CN111643425B

CN111643425B - Pure natural plant oil control convergence composition, essence and preparation method thereof

Info

Publication number: CN111643425B
Application number: CN202010611368.7A
Authority: CN
Inventors: 龚德明; 徐洁琼; 容惠; 刘金玉
Original assignee: Guangzhou Jinan Cosmetics Co ltd
Current assignee: Guangzhou Jinan Cosmetics Co ltd
Priority date: 2020-06-29
Filing date: 2020-06-29
Publication date: 2023-01-06
Anticipated expiration: 2040-06-29
Also published as: CN111643425A

Abstract

The invention provides a pure natural plant oil-control convergence composition, essence and a preparation method thereof. The pure natural plant oil control astringent composition comprises: purslane extract, forsythia fruit extract, dried orange peel extract, rhizoma anemarrhenae root extract, laminaria saccharina extract and medicinal fomes fomentarius extract. The preparation raw materials of the essence comprise: the pure natural plant oil-control astringent composition, the humectant, the skin conditioner, the thickener and water. All components in the pure natural plant oil-control convergence composition are matched with each other, so that the composition has a synergistic effect, the oil control and pore convergence are combined into a whole, the large pores are converged while the oil is controlled, the problem of excessive oil secretion is reduced fundamentally, and the problem of greasy skin is radically solved; and the effect of reducing grease secretion from the source is realized by inhibiting 5 alpha-reductase, regulating sebum flow and quickly converging pores.

Description

Pure natural plant oil-control convergence composition, essence and preparation method thereof

Technical Field

The invention belongs to the technical field of cosmetics, and particularly relates to a pure natural plant oil control convergence composition, essence and a preparation method thereof.

Background

With the development and the updating of the concept of society, people pay more attention to the external appearance and physical maintenance. The demand of modern men on skin care products is increased year by year, the skin care products are diversified, the consumption tends to be rational, and the potential of men skin care product consumers is very huge. Unlike the skin care products for women which emphasize whitening, tenderness and smoothness, skin care products for men have special needs. The cuticle of the skin of men is thicker than that of women, the number of skin glands is larger and more developed, and the sebaceous glands and sweat glands are larger than those of women, so that the skin absorption capacity of men is poorer than that of women, the skin oil is more abundant than that of women, and 80 percent of men are oily or mixed with skin with partial oiliness. In addition, the pH value of the skin of the male is 4.5-6.0, which is lower than that of the female, and the acidity is higher than that of the female, so that the oil is more discharged from the face, pores are easier to be large, and the pore blockage phenomenon is easier to cause comedo and acne. In addition, because the stratum corneum is thicker in men's skin, once it is at an age where wrinkles are formed, it is generally deeper and wider than the wrinkles in women. Therefore, the development of corresponding skin care products aiming at the unique skin physiological characteristics of men is needed to meet the skin care requirements of men.

At present, relatively few skin care products which are independently researched and developed aiming at the skin characteristics of men in China are provided, the interaction among the components is relatively complex, or a large amount of mineral components and chemical components are often mixed, although the effect is good, the particles are too large, pores are easily blocked, and pox inflammation is caused. And the greasiness problem can not be fundamentally improved, most of the oil control products use charcoal, bamboo charcoal, starch and other components to achieve the effect of transient oil control through oil adsorption, and the oil control products lack inhibition on the source head oil glands, so that the greasiness of the skin can not be fundamentally improved, and the more the oil is removed, the larger the pores are. Skin greasiness problem is often accompanied with the problem of big pore, and both are cause and effect each other, but most oil control products are only concentrated on surface oil control, and the problem of big pore that leads to grease secretion is invisible or restraint is unfair, leads to the pore problem to obtain improving, and it is more serious to produce oil.

CN108852950A discloses an acne-removing cosmetic composition containing purslane extract and a preparation method thereof, wherein the composition comprises the following raw materials: purslane extract, mulberry leaf extract, pine needle essential oil, betaine, liquorice extract, loquat leaf extract, humectant, emulsifier, pH regulator, thickener and water. The composition has the effects of high efficiency, safety and antibacterial effect, can quickly kill skin parasitic flora such as propionibacterium acnes and mites, can prevent bacterial protomer from corroding to cause inflammation and acne growth, has the function of diminishing inflammation, can play a role in controlling oil, inhibits oil secretion and dredges hair follicles.

CN110882186A discloses a composition with oil control, pore shrinking and soothing functions and a preparation method thereof, which comprises the following components: medicinal fomes fomentarius extract, rosewood seed extract, chlorella extract, sophora flower bud extract, linseed extract, aesculus hippocastanum seed extract, marigold flower extract, glycerin, butylene glycol, water, phenoxyethanol, PEG-40 hydrogenated castor oil, sodium citrate, and citric acid. The composition with the functions of controlling oil, shrinking pores and relieving can obviously improve the problems of serious oil production of skin, large pores, fragile skin and the like.

Therefore, the composition with the oil control and convergence effects has important significance and wide market prospect in the field of cosmetics.

Disclosure of Invention

The invention aims to provide a pure natural plant oil-control convergence composition, essence and a preparation method thereof. The pure natural plant oil-control and astringency composition integrates double effects of controlling oil and astringing pores, and can astringe large pores while controlling oil, so that the problem of excessive secretion of oil is radically solved, and the problem of greasy skin is radically solved.

In order to achieve the purpose, the invention adopts the following technical scheme:

in a first aspect, the present invention provides an all natural plant oil control astringent composition, comprising: purslane extract, forsythia fruit extract, dried orange peel extract, rhizoma anemarrhenae root extract, laminaria saccharina extract and medicinal fomes fomentarius extract.

According to the invention, the purslane extract, the forsythia suspense fruit extract, the dried orange peel extract, the rhizoma anemarrhenae root extract, the laminaria saccharina extract and the medicinal fomes officinalis extract in the purely natural plant oil-control astringent composition are matched with each other, so that a synergistic effect is achieved, excessive skin keratinization is avoided by promoting peeling of waste cutin, grease secretion is inhibited, activity of pores is reduced, and water-oil balance of skin is maintained; and the effect of reducing grease secretion from the source is realized by inhibiting 5 alpha-reductase, regulating sebum flow and quickly converging three channels of pores. Thereby effectively balancing the pH value and the grease secretion of the skin, purifying pores, repairing damaged skin, effectively regulating diastolic pores, obviously converging coarse pores and enabling the skin to quickly present a fine, smooth and compact state.

The purslane extract contains plant polysaccharide and vitamins, can nourish and lubricate the skin, promote the physiological function of epithelial cells to be normal, reduce dead skin and cuticle production caused by dryness, relieve the skin and inhibit skin itch caused by dry skin, and can improve oily skin from multiple aspects and angles. The forsythia suspense fruit extract has a remarkable oil control effect, can inhibit excessive sebaceous gland secretion, prevent sebum from accumulating in hair follicles, and can remove various toxins in the hair follicles. The dried orange peel extract contains various active ingredients, flavonoid compounds, alkaloid, tannin, polysaccharide, various chemical ingredients such as trace elements necessary for human bodies and the like, and the ingredients have synergistic effect to change the differentiation process of sebaceous gland cells, so that the efficacy of inhibiting sebum secretion is achieved, the dried orange peel extract also has the effects of nourishing and lubricating skin, promoting the physiological function of epithelial cells to be normal, improving the water content of the skin and relieving dry skin. Timosaponin AIII in rhizoma anemarrhenae root extract has effects of inhibiting platelet aggregation, inhibiting abnormal secretion of sebaceous gland, inhibiting release of arachidonic acid induced inflammatory factor, promoting blood circulation, inhibiting excessive secretion of sebaceous gland, and relieving inflammation. Laminaria Saccharina extract belongs to brown algae extract, mainly contains glucuronide, can form a biological membrane with excellent moisturizing effect with protein in skin, can help skin to keep osmotic pressure balance, and can remarkably reduce sebum secretion by inhibiting lipase to regulate sebum flow. The medicinal fomes fomentarius extract is a pure concentrated active substance extracted from meat juice of basidiomycetes-griffonia simplicifolia growing in eastern europe. Can solve the problem of excessive secretion of skin oil, and has the effects of astringing, shrinking pores, keeping moisture, and smoothing and tightening skin.

Preferably, the pure natural plant oil control astringent composition comprises the following components in parts by weight: 1-10 parts of purslane extract, 1-10 parts of forsythia fruit extract, 1-10 parts of dried orange peel extract, 1-10 parts of rhizoma anemarrhenae root extract, 1-5 parts of laminaria saccharina extract and 1-5 parts of medicinal fomes fomentarius extract.

In the pure natural plant oil-control astringent composition, the purslane extract is contained in 1-10 parts, such as 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts and the like.

In the pure natural plant oil-control astringent composition, the content of the forsythia suspense fruit extract is 1-10 parts, and can be 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts and the like.

In the pure natural plant oil-control astringent composition, the content of the dried orange peel extract is 1-10 parts, such as 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts and the like.

In the pure natural plant oil-control astringent composition, the content of the rhizoma anemarrhenae extract is 1-10 parts, and can be 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts and the like.

In the pure natural plant oil-control astringent composition, the content of the laminaria saccharina extract is 1-5 parts, such as 1 part, 2 parts, 3 parts, 4 parts, 5 parts and the like.

In the pure natural plant oil-control astringent composition, the content of the fomes officinalis extract is 1-5 parts, such as 1 part, 2 parts, 3 parts, 4 parts, 5 parts and the like.

In a second aspect, the invention provides an essence, which is prepared from the following raw materials: the pure natural plant oil control astringent composition of the first aspect, a humectant, a thickener and water.

In the invention, the essence obtained by adding the pure natural plant oil-control astringent composition disclosed by the first aspect can help skin to continuously control oil, dredge pores, refine pores, remove acnes and smooth acnes, and obtain smooth and fine skin feel.

Preferably, the preparation raw materials of the essence comprise the following components in percentage by mass: the oil-controlling and astringing composition of the pure natural plant in the first aspect is 0.1-5%, the humectant is 5-15%, the thickener is 0.5-1%, and the balance is water.

The content of the pure natural plant oil-control astringent composition of the first aspect is 0.1-5%, for example, 0.1%, 0.2%, 0.4%, 0.6%, 0.8%, 1%, 2%, 3%, 4%, 5%, etc., based on 100% by mass of the raw materials for preparing the essence.

The content of the humectant is 5-15%, for example, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, etc., based on 100% by mass of the raw materials for preparing the essence.

The content of the thickener is 0.5-1%, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc., based on 100% by mass of the raw materials for preparing the essence.

Preferably, the humectant comprises any one or a combination of at least two of butylene glycol, hyaluronic acid, glycerol or betaine, preferably a combination of butylene glycol, hyaluronic acid, glycerol and betaine.

The sodium hyaluronate cross-linked polymer can enable water to enter intercellular spaces, and is combined with protein to form protein gel, so that cells are bonded, normal metabolism is exerted, and water of the cells is kept; the betaine can help skin to resist oxidative stimulation, chemical stimulation, physical injury and stimulation caused by a surfactant, and can promote the synthesis of collagen, keep moisture, tighten skin and improve elasticity. The two materials are matched with each other to have a synergistic effect, so that the horny layer can be softened, the histiocyte regeneration can be promoted, the skin can be tightened, and the skin barrier function can be enhanced by the good film-forming property of the skin-care cream, so that the water-oil balance can be controlled.

Preferably, the thickener is an acrylate/C10-30 alkanol acrylate crosspolymer and/or xanthan gum.

Wherein the acrylate/C10-30 alkyl acrylate crosslinked polymer (Acrylates/C10-30 alkyl acrylate crosslinker) is a crosslinked polymer obtained by polymerizing C10-30 alkyl acrylate and acrylic monomer.

Preferably, the raw materials for preparing the essence also comprise any one or a combination of at least two of a skin conditioner, a chelating agent, a preservative, a pH regulator, a solubilizer or a fragrance.

Preferably, the raw materials for preparing the essence also comprise 0.5-1% of skin conditioning agent, such as 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1% and the like.

Preferably, the skin conditioning agent is niacinamide.

Preferably, the raw materials for preparing the essence also comprise 0.05-0.5% of a chelating agent, such as 0.05%, 0.06%, 0.08%, 0.1%, 0.12%, 0.14%, 0.16%, 0.18%, 0.2%, 0.3%, 0.4%, 0.5% and the like.

Preferably, the chelating agent is disodium EDTA.

Preferably, the raw materials for preparing the essence also comprise 0.1-1% of preservative, such as 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1% and the like.

Preferably, the preservative is any one or a combination of at least two of methylparaben, ethylhexyl glycerol or phenoxyethanol.

Preferably, the raw materials for preparing the essence also comprise 0.2-0.5% of pH regulator, such as 0.2%, 0.3%, 0.4%, 0.5%, etc

Preferably, the pH adjusting agent is triethanolamine.

Preferably, the raw materials for preparing the essence also comprise 0.01-1% of solubilizer, such as 0.01%, 0.05%, 0.1, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1% and the like.

Preferably, the solubilizer is PEG-40 hydrogenated castor oil.

Preferably, the raw materials for preparing the essence also comprise 0.01-0.3% of aromatic, such as 0.01%, 0.02%, 0.04%, 0.06%, 0.08%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3% and the like.

Preferably, the fragrance is a perfume.

In a third aspect, the present invention provides a method for preparing the essence according to the second aspect, wherein the method for preparing the essence comprises the following steps:

(1) Mixing a humectant, a thickener and water to obtain a water phase mixed solution;

(2) And (2) mixing the water phase mixed liquor obtained in the step (1) with the pure natural plant oil-control convergence composition, and filtering to obtain the essence.

Preferably, the mixing temperature in step (1) is 80-85 deg.C, such as 80 deg.C, 81 deg.C, 82 deg.C, 83 deg.C, 84 deg.C, 85 deg.C, etc., and the mixing time is 5-10min, such as 5min, 6min, 7min, 8min, 9min, 10min.

Preferably, the mixing temperature in step (2) is 40-50 deg.C, such as 40 deg.C, 42 deg.C, 44 deg.C, 46 deg.C, 48 deg.C, 50 deg.C, etc., and the mixing time is 5-15min, such as 5min, 7min, 9min, 11min, 13min, 15min, etc.

Preferably, the filtration in step (2) is performed by using 100-300 mesh filter cloth, such as 100 mesh, 120 mesh, 140 mesh, 160 mesh, 180 mesh, 200 mesh, 220 mesh, 240 mesh, 260 mesh, 280 mesh, 300 mesh, etc.

Preferably, the preparation method of the essence comprises the following steps:

(1) Mixing humectant, thickener and water at 80-85 deg.C for 5-10min to obtain water phase mixed solution;

(2) Mixing the water phase mixed solution obtained in the step (1), the pure natural plant oil-controlling astringent composition and the rest of other components at 40-50 ℃ for 5-15min, and filtering with 100-300 mesh filter cloth to obtain the essence.

Wherein the rest other components are any one or combination of at least two of skin conditioner, chelating agent, antiseptic, pH regulator, solubilizer or aromatic.

Compared with the prior art, the invention has the following beneficial effects:

(1) The pure natural plant oil-control convergence composition has the advantages that the natural plant sources are adopted, no mineral particle component is added, the composition is friendly to skin, mild and free of burden, and the harm of pore blockage is avoided;

(2) All components in the pure natural plant oil-control convergence composition are matched with each other, so that the composition has a synergistic effect, the oil control and pore convergence are combined into a whole, the large pores are converged while the oil is controlled, the problem of excessive oil secretion is reduced fundamentally, and the problem of greasy skin is radically solved; the effect of reducing grease secretion from the source is realized by inhibiting 5 alpha-reductase, regulating sebum flow and rapidly converging three channels of pores;

(3) In the invention, the essence prepared by adding the pure natural plant oil-control convergence composition has an inhibition rate of more than 75% on 5 alpha-reducing enzyme liquid; the forehead skin oil is still maintained below 20% after 8 weeks by using the essence prepared from the pure natural plant oil-control convergence composition; after 8 weeks, the pH value of the forehead skin is maintained below 6.5 and is stabilized at the normal level of weak acid; the pore diameter of skin pores of 8 weeks later of the essence prepared from the pure natural plant oil-control convergence composition maintains below 150 microns.

Detailed Description

The technical solution of the present invention is further described below by way of specific embodiments. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as the specific limitations of the present invention.

Example 1

The embodiment provides a pure natural plant oil control convergence composition, which comprises the following components in parts by weight: 5 parts of purslane extract, 5 parts of forsythia fruit extract, 5 parts of dried orange peel extract, 5 parts of rhizoma anemarrhenae root extract, 3 parts of laminaria saccharina extract and 2 parts of medicinal fomes fomentarius extract.

Example 2

The embodiment provides a pure natural plant oil control convergence composition, which comprises the following components in parts by weight: 4 parts of purslane extract, 6 parts of forsythia fruit extract, 6 parts of dried orange peel extract, 4 parts of rhizoma anemarrhenae root extract, 2 parts of laminaria saccharina extract and 3 parts of medicinal fomes fomentarius extract.

Example 3

The embodiment provides a pure natural plant oil control convergence composition, which comprises the following components in parts by weight: 4.5 parts of purslane extract, 5 parts of forsythia fruit extract, 4.5 parts of dried orange peel extract, 3 parts of rhizoma anemarrhenae root extract, 4 parts of laminaria saccharina extract and 4 parts of medicinal fomes fomentarius extract.

Example 4

The embodiment provides a pure natural plant oil control convergence composition, which comprises the following components in parts by weight: 6 parts of purslane extract, 6 parts of forsythia fruit extract, 6 parts of dried orange peel extract, 5 parts of rhizoma anemarrhenae root extract, 1 part of laminaria saccharina extract and 1 part of medicinal fomes fomentarius extract.

Example 5

The embodiment provides a pure natural plant oil control convergence composition, which comprises the following components in parts by weight: 1 part of purslane extract, 1 part of forsythia fruit extract, 6 parts of dried orange peel extract, 5 parts of rhizoma anemarrhenae root extract, 6 parts of laminaria saccharina extract and 6 parts of medicinal fomes officinalis extract.

Comparative examples 1 to 6

Comparative examples 1-6 different purely natural vegetable oil-controlling astringent compositions were provided, respectively, in the formulations shown in table 1 below (in the table, "6" represents the corresponding component in an amount of 6 parts by weight):

TABLE 1

Application example 1

The application embodiment provides an essence, and the preparation raw materials of the essence comprise the following components in percentage by mass:

the preparation method of the essence comprises the following steps:

(1) Mixing humectant, thickener and water at 82 deg.C for 8min to obtain water phase mixed solution;

(2) And (2) mixing the water phase mixed solution obtained in the step (1), the oil-control astringent composition, the skin conditioner, the chelating agent, the preservative, the pH regulator, the solubilizer and the aromatic provided in the example 1 at 45 ℃ for 10min, and filtering by using a filter cloth of 200 meshes to obtain the essence.

Application example 2

The application example provides an essence, and the difference from the application example 1 is that the pure natural plant oil-control astringent composition provided by the example 1 is replaced by the pure natural plant oil-control astringent composition provided by the example 2, and the content of other components and the preparation method are the same as those of the application example 1.

Application example 3

The application example provides an essence, and the difference from the application example 1 is that the pure natural plant oil control convergence composition provided in the example 1 is replaced with the pure natural plant oil control convergence composition provided in the example 3, and the contents of other components and the preparation method are the same as those of the application example 1.

Application example 4

The application example provides an essence, and the difference from the application example 1 is that the pure natural plant oil-control astringent composition provided by the example 1 is replaced by the pure natural plant oil-control astringent composition provided by the example 4, and the content of other components and the preparation method are the same as those of the application example 1.

Application example 5

The application example provides an essence, and the difference from the application example 1 is that the pure natural plant oil-control astringent composition provided by the example 1 is replaced by the pure natural plant oil-control astringent composition provided by the example 5, and the content of other components and the preparation method are the same as those of the application example 1.

Application example 6

The application example provides an essence, and is different from the application example 1 in that the humectant does not contain hyaluronic acid, the betaine content is increased to 3%, and the content of other components and the preparation method are the same as those of the application example 1.

Application example 7

The application example provides an essence, and is different from the application example 1 in that the humectant does not contain betaine, the content of hyaluronic acid is increased to 3%, and the content of other components and the preparation method are the same as those in the application example 1.

Comparative examples 1 to 6 of application

The difference from the application example 1 is that the pure natural plant oil control astringent composition provided by the example 1 is respectively and correspondingly replaced by the pure natural plant oil control astringent compositions provided by the comparative examples 1 to 6, and the contents of other components and the preparation method are the same as the application example 1.

Application comparative example 7

The application comparative example provides essence, and is different from the application example 1 in that the essence does not contain a pure natural plant oil control convergence composition, water is used for supplementing the essence to 100%, and the contents of other components and the preparation method are the same as those of the application example 1.

Test example 1

Safety performance testing

The essence provided by the application examples 1 to 7 and the essence provided by the application comparative examples 1 to 7 were subjected to safety performance tests by the following methods:

(1) Haemolysis test of erythrocytes

Preparation of erythrocyte suspension: selecting healthy rabbit, taking 9mL of blood from heart, adding 1mL of 2% potassium oxalate solution, centrifuging, discarding supernatant, diluting the precipitate to 20mL with 20mmol/L PBS solution, and storing at 4 ℃ for later use. Select samples were diluted with PBS solution to different concentrations, with 5 concentration gradients set for each sample. Adding 200 μ L of the above erythrocyte suspension (final concentration of the sample is controlled to be 5, 10, 20, 50, 100mg/mL respectively) into 10mL of diluent of the sample to be tested, taking distilled water as total blood-dissolving control, taking PBS solution as negative control, mixing gently, incubating at 37 deg.C for 30min, centrifuging at 2000r/min for 10min, collecting supernatant, and testing its absorbance at 560nm with spectrophotometer (A) ₅₆₀ ) Calculating the hemolysis rate according to the following formula;

a standard curve of hemolysis rate vs. sample concentration was plotted, and the sample concentration at which hemolysis occurred in 50% erythrocytes (HD) was calculated ₅₀ )。

(2) Protein denaturation experiments:

diluting the sample to 10g/L with PBS solution, collecting 10mL dilution of the sample to be tested, adding 200 μ L of the erythrocyte suspension, using distilled water as blank control, 1mg/mL Sodium Dodecyl Sulfate (SDS) solution as positive control, mixing gently, incubating at 37 deg.C for 30min, centrifuging at 2000r/min for 10min, collecting supernatant, and testing absorbance A at 540nm and 575nm with spectrophotometer ₅₄₀ And A ₅₇₅ Calculating a protein Denaturation Index (DI) according to the following formula;

wherein R is ₁ = blank control group a ₅₇₅ Blank control group A ₅₄₀ ，R ₂ = Experimental group A ₅₇₅ Experimental group A ₅₄₀ ，R ₃ = positive control group a ₅₇₅ Positive control group A ₅₄₀ 。

Evaluating the irritation of the sample to be tested according to the L/D value, wherein the L/D value is HD ₅₀ DI, erythrocyte hemolysis assay irritation grading criteria are shown in Table 2 below:

TABLE 2

L/D	Grading
		>100	Has no irritation
10<L/D≤100	Micro-stimulation property
		1<L/D≤10	Mild irritation
0.1<L/D≤1	Moderate irritation

The results of the above-described hemolysis test and protein denaturation test are shown in Table 3 below:

TABLE 3

Test sample	HD ₅₀ (mg/L)	DI(％)	L/D	Evaluation of
					Application example 1	24870	1.50	>100	Has no irritation
Application example 2	25098	1.45	>100	Has no irritation
					Application example 3	24980	1.56	>100	Has no irritation
Application example 4	23080	1.65	>100	Has no irritation
					Application example 5	23391	1.70	>100	Has no irritation
Application example 6	22119	1.68	>100	Has no irritation
					Application example 7	22054	1.72	>100	Has no irritation
Application comparative example 1	17555	2.56	>100	Has no irritation
					Comparative application example 2	18748	2.27	>100	Has no irritation
Comparative application example 3	17483	2.39	>100	Has no irritation
					Comparative application example 4	17671	2.42	>100	Has no irritation
Comparative application example 5	18430	2.59	>100	Has no irritation
					Comparative application example 6	19470	2.50	>100	Has no irritation
Application comparative example 7	14020	3.97	>100	Has no irritation

As can be seen from the safety performance test, the essence prepared by the application examples 1-7 is mild and non-irritant according to the test results; the sample concentration HD of the essence prepared by the invention when 50% red blood cells are subjected to hemolysis ₅₀ Over 20000mg/L, is larger than HD of the essence prepared by the application of the comparative examples 1-7 ₅₀ Meanwhile, the protein denaturation index DI is below 2% and is obviously smaller than that of the essence prepared by the application comparative examples 1-6, which shows that the toxic and side effects and irritation of the essence can be obviously reduced by adding the pure natural plant oil-control astringent composition, and the essence is safer and more reliable.

Test example 2

Inhibition test of 5 alpha-reductase solution

Test samples: the essence provided by application examples 1-7 and the essence provided by application comparative examples 1-7;

subject: 7 male SD rat livers;

the experimental principle is as follows: sebaceous gland hyperactivity is mainly associated with imbalance of sex hormone secretion. Sebaceous glands are the target organs for androgens. Testosterone increases sebaceous gland volume and secretion. Especially, the 5 alpha-reductase is over-active in the human body endothelial fat synthesis catalyst, so that the secretion of the dihydrotestosterone is increased, and the sebaceous gland is promoted to be abnormally increased. Therefore, the skin of a male is more oily than that of a female, and pores are large, so that genetic factors exist. The mechanism of action of androgens: most of the circulating testosterone is bound to sex hormone binding protein, only 1-2% is free, and the part enters sebaceous gland cells to influence the functions of the testosterone. Dehydroepiandrosterone and androstenedione secreted by the adrenal glands, other androgens in the circulation, may also enter sebaceous gland cells and be converted into testosterone for action. Testosterone entering the sebaceous gland is converted into 5 alpha-dihydrotestosterone by intracellular 5 alpha-reductase, then is combined with steroid cells in cytoplasm, enters nucleus and is combined with chromatin. Through up-regulation, the sterol regulatory factor binding protein pathway is activated to influence DNA transcription, and the effects of promoting the proliferation, differentiation and secretion of sebaceous gland cells are achieved;

the experimental steps are as follows: 14 identical 5 alpha-reducing enzyme solutions are prepared by using liver homogenates of 7 male SD rats and divided into 14 groups, one of the composition samples is added into each group, and the inhibition rate of the oil control composition containing the oil control composition on the 5 alpha-reducing enzyme solution is detected through a series of reaction systems, wherein the higher the inhibition rate is, the better the oil control effect is.

The specific test results are shown in table 4 below:

TABLE 4

The test results in table 4 show that the essence prepared by adding the pure natural plant oil-control astringent composition has an inhibition rate of more than 75% on 5 alpha-reductase. Because excessive androgen can cause the volume of sebaceous glands to be increased and sebum secretion to be increased, the duct of the pilosebaceous glands has abnormal keratinization, sebum excretion is not smooth, and lipid embolism is formed, the purslane extract, the forsythia suspense fruit extract, the dried orange peel extract, the rhizoma anemarrhenae root extract, the laminaria saccharina extract and the medicinal fomes fomentarius extract in the purely natural plant oil-control convergence composition are matched with each other, have a synergistic effect, and can effectively inhibit androgen from being converted into dihydrotestosterone with stronger activity under the action of 5 alpha-reductase through inhibiting the 5 alpha-reductase, so that the problems of excessive sebum secretion, sebaceous gland hyperplasia and excessive keratinization of skin are effectively solved.

Test example 3

Skin oil content test

The experimental principle is as follows: the grease test is based on the photometer principle. A special extinction adhesive tape with the thickness of 0.1mm is selected, and grease on human skin can be rapidly absorbed. The extinction adhesive tape is changed into a semitransparent state under the action of the grease, the more the grease is absorbed, the greater the light transmission amount is, the light transmission amount is measured by a photometer, and the content of the skin grease can be measured according to the change of the light transmission amount before and after the extinction adhesive tape.

Testing an instrument: the curometer MPA580 grease test probe Sebumeter manufactured by Courage + Khazaka, germany (CK, germany).

The test method comprises the following steps: 140 volunteers, male men aged 20-50 years, were selected and randomly divided into 14 groups of 10 persons each, and each group was wiped on the forehead with the appropriate amount of the essence provided in application examples 1-7 and the essence provided in application comparative examples 1-7, and the technician used the skin oil test probe to test the test site 5 times, averaged, counted the measured values, and analyzed the skin oil secretion change rule and persistence by averaging.

The specific test results are shown in table 5:

TABLE 5

From the test results in table 5, it can be seen that the forehead skin oil and fat content is reduced to below 40% after 2 weeks, the forehead skin oil and fat content is reduced to below 30% after 4 weeks, and the forehead skin oil and fat content is still maintained below 20% after 8 weeks, and the oil and fat content does not relapse. The purslane extract, the forsythia fruit extract, the dried orange peel extract, the rhizoma anemarrhenae root extract, the laminaria saccharina extract and the medicinal fomes fomentarius extract in the pure natural plant oil-control convergence composition are matched with each other, have a synergistic effect, can effectively inhibit sebum secretion, regulate water-oil balance of skin and reduce sebaceous gland activity.

Test example 4

Determination of skin pH

The experimental principle is as follows: the pH of the skin is determined by water-soluble lipids in the stratum corneum, the perspiration and carbon dioxide. The skin surface is usually in a weak acidic state, the pH value is between 4.5 and 6.5, the skin can be protected from the bacterial damage only by keeping the normal weak acidic state of the skin, and when the skin grease is excessively secreted, the skin generally presents weak alkalinity, a large amount of bacteria are enriched on the skin surface, the skin presents an unhealthy state, and acne is easily formed.

The test method comprises the following steps: 140 volunteers, male men aged 20-50 years, were selected and randomly divided into 14 groups of 10 persons, each group was wiped on the forehead with appropriate amounts of the essence provided in application examples 1-7 and the essence provided in application examples 1-7, and skin oil and pH tests were performed every week, all tests were performed under constant temperature and humidity (temperature 20-22 ℃, relative humidity 10-60%).

The specific test results are shown in table 6:

TABLE 6

From the test results in table 6, it can be seen that the pH of the forehead skin decreases to below 7.0 after 2 weeks, the pH of the forehead skin decreases to below 6.5 after 4 weeks, and the pH of the forehead skin maintains below 6.5 after 8 weeks. The purslane extract, the forsythia fruit extract, the tangerine peel extract, the rhizoma anemarrhenae root extract, the laminaria saccharina extract and the fomes officinalis extract in the pure natural plant oil-control astringent composition are matched with each other, so that the synergistic effect is achieved, the oil secretion of the skin can be effectively inhibited, the pH value is stabilized at the normal level of weak acid, the skin is in the optimal state of absorbing nutrition, and the capacity of resisting external erosion, elasticity, luster, moisture and the like of the skin are in the optimal state.

Test example 5

Skin pore astringency assessment test

Testing the instrument: digimiC model 800 skin image analyser manufactured by Courage + Khazaka, germany, CK.

The test method comprises the following steps: 140 volunteers and men aged 20-50 are selected and randomly divided into 14 groups, 10 people in each group are selected, a proper amount of the essence provided in application examples 1-7 and the essence provided in application comparative examples 1-7 are respectively taken from each group to wipe facial skin, the pore aperture of skin is tested by a digimiC800 type skin image analyzer, the pore size of the same position is analyzed by shooting (amplifying by 20 times), a technician uses a probe to test the test part for 5 times, the average value is taken, the measured value is counted, and the average value method is used for evaluating the pore astringency effect of the cosmetic preparation.

The specific test results are shown in table 7:

TABLE 7

From the test results in table 7, it can be seen that the pore size of skin pores on the back surface of 2 weeks, the pore size of skin pores on the peripheral surface of 4 weeks and the pore size of skin pores on the peripheral surface of 8 weeks of the essence prepared by adding the all-natural plant oil-controlling astringent composition of the present invention are reduced to below 180 μm, and the pore size of skin pores on the peripheral surface of 4 weeks and the pore size of skin pores on the peripheral surface of 8 weeks are maintained to below 150 μm. The composition has the advantages that the six components, namely the purslane extract, the forsythia fruit extract, the dried orange peel extract, the rhizoma anemarrhenae root extract, the laminaria saccharina extract and the fomes officinalis extract, are matched with each other, so that the synergistic effect is realized, the oil control and the large pores are converged, the problem of excessive grease secretion is radically reduced, and the problem of greasy skin is radically improved.

The applicant states that the present invention is illustrated by the above examples to show the pure natural plant oil control astringent composition, essence and preparation method thereof, but the present invention is not limited to the above detailed method, i.e. it does not mean that the present invention must rely on the above detailed method to be implemented. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.

Claims

1. The pure natural plant oil control convergence composition is characterized by comprising the following components in parts by weight: 1-10 parts of purslane extract, 1-10 parts of forsythia suspense fruit extract, 1-10 parts of dried orange peel extract, 1-10 parts of rhizoma anemarrhenae root extract, 1-5 parts of laminaria saccharina extract and 1-5 parts of medicinal fomes fomentarius extract.

2. The essence is characterized by comprising the following preparation raw materials: the all natural plant oil control astringent composition of claim 1, humectant, thickener and water.

3. The essence according to claim 2, wherein the essence is prepared from the following raw materials in percentage by mass: the natural plant oil control astringent composition of claim 1, in an amount of 0.1-5%, humectant 5-15%, thickener 0.5-1%, and water in balance.

4. The essence of claim 2, wherein the moisturizer comprises any one or a combination of at least two of butylene glycol, hyaluronic acid, glycerol, or betaine.

5. The essence of claim 4 wherein the humectant is a combination of butylene glycol, hyaluronic acid, glycerin and betaine.

6. The essence of claim 2, wherein the thickener is an acrylate/C10-30 alkanol acrylate crosspolymer and/or xanthan gum.

7. The essence of claim 2, wherein the raw materials for preparing the essence further comprise any one or a combination of at least two of a skin conditioner, a chelating agent, a preservative, a pH regulator, a solubilizer or a fragrance.

8. The essence of claim 7, wherein the raw materials for preparing the essence further comprise 0.5-1% of a skin conditioner.

9. The serum of claim 7, wherein the skin conditioning agent is niacinamide.

10. The essence of claim 7, wherein the raw materials for preparing the essence further comprise 0.05-0.5% of a chelating agent.

11. The serum according to claim 7, characterized in that the chelating agent is disodium EDTA.

12. The essence of claim 7, wherein the raw materials for preparing the essence further comprise 0.1-1% of preservatives.

13. The essence of claim 7, wherein the preservative is any one or a combination of at least two of methylparaben, ethylhexyl glycerin and phenoxyethanol.

14. The essence of claim 7, wherein the raw materials for preparing the essence further comprise 0.2-0.5% of a pH regulator.

15. The essence of claim 7, wherein the pH regulator is triethanolamine.

16. The essence of claim 7, wherein the raw materials for preparing the essence further comprise 0.01-1% of a solubilizer.

17. The essence of claim 7, wherein the solubilizer is PEG-40 hydrogenated castor oil.

18. The essence of claim 7, wherein the raw materials for preparing the essence further comprise 0.01-0.3% of a fragrance.

19. The essence of claim 7, wherein the fragrance is a perfume.

20. The essence according to any one of claims 2-19, wherein the essence is prepared by the following steps:

(1) Mixing the humectant, the thickener and water to obtain a water phase mixed solution;

21. The method for preparing the essence of claim 20, wherein the mixing temperature of the step (1) is 80-85 ℃ and the mixing time is 5-10min.

22. The method for preparing the essence of claim 20, wherein the mixing temperature of the step (2) is 40-50 ℃ and the mixing time is 5-15min.

23. The essence of claim 20, wherein the filtration of step (2) is performed with 100-300 mesh filter cloth.

24. The essence according to claim 20, wherein the essence comprises the following steps: