CN110664729A

CN110664729A - Anti-aging composition, essence thereof and preparation method

Info

Publication number: CN110664729A
Application number: CN201911171428.1A
Authority: CN
Inventors: 孙胜
Original assignee: GUANGZHOU SHENGMEI COSMETIC CO Ltd
Current assignee: GUANGZHOU SHENGMEI COSMETIC CO Ltd
Priority date: 2019-11-26
Filing date: 2019-11-26
Publication date: 2020-01-10

Abstract

The invention relates to the technical field of cosmetics, in particular to an anti-aging composition, essence thereof and a preparation method thereof, wherein the composition comprises the following components: 0.1-1 part of yeast zinc, 0.1-1 part of American pear juice fermentation extract, 0.1-1 part of geranium wilfordii extract, 0.1-1 part of plantain seed extract, 0.05-0.2 part of myomyces, 0.1-0.5 part of lactoferrin, 1-3 parts of SkinBaby, 100.01-0.03 part of coenzyme Q, 0.01-0.03 part of pomegranate essence, 0.01-0.03 part of water-soluble lipoic acid, 0.1-0.3 part of water-soluble asiatic pennywort, 0.1-0.3 part of fresh coconut juice freeze-dried powder, 0.1-0.3 part of triethanolamine, 1-3 parts of silk peptide liquid and 0.05-0.1 part of menthyl lactate.

Description

Anti-aging composition, essence thereof and preparation method

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to an anti-aging composition, essence of the composition and a preparation method of the essence.

Background

With the development of science and technology, cosmetics become an indispensable article for people, and as for cosmetics, the cosmetics are prepared from various raw materials, and the cosmetic raw materials are divided into two categories of artificial synthetic raw materials and natural raw materials, wherein the artificial synthetic raw materials are more, and the synthetic raw materials are mostly chemical synthetic raw materials, so that the cosmetics cannot play a role in caring skin but can accelerate skin aging.

The skin is the largest organ covering the surface of the human body, and is very vulnerable to damage because of direct contact with the external environment and stimulation by various stressful factors such as oxidation, dryness and ultraviolet rays. Meanwhile, due to the influence of internal factors such as age, diet and living habits, the function of the skin is declined and the skin is genetically deformed, so that the skin is more easily aged. Because the skin is positioned at the outermost side of the human body, the beauty of the human body is clearly shown. Therefore, the anti-aging cosmetic becomes one of the products which are urgently needed by the vast female consumers.

Anti-aging cosmetics account for over 50% of the cosmetic market, and one of the most major factors of skin aging is skin photoaging caused by long-term exposure of the skin to ultraviolet radiation. Photo-aging of skin is caused by skin aging phenomena such as increase of free radicals in the skin, damage of biological membranes by the free radicals, promotion of increase and amorphization of elastin fibers, and significant decrease of collagen fibers and increase of glucosaminoglycans. Counteracting and scavenging free radicals prevents the damaging effects of free radicals, often through anti-oxidation.

Antioxidants currently fall into two categories: one class is the enzyme class of antioxidants, of which superoxide dismutase is the most widely used. However, such antioxidants have poor stability in cosmetics, and have a large molecular weight and cannot be absorbed, so that their use is limited; the other is a vitamin series non-enzyme antioxidant, such as vitamin A, vitamin E, vitamin C, coenzyme QlO, etc., but the antioxidant also has the phenomena of poor stability, easy color change, skin allergy induction, etc., so the use of the antioxidant is limited. At present, few skin care products with stable characteristics, excellent antioxidant effect and long-acting anti-aging effect in all aspects are available on the market. Therefore, the development of cosmetic raw materials with high safety level and good stability, which are derived from natural active ingredients of plants, has become a focus of attention of cosmetic research and development institutions and manufacturers in recent years. How to utilize the extraction of plant active ingredients to reasonably develop a novel formula containing the plant ingredients, avoid the irritation of a chemical synthetic preparation, further improve various effects of natural plant components such as aging resistance, oxidation resistance, stability and the like, and have important significance for the development of cosmetics.

Chinese patent CN105687093A discloses a natural anti-aging pomegranate skin care product and a preparation method thereof, belonging to the technical field of cosmetics. The skin care product is prepared from the following raw materials: red pomegranate pulp extract, red pomegranate rind aqueous extract, red pomegranate seed oil, red pomegranate flower essential oil, chlorella growth factor, red date polysaccharide, silk extract, angelica sinensis extract, phellodendron extract, liquorice extract, lily extract, rose hydrosol, tea plant hydrosol, sericin, water-soluble pearl powder, cocamidopropyl betaine, lauric monoglyceride and glacier water balance. The invention takes the extracts of pomegranate flowers, seeds, peels and pulp as main raw materials, and takes the natural components of liquorice, silk extract, chlorella extract and the like as auxiliary materials, can condition and repair the skin, effectively dispel dry and aged cutin on the surface of the skin, control excessive secretion of skin grease, have the functions of beautifying and beauty treatment, enhance the elasticity and vitality of the skin, deeply clean and moisten and have the anti-aging effect. However, the anti-aging effect and stability of the skin care product are to be further improved.

Chinese patent application CN109431909A discloses a cosmetic composition containing plant components, cosmetics, and a preparation method and application thereof. The cosmetic composition containing the plant components comprises the following components in parts by weight: balsam fruit oil, spinach leaf extract, macadamia oil, coriander seed oil, ecklonia cava extract, isatis root extract, American pear fruit extract and tangerine peel oil. The inventor of the invention researches and discovers that the composition prepared by mixing the balsam fruit oil, the spinach leaf extract, the macadamia blue cedar wood oil, the coriander seed oil, the ecklonia cava extract, the isatis root extract, the avocado extract and the tangerinega peel oil can play a synergistic whitening role of all the components, and when the composition is applied to cosmetics, the use amount of a chemically synthesized preparation with the whitening role can be obviously reduced, the whitening effect is good, the irritation is small, the composition is fresh and cool, does not stick to greasy, and the effects of diminishing inflammation, preserving moisture, scavenging free radicals and stabilizing and resisting oxidation are achieved. However, the antioxidant and irritation-reducing effects of the cosmetic are desired to be further improved.

Therefore, it is necessary to develop an anti-aging composition, essence thereof and a preparation method thereof, which can solve the above technical problems.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide the anti-aging composition with high stability, small irritation and remarkable anti-aging effect, the essence thereof and the preparation method.

The invention is realized by the following technical scheme:

an anti-aging composition comprises the following components: 0.1-1 part of yeast zinc, 0.1-1 part of American pear juice fermentation extract, 0.1-1 part of geranium wilfordii extract, 0.1-1 part of plantain seed extract, 0.05-0.2 part of myomyces, 0.1-0.5 part of lactoferrin, 1-3 parts of SkinBaby, 100.01-0.03 part of coenzyme Q, 0.01-0.03 part of pomegranate essence, 0.01-0.03 part of water-soluble lipoic acid, 0.1-0.3 part of water-soluble asiatic pennywort, 0.1-0.3 part of fresh coconut juice freeze-dried powder, 0.1-0.3 part of triethanolamine, 1-3 parts of silk peptide liquid and 0.05-0.1 part of menthyl lactate.

Preferably, the preparation method of the western pear juice fermentation extract comprises the following steps:

1) pulverizing avocado, adding zymophyte, fermenting, and filtering to obtain residue a and filtrate A;

2) adding the filter residue a into an organic solvent, performing microwave-assisted extraction, and filtering to obtain a filtrate B;

3) mixing the filtrate A and the filtrate B, sequentially extracting with ethyl acetate and dichloromethane, concentrating, and drying.

More preferably, the mass percentage of the zymophyte in the step 1) in the American pear is 5-10%.

More preferably, the fermentation bacteria in step 1) are lactobacillus acidophilus, lactobacillus plantarum and yeast.

More preferably, the viable bacteria ratio of the lactobacillus acidophilus, the lactobacillus plantarum and the yeast is 1-3:1-2: 1.

More preferably, the fermentation conditions in step 1) are 20-25 ℃ for 8-15 h.

More preferably, the step 1) includes the steps of: pulverizing fructus Pyri, adding 5-10% zymocyte (viable ratio of Lactobacillus acidophilus to Lactobacillus plantarum and yeast 1-3:1-2: 1), fermenting at 20-25 deg.C for 8-15 hr, and filtering to obtain residue a and filtrate A.

More preferably, the organic solvent in step 2) is a mixed solvent of methanol and ethanol.

More preferably, the volume ratio of methanol to ethanol is 1-3: 1.

More preferably, the step 2) includes the steps of: adding the filter residue a into an organic solvent, performing microwave-assisted extraction, repeating for 1-2 times, each time for 0.5-2h, and filtering to obtain filtrate B.

More preferably, the step 2) includes the steps of: adding the filter residue a into a mixed solvent of methanol and ethanol with the volume ratio of 1-3:1 of 2-4 times, performing microwave-assisted extraction with the microwave power of 100-.

Preferably, the composition also comprises 65-75 parts of water, 0.05-0.5 part of thickening agent, 10-30 parts of humectant and 0.1-1.5 parts of preservative.

More preferably, the thickener comprises at least one of transparent xanthan gum, carbomer U20.

More preferably, the thickener includes xanthan gum and carbomer U20.

More preferably, the thickener comprises transparent xanthan gum 0.05-0.2 parts, carbomer U200.1-0.3 parts.

More preferably, the humectant comprises at least one of glycerin, 1, 3-butylene glycol, polyglyceryl ether-10, and PEG-4000.

More preferably, the moisturizer comprises glycerin, 1, 3-butylene glycol, polyglyceryl ether-10, and PEG-4000.

More preferably, the humectant comprises 3-8 parts of glycerin, 5-10 parts of 1, 3-butanediol, 103-8 parts of polyglyceryl ether and 01-5 parts of PEG-40001.

More preferably, the preservative comprises at least one of phenoxyethanol, E-1008.

More preferably, the preservative comprises phenoxyethanol and E-1008.

More preferably, the preservative comprises 0.1-0.5 parts of phenoxyethanol and E-10080.5-1 parts.

More preferably, the composition comprises the following components: 65-75 parts of water, 0.05-0.2 part of transparent xanthan gum, 200.1-0.3 part of carbomer U, 3-8 parts of glycerol, 5-10 parts of 1, 3-butanediol, 103-8 parts of polyglycerol ether, 0.1-1 part of PEG-4005 parts of yeast zinc, 0.1-1 part of American pear juice fermentation extract, 0.1-1 part of geranium gracilis extract, 0.1-1 part of plantain seed extract, 0.05-0.2 part of myomyces, 0.1-0.5 part of lactoferrin, 1-3 parts of SkinBaby, 100.01-0.03 part of coenzyme Q, 0.01-0.03 part of red pomegranate essence, 0.01-0.03 part of water-soluble lipoic acid, 0.1-0.3 part of water-soluble asiatic pennywort, 0.1-0.3 part of fresh coconut 0.3 part of coconut, 0.1-0.3 part of TEA, 0.3 part of silk peptide, 1-3 parts of phenoxy liquid, 0.1-10080.5-1.26 parts of ethanol, 0.05-0.1 part of menthyl lactate.

The invention also relates to essence which comprises the composition.

The invention also relates to a preparation method of the composition, which comprises the following steps:

(1) mixing water with the fermented extract of the American pear juice, the extract of the geranium wilfordii and the extract of the plantain seeds to obtain a mixture 1;

(2) mixing the humectant with pomegranate essence, myo-beauty bacteria, skinnbaby, water-soluble asiatic pennywort herb, fresh coconut juice freeze-dried powder and silk peptide liquid to obtain a mixture 2;

(3) mixing yeast zinc, lactoferrin, coenzyme Q10, water-soluble lipoic acid, triethanolamine and menthyl lactate to obtain a mixture 3;

(4) mixing the mixture 1, the mixture 2 and the mixture 3, and adding a thickening agent and a preservative to obtain the water-based paint.

Preferably, the water in step (1) is heated to 40-60 ℃.

Preferably, the humectant water is heated to 30-40 ℃ in step (2).

More preferably, the preparation method comprises the following steps:

(1) heating water to 40-60 deg.C, mixing with the fermented extract of western pear juice, herba Erodii seu Geranii extract, and semen plantaginis extract to obtain mixture 1;

(2) heating the humectant to 30-40 deg.C, mixing with pomegranate essence, myo-beauty bacteria, SkinBaby, water soluble centella asiatica, fresh coconut juice lyophilized powder, and silk peptide solution to obtain mixture 2;

The invention has the beneficial effects that:

according to the invention, the type and proportion of zymophyte, fermentation temperature and other conditions in the fermentation process enable active ingredients obtained by fermenting the American pear juice fermentation extract in the preparation process to have a remarkable anti-aging effect, and the active ingredients are used together with other components, so that the American pear juice fermentation extract has no irritation to skin, and has a better anti-aging effect when being used together with other components.

According to the method, after the American pear juice is fermented, the filter residue is continuously extracted by using the mixed solvent of methanol and ethanol, so that the effective components can be fully extracted. In addition, the invention adopts ethyl acetate and dichloromethane for extraction in sequence, and the anti-aging effect of the active ingredients finally obtained by extraction is obvious through a specific extraction solvent and an extraction sequence.

The proportion of the raw materials in the invention is beneficial to the interaction of the components, promotes the anti-aging effect and finally obtains a product with higher stability.

The trace extract is added into the formula, so that the anti-aging effect is remarkable, and particularly, the synergy among the American pear juice fermentation extract, the geranium wilfordii extract and the plantain seed extract is remarkable.

In the preparation process of the anti-aging composition, the addition sequence and the mixing temperature of the raw materials are adopted, and particularly, the American pear juice fermentation extract, the geranium tenuifolium extract and the plantain seed extract are mixed at a certain temperature, so that the synergistic effect among the American pear juice fermentation extract, the geranium tenuifolium extract and the plantain seed extract is favorably exerted, and the anti-aging effect and the product stability are improved.

In the preparation process of the anti-aging composition, the thickener and the preservative are added finally, so that the stability of the finally obtained product is higher.

Detailed Description

The invention will be further described with reference to specific embodiments, and the advantages and features of the invention will become apparent as the description proceeds. These examples are illustrative only and do not limit the scope of the present invention in any way. It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention, and that such changes and modifications may be made without departing from the spirit and scope of the invention.

In examples 1-3 and comparative examples 1-6, yeast zinc was purchased from Angel Yeast Ltd;

the Geranium tenuifolium extract is purchased from Guanao Biotech limited of Hubei;

the psyllium seed extract is purchased from waters biotechnology, inc, langzhou;

mycosphaerella are purchased from Staphylococcus epidermidis, Inc., Yaya Biotechnology, Shanghai;

SkinBaby purchases of hyaluronic acid high-efficiency moisturizing stock solution from Youyuan brand of Guangzhou Huangrui science and technology GmbH;

the red pomegranate essence is purchased from fresh red pomegranate essence lotion of post-Korea cosmetics GmbH;

water-soluble centella asiatica was purchased from centella asiatica extract 20:1 from sienna biotech point;

the fresh coconut juice freeze-dried powder is purchased from Shaanxi Yanling natural biological products Co Ltd;

silk peptide liquid was purchased from Shenzhen Baisheng Fine chemical Co., Ltd.

Example 1

An anti-aging composition comprises the following components: 65 parts of water, 0.05 part of transparent xanthan gum, 10 parts of 1, 3-butanediol, 0.1 part of yeast zinc, 0.1 part of a western pear juice fermentation extract, 0.1 part of a fine geranium extract, 0.1 part of a plantain seed extract, 0.05 part of myo-beautifying bacteria, 0.1 part of lactoferrin, 1 part of SkinBaby, 100.01 parts of coenzyme Q, 0.01 part of red pomegranate essence, 0.01 part of water-soluble lipoic acid, 0.1 part of water-soluble centella asiatica, 0.1 part of fresh coconut juice freeze-dried powder, 0.1 part of triethanolamine, 1 part of a silk peptide solution, 0.1 part of phenoxyethanol and 0.05 part of menthyl lactate.

The preparation method of the American pear juice fermentation extract comprises the following steps:

1) pulverizing avocado, adding 5 wt% of zymocyte (viable ratio of Lactobacillus acidophilus to Lactobacillus plantarum to yeast 1:1: 1), fermenting at 20 deg.C for 8 hr, and filtering to obtain residue a and filtrate A;

2) adding the filter residue a into a mixed solvent of 2 times of methanol and 85% ethanol (the volume ratio of the methanol to the ethanol is 1:1), extracting for 0.5h with the assistance of microwave, wherein the microwave power is 100w, and filtering to obtain a filtrate B;

The preparation method of the composition comprises the following steps:

(1) heating water to 40 deg.C, mixing with the fermented extract of western pear juice, the extract of Geranium tenuifolium and the extract of semen plantaginis to obtain mixture 1;

(2) heating 1, 3-butanediol to 30 deg.C, mixing with punica granatum essence, Mycosphaerella reticulata, skinnbaby, water-soluble herba Centellae, fresh coconut juice lyophilized powder, and silk peptide solution to obtain mixture 2;

(4) mixing mixture 1, mixture 2 and mixture 3, and adding transparent xanthan gum and phenoxyethanol.

Example 2

An anti-aging composition comprises the following components: 75 parts of water, 0.2 part of transparent xanthan gum, 200.3 parts of carbomer U, 8 parts of glycerol, 10 parts of 1, 3-butanediol, 108 parts of polyglycerol ether, PEG-40005 parts, 1 part of zinc yeast, 1 part of a pear juice fermentation extract, 1 part of a geranium wilfordii extract, 1 part of a plantain seed extract, 0.2 part of myobeauty bacteria, 0.5 part of lactoferrin, 3 parts of SkinBaby, 100.03 parts of coenzyme Q, 0.03 part of pomegranate essence, 0.03 part of water-soluble lipoic acid, 0.3 part of water-soluble centella asiatica, 0.3 part of fresh coconut juice freeze-dried powder, 0.3 part of TEA, 3 parts of a silk peptide liquid, 0.5 part of phenoxyethanol, E-81 part of 100 parts of menthyl lactate.

1) pulverizing fructus Pyri, adding 10 wt% of zymocyte (viable ratio of Lactobacillus acidophilus to Lactobacillus plantarum to yeast of 3:2: 1), fermenting at 25 deg.C for 15 hr, and filtering to obtain residue a and filtrate A;

2) adding the filter residue a into a mixed solvent of 4 times of methanol and 95% ethanol (the volume ratio of methanol to ethanol is 3:1), performing microwave-assisted extraction with the microwave power of 300w, repeating for 2 times and 2 hours each time, and filtering to obtain filtrate B;

The preparation method of the composition comprises the following steps:

(1) heating water to 60 deg.C, mixing with the fermented extract of western pear juice, the extract of Geranium tenuifolium and the extract of semen plantaginis to obtain mixture 1;

(2) heating glycerol, 1, 3-butanediol, polyglyceryl ether-10 and PEG-4000 to 40 ℃, and mixing with pomegranate essence, myo-beauty bacteria, skinnbaby, water-soluble centella asiatica, fresh coconut juice freeze-dried powder and silk peptide liquid to obtain a mixture 2;

(4) mixing mixture 1, mixture 2 and mixture 3, and adding transparent xanthan gum, carbomer U20, phenoxyethanol and E-1008 to obtain the final product.

Example 3

An anti-aging composition comprises the following components: 70.53 parts of water, 0.1 part of transparent xanthan gum, 200.2 parts of carbomer U, 5 parts of glycerol, 8 parts of 1, 3-butanediol, 105 parts of polyglycerol ether, PEG-40003 parts, 0.5 part of yeast zinc, 0.5 part of a western pear juice fermentation extract, 0.5 part of a geranium wilfordii extract, 0.5 part of a plantain seed extract, 0.1 part of myotonin, 0.3 part of lactoferrin, 2 parts of SkinBaby, 100.02 parts of coenzyme Q, 0.02 part of pomegranate essence, 0.02 part of water-soluble lipoic acid, 0.2 part of water-soluble centella asiatica, 0.2 part of fresh coconut juice freeze-dried powder, 0.18 part of TEA, 2 parts of silk peptide liquid, 0.25 part of phenoxyethanol, E-10080.8 parts and 0.08 part of menthyl lactate.

1) pulverizing fructus Pyri, adding 8 wt% of zymocyte (viable ratio of Lactobacillus acidophilus to Lactobacillus plantarum to yeast 2:1.5: 1), fermenting at 23 deg.C for 11 hr, and filtering to obtain residue a and filtrate A;

2) adding the filter residue a into a mixed solvent of 3 times of methanol and 90% ethanol (the volume ratio of methanol to ethanol is 2:1), performing microwave-assisted extraction with microwave power of 200w, repeating for 1 time, each time for 1h, and filtering to obtain filtrate B;

The preparation method of the composition comprises the following steps:

(1) heating water to 50 deg.C, mixing with the fermented extract of western pear juice, the extract of Geranium tenuifolium and the extract of semen plantaginis to obtain mixture 1;

(2) heating glycerol, 1, 3-butanediol, polyglyceryl ether-10 and PEG-4000 to 35 ℃, and mixing with pomegranate essence, myo-beauty bacteria, skinnbaby, water-soluble centella asiatica, fresh coconut juice freeze-dried powder and silk peptide liquid to obtain a mixture 2;

Comparative example 1

The differences from the embodiment 3 are that the total dosage of the western pear juice fermented extract, the geranium tenuissima extract and the plantain seed extract is unchanged, but the dosage ratios of the three are changed, specifically 1.4 parts of the western pear juice fermented extract, 0.05 part of the geranium tenuissima extract and 0.05 part of the plantain seed extract, and the other conditions are the same.

Comparative example 2

The difference from the example 3 is only that in the preparation process of the American pear juice fermented extract, 8 wt% of fermentation bacteria are added in the step 1) and are lactobacillus acidophilus and lactobacillus plantarum, the ratio of the viable bacteria of the lactobacillus acidophilus to the lactobacillus plantarum is 2:1.5, and the rest conditions are the same.

Comparative example 3

The difference from example 3 is only that in the preparation process of the avocado juice fermentation extract, the filter residue a is added into 3 times of 90% ethanol solution in step 2), and the rest conditions are the same.

Comparative example 4

The difference from example 3 is only that in the preparation process of the American pear juice fermentation extract, step 3) adopts dichloromethane and ethyl acetate for extraction in sequence, and the rest conditions are the same.

Comparative example 5

The difference from the example 3 is only that in the preparation process of the composition, the adding sequence of the raw materials is different, and the rest conditions are the same, and are as follows:

(1) heating water to 50 deg.C, mixing with fermented extract of western pear juice, essence of pomegranate and lyophilized powder of fresh coconut juice to obtain mixture 1;

(2) heating transparent xanthan gum, carbomer U20, glycerol, 1, 3-butanediol, polyglyceryl ether-10 and PEG-4000 to 35 deg.C, mixing with herba Erodii seu Geranii extract, Mycoplasma, SkinBaby, water soluble herba Centellae, semen plantaginis extract and silk peptide solution to obtain mixture 2;

(4) mixing mixture 1, mixture 2 and mixture 3, and adding phenoxyethanol and E-1008 to obtain the final product.

Comparative example 6

The difference from example 3 is only that the temperature for mixing the raw materials is different during the preparation of the composition, and the other conditions are the same, specifically as follows:

(1) heating water to 30 deg.C, mixing with the fermented extract of western pear juice, the extract of Geranium tenuifolium and the extract of semen plantaginis to obtain mixture 1;

(2) heating glycerol, 1, 3-butanediol, polyglyceryl ether-10 and PEG-4000 to 60 ℃, and mixing with pomegranate essence, myo-beauty bacteria, skinnbaby, water-soluble centella asiatica, fresh coconut juice freeze-dried powder and silk peptide liquid to obtain a mixture 2;

Comparative example 7

The difference from the example 3 is only that the amount of each component is different, and the rest conditions are the same, which are as follows:

an anti-aging composition comprises the following components: 70.53 parts of water, 0.1 part of transparent xanthan gum, 200.2 parts of carbomer U, 5 parts of glycerol, 8 parts of 1, 3-butanediol, 105 parts of polyglycerol ether, PEG-40003 parts, 0.5 part of yeast zinc, 2 parts of a western pear juice fermentation extract, 0.05 part of a geranium wilfordii extract, 0.05 part of a plantain seed extract, 0.5 part of myobeauty bacteria, 0.3 part of lactoferrin, 2 parts of SkinBaby, 100.02 parts of coenzyme Q, 0.05 part of pomegranate essence, 0.02 part of water-soluble lipoic acid, 0.2 part of water-soluble centella asiatica, 0.01 part of fresh coconut juice freeze-dried powder, 0.18 part of TEA, 2 parts of silk peptide liquid, 0.25 part of phenoxyethanol, E-10080.8 parts and 0.08 part of menthyl lactate.

Test example 1

Examples 1-3 and comparative examples 1-7 were tested for stimulatory effects.

1. Test products: compositions obtained in examples 1 to 3 and comparative examples 1 to 7.

2. Number of test population: 100 persons, half each of male and female, age: between 18 and 45 years of age, health: the skin of the subject is healthy, has no allergic history of skin diseases, and meets the voluntary selection standard of the subject; grouping: 10 groups of 10 people each.

3. The spot pasting method comprises the following steps: selecting a qualified spot tester, dripping 0.020g-0.025g of a tested object into the spot tester in a closed spot patch test mode, externally applying a special adhesive tape to the back of the tested object, removing the tested object after 24 hours, observing skin reactions respectively at 0.5, 6, 12, 24 and 48 hours after removal, and recording the results according to the skin reaction grading standard in the cosmetic hygiene Specification.

4. The experimental results are as follows: the result of the human body skin patch test shows that: each group of subjects observed skin reactions at 0.5, 6, 12, 24, 48 hours by patch tests of the products of examples 1 to 3 and comparative examples 1 to 7, wherein 0 case showed adverse skin reactions, indicating that the cosmetic compositions prepared in examples 1 to 3 were mild, non-irritating, and good in anti-allergy effects.

Test example 2

The anti-aging effect of the products of examples 1-3 and comparative examples 1-7 was tested by randomly selecting 150 healthy volunteers aged 25-45 years, randomly dividing the volunteers into 10 groups of 15 people, and using the compositions prepared in examples 1-3 and comparative examples 1-7 of the present invention twice a day with 10ml each time after each face cleaning, and the time for each use was the same. After 1 month of continuous use, the anti-aging effect evaluation of the product by volunteers was collected, and the results are shown in table 1.

TABLE 1 EXAMPLES 1-3 AND COMPARATIVE EXAMPLES 1-7 ANTI-SKIN EFFECT TESTS

Test example 3

Examples 1-3 and comparative examples 1 and 5-7 were tested for product stability by allowing the product to stand for 2 months and observing the clarity of the product. The more precipitate, the worse the stability. The test results are shown in table 2.

TABLE 2 stability Effect test of examples 1-3 and comparative examples 1 and 5-7

	Clarity of the product
		Example 1	No precipitation
Example 2	No precipitation
		Example 3	No precipitation
Comparative example 1	There was little precipitation
		Comparative example 5	With a large amount of precipitate
Comparative example 6	There was little precipitation
		Comparative example 7	There was little precipitation

The above detailed description is specific to one possible embodiment of the present invention, and the embodiment is not intended to limit the scope of the present invention, and all equivalent implementations or modifications without departing from the scope of the present invention should be included in the technical scope of the present invention.

Claims

1. An anti-aging composition, which is characterized by comprising the following components: 0.1-1 part of yeast zinc, 0.1-1 part of American pear juice fermentation extract, 0.1-1 part of geranium wilfordii extract, 0.1-1 part of plantain seed extract, 0.05-0.2 part of myomyces, 0.1-0.5 part of lactoferrin, 1-3 parts of SkinBaby, 100.01-0.03 part of coenzyme Q, 0.01-0.03 part of pomegranate essence, 0.01-0.03 part of water-soluble lipoic acid, 0.1-0.3 part of water-soluble asiatic pennywort, 0.1-0.3 part of fresh coconut juice freeze-dried powder, 0.1-0.3 part of triethanolamine, 1-3 parts of silk peptide liquid and 0.05-0.1 part of menthyl lactate.

2. The composition according to claim 1, wherein the preparation method of the fermented extract of avocado juice comprises the following steps:

3. The composition of claim 2, wherein the amount of the zymophyte in step 1) is 5-10% by weight of the avocado; the zymocyte is lactobacillus acidophilus, lactobacillus plantarum and saccharomycetes, preferably, the viable bacteria ratio of the lactobacillus acidophilus, the lactobacillus plantarum and the saccharomycetes is 1-3:1-2: 1; the fermentation condition is fermentation at 20-25 deg.C for 8-15 h.

4. The composition according to claim 2, wherein the organic solvent in step 2) is a mixed solvent of methanol and ethanol, preferably in a volume ratio of 1-3: 1.

5. The composition according to claim 2, wherein the step 2) comprises the steps of: adding the filter residue a into an organic solvent, performing microwave-assisted extraction, repeating for 1-2 times, each time for 0.5-2h, and filtering to obtain filtrate B.

6. The composition of claim 1, further comprising 65-75 parts of water, 0.05-0.5 part of a thickener, 10-30 parts of a humectant, and 0.1-1.5 parts of a preservative.

7. The composition of claim 6, wherein the thickening agent comprises at least one of xanthan gum, carbomer U20; the humectant comprises at least one of glycerol, 1, 3-butanediol, polyglyceryl ether-10 and PEG-4000; the preservative comprises at least one of phenoxyethanol and E-1008.

8. A serum comprising the composition according to any one of claims 1 to 7.

9. A process for preparing a composition according to any one of claims 6 to 7, comprising the steps of:

10. The method of claim 9, comprising the steps of: