CN108771643B - Nourishing and moistening repair essence - Google Patents

Nourishing and moistening repair essence Download PDF

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CN108771643B
CN108771643B CN201810946692.7A CN201810946692A CN108771643B CN 108771643 B CN108771643 B CN 108771643B CN 201810946692 A CN201810946692 A CN 201810946692A CN 108771643 B CN108771643 B CN 108771643B
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parts
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cosmetic composition
adenine dinucleotide
skin
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CN108771643A (en
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左宏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The invention provides a moistening repair essence, which does not contain preservatives, pigments, alcohol, components containing ethylene oxide polymers and spices, and the composition specifically comprises the following components: 0.1-10 parts of acetyl chitosamine, 0.1-10 parts of tetrandra root extract, 0.1-10 parts of crabapple seed oil, 0.1-10 parts of lavender oil and 0.1-10 parts of nicotinamide adenine dinucleotide. The moistening repair essence disclosed by the invention has the effects of resisting skin aging, brightening skin color and repairing sensitive skin.

Description

Nourishing and moistening repair essence
Technical Field
The invention relates to the field of cosmetics, in particular to a moisturizing and repairing cosmetic composition for repairing sensitive skin.
Background
In recent years, with the improvement of the living standard of people in China, the appearance and tidy habit is gradually changed, people increasingly pay attention to the appearance of the people, and the sales volume of the Chinese cosmetic industry is remarkably increased. According to statistical data, the market scale of the Chinese cosmetic industry in 2016 is 3339 hundred million yuan. However, the pressure of life and work of modern urban people is increased, the natural environment is continuously deteriorated, and meanwhile, due to improper and excessive use of skin care products of consumers and use of hormone-containing Sanwu products, data show that the trend of Chinese allergic people and the frequency of allergy rapidly rises from 2012 to 2016. According to the data disclosed in the Chinese consensus on diagnosis and treatment of sensitive skin, the incidence rate of sensitive skin in Asian women is 40-55.98%. Wherein, although the incidence rate of Chinese women is lower than the average level, the incidence rate also reaches 36.1 percent, and one of every three Chinese women is sensitive skin. Thus, anti-allergy is becoming more and more of a concern to consumers, and consumer demand for such products is also increasing.
The exact meaning of sensitive skin has not been agreed upon. Sensitive skin is generally considered to be a highly intolerant skin condition, a multifactorial syndrome that is subject to irritation by various factors resulting in subjective symptoms of stinging, burning, tightness, itching, etc., with normal skin appearance or with mild desquamation, erythema and dryness. Sensitive skin is caused by many reasons, but is generally considered to be an abnormal function of the keratinous barrier (enhanced skin permeability) and a reduced tolerance to irritation. The best way to address these populations is to help them restore, reestablish the keratinous barrier and reduce and lessen the irritation to the skin to restore skin health.
The prior art also exists for compositions for repairing sensitive skin. For example, CN107375022A discloses a skin care composition for repairing sensitive skin. The skin care composition for repairing sensitive skin comprises the following components in parts by mass: 30.05-0.1 part of ceramide, 1-2 parts of crab apple seed oil, 1-5 parts of silanediol salicylate and 1-5 parts of beta-glucan, and has a good effect of repairing sensitive skin. CN103284912A discloses a sensitive skin cream, which is prepared from water, glycerin, dioctyl carbonate, Butyrospermum parkii fruit oil, petrolatum, cetostearyl alcohol, vitamin E, sorbitan stearate, polysorbate-60, polydimethylsiloxane, licorice root extract, wild soybean protein, hydrolyzed yeast protein, horse chestnut extract, aloe extract, bisabolol, hydrolyzed collagen, sodium hyaluronate, allantoin, lavender flower water and bis-hydroxymethyl imidazolidinyl urea, and can delay skin aging. CN104688622B discloses a self-foaming essence which contains acetylcysteine, nicotinamide and other ingredients, can obviously improve the skin state, make the skin tender and bright and fade wrinkles.
However, the skin care products available in the prior art, especially on the market, contain more component additives, such as preservatives, pigments, alcohols, oils of mineral origin and fragrances, which may cause irritation to the skin. Meanwhile, different formulations bring different skin care effects, but overall, the effect of restoring and rebuilding the keratin barrier still needs to be further improved.
On the basis of the prior art, the invention provides a reasonably-formulated moistening repair essence which does not contain irritant ingredients, and the combination of the acetyl chitosamine, the tetrandra root (STEPHANIA TETRANDRA) extract, the crabapple fruit (CALOPHYLLUM INOPHYLLUM) seed oil, the lavender (LAVANDULA ANGUSTIFOLIA) oil and the nicotinamide adenine dinucleotide in the essence helps the skin to recover and rebuild the function of a cutin barrier, and simultaneously maximally reduces the irritation to the skin, so that sensitive skin can be better repaired.
Disclosure of Invention
Aiming at the defects in the prior art, through a large number of experiments and researches of the inventor, the nourishing and moisturizing essence does not contain preservatives, pigments, alcohol, components containing ethylene oxide polymers and spices, and eliminates factors which can cause skin irritation.
The moistening and repairing essence disclosed by the invention is prepared from raw materials such as acetylcysteine, an extract of tetrandra root (STEPHANIA TETRANDRA), a seed oil of crabapple (CALOPHYLLUM INOPHYLLUM), an oil of lavender (LAVANDULA ANGUSTIFOLIA), nicotinamide adenine dinucleotide and the like, and an optimal formula component is obtained.
The acetyl chitosamine and Malus spectabilis (Calophyllum INOPHYLLUM) seed oil in the formula can repair damaged cell membrane and enhance skin barrier function; radix Stephaniae Japonicae (STEPHANIA TETRANDRA) extract and Lavandula Angustifolia (Lavandula ANGUSTIFOLIA) oil have effects of relieving pain, sterilizing, killing bacteria, relieving skin congestion and swelling, and reducing skin allergy symptoms; the nicotinamide adenine dinucleotide can resist free radicals, enhance cell activity and enhance cell immunity.
The reasonable combination of the acetyl chitosamine, the tetrandra root (STEPHANIA TETRANDRA) extract, the crabapple (CALOPHYLLUM INOPHYLLUM) seed oil, the lavender (LAVANDULA ANGUSTIFOLIA) oil and the nicotinamide adenine dinucleotide can enhance the skin barrier, reduce the skin allergy symptom and enhance the cell immunity, and simultaneously, the preservative, the pigment, the alcohol, the component containing the ethylene oxide polymer and the spice are not contained, and the effect of repairing the sensitive skin is realized after the long-term use.
The moistening repair essence provided by the invention has the effects of resisting skin aging, brightening skin color and repairing sensitive skin.
After a large number of people try out and summarize, the use feeling of the moistening repair essence disclosed by the invention is as follows: soft, smooth, soft and moist.
In particular, the present invention provides a moisturizing cosmetic composition comprising: 0.1-10 parts of acetyl chitosamine, 0.1-10 parts of tetrandra root extract, 0.1-10 parts of crabapple seed oil, 0.1-10 parts of lavender oil and 0.1-10 parts of nicotinamide adenine dinucleotide.
The cosmetic composition is one or more of cream, ointment, emulsion, film, gel and essence.
The moisturizing and repairing cosmetic composition further comprises: emulsifiers and humectants.
The moisturizing and repairing cosmetic composition further comprises: one or more of a thickener, a skin conditioner, an antioxidant.
The moisturizing and repairing cosmetic composition comprises the following emulsifying agents: cetearyl glucoside, cetyl alcohol, glyceryl stearate, cetyl glucoside, and coco glucoside.
The moisturizing and repairing cosmetic composition comprises the following moisturizers: one or more of glycerol, glycerol glucoside, propylene glycol, butanediol, sodium hyaluronate, betaine, and polyglycerol-10.
The moisturizing and repairing cosmetic composition comprises the following thickening agents: one or more of hydroxyethyl cellulose, xanthan gum, acryloyl dimethyl ammonium taurate/VP copolymer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer.
The skin conditioning agent is: one or more of tocopherol acetate, hydrogenated polydecene, polydimethylsiloxane and ethylhexyl palmitate.
The moisturizing and repairing cosmetic composition comprises the following antioxidants: one or more of glycerol glucoside, butylated hydroxytoluene, pentaerythritol tetrakis (di-tert-butyl hydroxyhydrocinnamate), sodium benzotriazolyl butylphenol sulfonate, butanol polyether-3 and tributyl citrate.
The moisturizing and repairing cosmetic composition comprises:
0.1-10 parts by weight of acetylcysteine
0.1-10 parts by weight of tetrandra root extract
0.1-10 parts by weight of crab apple seed oil
0.1-10 parts by weight of lavender oil
0.1-10 parts by weight of nicotinamide adenine dinucleotide
0.1-5 parts by weight of emulsifier
2-20 parts by weight of humectant
0.1-5 parts by weight of thickener
0.1-5 parts by weight of skin conditioning agent
1-8 parts by weight of an antioxidant.
The moisturizing and repairing cosmetic composition comprises:
1-5 parts by weight of acetylcysteine
0.5-5 parts by weight of tetrandra root extract
0.5-5 parts by weight of crab apple seed oil
0.1-2 parts by weight of lavender oil
0.1-5 parts by weight of nicotinamide adenine dinucleotide
0.1-5 parts by weight of emulsifier
5-15 parts by weight of humectant
0.1-5 parts by weight of thickener
0.1-3 parts by weight of skin conditioning agent
1-5 parts by weight of an antioxidant.
The moisturizing and repairing cosmetic composition comprises:
3 parts by weight of acetylcysteine
1 part by weight of Stephania tetrandra extract
0.5 weight part of crab apple seed oil
0.2 parts by weight of lavender oil
1 part by weight of nicotinamide adenine dinucleotide
0.6 parts by weight of emulsifier
13 parts by weight of a humectant
0.22 parts by weight of a thickener
0.5 parts by weight of skin conditioning agent
4 parts by weight of an antioxidant.
The nicotinamide adenine dinucleotide is obtained through biological fermentation.
The biological fermentation is mainly obtained by yeast extraction and separation.
The yeast extraction and separation method comprises the following specific steps: fresh squeezing yeast, wall breaking, extraction, extracting solution, separation, filtrate, primary adsorption and elution, primary eluent, neutralization, secondary adsorption, elution, tertiary adsorption and elution, tertiary eluent, precipitation, filtration and drying, and nicotinamide adenine dinucleotide.
The process for moisturizing the cosmetic composition of the present invention comprises the steps of: heating emulsifier, Malus spectabilis fruit seed oil and oleum Lavandula Angustifolia to obtain mixture 1, heating water and humectant to obtain mixture 2, mixing mixture 1 and mixture 2, homogenizing, cooling to 30-60 deg.C, and adding acetyl chitosamine, radix Stephaniae Japonicae extract and nicotinamide adenine dinucleotide.
Preferably, the formula content of the nourishing and repairing essence milk is shown in the following table:
Figure BDA0001770397900000051
Figure BDA0001770397900000061
Figure BDA0001770397900000071
the preparation method of the moistening and repairing essence milk comprises the following steps:
adding the phase A raw material into an oil phase pot, heating to 77 ℃, and stirring until the phase A raw material is completely melted;
2, adding the phase B raw material into a water phase pot, heating to 77 ℃, and completely dissolving;
3. pumping all the raw materials in the water phase pot into an emulsifying pot, and pumping the raw materials in the oil phase pot into the emulsifying pot while stirring;
4. after all the raw materials are extracted, adding the C-phase raw materials into an emulsifying pot, starting homogenizing at 3000 r/min for 5 minutes, stopping homogenizing, stirring at 30 r/min, and starting cooling;
5. cooling to 60 deg.C, adding D phase raw material, stirring at constant speed, and continuously cooling;
6. cooling to 45 ℃, adding the E-phase raw material, keeping the stirring speed unchanged, and continuously cooling;
7. cooling to 40 ℃, adding the F-phase raw material, keeping the stirring speed unchanged, stirring uniformly, starting vacuum, and continuing stirring for 30 minutes.
Preferably, the formula content of the nourishing and repairing essence cream is shown in the following table:
Figure BDA0001770397900000072
Figure BDA0001770397900000081
Figure BDA0001770397900000091
the preparation method of the moistening and repairing essence cream comprises the following steps:
adding the phase A raw material into an oil phase pot, heating to 77 ℃, and stirring until the phase A raw material is completely melted;
2, adding the phase B raw material into a water phase pot, heating to 77 ℃, and completely dissolving;
3. pumping all the raw materials in the water phase pot into an emulsifying pot, and pumping the raw materials in the oil phase pot into the emulsifying pot while stirring;
4. after all the raw materials are extracted, adding the C-phase raw materials into an emulsifying pot, starting homogenizing at 3000 r/min for 5 minutes, stopping homogenizing, stirring at 30 r/min, and starting cooling;
5. cooling to 60 deg.C, adding D phase raw material, stirring at constant speed, and continuously cooling;
6. cooling to 45 ℃, adding the E-phase raw material, keeping the stirring speed unchanged, and continuously cooling;
7. cooling to 40 ℃, adding the F-phase raw material, keeping the stirring speed unchanged, stirring uniformly, starting vacuum, and continuing stirring for 30 minutes.
Detailed Description
The present invention will be further described with reference to the following embodiments.
Example 1 moisturizing and repairing essence cream
Figure BDA0001770397900000092
Figure BDA0001770397900000101
Example 2 moisturizing repair cream
Figure BDA0001770397900000102
Figure BDA0001770397900000111
EXAMPLE 3 Effect test
To demonstrate the effectiveness of the cosmetic compositions provided herein, we prepared in parallel 5 comparative example serum milks containing different active ingredients, relative to example 1. Volunteers were tested on the moisturizing and repairing essence milk obtained in example 1 and 5 corresponding comparative examples, and the effectiveness of the moisturizing and repairing essence milk was evaluated, wherein 30 volunteers in each group were arranged, and the skin was sensitive skin after the age of 25-45 years; the using method comprises the following steps: taking a proper amount of moistening and repairing essence milk, uniformly coating the essence milk on the face, gently massaging the face until the essence milk is absorbed, and continuously using the essence milk for 8 weeks, wherein the essence milk is taken once in the morning and at night every day; the evaluation method comprises the following steps: observed once a week, the test group was effective when more than 80% of the sensitive skin phenomena were cured and recorded as effective in the next week, and the test results are shown in the following table: example 1 containing Nicotinamide 1%, Acetylchitosamine 3%, Stephania tetrandra extract 1%, Malus spectabilis fruit seed oil 0.5%, Lavender oil 0.2%, Nicotinamide adenine dinucleotide 1%)
Figure BDA0001770397900000121
EXAMPLE 4 Effect test
To demonstrate the effectiveness of the cosmetic compositions provided herein, we prepared in parallel 5 comparative example creams containing different active ingredients with respect to example 1. Volunteers who test the moisturizing and repairing essence cream obtained in example 2 and the corresponding 5 comparative examples are evaluated for effectiveness, and 30 volunteers are arranged in each group, and are all sensitive skins at the age of 25-45 years; the using method comprises the following steps: taking a proper amount of moistening and repairing essence milk, uniformly coating the essence milk on the face, gently massaging the face until the essence milk is absorbed, and continuously using the essence milk for 8 weeks, wherein the essence milk is taken once in the morning and at night every day; the evaluation method comprises the following steps: observed once a week, the test group was effective when more than 80% of the sensitive skin phenomena were cured and recorded as effective in the next week, and the test results are shown in the following table: example 1 containing Nicotinamide 1%, Acetylchitosamine 3%, radix Stephaniae Tetrandrae extract 1%, Malus spectabilis fruit seed oil 1%, Lavender oil 0.2%, and Nicotinamide adenine dinucleotide 1%)
Figure BDA0001770397900000122
Figure BDA0001770397900000131
The results obtained by comparative experiments can be seen as follows:
examples 1 and 2 compared with 5 comparative examples, the moisturizing and repairing essence cream and cream obtained in the examples of the invention have the best healing effect on sensitive skin.
The foregoing description is a general description of the invention. Although specific terms are employed herein, they are used in a generic and descriptive sense only and not for purposes of limitation, as form changes and equivalents may be employed. Various changes or modifications may be effected therein by one skilled in the art and equivalents may be made thereto without departing from the scope of the invention as defined in the claims appended hereto.

Claims (8)

1.A moisturizing cosmetic composition comprising: 0.1-10 parts of acetyl chitosamine, 0.1-10 parts of tetrandra root extract, 0.1-10 parts of crabapple seed oil, 0.1-10 parts of lavender oil and 0.1-10 parts of nicotinamide adenine dinucleotide.
2. The moisturizing repair cosmetic composition of claim 1, wherein the cosmetic composition is one of a cream, a lotion, a film, a gel, and an essence.
3. The moisturizing cosmetic composition of claim 1 or 2, further comprising: emulsifiers and humectants.
4. The moisturizing cosmetic composition of claim 3, further comprising: one or more of a thickener, a skin conditioner, an antioxidant.
5. The moisturizing cosmetic composition of claim 4, wherein the emulsifier is: one or more of cetearyl glucoside, cetyl alcohol, glyceryl stearate, cetyl glucoside, and coco glucoside;
the humectant is as follows: one or more of glycerol, glycerol glucoside, propylene glycol, butanediol, sodium hyaluronate, betaine, and polyglycerol-10;
the thickening agent is: one or more of hydroxyethyl cellulose, xanthan gum, acryloyl dimethyl ammonium taurate/VP copolymer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer;
the skin conditioning agent is: one or more of tocopherol acetate, hydrogenated polydecene, polydimethylsiloxane and ethylhexyl palmitate;
the antioxidant is as follows: one or more of glycerol glucoside, butylated hydroxytoluene, pentaerythritol tetrakis (di-tert-butyl hydroxyhydrocinnamate), sodium benzotriazolyl butylphenol sulfonate, butanol polyether-3 and tributyl citrate.
6. The moisturizing cosmetic composition of claim 1, comprising:
0.1 to 10 parts by weight of acetylcysteine;
0.1-10 parts by weight of tetrandra root extract;
0.1-10 parts by weight of crab apple seed oil;
0.1-10 parts by weight of lavender oil;
0.1-10 parts by weight of nicotinamide adenine dinucleotide;
0.1-5 parts by weight of an emulsifier;
2-20 parts by weight of a humectant;
0.1-5 parts by weight of a thickener;
0.1-5 parts by weight of a skin conditioning agent;
1-8 parts by weight of an antioxidant.
7. The moisturizing cosmetic composition of claim 1, comprising:
1-5 parts by weight of acetylcysteine;
0.5-5 parts by weight of tetrandra root extract;
0.5-5 parts by weight of crab apple seed oil;
0.1-2 parts by weight of lavender oil;
0.1-5 parts by weight of nicotinamide adenine dinucleotide;
0.1-5 parts by weight of an emulsifier;
5-15 parts by weight of a humectant;
0.1-5 parts by weight of a thickener;
0.1-3 parts by weight of a skin conditioning agent;
1-5 parts by weight of an antioxidant;
wherein, the nicotinamide adenine dinucleotide is obtained by biological fermentation; the biological fermentation is obtained by yeast extraction and separation; the yeast extraction and separation method comprises the following specific steps: fresh squeezing yeast, wall breaking, extraction, extracting solution, separation, filtrate, primary adsorption and elution, primary eluent, neutralization, secondary adsorption, elution, tertiary adsorption and elution, tertiary eluent, precipitation, filtration and drying, and nicotinamide adenine dinucleotide.
8. A method of preparing a moisturizing cosmetic composition of claim 1, comprising the steps of: heating emulsifier, Malus spectabilis fruit seed oil and oleum Lavandula Angustifolia to obtain mixture 1, heating water and humectant to obtain mixture 2, mixing mixture 1 and mixture 2, homogenizing, cooling to 30-60 deg.C, and adding acetyl chitosamine, radix Stephaniae Japonicae extract and nicotinamide adenine dinucleotide.
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CN110200876A (en) * 2019-07-12 2019-09-06 傅万金 It is a kind of to avenge tender maintenance essence dew formula and manufacture craft
CN112603867A (en) * 2021-01-04 2021-04-06 广东名兰化妆品制造有限公司 Skin membrane repairing essence stock solution and preparation method thereof
CN114557912A (en) * 2022-03-08 2022-05-31 广州市万千粉丝化妆品有限公司 Application of nicotinamide adenine dinucleotide reduced coenzyme I (NADH) in anti-aging cosmetics

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN105616283A (en) * 2015-12-30 2016-06-01 广州葆妍生物科技有限公司 Plant-essence restorative facial cream
CN105769666A (en) * 2016-03-18 2016-07-20 广州市索柔生物科技有限公司 Composition and skin care product containing same
CN106176347A (en) * 2016-07-13 2016-12-07 广州科玛生物科技股份有限公司 A kind of man moistens maintenance elite breast

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105616283A (en) * 2015-12-30 2016-06-01 广州葆妍生物科技有限公司 Plant-essence restorative facial cream
CN105769666A (en) * 2016-03-18 2016-07-20 广州市索柔生物科技有限公司 Composition and skin care product containing same
CN106176347A (en) * 2016-07-13 2016-12-07 广州科玛生物科技股份有限公司 A kind of man moistens maintenance elite breast

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