CN111094991A

CN111094991A - Blood analyzer and control method thereof

Info

Publication number: CN111094991A
Application number: CN201780093861.0A
Authority: CN
Inventors: 张明伟; 许海清
Original assignee: Beijing Precil Instrument Co Ltd
Current assignee: Beijing Precil Instrument Co Ltd
Priority date: 2017-08-16
Filing date: 2017-08-16
Publication date: 2020-05-01
Also published as: EP3671218A1; WO2019033312A1; EP3671218A4

Abstract

A blood analyzer (1) and a control method of the blood analyzer (1), the blood analyzer (1) comprises a sample conveying module (11) for conveying a sample to be detected, a dispensing module (13) for sucking and discharging the sample or reagent, a sample incubation module (14) for incubating the sample, a reagent storage module (15) for storing the reagent, a transfer module (16) for transferring a reaction cup and a sample detection module (17) for detecting the sample; the dispensing module (13) can transfer the sample from the sample conveying module (11) to a reaction cup of the sample incubation module (14), and the dispensing module (13) can also transfer the reagent from the first reagent storage mechanism (151) to the reaction cup of the sample incubation module (14) or the reaction cup of the sample detection module (17); the transfer module (16) is capable of transferring the reaction cups in the sample incubation module (14) to the sample detection module (17). The blood analyzer (1) is easy to realize modular operation, convenient to add modules to realize corresponding functions and easy to expand.

Description

Blood analyzer and control method thereof

Technical Field

The present invention relates to the technical field of medical equipment, and in particular, to a blood analyzer for analyzing samples such as blood and a control method thereof.

Background

The full-automatic coagulation analyzer is used for analyzing coagulation and anticoagulation, fibrinolysis and anti-fibrinolysis functions of blood. Currently, fully automatic coagulation analyzers generally include: sample storage device, reagent cold storage plant, testing arrangement, application of sample device, grab a cup device and advance a cup device automatically. The work flow is basically as follows: the automatic cup feeding device conveys the test cup to a cup grabbing position, a cup grabbing hand in the cup grabbing device conveys the blood coagulation test cup to the test position of the test device from the cup grabbing position, a sample adding needle in the sample adding device conveys a blood sample in the sample storage device and a reaction reagent in the reagent refrigerating device to the test cup in the test position, the sample and the reagent react in the test cup, and the test device measures a reaction result.

At present, when an X/Y/Z motion mechanism is adopted by a full-automatic coagulation analyzer to realize the automatic operation of coagulation detection, the problems of difficult modularization realization and difficult expansion exist; and when the sample adding device and the reagent refrigerating device of the full-automatic blood coagulation analysis independently move to realize the automatic operation of blood coagulation detection, the full-automatic blood coagulation analyzer cannot realize better functions due to the limitation of the layout of all components. From this, the whole device of full-automatic blood coagulation analysis appearance is difficult to realize the modularization, is difficult for expanding, can not make full-automatic blood coagulation analysis appearance realize better function, influences the use.

Disclosure of Invention

In view of the above, it is necessary to provide a blood analyzer that can be easily modularized and easily expanded, and a control method applied to the blood analyzer, in order to solve the problem that the current fully automatic coagulation analyzer is not easily modularized and not easily expanded.

The above purpose is realized by the following technical scheme:

a blood analyzer comprises a sample conveying module for conveying a sample to be detected, a separate injection module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a reagent storage module for storing the reagent, a transfer module for transferring a reaction cup and a sample detection module for detecting the sample;

the sample incubation module is arranged in a disc-shaped structure, a plurality of placing positions for placing reaction cups are arranged on the sample incubation module, and the sample incubation module can rotate and drive the reaction cups in the placing positions to rotate;

the reagent storage module comprises a rotatable first reagent storage mechanism which is arranged in a disc-shaped structure, and the first reagent storage mechanism can store a plurality of reagents; the first reagent storage mechanism is arranged separately from the sample incubation module;

the transfer module is capable of transferring the reaction cup into the placement position of the sample incubation module;

the dispensing module is capable of transferring a sample from the sample transport module into the reaction cup of the sample incubation module, the dispensing module is further capable of transferring a reagent from the first reagent storage mechanism into the reaction cup of the sample incubation module or the reaction cup of the sample detection module;

the transfer module is capable of transferring the reaction cups in the sample incubation module to the sample detection module.

the reagent storage module comprises a rotatable first reagent storage mechanism capable of storing a plurality of reagents;

the sample detection module comprises a magnetic bead method detection mechanism and an optical method detection mechanism, the magnetic bead method detection mechanism carries out magnetic bead method detection on the sample, and the optical method detection mechanism carries out optical method detection on the sample;

the transfer module can transfer the reaction cup in the sample incubation module to the magnetic bead method detection mechanism or the optical method detection mechanism.

A blood analyzer comprises a cup inlet module for conveying a reaction cup, a sample conveying module for conveying a sample to be detected, a separate injection module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a transfer module for transferring the reaction cup, a reagent storage module for storing the reagent, a sample detection module for detecting the sample and a recovery module;

the transfer module is capable of transferring the reaction cup into the placement position of the sample incubation module, the dispensing module is capable of transferring a sample from the sample transport module into the reaction cup of the sample incubation module, the dispensing module is further capable of transferring a reagent from the first reagent storage mechanism into the reaction cup of the sample incubation module or the reaction cup of the sample detection module;

the transfer module is capable of transferring the reaction cups in the sample incubation module to the sample detection module; the transfer module can also transfer the reaction cup which is detected by the sample detection module to the recovery module;

the recovery module is provided with a cup losing opening, the cup feeding module is provided with an empty cup taking station, the blood analyzer is provided with a cup taking and placing station corresponding to the sample incubation module, the sample detection module is provided with a detection station, and the cup losing opening, the cup taking and placing station and at least three collinear settings in the detection station correspond to the movement track of the transfer module.

A control method of a blood analyzer comprises a sample conveying module for conveying a sample to be detected, a dispensing module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a transfer module for transferring a reaction cup and a sample detection module for detecting the sample;

the control method of the blood analyzer comprises the following steps:

acquiring detection information of a sample test item;

the transfer module is capable of placing the empty reaction cup into the placement position of the sample incubation module;

the dispensing module sucks a sample at the sample conveying module or a reagent at the reagent storage module and adds the sample or the reagent to the reaction cup of the sample incubation module;

the transfer module can transfer the reaction cup added with the sample and the reagent to the magnetic bead method detection mechanism or the optical method detection mechanism.

After the technical scheme is adopted, the invention has the beneficial effects that:

when the blood analyzer detects a sample, the transfer module transfers the reaction cup to the sample incubation module, and the sample conveying module conveys the sample to be detected; the dispensing module can absorb the sample conveyed by the sample conveying module and transfer the sample into a reaction cup of the sample incubation module, and the dispensing module can also absorb the reagent in the reagent storage module and transfer the reagent into the reaction cup of the sample incubation module; the transfer module conveys the reaction cups in the sample incubation module to the sample detection module for detection; the blood analyzer comprises a blood analyzer body, a blood coagulation analyzer body, a control module and a module, wherein the blood analyzer body is provided with a plurality of parts, the parts are arranged in the blood analyzer body, and the control module is used for controlling the blood coagulation analyzer body to perform modular operation.

Drawings

FIG. 1 is a perspective view of a blood analyzer according to an embodiment of the present invention, viewed from one direction;

FIG. 2 is a perspective view of the blood analyzer shown in FIG. 1, viewed from another direction;

FIG. 3 is a top view of the blood analyzer shown in FIG. 1;

FIG. 4 is a perspective view of a first reagent storage mechanism in the blood analyzer shown in FIG. 1;

FIG. 5 is a perspective view of the reagent disk of the first reagent storage mechanism of FIG. 4 with one of the reagent racks removed from the bottom disk;

FIG. 6 is a perspective view of a sample transport module in the hematology analyzer shown in FIG. 1;

FIG. 7 is a perspective view of the sample delivery module shown in FIG. 6 with the sample delivery cap removed;

FIG. 8 is a perspective view of a portion of a cup access module of the blood analyzer shown in FIG. 2;

FIG. 9 is a perspective view of a magnetic bead method detection mechanism in the blood analyzer shown in FIG. 1;

FIG. 10 is a perspective view of a first optical detection mechanism in the blood analyzer shown in FIG. 1;

FIG. 11 is a perspective view of a first transfer mechanism in the blood analyzer shown in FIG. 1;

fig. 12 is a perspective view of a second transfer mechanism in the blood analyzer shown in fig. 1;

FIG. 13 is a perspective view of a sample incubation module of the hematology analyzer of FIG. 1;

FIG. 14 is a top view of the hematology analyzer shown in FIG. 1 showing a recovery module;

FIG. 15 is a perspective view of a stirring module in the blood analyzer shown in FIG. 1;

FIG. 16 is a perspective view of a puncture needle mechanism in the blood analyzer shown in FIG. 1;

FIG. 17 is a perspective view of the integrated needle mechanism in the blood analyzer shown in FIG. 1;

FIG. 18 is a perspective view of a reagent needle mechanism in the blood analyzer shown in FIG. 1;

FIG. 19 is a top view of the blood analyzer shown in FIG. 1 showing a reagent needle clearance space;

FIG. 20 is a schematic view of the motion trajectory of the stirring rod of the stirring module shown in FIG. 15;

FIG. 21 is a perspective view of a blood analyzer according to another embodiment of the present invention, viewed from one direction;

FIG. 22 is a perspective view of the blood analyzer of FIG. 21 viewed from another direction;

FIG. 23 is a top view of the blood analyzer shown in FIG. 21;

FIG. 24 is a top view of a blood analyzer according to still another embodiment of the present invention;

wherein:

1-a blood analyzer;

10-testing the box body;

101-a test platform; 102-a mounting frame; 103-a cover plate; 104-a placement cavity;

11-a sample transport module;

111-a detection component; 112-a rotating assembly; 113-a scanning mechanism; 114-a sampling assembly; 115-a loading assembly; 116-an unloading assembly; 117-a swivel assembly; 118-a sample transport floor; 119-a sample transport ceiling; 1191-a swipe card component;

12-a cup feeding module;

121-cup entering support;

122-reaction cup storage mechanism; 1221-reaction cup storage tray; 1222-a stripping member;

123-a reaction cup conveying mechanism;

124-reaction cup transfer mechanism; 1241-cuvette carrier; 1242-a barrier member;

13-a dispensing module;

131-a puncture needle mechanism;

1311-puncture needle support;

1312-a puncture needle lifting driving assembly; 13121-puncture needle lifting drive motor; 13122-puncture needle elevation transmission member;

1313-a needle rotation drive assembly; 13131-puncture needle rotation driving motor; 13132-a puncture needle rotation transmission member;

1314-puncture needle mounting assembly; 13141-puncture needle rotating shaft; 13142-a puncture needle rotating arm;

1315-puncture needle;

132-a synthetic needle mechanism;

1321-synthetic needle support;

1322-a synthetic needle lifting drive assembly; 13221-integrated needle lifting drive motor; 13222-integrated needle lifting transmission means;

1323-integrated needle rotary drive assembly; 13231-synthetic needle rotation driving motor; 13232-integrated needle rotation transmission means;

1324-synthetic needle mounting assembly; 13241-synthetic needle spindle; 13242-integrated needle rotation arm;

1325-general needle;

1326-comprehensive needle liquid level detection plate;

133-a reagent needle mechanism;

1331-reagent needle support;

1332-a reagent needle elevation drive assembly; 13321-a reagent needle lifting drive motor; 13322-reagent needle elevation drive means;

1333-a reagent needle rotation drive assembly; 13331-reagent needle rotation drive motor; 13332-reagent needle rotation transmission means;

1334-a reagent needle mounting assembly; 13341-reagent needle spindle; 13342-reagent needle rotation arm;

1335-reagent needle; 13351-first reagent needle; 13352-a second reagent needle;

1336-reagent needle heating control board;

1337-detecting the liquid level of the reagent needle;

134-a dispensing needle mechanism;

14-a sample incubation module;

141-incubation support;

142-an incubation drive mechanism; 1421-incubation drive motor; 1422-incubation transmission;

143-a sample incubation mechanism; 1431-incubation tray; 14311-place bit; 1432-insulating pot;

15-a reagent storage module;

151-a first reagent storage mechanism;

1511-reagent mounting bracket;

1512-reagent pot;

1513-reagent disk; 15131-tray; 15132-reagent rack; 151321-storage location;

1514-a first reagent drive assembly; 15141-a first reagent drive motor; 15142-a first reagent drive component;

152-a second reagent storage mechanism;

16-a transfer module;

161-a first transfer mechanism; 1611-a first transfer mounting plate; 1612-first grasping drive assembly; 1613-a first cup portion; 1614-a first resilient member; 1615-a first transfer drive assembly; 1616-a first sliding track;

162-a second transfer mechanism; 1621-a second transfer mounting plate; 1622-a second grasping drive assembly; 1623-a second cup portion; 1624-a second transfer drive assembly; 1625-a second sliding track; 1626-a third transfer drive assembly; 1627-a third sliding track;

17-a sample detection module;

171-a magnetic bead method detection mechanism; 1711-magnetic bead support frame; 1712-magnetic bead detection seat; 17121-magnetic bead detection site; 1713-magnetic bead control board;

172-a first optical detection mechanism; 1721-a first optical support; 1722-a first optical detection mount; 17221-first optical detection bit; 1723-a first optical receiver plate;

173-a second optical detection mechanism;

18-a recovery module;

181-first cup losing mouth; 182-a second cup losing mouth;

19-a stirring module;

191-a first stirring support plate;

192-a second stir support plate;

193-a first agitation drive mechanism;

194 — a second stirring drive mechanism; 1941-a second stirring driving motor; 1942-a second agitation drive member;

195-a stirring mounting mechanism; 1951-stirring shaft; 1952-stirring cantilever;

196-a stirring rod;

20-a cleaning module;

201-puncture needle cleaning mechanism; 2011-puncture needle cleaning pool; 2012-a sump;

202-integrated needle cleaning mechanism;

203-reagent needle cleaning mechanism;

204-a stir bar cleaning mechanism;

21-a liquid path module;

22-main control module.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the blood analyzer of the present invention is further described in detail by the following embodiments with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings). In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.

In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

Referring to fig. 1 to 3 and fig. 21 to 24, the present invention provides a blood analyzer 1, wherein the blood analyzer 1 is used for analyzing and detecting a sample to be detected to obtain a corresponding detection result, so as to meet a use requirement. It should be noted that the specific type of sample to be tested is not limited, and in some embodiments, the sample to be tested includes a solid sample or a liquid sample. It can be understood that the liquid sample needs to be placed on the sample holder for detection. Further liquid samples include, but are not limited to, blood samples. When a blood sample is tested using the blood analyzer 1 of the present invention, the blood sample is stored in a test tube and sequentially placed on a test tube rack. The blood analyzer 1 of the present invention is easy to implement modular operation, effectively solves the problem that the prior fully automatic coagulation analyzer is not easy to implement modularization and expand, is convenient to add modules on the blood analyzer 1 to implement corresponding functions, is easy to expand, and simultaneously, can also enable the blood analyzer 1 of the present invention to implement better functions, improve operation efficiency, and is convenient to use.

In one embodiment of the present invention, the blood analyzer 1 includes a sample transfer module 11, a cup entering module 12, a dispensing module 13, a sample incubation module 14, a reagent storage module 15, a transfer module 16, and a sample detection module 17. The sample conveying module 11 is used for conveying samples to be detected so as to realize automatic conveying of the samples to be detected, improve the sample introduction efficiency and further improve the working efficiency of the blood analyzer 1. The cup feeding module 12 is used for conveying reaction cups so as to realize automatic conveying of empty reaction cups and improve conveying efficiency. The dispensing module 13 is used for sucking and discharging samples or reagents to realize the addition of the samples or reagents into corresponding reaction cups. The sample incubation module 14 is used for incubating the sample to achieve optimal reaction conditions for the sample, thereby facilitating the detection of sample parameters. The reagent storage module 15 is used for storing reagents, can store various reagents required in sample detection, is convenient for selecting the required reagents, and improves the efficiency of reagent absorption. The transfer module 16 is used for transferring the reaction cups, so that the reaction cups can move to various positions of the blood analyzer 1, automatic analysis and detection of samples are realized, and the operation efficiency is improved. The sample detection module 17 is used for detecting the sample to obtain the corresponding parameter of the sample. Of course, in other embodiments of the present invention, the cup entering module 12 may be replaced, that is, the reaction cup may be directly placed in the sample incubation module 14 without using the cup entering module 12 to transport the reaction cup. Alternatively, the cuvettes delivered by the cuvette inlet module 12 are usually disposable consumables, but of course, the cuvettes may be recycled. Alternatively, when the reaction cup is recycled, the cup feeding module 12 may not be used to transport the reaction cup.

The sample incubation module 14 is arranged in a disc-shaped structure, a plurality of placing positions 14311 for placing reaction cups are arranged on the sample incubation module 14, and the sample incubation module 14 can rotate and drive the reaction cups in the placing positions 14311 to rotate. The sample incubation mechanism 143 has a heating function, and is configured to heat the sample and the reagent in the reaction cup, so as to achieve an incubation function. The sample incubation module 14 is capable of heating the sample and reagents to about 34 ℃ prior to the actual measurement to ensure that the reaction is proceeding properly.

Reagent storage module 15 sets up and rotatable first reagent storage mechanism 151 including being discoid structure, and first reagent storage mechanism 151 can deposit multiple reagent, can also realize the refrigeration and the bar code automatic identification of multiple reagent. The first reagent storage mechanism 151 has a refrigeration function for storing a low-temperature reagent and storing the reagent.

Furthermore, the first reagent storage mechanism 151 is provided separately from the sample incubation module 14. That is, the first reagent storage mechanism 151 and the sample incubation module 14 are separately provided with a certain distance therebetween. Preferably, in an embodiment of the present invention, the sample incubation module 14 is disposed side by side with the first reagent storage mechanism 151. Of course, in other embodiments of the present invention, the sample incubation module 14 and the first reagent storage mechanism 151 may be arranged in a staggered manner. Moreover, the sample conveying module 11 is located at one side of the sample incubation module 14 and the first reagent storage mechanism 151, and the cup entering module 12, the transfer module 16 and the sample detection module 17 are located at the other side of the sample incubation module 14 and the first reagent storage mechanism 151; the cup feeding module 12 is disposed at the outer side of the sample detecting module 17 and the sample incubating module 14, the transferring module 16 is located above the sample detecting module 17, and the transferring module 16 can move among the cup feeding module 12, the sample incubating module 14 and the sample detecting module 17. The transfer module 16 can transfer the reaction cups delivered by the cup entering module 12 to the placing position 14311 of the sample incubation module 14, and the transfer module 16 can transfer the reaction cups in the sample incubation module 14 to the sample detection module 17.

The dispensing module 13 can transfer the sample from the sample transport module 11 to the reaction cup of the sample incubation module 14, and the dispensing module 13 can also transfer the reagent from the first reagent storage mechanism 151 to the reaction cup of the sample incubation module 14 or the reaction cup of the sample detection module 17. The dispensing module 13 sucks a sample in the sample conveying module 11, and then adds the sample into a reaction cup of the sample incubation module 14; subsequently, the dispensing module 13 sucks the reagent again in the first reagent storage mechanism 151, and transfers the reagent into the reaction cup of the sample incubation module 14.

The transfer module 16 is capable of transferring empty reaction cups delivered into the cup module 12 into the placement location 14311 of the sample incubation module 14. The transfer module 16 is capable of transferring the cuvettes in the sample incubation module 14 to the sample detection module 17. The blood analyzer 1 is provided with a pick-and-place cup station, a dispensing station and a cup-taking station surrounding the sample incubation module 14. The sample incubation module 14 moves to a cup taking and placing station, and the transfer module 16 places the reaction cup which is emptied at the cup feeding module 12 in a cup taking and placing station into a placing position 14311 of the sample incubation module 14 corresponding to the cup taking and placing station; subsequently, the sample incubation module 14 drives the reaction cup to move to a dispensing station, and the dispensing module 13 transfers the sample from the sample conveying module 11 to the reaction cup of the sample incubation module 14 or transfers the reagent from the first reagent storage mechanism 151 to the reaction cup of the sample incubation module 14 at the dispensing station; after the sample and the reagent are added into the reaction cup, the sample incubation module 14 drives the reaction cup to move to a cup taking and placing station or a cup taking station, the transfer module 16 grabs the reaction cup added with the sample and the reagent at the cup taking and placing station or the cup taking station, and transfers the reaction cup to the sample detection module 17 for detection. It is understood that the cup taking and placing station and the cup taking station can be the same position, and the transfer module 16 places or grasps the reaction cup at the same position; of course, in order to improve efficiency, the cup taking and placing station and the cup taking station are two different positions, and the transfer module 16 can grasp the reaction cups at different positions. It should be noted that, the order of adding the sample and the reagent is not limited, and the sample may be added in the reaction cup first, and then the reagent may be added; of course, the reagent may be added first in the cuvette and then the sample may be added.

The blood analyzer 1 has a reagent aspirating station corresponding to the first reagent storage mechanism 151, and the dispensing module 13 aspirates a reagent at the reagent aspirating station. A plurality of reagents are stored in the first reagent storage mechanism 151, when a certain reagent needs to be added to a sample, the first reagent storage mechanism 151 rotates to enable the corresponding reagent to rotate to the reagent sucking station, and meanwhile, the dispensing module 13 moves to the reagent sucking station and sucks the reagent at the reagent sucking station; subsequently, the dispensing module 13 moves to the dispensing station of the sample incubation module 14, and at the same time, the reaction cup on the sample incubation module 14 rotates to the dispensing station, and the dispensing module 13 adds the sucked reagent to the reaction cup of the sample incubation module 14 at the dispensing station.

The sample transport module 11, the cup feeding module 12, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16 and the sample detection module 17 of the blood analyzer 1 are arranged in the above manner, and are executed in the following order: the transfer module 16 transfers the empty reaction cup conveyed by the cup feeding module 12 to the placing position 14311 of the sample incubation module 14 at the cup taking and placing station, the sample conveying module 11 conveys the sample to be detected, the dispensing module 13 sucks the sample and then rotates to the dispensing station of the sample incubation module 14 to add the sample into the reaction cup of the sample incubation module 14, the dispensing module 13 sucks the reagent at the reagent sucking station of the first reagent storage mechanism 151 and adds the reagent into the reaction cup of the sample incubation module 14, the reaction cup of the sample incubation module 14 adds the reagent and detects the reaction cup with the added sample and reagent at intervals, and then the transfer module 16 transfers the reaction cup with the added sample and reagent into the detection module to detect, so as to obtain sample parameters. After the blood analyzer 1 performs the steps, the modular operation can be easily realized, the corresponding functions can be conveniently realized by adding modules on the blood analyzer 1, the expansion is easy, and meanwhile, the blood analyzer 1 can realize better functions, the operation efficiency is improved, and the use is convenient.

Also, referring to fig. 1, 4 and 5, the first reagent storage mechanism 151 includes a reagent mounting bracket 1511, a reagent pot 1512, a reagent disk 1513 provided in the reagent pot 1512, and a first reagent drive assembly 1514 for driving rotation of the reagent disk 1513. The reagent mounting bracket 1511 is supported and mounted on the blood analyzer 1, and the reagent pot 1512 is mounted on the reagent mounting bracket 1511. The reagent tray 1513 is used for storing reagents, and the reagent pan 1512 has a refrigerating function and can refrigerate the reagents on the reagent tray 1513; when the complete machine is in a shutdown state, the reagent can be supported to be continuously cooled to a lower temperature, so that the reagent stays overnight in the complete machine. The first reagent driving assembly 1514 is connected with the reagent disk 1513 to drive the reagent thereon to rotate to the reagent sucking station, so that the dispensing module 13 can suck the reagent conveniently. The first reagent driving assembly 1514 comprises a first reagent driving motor 15141 and a first reagent transmission part 15142, the first reagent transmission part 15142 is in transmission connection with the first reagent driving motor 15141 and the reagent tray 1513, and the first reagent driving motor 15141 drives the first reagent transmission part 15142 to rotate so as to drive the reagent tray 1513 to rotate in the reagent pot 1512, so that reagent is conveniently sucked.

The reagent tray 1513 comprises a tray 15131 arranged in a circular shape and a plurality of reagent racks 15132 arranged on the tray 15131, the tray 15131 is arranged at the bottom of the reagent pot 1512, the tray 15131 is in transmission connection with a first reagent transmission part 15142 in the reagent pot 1512, the first reagent transmission part 15142 can drive the tray 15131 to rotate in the reagent pot 1512, and meanwhile, the tray 15131 can also be directly separated from the first reagent transmission part 15142 along the axial direction, so that the reagent tray 1513 can be taken out. The plurality of reagent racks 15132 are enclosed on the tray 15131, and the reagent racks 15132 can be directly detached from the tray 15131 in the axial direction. The reagent rack 15132 is provided with a plurality of storage positions 151321 capable of storing reagent bottles with different specifications; when all the reagent bottles need to be taken out or put into the reagent tray 1513 at one time, only the tray 15131 needs to be taken out or put into the reagent tray 1513 directly along the axial direction; when a part of the reagent bottles need to be taken out or put in, if the reagent bottles needing to be operated are on one reagent rack 15132, the reagent rack 15132 only needs to be taken out or put in directly along the axial direction, if the reagent bottles needing to be operated are on different reagent racks 15132, the reagent bottles on the reagent rack 15132 can be taken out directly and independently or the corresponding reagent bottles can be put in the vacant positions of the reagent racks 15132, or the reagent bottles can be taken out or put in the reagent tray 1513 through the reagent racks 15132, so that the reagent bottles can be taken out or put in. Therefore, the reagent bottle taking and placing process can be considered, the reagent bottle is taken and placed integrally, is taken and placed in a partitioning mode and is taken and placed one by one, the flexibility is higher, and the overall efficiency of the automatic detection equipment is further improved.

Referring to fig. 1 and 3, further, the reagent storage module 15 further includes a second reagent storage mechanism 152 for storing a reagent, and the second reagent storage mechanism 152 is disposed between the first reagent storage mechanism 151 and the sample delivery module 11. The second reagent storage 152 is also used to store reagents for reacting with the sample, and the second reagent storage 152 can store reagents at normal temperature. The dispensing module 13 is capable of aspirating reagent from the second reagent storage mechanism 152 for addition to the sample incubation module 14. When the reagent to be added to the sample is stored in the second reagent storage mechanism 152, the second reagent storage mechanism 152 can move to the position where the dispensing module 13 is located, at this time, the second reagent storage mechanism 152 has a reagent taking station corresponding to the blood analyzer, and after the comprehensive needle mechanism 132 sucks the reagent in the reagent taking station, the comprehensive needle mechanism rotates to the dispensing station of the sample incubation module 14 to add the reagent to the reaction cup in the placing station 14311. When the reagent to be added to the sample is not present in the first reagent storage mechanism 151, the second reagent storage mechanism 152 may be controlled to move out of the apparatus, temporarily add a reagent bottle, move the second reagent storage mechanism 152 to the reagent taking station, and then perform the reagent sucking operation after filling.

Furthermore, the second reagent storage mechanism 152 can also store emergency samples, and the second reagent storage mechanism 152 can be moved to the dispensing module 13. The dispensing module 13 can aspirate the emergency sample in the second reagent storage mechanism 152 and add to the sample incubation module 14. When an emergency sample needs to be detected, the emergency sample is placed in the second reagent storage mechanism 152, the second reagent storage mechanism 152 drives the emergency sample to move to the separate injection module 13, the separate injection module 13 sucks the sample and transfers the sample to a reaction cup of the sample incubation module 14 for queue insertion detection, the detection time of the emergency sample is shortened, the position of the sample on the sample conveying module 11 is prevented from being adjusted in a stopping mode to convey the emergency sample, and the operation efficiency is improved.

The second reagent storage mechanism 152 includes a second reagent driving assembly disposed between the sample transport module 11 and the first reagent storage mechanism 151, and a reagent carriage disposed on the second reagent driving mechanism. The reagent conveying frame is provided with a plurality of reagent storage positions for placing the reagent and a plurality of emergency treatment sample storage positions for placing the emergency treatment sample, the plurality of reagent storage positions are arranged in a row, and the plurality of emergency treatment sample storage positions are arranged in a row. The second reagent drive assembly can drive the reagent conveying frame to move, so that the reagent conveying frame can move to the separated injection module 13, and reagents and samples can be conveniently sucked.

Referring to fig. 1 to 3, in order to support the sample transportation module 11, the cup feeding module 12, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16, and the sample detection module 17, the blood analyzer 1 further includes a test chamber 10, and the test chamber 10 has a placement chamber 104 and a test platform 101 covering the placement chamber 104. The test chamber 10 further includes a mounting frame 102 and a plurality of cover plates 102 surrounding the mounting frame 102. Preferably, the mounting frame 102 is rectangular, a plurality of cover plates 102 are disposed around the mounting frame 102, the testing platform 101 is mounted on the top of the mounting frame 102, and the cover plates 102, the mounting frame 102 and the testing platform 101 are disposed in the placing cavity 104. The sample conveying module 11, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16 and the sample detection module 17 are all located on the testing platform 101. The blood analyzer 1 further comprises a main control module 22 and a power supply module, the power supply module is electrically connected with the main control module 22, the main control module 22 is electrically connected with the sample conveying module 11, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16 and the sample detection module 17 respectively, and the main control module 22 and the power supply module are located in the placing cavity 104.

The test platform 101 can support various moving components thereon, and the test platform 101 can also separate the test box 10 into a space above the test platform 101 and a placing cavity 104 below the test platform 101, wherein the moving components of the blood analyzer 1, such as the sample conveying module 11, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16, and the sample detection module 17, are located on the test platform 101, and the non-moving components of the blood analyzer 1, such as the main control module 22 and the power supply module, are disposed in the placing cavity 104. Therefore, the structure of the blood analyzer 1 is neat and orderly, the limitation of the movement process caused by the complex structure is avoided, and the working efficiency is improved. The power supply module is used to power on and off the whole blood analyzer 1, so that the blood analyzer 1 can operate normally. The control module is used for controlling each component of the blood analyzer 1, so that each component can realize automatic operation, and the working efficiency of the blood analyzer 1 is improved.

The main control module 22 is electrically connected to the sample transportation module 11 to control the sample transportation module 11 to automatically transport the sample to be tested. The main control module 22 is electrically connected to the dispensing module 13, and specifically, the control module is electrically connected to the dispensing module 13, controls the dispensing module 13 to suck the sample at the sample conveying module 11 and add the sample at the dispensing station of the sample incubation module 14, and controls the dispensing module 13 to suck the reagent at the reagent sucking station exit of the first reagent storage mechanism 151 and add the reagent at the dispensing station of the sample incubation module 14. The main control module 22 is electrically connected to the sample incubation module 14 to control the placing position 14311 of the sample incubation module 14 to rotate to the cup taking and placing station, the dispensing station and the cup taking station, and at the same time, control the sample incubation module 14 to heat the sample for incubation. The main control module 22 is electrically connected with the first reagent storage mechanism 151 of the reagent storage module 15, and the main control module 22 can control the reagent at the corresponding position on the reagent storage module 15 to rotate to the reagent sucking station, and simultaneously can control the first reagent storage mechanism 151 to perform low-temperature cold storage on the reagent. The main control module 22 is electrically connected to the transfer module 16 to control the movement of the transfer module 16 between the cup taking and placing stations of the cup feeding module 12 and the sample incubation module 14 and the cup taking station and the sample detection module 17. The main control module 22 can also be electrically connected to the sample detection module 17 to control the sample detection module 17 to perform the detection operation. The main control module 22 is disposed in the placing cavity 104 of the testing box 10 to reduce the volume of each component, so as to greatly reduce the space occupied on the testing platform 101, so that the structure of the blood analyzer 1 is compact, and the miniaturization trend of the blood analyzer 1 is facilitated. Moreover, the main control module 22 integrates the control of each component, thereby facilitating the maintenance operation and reducing the cost and the failure rate of the machine.

In one embodiment of the present invention:

referring to fig. 1 to 3, the dispensing module 13 includes a puncture needle mechanism 131, an integrated needle mechanism 132, and a reagent needle mechanism 133. That is, the blood analyzer 1 of the present embodiment is a three-needle mechanism, and the puncture needle mechanism 131, the integrated needle mechanism 132, and the reagent needle mechanism 133 collectively achieve transfer of a sample and a reagent, and further achieve detection of the sample. The puncture needle mechanism 131 is used for aspirating and discharging a sample, the integrated needle mechanism 132 is used for aspirating and discharging a sample or a reagent, and the reagent needle mechanism 133 is used for aspirating and discharging a reagent.

The puncture needle mechanism 131 is located between the sample conveying module 11 and the sample incubation module 14, and the puncture needle mechanism 131 can transfer the sample conveyed by the sample conveying module 11 into the reaction cup of the sample incubation module 14. The puncture needle mechanism 131 rotates to the sample incubation module 14 after sucking the sample on the sample transport module 11, and adds the sucked sample to the reaction cup on the sample incubation module 14. The integrated needle mechanism 132 is located between the sample incubation module 14, the reagent storage module 15 and the sample transportation module 11, and the integrated needle mechanism 132 can transfer the reagent in the first reagent storage mechanism 151 into the reaction cup on the sample incubation module 14, or the integrated needle mechanism 132 can transfer the sample in the sample transportation module 11 into the reaction cup of the sample incubation module 14. The integrated needle mechanism 132 sucks the reagent on the reagent storage module 15 and then rotates to the sample incubation module 14 to add the sucked reagent into the reaction cup with the sample on the sample incubation module 14, and the integrated needle mechanism 132 can suck the sample on the sample conveying module 11 and then rotates to the sample incubation module 14 to add the sucked sample into the reaction cup on the sample incubation module 14. The reagent needle mechanism 133 is located between the sample incubation module 14, the reagent storage module 15 and the sample detection module 17, and the reagent needle mechanism 133 can transfer the reagent in the first reagent storage mechanism 151 into the reaction cup of the sample incubation module 14 or into the reaction cup of the sample detection module 17. The reagent needle mechanism 133 sucks the reagent from the first reagent storage mechanism 151 and rotates to the sample incubation module 14 to add the sucked reagent into the cuvette of the sample incubation module 14, or the reagent needle mechanism 133 sucks the reagent from the first reagent storage mechanism 151 and rotates to the sample detection module 17 to add the sucked reagent into the cuvette of the sample detection module 17.

And the separate injection station comprises a sample adding station, a first reagent adding station and a second reagent adding station, and the reagent sucking station comprises a first reagent sucking station and a second reagent sucking station. That is, the blood analyzer 1 is provided with a cup taking and placing station, a sample adding station, a first reagent adding station, a second reagent adding station, and a cup taking station around the sample incubation module 14, the blood analyzer 1 has a first reagent sucking station and a second reagent sucking station in the first reagent storage mechanism 151, and the blood analyzer 1 has a third reagent adding station in the sample detection module 17. The piercing needle mechanism 131 adds the aspirated sample to the reaction cup of the sample incubation module 14 at the sample application station. The integrated needle mechanism 132 adds the aspirated sample or reagent to a reaction cup on the sample incubation module 14 at the second reagent loading station. The reagent needle mechanism 133 adds the aspirated reagent to a reaction cup on the sample incubation module 14 at the first reagent adding station and adds the reagent to a reaction cup on the sample detection module 17 at the third reagent adding station. The integrated needle mechanism 132 aspirates reagent at the first reagent aspiration station and the reagent needle mechanism 133 aspirates reagent at the second reagent aspiration station. When a certain reagent needs to be added to a sample, the first reagent storage mechanism 151 rotates to enable the corresponding reagent to rotate to the first reagent sucking station or the second reagent sucking station, the comprehensive needle mechanism 132 sucks the reagent at the first reagent sucking station or the reagent needle mechanism 133 sucks the reagent at the second reagent sucking station, and then the sucked reagent is added into a reaction cup of the sample incubation module 14.

In another embodiment of the invention:

referring to fig. 21 to 23, the dispensing module 13 includes an integrated needle mechanism 132 and a reagent needle mechanism 133. That is, the blood analyzer 1 of the present embodiment is a two-needle mechanism, and the integrated needle mechanism 132 and the reagent needle mechanism 133 realize the transfer of the sample and the reagent together, and then realize the detection of the sample. The integrated needle mechanism 132 is used for aspirating and discharging a sample or a reagent, and the reagent needle mechanism 133 is used for aspirating and discharging a reagent.

The integrated needle mechanism 132 is located between the sample incubation module 14, the reagent storage module 15 and the sample delivery module 11, the integrated needle mechanism 132 is capable of transferring the sample in the sample delivery module 11 into the reaction cup of the sample incubation module 14, and the integrated needle mechanism 132 is also capable of transferring the reagent in the first reagent storage mechanism 151 into the reaction cup on the sample incubation module 14. The integrated needle mechanism 132 sucks a sample on the sample conveying module 11, rotates to the sample incubation module 14, and adds the sucked sample into a reaction cup on the sample incubation module 14, and the integrated needle mechanism 132 can suck a reagent on the reagent storage module 15, rotates to the sample incubation module 14, and adds the sucked reagent into a reaction cup with a sample on the sample incubation module 14. The reagent needle mechanism 133 is located between the sample incubation module 14, the reagent storage module 15 and the sample detection module 17, and the reagent needle mechanism 133 can transfer the reagent in the first reagent storage mechanism 151 to the sample incubation module 14 or the sample detection module 17. The reagent needle mechanism 133 sucks the reagent from the first reagent storage mechanism 151 and rotates to the sample incubation module 14 to add the sucked reagent into the cuvette of the sample incubation module 14, or the reagent needle mechanism 133 sucks the reagent from the first reagent storage mechanism 151 and rotates to the sample detection module 17 to add the sucked reagent into the cuvette of the sample detection module 17.

And the dispensing station comprises a sample adding station and a first reagent adding station, and the reagent sucking station comprises a first reagent sucking station and a second reagent sucking station. That is, the blood analyzer 1 is provided with a cup taking and placing station, a sample adding station, a first reagent adding station and a cup taking station surrounding the sample incubation module 14; the blood analyzer 1 has a first reagent sucking station and a second reagent sucking station in the first reagent storage unit 151, and the blood analyzer 1 has a third reagent adding station in the sample detection block 17. The integrated needle mechanism 132 can realize the operation of adding samples and the operation of adding reagents on the sample adding station. The integrated needle mechanism 132 adds the aspirated sample to a reaction cup on the sample incubation module 14 and the aspirated reagent to a reaction cup on the sample incubation module 14 at the loading station. The reagent needle mechanism 133 adds the aspirated reagent to a reaction cup on the sample incubation module 14 at the first reagent adding station and adds the reagent to a reaction cup on the sample detection module 17 at the third reagent adding station. The integrated needle mechanism 132 aspirates reagent at the first reagent aspiration station and the reagent needle mechanism 133 aspirates reagent at the second reagent aspiration station. When a certain reagent needs to be added to a sample, the first reagent storage mechanism 151 rotates to enable the corresponding reagent to rotate to the first reagent sucking station or the second reagent sucking station, the comprehensive needle mechanism 132 sucks the reagent at the first reagent sucking station or the reagent needle mechanism 133 sucks the reagent at the second reagent sucking station, and then the sucked reagent is added into the reaction cup of the sample incubation mechanism 143.

In yet another embodiment of the present invention:

referring to fig. 24, the dispensing module 13 includes a dispensing needle mechanism 134. That is, the blood analyzer 1 in the present embodiment is a needle mechanism, and the sample and the reagent are transferred by the dispensing needle mechanism 134 to detect the sample. The dispensing needle mechanism 134 is used for aspirating and discharging a sample or a reagent.

The dispensing needle mechanism 134 can transfer the sample from the sample transport module 11 to the reaction cup of the sample incubation module 14, and the dispensing module 13 can transfer the reagent from the first reagent storage mechanism 151 to the reaction cup of the sample incubation module 14 or the reaction cup of the sample detection module 17. It will be appreciated that the dispensing needle mechanism 134 needs to be positioned to move the dispensing needle mechanism 134 to the sample transport module 11, the reagent storage module 15, the sample incubation module 14, and the sample detection module 17 to facilitate the transfer of the sample and the reagent. Preferably, in the present embodiment, the dispensing needle mechanism 134 is located between the sample transportation module 11 and the first reagent storage mechanism 151, and the dispensing needle mechanism 134 can aspirate a sample on the sample transportation module 11, can aspirate a reagent in the first reagent storage mechanism 151, can add a sample and a reagent on the sample incubation module 14, and can add a reagent on the sample detection module 17.

Moreover, the dispensing station comprises a filling station, and the blood analyzer 1 is provided with a cup taking and placing station, a filling station and a cup taking station surrounding the sample incubation module 14; the blood analyzer 1 has a reagent sucking station at the first reagent storage mechanism 151, and the blood analyzer 1 has a third reagent adding station at the sample detection block 17. It can be understood that the station where the dispensing needle mechanism 134 adds the sample and the reagent on the sample incubation module 14 is at the same position, that is, the dispensing needle mechanism 134 can realize both the sample adding operation and the reagent adding operation on the sample adding station, so that the control of the dispensing needle mechanism 134 can be facilitated. The dispensing needle mechanism 134 adds the aspirated sample to a reaction cup on the sample incubation module 14 at the filling station, and adds the aspirated reagent to a reaction cup on the sample incubation module 14, and adds the reagent to a reaction cup on the sample detection module 17 at the third reagent adding station. When a certain reagent needs to be added to a sample, the first reagent storage mechanism 151 rotates to enable the corresponding reagent to rotate to the reagent sucking station, the reagent is sucked at the reagent sucking station through the dispensing needle mechanism 134, and then the sucked reagent is added into the reaction cup of the sample incubation mechanism 143 or the reaction cup of the sample detection module 17.

Referring to fig. 1, 6 and 7, as an embodiment, the sample transportation module 11 includes an automatic sample feeding mechanism for automatically transporting a plurality of containers containing samples arranged in a row on the sample rack. The automatic sample injection mechanism is provided with a puncture station and a non-puncture station, and the non-puncture station and the puncture station are arranged in sequence. It should be noted that, when the dispensing module 13 sucks a sample through the puncture needle mechanism 131 and the integrated needle mechanism 132, the puncture needle mechanism 131 can suck the sample in the container at the puncture station; the integrated needle mechanism 132 is capable of aspirating a sample in a container at a non-piercing station; when the dispensing module 13 sucks a sample by the integrated needle mechanism 132, the integrated needle mechanism 132 can suck the sample in the container at the non-piercing station; when the dispensing module 13 includes the dispensing needle mechanism 134, the dispensing needle mechanism 134 can aspirate a sample in a container at a non-puncture station; the distance between the non-piercing station and the piercing station is at least one time the spacing between two adjacent containers.

The main control module 22 includes a main controller and a scanning mechanism 113, the scanning mechanism 113 is used for scanning the detection code on the container with the sample conveyed by the sample conveying module 11, and the main controller is electrically connected with the scanning mechanism 113 and obtains the detection information of the sample test item in the container. Preferably, the scanning mechanism 113 is located at the sample incubation module 14 and is disposed towards the sample transport module 11. Of course, in other embodiments of the present invention, the scanning mechanism 113 may be located at other positions as long as the scanning mechanism 113 can detect the detection code on the container containing the sample. The scanning mechanism 113 is used in conjunction with an automated sample introduction mechanism of the sample transport device.

Specifically, the automatic sample feeding mechanism includes a detection assembly 111, a rotation assembly 112 and a sampling assembly 114, which are sequentially disposed. The detection component 111 is used for detecting whether the container exists or not; the rotating assembly 112 is used for rotating the container to align the detection code on the container with the scanning mechanism 113 so as to facilitate the scanning of the scanning mechanism 113; the piercing needle mechanism 131 is capable of aspirating a sample at the sampling assembly 114. The autosampler mechanism further includes a sample transport floor 118, a loading assembly 115, a transport assembly (not shown), an unloading assembly 116, and a turnaround assembly 117 disposed between the loading assembly 115 and the unloading assembly 116. The loading assembly 115 is used for placing a plurality of containers which are distributed in rows and are filled with samples, that is, a plurality of test tube racks are placed on the loading assembly 115, and a plurality of rows of test tubes filled with samples to be detected are placed on each test tube rack. The unloading assembly 116 is used to recover samples that have completed testing. The conveying assembly is used for realizing automatic conveying of the test tube rack, so that the test tube rack runs among the loading assembly 115, the detection assembly 111, the rotating assembly 112, the sampling assembly 114 and the unloading assembly 116. The carousel assembly 117 serves to return the test tubes loaded with samples in the unloading assembly 116 to the loading assembly 115. The sample transport floor 118 serves as a support. The loading assembly 115, the conveying assembly, the detecting assembly 111, the rotating assembly 112, the sampling assembly 114, the unloading assembly 116 and the rotating assembly 117 are all disposed on a sample conveying bottom plate 118, the automatic sample feeding mechanism further includes a sample conveying top plate 119, and the sample conveying top plate 119 is covered on the sample conveying bottom plate 118, so that each transmission component of the sample conveying module 11 is hidden between the sample conveying bottom plate 118 and the sample conveying top plate 119, and operation safety is prevented from being affected by touching of an operator. The sample conveying top plate 119 is provided with a card swiping component 1191, and the card swiping component 1191 can control the sample conveying module 11 to start the automatic sample conveying operation. Of course, in other embodiments of the present invention, the detecting component 111 and the scanning mechanism 113 may also be a single component, that is, a detecting and scanning component, which can detect whether there is a test tube and scan a detection code of the test tube.

Optionally, the loading assembly 115 includes a loading driving motor and a loading pushing member, and the loading driving motor is connected to the loading pushing member so that the loading pushing member pushes the test tube rack onto the conveying assembly. The conveying assembly comprises a conveying driving motor and a conveying part, the conveying driving motor is connected with the conveying part, and the conveying driving motor can drive the conveying part to move in a stepping mode, so that the distance between the two test tubes is the distance between the test tube rack and the test tube rack in one step. Detection component 111 is used for detecting the container and test tube detects, and detection component 111 can detect whether have the test tube in the test-tube rack, can also detect whether the test tube has the test tube cap simultaneously, if there is the test tube cap, then absorbs reagent through pjncture needle mechanism 131, if there is not the test tube cap, then absorbs reagent through synthetic needle mechanism 132 or branch injection needle mechanism 134. The rotating assembly 112 is correspondingly arranged with the scanning mechanism 113, so that the detection code on the test tube can be aligned with the scanning mechanism 113, and the detection item information of the sample can be conveniently acquired. When the detection code on the test tube does not correspond to the scanning mechanism 113, the rotating assembly 112 can rotate the test tube, so that the detection code of the test tube faces the scanning mechanism 113, and the sample information is conveniently recorded. Rotating assembly 112 includes test tube rotary drive motor and test tube rotary drive part, and test tube rotary drive motor is connected with test tube rotary drive part, rotates through test tube drive part drive test tube. The sampling assembly 114 has a sampling plate with sampling holes, the test tube moves to the sampling plate, the sampling holes are opposite to the test tube, and the puncture needle mechanism 131 can extend into the test tube to suck the sample. The unloading assembly 116 includes an unloading driving motor and an unloading pushing component, and the unloading driving motor is connected to the unloading pushing component so that the unloading pushing component pushes the test tube rack out of the conveying assembly. The unloading pushing means also enables the rack to be pushed onto the turnaround assembly 117 when a sample needs to be reviewed. The rotation assembly 117 comprises a rotation driving motor and a rotation pushing component, the rotation driving motor is connected with the rotation pushing component, and the test tube rack is pushed back to the loading assembly 115 from the unloading assembly 116 through the rotation pushing component to be retested. The conveying assembly can realize automatic conveying of the test tube rack among the detection assembly 111, the rotating assembly 112 and the sampling assembly 114, automatic conveying of samples is realized, and efficiency is improved.

When the automatic sample introduction mechanism conveys samples, a plurality of test tube racks are arranged in the loading assembly 115 in rows, and a plurality of test tubes containing the samples are placed on each test tube rack in rows. The loading assembly 115 can push the racks onto the transport assembly; then, the conveying assembly moves to move the test tube on the test tube rack to the detection assembly 111 for detection, and the scanning mechanism 113 is used for scanning and extracting item detection information of the sample; the transport assembly then moves the test tube to the sampling assembly 114, and the dispensing module 13 aspirates the sample in the test tube at the sampling assembly 114; the transport assembly then moves the test tubes to the unloading assembly 116 to recover the tested test tubes. When the sample needs to be retested, the rotary component 117 can send the sample detected in the unloading component 116 back to the loading component 115 for retesting, so that the detection efficiency of retesting the sample is greatly improved, the time is saved, and the convenience of operation is greatly improved.

Of course, in other embodiments of the present invention, the scanning station of the scanning mechanism 113 may also be located at the left side of the rotating assembly 112, that is, the test tube passes through the rotating assembly 112 and then passes through the scanning mechanism 113, the rotating assembly 112 rotates the detection code of the test tube to a desired position, and the conveying assembly drives the test tube to move to the scanning mechanism 113 for scanning. It should be noted that the distance of each movement of the conveying assembly is the distance between two test tubes, so that the test tubes can be conveniently moved to the corresponding operation assembly. Moreover, the rotating assembly 112 can only rotate the test tube with the test tube cap, so that the detection code is aligned with the position of the scanning mechanism 113; when not having the test tube cap on the test tube, rotating assembly 112 can not rotate the test tube that does not have the test tube cap, at this moment, in order to guarantee equipment normal operating, need the detection sign indicating number on the test tube need not to rotate and can face scanning mechanism 113, perhaps adopts the mode of artifical input detection sign indicating number for the sample can normal detection.

Furthermore, the detecting component 111 corresponds to a detecting station, the rotating component 112 corresponds to a rotating station, the scanning mechanism 113 has a scanning station on the automatic sampling mechanism, and the sampling component 114 corresponds to a puncturing station. The detection assembly 111 detects whether a test tube exists or not on a detection station, the rotating assembly 112 rotates the test tube on a rotating station, the scanning mechanism 113 scans the test tube on a scanning station, and the puncture needle mechanism 131 sucks a sample on a puncture sampling station of the sampling assembly 114. The distance between the detection station and the rotation station is at least one time of the distance between two adjacent containers, and the distance between the rotation station and the puncture station is at least one time of the distance between two adjacent containers. Therefore, the test tube can be conveniently moved to the detection station, the rotation station and the puncture station to carry out corresponding operation. Preferably, the distance between the piercing station and the rotation station is at least twice the spacing between two test tubes. When one of them test tube detected on the detection station like this, one of the other test tubes just in time was located rotatory station and is carried out rotation operation, raises the efficiency. When the test tube does not have the test tube cap, rotating assembly 112 can not put the requirement to the rotation that realizes the test tube on the test tube rack this moment for detection code on the test tube is towards scanning mechanism 113, makes things convenient for scanning mechanism 113 to acquire the project detection information of sample. Of course, it is also possible to place and transport test tubes without test tube caps on the reagent carriage of the second reagent storage mechanism 152, and at this time, the basic information of the sample can be acquired through manual entry.

Still further, the automatic sample injection mechanism has a non-puncture station, the rotation station and the detection station are sequentially arranged, and the integrated needle mechanism 132 and the dispensing needle mechanism 134 can suck samples in the non-puncture station containers. When the integrated needle mechanism 132 has a sufficient length to extend to the non-piercing station of the transport assembly, the sample in the test tube without the test tube cap at the non-piercing station can be drawn through the integrated needle mechanism 132. The transport assembly transports the test tube to a non-piercing station where the integrated needle mechanism 132 aspirates the sample in the test tube. The distance between the non-piercing station and the piercing station is at least one time the spacing between two adjacent containers. So can make things convenient for the test tube can just in time move and carry out corresponding operation on detecting station, rotatory station, the non-puncture station. Preferably, the distance between the non-piercing station and the rotation station is at least eight times the spacing between two test tubes. When one of them test tube detected on rotatory station like this, one in the other test tubes just in time was located the non-station of puncturing and carries out the sample operation, raises the efficiency. Of course, in other embodiments of the present invention, the distance between the non-puncturing station and the rotating station may also be a distance relationship between the other two test tubes, as long as it is ensured that when one of the test tubes is detected at the rotating station, one of the other test tubes is exactly located at the non-puncturing station for sampling operation.

It should be noted that the sample transport module 11 of the present invention is a general structure, and can be used in the blood analyzer 1 with three-needle structure, and at this time, the sample in the test tube of the transport module is sucked by the puncture needle mechanism 131 and the integrated needle mechanism 132; can be used in a two-needle blood analyzer 1, where the sample in the test tube of the present transport module is drawn through the integrated needle mechanism 132; it is also possible to use the blood analyzer 1 having a needle structure in which the sample in the test tube of the sample transport module 11 is sucked by the dispensing needle mechanism 134.

When the blood analyzer 1 of the present invention adopts a three-pin structure, when a capped test tube and a uncapped test tube exist in the test tube conveyed by the sample conveying module 11, the detecting assembly 111 can detect whether the test tube exists on the test tube rack, and can detect whether a test tube cap exists on the test tube. Thus, the conveying assembly can convey the test tube with the test tube cap to the puncture station, and the sample in the test tube is sucked by the puncture needle mechanism 131; the transport assembly transports the uncapped test tube to the non-piercing station where the sample is drawn through the integrated needle mechanism 132. of course, in other embodiments of the present invention, the transport assembly can transport the uncapped test tube to the piercing station where the sample is drawn through the piercing needle mechanism 131. Preferably, the sampling assembly 114 includes a baffle, one end of the baffle is fixed on the sample conveying bottom plate 118, the other end is horizontally disposed, a through hole is disposed on the horizontal end of the baffle, and the puncture needle mechanism 131 extends into the test tube through the through hole to suck the sample. After the absorption is completed, the separation blade can drive the test tube to rise together when taking out the capped test tube, and the horizontal end of the separation blade can limit the position of the test tube, so that the absorption operation is guaranteed to be reliable. In this embodiment, the blood analyzer 1 can only suck the sample of the sample transport module 11 through the puncture needle mechanism 131, and the blood analyzer 1 can also suck the sample of the sample transport module 11 through the puncture needle mechanism 131 and the integrated needle mechanism 132 together to improve the operation efficiency, and at this time, the interference problem between the puncture needle mechanism 131 and the integrated needle mechanism 132 needs to be avoided.

When the blood analyzer 1 of the present invention adopts the two-needle structure, the blood analyzer 1 cannot absorb the sample in the test tube with the test tube cap, but only absorbs the sample in the test tube without the test tube cap, and the detection assembly 111 detects whether the test tube cap exists on the test tube rack. In this manner, the transport assembly transports the uncapped test tubes to the non-piercing station where the integrated needle mechanism 132 aspirates the sample from the uncapped test tubes and transfers the sample to the sample incubation module 14. Moreover, the detection codes on the test tubes without the test tube caps have uniform directions, so that the scanning mechanism 113 can conveniently acquire the information of the sample needing the test items.

When the blood analyzer 1 of the present invention adopts a needle structure, the blood analyzer 1 cannot absorb the sample in the test tube with the test tube cap, but only absorbs the sample in the test tube without the test tube cap, and the detection assembly 111 detects whether the test tube cap exists on the test tube rack. Thus, the transport assembly transports the uncapped test tube to the non-piercing station where the dispensing needle mechanism 134 aspirates the sample from the uncapped test tube and transfers it to the sample incubation module 14. Moreover, the detection codes on the test tubes without the test tube caps have uniform directions, so that the scanning mechanism 113 can conveniently acquire the information of the sample needing the test items.

Of course, the sample transport module 11 of the present invention can also be connected with other in vitro diagnostic products, the sample transport module 11 is removed, and the blood analyzer 1 and other in vitro diagnostic devices are connected by a sample injector to form a test line. The dispensing module 13 can aspirate samples on the sample injector, so that the sample transport module 11 of the present invention has a wide application range.

Referring to fig. 1-3, as an example, the transfer module 16 includes a first transfer mechanism 161 and a second transfer mechanism 162. The first transfer mechanism 161 is movably disposed above the cup entering module 12 and the sample incubation module 14, and the first transfer mechanism 161 is used for transferring the reaction cups transferred by the cup entering module 12 to the sample incubation module 14. The second transfer mechanism 162 is movably disposed above the sample incubation module 14 and the sample detection module 17, and the second transfer mechanism 162 is used for transferring the reaction cup on the sample incubation module 14 to the sample detection module 17 after adding the sample and the reagent. In order to improve the transfer efficiency of the cuvettes, the blood analyzer 1 of the present invention employs two transfer members, namely, a first transfer mechanism 161 and a second transfer mechanism 162, wherein the empty cuvettes are transferred by the first transfer mechanism 161, and the cuvettes to which reagents and samples are added are transferred by the second transfer mechanism 162, so that the first transfer mechanism 161 and the second transfer mechanism 162 have their respective functions, thereby improving the working efficiency of the blood analyzer 1.

Moreover, the sample detection module 17 in the blood analyzer 1 of the present invention can perform different types of detection on the sample to obtain different performance parameters. The sample detection module 17 can perform data acquisition and result output of various parameter measurements. The sample detection module 17 of this embodiment is capable of supporting the measurement of a sample by a coagulation method, an immunoturbidimetry method, and a chromogenic substrate method. Specifically, the sample detection module 17 includes a paramagnetic particle detection mechanism 171 and an optical detection mechanism, the paramagnetic particle detection mechanism 171 performs a paramagnetic particle detection on the sample, and the optical detection mechanism performs an optical detection on the sample. The magnetic bead method detection unit 171 is disposed side by side with the optical method detection unit, so that the transfer of the cuvette can be facilitated. The magnetic bead detection unit 171 and the optical detection unit can detect a sample by adding different reagents thereto, and thus have a wide range of applications. In one embodiment of the present invention, the first transfer module 16 transfers the empty reaction cup delivered by the cup entering module 12 to the placement site 14311 of the sample incubation module 14; the second transfer mechanism 162 can transfer the cuvette to which the sample and the reagent are added in the sample incubation module 14 to the optical detection mechanism or the magnetic bead detection mechanism 171. That is, the first transfer mechanism 161 and the second transfer mechanism 162 transport and transfer the cuvettes. In another embodiment of the present invention, the transfer module 16 can transfer the reaction cup, to which the sample and the reagent are added, on the sample incubation module 14 to the optical detection mechanism or the magnetic bead detection mechanism 171, that is, the transfer module 16 can adopt only one transfer mechanism and can also meet the requirement of transferring and transferring the reaction cup.

Meanwhile, in order to avoid the first transfer mechanism 161 from being idle when the empty cuvette is not transferred, the first transfer mechanism 161 cannot be fully used, and the blood analyzer 1 cannot perform a better function. Therefore, the number of the optical detection mechanisms in the blood analyzer 1 of the present invention is two, so that the first transfer mechanism 161 can transfer the cuvette to which the sample and the reagent have been added to one of the optical detection mechanisms when it is idle, and the second transfer mechanism 162 still transfers the cuvette to which the sample and the reagent have been added to the other of the optical detection mechanism and the magnetic bead detection mechanism 171, and the first transfer mechanism 161 and the second transfer mechanism 162 are fully utilized to improve the utilization rate, thereby improving the working efficiency of the blood analyzer 1. Moreover, the two optical detection mechanisms are separately arranged, so that the situation that a larger optical detection mechanism cannot be placed can be avoided, the area for optical detection is increased, and the space on the test platform 101 is reasonably utilized. Optionally, the two optical detection mechanisms can also implement setting different optical detection positions.

Specifically, the two optical detection means are a first optical detection means 172 and a second optical detection means 173, respectively, and the magnetic bead detection means 171, the second optical detection means 173, and the first optical detection means 172 are provided in this order. The first transfer mechanism 161 is movably disposed above the cup entering module 12, the sample incubation module 14 and the first optical detection mechanism 172, and the first transfer mechanism 161 is used for transferring the cuvettes transferred by the cup entering module 12 to the sample incubation module 14 and transferring the cuvettes added with the sample and the reagent on the sample incubation module 14 to the first optical detection mechanism 172. The second transfer mechanism 162 is movably disposed above the sample incubation module 14, the second optical detection mechanism 173, and the magnetic bead detection mechanism 171, and the second transfer mechanism 162 is used to transfer the cuvette, to which the sample and the reagent are added, in the sample incubation module 14 to the second optical detection mechanism 173 or the magnetic bead detection mechanism 171.

Referring to fig. 1 and 9, the magnetic bead method detection mechanism 171 includes a magnetic bead support frame 1711, a magnetic bead detection component, a magnetic bead detection seat 1712, and a magnetic bead control board 1713. The magnetic bead seat 1712 is disposed on the top of the magnetic bead support 1711, and the magnetic bead support 1711 supports the magnetic bead seat 1712 on the testing platform 101. The magnetic bead detection component is disposed in the magnetic bead detection seat 1712, the magnetic bead detection seat 1712 is provided with a plurality of magnetic bead detection positions 17121, the second transfer mechanism 162 can transfer the reaction cup, to which the sample and the reagent are added, in the sample incubation module 14 to the magnetic bead detection position 17121 of the magnetic bead detection seat 1712, and then the magnetic bead detection component in the magnetic bead detection seat 1712 is used for performing magnetic bead method detection on the sample to obtain parameters of the sample. The magnetic bead control plate 1713 is disposed below the magnetic bead detection seat 1712, and the magnetic bead control plate 1713 is electrically connected to the magnetic bead detection unit to control the magnetic bead method detection mechanism 171 to perform magnetic bead method detection.

The plurality of magnetic bead detection sites 17121 are arranged in an arc shape in the magnetic bead detection base 1712, and the plurality of detection sites arranged in an arc shape correspond to the rotation locus of the reagent needle mechanism 133 or the dispensing needle mechanism 134. The blood analyzer 1 is provided with a third reagent adding station corresponding to the paramagnetic particle method detection mechanism 171, and the reagent needle mechanism 133 or the dispensing needle mechanism 134 sucks a reagent at the second reagent sucking station of the first reagent storage mechanism 151 and then rotates to the third reagent adding station of the paramagnetic particle method detection mechanism 171 to add the reagent. The plurality of magnetic bead detection sites 17121 arranged in an arc shape can facilitate the reagent needle mechanism 133 to rotate to the corresponding detection site for adding reagents. The third reagent adding station corresponds to a plurality of detection positions, and when the reagent needle mechanism 133 or the dispensing needle mechanism 134 rotates above the corresponding detection positions, the reagent needle mechanism 133 or the dispensing needle mechanism 134 can add a reagent into a reaction cup at the detection position. Alternatively, the magnetic bead detection holder 1712 has four magnetic bead detection sites 17121, and the four magnetic bead detection sites 17121 are disposed on the arc-shaped movement locus of the reagent needle mechanism 133 or the dispensing needle mechanism 134.

Referring to fig. 1 and 10, the first optical detection mechanism 172 includes a first optical supporting frame 1721, a first optical detection component, a first optical detection seat 1722 and a first optical receiving plate 1723. The first optical inspection seat 1722 is disposed on the top of the first optical supporting frame 1721, and the first optical supporting frame 1721 supports the first optical inspection seat 1722 on the testing platform 101. The first optical detection component is disposed in the first optical detection seat 1722, the first optical detection seat 1722 is disposed with a plurality of first optical detection positions 17221, the first transfer mechanism 161 transfers the cuvette filled with the sample and the reagent to the first optical detection position 17221 on the first optical detection seat 1722 at the cup taking and placing position of the sample incubation mechanism 143, and then the sample is optically detected by the first optical detection component in the first optical detection seat 1722, so as to obtain parameters of the sample. The first optical receiving board 1723 is disposed on a side surface of the first optical detecting seat 1722, and the first optical receiving board 1723 is electrically connected to the first optical detecting component to control the first optical detecting mechanism 172 for optical detection. The first optical detection mechanism 172 further includes a first optical emission plate disposed on the first optical detection seat 1722 and opposite to the first optical receiving plate 1723.

Furthermore, the plurality of first optical detection sites 17221 are arranged in a linear manner to facilitate the transfer of the cuvettes by the first transfer mechanism 161 to the first optical detection site 17221 on the first optical detection seat 1722. Optionally, the number of the first optical detection positions 17221 is 6, and each of the 6 first optical detection positions 17221 is an immunoturbidimetric detection position, and shading needs to be considered to ensure that the detection structure is accurate. The second optical detection means 173 has the same structure as the first optical detection means 172, except that the second optical detection site of the second optical detection means 173 includes a chromogenic substrate reaction detection site and an immunoturbidimetric detection site, and the immunoturbidimetric detection site needs to be shielded from light. Of course, in other embodiments of the present invention, the number of the first optical detection sites 17221 on the first optical detection mechanism is the same as the number of the second optical detection sites on the second optical detection mechanism 173, the layout is also the same, and the chromogenic substrate reaction detection sites and the immunoturbidimetric detection sites can be arranged correspondingly, that is, one or some of the first optical detection sites 17221 are chromogenic substrate reaction detection sites, and the rest of the first optical detection sites 17221 are immunoturbidimetric detection sites; of course, the first optical detection site 17221 can be both chromogenic substrate reaction detection site or immunoturbidimetric detection site. Preferably, the first optical detection site 17221 comprises five immunoturbidimetric detection sites and one chromogenic substrate method detection site; the second optical detection site is arranged exactly the same as the first optical detection site 17221.

In one embodiment, the main control module 22 is electrically connected to the transfer module 16, and the main control module 22 controls the transfer module 16 to transfer the cuvettes on the sample incubation module 14 to the magnetic bead method detection mechanism 171 or the optical method detection mechanism according to the instruction. The main control module 22 can obtain item detection information to be executed by a sample in a cuvette, and then the main control module 22 controls the transfer module 16 to transfer an empty cuvette conveyed by the cuvette entering module 12 to the placing position 14311 of the sample incubation module 14, and the main control module 22 controls the dispensing module 13 to transfer a corresponding sample and various reagents required by the sample to execute item detection to a corresponding cuvette on the sample incubation module 14; subsequently, the main control module 22 controls the transfer module 16 to transfer the cuvette to which the sample and the reagent are added to the paramagnetic particle method detection mechanism 171 or the optical method detection mechanism according to the item detection information of the sample, that is, when the sample is detected by the paramagnetic particle method, the main control module 22 controls the transfer module 16 to transfer the cuvette to which the sample and the reagent are added to the paramagnetic particle method detection mechanism 171 according to the control instruction; when the sample is detected optically, the main control module 22 controls the transfer module 16 to transfer the cuvette to which the sample and the reagent are added to the optical detection mechanism according to the control instruction. Further, the main control module 22 can transfer the optically detected sample to the first optical detection mechanism 172 or the second optical detection mechanism 173 according to the actual use requirement. Therefore, the number of the detection samples can be increased, and after one of the reaction cups is fully placed, the other reaction cup can be continuously placed, so that the detection efficiency is improved.

Optionally, the main controller of the main control module 22 is further electrically connected to the dispensing module 13, the sample incubation module 14, the first reagent storage mechanism 151, the sample detection module 17, and the transfer module 16. The scanning mechanism 113 can transmit the acquired detection information of the sample test item to the main controller, the main controller controls the separate injection module 13 to transfer the sample conveyed by the sample conveying module 11 to the reaction cup of the sample incubation module 14 according to the detection information, controls the separate injection module 13 to transfer the corresponding reagent in the first reagent storage mechanism 151 to the reaction cup of the sample incubation module 14, and the main controller controls the transfer module 16 to move according to the detection information, so that the transfer mechanism transfers the reaction cup, in which the sample and the reagent are added, in the sample incubation module 14 to the sample detection module 17. The blood analyzer 1 of the present invention obtains sample item detection information by the scanning mechanism 113, and controls the transfer module 16, the dispensing module 13, the sample incubation module 14, the first reagent storage mechanism 151, and the sample detection module 17 by the main controller, so that each module cooperates with a flow required by the item detection information of the sample to realize the detection of the sample.

Further, when the detection information of the sample is the detection information of the magnetic bead method, the main control module 22 controls the movement of the transfer module 16, and transfers the reaction cup to the magnetic bead method detection mechanism 171 for the magnetic bead method detection. When the detection information of the sample is the optical detection information, the main control module 22 controls the movement of the transfer module 16, and transfers the reaction cup to the optical detection mechanism for optical detection.

The first optical detection means 173 and the second optical detection means 173 have an immunoturbidimetric detection site and a chromogenic substrate detection site. In order to further increase the diversified detection of the sample, when the optical detection information of the sample is the immunoturbidimetry detection information, the main control module 22 controls the movement of the transfer module 16 and transfers the reaction cup to the immunoturbidimetry detection position on the optical detection mechanism for optical detection; when the optical detection information of the sample is the detection information of the chromogenic substrate method, the main control module 22 controls the transfer module 16 to move, and transfers the reaction cup to the detection position of the chromogenic substrate method on the optical detection mechanism for optical detection. The blood analyzer 1 of the present invention performs different item tests on the sample by performing the magnetic bead test and the optical test on the sample, and performing the immunoturbidimetric test and the chromogenic substrate test by the optical test, so as to obtain different sample parameters.

The blood analyzer 1 of the present invention can realize the measurement of the functions of blood coagulation, anticoagulation and fibrinolysis systems, and can mainly carry out laboratory examination on thrombus and hemostasis, and the detection indexes of the molecular markers of the hemostasis and the thrombus are closely related to clinical various diseases, such as atherosclerosis, cardiovascular and cerebrovascular diseases, diabetes, arterial and venous thrombosis, thromboangiitis obliterans, pulmonary embolism, pregnancy hypertension syndrome, disseminated intravascular coagulation, hemolytic uremic syndrome, chronic obstructive pneumonia, etc. Of course, the blood analyzer 1 of the present invention can also be used for detecting parameters of samples other than blood samples. In addition, the laboratory test of the blood analyzer 1 according to the present invention for thrombus and hemostasis is usually performed by an optical method and a magnetic bead method, the magnetic bead method detection means 171 can detect a sample by the magnetic bead method, and the optical method detection means can detect a sample by the optical method. The magnetic bead detection unit 171 and the optical detection unit can detect a sample by adding different reagents thereto, and thus have a wide range of applications.

The magnetic bead method is a method for measuring the blood coagulation function based on the change of viscosity during the coagulation of plasma. The magnetic bead method detection mechanism 171 can generate a magnetic field during detection, the magnetic field can enable magnetic beads in the reaction cup to swing back and forth under the action of the magnetic field, the blood sample can be gradually coagulated after a reagent is added, the swing of the magnetic beads becomes smaller and smaller, and finally the magnetic beads are static, the blood coagulation time is measured through the time of the magnetic beads swinging back and forth, and then the viscosity of the blood sample is judged. For example, Activated Partial Thromboplastin Time (APTT), Prothrombin Time (PT), Thrombin Time (TT), Fibrinogen (FIB) and other test items are detected by a magnetic bead method and are provided with corresponding detection reagents.

When the sample is tested in the APTT test project, a test tube rack with the sample is loaded on the loading component 115 of the sample conveying module 11, and the sample is conveyed to a preset position through the conveying component; then the dispensing module 13 sucks the sample at a preset position, and the first transfer mechanism 161 transfers the reaction cup from the cup feeding module 12 to the sample incubation module 14; then the dispensing module 13 transfers the sample to a reaction cup of the sample incubation module 14, and while the sample is transferred, the conveying assembly of the sample conveying module 11 pushes the test tube rack which has sucked the sample out of the preset position and enters the unloading assembly 116; then, the dispensing module 13 sucks the mixed reagent in the reagent storage module 15 and transfers the mixed reagent into the reaction cup added with the sample in the sample incubation module 14, after the sample incubation module 14 incubates the sample for a preset time, the dispensing module 13 sucks the reaction reagent in the reagent storage module 15 and transfers the reaction reagent into the reaction cup added with the sample and the mixed reagent in the sample incubation module 14, and then the second transfer mechanism 162 transfers the reaction cup added with the sample and the reagent to the magnetic bead detection position 17121 of the magnetic bead method detection mechanism 171 for magnetic bead method detection; after the reaction is finished, the test result is obtained and compared with the standard result, if the test result is obviously deviated from the range of the standard result, the test tube rack containing the sample can be returned to the loading assembly 115 by the rotating assembly 117 for retesting, and the used reaction cup is discarded by the transferring module 16.

When a sample is tested in PT and TT test projects, a test tube rack with the sample is loaded on the loading assembly 115 of the sample conveying module 11, and the sample is conveyed to a preset position through the conveying assembly; then the dispensing module 13 sucks the sample at a preset position, and the first transfer mechanism 161 transfers the reaction cup from the cup feeding module 12 to the sample incubation module 14; then the dispensing module 13 transfers the sample to a reaction cup of the sample incubation module 14, and while the sample is transferred, the conveying assembly of the sample conveying module 11 pushes the test tube rack which has sucked the sample out of the preset position and enters the unloading assembly 116; then, the dispensing module 13 sucks a reaction reagent in the reagent storage module 15 and transfers the reaction reagent into a reaction cup added with a sample in the sample incubation module 14, and then the second transfer mechanism 162 transfers the reaction cup added with the sample and the reagent to the magnetic bead detection position 17121 of the magnetic bead method detection mechanism 171 for magnetic bead method detection; after the reaction is finished, the test result is obtained and compared with the standard result, if the test result is obviously deviated from the range of the standard result, the test tube rack containing the sample can be returned to the loading assembly 115 by the rotating assembly 117 for retesting, and the used reaction cup is discarded by the transferring module 16.

When a sample is subjected to FIB test item detection, a test tube rack loaded with the sample is loaded on a loading component 115 of the sample conveying module 11, and the sample is conveyed to a preset position through a conveying component; then the dispensing module 13 sucks the diluent in the reagent storage module 15, and the first transfer mechanism 161 transfers the reaction cup from the cup feeding module 12 to the sample incubation module 14; the dispensing module 13 then transfers the dilution to the reaction cup of the sample incubation module 14; then the dispensing module 13 sucks a sample at a preset position, and transfers the sample to a reaction cup of the sample incubation module 14, and while the sample is transferred, a conveying assembly of the sample conveying module 11 pushes the test tube rack which has sucked the sample out of the preset position to enter an unloading assembly 116; then, the sample incubation module 14 incubates the sample and the diluent in the reaction cup, after a preset time, the dispensing module 13 sucks the reaction reagent in the reagent storage module 15 and transfers the reaction reagent into the reaction cup added with the sample and the diluent in the sample incubation module 14, and then the second transfer mechanism 162 transfers the reaction cup added with the sample and the reagent to the magnetic bead detection position 17121 of the magnetic bead method detection mechanism 171 for magnetic bead method detection; after the reaction is finished, the test result is obtained and compared with the standard result, if the test result is obviously deviated from the range of the standard result, the test tube rack containing the sample can be returned to the loading assembly 115 by the rotating assembly 117 for retesting, and the used reaction cup is discarded by the transferring module 16.

The optical detection mechanism can detect a sample by an optical method, and will be described with reference to the sample as blood: the optical method is to measure the blood coagulation function according to the change of turbidity during the coagulation of blood plasma. The optical method of the optical method detection mechanism is mainly to detect the turbidity of blood in the coagulation process by adopting an immunoturbidimetry method and a substrate generation method so as to obtain corresponding parameters.

Immunoturbidimetry refers to an antigen-antibody binding dynamic assay method, whose basic principle is: when the antigen and antibody react in a special dilution system and the ratio is appropriate (generally, it is specified that the antibody is in excess), the formed soluble immune complex precipitates from the liquid phase under the action of a polymerization promoter (polyethylene glycol or the like) in the dilution system to form microparticles, and turbidity appears in the reaction solution. When the antibody concentration is fixed, the amount of the immunocomplex formed increases with the increase in the amount of the antigen in the sample, and the turbidity of the reaction solution also increases. The content of the antigen in the sample can be calculated by measuring the turbidity of the reaction solution and comparing with a series of standard products. For example, fibrin (ogen) degradation products (FDP) and plasma D-dimer (DD) can be detected by immunoturbidimetry and are provided with corresponding detection reagents.

When a sample is tested in an FDP test project, a test tube rack loaded with the sample is loaded on the loading assembly 115 of the sample conveying module 11, and the sample is conveyed to a preset position through the conveying assembly; then the dispensing module 13 sucks the sample at a preset position, and the first transfer mechanism 161 transfers the reaction cup from the cup feeding module 12 to the sample incubation module 14; then the dispensing module 13 transfers the sample to a reaction cup of the sample incubation module 14, and while the sample is transferred, the conveying assembly of the sample conveying module 11 pushes the test tube rack which has sucked the sample out of the preset position and enters the unloading assembly 116; then, the dispensing module 13 sucks the mixed reagent in the reagent storage module 15 and transfers the mixed reagent into the reaction cup added with the sample in the sample incubation module 14, after the sample incubation module 14 incubates the sample for a preset time, the dispensing module 13 sucks the reaction reagent in the reagent storage module 15 and transfers the reaction reagent into the reaction cup added with the sample and the mixed reagent in the sample incubation module 14, and then the first transfer mechanism 161 or the second transfer mechanism 162 transfers the reaction cup added with the sample and the reagent to the immunoturbidimetry detection position of the first optical detection mechanism 172 or the second optical detection mechanism 173 for optical detection; after the reaction is finished, the test result is obtained and compared with the standard result, if the test result is obviously deviated from the range of the standard result, the test tube rack containing the sample can be returned to the loading assembly 115 by the rotating assembly 117 for retesting, and the used reaction cup is discarded by the transferring module 16.

When a sample is detected in a DD test item, a test tube rack loaded with the sample is loaded on the loading assembly 115 of the sample conveying module 11, and the sample is conveyed to a preset position through the conveying assembly; then the dispensing module 13 sucks the diluent in the reagent storage module 15, and the first transfer mechanism 161 transfers the reaction cup from the cup feeding module 12 to the sample incubation module 14; the dispensing module 13 then transfers the dilution to the reaction cup of the sample incubation module 14; then the dispensing module 13 sucks a sample at a preset position, and transfers the sample to a reaction cup of the sample incubation module 14, and while the sample is transferred, a conveying assembly of the sample conveying module 11 pushes the test tube rack which has sucked the sample out of the preset position to enter an unloading assembly 116; then, the sample incubation module 14 incubates the sample and the diluent in the reaction cup, after a preset time, the dispensing module 13 sucks the reaction reagent in the reagent storage module 15 and transfers the reaction reagent into the reaction cup added with the sample and the diluent in the sample incubation module 14, and then the first transfer mechanism 161 or the second transfer mechanism 162 transfers the reaction cup added with the sample and the reagent to the immunoturbidimetry detection position of the first optical detection mechanism 172 or the second optical detection mechanism 173 for optical detection; after the reaction is finished, the test result is obtained and compared with the standard result, if the test result is obviously deviated from the range of the standard result, the test tube rack containing the sample can be returned to the loading assembly 115 by the rotating assembly 117 for retesting, and the used reaction cup is discarded by the transferring module 16.

The chromogenic substrate method is characterized in that a compound which can be catalytically cracked by the thromboplastin to be detected is artificially synthesized, a chromogenic material is connected to the compound, the chromogenic material can be dissociated in the detection process, so that color change occurs in a sample, and the activity of the detected thromboplastin can be calculated according to the color change. For example, an antithrombin III (AT III) test item can employ a chromogenic substrate method and a corresponding detection reagent.

When the sample is tested in the AT III test project, a test tube rack with the sample is loaded on the loading component 115 of the sample conveying module 11, and the sample is conveyed to a preset position through the conveying component; then the dispensing module 13 sucks the diluent in the reagent storage module 15, and the first transfer mechanism 161 transfers the reaction cup from the cup feeding module 12 to the sample incubation module 14; the dispensing module 13 then transfers the dilution to the reaction cup of the sample incubation module 14; then the dispensing module 13 sucks a sample at a preset position, and transfers the sample to a reaction cup of the sample incubation module 14, and while the sample is transferred, a conveying assembly of the sample conveying module 11 pushes the test tube rack which has sucked the sample out of the preset position to enter an unloading assembly 116; then, the dispensing module 13 sucks the mixed reagent in the reagent storage module 15 and transfers the mixed reagent into a reaction cup added with the sample and the diluent in the sample incubation module 14, the sample incubation module 14 incubates the sample in the reaction cup, after a preset time, the dispensing module 13 transfers the reaction cup added with the sample and the reagent to the chromogenic substrate method detection position of the first optical detection mechanism 172 or the second optical detection mechanism 173 for optical detection by the first transfer mechanism 161 or the second transfer mechanism 162 after the preset time; after the reaction is finished, the test result is obtained and compared with the standard result, if the test result is obviously deviated from the range of the standard result, the test tube rack containing the sample can be returned to the loading assembly 115 by the rotating assembly 117 for retesting, and the used reaction cup is discarded by the transferring module 16.

It should be noted that the preset positions of the present invention refer to a puncture station and a non-puncture station, the puncture needle mechanism 131 sucks a sample at the puncture station, and the integrated needle 1325 sucks a sample at the non-puncture station; the dispensing needle mechanism 134 aspirates a sample at the non-piercing station. In addition, the blood analyzer 1 of the present invention can detect the above items by using a one-needle mechanism, a two-needle mechanism, and a three-needle mechanism, but the operation form of the dispensing module 13 is different, and the use requirement can be satisfied by ensuring that the dispensing module 13 sucks the corresponding sample or reagent at the corresponding position by using the corresponding needle mechanism according to the above requirement.

The blood analyzer 1 of the present invention is default set to have seven test items of APTT, PT, TT, FIB, FDP, DD and ATIII, that is, the test items of APTT, PT, TT and FIB automatically go through the process of magnetic bead method detection, after the corresponding reagents are added, the second transfer mechanism 162 transfers the reaction cup to be detected to the magnetic bead detection position 17121 of the magnetic bead method detection mechanism 171 for magnetic bead method detection; the FDP, DD and ATIII test items automatically go through the optical detection process, after the corresponding reagents are added into the FDP and DD test items, the reaction cups needing to be subjected to the detection are transferred to the immunoturbidimetric detection positions of the first optical detection mechanism 172 or the second optical detection mechanism 173 by the first transfer mechanism 161 or the second transfer mechanism 162 to be subjected to the optical detection, and after the corresponding reagents are added into the ATIII test items, the reaction cups needing to be subjected to the detection are transferred to the chromogenic substrate detection positions of the first optical detection mechanism 172 or the second optical detection mechanism 173 by the first transfer mechanism 161 or the second transfer mechanism 162 to be subjected to the optical detection.

Moreover, when the sample is re-detected, the same test method is also needed for re-detection, for example, when the sample is subjected to the APTT item detection, if the detection result obviously deviates from the standard result, the result may be deviated due to the external environment such as lack of magnetic beads in the reaction cup, and at this time, the same method is also needed for re-detection of the sample, and the detection result is obtained again.

When a sample in the same test tube needs to be tested for multiple different test items, the dispensing module 13 needs to transfer the sample from the test tube of the sample transport module 11 to multiple reaction cups of the sample incubation module 14, where each reaction cup corresponds to one test item, add a corresponding reagent, and obtain corresponding parameters by using a corresponding testing method. Moreover, different parameters can be obtained by detecting the blood sample by the test items, so that the blood detection result is reliable and prepared, and the diagnosis is convenient.

When the blood analyzer 1 of the present invention performs a test, the scanning mechanism 113 can scan the detection code information on the test tube and transmit the information to the main controller, the main controller can obtain the information of the item to be tested of the sample, and then the main controller can control the detection method and the time used by the item to be tested to start different detection processes (such as an optical method and a magnetic bead method) and detection mechanisms (such as an optical method detection mechanism and a magnetic bead method detection mechanism 171), etc., so as to implement an automatic operation of sample detection. When the blood analyzer 1 of the present invention detects other test items such as blood coagulation factor VIII, the user can set the corresponding detection method and the corresponding reagent by himself/herself, so as to start different detection processes and detection mechanisms.

Referring to fig. 1 and 11, the first transfer mechanism 161 includes a first transfer mounting plate 1611, two first cup portions 1613 disposed opposite to each other, a first grasping and driving assembly 1612, a first elastic member 1614, a first transfer driving assembly 1615, and a first sliding rail 1616. The two first cup portions 1613 are disposed opposite to each other and can grip the reaction cup. The first grasping and driving assembly 1612 is used for grasping and releasing the reaction cup, and the first grasping and driving assembly 1612 is connected with at least one of the two first cup portions 1613 and drives the two first cup portions 1613 to move towards and/or away from each other. When the two first cup portions 1613 are moved toward each other, they serve to clamp the reaction cup. For releasing the reaction cups when the two first cup portions 1613 are moved apart. First transfer drive assembly 1615 is used for realizing transfer of reaction cups, first transfer drive assembly 1615 is connected with first grabbing drive assembly 1612, and first transfer drive assembly 1615 can drive first grabbing drive assembly 1612 and first grabbing cup portion 1613 connected with first grabbing drive assembly 1612 to move along first sliding track 1616, so that first transfer drive assembly 1615 can transfer reaction cups among cup feeding module 12, sample incubation module 14 and first optical method detection module through first grabbing cup portion 1613. The first transfer mounting plate 1611 serves as a support, the first slide rail 1616 is disposed on the first transfer support plate, and the first transfer mechanism 161 is mounted on the test platform 101 through the first transfer support plate.

The first grasping and driving assembly 1612 may employ a power source such as a motor, an electromagnet, a pneumatic cylinder, a hydraulic cylinder, etc., which can drive one of the two first grasping cup portions 1613 to move, or can drive the two first grasping cup portions 1613 to move at the same time. The first resilient member 1614 is disposed between the two first cup portions 1613, and movement of the two first cup portions 1613 towards and away from each other by the first grasping drive assembly 1612 causes the first resilient member 1614 to deform. At this time, the restoring force of the first elastic member 1614 is opposite to the movement causing the deformation thereof, that is, when the two first cup portions 1613 are moved toward each other to deform the first elastic member 1614, the restoring force of the first elastic member 1614 urges the two first cup portions 1613 to move away from each other. When the first elastic members 1614 are deformed when the two first cup portions 1613 move away from each other, the restoring force of the first elastic members 1614 urges the two first cup portions 1613 to move toward each other. The first transfer driving assembly 1615 includes a first transfer carriage, a first transfer driving motor and a first transfer transmission member, the first grabbing driving assembly 1612 is mounted on the first transfer carriage, and the first transfer carriage is further slidably mounted on the first sliding rail 1616, and the first transfer driving motor and the first transfer carriage are in transmission connection through the first transfer transmission member to drive the first transfer carriage to move along the first sliding rail 1616, so as to implement the transfer operation of the reaction cups.

Furthermore, the first transfer mechanism 161 further comprises a first ram, the first ram is located between the two first cup portions 1613, and the first ram is connected to a first grabbing drive assembly 1612, and the first grabbing drive assembly 1612 can drive the first ram to perform an extending or retracting motion. When the first ram is extended, the first ram can be extended between the two first cup portions 1613, so that the two first cup portions 1613 make a separate motion. When the first ram is retracted, the two first cup portions 1613 are moved toward each other by the first elastic member 1614.

Referring to fig. 1 and 12, the second transfer mechanism 162 includes a second transfer mounting plate 1621, two second cup portions 1623 disposed opposite to each other, a second grasping drive assembly 1622, a second elastic member, a second transfer drive assembly 1624, a second sliding track 1625, a third transfer drive assembly 1626, and a third sliding track 1627. The two second cup portions 1623 are disposed opposite to each other and can grip the reaction cup. The second grasping driving assembly 1622 is used for grasping and releasing the reaction cup, and the second grasping driving assembly 1622 is connected with at least two of the two second grasping cup portions 1623 to drive the two second grasping cup portions 1623 to move towards and/or away from each other. When the two second cup portions 1623 are moved toward each other, they are used to clamp the reaction cup. For releasing the reaction cup when the two second cup portions 1623 move apart. The second transfer driving assembly 1624 and the third transfer driving assembly 1626 are used for transferring a reaction cup, the second transfer driving assembly 1624 is slidably disposed on the second sliding track 1625, the third sliding track 1627 is disposed on the second transfer driving assembly 1624, the third transfer driving assembly 1626 is slidably disposed on the third sliding track 1627, the second grabbing driving assembly 1622 is disposed on the third transfer driving assembly 1626, the second transfer driving assembly 1624 can drive the third sliding track 1627 and the third transfer driving assembly 1626 on the third sliding track 1627 to move along the second sliding track 1625, the third transfer driving assembly 1626 can drive the second grabbing driving assembly 1622 and the second grabbing cup portion 1623 connected with the second grabbing driving assembly 1622 to move along the third sliding track 1627, so that the second transfer driving assembly 1624 and the third transfer driving assembly 1626 can drive the reaction cup to the sample incubation module 14 through the second grabbing cup portion 1623, The first optical detection module and the magnetic bead detection mechanism 171 are transferred therebetween. It should be noted that the extending direction of the second sliding track 1625 is perpendicular to the extending direction of the third sliding track 1627, and the extending direction of the second sliding track 1625 is parallel to the extending direction of the first sliding track 1616, so that the moving range of the second transfer mechanism 162 can be increased, meanwhile, interference to the first transfer mechanism 161 is not generated, the conveying range of the second transfer mechanism 162 is increased, and the operation efficiency is improved. The second transfer mounting plate 1621 serves as a support, the second slide rail 1625 is provided on the second transfer support plate, and the second transfer mechanism 162 is mounted on the test platform 101 through the second transfer support plate.

The second grasping drive assembly 1622 is disposed in substantially the same manner as the first grasping drive assembly 1612, and the second elastic member is disposed in substantially the same manner as the first elastic member 1614. Moreover, the second transfer mechanism 162 further includes a second lift pin, and the setting position and the control manner of the second lift pin are substantially the same as those of the first lift pin. Second transfer drive assembly 1624 and third transfer drive assembly 1626 are also configured substantially the same as first transfer drive assembly 1615, and the same or similar components will not be described in detail herein. Of course, in other embodiments of the present invention, the second grasping driving assembly 1622 and the first grasping driving assembly 1612 may be directly driven by an air cylinder or a hydraulic cylinder, or may be implemented by a motor in cooperation with a cam mechanism, a synchronous belt mechanism, a lead screw nut mechanism, or the like. Also, the form of the first and

second cup portions

1613 and 1623 is not limited as long as gripping of the reaction cup can be achieved. Preferably, both the first and

second cup portions

1613, 1623 are clamp blocks or jaws.

It should be noted that the sample incubation module 14 is a hub for the blood analyzer 1 of the present invention. Referring to fig. 1 to 3 and 13, the sample incubation module 14 drives the empty placement site 14311 to the cup taking and placing station, and the first transfer mechanism 161 can move to the cup taking and placing station and place the empty reaction cup in the placement site 14311 of the sample incubation module 14. The sample incubation module 14 drives the cuvettes to move to the cup taking and placing station, and the first transfer mechanism 161 can move to the cup taking and placing station and transfer the cuvettes added with the samples and the reagents to the first optical detection mechanism 172. The sample incubation module 14 drives the reaction cup to move to the cup taking station, and the second transfer mechanism 162 can move to the cup taking station and transfer the reaction cup added with the sample and the reagent to the second optical detection mechanism 173 or the magnetic bead detection mechanism 171. The sample incubation module 14 drives the reaction cup to move to the sample application station, and the puncture needle mechanism 131 moves to the sample application station and applies the sample to the reaction cup of the sample incubation module 14. The sample incubation module 14 moves the cuvette to the first reagent adding station, and the reagent needle mechanism 133 moves to the first reagent adding station and adds the reagent to the cuvette to which the sample is added. The sample incubation module 14 moves the cuvette to the second reagent adding station, and the integrated needle mechanism 132 moves to the second reagent adding station and adds the sample or reagent to the cuvette to which the sample is added.

Referring to fig. 1, 2 and 8, as an embodiment, the cup feeding module 12 includes a cup feeding support 121, a reaction cup storage mechanism 122, a reaction cup conveying mechanism 123 and a reaction cup transferring mechanism 124, wherein the reaction cup conveying mechanism 123 is disposed obliquely, the reaction cup storage mechanism 122 is disposed at a lower position of the reaction cup conveying mechanism 123, and the reaction cup transferring mechanism 124 is movable on the reaction cup conveying mechanism 123. The two ends of the cuvette conveying mechanism 123 are respectively provided with a lower position and an upper position, and the lower position is lower than the upper position. The reaction cup conveying mechanism 123 can drive the reaction cup transferring mechanism 124 to move between the lower position and the upper position of the reaction cup conveying mechanism 123, so as to realize the conveying of the reaction cups. Specifically, the cuvette conveying mechanism 123 conveys the cuvette transferring mechanism 124 to a lower position, the cuvette storage mechanism 122 conveys the cuvettes to the cuvette transferring mechanism 124, the cuvette conveying mechanism 123 conveys the cuvette transferring mechanism 124 to a higher position, so that the cuvette transferring mechanism 124 carries the cuvettes to move from the lower position to the higher position, and the first transferring mechanism 161 grabs the cuvettes on the cuvette transferring mechanism 124 at the higher position. The reaction cup transfer mechanism 124 has an empty cup taking station, and the first transfer mechanism 161 grasps the reaction cup at the empty cup taking station. The cup feeding module 12 is used to automatically feed empty cuvettes, so as to improve the feeding efficiency of cuvettes and further improve the operating efficiency of the blood analyzer 1. The cup feeding support 121 is used for supporting, the reaction cup storage mechanism 122, the reaction cup conveying mechanism 123 and the reaction cup transferring mechanism 124 are all mounted on the cup feeding support 121, and the reaction cup storage mechanism 122, the reaction cup conveying mechanism 123 and the reaction cup transferring mechanism 124 are supported on the test platform 101 by the cup feeding support 121 and are located on the side faces of the sample detection module 17 and the sample incubation module 14.

Empty cuvettes are stored in the cuvette storage unit 122, and the cuvette storage unit 122 includes a cuvette storage tray 1221 formed in a disk shape, to which cuvettes are fixed by a film and wound in a disk shape layer by layer on the cuvette storage tray 1221, and a film removing unit 1222 for removing the film from the cuvettes and transferring the cuvettes to the cuvette transfer unit 124. It should be noted that the empty cup taking station is a fixed and unchangeable position, and after the reaction cup transfer mechanism 124 is transferred from the lower position to the upper position by the reaction cup transfer mechanism 123, the empty reaction cup is located on the empty cup taking station; of course, the empty reaction cups may be conveyed to the empty cup removing station manually or by other mechanisms. The reaction cup conveying mechanism 123 adopts a synchronous belt structure or other similar structures such as a chain transmission structure to realize the conveying of the reaction cups. Moreover, the reaction cup conveying mechanism 123 is obliquely arranged, the lower position of the reaction cup conveying mechanism 123 is connected with the membrane removing part 1222, and the higher end of the reaction cup conveying mechanism 123 is connected with the reaction cup transferring mechanism 124 so as to convey the reaction cup to the cup removing position of the reaction cup transferring mechanism 124. Reaction cup conveying mechanism 123 that the slope set up can adopt the mode of slope setting to carry the reaction cup, avoids advancing the too high problem of cup module 12 overall height because of what reaction cup memory disc 1221 brought, reduces the overall height who advances cup module 12, and then reduces blood analyzer 1's overall height.

The cuvette transfer mechanism 124 includes a cuvette carrier 1241 and a blocking member 1242, the blocking member 1242 is movably disposed at a lower position of the cuvette conveying mechanism 123, and the cuvette carrier 1241 is movably disposed on the cuvette conveying mechanism 123. The cuvette carrier 1241 is used for carrying cuvettes, the cuvette carrier 1241 holds cuvettes at a lower position of the cuvette conveying mechanism 123, and then the cuvette conveying mechanism 123 drives the cuvette carrier 1241 to move to a higher position, at this time, the first transfer mechanism 161 can grab cuvettes at the empty cup taking position. The blocking member 1242 is used to block the stripping member 1222 so as to prevent the reaction cup on the stripping member 1222 from falling off when the reaction cup bearing member 1241 moves from the lower position to the upper position.

When the blood analyzer 1 delivers empty cuvettes, the cuvette storage tray 1221 rotates and releases cuvettes fixed on the film, the membrane removing unit 1222 removes the film from the cuvettes, and at the same time, the cuvette delivery mechanism 123 drives the cuvette carrier 1241 of the cuvette transfer mechanism 124 to move to a lower position, the membrane removing unit 1222 delivers the cuvettes onto the cuvette carrier 1241, and then the cuvette delivery mechanism 123 drives the cuvette carrier 1241 to move to a higher position; meanwhile, the blocking member 1242 of the cuvette transfer mechanism 124 blocks the membrane removing member 1222; at the moment, the reaction cup moves to an empty cup taking station; the transfer module 16 then transfers the reaction cups from the empty cup station to the pick and place cup station on the sample incubation module 14.

It should be noted that the sample incubation module 14 is a hub for the blood analyzer 1 of the present invention. Referring to fig. 1 to 3 and 13, the sample incubation module 14 drives the empty placement site 14311 to the cup taking and placing station, and the first transfer mechanism 161 can move to the cup taking and placing station and place the empty reaction cup in the placement site 14311 of the sample incubation module 14. The sample incubation module 14 drives the cuvettes to move to the cup taking and placing station, and the first transfer mechanism 161 can move to the cup taking and placing station and transfer the cuvettes added with the samples and the reagents to the first optical detection mechanism 172. The sample incubation module 14 drives the reaction cup to move to the cup taking station, and the second transfer mechanism 162 can move to the cup taking station and transfer the reaction cup added with the sample and the reagent to the second optical detection mechanism 173 or the magnetic bead detection mechanism 171. The sample incubation module 14 drives the reaction cup to move to the filling station, and the dispensing module 13 moves to the filling station and adds the sample or reagent into the reaction cup of the sample incubation module 14.

It should be further noted that the cup taking and placing station, the filling station and the cup taking station of the sample incubation module 14 are fixed positions on the sample incubation module 14, the dispensing module 13 always transfers the sample and the reagent to the sample incubation module 14 at a fixed position, and the transferring module 16 always transfers the reaction cup to the conveying or transferring position at a fixed position. When the sample incubation module 14 rotates, the cup taking and placing station, the filling station and the cup taking station do not move, and the sample incubation module 14 can drive the reaction cups in the placing positions 14311 on the sample incubation module to move to the corresponding stations so as to execute corresponding operations.

Specifically, the sample incubation module 14 includes an incubation support 141, an incubation driving mechanism 142, and a sample incubation mechanism 143, the incubation support 141 is used to support the sample incubation mechanism 143 on the testing platform 101, the incubation driving mechanism 142 is connected to the sample incubation mechanism 143, and drives the sample incubation mechanism 143 to rotate, so that the sample incubation mechanism 143 moves to the cup taking and placing station, the filling station, and the cup taking station, and performs corresponding operations. Specifically, the sample incubation mechanism 143 includes an incubation tray 1431, a heating element, and a thermal pan 1432. The incubation tray 1431 is rotatably provided in the warming pan 1432, and the heating member is provided between the incubation tray 1431 and the warming pan 1432. The incubation plate 1431 is provided with a plurality of placement positions 14311, the plurality of placement positions 14311 are sequentially arranged in a radial direction of the incubation plate 1431, and the reaction cup is placed in the placement position 14311 of the incubation plate 1431. When the incubation disc 1431 rotates, the sample and the reagent in the reaction cup can be subjected to the centrifugal force, so that the uniform mixing operation of the sample and the reagent is realized, the uniform mixing of the sample and the reagent is ensured, and the accurate detection result of the sample is ensured.

The incubation driving mechanism 142 includes an incubation driving motor 1421 and an incubation transmission component 1422, the incubation driving motor 1421 is fixed on the testing platform 101, the incubation transmission component 1422 is in transmission connection with the incubation disc 1431 and an output end of the incubation driving motor 1421, so that the incubation driving motor 1421 drives the incubation disc 1431 to rotate, the incubation disc 1431 drives the placement position 14311 thereon to rotate to the cup taking and placing station, the filling station and the cup taking station, and corresponding operations are executed. The incubation transmission part 1422 may be a synchronous belt transmission part or other parts capable of transmitting motion, such as a screw, a sprocket, etc.

Referring to fig. 1 to 3 and 13, when the blood analyzer 1 of the present invention employs a three-pin mechanism, the sample incubation module 14 drives the reaction cup to move to the sample application station, and the puncture needle mechanism 131 moves to the sample application station and applies the sample or the reagent to the reaction cup of the sample incubation module 14; the sample incubation module 14 drives the reaction cup to move to the first reagent adding station, and the reagent needle mechanism 133 moves to the first reagent adding station and adds the reagent into the reaction cup; the sample incubation module 14 moves the cuvette to the second reagent adding station, and the integrated needle mechanism 132 moves to the second reagent adding station and adds the sample or reagent to the cuvette to which the sample is added.

Specifically, when the blood analyzer 1 works, the first transfer mechanism 161 grabs an empty reaction cup at the cup taking and placing station and moves to the cup taking and placing station of the incubation tray 1431, meanwhile, the incubation tray 1431 drives the placing position 14311 thereon to rotate to the cup taking and placing station, and the first transfer mechanism 161 places the empty reaction cup in the placing position 14311 at the cup taking and placing station. The puncture needle mechanism 131 sucks a sample at the puncture station of the sample conveying module 11 and then rotates to the sample feeding station of the incubation disc 1431, meanwhile, the incubation disc 1431 drives the placing position 14311 on the incubation disc to move to the sample feeding station, and the puncture needle mechanism 131 feeds the sample sucked by the puncture needle mechanism into a reaction cup at the placing position 14311 of the sample feeding station. The integrated needle mechanism 132 sucks the reagent at the first reagent sucking station of the first reagent storage mechanism 151 and then rotates to the second reagent adding station of the incubation tray 1431, meanwhile, the incubation tray 1431 drives the reaction cup with the sample added at the placing station 14311 to move to the second reagent adding station, and the integrated needle mechanism 132 adds the reagent sucked at the second reagent adding station into the reaction cup with the sample added at the placing station 14311 at the second reagent adding station. The reagent needle mechanism 133 sucks reagent at the second reagent sucking station of the first reagent storage mechanism 151 and then rotates to the first reagent adding station of the incubation tray 1431, meanwhile, the incubation tray 1431 drives the cuvette with the sample added at the placing station 14311 to move to the first reagent adding station, and the reagent needle mechanism 133 adds the reagent sucked at the first reagent adding station into the cuvette with the sample added at the placing station 14311 at the first reagent adding station. The incubation plate 1431 drives the cuvette to which the sample and the reagent are added to move to the cup taking and placing station, and the first transfer mechanism 161 moves to the cup taking and placing station to grab the cuvette and transfer the cuvette to the first optical detection position 17221 of the first optical detection mechanism 172. The incubation plate 1431 drives the cuvette to which the sample and the reagent are added to move to the cup taking station, and the second transferring mechanism 162 moves to the cup taking station to grab the cuvette, and transfers the cuvette to the second optical detection position of the second optical detection mechanism 173 or to the magnetic bead detection position 17121 of the magnetic bead detection mechanism 171. When the integrated needle mechanism 132 is used to add a sample, after the integrated needle mechanism 132 sucks the sample at the non-puncturing position of the sample transport module 11, the integrated needle mechanism 132 moves to the second reagent adding position of the sample incubation module 14, at the same time, the incubation tray 1431 drives the hollow reaction cup at the placing position 14311 thereof to move to the second reagent adding position, and the integrated needle mechanism 132 adds the sample sucked by the integrated needle mechanism 132 to the reaction cup at the placing position 14311 at the second reagent adding position.

Referring to fig. 21 to 23, when the blood analyzer 1 of the present invention adopts a two-needle structure, the sample incubation module 14 drives the cuvette to move to the sample application station, and the integrated needle mechanism 132 moves to the sample application station and applies a sample or a reagent to the cuvette; the sample incubation module 14 moves the cuvette to the first reagent adding station, and the reagent needle mechanism 133 moves to the first reagent adding station and adds the reagent to the cuvette.

Specifically, when the blood analyzer 1 works, the first transfer mechanism 161 grabs an empty reaction cup at the cup taking and placing station and moves to the cup taking and placing station of the incubation tray 1431, meanwhile, the incubation tray 1431 drives the placing position 14311 thereon to rotate to the cup taking and placing station, and the first transfer mechanism 161 places the empty reaction cup in the placing position 14311 at the cup taking and placing station. The integrated needle mechanism 132 sucks a sample at the non-puncturing station of the sample conveying module 11 and then rotates to the sample feeding station of the incubation plate 1431, meanwhile, the incubation plate 1431 drives the placing position 14311 thereon to move to the sample feeding station, and the integrated needle mechanism 132 adds the sample sucked by the integrated needle mechanism 132 into a reaction cup at the placing position 14311 of the sample feeding station. The integrated needle mechanism 132 sucks the reagent at the first reagent sucking station of the first reagent storage mechanism 151 and then rotates to the sample adding station of the incubation plate 1431, meanwhile, the incubation plate 1431 drives the cuvette with the sample added at the placing station 14311 to move to the sample adding station, and the integrated needle mechanism 132 adds the reagent sucked at the sample adding station to the cuvette with the sample added at the placing station 14311 of the sample adding station. The reagent needle mechanism 133 sucks reagent at the second reagent sucking station of the first reagent storage mechanism 151 and then rotates to the first reagent adding station of the incubation tray 1431, meanwhile, the incubation tray 1431 drives the cuvette with the sample added at the placing station 14311 to move to the first reagent adding station, and the reagent needle mechanism 133 adds the reagent sucked at the first reagent adding station into the cuvette with the sample added at the placing station 14311 at the first reagent adding station. The incubation plate 1431 drives the cuvette to which the sample and the reagent are added to move to the cup taking and placing station, and the first transfer mechanism 161 moves to the cup taking and placing station to grab the cuvette and transfer the cuvette to the first optical detection position 17221 of the first optical detection mechanism 172. The incubation plate 1431 drives the cuvette to which the sample and the reagent are added to move to the cup taking station, and the second transferring mechanism 162 moves to the cup taking station to grab the cuvette, and transfers the cuvette to the second optical detection position of the second optical detection mechanism 173 or to the magnetic bead detection position 17121 of the magnetic bead detection mechanism 171.

Referring to fig. 24, when the blood analyzer 1 of the present invention adopts a needle structure, the sample incubation module 14 moves the cuvette to the filling station, and the dispensing needle mechanism 134 moves to the filling station and applies the sample or the reagent to the cuvette to which the sample is applied.

Specifically, when the blood analyzer 1 works, the first transfer mechanism 161 grabs an empty reaction cup at the cup taking and placing station and moves to the cup taking and placing station of the incubation tray 1431, meanwhile, the incubation tray 1431 drives the placing position 14311 thereon to rotate to the cup taking and placing station, and the first transfer mechanism 161 places the empty reaction cup in the placing position 14311 at the cup taking and placing station. The dispensing needle mechanism 134 sucks a sample at a non-puncture station of the sample conveying module 11, then rotates to a filling station of the incubation disc 1431, meanwhile, the incubation disc 1431 drives the placing position 14311 on the incubation disc to move to the filling station, and the dispensing needle mechanism 134 adds the sample sucked by the dispensing needle mechanism into a reaction cup at the placing position 14311 at the filling station. The dispensing needle mechanism 134 sucks the reagent at the reagent sucking station of the first reagent storage mechanism 151 and then rotates to the filling station of the incubation disc 1431, meanwhile, the incubation disc 1431 drives the reaction cup with the sample added at the placing station 14311 to move to the filling station, and the dispensing needle mechanism 134 adds the reagent sucked by the dispensing needle mechanism at the filling station into the reaction cup with the sample added at the placing station 14311 at the filling station. The incubation plate 1431 drives the cuvette to which the sample and the reagent are added to move to the cup taking and placing station, and the first transfer mechanism 161 moves to the cup taking and placing station to grab the cuvette and transfer the cuvette to the first optical detection position 17221 of the first optical detection mechanism 172. The incubation plate 1431 drives the cuvette to which the sample and the reagent are added to move to the cup taking station, and the second transferring mechanism 162 moves to the cup taking station to grab the cuvette, and transfers the cuvette to the second optical detection position of the second optical detection mechanism 173 or to the magnetic bead detection position 17121 of the magnetic bead detection mechanism 171.

Alternatively, referring to fig. 14, the blood analyzer 1 further includes a recovery module 18, and the recovery module 18 includes a first recovery mechanism and a second recovery mechanism, the first recovery mechanism is disposed on one side of the first optical detection mechanism 172, and the second recovery mechanism is disposed on one side of the second optical detection mechanism 173. The recovery module 18 is used for recovering the reaction cup after detection, so as to avoid environmental pollution caused by random flowing of the sample and the reagent in the reaction cup. Since the magnetic bead method detecting mechanism 171, the first optical method detecting mechanism 172, and the second optical method detecting mechanism 173 are implemented by the first transfer mechanism 161 and the second transfer mechanism 162, respectively, in order to discard the reaction cuvette that has been reacted in the sample detection module 17, the first transfer mechanism 161 and the second transfer mechanism 162 correspond to a cup discarding position, respectively. That is, the first transfer mechanism 161 may discard the cuvette detected by the first optical detection mechanism 172 to the first collection mechanism, and the second transfer mechanism 162 may discard the cuvette detected by the second optical detection mechanism 173 and the magnetic bead detection mechanism 171 to the second collection mechanism. When the blood analyzer 1 issues an emptying command, the first transfer mechanism 161 and the second transfer mechanism 162 can also transfer all the cuvettes on the sample incubation module 14 and the sample detection module 17 to the first recovery mechanism and the second recovery mechanism.

Specifically, the first recycling mechanism has a first recycling part and a first recycling storage box connected to the first recycling part, and the first recycling part has a first cup discarding opening 181. The first recovery part is disposed at a side of the first photo detection mechanism 172, and the first recovery storage box is disposed in the placing chamber 104 of the test cassette 10. The first transfer mechanism 161 can grasp the cuvette that has been detected by the first optical detection mechanism 172, and move to the first cup discarding port 181, so as to discard the cuvette. The discarded reaction cups enter the first recovery part through the first cup discarding opening 181 and then enter the first recovery storage box for temporary storage. When the first recycling storage box is filled with reaction cups, the first recycling storage box is taken out of the test box body 10, and the first recycling storage box is replaced or the reaction cups in the first recycling storage box are poured to a designated position.

The second collecting mechanism has a second collecting member having a second discard cup mouth 182 and a second collecting storage box connected to the second collecting member. The second recovery member is disposed at a side of the second optical detection mechanism 173, and the second recovery storage box is disposed in the placing cavity 104 of the test cassette 10. The second transfer mechanism 162 can grasp the cuvette that has been detected by the second optical detection mechanism 173, and move to the second discard mouth 182 to discard the cuvette. The discarded reaction cups enter the second recycling component through the second cup discarding opening 182 and then enter the second recycling storage box for temporary storage. When the second retrieval storing cassette is filled with cuvettes, the second retrieval storing cassette is taken out of the test chamber 10, and the second retrieval storing cassette is replaced or the cuvettes in the second retrieval storing cassette are inverted at a designated position. Of course, in other embodiments of the present invention, the first recycling storage box and the second recycling storage box may be an integral structure; the first recovery mechanism only comprises a first recovery part, the second recovery mechanism only comprises a second recovery part, the bottoms of the first recovery part and the second recovery part are respectively shielded by sealing plates, and when the first recovery part and the second recovery part need to be cleaned, the sealing plates are opened, so that the reaction cups in the first recovery part and the second recovery part fall into a designated storage box.

It should be noted that at least three of the first cup losing opening 181, the empty cup taking station, the cup taking and placing station, and the first optical detection mechanism 172 of the first recovery mechanism are arranged in a collinear manner and correspond to the movement track of the first transfer mechanism 161. Therefore, the movement of the first transfer mechanism 161 can be a linear reciprocating movement, the space occupied by the first transfer mechanism 161 is saved, the size of the whole blood analyzer 1 is reduced, meanwhile, the first transfer mechanism 161 can be linearly moved, the interference between the first transfer mechanism 161 and the second transfer mechanism 162 or other parts can be avoided, and the reliability of the movement is ensured. Moreover, the collinear arrangement of the first cup-losing opening 181, the cup-emptying station, the cup-taking and placing station and the first optical detection mechanism 172 can also facilitate the transfer of the reaction cup by the first transfer mechanism 161, thereby improving the operation efficiency. For example, the first cup throwing opening 181, the cup taking and emptying station, and the cup taking and placing station may be arranged in a collinear manner, the cup taking and emptying station, the first optical detection mechanism 172 may be arranged in a collinear manner, or all the stations may be arranged in a collinear manner.

Referring to fig. 1-3 and 15, optionally, the blood analyzer 1 further comprises a stirring module 19, and the stirring module 19 is disposed adjacent to the sample incubation module 14. The stirring module 19 is used to mix the sample and the reagent in the reaction cup of the sample incubation module 14. The blood analyzer 1 further has a stirring station corresponding to the sample incubation module 14, and the stirring module 19 stirs the cuvette after the sample and the reagent are added to the sample incubation module 14 at the stirring station. When the sample and the reagent in the reaction cup need to be mixed, the sample incubation mechanism 143 drives the reaction cup on the placing position 14311 to rotate to the stirring station, and the stirring module 19 can extend into the reaction cup to stir the sample and the reagent, so as to realize further mixing operation of the sample and the reagent.

Specifically, the stirring module 19 includes a first stirring support plate 191, a second stirring support plate 192, a first stirring driving mechanism 193, a second stirring driving mechanism 194, a stirring mounting mechanism 195, and a stirring rod 196. The first stirring support plate 191 and the second stirring support plate 192 can play a supporting role, the first stirring support plate 191 is fixed on the test platform 101, the first stirring drive mechanism 193 is installed on the first stirring support plate 191, the second stirring support plate 192 is movably arranged on the first stirring drive mechanism 193, and the second stirring drive mechanism 194 is installed on the second stirring support plate 192. The stirring mechanism 195 is mounted on the second stirring drive mechanism 194, and the stirring rod 196 is mounted on the stirring mechanism 195. The first stirring driving mechanism 193 can drive the second stirring supporting plate 192, the second stirring driving mechanism 194 thereon and the stirring installation mechanism 195 to reciprocate along the first direction, so that the stirring rod 196 reciprocates along the first direction. The second stirring driving mechanism 194 can drive the stirring rod 196 mounting mechanism to reciprocate along the second direction, so that the stirring rod 196 reciprocates along the second direction. The second direction is different from the first direction, for example, perpendicular to the first direction, and the first stirring driving mechanism 193 and the second stirring driving mechanism 194 drive the stirring rod 196 to move in different directions, so that the reaction solution can be sufficiently stirred. Preferably, the first stirring driving mechanism 193 and the second stirring driving mechanism 194 are synchronous belt mechanisms; of course, the first stirring driving mechanism 193 and the second stirring driving mechanism 194 may be screw transmission, belt transmission, etc.

The second stirring driving mechanism 194 comprises a second stirring driving motor 1941 and a second stirring transmission part 1942, the second stirring driving motor 1941 is disposed on the second stirring mounting plate, and the second stirring transmission part 1942 is in transmission connection with the second stirring driving motor 1941 and the stirring mounting mechanism 195 to drive the stirring rod 196 to reciprocate along the second direction. In the present embodiment, the first stirring drive mechanism 193 and the second stirring drive mechanism 194 have the same structure. Of course, the first stirring drive mechanism 193 may have a different structure from the second stirring drive mechanism 194. The stirring installation mechanism 195 comprises a stirring shaft 1951 and a stirring cantilever 1952 arranged on the stirring shaft 1951, one end of the stirring shaft 1951 is connected with the second stirring driving mechanism 194, the other end of the stirring shaft 1951 extends out in the vertical direction, one end of the stirring cantilever 1952 is installed on the extending end of the stirring shaft 1951, the other end of the stirring cantilever 1952 extends towards one end far away from the stirring shaft 1951, and the stirring rod 196 is installed on one end of the stirring cantilever 1952 far away from the stirring shaft 1951.

The hematology analyzer 1 of the present invention can further mix the sample and the reagent in the sample incubation module 14 through the stirring module 19, specifically, the first stirring driving mechanism 193 and the second stirring driving mechanism 194 drive the stirring installation mechanism 195 to move, so that the stirring rod 196 on the stirring installation mechanism 195 moves to the stirring station and extends into the reaction cup of the sample incubation module 14; subsequently, the first stirring driving mechanism 193 and the second stirring driving mechanism 194 move simultaneously, so that the stirring rod 196 moves in different directions, thereby achieving sufficient mixing of the sample and the reagent and ensuring uniform mixing.

Referring to fig. 15 and 20, fig. 20 is a schematic diagram illustrating a movement track of the stirring rod 196 in the stirring module 19 shown in fig. 15. Preferably, when the test item of the sample is detected by the magnetic bead method, the stirring bar 196 is stopped at the home position, and no stirring is performed. When the test item of the sample is optically inspected, the stirring rod 196 performs a two-dimensional movement in the vertical plane. Specifically, referring to fig. 20(a), when the test item of the sample is detected by the chromogenic substrate method using an optical method, the motion trajectory information of the stirring rod 196 is: after the stirring rod 196 extends into the reaction cup, the stirring rod first moves linearly in an oblique upward direction for a certain distance from a stirring starting point, then moves linearly upward in a vertical direction for a certain distance, then moves linearly back in a horizontal direction to be right above the stirring starting point, and then moves linearly downward in the vertical direction to return to the stirring starting point, so that a motion track of the stirring rod 196 is completed. Referring to fig. 20(b), when the test item of the sample is detected by the optical immunoturbidimetry, the motion trajectory information of the stirring rod 196 is: after the stirring rod 196 extends into the reaction cup, the stirring rod starts to move for a certain distance in a convex curve track in an oblique downward direction from a stirring starting point, and then moves back to the stirring starting point in a concave curve track in an oblique upward direction, so that a motion track of the stirring rod 196 is completed.

The inventors have studied and found that a trajectory of the two-dimensional movement of the stirring rod 196 in the vertical plane can generate a vortex over as long a distance as possible, and that the two-dimensional movement trajectories in the two vertical planes of fig. 20(a) and 20(b) are compared, and that the stirring efficiency in fig. 20(a) is higher and the bubbles generated in fig. 20(b) during the stirring are small, so that the trajectory of the stirring rod 196 shown in fig. 20(a) is suitable for the stirring of a reaction solution using a detection methodology insensitive to bubbles but strict with time, such as the above-mentioned chromogenic substrate method, and fig. 20(b) is suitable for the stirring of a reaction solution using a detection methodology sensitive to bubbles, such as the above-mentioned immunoturbidimetry.

In one embodiment of the present invention, the blood analyzer 1 transfers the sample and the reagent using the puncture needle mechanism 131, the integrated needle mechanism 132, and the reagent needle mechanism 133:

referring to fig. 1 to 3 and 16, the puncture needle mechanism 131 is used to puncture a sealed container to aspirate a sample, such as a test tube with a test tube cap; of course, the puncture needle mechanism 131 can also aspirate samples in open containers, such as test tubes without a test tube cap. The puncture needle mechanism 131 comprises a puncture needle support 1311, a puncture needle lifting drive assembly 1312, a puncture needle rotating drive assembly 1313, a puncture needle mounting assembly 1314 and a puncture needle 1315. The puncture needle support 1311 can play a supporting role, and the puncture needle support 1311 is fixedly mounted on the test platform 101 and is used for supporting the puncture needle lifting drive assembly 1312, the puncture needle rotating drive assembly 1313, the puncture needle mounting assembly 1314 and the puncture needle 1315 on the test platform 101. The puncture needle 1315 is used for sucking and discharging a sample, and the puncture needle mounting assembly 1314 is used for mounting the puncture needle 1315 and is mounted on the puncture needle support 1311. The puncture needle lifting driving assembly 1312 is connected with the puncture needle mounting assembly 1314, and the puncture needle lifting driving assembly 1312 can drive the puncture needle mounting assembly 1314 to do lifting movement, so as to drive the puncture needle 1315 to move to suck and discharge samples. The puncture needle rotation driving assembly 1313 is also connected to the puncture needle mounting assembly 1314, and the puncture needle rotation driving assembly 1313 can drive the puncture needle mounting assembly 1314 to perform a rotation motion, so that the puncture needle 1315 moves to the puncture station of the sample conveying module 11 or the sample loading station of the sample incubation module 14.

Specifically, the puncture needle elevation driving assembly 1312 includes a puncture needle elevation driving motor 13121 and a puncture needle elevation transmission member 13122. The puncture needle lifting driving motor 13121 is arranged on the puncture needle supporting frame 1311, the puncture needle lifting transmission part 13122 is arranged on the puncture needle lifting driving motor 13121 and the puncture needle installation component 1314, and the puncture needle lifting transmission part 13122 is in transmission connection with an output shaft of the puncture needle lifting driving motor 13121 and the puncture needle installation component 1314 so as to drive the puncture needle installation component 1314 to move up and down and further enable the puncture needle 1315 to move up and down. The puncture needle rotation drive unit 1313 includes a puncture needle rotation drive motor 13131 and a puncture needle rotation transmission member 13132. The puncture needle rotation driving motor 13131 is arranged on the puncture needle support frame 1311, the puncture needle rotation transmission part 13132 is arranged on the puncture needle rotation driving motor 13131 and the puncture needle installation component 1314, and the puncture needle rotation transmission part 13132 is in transmission connection with an output shaft of the puncture needle rotation driving motor 13131 and the puncture needle installation component 1314 so as to drive the puncture needle installation component 1314 to rotate and further drive the puncture needle 1315 to rotate. The puncture needle installation component 1314 comprises a puncture needle rotating shaft 13141 and a puncture needle rotating arm 13142, one end of the puncture needle rotating shaft 13141 is connected with the puncture needle rotating transmission part 13132 and the puncture needle lifting transmission part 13122, the other end of the puncture needle rotating shaft 13141 extends out in the vertical direction, one end of the puncture needle rotating arm 13142 is installed at the extending end of the puncture needle rotating shaft 13141, the other end of the puncture needle rotating arm 13142 extends towards the direction far away from the puncture needle rotating shaft 13141, and the puncture needle 1315 is arranged at one end of the puncture needle rotating arm 13142 far away from the puncture needle rotating shaft 131. The puncture needle lifting/lowering transmission part 13122 and the puncture needle rotation transmission part 13132 may be a synchronous belt transmission structure, or may be a chain transmission structure or the like to transmit motion.

When the puncture needle mechanism 131 transfers a sample, the puncture needle rotation driving assembly 1313 drives the puncture needle rotation shaft 13141 to drive the puncture needle rotation arm 13142 to rotate, and then the puncture needle rotation arm 13142 drives the puncture needle 1315 to rotate to a puncture station of the sample conveying module 11; the puncture lifting assembly drives the puncture needle rotating shaft 13141 to drive the puncture needle rotating arm 13142 to descend, then the puncture needle rotating arm 13142 drives the puncture needle 1315 to descend, and the puncture needle 1315 sucks a sample at a puncture station; after the sample is sucked, the puncture lifting assembly drives the puncture needle rotating shaft 13141 to drive the puncture needle rotating arm 13142 to ascend, and then the puncture needle rotating arm 13142 drives the puncture needle 1315 to ascend; the puncture needle rotation driving component 1313 drives the puncture needle rotating shaft 13141 to drive the puncture needle rotating arm 13142 to rotate, and then the puncture needle rotating arm 13142 drives the puncture needle 1315 to rotate to the sample adding station of the sample incubation module 14; the puncture lifting assembly drives the puncture needle rotating shaft 13141 to drive the puncture needle rotating arm 13142 to descend, then the puncture needle rotating arm 13142 drives the puncture needle 1315 to descend, and the puncture needle 1315 adds a sample to a reaction cup of the sample incubation module 14 at the sample adding station; after the sample is added, the puncture lifting assembly drives the puncture needle rotating shaft 13141 to drive the puncture needle rotating arm 13142 to ascend, and then the puncture needle rotating arm 13142 drives the puncture needle 1315 to ascend.

Referring to fig. 1-3 and 17, the integrated needle mechanism 132 is used to aspirate a sample, such as a test tube without a test tube cap, in an open container or to aspirate a reagent in a reagent bottle. The synthetic needle mechanism 132 includes a synthetic needle support 1321, a synthetic needle elevating driving component 1322, a synthetic needle rotating driving component 1323, a synthetic needle mounting component 1324, and a synthetic needle 1325 having a heating function. Of course, in other embodiments of the invention, the integrated needle 1325 may not have a heating function. The integrated needle support 1321 is capable of supporting, and the integrated needle support 1321 is fixedly installed on the testing platform 101, and is configured to support the integrated needle lifting driving component 1322, the integrated needle rotating driving component 1323, the integrated needle mounting component 1324, and the integrated needle 1325 on the testing platform 101. The integrated needle 1325 is used to suck and discharge the sample and the reagent, and the integrated needle mounting assembly 1324 is used to mount the integrated needle 1325 and is mounted on the integrated needle support 1321. The synthetic needle lifting driving component 1322 is connected with the synthetic needle mounting component 1324, and the synthetic needle lifting driving component 1322 can drive the synthetic needle mounting component 1324 to do lifting movement, so as to drive the synthetic needle 1325 to move to suck and discharge a sample or a reagent. The integrated needle rotational drive assembly 1323 is also coupled to the integrated needle mounting assembly 1324, and the integrated needle rotational drive assembly 1323 is capable of driving the integrated needle mounting assembly 1324 to perform a rotational movement, such that the integrated needle 1325 moves to the non-puncturing position of the sample transport module 11, the first reagent aspirating position of the first reagent storage mechanism 151, or the second reagent adding position of the sample incubation module 14.

Specifically, the integrated needle elevating driving assembly 1322 includes an integrated needle elevating driving motor 13221 and an integrated needle elevating transmission member 13222. The integrated needle lifting driving motor 13221 is installed on the integrated needle supporting frame 1321, the integrated needle lifting transmission part 13222 is installed on the integrated needle lifting driving motor 13221 and the integrated needle mounting component 1324, and the integrated needle lifting transmission part 13222 is in transmission connection with an output shaft of the integrated needle lifting driving motor 13221 and the integrated needle mounting component 1324 so as to drive the integrated needle mounting component 1324 to move up and down and further enable the integrated needle 1325 to move up and down. The integrated needle rotational drive assembly 1323 includes an integrated needle rotational drive motor 13231 and an integrated needle rotational transmission component 13232. The synthetic needle rotation driving motor 13231 is mounted on the synthetic needle support 1321, the synthetic needle rotation transmission component 13232 is mounted on the synthetic needle rotation driving motor 13231 and the synthetic needle mounting component 1324, and the synthetic needle rotation transmission component 13232 is in transmission connection with an output shaft of the synthetic needle rotation driving motor 13231 and the synthetic needle mounting component 1324 to drive the synthetic needle mounting component 1324 to rotate so as to drive the synthetic needle 1325 to rotate. The synthetic needle mounting assembly 1324 includes a synthetic needle rotating shaft 13241 and a synthetic needle rotating arm 13242, one end of the synthetic needle rotating shaft 13241 is connected with the synthetic needle rotating transmission part 13232 and the synthetic needle lifting transmission part 13222, the other end of the synthetic needle rotating shaft 13241 extends in the vertical direction, one end of the synthetic needle rotating arm 13242 is mounted on the extending end of the synthetic needle rotating shaft 13241, the other end of the synthetic needle rotating arm 13242 extends towards the direction far away from the synthetic needle rotating shaft 13241, and the synthetic needle 1325 is arranged on one end of the synthetic needle rotating arm 13242 far away from the synthetic needle rotating shaft 13241. The integrated needle lifting transmission component 13222 and the integrated needle rotation transmission component 13232 may be a synchronous belt transmission structure, and may also be a structure that realizes motion transmission, such as a chain transmission structure.

When the integrated needle mechanism 132 transfers the sample, the integrated needle lifting driving component 1322 drives the integrated needle rotating shaft 13241 to drive the integrated needle rotating arm 13242 to rotate, and then the integrated needle rotating arm 13242 drives the integrated needle 1325 to rotate to the non-puncture station of the sample conveying module 11; the synthetic needle lifting driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to descend, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to descend, and the synthetic needle 1325 sucks a sample at a non-puncture station; after the sample is sucked, the synthetic needle lifting driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to ascend, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to ascend; the synthetic needle rotation driving component 1323 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to rotate, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to rotate to the sample adding position of the sample incubation module 14; the synthetic needle lifting driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to descend, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to descend, and the synthetic needle 1325 adds a sample to a reaction cup of the sample incubation module 14 at the sample adding station; after the sample is added, the synthetic needle lifting/lowering driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to rise, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to rise.

When the integrated needle mechanism 132 transfers the reagent, the integrated needle lifting/lowering driving component 1322 drives the integrated needle rotating shaft 13241 to drive the integrated needle rotating arm 13242 to rotate, and then the integrated needle rotating arm 13242 drives the integrated needle 1325 to rotate to the first reagent sucking station of the first reagent storage mechanism 151; the synthetic needle lifting driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to descend, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to descend, and the synthetic needle 1325 absorbs the reagent at the first reagent absorbing station; after the reagent is sucked, the synthetic needle lifting driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to ascend, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to ascend; the synthetic needle rotation driving component 1323 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to rotate, and then the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to rotate to the sample adding position of the sample incubation module 14; the synthetic needle lifting driving component 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to descend, so that the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to descend, and the synthetic needle 1325 adds a reagent to a reaction cup of the sample incubation module 14 at a filling station; after the reagent is added, the synthetic needle lifting/lowering driving unit 1322 drives the synthetic needle rotating shaft 13241 to drive the synthetic needle rotating arm 13242 to rise, and the synthetic needle rotating arm 13242 drives the synthetic needle 1325 to rise.

The integrated needle mechanism 132 further includes an integrated needle heating control board and an integrated needle level detection board 1326, a heating member is provided in the integrated needle 1325, the integrated needle heating control board is electrically connected to the heating member, and the integrated needle heating control board controls the heating member to perform a heating operation. When the comprehensive needle 1325 sucks the refrigerated reagent in the first reagent storage mechanism 151, the heating part can heat the low-temperature reagent, and the low-temperature reagent is heated to a preset temperature and then added into the reaction cup of the sample incubation module 14 to ensure the reaction effect. When the integrated needle 1325 sucks the sample, the integrated needle heating control board no longer controls the heating part to heat, and the integrated needle 1325 transfers the normal-temperature sample into the reaction cup of the sample incubation module 14. When the integrated needle 1325 sucks the normal temperature reagent in the second reagent storage mechanism 152, the integrated needle heating control board no longer controls the heating part to heat, and the integrated needle 1325 transfers the normal temperature reagent into the reaction cup of the sample incubation module 14. The integrated needle 1325 is electrically connected to the integrated needle liquid level detection plate 1326. When the integrated needle 1325 sucks the reagent in the reagent bottle, the integrated needle liquid level detection plate 1326 can control the liquid level height of the reagent in the reagent bottle detected by the integrated needle 1325, and the influence on operation caused by the lack of the reagent is avoided.

Referring to fig. 1 to 3 and 18, the reagent needle mechanism 133 includes a reagent needle support frame 1331, a reagent needle driving assembly, a reagent needle mounting assembly 1334, and two reagent needles 1335, the reagent needle driving assembly is in transmission connection with the reagent needle mounting assembly 1334, and the two reagent needles 1335 are disposed on the reagent needle mounting assembly 1334. The reagent needle drive assembly drives the reagent needle mounting assembly 1334 to move so that the two reagent needles 1335 can move to the reagent uptake station of the reagent storage module 15, the first reagent loading station of the sample incubation module 14, and the third reagent loading station of the bead assay mechanism 171. The number of the reagent needle drive units is two, and the reagent needle drive units are a reagent needle elevation drive unit 1332 and a reagent needle rotation drive unit 1333. Reagent needle support 1331 may be configured to support reagent needle support 1331, and reagent needle support 1331 is fixedly mounted to test platform 101 for supporting reagent needle elevation drive assembly 1332, reagent needle rotation drive assembly 1333, reagent needle mounting assembly 1334, and reagent needle 1335 on test platform 101. Reagent needle 1335 is used to aspirate and discharge reagents, and reagent needle mounting assembly 1334 is used to mount reagent needle 1335 and to reagent needle support 1331. Reagent needle lift drive assembly 1332 is connected to reagent needle mounting assembly 1334, and reagent needle lift drive assembly 1332 can drive reagent needle mounting assembly 1334 to make a lifting motion, and then drive reagent needle 1335 to make a reagent sucking and discharging operation. The reagent needle rotary drive assembly 1333 is also coupled to the reagent needle mounting assembly 1334, and the reagent needle rotary drive assembly 1333 can drive the reagent needle mounting assembly 1334 to rotate, so that the reagent needle 1335 moves to the second reagent suction station of the first reagent storage mechanism 151, the first reagent loading station of the sample incubation module 14, or the third reagent loading station of the bead assay mechanism 171.

Specifically, reagent needle elevation drive assembly 1332 includes a reagent needle elevation drive motor 13321 and a reagent needle elevation drive mechanism 13322. A reagent needle lifting drive motor 13321 is mounted on the reagent needle support frame 1331, a reagent needle lifting transmission part 13322 is mounted on the reagent needle lifting drive motor 13321 and the reagent needle mounting assembly 1334, and the reagent needle lifting transmission part 13322 is in transmission connection with an output shaft of the reagent needle lifting drive motor 13321 and the reagent needle mounting assembly 1334 to drive the reagent needle mounting assembly 1334 to move up and down, so that the reagent needle 1335 moves up and down. Reagent needle rotation drive assembly 1333 includes a reagent needle rotation drive motor 13331 and a reagent needle rotation transmission feature 13332. The reagent needle rotation drive motor 13331 is mounted on the reagent needle support frame 1331, the reagent needle rotation transmission member 13332 is mounted on the reagent needle rotation drive motor 13331 and the reagent needle mounting assembly 1334, and the reagent needle rotation transmission member 13332 is drivingly connected to the output shaft of the reagent needle rotation drive motor 13331 and the reagent needle mounting assembly 1334 to drive the reagent needle mounting assembly 1334 to rotate and thus drive the reagent needle 1335 to rotate. The reagent needle mounting assembly 1334 includes a reagent needle rotation shaft 13341 and two reagent needle rotation arms 13342, one end of the reagent needle rotation shaft 13341 is connected to the reagent needle rotation transmission part 13332 and the reagent needle elevation transmission part 13322, the other end of the reagent needle rotation shaft 13341 extends in the vertical direction, one ends of the two reagent needle rotation arms 13342 are mounted on the extending end of the reagent needle rotation shaft 13341, the other ends of the two reagent needle rotation arms 13342 extend in the direction away from the reagent needle rotation shaft 13341, and the two reagent needles 1335 are respectively disposed on one ends of the two reagent needle rotation arms 13342 away from the reagent needle rotation shaft 13341. The reagent needle elevation transmission unit 13322 and the reagent needle rotation transmission unit 13332 may be a synchronous belt transmission structure, or may be a chain transmission structure or the like for transmitting motion.

Also, at least one reagent needle 1335 has a heating function. That is, reagent needle 1335 is capable of heating reagent in at least one reagent needle 1335 via a reagent needle 1335 heating assembly. The reagent needle 1335 heating assembly can heat the reagent of one of the reagent needles 1335 alone or both reagent needles 1335. Preferably, both reagent needles 1335 have a heating function, i.e., the reagent needle 1335 heating assembly includes two reagent needle 1335 heating elements, which are disposed in both reagent needles 1335, respectively, for heating reagent in reagent needles 1335. After the reagent in the reagent storage mechanism is sucked by the reagent needle 1335, the reagent is stored in the reagent needle 1335, the reagent needle 1335 heats the reagent by the heating part of the reagent needle 1335 inside, and after the temperature of the reagent reaches the preset temperature, the reagent is added into the reaction cup of the sample incubation module 14 or the reaction cup of the magnetic bead method detection mechanism 171, so that the reaction speed of the sample and the reagent is increased, and the analysis efficiency of the blood analyzer 1 is improved. Also, the reagent needle 1335 heats the component to quickly and accurately heat the reagent in the reagent needle 1335 and maintain the reagent at a predetermined temperature, so as to ensure the accuracy and efficiency of the test result.

Preferably, after one of the reagent needles 1335 has finished aspirating reagent, reagent needle rotary drive assembly 1333 drives reagent needle mounting assembly 1334 to rotate, and reagent needle 1335 can heat reagent therein at any position. Meanwhile, the other reagent needle 1335 may be rotated by the reagent needle rotation driving assembly 1333 to a second reagent sucking station in the first reagent storage mechanism 151 to suck reagent, to a first reagent adding station in the sample incubation module 14 to add reagent, to a third reagent adding station in the magnetic bead method detection mechanism 171 to spit out reagent, or may heat the reagent in the reagent needle 1335. That is, while one of the reagent needles 1335 is performing a heating operation, the other reagent needle 1335 may perform one or more of a reagent aspiration, reagent heating, and reagent expulsion operation. Similarly, one of the reagent needles 1335 may perform the above operations while the other reagent needle 1335 heats the reagent therein. That is, when the other reagent needle 1335 performs a heating operation, one of the reagent needles 1335 may perform one or more of operations of sucking a reagent, heating a reagent, and discharging a reagent.

When the reagent needle mechanism 133 transfers a sample, the reagent needle rotation driving assembly 1333 drives the reagent needle rotation shaft 13341 to drive the reagent needle rotation arm 13342 to rotate, and then the reagent needle rotation arm 13342 drives the reagent needle 1335 to rotate to the second reagent sucking station of the first reagent storage mechanism 151; the reagent needle lifting drive assembly 1332 drives the reagent needle rotating shaft 13341 to drive the reagent needle rotating arm 13342 to descend, and then the reagent needle rotating arm 13342 drives the reagent needle 1335 to descend, and the reagent needle 1335 sucks reagent at the second reagent sucking station; after reagent is sucked, the reagent needle lifting/lowering driving module 1332 drives the reagent needle rotation shaft 13341 to drive the reagent needle rotation arm 13342 to lift, and the reagent needle rotation arm 13342 drives the reagent needle 1335 to lift; the reagent needle rotation driving assembly 1333 drives the reagent needle rotation shaft 13341 to rotate the reagent needle rotation arm 13342, and then the reagent needle rotation arm 13342 drives the reagent needle 1335 to rotate to the first reagent adding station of the sample incubation module 14; the reagent needle lifting/lowering driving assembly 1332 drives the reagent needle rotating shaft 13341 to drive the reagent needle rotating arm 13342 to descend, and then the reagent needle rotating arm 13342 drives the reagent needle 1335 to descend, and the reagent needle 1335 adds reagent into the reaction cup of the sample incubation module 14 at the first reagent adding station; after reagent is added, the reagent needle lifting/lowering drive module 1332 drives the reagent needle rotation shaft 13341 to drive the reagent needle rotation arm 13342 to lift, and the reagent needle rotation arm 13342 drives the reagent needle 1335 to lift; alternatively, after the reagent is aspirated, the reagent needle rotation driving assembly 1333 drives the reagent needle rotation shaft 13341 to drive the reagent needle rotation arm 13342 to rotate, and then the reagent needle rotation arm 13342 drives the reagent needle 1335 to rotate to the third reagent adding station of the magnetic bead method detecting mechanism 171; the reagent needle lifting/lowering driving assembly 1332 drives the reagent needle rotation shaft 13341 to drive the reagent needle rotation arm 13342 to descend, and then the reagent needle rotation arm 13342 drives the reagent needle 1335 to descend, and the reagent needle 1335 adds reagent into the reaction cup of the magnetic bead method detection mechanism 171 at the third reagent adding station; after the reagent is added, the reagent needle elevation drive unit 1332 drives the reagent needle rotation shaft 13341 to raise the reagent needle rotation arm 13342, and the reagent needle rotation arm 13342 raises the reagent needle 1335.

The reagent needle mechanism 133 further includes a reagent needle heating control board 1336, the reagent needle 1335 having therein a heating element, the reagent needle heating control board 1336 being electrically connected to the heating element, the reagent needle heating control board 1336 controlling the heating element to perform a heating operation. When the reagent needle 1335 sucks the refrigerated reagent in the first reagent storage mechanism 151, the heating part can heat the reagent at a low temperature, and the heated reagent is added to the reaction cup of the sample incubation module 14 after being heated to a preset temperature, so as to ensure a reaction effect. Reagent needle mechanism 133 still includes reagent needle liquid level detection board 1337, and reagent needle liquid level detection board 1337 can detect the liquid level height of reagent in the reagent bottle of second reagent storage mechanism 152, and when the liquid level height of reagent was less than the default in the reagent bottle, reagent needle liquid level detection board 1337 can feed back the too little information of reagent, and suggestion operating personnel changes and adds the reagent, avoids the reagent not enough and influences the detection of sample, improves detection efficiency.

Further, the two reagent needle rotation arms 13342 are provided in a collinear manner, and the two reagent needles 1335 are provided at the ends of the two reagent needle rotation arms 13342, respectively. That is, the two reagent needles 1335 are disposed at an angle to the two reagent needle rotating arms 13342, and a space where the other reagent needle 1335 is located when one reagent needle 1335 performs operations of sucking and discharging a reagent is completely consistent with a space where the one reagent needle 1335 is located when the other reagent needle 1335 performs operations of sucking and discharging a reagent, so that design of a space for avoiding a position is facilitated, and thus, position setting and rotation control setting of the reagent needle mechanism 133 can be facilitated, and the overall structure of the blood analyzer 1 is optimized, so that the positions of the two reagent needles 1335 are more controllable, interference in a rotation process is avoided, and control of the reagent needle mechanism 133 is facilitated. Of course, the angle of the two reagent needles 1335 may be any angle between 30 ° and 180 °, so long as the position setting and the rotation control setting of the reagent needle mechanism 133 can be ensured, thereby preventing the reagent needles 1335 from colliding with the first reagent storage mechanism 151, the sample incubation module 14, and other structures during reagent aspiration and discharge, and improving the usability.

The respective reagent needles 1335 are cyclically executed in the order of arrangement of washing, reagent aspiration, reagent heating, and reagent discharge. While one of the reagent needles 1335 is heating reagent, the other reagent needle 1335 may perform one or more of a combination of washing, aspirating reagent, heating reagent, and spitting reagent. For convenience of description of reagent transfer of the reagent needle mechanism 133, two reagent needles 1335 are defined as a first reagent needle 13351 and a second reagent needle 13352, respectively, and the first reagent needle 13351 and the second reagent needle 13352 have the same structure. When the reagent needle mechanism 133 transfers the reagent, after the first reagent needle 13351 is cleaned, the reagent is sucked by rotating to the second reagent sucking station of the first reagent storage mechanism 151, after the reagent is sucked, the first reagent needle 13351 heats the reagent, meanwhile, after the second reagent needle 13352 is rotated to the corresponding position to perform the cleaning operation, the second reagent needle 13352 rotates to the second reagent sucking station of the first reagent storage mechanism 151 to suck the reagent, and then the second reagent needle 13352 heats the reagent; meanwhile, after the reagent in the first reagent needle 13351 reaches the preset temperature, the first reagent needle 13351 rotates to the first reagent adding position of the sample incubation module 14 or the third reagent adding position of the sample detection module 17 to add the reagent; after the first reagent needle 13351 is rotated to the corresponding position to perform the washing operation, the first reagent needle 13351 is rotated to the second reagent sucking station of the first reagent storage mechanism 151 to suck the reagent, and then the first reagent needle 13351 heats the reagent; at the same time, after the reagent in second reagent needle 13352 reaches the preset temperature, second reagent needle 13352 is rotated to the second reagent adding station of sample incubation module 14 or the third reagent adding station of sample testing module 17 to add reagent.

Of course, in other embodiments of the present invention, the reagent needle elevation drive assembly 1332 and the reagent needle rotation drive assembly 1333 may drive the rotation of the two reagent needles 1335 independently. That is, when the reagent needle lifting/lowering driving module 1332 and the reagent needle rotation driving module 1333 perform one or more of operations of sucking reagent, heating reagent, and discharging reagent while driving one of the reagent needles 1335 to rotate, the other reagent needle 1335 is in a stationary state to heat reagent; in contrast, when one or more of the operations of sucking, heating, and discharging the reagent are performed while one of the reagent needles 1335 is driven to rotate by the reagent needle elevation drive assembly 1332 and the reagent needle rotation drive assembly 1333, the other reagent needle 1335 heats the reagent.

Referring to fig. 1, the blood analyzer 1 further includes a cleaning module 20, and the cleaning module 20 includes a puncture needle cleaning mechanism 201 for cleaning the puncture needle 1315 of the puncture needle mechanism 131, an integrated needle cleaning mechanism 202 for cleaning the integrated needle 1325 of the integrated needle mechanism 132, a reagent needle cleaning mechanism 203 for cleaning the two reagent needles 1335 of the reagent needle mechanism 133, and an agitation bar cleaning mechanism 204 for cleaning the agitation bar 196 of the agitation module 19. The puncture needle 1315 needs to be cleaned before sucking the sample and after discharging the sample, so that the puncture needle 1315 is prevented from contaminating the sample and affecting detection. The integrated needle 1325 needs to be cleaned before aspirating the sample and the reagent and after spitting the sample and the reagent, so that the integrated needle 1325 is prevented from contaminating the sample or the reagent to affect the detection. The reagent needle 1335 needs to be cleaned both before the sample is drawn and after the sample is ejected, so as to prevent the reagent needle 1335 from contaminating the reagent and the sample and affecting the detection. The stirring rod 196 needs to be cleaned before and after stirring, so as to prevent the stirring rod 196 from contaminating the reagent and the sample to affect the detection. The puncture needle cleaning mechanism 201 is arranged between the sample incubation module 14 and the sample conveying module 11, the comprehensive needle cleaning mechanism 202 is arranged adjacent to the puncture needle cleaning mechanism 201, the reagent needle cleaning mechanism 203 is arranged between the reagent storage module 15 and the sample incubation module 14, and the stirring rod cleaning mechanism 204 is arranged between the reagent storage module 15 and the sample incubation module 14.

The reagent needle cleaning mechanism 203 comprises a reagent needle liquid supply assembly, a reagent needle cleaning pool and a reagent needle liquid discharge pipeline. The overall shape of the reagent needle cleaning tank is rectangular, and the reagent needle cleaning tank is disposed between the sample incubation module 14 and the first reagent storage mechanism 151. The reagent needle liquid supply assembly is connected with the reagent needle 1335 and is used for injecting cleaning liquid into the inner cavity of the reagent needle 1335; the reagent needle cleaning tank has a reagent needle cleaning tank for accommodating the reagent needle 1335 therein, and a reagent needle discharging line having a reagent needle suction power unit is connected to a lower portion of the reagent needle cleaning tank. When the reagent needle 1335 is cleaned, the reagent needle 1335 extends into the reagent needle cleaning tank, the reagent needle 1335 liquid supply pipeline introduces cleaning liquid into the reagent needle 1335, and the cleaning liquid enters the reagent needle cleaning tank through the reagent needle 1335, so that the inside and the outside of the reagent needle 1335 can be cleaned; the reagent needle suction power part can provide cleaning power to ensure clean cleaning; after the cleaning is completed, the reagent needle suction power unit sucks the cleaning solution inside the reagent needle cleaning bath and the reagent needle 1335.

Optionally, the reagent needle supply assembly includes a reagent needle cleaning main pipe and two reagent needle cleaning branch pipes, and the reagent needle cleaning main pipe and the two reagent needle cleaning branch pipes are both disposed on the reagent needle mounting assembly 1334. One end of each reagent needle cleaning branch pipe is communicated with the corresponding reagent needle 1335, and the other end of each reagent needle cleaning branch pipe is communicated with the cleaning main pipe. The cleaning liquid enters the corresponding reagent needle cleaning branch pipe through the reagent needle cleaning main pipe, and cleans the corresponding reagent needle 1335, so that the cleanness of the reagent needle 1335 is ensured. Moreover, the two reagent needles 1335 use the reagent needle cleaning main pipe in common to supply the cleaning liquid to the reagent needle cleaning branch pipes, thereby reducing the number of pipes and further reducing the complexity of the structure.

Optionally, the reagent needle cleaning mechanism 203 further comprises a reagent needle control assembly comprising a reagent needle control main valve and two reagent needle control branch valves. The main cleaning pipe is provided with a main reagent needle control valve, and each branch cleaning pipe is provided with a branch reagent needle control valve. When the reagent needle 1335 is cleaned, the reagent needle control main valve and the reagent needle control branch valve corresponding to the reagent needle 1335 are opened, and the other reagent needle control branch valve is closed; when the reagent needle 1335 sucks or discharges a sample, the reagent needle control branch valve corresponding to the reagent needle 1335 is opened, and the reagent needle control main valve and the other reagent needle control branch valve are closed. When the reagent needle 1335 is heated, the reagent needle control main valve and the reagent needle control branch valve corresponding to the reagent needle 1335 are closed.

Similarly, the structure of the integrated needle cleaning mechanism 202 and the stirring rod cleaning mechanism 204 is completely the same as that of the reagent needle cleaning mechanism 203, and the operation principle is also the same. And need not be described in detail herein. In another embodiment of the present invention, the configuration of the puncture needle washing mechanism 201 may be completely the same as that of the reagent needle washing mechanism 203, and the operation principle may be the same.

In this embodiment, the puncture needle cleaning mechanism 201 includes a puncture needle cleaning pool 2011 and a liquid collecting pool, the puncture needle cleaning pool 2011 is disposed on the puncture needle mechanism 131, the liquid collecting pool is disposed below the puncture needle cleaning pool 2011, the puncture needle cleaning pool 2011 is configured to clean the puncture needle 1315 of the puncture needle mechanism 131, and the liquid collecting pool is configured to receive the cleaning liquid leaked from the puncture needle cleaning pool 2011. In addition, the puncture needle cleaning mechanism 201 further includes a first puncture needle liquid supply assembly, a second puncture needle liquid supply assembly, a first puncture needle liquid discharge pipeline, a second puncture needle liquid discharge pipeline, a first puncture needle suction power component, and a second puncture needle suction power component. The puncture needle cleaning pool 2011 is arranged on the puncture needle support frame 1311 through a connecting plate, the puncture needle cleaning pool 2011 is arranged corresponding to the puncture needle 1315, and the liquid collecting pool is arranged between the sample incubation module 14 and the sample conveying module 11.

The first needle fluid supply assembly is in communication with the interior of the needle 1315 for providing a cleaning fluid to the interior of the needle 1315 for cleaning the interior of the needle 1315. The second needle supply assembly is in communication with the needle wash reservoir 2011, the needle 1315 extends into the needle wash reservoir 2011, and the second needle supply assembly provides cleaning fluid to the needle wash reservoir 2011 to clean the exterior of the needle 1315. The first puncture needle suction power component is arranged on the first puncture needle liquid discharge pipeline, and the second puncture needle suction power component is arranged on the second puncture needle liquid discharge pipeline. The first puncture needle drain line communicates with the interior of the puncture needle 1315, and the second puncture needle drain line communicates with the interior of the puncture needle cleaning pool 2011. After the cleaning of the puncture needle 1315 is completed, the cleaning liquid inside the puncture needle 1315 is discharged through the first puncture needle discharge line, and the cleaning liquid in the puncture needle cleaning pool 2011 is discharged through the second puncture needle discharge line. When the puncture needle 1315 is cleaned, the first puncture needle suction power component can be used as power for cleaning the inner wall of the puncture needle 1315, and the second puncture needle suction power component can be used as power for cleaning the outer wall of the puncture needle 1315, so that cleaning is guaranteed; after the cleaning is finished, the first puncture needle suction power component and the second puncture needle suction power component can ensure that the cleaning fluid is completely sucked. The liquid collecting tank is used for preventing the puncture needle cleaning tank 2011 from leaking liquid and has a protective effect. Preferably, the first puncture needle suction power component adopts a diaphragm pump as a power source, and the second puncture needle suction power component adopts a peristaltic pump as a power source.

Referring to fig. 19, since the reagent needle mechanism 133 has a double-ended needle structure, when transferring the reagent, the reagent needle mechanism 133 may interfere with the components such as the second transfer mechanism 162, the stirring module 19, the sample incubation module 14, and the first reagent storage mechanism 151, and the blood analyzer 1 may be stopped, so that a space for avoiding one of the reagent needles 1335 is defined, and when one of the reagent needles 1335 is operated, the other reagent needle 1335 should be located in the space for avoiding the other reagent needle. Moreover, the test platform 101 is provided with a groove at the clearance space, and when the reagent needle 1335 moves downwards under the driving of the reagent needle lifting driving assembly 1332, the reagent needle 1335 can extend into the groove, so that the reagent needle 1335 can be prevented from interfering with the test platform 110 during downward pricking, and the operation reliability of the reagent needle 1335 can be ensured.

Specifically, when one of the reagent needles 1335 sucks a reagent on the first reagent storage mechanism 151, the other reagent needle 1335 is located in a first space that is a first space avoiding space. When one of the reagent needles 1335 sucks a reagent at the second reagent sucking station of the first reagent storage mechanism 151, the other reagent needle 1335 has a space for avoiding a collision at a position a shown in fig. 19, and the second transfer mechanism 162 needs to avoid the reagent needle 1335, and simultaneously, the reagent needle 1335 is prevented from interfering with other parts when being lifted. When one of the reagent needles 1335 adds a reagent to the sample detection module 17, the space where the other reagent needle 1335 is located is the second space. When one of the reagent needles 1335 is used to add a reagent at the third reagent adding station of the paramagnetic particle assay detection mechanism 171, the other reagent needle 1335 has a space avoiding a collision at a position B shown in fig. 19, and interference with other parts when the reagent needle 1335 is lifted up and down is avoided. When one of the reagent needles 1335 adds a reagent to the sample incubation module 14, the space where the other reagent needle 1335 is located is the third avoiding space. When one of the reagent needles 1335 adds a reagent at the first reagent adding station on the sample incubation module 14, the other reagent needle 1335 has a space at a position C shown in fig. 19 to avoid collision and interference with other parts when the reagent needle 1335 is lifted. When one of the reagent needles 1335 is cleaned, the space where the other reagent needle 1335 is located is the fourth space. When one of the reagent needles 1335 is cleaned in the reagent needle cleaning mechanism 203, the other reagent needle 1335 has a space at a position C shown in fig. 19 to avoid collision and interference with other parts when the reagent needle 1335 is lifted.

Referring to fig. 21 to 23, in another embodiment of the present invention, the blood analyzer 1 transfers the sample and the reagent using the integrated needle mechanism 132 and the reagent needle mechanism 133:

the specific configurations and movement manners of the integrated needle mechanism 132 and the reagent needle mechanism 133 of the two-needle structure according to the present embodiment are exactly the same as those of the integrated needle mechanism 132 and the reagent needle mechanism 133 of the three-needle structure according to the above-described embodiment. However, the synthetic needle mechanism 132 in the present embodiment takes on the task of transferring the sample; the integrated needle mechanism 132 in the above-described embodiment may or may not be responsible for transferring the sample. The integrated needle cleaning mechanism 202 for cleaning the integrated needle 1325, the reagent needle cleaning mechanism 203 for cleaning the reagent needle 1335, and the avoiding design of the reagent needle mechanism 133 are completely the same as those in the above-described embodiments, and the detailed structures of the integrated needle mechanism 132 and the reagent needle mechanism 133 will not be described in detail.

In one embodiment and another embodiment of the present invention, the first reagent storage mechanism 151 can automatically rotate a reagent required for sample detection to a reagent sucking station, specifically, when the integrated needle mechanism 132 sucks the reagent, the first reagent driving assembly 1514 of the first reagent storage mechanism 151 drives the reagent tray 1513 to drive the reagent bottles thereon to rotate, so that the corresponding reagent bottles move to the first reagent sucking station, and after the integrated needle 1325 sucks the reagent, the reagent bottles move to the second reagent adding station of the sample incubation module 14 to add the reagent; when the reagent needle 1335 sucks the reagent, the first reagent driving assembly 1514 of the first reagent storage mechanism 151 drives the reagent tray 1513 to drive the reagent bottles thereon to rotate, so that the corresponding reagent bottles move to the second reagent sucking station, and after the reagent needle 1335 sucks the reagent, the reagent bottles move to the first reagent adding station of the sample incubation module 14 to add the reagent.

Referring to fig. 24, in still another embodiment of the present invention, the blood analyzer 1 transfers the sample and the reagent using a dispensing needle mechanism 134:

specifically, the dispensing needle mechanism 134 is used to aspirate a sample such as a test tube without a test tube cap in an open container, or to aspirate a reagent in a reagent bottle. The dispensing needle mechanism 134 includes a dispensing needle support frame, a dispensing needle lifting/lowering drive unit, a dispensing needle rotation drive unit, a dispensing needle attachment unit, and a dispensing needle. The dispensing needle support frame can play a supporting role, is fixedly installed on the test platform 101 and is used for supporting the dispensing needle lifting drive assembly, the dispensing needle rotation drive assembly, the dispensing needle installation assembly and the dispensing needle on the test platform 101. The dispensing needle is used for sucking and discharging a sample and a reagent, and the dispensing needle mounting assembly is used for mounting the dispensing needle and is mounted on the dispensing needle support frame. The dispensing needle lifting driving assembly is connected with the dispensing needle mounting assembly, and can drive the dispensing needle mounting assembly to move up and down, so that the dispensing needle is driven to move to suck and discharge samples or reagents. The dispensing needle rotation driving assembly is also connected with the dispensing needle mounting assembly, and the dispensing needle rotation driving assembly can drive the dispensing needle mounting assembly to rotate, so that the dispensing needle moves to a non-puncture station of the sample conveying module 11 to absorb a sample, moves to a first reagent absorption station of the first reagent storage mechanism 151 to absorb a reagent, moves to a filling station of the sample incubation module 14 to add a sample or a reagent, or moves to a third reagent adding station of the sample detection module 17 to add a reagent. Alternatively, the dispensing needle may have a heating function.

Specifically, the dispensing needle lifting drive assembly comprises a dispensing needle lifting drive motor and a dispensing needle lifting transmission component. The device comprises a dispensing needle lifting driving motor, a dispensing needle lifting transmission component, a dispensing needle mounting component, a dispensing needle lifting driving motor, a dispensing needle lifting driving component and a dispensing needle mounting component, wherein the dispensing needle lifting driving motor is mounted on a dispensing needle supporting frame, the dispensing needle lifting transmission component is mounted on the dispensing needle lifting driving motor and the dispensing needle mounting component, and the dispensing needle lifting transmission component is in transmission connection with an output shaft of the dispensing needle lifting driving motor and the dispensing needle mounting component so as to drive the dispensing needle mounting. The dispensing needle rotation drive unit includes a dispensing needle rotation drive motor and a dispensing needle rotation transmission member. The injection needle rotating drive motor is arranged on the injection needle supporting frame, the injection needle rotating transmission component is arranged on the injection needle rotating drive motor and the injection needle mounting assembly, and the injection needle rotating transmission component is in transmission connection with an output shaft of the injection needle rotating drive motor and the injection needle mounting assembly so as to drive the injection needle mounting assembly to rotate and further drive the injection needle to rotate. The injection needle mounting assembly comprises an injection needle rotating shaft and an injection needle rotating arm, one end of the injection needle rotating shaft is connected with an injection needle rotating transmission component and an injection needle lifting transmission component, the other end of the injection needle rotating shaft extends out along the vertical direction, one end of the injection needle rotating arm is mounted on the extending end of the injection needle rotating shaft, the other end of the injection needle rotating arm extends towards the direction away from the injection needle rotating shaft, and the injection needle is arranged on one end of the injection needle rotating arm away from the injection needle rotating shaft. The dispensing needle lifting transmission member and the dispensing needle rotation transmission member may be a synchronous belt transmission structure, or may be a chain transmission structure or the like for realizing motion transmission.

When the dispensing needle mechanism 134 transfers a sample, the dispensing needle lifting drive assembly drives the dispensing needle rotating shaft to drive the dispensing needle rotating arm to rotate, and then the dispensing needle rotating arm drives the dispensing needle to rotate to the non-puncture station of the sample conveying module 11; the dispensing needle lifting driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to descend, the dispensing needle rotating arm drives a dispensing needle to descend, and the dispensing needle sucks a sample at a non-puncture station; after the sample is sucked, the dispensing needle lifting driving assembly drives the dispensing needle rotating shaft to drive the dispensing needle rotating arm to ascend, and then the dispensing needle rotating arm drives the dispensing needle to ascend; the dispensing needle rotation driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to rotate, and then the dispensing needle rotating arm drives a dispensing needle to rotate to a filling station of the sample incubation module 14; the dispensing needle lifting driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to descend, the dispensing needle rotating arm drives a dispensing needle to descend, and the dispensing needle adds a sample to a reaction cup of the sample incubation module 14 at a filling station; after the sample is added, the dispensing needle lifting driving assembly drives the dispensing needle rotating shaft to drive the dispensing needle rotating arm to ascend, and then the dispensing needle rotating arm drives the dispensing needle to ascend.

When the dispensing needle mechanism 134 transfers a reagent, the dispensing needle lifting drive assembly drives the dispensing needle rotating shaft to drive the dispensing needle rotating arm to rotate, and then the dispensing needle rotating arm drives the dispensing needle to rotate to a reagent sucking station of the first reagent storage mechanism 151; the dispensing needle lifting driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to descend, and then the dispensing needle rotating arm drives a dispensing needle to descend, and the dispensing needle sucks a reagent at a reagent sucking station; after reagent is sucked, the dispensing needle lifting driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to ascend, and then the dispensing needle rotating arm drives a dispensing needle to ascend; the dispensing needle rotation driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to rotate, and then the dispensing needle rotating arm drives a dispensing needle to rotate to a filling station of the sample incubation module 14; the dispensing needle lifting driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to descend, the dispensing needle rotating arm drives a dispensing needle to descend, and the dispensing needle adds a reagent into a reaction cup of the sample incubation module 14 at a filling station; or the dispensing needle rotation driving assembly drives the dispensing needle rotating shaft to drive the dispensing needle rotating arm to rotate, and then the dispensing needle rotating arm drives the dispensing needle to rotate to a third reagent adding station of the sample detection module 17; the dispensing needle lifting driving assembly drives a dispensing needle rotating shaft to drive a dispensing needle rotating arm to descend, the dispensing needle rotating arm drives a dispensing needle to descend, and the dispensing needle adds a reagent into a reaction cup of the sample detection module 17 at a third reagent adding station; after the reagent is added, the dispensing needle lifting driving assembly drives the dispensing needle rotating shaft to drive the dispensing needle rotating arm to ascend, and then the dispensing needle rotating arm drives the dispensing needle to ascend.

The cleaning module 20 further includes a dispensing needle cleaning mechanism for cleaning the dispensing needle. The injection needle needs to be cleaned before sucking the sample and the reagent and after discharging the sample and the reagent, so that the injection needle is prevented from polluting the sample or the reagent to influence detection. The dispensing needle cleaning mechanism is disposed between the sample incubation module 14 and the sample transport module 11. Alternatively, the specific structure of the dispensing needle cleaning mechanism may be completely the same as that of the reagent needle cleaning mechanism 203, and the working principle is also the same; of course, the specific configuration of the dispensing needle washing mechanism may be the same as the specific configuration and operation principle of the puncture needle washing mechanism 201.

Referring to fig. 1, the blood analyzer 1 further includes a liquid path module 21, the liquid path module 21 includes a liquid path control mechanism, a liquid storage mechanism and a waste liquid mechanism, and the liquid path control mechanism, the liquid storage mechanism and the waste liquid mechanism are disposed in the placing cavity 104. The liquid path control mechanism is respectively communicated with the liquid storage mechanism and the waste liquid mechanism, and is also respectively communicated with the puncture needle cleaning mechanism 201, the comprehensive needle cleaning mechanism 202, the reagent needle cleaning mechanism 203 and the stirring rod cleaning mechanism 204. When the puncture needle cleaning mechanism 201 cleans the puncture needle 1315, the liquid storage mechanism conveys the cleaning liquid to the puncture needle 1315 and the first puncture needle cleaning pool 2011 through the first puncture needle liquid supply assembly and the second puncture needle liquid supply assembly, and after cleaning is completed, the cleaning liquid returns to the waste liquid mechanism through the first puncture needle liquid discharge pipeline and the second puncture needle liquid discharge pipeline. When the reagent needle cleaning mechanism 203 cleans the reagent needle 1335, the liquid storage mechanism conveys the cleaning liquid to the reagent needle 1335 and the reagent needle cleaning pool through the reagent needle liquid supply assembly, and after cleaning is finished, the cleaning liquid returns to the waste liquid mechanism through the reagent needle liquid discharge pipeline. The connection relationship between the integrated needle cleaning mechanism 202 and the stirring rod cleaning mechanism 204 and the liquid storage mechanism and the waste liquid mechanism is the same as the connection relationship between the reagent needle cleaning mechanism 203 and the liquid storage mechanism and the waste liquid mechanism.

Optionally, the fluid path control mechanism can quantitatively provide cleaning fluid to the puncture needle cleaning mechanism 201, the integrated needle cleaning mechanism 202, the reagent needle cleaning mechanism 203 and the stirring rod cleaning mechanism 204, and the cleaning fluid provided by the quantitative component can avoid the residual and overflow of the cleaning fluid, so as to ensure the cleaning effect and further ensure the accuracy of the detection result. Preferably, the dosing member may be a syringe, although the dosing member may be other members capable of dosing the cleaning fluid.

Furthermore, the blood analyzer 1 further includes a rocker arm and a display provided on the rocker arm. The rocking arm can drive the display motion for display every single move, horizontal rotation, front and back translation, upper and lower translation have different positions, satisfy different operating personnel's user demand, facilitate the use. Moreover, the display has a touch screen, and the control of the blood analyzer 1 is realized through the touch screen, and meanwhile, the display is also provided with a keyboard and a mouse, so that the operation is convenient.

Referring to fig. 1 to 3 and 21 to 24, another embodiment of the present invention further provides a blood analyzer 1, which includes a sample transport module 11 for transporting a sample to be tested, a dispensing module 13 for aspirating the sample or reagent, a sample incubation module 14 for incubating the sample, a reagent storage module 15 for storing the reagent, a transfer module 16 for transferring a reaction cup, and a sample detection module 17 for detecting the sample. The sample incubation module 14 is arranged in a disc-shaped structure, a plurality of placing positions 14311 for placing reaction cups are arranged on the sample incubation module 14, and the sample incubation module 14 can rotate and drive the reaction cups in the placing positions 14311 to rotate. The reagent storage module 15 comprises a rotatable first reagent storage mechanism 151, the first reagent storage mechanism 151 being capable of storing a plurality of reagents. The sample detection module 17 includes a paramagnetic particle detection mechanism 171 and an optical detection mechanism, the paramagnetic particle detection mechanism 171 performs a paramagnetic particle detection on the sample, and the optical detection mechanism performs an optical detection on the sample. The transfer module 16 and the sample detection module 17 are located at one side of the sample incubation module 14, and the transfer module 16 can transfer the reaction cup to the placing position 14311 of the sample incubation module 14. The dispensing module 13 is located between the sample incubation module 14, the first reagent storage mechanism 151, the sample transport module 11, and the sample detection module 17. The dispensing module 13 can transfer the sample from the sample transport module 11 to the reaction cup of the sample incubation module 14, and the dispensing module 13 can also transfer the reagent from the first reagent storage mechanism 151 to the reaction cup of the sample incubation module 14 or the reaction cup of the sample detection module 17. The transfer module 16 can transfer the cuvettes in the sample incubation module 14 to the magnetic bead detection mechanism 171 or the optical detection mechanism.

In the present embodiment, the sample transport module 11, the cup advancing module 12, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16, and the sample detection module 17 of the blood analyzer 1 are executed in the following order: the transfer module 16 transfers the empty reaction cup conveyed by the cup feeding module 12 to the placing position 14311 of the sample incubation module 14 at the cup taking and placing station, the sample conveying module 11 conveys the sample to be detected, the dispensing module 13 sucks the sample and then rotates to the dispensing station of the sample incubation module 14 to add the sample into the reaction cup of the sample incubation module 14, the dispensing module 13 sucks the reagent at the reagent sucking station of the first reagent storage mechanism 151 and adds the reagent into the reaction cup of the sample incubation module 14, after the reagent is added to the reaction cup of the sample incubation module 14 and is spaced for a period of time, the transfer module 16 transfers the reaction cup to which the sample and the reagent are added to the magnetic bead method detection mechanism 171 or the optical method detection mechanism to perform magnetic bead method detection or optical method detection, and sample parameters are obtained. After the blood analyzer 1 of the present invention performs the above steps, the modular operation can be easily realized, the modules can be conveniently added to the blood analyzer 1 to realize the corresponding functions, the expansion is easy, and meanwhile, the blood analyzer 1 of the present invention can realize better functions, the operation efficiency is improved, and the use is convenient.

Further, the first reagent storage mechanism 151 is provided in a disk-shaped structure. Discoid first reagent storage mechanism 151 can conveniently rotate, and then is convenient for rotate reagent on it and inhale the reagent station, conveniently divide module 13 of annotating to absorb reagent. Furthermore, the first reagent storage mechanism 151 is provided separately from the sample incubation module 14. That is, the first reagent storage mechanism 151 and the sample incubation module 14 are separately provided with a certain distance therebetween. This can increase the storage capacity of the first reagent storage mechanism 151 and the sample incubation block 14, ensuring the operating efficiency of the blood analyzer 1. Moreover, the dispensing module 13 can also transfer the sample and the reagent easily. Of course, in other embodiments of the present invention, the axis of the first reagent storage mechanism 151 coincides with the axis of the sample incubation module 14. At this time, the sample incubation module 14 is disposed in the first reagent storage mechanism 151, that is, the first reagent storage mechanism 151 is sleeved outside the sample incubation module 14, so that the occupied space can be reduced, and the volume of the blood analyzer 1 can be further reduced.

Still further, the blood analyzer 1 further includes a recovery module 18 and a cup feeding module 12 for feeding reaction cups. The recovery module 18 is disposed at the side of the sample detection module 17, the cup entering module 12 is disposed at the side of the sample incubation module 14, and the transfer module 16 can transfer the empty reaction cup conveyed by the cup entering module 12 to the placement position 14311 of the sample incubation module 14; the transfer module 16 can also transfer the reaction cups detected by the sample detection module 17 to the recovery module 18. The recovery module 18 is provided with a cup losing opening, the cup feeding module 12 is provided with an empty cup taking station, the blood analyzer 1 is provided with a cup taking and placing station corresponding to the sample incubation module 14, the sample detection module 17 is provided with a detection station, and at least three collinear settings of the empty cup taking station, the cup losing opening, the cup taking and placing station and the detection station correspond to the movement track of the transfer module 16. For example, the cup-throwing station, the cup-taking-and-emptying station, and the cup-taking-and-emptying station may be arranged in a collinear manner, or the cup-taking-and-emptying station, the sample detection module 17 may be arranged in a collinear manner, or all the collinear manners.

The transfer module 16 thus grips an empty reaction cup at the cup taking and placing station and transfers the empty reaction cup to the cup taking and placing station of the sample incubation module 14; the transfer module 16 can also take out the reaction cup at the cup taking and placing station, transfer the reaction cup to the sample detection module 17 for detection, and transfer the reaction cup on the sample detection module 17 to the cup losing opening by the detection module after detection is completed. Get empty cup station, lose the rim of a cup, get and put cup station, detect in the station at least three collineation setting and can make transfer module 16 toward doing linear reciprocating motion in same direction, save the space that transfer module 16 took, and then reduce blood analyzer 1's whole quick-witted size, transfer module 16 and do linear motion simultaneously and can also avoid transfer module 16 or other spare parts to take place to interfere, guarantee the reliability of motion.

The structures of the respective parts of the blood analyzer 1 of the present embodiment, such as the sample transport module 11, the cup entering module 12, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16, the stirring module 19, and the sample detection module 17, are completely the same as the structures and the operation principles of the sample transport module 11, the cup entering module 12, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16, and the sample detection module 17 of the blood analyzer 1 of the above-described embodiment of the present invention, the structures and operation principles of the sample transportation module 11, the cup entering module 12, the dispensing module 13, the sample incubation module 14, the reagent storage module 15, the transfer module 16 and the sample detection module 17 in the above embodiments of the present invention have been described in detail in the above embodiments, and are not described herein again.

Referring to fig. 1 to 3 and 21 to 24, the present invention further provides a blood analyzer 1, which includes a cup feeding module 12 for transporting reaction cups, a sample transporting module 11 for transporting a sample to be measured, a dispensing module 13 for aspirating and discharging a sample or a reagent, a sample incubating module 14 for incubating a sample, a transferring module 16 for transferring reaction cups, a reagent storing module 15 for storing a reagent, a sample detecting module 17 for detecting a sample, and a recovering module 18. The sample incubation module 14 is arranged in a disc-shaped structure, a plurality of placing positions 14311 for placing reaction cups are arranged on the sample incubation module 14, and the sample incubation module 14 can rotate and drive the reaction cups in the placing positions 14311 to rotate. The reagent storage module 15 comprises a rotatable first reagent storage mechanism 151, the first reagent storage mechanism 151 being capable of storing a plurality of reagents. The cup feeding module 12, the transferring module 16 and the sample detecting module 17 are located at one side of the sample incubation module 14, the recycling module 18 is located at the side of the sample detecting module 17, and the transferring module 16 can transfer the reaction cup to the placing position 14311 of the sample incubation module 14. The dispensing module 13 is located among the sample incubation module 14, the first reagent storage mechanism 151, the sample transport module 11, and the sample detection module 17, the dispensing module 13 can transfer the sample from the sample transport module 11 to the reaction cup of the sample incubation module 14, and the dispensing module 13 can also transfer the reagent from the first reagent storage mechanism 151 to the reaction cup of the sample incubation module 14 or the reaction cup of the sample detection module 17. The transfer module 16 can transfer the reaction cups in the sample incubation module 14 to the sample detection module 17; the transfer module 16 can also transfer the reaction cups detected by the sample detection module 17 to the recovery module 18.

The recovery module 18 is provided with a cup losing opening, the cup feeding module 12 is provided with an empty cup taking station, the blood analyzer 1 is provided with a cup taking and placing station corresponding to the sample incubation module 14, the sample detection module 17 is provided with a detection station, and at least three collinear settings of the empty cup taking station, the cup losing opening, the cup taking and placing station and the detection station correspond to the movement track of the transfer module 16. For example, the cup-throwing station, the cup-taking-and-emptying station, and the cup-taking-and-emptying station may be arranged in a collinear manner, or the cup-taking-and-emptying station, the sample detection module 17 may be arranged in a collinear manner, or all the collinear manners.

Further, the first reagent storage mechanism 151 is provided in a disk-shaped structure. Discoid first reagent storage mechanism 151 can conveniently rotate, and then is convenient for rotate reagent on it and inhale the reagent station, conveniently divide module 13 of annotating to absorb reagent. Furthermore, the first reagent storage mechanism 151 is provided separately from the sample incubation module 14. That is, first reagent storage mechanism 151 is disposed apart from sample incubation module 14 with a distance therebetween. This can increase the storage capacity of the first reagent storage mechanism 151 and the sample incubation block 14, ensuring the operating efficiency of the blood analyzer 1. Moreover, the dispensing module 13 can also transfer the sample and the reagent easily.

Still further, the sample detection module 17 includes a paramagnetic particle detection unit 171 and an optical detection unit, the paramagnetic particle detection unit 171 performs a paramagnetic particle detection on the sample, and the optical detection unit performs an optical detection on the sample. The magnetic bead detection unit 171 can perform magnetic bead detection on the sample, and the optical detection unit can perform optical detection on the sample. When the sample needs to be detected correspondingly, the transfer module 16 can transfer the cuvette, to which the sample and the reagent are added, on the sample incubation module 14 to the optical detection mechanism or the magnetic bead detection mechanism 171.

Referring to fig. 1 to 3 and 21 to 24, the present invention further provides a control method of a blood analyzer 1, in which the blood analyzer 1 includes a sample transportation module 11 for transporting a sample to be tested, a dispensing module 13 for aspirating and discharging the sample or reagent, a sample incubation module 14 for incubating the sample, a transfer module 16 for transferring a reaction cup, and a sample detection module 17 for detecting the sample;

the sample incubation module 14 is arranged in a disc-shaped structure, the sample incubation module 14 is provided with a plurality of placing positions 14311 for placing reaction cups, and the sample incubation module 14 can rotate and drive the reaction cups in the placing positions 14311 to rotate;

the sample detection module 17 comprises a magnetic bead method detection mechanism 171 and an optical method detection mechanism, the magnetic bead method detection mechanism 171 performs magnetic bead method detection on the sample, and the optical method detection mechanism performs optical method detection on the sample;

the control method of the blood analyzer 1 includes the steps of:

acquiring detection information of a sample test item;

transfer module 16 is capable of placing an empty reaction cup into place 14311 of sample incubation module 14;

the dispensing module 13 sucks a sample at the sample conveying module 11 or a reagent at the reagent storage module 15, and adds the sample or the reagent into a reaction cup of the sample incubation module 14;

the transfer module 16 can transfer the cuvette to which the sample and the reagent are added to the magnetic bead method detection unit 171 or the optical method detection unit.

When the blood analyzer 1 of the present invention detects a sample, after the main control module 22 of the blood analyzer 1 first obtains the detection information of a sample test item, the main control module 22 controls the transfer module 16 to transfer an empty reaction cup to the placement position 14311 of the sample incubation module 14, and the main control module 22 then controls the dispensing module 13 to transfer a corresponding sample and various reagents required by the sample to perform the item detection to the corresponding reaction cup on the sample incubation module 14; subsequently, the main control module 22 controls the transfer module 16 to transfer the cuvette to which the sample and the reagent are added to the paramagnetic particle method detection mechanism 171 or the optical method detection mechanism according to the item detection information of the sample, that is, when the sample is detected by the paramagnetic particle method, the main control module 22 controls the transfer module 16 to transfer the cuvette to which the sample and the reagent are added to the paramagnetic particle method detection mechanism 171 according to the control instruction; when the sample is detected optically, the main control module 22 controls the transfer module 16 to transfer the cuvette to which the sample and the reagent are added to the optical detection mechanism according to the control instruction.

Further, the detection information is obtained by scanning the detection code on the container containing the sample. At this time, the detection code on the container can be scanned by the scanning mechanism 113 of the main control module 22, and the item detection information of the sample can be obtained according to the detection code, so that the main controller can conveniently send out a control instruction. Of course, in other embodiments of the present invention, the detection information is information of a detection instruction of the manually input sample. The item detection information of the sample is input in a manual input mode, and then the main controller controls the separate injection module 13, the sample incubation module 14, the first reagent storage mechanism 151, the sample detection module 17 and the transfer module 16 to move respectively, so that the sample and the corresponding reagent are transferred into the reaction cup, and the sample can be subjected to corresponding item detection.

Further, when the detection information is detection information by a paramagnetic particle method, the transfer module 16 transfers the cuvette to the detection mechanism 171 by a paramagnetic particle method for detection. When the detection information of the sample is the detection information of the magnetic bead method, the main control module 22 controls the movement of the transfer module 16, and transfers the reaction cup to the magnetic bead method detection mechanism 171 for the magnetic bead method detection. When the detection information is optical detection information, the transfer module 16 transfers the cuvette to an optical detection mechanism for optical detection. When the detection information of the sample is the optical detection information, the main control module 22 controls the movement of the transfer module 16, and transfers the reaction cup to the optical detection mechanism for optical detection.

Still further, when the optical detection information is immunoturbidimetric detection information, the transferring module 16 transfers the cuvette to an immunoturbidimetric detection position of the optical detection mechanism for optical detection. When the optical detection information of the sample is the immunoturbidimetric detection information, the main control module 22 controls the movement of the transfer module 16, and transfers the cuvette to the immunoturbidimetric detection position of the optical detection mechanism for optical detection.

When the optical detection information is the chromogenic substrate method detection information, the transfer module 16 transfers the reaction cup to a chromogenic substrate method detection position on the optical detection mechanism for optical detection. When the optical detection information of the sample is the detection information of the chromogenic substrate method, the main control module 22 controls the transfer module 16 to move, and transfers the reaction cup to the detection position of the chromogenic substrate method on the optical detection mechanism for optical detection. The blood analyzer 1 of the present invention performs different item tests on the sample by performing the magnetic bead test and the optical test on the sample, and performing the immunoturbidimetric test and the chromogenic substrate test by the optical test, so as to obtain different sample parameters.

Referring to fig. 1 to 3, in one embodiment of the present invention, the dispensing module 13 includes a puncture needle mechanism 131, an integrated needle mechanism 132, and a reagent needle mechanism 133. The blood analyzer 1 has a three-pin structure, and the puncture needle mechanism 131 adds a sample to a reaction cup of the sample incubation block 14. The reagent needle mechanism 133 adds reagents to the reaction cup of the sample incubation module 14. The integrated needle mechanism 132 adds a sample or reagent to the reaction cup of the sample incubation module 14.

Referring to fig. 21 to 23, in another embodiment of the present invention, the dispensing module 13 includes an integrated needle mechanism 132 and a reagent needle mechanism 133. The blood analyzer 1 has a two-needle structure. The integrated needle mechanism 132 is capable of adding a sample or reagent to the reaction cup of the sample incubation module 14; the reagent needle mechanism 133 is capable of adding reagents into the reaction cup of the sample incubation module 14.

Referring to fig. 24, in yet another embodiment of the present invention, the dispensing module 13 includes a dispensing needle mechanism 134. The blood analyzer 1 is a needle structure. The dispensing needle mechanism 134 is capable of adding a sample or reagent to the reaction cup of the sample incubation module 14.

The specific configurations and operation principles of the puncture needle mechanism 131, the integrated needle mechanism 132, the reagent needle mechanism 133, and the dispensing needle mechanism 134 of the blood analyzer 1 have been described in detail above, and will not be described again here.

The technical features of the embodiments described above can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

A blood analyzer is characterized by comprising a sample conveying module for conveying a sample to be detected, a dispensing module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a reagent storage module for storing the reagent, a transfer module for transferring a reaction cup and a sample detection module for detecting the sample;

the sample incubation module is arranged in a disc-shaped structure, a plurality of placing positions for placing reaction cups are arranged on the sample incubation module, and the sample incubation module can rotate and drive the reaction cups in the placing positions to rotate;

the reagent storage module comprises a rotatable first reagent storage mechanism which is arranged in a disc-shaped structure, and the first reagent storage mechanism can store a plurality of reagents; the first reagent storage mechanism is arranged separately from the sample incubation module;

the transfer module is capable of transferring the reaction cup into the placement position of the sample incubation module;

the dispensing module is capable of transferring a sample from the sample transport module into the reaction cup of the sample incubation module, the dispensing module is further capable of transferring a reagent from the first reagent storage mechanism into the reaction cup of the sample incubation module or the reaction cup of the sample detection module;

the transfer module is capable of transferring the reaction cups in the sample incubation module to the sample detection module.
A blood analyzer is characterized by comprising a sample conveying module for conveying a sample to be detected, a dispensing module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a reagent storage module for storing the reagent, a transfer module for transferring a reaction cup and a sample detection module for detecting the sample;

the sample incubation module is arranged in a disc-shaped structure, a plurality of placing positions for placing reaction cups are arranged on the sample incubation module, and the sample incubation module can rotate and drive the reaction cups in the placing positions to rotate;

the reagent storage module comprises a rotatable first reagent storage mechanism capable of storing a plurality of reagents;

the sample detection module comprises a magnetic bead method detection mechanism and an optical method detection mechanism, the magnetic bead method detection mechanism carries out magnetic bead method detection on the sample, and the optical method detection mechanism carries out optical method detection on the sample;

the transfer module is capable of transferring the reaction cup into the placement position of the sample incubation module;

the dispensing module is capable of transferring a sample from the sample transport module into the reaction cup of the sample incubation module, the dispensing module is further capable of transferring a reagent from the first reagent storage mechanism into the reaction cup of the sample incubation module or the reaction cup of the sample detection module;

the transfer module can transfer the reaction cup in the sample incubation module to the magnetic bead method detection mechanism or the optical method detection mechanism.
The blood analyzer of claim 2, wherein the first reagent storage mechanism is disposed in a disk-like configuration;

the first reagent storage mechanism is disposed separately from the sample incubation module.
The blood analyzer of claim 2, wherein the first reagent storage mechanism is disposed in a disk-like configuration;

the axis of the first reagent storage mechanism coincides with the axis of the sample incubation module.
The blood analyzer of claim 2, further comprising a recovery module and a cup feeding module for conveying the reaction cups, wherein the recovery module has a cup losing opening, the cup feeding module has a cup taking and emptying station, the blood analyzer has a cup taking and placing station corresponding to the sample incubation module, the sample detection module has a detection station, and at least three of the cup taking and emptying station, the cup losing opening, the cup taking and placing station and the detection station are arranged in a line and correspond to the motion track of the transfer module.
A blood analyzer is characterized by comprising a cup feeding module for conveying a reaction cup, a sample conveying module for conveying a sample to be detected, a separate injection module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a transfer module for transferring the reaction cup, a reagent storage module for storing the reagent, a sample detection module for detecting the sample and a recovery module;

the sample incubation module is arranged in a disc-shaped structure, a plurality of placing positions for placing reaction cups are arranged on the sample incubation module, and the sample incubation module can rotate and drive the reaction cups in the placing positions to rotate;

the reagent storage module comprises a rotatable first reagent storage mechanism capable of storing a plurality of reagents;

the transfer module is capable of transferring the reaction cup into the placement position of the sample incubation module, the dispensing module is capable of transferring a sample from the sample transport module into the reaction cup of the sample incubation module, the dispensing module is further capable of transferring a reagent from the first reagent storage mechanism into the reaction cup of the sample incubation module or the reaction cup of the sample detection module;

the transfer module is capable of transferring the reaction cups in the sample incubation module to the sample detection module; the transfer module can also transfer the reaction cup which is detected by the sample detection module to the recovery module;

the recovery module is provided with a cup losing opening, the cup feeding module is provided with an empty cup taking station, the blood analyzer is provided with a cup taking and placing station corresponding to the sample incubation module, the sample detection module is provided with a detection station, and the cup losing opening, the cup taking and placing station and at least three collinear settings in the detection station correspond to the movement track of the transfer module.
The blood analyzer of claim 6, wherein the first reagent storage mechanism is disposed in a disk-like configuration;

the first reagent storage mechanism is disposed separately from the sample incubation module.
The blood analyzer of claim 6, wherein the sample detection module comprises a paramagnetic particle detection mechanism for magnetically detecting the sample and an optical detection mechanism for optically detecting the sample;

the transfer module can transfer the reaction cup on the sample incubation module after adding the sample and the reagent to the optical detection mechanism or the magnetic bead detection mechanism.
The hematology analyzer of claim 1, 2 or 6, further comprising a cup feeding module for transporting the reaction cups;

the transfer module comprises a first transfer mechanism and a second transfer mechanism;

the first transfer mechanism is used for conveying the reaction cups conveyed by the cup feeding module to the sample incubation module;

the second transfer mechanism is used for transferring the reaction cup on the sample incubation module after the sample and the reagent are added to the detection module.
The blood analyzer of claim 1, wherein the sample detection module comprises a paramagnetic particle detection mechanism for magnetically detecting the sample and an optical detection mechanism for optically detecting the sample;

the transfer module can transfer the reaction cup on the sample incubation module after adding the sample and the reagent to the optical detection mechanism or the magnetic bead detection mechanism.
The hematology analyzer of claim 10, wherein the transfer module includes a first transfer mechanism and a second transfer mechanism;

the number of the optical detection mechanisms is two, the optical detection mechanisms are respectively a first optical detection mechanism and a second optical detection mechanism, and the magnetic bead method detection mechanism, the second optical detection mechanism and the first optical detection mechanism are sequentially arranged.
The blood analyzer of claim 11, wherein the first transfer mechanism is configured to transfer the cuvettes transferred by the cuvette entry module to the sample incubation module and to transfer the cuvettes on the sample incubation module after adding the sample and the reagent to the first optical detection mechanism;

the second transfer mechanism is used for transferring the reaction cup on the sample incubation module after the sample and the reagent are added to the second optical detection mechanism or the magnetic bead detection mechanism.
The blood analyzer of claim 2, 8 or 10, further comprising a main control module electrically connected to the transfer module, wherein the main control module controls the transfer module to transfer the reaction cup on the sample incubation module to the magnetic bead assay detection mechanism or the optical assay detection mechanism according to a command.
The blood analyzer of claim 2, 8 or 10, wherein the number of the optical detection means is two, and the optical detection means is a first optical detection means and a second optical detection means;

the blood analyzer further comprises a main control module, the main control module is electrically connected with the transfer module, and the main control module controls the transfer module to transfer the reaction cup on the sample incubation module to the first optical detection mechanism or the second optical detection mechanism according to instructions.
The blood analyzer of claim 2, 8 or 10, further comprising a main control module, wherein the main control module comprises a main controller and a scanning mechanism, the main controller is electrically connected with the scanning mechanism, and the scanning mechanism is used for scanning the detection code on the container filled with the sample and conveyed by the sample conveying module and acquiring the detection information of the sample test item in the container;

the main controller is also electrically connected with the separate injection module, the sample incubation module, the first reagent storage mechanism, the sample detection module and the transfer module;

the scanning mechanism can transmit acquired detection information of a sample test item to the main controller, the main controller controls the separate injection module to transfer a corresponding reagent in the first reagent storage mechanism to the reaction cup of the sample incubation module according to the detection information, and the main controller controls the transfer module to move according to the detection information, so that the transfer mechanism transfers the reaction cup added with the sample and the reagent in the sample incubation module to the sample detection module.
The blood analyzer of claim 15, wherein when the detection information is magnetic bead method detection information, the main control module controls the movement of the transfer module and transfers the reaction cup to the magnetic bead method detection mechanism for magnetic bead method detection;

when the detection information is optical detection information, the main control module controls the movement of the transfer module and transfers the reaction cup to the optical detection mechanism for optical detection.
The blood analyzer of claim 16, wherein the optical detection mechanism comprises an immunoturbidimetric detection site and a chromogenic substrate detection site;

when the optical detection information is immunoturbidimetric detection information, the main control module controls the movement of the transfer module and transfers the reaction cup to the immunoturbidimetric detection position on the optical detection mechanism for optical detection;

when the optical detection information is the chromogenic substrate method detection information, the main control module controls the transfer module to move, and transfers the reaction cup to the chromogenic substrate method detection position on the optical detection mechanism for optical detection.
The blood analyzer of claim 1 or 2, further comprising a recovery module comprising a first recovery mechanism disposed on a side of the first optical detection mechanism and a second recovery mechanism disposed on a side of the second optical detection mechanism;

the first transfer mechanism can also discard the reaction cups detected by the first optical detection mechanism to the first recovery mechanism, and the second transfer mechanism can also discard the reaction cups detected by the second optical detection mechanism and the magnetic bead detection mechanism to the second recovery mechanism.
The blood analyzer of claim 18, wherein the first recovery mechanism has a first cup discarding opening, and at least three of the first cup discarding opening, the cup removing opening, the cup placing and taking opening, and the first optical detection mechanism are arranged in a collinear manner and correspond to a motion trajectory of the first transfer mechanism.
The blood analyzer of claim 1, 2 or 6, wherein the dispensing module comprises a dispensing needle mechanism;

the dispensing needle mechanism is capable of transferring a sample from the sample transport module into the reaction cup of the sample incubation module, the dispensing module is further capable of transferring a reagent from the first reagent storage mechanism into the reaction cup of the sample incubation module or the reaction cup of the sample detection module.
The hematology analyzer of claim 20, wherein the hematology analyzer is provided with a pick-and-place cup station, a dispensing station, and a pick-and-place cup station surrounding the sample incubation module; the blood analyzer has a reagent dispensing/aspirating station in the first reagent storage mechanism, and has a reagent dispensing/adding station in the sample detection module.
The blood analyzer according to claim 1, 2 or 6, wherein the dispensing module comprises an integrated needle mechanism for aspirating and discharging a sample or a reagent, and a reagent needle mechanism for aspirating and discharging a reagent;

the integrated needle mechanism is positioned among the sample incubation module, the reagent storage module and the sample delivery module, the integrated needle mechanism can transfer the sample in the sample delivery module into the reaction cup of the sample incubation module, and the integrated needle mechanism can also transfer the reagent in the first reagent storage mechanism into the reaction cup on the sample incubation module;

the reagent needle mechanism is located between the sample incubation module, the reagent storage module and the sample detection module, and the reagent needle mechanism can transfer the reagent in the first reagent storage mechanism into the reaction cup of the sample incubation module or into the reaction cup of the sample detection module.
The hematology analyzer of claim 22, wherein the hematology analyzer is provided with a pick-and-place cup station, a sample application station, a first reagent application station, and a cup pick-and-place cup station surrounding the sample incubation module; the blood analyzer has a first reagent sucking station and a second reagent sucking station on the first reagent storage mechanism, and the blood analyzer has a third reagent adding station on the sample detection module.
The blood analyzer according to claim 1, 2 or 6, wherein the dispensing module comprises a puncture needle mechanism for aspirating and discharging a sample, an integrated needle mechanism for aspirating and discharging a sample or a reagent, and a reagent needle mechanism for aspirating and discharging a reagent;

the puncture needle mechanism is positioned between the sample conveying module and the sample incubation module, and can transfer the sample conveyed by the sample conveying module into the reaction cup of the sample incubation module;

the integrated needle mechanism is located between the sample incubation module, the reagent storage module and the sample transport module, the integrated needle mechanism is capable of transferring the reagent in the first reagent storage mechanism into the reaction cup on the sample incubation module, or the integrated needle mechanism is capable of transferring the sample in the sample transport module into the reaction cup of the sample incubation module;

the reagent needle mechanism is located between the sample incubation module, the reagent storage module and the sample detection module, and the reagent needle mechanism can transfer the reagent in the first reagent storage mechanism into the reaction cup of the sample incubation module or into the reaction cup of the sample detection module.
The blood analyzer of claim 24, wherein the blood analyzer is provided with a pick-and-place cup station, a sample loading station, a first reagent loading station, a second reagent loading station, and a cup pick-up station surrounding the sample incubation module, the blood analyzer having a first reagent aspiration station and a second reagent aspiration station at the first reagent storage mechanism, the blood analyzer having a third reagent loading station at the sample detection module.
The blood analyzer of claim 22 or 24, wherein the reagent needle mechanism comprises a reagent needle driving assembly, a reagent needle mounting assembly and two reagent needles, at least one of the reagent needles has a heating function, the reagent needle driving assembly is in transmission connection with the reagent needle mounting assembly, and the two reagent needles are arranged on the reagent needle driving assembly;

the reagent needle driving assembly drives the reagent needle transmission assembly to move, so that the two reagent needles can move to the first reagent storage mechanism to suck a reagent, move to the sample incubation module to add the reagent, or move to the sample detection module to add the reagent.
The blood analyzer of claim 26, wherein when one of the reagent needles aspirates a reagent on the first reagent storage mechanism, the other reagent needle is located in a first space avoiding position;

when one reagent needle adds a reagent on the sample detection module, the space where the other reagent needle is located is a second avoiding space;

when one reagent needle adds a reagent on the sample incubation module, the space where the other reagent needle is located is a third avoiding space;

when one reagent needle is cleaned, the space where the other reagent needle is located is a fourth avoiding space.
The blood analyzer of claim 24, further comprising a cleaning module including a needle cleaning mechanism for cleaning a needle of the needle mechanism;

the cleaning mechanism comprises a puncture needle cleaning pool and a liquid collecting pool, the puncture needle cleaning pool is arranged on the puncture needle mechanism, the liquid collecting pool is arranged below the puncture needle cleaning pool, the puncture needle cleaning pool is used for cleaning the puncture needle of the puncture needle mechanism, and the liquid collecting pool is used for collecting cleaning liquid leaked from the puncture needle cleaning pool.
The hematology analyzer of claim 1, 2 or 6, further comprising a cup entry module;

the cup feeding module comprises a reaction cup storage mechanism, a reaction cup conveying mechanism and a reaction cup transferring mechanism, the reaction cup conveying mechanism is obliquely arranged, the reaction cup storage mechanism is arranged at the lower position of the reaction cup conveying mechanism, and the reaction cup transferring mechanism is movably arranged on the reaction cup conveying mechanism;

the reaction cup conveying mechanism conveys the reaction cup transfer mechanism to the lower position of the reaction cup conveying mechanism, the reaction cup storage mechanism conveys the reaction cups to the reaction cup transfer mechanism, the reaction cup conveying mechanism conveys the reaction cup transfer mechanism to the higher position of the reaction cup conveying mechanism, an empty cup taking station is arranged on the reaction cup transfer mechanism, and the transfer module grabs the reaction cups on the empty cup taking station.
The hematology analyzer of claim 1, 2 or 6, wherein the reagent storage module further comprises a second reagent storage mechanism for storing a reagent, the second reagent storage mechanism being disposed between the first reagent storage mechanism and the sample transport module;

the integrated needle mechanism is capable of aspirating reagents in the second reagent storage mechanism for addition to the sample incubation module.
The hematology analyzer of claim 30, wherein the second reagent storage mechanism is further capable of storing an emergency sample, preferably wherein the second reagent storage mechanism is movable to the dispensing module;

the dispensing module can suck the emergency treatment sample in the second reagent storage mechanism and add the emergency treatment sample into the reaction cup of the sample incubation module.
The hematology analyzer of claim 1, 2 or 6, further comprising an agitation module disposed proximate to the sample incubation module, the agitation module capable of performing a two-dimensional motion in a vertical plane;

the blood analyzer is also provided with a stirring station, and the stirring module is used for stirring the reaction cup after the sample and the reagent are added into the sample incubation module at the stirring station.
The blood analyzer of claim 1, 2 or 6, wherein the sample transport module comprises an autosampler mechanism for automatically transporting a plurality of containers containing samples arranged in rows on a sample rack;

the automatic sample feeding mechanism is provided with a puncture station and a non-puncture station, the non-puncture station and the puncture station are sequentially arranged, and the separate injection module can be used for respectively filling samples in containers at the puncture station and the non-puncture station;

the distance between the non-piercing station and the piercing station is at least one time the spacing between two adjacent containers.
The blood analyzer of claim 1, 2 or 6, further comprising a testing box having a placement chamber and a testing platform covering the placement chamber, wherein the sample transfer module, the dispensing module, the sample incubation module, the reagent storage module, the transfer module and the detection module are all located on the testing platform;

the blood analyzer also comprises a main control module and a power supply module, wherein the power supply module is electrically connected with the main control module, the main control module is respectively electrically connected with the sample conveying module, the separate injection module, the sample incubation module, the reagent storage module, the transfer module and the detection module, and the main control module and the power supply module are positioned in the placing cavity;

the blood analyzer further comprises a liquid path module, the liquid path module comprises a liquid path control mechanism, a liquid storage mechanism and a waste liquid mechanism, and the liquid path control mechanism, the liquid storage mechanism and the waste liquid mechanism are arranged in the placing cavity.
The control method of the blood analyzer is characterized in that the blood analyzer comprises a sample conveying module for conveying a sample to be detected, a separate injection module for sucking and discharging the sample or a reagent, a sample incubation module for incubating the sample, a transfer module for transferring the reaction cup and a sample detection module for detecting the sample;

the sample incubation module is arranged in a disc-shaped structure, a plurality of placing positions for placing reaction cups are arranged on the sample incubation module, and the sample incubation module can rotate and drive the reaction cups in the placing positions to rotate;

the sample detection module comprises a magnetic bead method detection mechanism and an optical method detection mechanism, the magnetic bead method detection mechanism carries out magnetic bead method detection on the sample, and the optical method detection mechanism carries out optical method detection on the sample;

the control method of the blood analyzer comprises the following steps:

acquiring detection information of a sample test item;

the transfer module is capable of placing the empty reaction cup into the placement position of the sample incubation module;

the dispensing module sucks a sample at the sample conveying module or a reagent at the reagent storage module and adds the sample or the reagent to the reaction cup of the sample incubation module;

the transfer module can transfer the reaction cup added with the sample and the reagent to the magnetic bead method detection mechanism or the optical method detection mechanism.
The control method of a blood analyzer according to claim 34 or 35, wherein the detection information is obtained by scanning a detection code on a container containing a sample;

or, the detection information is information of a detection instruction of a manually input sample.
The control method for a blood analyzer according to claim 36, wherein when the detection information is detection information by a magnetic bead method, the transfer module transfers the cuvette to the detection mechanism by a magnetic bead method for detection;

and when the detection information is optical detection information, the transfer module transfers the reaction cup to the optical detection mechanism for optical detection.
The blood analyzer of claim 36, wherein the optical detection mechanism comprises an immunoturbidimetric detection site and a chromogenic substrate detection site;

when the detection information is optical detection information, the transfer module transfers the reaction cup to the optical detection mechanism for optical detection;

when the optical detection information is immunoturbidimetric detection information, the transfer module transfers the reaction cup to the immunoturbidimetric detection position on the optical detection mechanism for optical detection;

when the optical detection information is the detection information of the chromogenic substrate method, the transfer module transfers the reaction cup to the detection position of the chromogenic substrate method on the optical detection mechanism for optical detection.
The control method for a blood analyzer according to claim 35, wherein the dispensing module includes a dispensing needle mechanism;

the dispensing needle mechanism is capable of adding a sample or reagent into the reaction cup of the sample incubation module.
The control method for a blood analyzer according to claim 35, wherein the dispensing module includes an integrated needle mechanism and a reagent needle mechanism;

the integrated needle mechanism is capable of adding a sample or reagent into the reaction cup of the sample incubation module;

the reagent needle mechanism is capable of adding a reagent to the reaction cup of the sample incubation module.
The control method for a blood analyzer according to claim 35, wherein the dispensing module includes a puncture needle mechanism, an integrated needle mechanism, and a reagent needle mechanism;

the puncture needle mechanism adds a sample into the reaction cup of the sample incubation module;

the reagent needle mechanism adding a reagent into the reaction cup of the sample incubation module;

the integrated needle mechanism adds a sample or reagent to the reaction cup of the sample incubation module.