plantain seed extract, 0.5 part of lactobacillus fermentation lysate, 0.5 part of yeast zinc, 0.04 part of water-soluble fullerene, 0.1 part of tripeptide, 1 and 70.2 parts of Haloxy palmitoyl tripeptide-1 and palmitoyl tetrapeptide, 0.2 part of Eyeliss dipeptide-2 and palmitoyl tetrapeptide-70.2, 0.5 part of Geranium vesii, 0.05 part of Helichrysum arenarium press anti-inflammatory refined extract, 0.18 part of triethanolamine, 2 parts of silk peptide solution, 0.25 part of phenoxy ethanol, E-10081.0 parts of radix Stephaniae Tetrandrae extract, 0.3 parts of essence extract, 0. 400.05 parts of CO-005, 0.74 parts of lactic acid.

5. The method for preparing the anti-aging essence according to any one of claims 1 to 4, comprising the steps of:

6. The method according to claim 5, wherein the temperature in the step (1) is 82 ℃.

7. The method according to claim 5, wherein the temperature in the step (2) is 76 ℃.

8. The method according to claim 5, wherein the step (3) of homogenizing the mixture is performed at 50Hz for 15-35 min.

9. The process according to claim 5, wherein in the step (3), the stirring speed of the phase B poured while stirring is 40 to 50 rpm.