CN107822993A - A kind of anti-apolexis composition and the skin care item comprising said composition - Google Patents
A kind of anti-apolexis composition and the skin care item comprising said composition Download PDFInfo
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- CN107822993A CN107822993A CN201711272257.2A CN201711272257A CN107822993A CN 107822993 A CN107822993 A CN 107822993A CN 201711272257 A CN201711272257 A CN 201711272257A CN 107822993 A CN107822993 A CN 107822993A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of anti-apolexis composition, includes Radix Astragali leaf extract, Huai Goat, white willow bark extract.In anti-aging composition of the present invention, Radix Astragali leaf extract, Huai Goat, white willow bark extract are compounded, three's functional component is complementary, cost complementary, plays synergistic function jointly, not only has preferable anti-aging effect, and cost-effective；Coordinate dried apple slices cell extract, flue berry extract to be used together simultaneously, can further play synergistic function, reach more preferable anti-aging effects；Anti-aging effect is preferably nourished in long-term use, substantially playing for being grown from skin.Meanwhile invention additionally discloses a kind of skin care item for including the composition.
Description
Technical field
The present invention relates to a kind of composition, especially a kind of anti-apolexis composition and the skin care item comprising said composition.
Background technology
Skin aging is a progressive physiology course, and the various factors comprehensive function such as heredity, environment, social mentality
Result.As the improvement of people's living standards, the functional requirement more and more higher to skin care item, possesses the skin care of anti-aging effect
Product also emerge in an endless stream.Anti-aging approach, mainly includes：Protecting the skin from external environment stimulates, is in scavenger-cell unnecessary
Free radical, Skin Cell is repaired and supplemented the nutrients.Anti-aging skin is to prevent skin from occurring gradually because the time elapses
Property function sexually revise, show as preventing wrinkle, drying, play bits, relaxation and color spot.Anti-aging cosmetics are exactly to realize to prevent
One of the effect of cosmetics of aging effect are important type cosmetics.
The anti-aging current Yi Zhan cosmetics sales main market players of cosmetics, most of product is all main from skin senescence
Factor：Photo-aging and free radical are started with, and add such as superoxide dismutase (SOD), tocopherol acetate, Vitamin C
Acid, retinol, free radical is hindered to form peroxide, effect is relatively simple, while there is also stability is poor, easy to change and allergy
The problems such as.
Present anti-aging cosmetics some has used the strong industry of inoxidizability to reach good anti-aging effect
It is composition, quick in short-term, but it is very big using harm to the human body for a long time；The anti-aging cosmetics addition vitamins antioxygen having
Agent, but this kind of antioxidant stability is poor.By the natural plant extracts for having anti-aging effect be made stability it is good into
Divide and be added in cosmetics, assign product good anti-aging effect, be a trend of health care old product.
The content of the invention
Based on this, a kind of anti-aging combination is provided it is an object of the invention to overcome above-mentioned the deficiencies in the prior art part
Thing.
To achieve the above object, the technical solution used in the present invention is：A kind of anti-apolexis composition, is carried comprising Folium Astragali
Take thing, Huai Goat, white willow bark extract.
Present inventor has found that by Radix Astragali leaf extract, Huai Goat, white willow bark extract carries out cooperation makes
With, mutually promote, synergistic function can be played, reach preferable anti-aging effect, and it is cost-effective, wherein,
Radix Astragali leaf extract：Cell viability can be promoted, delay skin aging, strengthen cutaneous immunisation power, there is anti-inflammation and sterilization work
With；It is splendid cosmetics and skincare product with the function such as prevention and maintenance dermatitis, acne, facial defect, flat wart, scaly dry skin.
Huai Goat：Containing substantial amounts of ceramide, stratum corneum thickness can be increased, improve the specific retention of skin
Power, wrinkle is reduced, increase skin elasticity, anti-aging.
White willow bark extract：In cosmetics industry, white willow bark is counted as a kind of natural salicylic acid source.It is beautiful
State's research Dermatology meeting (Washington 1996:Bennet, Scholz, et al.) to report, white willow bark can provide salicylic acid, have
There is exfoliating, antibacterial, but not produce any related stimulate the reaction, epidermal cell vigor can also be strengthened, promote
Histocyte updates, and improves skin immunity, and prevention scytitis and the extraneous bacterium of resistance corrode, repair impaired skin, make dark
Dark rough skin reproduces honorable delicate.
Preferably, described anti-apolexis composition, the composition of following parts by weight is also included：5~10 parts of Radix Astragali leaf extract,
10~15 parts of Huai Goat, 5~10 parts of white willow bark extract.
It is highly preferred that the weight ratio of the Radix Astragali leaf extract, Huai Goat, white willow bark extract is：Folium Astragali
Extract：Huai Goat：White willow bark extract=(5~10):12：9.
Above-mentioned weight than three kinds of compositions, can further play synergistic function, reach preferable anti-aging effects.
It is highly preferred that the weight ratio of the Radix Astragali leaf extract, Huai Goat, white willow bark extract is：Folium Astragali
Extract：Huai Goat：White willow bark extract=5：12：9.
Above-mentioned weight than three kinds of compositions, can further play synergistic function, reach more preferable anti-aging effects.
Preferably, described anti-apolexis composition, also the dried apple slices cell extract comprising 3~5 parts by weight.
The active component that dried apple slices cell extract contains, the metabolism at cuticula and skin interval can be promoted, allowed
Skin cell irradiating new life, the effect of showing excellent anti-aging, while the more preferable hair of other compositions functional component can be promoted
Wave.
It is highly preferred that described anti-apolexis composition, also the flue berry extract comprising 5~10 parts by weight.
Containing abundant vitamin E and a kind of more special composition --- anthocyanidin in flue berry extract, have non-
Often good anti-oxidant, Green Tea Extract, anti-aging effect.
It is highly preferred that the weight ratio of the Radix Astragali leaf extract, dried apple slices cell extract, flue berry extract is：It is yellow
Stilbene leaf extract：Dried apple slices cell extract：Flue berry extract=(5~10)：4：7.
Above-mentioned weight than three kinds of compositions, can further play synergistic function, reach preferable anti-aging effects.
It is highly preferred that the weight ratio of the Radix Astragali leaf extract, dried apple slices cell extract, flue berry extract is：It is yellow
Stilbene leaf extract：Dried apple slices cell extract：Flue berry extract=6：4：7.
Above-mentioned weight than three kinds of compositions, can further play synergistic function, reach more preferable anti-aging effects.
Meanwhile the present invention also provides a kind of skin care item for including the composition.The skin care item have preferably anti-ageing
Old effect.
Preferably, weight/mass percentage composition of the composition in the skin care item is 8~15%.
In addition, it is noted that skin care item of the present invention can also include auxiliary material, the selection of auxiliary material has no tool herein
Body limits, and those skilled in the art can carry out conventional selection such as water, alcohols, finish, surfactant, pH according to being actually needed
The auxiliary materials such as conditioning agent, antioxidant or preservative.In addition, skin care item of the present invention can be made creme, emulsion, essence lotion,
The diversified forms such as gel or facial mask, the present invention have no specific restriction to this, and those skilled in the art can also be according to actual need
Carry out conventional selection.
Relative to prior art, beneficial effects of the present invention are：
In anti-aging skin care item of the present invention, Radix Astragali leaf extract, Huai Goat, white willow bark extract are answered
To match somebody with somebody, three's functional component is complementary, cost complementary, plays synergistic function jointly, not only has preferable anti-aging effect, and
It is and cost-effective；Coordinate dried apple slices cell extract, flue berry extract to be used together simultaneously, can further play collaboration and increase
Effect acts on, and reaches more preferable anti-aging effects；Long-term use, can from skin grow substantially play preferably nourish it is anti-aging
Effect.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.Skin care item described in the embodiment of the present invention can also include auxiliary material, and auxiliary material selection has no specific restriction herein, this
Art personnel can carry out conventional selection such as water, alcohols, finish, surfactant, pH adjusting agent, anti-according to being actually needed
The auxiliary material such as oxidant or preservative, in addition, the skin care item in embodiment are analyzed its performance only by taking Essence as an example, but not
Limitation and this, the compliance test result of other such as skin care item of creme, emulsion, gel or facial mask diversified forms is similarly.
7 kinds of embodiments of anti-aging composition of the present invention, with weight ratio meter, anti-aging group described in embodiment 1~7
The composition and content of compound are as shown in table 1：
Composition and content in the embodiment 1~7 of table 1 in anti-apolexis composition
Skin care item are made in composition in above-described embodiment 1~7, the skin care item are Essence, and the Essence also wraps
Composition containing following weight/mass percentage composition：Propane diols 4%, butanediol 3%, hydrolysis Jojoba esters 0.5%, Sodium Hyaluronate
0.03%th, essence and preservative, appropriate amount of water.
Embodiment 8
Antioxidant effect is tested
Theoretical according to free radical injury, the generation of free radical is to cause skin aging main cause.Therefore, if there is energy
The ability for removing free radical is one of important indicator for evaluating anti-aging skin care product.
DPPH.free radical (DPPH) is a kind of free radical centered on nitrogen of stabilization, if tested material can be clear
Except it, then it represents that tested material has the function that to reduce the free radicals such as hydroxy radical, alkane free radical or peroxy radical.DPPH exists
520nm has strong absorption, and its ethanol water is dark purple, and after adding tested material, in 520nm, using spectrophotometric determination, its is clear
Cause the situation of absorbance reduction except DPPH, tested material removing DPPH ability can be drawn according to absorbance change.Other are clear
Except the experimental principle of superoxide anion, hydroxy radical is same as above.
Detecting instrument：DPPH (Tokyo is melted into Co., Ltd., and analysis is pure)；UV-1600 ultraviolet specrophotometers
(METTLETOLEDO)。
Detection method：With dimethyl sulfoxide (DMSO) respectively by the sample preparation of previous embodiment into concentration be mass volume ratio 1%
Concentration, carry out following experiment.
The measure of radicals scavenging effect：(1) the diphenyl picryl benzene of sample solution 2ml and concentration for 100u mol/L is taken
Jing ﹙ DPPH ﹚ solution (solvent of the solution is for water) 2ml is first added in same tool plug test tube, shaken up, and stands 30 points at room temperature
Clock, using solvent as blank, the determination sample absorbance under 517nm wavelength.
Inhibiting rate：K%=[1-(Ai-Aj)/AC] × 100%, Ai：The extinction of 2ml DPPH solution+2ml sample solutions
Degree, Aj：The absorbance of 2ml sample solution+2ml solvents (i.e. dimethyl sulfoxide (DMSO)), AC：2ml DPPH solution+2ml solvents (i.e. two
Methyl sulfoxide) absorbance.Embodiment 1~7 is set to experimental group 1~7 respectively；The measurement result of specific radicals scavenging effect
Such as table 2.
The measurement result of the skin care item radicals scavenging of 2 embodiment of table 1~7 effect
From table 2 it can be seen that the removing free radical effect of the skin care item in embodiment 1 is better than the effect in embodiment 2~3
Fruit, the removing free radical effect in embodiment 1~3 are better than the effect of skin care item in embodiment 4~7, and this is also shield of the present invention
The preferred Radix Astragali leaf extract of skin product：Huai Goat：White willow bark extract=(5~10):12：9th, Radix Astragali leaf extract：Apple
Dried fruit cell extract：Flue berry extract=(5~10)：4：7, and further preferably Radix Astragali leaf extract：Huai Goat：
White willow bark extract=5：12：9th, Radix Astragali leaf extract：Dried apple slices cell extract：Flue berry extract=6：4：7 original
Cause.
Embodiment 9
Strengthen skin elasticity compliance test result
Subject Population is divided into 7 groups, every group of 20 people, the tested objective packet of crowd, and it is ignorant to product composition, exclude
Influence of the psychological factor to the product overall evaluation.Each group of people uses the skin-protection product of embodiment 1~7 respectively.Before sample is smeared, by
Examination person is using the gentle cleaning agent cleaning face of identical, and symmetric position selectes about 5 × 5cm at left and right sides of subject face2Greatly
The skin-protection product that about 0.5g each groups accordingly use is smeared, frequency of use is once in the morning and once at night, even as Experimental Area in small region
It is continuous to use daily.
Before skin-protection product using embodiment 1~7, in every subject's test zone Callegari softplus
The each experiment position initial elasticity m of spring probe detection of skinanalysis apparatus0Value, is repeated 5 times, draws average value respectively.Make
With being detected respectively again at these positions after 2,4,6 weeks, each test zone respectively 5 hypoelasticity m values of detection, and obtain the period 5
Secondary m average value.
In order to preferably evaluate the data obtained, the m detected every time respectively divided by is not used the m of sample0Averagely it is worth to
The elasticity grading at the position, when elastic grading value is bigger, illustrate that sample increase skin elasticity is more obvious.Use embodiment 1~7
The elasticity grading of product is as shown in table 3.
The elasticity grading of the product of 3 embodiment of table 1~7
From table 3 it can be seen that using after 6 weeks, it is higher than embodiment 2 using the elasticity grading of the skin care item in embodiment 1
Elasticity grading in~3, the elasticity that skin care item in embodiment 4~7 are higher than using the elasticity grading in embodiment 1~3 are graded,
There is identical rule with the data in table 2.
Embodiment 10
Experiment is divided into control group and experimental group, and experimental group 1~7 is respectively prepared skin care item in embodiment 1~7, is compareed
Component is 6 groups, and contained component is removed Radix Astragali leaf extract, Huai Goat, white willow bark and carried in the skin care item of control group 1~6
Taking outside the weight ratio difference of three kinds of compositions of thing, other compositions are same as Example 1, in addition, in every group of experiment, Folium Astragali extraction
The total content of thing, Huai Goat, white willow bark extract three in skin care item is identical, and simply the ratio of three is not
Together, in specific control group 1~6 three kinds of Radix Astragali leaf extract, Huai Goat, white willow bark extract compositions parts by weight such as table
Shown in 4：
Radix Astragali leaf extract, Huai Goat, the weight of three kinds of compositions of white willow bark extract in the control group skin care item of table 4
Part
| Group | 1 | 2 | 3 | 4 | 5 | 6 |
| Radix Astragali leaf extract | 5 | 0 | 0 | 0 | 5 | 5 |
| Huai Goat | 0 | 12 | 0 | 12 | 12 | 0 |
| White willow bark extract | 0 | 0 | 9 | 9 | 9 |
In control group and experimental group, choose 100 ages for every group and carry out research on probation in the volunteer of 20~50 years old, it is real
Test the skin care item that the subjects of group 1~7 are prepared using embodiment 1~7 respectively, the subjects difference of control group 1~6
The skin care item being prepared using control group 1~6, skin care item application method as in embodiment 9, if after 6 weeks, measure bullet
Property grading be higher than 1.60, be considered as effectively, statistics is efficient, as a result as shown in table 5.
The effective situation statistical result of anti-aging in the experimental group of table 5 and control group
As seen from Table 5, Radix Astragali leaf extract, Huai Goat, white willow are comprised only in the skin care item of control group 1~6
One kind in three kinds of compositions of bark extract, two kinds, without good anti-oxidant, anti-aging effects.And the shield of experimental group 1~7
Skin product contain three kinds of compositions, have good anti-oxidant, anti-aging effects.Thus it is provable, in skin care item of the invention, the Radix Astragali
Three kinds of leaf extract, Huai Goat, white willow bark extract compositions have the function that to mutually promote, mutually cooperateed with, Neng Gouqi
To significant anti-oxidant, anti-aging effects.
Embodiment 11
Experiment is divided into control group and experimental group, and experimental group 1~7 is respectively prepared skin care item in embodiment 1~7, is compareed
Component is 6 groups, and contained component is except Radix Astragali leaf extract, dried apple slices cell extract, flue in the skin care item of control group 1~6
The weight of three kinds of compositions of berry extract is outer than different, and other compositions are same as Example 1, in addition, in every group of experiment, Folium Astragali
The total content of extract, dried apple slices cell extract, flue berry extract three in skin care item is identical, simply three
Ratio is different, three kinds of Radix Astragali leaf extract in specific control group 1~6, dried apple slices cell extract, flue berry extract compositions
Parts by weight are as shown in table 6：
Three kinds of Radix Astragali leaf extract in the control group skin care item of table 6, dried apple slices cell extract, flue berry extract compositions
Parts by weight
In control group and experimental group, choose 100 ages for every group and carry out research on probation in the volunteer of 20~50 years old, it is real
Test the skin care item that the subjects of group 1~7 are prepared using embodiment 1~7 respectively, the subjects difference of control group 1~6
The skin care item being prepared using control group 1~6, skin care item application method as in embodiment 9, if after 6 weeks, measure bullet
Property grading be higher than 1.60, be considered as effectively, statistics is efficient, as a result as shown in table 7.
The effective situation statistical result of anti-aging in the experimental group of table 7 and control group
| Group | Efficiently individual quantity | It is efficient |
| Control group 1 | 5 | 5% |
| Control group 2 | 4 | 4% |
| Control group 3 | 8 | 8% |
| Control group 4 | 25 | 25% |
| Control group 5 | 27 | 27% |
| Control group 6 | 15 | 15% |
| Experimental group 1 | 78 | 78% |
| Experimental group 2 | 66 | 66% |
| Experimental group 3 | 65 | 65% |
| Experimental group 4 | 53 | 53% |
| Experimental group 5 | 49 | 49% |
| Experimental group 6 | 54 | 54% |
| Experimental group 7 | 51 | 51% |
As seen from Table 7, comprised only in the skin care item of control group 1~6 Radix Astragali leaf extract, dried apple slices cell extract,
One kind in three kinds of compositions of flue berry extract, two kinds, without good anti-oxidant, anti-aging effects.And experimental group 1~7
Skin care item contain three kinds of compositions, there are good anti-oxidant, anti-aging effects.Thus it is provable, in skin care item of the invention,
Three kinds of Radix Astragali leaf extract, dried apple slices cell extract, flue berry extract compositions have the work mutually promoted, mutually cooperateed with
With significant anti-oxidant, anti-aging effects can be played.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected
The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should
Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention
And scope.
Claims (10)
1. a kind of anti-apolexis composition, it is characterised in that include Radix Astragali leaf extract, Huai Goat, white willow bark extract.
2. anti-apolexis composition as claimed in claim 1, it is characterised in that also include the composition of following parts by weight：Folium Astragali
5~10 parts of extract, 10~15 parts of Huai Goat, 5~10 parts of white willow bark extract.
3. anti-apolexis composition as claimed in claim 1 or 2, it is characterised in that the Radix Astragali leaf extract, sophora bud extraction
Thing, the weight ratio of white willow bark extract are：Radix Astragali leaf extract：Huai Goat：White willow bark extract=(5~10):
12：9.
4. anti-apolexis composition as claimed in claim 3, it is characterised in that the Radix Astragali leaf extract, Huai Goat, white
The weight ratio of extract of willow bark is：Radix Astragali leaf extract：Huai Goat：White willow bark extract=5：12：9.
5. anti-apolexis composition as claimed in claim 1 or 2, it is characterised in that the dried apple slices also comprising 3~5 parts by weight is thin
Born of the same parents' extract.
6. anti-apolexis composition as claimed in claim 6, it is characterised in that the dragon fruit extraction also comprising 5~10 parts by weight
Thing.
7. anti-apolexis composition as claimed in claim 6, it is characterised in that the Radix Astragali leaf extract, apple stem cell carry
The weight ratio for taking thing, flue berry extract is：Radix Astragali leaf extract：Dried apple slices cell extract：Flue berry extract=(5~
10)：4：7.
8. anti-apolexis composition as claimed in claim 7, it is characterised in that the Radix Astragali leaf extract, apple stem cell carry
The weight ratio for taking thing, flue berry extract is：Radix Astragali leaf extract：Dried apple slices cell extract：Flue berry extract=6：4：
7。
A kind of 9. skin care item for including the composition as described in any one of claim 1~8.
10. skin care item as claimed in claim 9, it is characterised in that quality percentage of the composition in the skin care item
Content is 8~15%.
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| CN201711272257.2A CN107822993A (en) | 2017-12-05 | 2017-12-05 | A kind of anti-apolexis composition and the skin care item comprising said composition |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109364008A (en) * | 2018-12-05 | 2019-02-22 | 广州蔻赛生物科技有限公司 | A kind of multiple-effect moisturiser and preparation method thereof |
| CN111686048A (en) * | 2020-07-10 | 2020-09-22 | 广州市胜梅化妆品有限公司 | Anti-aging essence and preparation method thereof |
| CN114365845A (en) * | 2022-02-18 | 2022-04-19 | 吉林大学 | Plant fermentation composition and preparation method and application thereof |
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| CN107362094A (en) * | 2017-08-22 | 2017-11-21 | 房小华 | Plant beauty stoste and preparation method thereof |
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- 2017-12-05 CN CN201711272257.2A patent/CN107822993A/en not_active Withdrawn
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| CN107362094A (en) * | 2017-08-22 | 2017-11-21 | 房小华 | Plant beauty stoste and preparation method thereof |
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| 王建新等: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109364008A (en) * | 2018-12-05 | 2019-02-22 | 广州蔻赛生物科技有限公司 | A kind of multiple-effect moisturiser and preparation method thereof |
| CN111686048A (en) * | 2020-07-10 | 2020-09-22 | 广州市胜梅化妆品有限公司 | Anti-aging essence and preparation method thereof |
| CN114365845A (en) * | 2022-02-18 | 2022-04-19 | 吉林大学 | Plant fermentation composition and preparation method and application thereof |
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Application publication date: 20180323 |