CN107811909A - A kind of anti-aging composition and the skin care item containing said composition - Google Patents

A kind of anti-aging composition and the skin care item containing said composition Download PDF

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Publication number
CN107811909A
CN107811909A CN201711055450.0A CN201711055450A CN107811909A CN 107811909 A CN107811909 A CN 107811909A CN 201711055450 A CN201711055450 A CN 201711055450A CN 107811909 A CN107811909 A CN 107811909A
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China
Prior art keywords
extract
cordyceps
composition
aging
breast
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CN201711055450.0A
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Inventor
葛啸虎
陈海佳
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Priority to CN201711055450.0A priority Critical patent/CN107811909A/en
Publication of CN107811909A publication Critical patent/CN107811909A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of anti-aging composition, the composition of following parts by weight is included:2~6 parts of Cordyceps extract, wooden 10~15 parts of the berry extract of breast, 8~17 parts of gadol extract.In anti-aging composition of the present invention, Cordyceps extract, the wooden berry extract of breast, gadol extract are used in mixed way, one side three can play synergistic function jointly, reach more preferable anti-aging moist effect, on the other hand, the wooden berry extract of breast, gadol extract can further promote skin to fully absorb functional component in Cordyceps extract, more preferably more fully play its nursing role to skin, further reach more preferable anti-aging effect;Composition of the present invention is applied in skin care item, can be long-term use of, anti-aging effect is preferably nourished in substantially playing for being grown from skin.

Description

A kind of anti-aging composition and the skin care item containing said composition
Technical field
A kind of skin care item the present invention relates to composition and containing said composition, especially a kind of anti-aging composition and contain There are the skin care item of said composition.
Background technology
Skin aging is a progressive physiology course, and the various factors comprehensive function such as heredity, environment, social mentality Result.As the improvement of people's living standards, the functional requirement more and more higher to skin care item, possesses the skin care of anti-aging effect Product also emerge in an endless stream.Anti-aging approach, mainly includes:Protecting the skin from external environment stimulates, is in scavenger-cell unnecessary Free radical, Skin Cell is repaired and supplemented the nutrients.Anti-aging skin is to prevent skin from occurring gradually because the time elapses Property function sexually revise, show as preventing wrinkle, drying, play bits, relaxation and color spot.Anti-aging cosmetics are exactly to realize to prevent One of the effect of cosmetics of aging effect are important type cosmetics.
The anti-aging current Yi Zhan cosmetics sales main market players of cosmetics, most of product is all main from skin senescence Factor:Photo-aging and free radical are started with, and add such as superoxide dismutase (SOD), tocopherol acetate, Vitamin C Acid, retinol, free radical is hindered to form peroxide, effect is relatively simple, while there is also stability is poor, easy to change and allergy The problems such as.
Present anti-aging cosmetics some has used the strong industry of inoxidizability to reach good anti-aging effect It is composition, quick in short-term, but it is very big using harm to the human body for a long time;The anti-aging cosmetics addition vitamins antioxygen having Agent, but this kind of antioxidant stability is poor.By the natural plant extracts for having anti-aging effect be made stability it is good into Divide and be added in cosmetics, assign product good anti-aging effect, be a trend of health care old product.
The content of the invention
Based on this, a kind of anti-aging combination is provided it is an object of the invention to overcome above-mentioned the deficiencies in the prior art part Thing.
To achieve the above object, the technical solution used in the present invention is:A kind of anti-aging composition, includes following weight The composition of part:2~6 parts of Cordyceps extract, wooden 10~15 parts of the berry extract of breast, 8~17 parts of gadol extract.
Present inventor has found, by Cordyceps extract, the wooden berry extract of breast, gadol extract carries out cooperation makes With, mutually promote, synergistic function can be played, reach preferable anti-aging effect, wherein,
Cordyceps extract:Containing the anti-aging composition of multiple activities, elasticity of skin is improved, is shone bright anti-aging, moistens and protects It is wet, make skin net from inside to outside white penetrating, skin oxygen content can also be increased, active cell active absorption moisture, improve skin quality Dry, it is coarse etc. it is a series of because water shortage produce the problem of.
The wooden berry extract of breast:Sponifiable material in shea butter, contain fat and aliphatic acid etc., there is potent moisten Water supplement function, it can effectively strengthen skin elasticity, therefore the women in Africa and children can utilize shea butter to smear whole body skin, To prevent the powerful dust storm in Sahara Desert from becoming arid coarse by skin.In addition, it also contains substantial amounts of unsaponifiable lipid (unsaponifiable fats), it is possible to provide abundant Alphalin, D, E, F etc., for nutrient needed for skin supplement after, more have Synergidae is more raw and promotes microcirculation, therefore for preventing aging, dry skin explosion, the healing of even tiny wound from having Certain help.
Gadol extract:Gadol extract is the extract of rhodiola root root, and gas is fragrant and sweet, bitter and puckery flavor.Main Ingredients and Appearance For rhodioside and rhodiola root aglycon, there is effective oxidation resistance, the detrimental effect injured by restraint of liberty base, it can Effectively resist and cause disease because of aging.
Preferably, the Cordyceps extract, the wooden berry extract of breast, the weight ratio of gadol extract are:The worm summer in winter Careless extract:The wooden berry extract of breast:Gadol extract=(2~6):12:14.Above-mentioned weight than Cordyceps extract, The wooden berry extract of breast, gadol extract, performance synergistic function that can be best play more preferable anti-aging effect.
It is highly preferred that the Cordyceps extract, the wooden berry extract of breast, the weight ratio of gadol extract are:Winter worm Summer grass extract:The wooden berry extract of breast:Gadol extract=3:12:14.Above-mentioned weight than Cordyceps extract, breast wood Berry extract, gadol extract, performance synergistic function that can be best, play more preferable anti-aging effect.
Preferably, the Cordyceps extract includes Cordyceps sporophore extract and cordyceps sinensis polypide is extracted Thing, the weight ratio of the Cordyceps sporophore extract and Cordyceps sporophore extract are:Cordyceps sporophore extracts Thing:Cordyceps sporophore extract=2:(10~15).
Cordyceps sinensis is precious from head to foot, is referred to as soft gold, seven major class activity of fighting against senium recognized by current medical field into In point, cordyceps sinensis just covers five major classes, is polysaccharide, amino acid, polypeptide (protein), nucleic acid and vitamin respectively, so using worm Careless skin care can meet a variety of demands of skin, the aging speed of delaying skin.Wherein, polypide mainly contains Cordycepin, worm The multiple efficacies composition such as oxalic acid, adenosine and polysaccharide, the antioxidant activity tests of Cordyceps sporophore extract show:To hydroxyl certainly By base has stronger Scavenging activity, the peroxidating to lipid is inhibited, has to liver cancer cells 7402 and HELA cells Inhibitory action, and lengthen the life effect with antifatigue and drosophila., can not only by fruiting body extract and polypide extract in the application The effect of making full use of in cordyceps sinensis composition, moreover it is possible to cost-effective.
It is highly preferred that the weight of the Cordyceps sporophore extract and Cordyceps sporophore extract ratio is:Winter worm Summer grass fruiting body extract:Cordyceps sporophore extract=2:14.
Preferably, the composition also includes the composition of following parts by weight:5~10 parts of wolfberry fruit extract, cactus extraction 10~15 parts of thing.
Wolfberry fruit extract:Modern aging theory thinks, the main reason for causing body's immunity to be degenerated in aging course It is thymus gland atrophy with advancing age, thymus gland is the key link of aging.LBP-X in the fruit of Chinese wolfberry, it is main in human body Selection index system and thymus T cells are wanted, LBP-X, which can be caught into mature cell number, to be increased, and strengthens air emptying function, makes chest Gland cell moves to outer planet to be increased, and can reverse the thymus gland retrogression of aging.LBP-X can also strengthen marrow hemopoiesis work( Can, so the fruit of Chinese wolfberry has anti-aging effects.
Radix et Caulis Opuntiae Dillenii extract:Containing a variety of Flavonoid substances, there is extraordinary beauty and skin care effect, can not only strengthen flesh The fine and smooth sense of skin and elasticity, while moist, anti-anaphylaxis, anti-inflammatory and other effects can also be played.
It is highly preferred that the Cordyceps extract, wolfberry fruit extract, the weight ratio of Radix et Caulis Opuntiae Dillenii extract are:The worm summer in winter Careless extract:Wolfberry fruit extract:Radix et Caulis Opuntiae Dillenii extract=(2~6):7:13.Above-mentioned weight than Cordyceps extract, matrimony vine Extract, Radix et Caulis Opuntiae Dillenii extract's thing Synergistic, can preferably promote the absorption of Cordyceps extract active ingredient, reach more Good anti-aging moist effect.
It is highly preferred that the Cordyceps extract, wolfberry fruit extract, the weight ratio of Radix et Caulis Opuntiae Dillenii extract are:The worm summer in winter Careless extract:Wolfberry fruit extract:Radix et Caulis Opuntiae Dillenii extract=3:7:13.Above-mentioned weight than Cordyceps extract, matrimony vine extraction Thing, Radix et Caulis Opuntiae Dillenii extract's thing Synergistic, can preferably promote the absorption of Cordyceps extract active ingredient, reach more preferable Anti-aging moist effect.
Meanwhile the present invention also provides a kind of skin care item of the anti-aging composition.
In addition, it is noted that skin care item of the present invention can also include auxiliary material, the selection of auxiliary material has no tool herein Body limits, and those skilled in the art can carry out conventional selection such as water, alcohols, finish, surfactant, pH according to being actually needed The auxiliary materials such as conditioning agent, antioxidant or preservative.In addition, skin care item of the present invention can be made creme, emulsion, essence lotion, The diversified forms such as gel or facial mask, the present invention have no specific restriction to this, and those skilled in the art can also be according to actual need Carry out conventional selection.
Relative to prior art, beneficial effects of the present invention are:
In anti-aging composition of the present invention, Cordyceps extract, the wooden berry extract of breast, gadol extract are mixed Close and use, one side three can play synergistic function jointly, reach more preferable anti-aging moist effect, on the other hand, breast Wooden berry extract, gadol extract can further promote skin to fully absorb functional component in Cordyceps extract, Its nursing role to skin is more fully more preferably played, further reaches more preferable anti-aging effect;By of the present invention group Compound is applied in skin care item, can be long-term use of, and anti-aging effect is preferably nourished in substantially playing for being grown from skin.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.Skin care item described in the embodiment of the present invention can also include auxiliary material, and auxiliary material selection has no specific restriction herein, this Art personnel can carry out conventional selection such as water, alcohols, finish, surfactant, pH adjusting agent, anti-according to being actually needed The auxiliary material such as oxidant or preservative, in addition, the skin care item in embodiment are analyzed its performance only by taking essence lotion as an example, but not Limitation and this, the compliance test result of other such as skin care item of creme, emulsion, gel or facial mask diversified forms is similarly.
5 kinds of embodiments of anti-aging composition of the present invention, with weight ratio meter, anti-aging group described in embodiment 1~5 The composition and content of compound are as shown in table 1:
Composition and content in the embodiment 1~5 of table 1 in anti-aging skin care product
Skin care item are made in composition in above-described embodiment 1~5, the skin care item are Essence, and the Essence also wraps Composition containing following weight/mass percentage composition:Propane diols 2%, butanediol 3%, hydrolysis Jojoba esters 0.4%, Sodium Hyaluronate 0.03%th, essence and preservative, appropriate amount of water.
Embodiment 6
Strengthen skin elasticity compliance test result
Subject Population is divided into 5 groups, every group of 20 people, the tested objective packet of crowd, and it is ignorant to product composition, exclude Influence of the psychological factor to the product overall evaluation.Each group of people uses the skin-protection product of embodiment 1~5 respectively.Before sample is smeared, by Examination person is using the gentle cleaning agent cleaning face of identical, and symmetric position selectes about 5 × 5cm at left and right sides of subject face2Greatly The skin-protection product that about 0.5g each groups accordingly use is smeared, frequency of use is once in the morning and once at night, even as Experimental Area in small region It is continuous to use daily.
Before the skin-protection product of embodiment 1~5, in every subject's test zone Callegari soft plus The each experiment position initial elasticity m of spring probe detection of skinanalysis apparatus0Value, is repeated 5 times, draws average value respectively.Make With being detected respectively again at these positions after 2,4,6 weeks, each test zone respectively 5 hypoelasticity m values of detection, and obtain the period 5 Secondary m average value.
In order to preferably evaluate the data obtained, the m detected every time respectively divided by is not used the m of sample0Averagely it is worth to The elasticity grading at the position, when elastic grading value is bigger, illustrate that sample increase skin elasticity is more obvious.Use embodiment 1~5 The elasticity grading of product is as shown in table 2.
The elasticity grading of the product of 2 embodiment of table 1~5
From table 2 it can be seen that using after 6 weeks, using the skin care item in the embodiment of the present invention 1~5, higher bullet is respectively provided with Property grading, this explanation embodiment 1~5 in skin care item anti-aging effect it is fine, wherein using the skin care item in embodiment 1 Elasticity grading highest, this explanation embodiment 1 in skin care item anti-aging effect it is best;Meanwhile using after 6 weeks, embodiment 1 The elasticity grading of middle skin care item is graded higher than the elasticity of the skin care item of embodiment 2 and 3, and the elasticity grading of skin care item is high in embodiment 1 In the elasticity grading of the skin care item of embodiment 4 and 5, this is also why the application selects Cordyceps extract:The wooden fruit extraction of breast Thing:Gadol extract=3:12:14, Cordyceps extract:Wolfberry fruit extract:Radix et Caulis Opuntiae Dillenii extract=3:7:13, winter worm Summer grass fruiting body extract:Cordyceps sporophore extract=2:14 the reason for.
Embodiment 7
Experiment is divided into control group and experimental group, and experimental group 1~5 is respectively prepared skin care item in embodiment 1~5, is compareed Component is 6 groups, and contained component is except Cordyceps extract, the wooden berry extract of breast, rhodiola root in the skin care item of control group 1~6 The weight of three kinds of compositions of extract is outer than different, and Cordyceps extract, the wooden berry extract of breast, three kinds of gadol extract into Total amount point in skin care item is identical, and other compositions are same as Example 1, and cordyceps sinensis extracts in specific control group 1~6 Thing, the wooden berry extract of breast, the ratio of three kinds of compositions of gadol extract are as shown in table 3:
Cordyceps extract, the wooden berry extract of breast, the ratio of three kinds of compositions of gadol extract in the control group skin care item of table 3 Example content
Group 1 2 3 4 5 6
Cordyceps extract 3 0 0 0 3 3
The wooden berry extract of breast 0 12 0 12 12 0
Gadol extract 0 0 14 14 0 14
In control group and experimental group, choose 100 ages for every group and carry out research on probation in the volunteer of 20~50 years old, it is real Test the skin care item that the subjects of group 1~5 are prepared using embodiment 1~5 respectively, the subjects difference of control group 1~6 The skin care item being prepared using control group 1~6, skin care item application method as in embodiment 6, if after 6 weeks, measure bullet Property grading be higher than 1.60, be considered as effectively, statistics is efficient, as a result as shown in table 4.
The effective situation statistical result of elasticity grading in the experimental group of table 4 and control group
As seen from Table 4, Cordyceps extract, the wooden berry extract of breast, red is comprised only in the skin care item of control group 1~6 One kind in three kinds of compositions of red-spotted stonecrop extract, two kinds, without good anti-aging effect.And in the skin care item of experimental group 1~5 Containing three kinds of compositions, there is good anti-aging effect.Thus it is provable, in skin care item of the invention, Cordyceps extract, Three kinds of wooden berry extract of breast, gadol extract compositions have the function that to mutually promote, mutually cooperateed with, and can play significant anti- Aging effects.
Embodiment 8
Experiment is divided into control group and experimental group, and experimental group 1~5 is respectively prepared skin care item in embodiment 1~5, is compareed Component is 6 groups, and contained component is removed Cordyceps extract, wolfberry fruit extract, cactus and carried in the skin care item of control group 1~6 Take the weight of three kinds of compositions of thing outer than different, and three kinds of Cordyceps extract, wolfberry fruit extract, Radix et Caulis Opuntiae Dillenii extract compositions exist Total amount in skin care item is identical, and other compositions are same as Example 1, Cordyceps extract, Chinese holly in specific control group 1~6 Qi extract, the ratio of three kinds of compositions of Radix et Caulis Opuntiae Dillenii extract are as shown in table 5:
Cordyceps extract, wolfberry fruit extract, the ratio of three kinds of compositions of Radix et Caulis Opuntiae Dillenii extract in the control group skin care item of table 5 Content
Group 1 2 3 4 5 6
Cordyceps extract 3 0 0 0 3 3
Wolfberry fruit extract 0 7 0 7 7 0
Radix et Caulis Opuntiae Dillenii extract 0 0 13 13 0 13
In control group and experimental group, choose 100 ages for every group and carry out research on probation in the volunteer of 20~50 years old, it is real Test the skin care item that the subjects of group 1~5 are prepared using embodiment 1~5 respectively, the subjects difference of control group 1~6 The skin care item being prepared using control group 1~6, skin care item application method as in embodiment 6, if after 6 weeks, measure bullet Property grading be higher than 1.60, be considered as effectively, statistics is efficient, as a result as shown in table 6.
The effective situation statistical result of elasticity grading in the experimental group of table 6 and control group
Group Efficiently individual quantity It is efficient
Control group 1 7 7%
Control group 2 5 5%
Control group 3 6 6%
Control group 4 13 13%
Control group 5 15 15%
Control group 6 19 19%
Experimental group 1 69 69%
Experimental group 2 52 52%
Experimental group 3 50 50%
Experimental group 4 58 58%
Experimental group 5 59 59%
As seen from Table 6, Cordyceps extract, wolfberry fruit extract, celestial being are comprised only in the skin care item of control group 1~6 One kind for slapping in three kinds of compositions of extract, two kinds, without good anti-aging effect.And contain in the skin care item of experimental group 1~5 There are three kinds of compositions, there is good anti-aging effect.Thus it is provable, in skin care item of the invention, Cordyceps extract, Chinese holly Three kinds of Qi extract, Radix et Caulis Opuntiae Dillenii extract compositions have the function that to mutually promote, mutually cooperateed with, and can play significant anti-aging Effect.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention And scope.

Claims (9)

1. a kind of anti-aging composition, it is characterised in that include the composition of following parts by weight:2~6 parts of Cordyceps extract, Wooden 10~15 parts of the berry extract of breast, 8~17 parts of gadol extract.
2. anti-aging composition as claimed in claim 1, it is characterised in that the wooden fruit extraction of the Cordyceps extract, breast Thing, the weight ratio of gadol extract are:Cordyceps extract:The wooden berry extract of breast:Gadol extract=(2~6): 12:14。
3. anti-aging composition as claimed in claim 2, it is characterised in that the wooden fruit extraction of the Cordyceps extract, breast Thing, the weight ratio of gadol extract are:Cordyceps extract:The wooden berry extract of breast:Gadol extract=3:12:14.
4. the anti-aging composition as described in any one of claims 1 to 3, it is characterised in that the Cordyceps extract bag Include Cordyceps sporophore extract and Cordyceps sporophore extract, the Cordyceps sporophore extract and cordyceps sinensis The weight ratio of polypide extract is:Cordyceps sporophore extract:Cordyceps sporophore extract=2:(10~15).
5. anti-aging composition as claimed in claim 4, it is characterised in that the Cordyceps sporophore extract and winter worm The weight ratio of summer grass-and-insect painting body extract is:Cordyceps sporophore extract:Cordyceps sporophore extract=2:14.
6. the anti-aging composition as described in any one of claims 1 to 3, it is characterised in that the composition is also comprising following The composition of parts by weight:5~10 parts of wolfberry fruit extract, 10~15 parts of Radix et Caulis Opuntiae Dillenii extract.
7. anti-aging composition as claimed in claim 6, it is characterised in that the Cordyceps extract, wolfberry fruit extract, The weight ratio of Radix et Caulis Opuntiae Dillenii extract is:Cordyceps extract:Wolfberry fruit extract:Radix et Caulis Opuntiae Dillenii extract=(2~6):7:13.
8. anti-aging composition as claimed in claim 7, it is characterised in that the Cordyceps extract, wolfberry fruit extract, The weight ratio of Radix et Caulis Opuntiae Dillenii extract is:Cordyceps extract:Wolfberry fruit extract:Radix et Caulis Opuntiae Dillenii extract=3:7:13.
A kind of 9. skin care item for including any one of the claim 1~8 anti-aging composition.
CN201711055450.0A 2017-10-31 2017-10-31 A kind of anti-aging composition and the skin care item containing said composition Withdrawn CN107811909A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431888A (en) * 2018-10-17 2019-03-08 芜湖市传世信息技术有限公司 A kind of anti-aging composition and contain this group of materialization cosmetic
CN110420138A (en) * 2019-08-28 2019-11-08 宇妥藏药股份有限公司 A kind of root of kirilow rhodiola anti-oxidant face mask liquid and preparation method thereof, application
CN110934787A (en) * 2019-11-27 2020-03-31 陈少威 Anti-aging composition and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1310021A (en) * 2001-01-11 2001-08-29 王东桥 Health giving and face nursing composition of natural material
CN101125119A (en) * 2007-07-18 2008-02-20 西藏宇妥藏药研究有限公司 Tibetan materia medica with whitening anti-senility function and application thereof
CN106074319A (en) * 2016-05-31 2016-11-09 安徽皖斛堂生物科技有限公司 A kind of Herba Dendrobii facial film and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1310021A (en) * 2001-01-11 2001-08-29 王东桥 Health giving and face nursing composition of natural material
CN101125119A (en) * 2007-07-18 2008-02-20 西藏宇妥藏药研究有限公司 Tibetan materia medica with whitening anti-senility function and application thereof
CN106074319A (en) * 2016-05-31 2016-11-09 安徽皖斛堂生物科技有限公司 A kind of Herba Dendrobii facial film and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431888A (en) * 2018-10-17 2019-03-08 芜湖市传世信息技术有限公司 A kind of anti-aging composition and contain this group of materialization cosmetic
CN110420138A (en) * 2019-08-28 2019-11-08 宇妥藏药股份有限公司 A kind of root of kirilow rhodiola anti-oxidant face mask liquid and preparation method thereof, application
CN110934787A (en) * 2019-11-27 2020-03-31 陈少威 Anti-aging composition and preparation method thereof
CN110934787B (en) * 2019-11-27 2022-04-19 陈少威 Anti-aging composition and preparation method thereof

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Application publication date: 20180320