CN205656203U - A sampling device for immune quantitative analysis appearance - Google Patents

A sampling device for immune quantitative analysis appearance Download PDF

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Publication number
CN205656203U
CN205656203U CN201620083175.8U CN201620083175U CN205656203U CN 205656203 U CN205656203 U CN 205656203U CN 201620083175 U CN201620083175 U CN 201620083175U CN 205656203 U CN205656203 U CN 205656203U
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China
Prior art keywords
sample
sampling
pushing block
guide rail
unloading
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CN201620083175.8U
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Chinese (zh)
Inventor
王斌
姚福立
唐灿
罗宏
王继华
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Guangzhou Wondfo Biotech Co Ltd
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Guangzhou Wondfo Biotech Co Ltd
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Abstract

The utility model relates to a sampling device for immune quantitative analysis appearance belongs to and detects technical field. This sampling device including the sample holder that is used for placing the sample pipe, advance a kind platform, advance a kind transport mechanism, sample holder arranges in on advancing kind platform, and can the effect of advancing kind transport mechanism is down with the sample pipe by waiting that it transports to the sample position to examine the position. When this sampling device was used for immune quantitative analysis appearance, can be nimble manage the sample by waiting that it transports to the sample position to examine the position realized autoinjection's purpose.

Description

Sampling device for immune quantitative analyser
Technical field
This utility model relates to detection technique field, particularly relates to a kind of sampling device for immune quantitative analyser.
Background technology
The major function of fluorescence immunoassay quantitative analysis instrument is: the content of the multiple projects such as various albumen in Quantitative in vitro detection human serum, blood plasma, whole blood or urine, antigen, for the diagnosis of clinical disease, prevent, treat and health monitoring provides data foundation really and accurately.
For meeting current medical industry POCT (the Point-of-care testing to inspection, real-time test) requirement, realize quickly obtaining the purpose of accurate assay, remove numerous and diverse operation sequence, reduce error or the mistake impact on result that manual operation brings, improving test speed, full-automatic fluorescence immunoassay quantitative analysis instrument is an inexorable trend of current Instrument Development.
But, the most existing fluorescence immunoassay detection by quantitative instrument, great majority broadly fall into semi-automated instrument or manual detecting instrument.
Summary of the invention
Based on this, it is necessary for the problems referred to above, a kind of sampling device for immune quantitative analyser is provided, this device promotes sample rack X-axis in the horizontal direction and Y-axis motion respectively, namely it is respectively longitudinal action and crosswise movement, such that it is able to be transported to each sample tube on sample rack sample position, it is achieved the purpose of auto injection.
A kind of sampling device for immune quantitative analyser, including for placing the sample rack of sample tube, sample introduction platform, sample introduction connecting gear and system control module, described sample rack is placed on described sample introduction platform, and can be transported to sample position by position to be checked by sample tube under the effect of described sample introduction connecting gear;
Described sample introduction connecting gear includes the first connecting gear and the second connecting gear;
Described first connecting gear includes the first driving motor, the first transmission band, the first pushing block and the first guide rail, and described first drives motor to drive described first pushing block to move along described first guide rail by described first transmission band;
Described second connecting gear includes the second driving motor, the second transmission band, the second pushing block and the second guide rail, and described second drives motor to drive described second pushing block to move along described second guide rail by described second transmission band;
Described first drives motor and described second to drive motor all to electrically connect with described system control module;
Described first guide rail is arranged in mutually perpendicular directions with described second guide rail, and described first guide rail is arranged the most in the horizontal direction with described second guide rail, described sample rack can move to described second pushing block from displacement to be checked under the promotion of described first pushing block, then moves to sampling position under the promotion of the second pushing block.
In above-mentioned sampling device, the guide rail of the first connecting gear and the second connecting gear is mutually perpendicular to, i.e. first connecting gear and the second connecting gear promote sample rack X-axis in the horizontal direction and Y-axis motion respectively, namely be respectively longitudinal action and crosswise movement, such that it is able to it is transported to each sample tube on sample rack sample position.
Wherein in an embodiment, described first connecting gear also includes cross bar and main spring, described cross bar is installed on described first transmission band, described first pushing block has two pieces, corresponding with described sample rack two ends respectively, and two pieces of described first pushing blocks are rotating is installed on described cross bar two ends, and described main spring two ends are individually fixed on described cross bar and described first pushing block.When described first pushing block moves along described first guide rail forward, described first pushing block is resisted against on described sample rack, promotes described sample rack to move;When described first pushing block reversely moves along described first guide rail, described first pushing block is rotated outside sample rack by the stop of described sample rack, the most described main spring stretches, when described first pushing block leaves this sample rack, described first pushing block homing under the effect of described main spring.Sample rack can be blocked and push forward by the first pushing block of this connection main spring, and during reset, this first pushing block departs from sample rack screens, is received by spring effect, again pushes next sample rack.
Wherein in an embodiment, described sampling device also includes the emergency treatment frame for placing emergency treatment sample tube, and described emergency treatment is set up in described sampling position side.By the setting of emergency treatment frame, can detect with the sample of priority treatment emergency treatment frame, omnidistance realization full-automation detection is analyzed to make this immune quantitative analyser to guarantee, supports again the process of urgent sample, has the advantage that automaticity is high, flexible.
Wherein in an embodiment, described sample rack is provided with stopper slot or limit convex, and described sample introduction platform is provided with the limit convex or stopper slot matched with described stopper slot or limit convex, described stopper slot or limit convex and arranges along described sample rack moving direction.By snapping in stopper slot by limit convex, can prevent sample rack from the danger be inverted, topple occurring.
Wherein in an embodiment, described sampling device also includes that unloading equipment, described unloading equipment include unloading carrying platform, unloading drives motor and unloading pushing block, and described unloading drives motor to drive described unloading pushing block to move;Unloading on carrying platform described in moving under the promotion of described unloading pushing block extremely through the sample rack of over sampling position, described unloading platform edges is provided with position limiting fence.By the use of this unloading equipment, the sample that will have detected unloading, then it is arranged to sample introduction platform, carries out follow-up sample detection, it is achieved that the detection mode of continuous-flow type, there is detection efficiency height and convenient advantage.
Wherein in an embodiment, described unloading platform edges is provided with position limiting fence.By the use of position limiting fence, it is to avoid test tube rack is toppled over by unloading carrying platform.
Compared with prior art, this utility model has the advantages that
Sampling device of the present utility model, promotes sample rack X-axis in the horizontal direction and Y-axis motion respectively, namely is respectively longitudinal action and crosswise movement such that it is able to automatically, flexibly by sample tube be transported to sample position by position to be checked.
And by the setting of emergency treatment frame, can detect with the sample of priority treatment emergency treatment frame, improve the motility of this sampling device, be adapted to the clinical requirement to emergency treatment sample emergent management.
Also by the use of unloading equipment, the sample that will have detected unloading, then it is arranged to sample introduction platform, carries out follow-up sample detection, it is achieved that the detection mode of continuous-flow type, there is detection efficiency height and convenient advantage.
Accompanying drawing explanation
Fig. 1 is sampling device structural representation in embodiment 1;
Fig. 2 is the first connecting gear structural representation in embodiment 1;
Fig. 3 is the second connecting gear structural representation in embodiment 1;
Fig. 4 is emergency treatment shelf structure schematic diagram in embodiment 1;
Fig. 5 is immune quantitative analyser explosive view in embodiment 2;
Fig. 6 is immune quantitative analyser structural representation in embodiment 2;
Fig. 7 is immune quantitative analyser top view in embodiment 2;
Fig. 8 is incubating device structural representation in embodiment 2;
Fig. 9 is to play mechanism for card structural representation in embodiment 2;
Figure 10 is injecting pump structure schematic diagram in embodiment 2;
Figure 11 is mixing cup structure schematic diagram in embodiment 2;
Figure 12 is to sample driving means and puncture needle driving device structure schematic diagram in embodiment 2;
Figure 13 is buffer chamber structure schematic diagram in embodiment 2;
Figure 14 is evenly mixing device structural representation in embodiment 2;
Figure 15 is reagent card chamber structure schematic diagram in embodiment 2;
Figure 16 is reagent card transport conveyor constructions schematic diagram in embodiment 2;
Figure 17 is oscillating uniform device structural representation in embodiment 2;
Wherein: 100. sampling devices;110. sample rack;111. stopper slot;112. limit convex;120. sample introduction platforms;130. second sample introduction connecting gears;140. first sample introduction connecting gears;141. first pushing blocks;142. main spring;150. emergency treatment framves;161. unload carrying platform;200. incubating device;210. rotating disk;211. incubation slot;220. enter screens;230. loading positions;240. detecting position;250. play screens;251. the 3rd transmission bands;252. play fastener;253. the 3rd guide rails;260. give up Ka Cang;300. sampler;310. puncture needle;320. puncture driving means;330. sampling driving means;340. mixing cups;350. buffer storehouses;360. sampling positions;371. gas generating unit;372. positive displacement pump;373. gas piping;374. discharging tube;375. gas trap;376. tapping valve;377. negative-pressure cup;400. data acquisition unit;510. reagent card storehouses;511. reagent draw-in grooves;520. reagent card conveyer devices;521. the 7th transmission bands;522. the 7th guide rails;523. push jack;600. information read device;700. oscillating uniform device;710. clamping device;720. telecontrol equipment;730. lifting device.
Detailed description of the invention
For the ease of understanding the present invention, below with reference to relevant drawings, the present invention is described more fully.Accompanying drawing gives presently preferred embodiments of the present invention.But, the present invention can realize in many different forms, however it is not limited to embodiment described herein.On the contrary, providing the purpose of these embodiments is to make the understanding to the disclosure more thorough comprehensively.
It should be noted that be referred to as " being fixed on " another element when element, it can be directly on another element or can also there is element placed in the middle.When an element is considered as " connection " another element, and it can be to be communicates directly to another element or may be simultaneously present centering elements.
Unless otherwise defined, all of technology used herein is identical with the implication that the those skilled in the art belonging to the present invention are generally understood that with scientific terminology.The term used the most in the description of the invention is intended merely to describe the purpose of specific embodiment, it is not intended that in limiting the present invention.Term as used herein "and/or" includes the arbitrary and all of combination of one or more relevant Listed Items.
Embodiment 1
A kind of sampling device for immune quantitative analyser, as shown in Figure 1, sampling device includes for placing the sample rack 110 of sample tube, sample introduction platform 120, sample introduction connecting gear and system control module, described sample rack 110 is placed on described sample introduction platform 120, and can be transported to sample position 360 by position to be checked by sample tube under the effect of described sample introduction connecting gear.
In the present embodiment, described sample rack 110 is provided with stopper slot 111, and described sample introduction platform 120 is provided with the limit convex 112 matched with described stopper slot 111, and described limit convex 112 is arranged along described sample rack 110 moving direction.By snapping in stopper slot 111 by limit convex 112, can prevent sample rack 110 from the danger be inverted, topple occurring.
In the present embodiment, described sample introduction connecting gear includes the first connecting gear 140 and the second connecting gear 130.
As in figure 2 it is shown, described first connecting gear 140 includes the first driving motor, the first transmission band, the first pushing block 141 and the first guide rail, described first drives motor to drive described first pushing block 141 to move along described first guide rail by described first transmission band.As shown in Figure 6, described second connecting gear 130 includes the second driving motor, the second transmission band, the second pushing block and the second guide rail, and described second drives motor to drive described second pushing block to move along described second guide rail by described second transmission band.Described first drives motor and described second to drive motor all to electrically connect with described system control module.
Described first guide rail is arranged in mutually perpendicular directions with described second guide rail, and described first guide rail is arranged the most in the horizontal direction with described second guide rail, i.e. first connecting gear 140 and the second connecting gear 130 promote sample rack 110 X-axis in the horizontal direction and Y-axis motion respectively, described sample rack 110 can longitudinally move to described second pushing block under the promotion of described first pushing block 141 from position to be checked, then laterally moves to sample position 360 under the promotion of the second pushing block.
It should be understood that connecting gear also can take other modes such as mechanical hand etc. to build, it is only necessary to can just sample tube be transported to sample position by position to be checked.But said structure has Stability Analysis of Structures, reliable advantage.
In the present embodiment, described first connecting gear also includes cross bar and main spring 142, described cross bar is installed on described first transmission band, described first pushing block 141 has two pieces, corresponding with described sample rack 110 two ends respectively, and two pieces of described first pushing blocks 141 are rotating is installed on described cross bar two ends, and described main spring 142 two ends are individually fixed on described cross bar and described first pushing block 141.When described first pushing block 141 moves along described first guide rail forward, described first pushing block 141 is resisted against on described sample rack 110, promotes described sample rack 110 to move;When described first pushing block 141 reversely moves along described first guide rail, described first pushing block 141 is rotated outside sample rack by the stop of described sample rack 110, the most described main spring 142 stretches, when described first pushing block 141 leaves this sample rack, described first pushing block 141 homing under the effect of described main spring 142.Sample rack can be blocked and push forward by the first pushing block 141 of this connection main spring 142, and during reset, this first pushing block departs from sample rack screens, is received by spring effect, again pushes next sample rack.
In view of Clinical detection needs to face the demand of urgent sample process, in the present embodiment, described sampling device also includes the emergency treatment frame 150 for placing emergency treatment sample tube, as shown in Figure 7, described sampling position 360 side is located at by described emergency treatment frame 150, described puncture needle 310 can under the effect of described sampling driving means 330 emergency treatment frame 150, sampling position 360, buffer storehouse 350, mixing cup 340 and loading position 230 between move.
By the setting of emergency treatment frame, can detect with the sample of priority treatment emergency treatment frame, make this immune quantitative analyser can either realize full-automatic detection and analyze, support again the process of urgent sample, there is automaticity height, flexibly advantage.
In order to realize the detection of continuous-flow type, in the present embodiment, described sampling device also includes unloading equipment, as it is shown in figure 1, described unloading equipment includes unloading carrying platform 161, unloading drives motor and unloading pushing block, described unloading drives motor to drive described unloading pushing block to move;Through the sample rack 110 of over sampling position 360 under the promotion of described unloading pushing block mobile to described in unload on carrying platform 161, described in unload carrying platform 161 edge and be provided with position limiting fence.By the use of this unloading equipment, the sample that will have detected unloading, then it is arranged to sample introduction platform, carries out follow-up sample detection, it is achieved that the detection mode of continuous-flow type, there is detection efficiency height and convenient advantage.
Embodiment 2
A kind of immune quantitative analyser, as illustrated in figs. 5-7, including: the sampling device of embodiment 1, incubating device 200, sampler 300, data acquisition unit 400, reagent card device and system control module.
As shown in Figure 8, incubating device 200 includes rotating disk 210 and rotary disc driving mechanism, the incubation slot 211 being radially provided with some receiving reagent cards of described rotating disk 210, one end of described incubation slot 211 extends to the edge of described rotating disk 210, described rotating disk 210 can rotate around center of turntable under the drive of described rotary disc driving mechanism, makes described incubation slot 211 rotate to different angles and is positioned at into screens 220, loading position 230, detecting position 240 or plays screens 250.
In the present embodiment, described rotary disc driving mechanism also includes code-disc, turns disk-drive motor, drivewheel, reduction driven wheel, the described disk-drive motor that turns is by described drivewheel, described reduction driven wheel driving turntable 210, and described system control module controls the rotational angle of described rotating disk by described code-disc.Thus it is precisely controlled the rotational angle of rotating disk 210, improve overall co-ordination degree and the accuracy of instrument.
Being provided with positive stop spring plate in described incubation slot 211, described positive stop spring plate is arranged at incubation slot 211 medial wall, for being fixed reagent card position.Positive stop spring plate is arranged at the medial wall of incubation slot, can either good fixating reagent card, the most do not hinder reagent card slipping into and skidding off at this incubation slot.
In the present embodiment, described incubating device also includes playing mechanism for card, useless card storehouse 260 and attemperating unit.
Playing mechanism for card described in as it is shown in figure 9, to include the 3rd driving motor, the 3rd transmission band 251, play fastener 252 and the 3rd guide rail 253, the described 3rd drives motor to electrically connect with described system control module;Described 3rd drive motor by described 3rd transmission band 251 drive described in play fastener 252 and move along described 3rd guide rail 253, described fastener 252 of playing is arranged at and plays, with described, the position that screens 250 is corresponding, described 3rd guide rail 253 being radially arranged along described rotating disk, make described in play fastener 252 and can promote and be positioned at the reagent card playing screens 250 at described incubation slot 211 to rotating disk 210 boundary slip.The opening in described useless card storehouse 260 is located at described rotating disk 210 edge, and with described to play screens 250 corresponding.
By playing the effect of mechanism for card, the spent reagent card after detection is kicked out of incubation slot 211, vacates incubation slot position, treat that subsequent detection is automatically loaded new reagent card.The spent reagent card kicked out of then is directly entered in useless card storehouse 260, it is ensured that clean environment.
Described incubating device 200 also includes that attemperating unit, described attemperating unit include heating member, temperature sensor and for avoiding the overheat awitch of continuous heating.By the use of attemperating unit, the accurate temperature controlling incubating device, reach preferably to hatch effect.
nullSampler 300 includes puncture needle 310、Puncture driving means 320、Sampling driving means 330、Probe tube、Sampling valve、Syringe pump (as shown in Figure 10)、For the mixing cup 340 (as shown in figure 11) of sample mix with deposit the buffer storehouse 350 of buffer,Described puncture needle 310 connects described syringe pump by described probe tube,Described sampling valve is arranged on described probe tube,Described puncture needle 310 is installed in described puncture driving means 320,And can move up and down under the effect of this puncture driving means 320 and to puncture,Described puncture driving means 320 is installed in described sampling driving means 330,And described puncture needle 310 can be made under the effect of this sampling driving means 330 in sampling position 360、Buffer storehouse 350、Switch between mixing cup 340 and loading position 230.
Further, use puncture needle to draw liquid sample, it is not necessary to be opened by sample tube lid, thus avoid whole blood sample to be exposed to the problem that air produces layering.
In the present embodiment, as shown in figure 12, described puncture needle driving means 320 includes that 4 wheel driven galvanic electricity machine, the 4th transmission band, the 4th guide rail and the 4th connector, described 4 wheel driven galvanic electricity machine electrically connect with described system control module;Described 4 wheel driven galvanic electricity machine drives described 4th connector to move along the 4th guide rail by described 4th transmission band, and described 4th guide rail is vertically arranged, and described puncture needle is installed on described 4th connector;Thrusting for the ease of puncture needle, the lid of described sample cell should arrange the penetrating area that soft elastomeric material is made.
Described sampling driving means 330 includes the 5th driving motor, the 5th transmission band, the 5th guide rail and the 5th connector, and the described 5th drives motor to electrically connect with described system control module;Described 5th drives motor to drive described 5th connector to move along the 5th guide rail by described 5th transmission band, and described puncture driving means 320 is installed on described 5th connector;Described emergency treatment frame 150, sampling position 360, buffer storehouse 350, mixing cup 340 and loading position 230 are arranged along described 5th guide rail bearing of trend.
Above-mentioned sampling driving means 330 drives puncture needle driving means 320 cleaning storehouse, sampling position 360, buffer storehouse 350, moving between mixing cup 340 and loading position 230, again by puncture needle driving means 320, puncture needle is made to draw the buffer extremely mixing cup being positioned at sampling position 360 sample tube testing sample, being loaded on buffer storehouse 350 accurately, after fully mixing, then draw diluted sample to loading position 230 the precalculated position loading at reagent card.
As shown in figure 13, described buffer storehouse 350 has six bin levels, and wherein four supply to place the buffer corresponding with dissimilar reagent card, and other two then places acid, alkaline cleaner.The quantity of position in storehouse can also be adjusted according to actual needs.Further, after buffer is finished, starts the prompting function in this buffer storehouse, send signal, in order to operator supplement in time.
In the present embodiment, as shown in figure 14, described sampler 300 also includes evenly mixing device, this evenly mixing device includes that gas generating unit 371, positive displacement pump 372, gas piping 373, discharging tube 374, gas trap 375 and tapping valve 376, described gas generating unit 371, positive displacement pump 372, gas trap 375 and tapping valve 376 all electrically connect with described system control module;Described mixing cup 340 (as shown in figure 11) bottom is connected by described gas piping 373 with described gas generating unit 371, described gas trap 375 is located on this gas piping 373, being connected with described discharging tube 374 by described positive displacement pump 372 bottom described mixing cup 340, described tapping valve 376 is located on this discharging tube 374.In mixing cup 340, it is filled with air, the liquid of mixing cup is formed bubble, by the floating of bubble with rupture, sample is fully mixed.
In the present embodiment, described evenly mixing device also includes that negative-pressure cup 377, described negative-pressure cup 377 are installed on the pipeline between described positive displacement pump 372 and described tapping valve 376.Negative pressure is stored, it is to avoid positive displacement pump 372 is in normally open, to extend the service life of positive displacement pump by negative-pressure cup 377.
Data acquisition unit 400 includes that light source module, photoelectric conversion module, described light source module are pointed to the reagent card predeterminable area of detecting position and launch the exciting light of predetermined wavelength, and described photoelectric conversion module is collected scattered light that this reagent card sends and is converted to the signal of telecommunication.This data acquisition unit is arranged according to routine techniques.
Reagent card device include reagent card storehouse 510 and reagent card conveyer device 520, described reagent card conveyer device 520 will be located in described reagent card storehouse outlet reagent card push to be positioned at the described incubation slot 211 into screens 220.
In the present embodiment, as shown in figure 15, described reagent card storehouse 510 includes that the 6th drives motor, the 6th transmission band, the 6th connector, the 6th guide rail and four for placing the reagent draw-in groove 511 of reagent card, and the described 6th drives motor to electrically connect with described system control module;Four described reagent draw-in grooves 511 are mounted side by side on described 6th connector, and the reagent card of these four described reagent draw-in grooves 511 exports and is located at bottom this reagent draw-in groove 511, described 6th drives motor described 6th connector can be driven to move along described 6th guide rail by described 6th transmission band, makes described reagent card conveyer device 520 corresponding to different reagent draw-in groove outlets;
As shown in figure 16, described reagent card conveyer device 520 includes the 7th driving motor, the 7th transmission band the 521, the 7th connector and the 7th guide rail 522, and the described 7th drives motor to electrically connect with described system control module;On described 7th connector, push jack 523 is installed, described 7th drives motor to drive described 7th connector to move along described 7th guide rail 522 by described 7th transmission band 521, makes described push jack 523 push to be positioned at the incubation slot 210 into screens 220 by reagent draw-in groove 511 outlet by reagent card.
Mentioned reagent card storehouse 510 and reagent card conveyer device 520 cooperate, can smooth must the reagent card in reagent card storehouse 510 be pushed in incubation slot 210, and can be by the 6th driving motor, the 6th transmission band, the 6th connector and the effect of the 6th guide rail, make described reagent card conveyer device 520 corresponding to different reagent draw-in groove outlets, the reagent card of detection disparity items can be loaded in different reagent draw-in grooves, thus different detection projects can be carried out by selecting different reagent cards.
Being provided with the rib matched with the breach that detection project reagent card is provided with accordingly in described reagent draw-in groove, in order to limit type and the placement direction of reagent card, the accuracy for subsequent detection provides safeguard.It should be understood that above-mentioned rib can use any shape, such as triangle etc., it is only necessary to match with the breach on corresponding reagent card.
In the present embodiment, described reagent card storehouse is additionally provided with position limiting slide block, and this position limiting slide block can slide up and down in described reagent draw-in groove along guide rail.When the reagent card in reagent draw-in groove does not load the most whole reagent draw-in groove, this position limiting slide block can down slide and fix reagent card in box, when placing reagent card negligible amounts in being used for avoiding box, and the phenomenon that reagent card glances off or reverses.Further, after reagent card is finished, starts the prompting function in this reagent card storehouse, send signal, in order to operator supplement.
System control module, including input module, display module and data processing module, described input module and described display module electrically connect with described data processing module, and described system control module controls described sample introduction connecting gear, rotary disc driving mechanism, puncture driving means 320, sampling driving means 330, sampling valve, syringe pump, light source module, photoelectric conversion module and reagent card conveyer device 520 and runs.
The Main Function of display module is by operational order, and procedural information, test result show, this display module and input module can be integrated in instrument, and its main hardware includes display screen, touch screen, display lamp etc..Data processing module is responsible for the scheduling of whole system, is controlled, monitors, and carries out man-machine interaction and troubleshooting in time, is mainly made up of hardware board and software system.
In the present embodiment, this immune quantitative analyser also includes cleaning device, described cleaning device includes cleaning storehouse and discharging storehouse, the bottom in described cleaning storehouse is provided with the cleanout fluid inlet for connecting cleanout fluid pipeline, the top in described cleaning storehouse is provided with leakage fluid dram, described leakage fluid dram is by discharging storehouse described in cleanout fluid flow passage, described discharge storehouse can connect with negative pressure system and have negative pressure and extracted out by the cleanout fluid in described cleaning storehouse;Described cleaning storehouse is additionally provided with air intlet and air outlet slit;Described puncture needle can clean storehouse, sampling position, buffer storehouse, move between mixing cup and loading position.
It should be understood that may be used without disposable Tip head, diluted cup etc. to realize stopping the purpose of each sample cross-contamination.But, by the effect of above-mentioned cleaning device, it is not necessary to use the consumptive materials such as disposable imbibition rifle head (Tip head), the advantage with low cost, environmental protection.
In the present embodiment, this immune quantitative analyser also includes information read device 600, and described information read device is for reading the bar code information of the sample tube entering sampling position, and this information read device electrically connects with described system control module.The information of above-mentioned sample tube includes the patient data providing sample, detection project etc..It should be understood that as without this information read device, nor affect on the detection analysis work of this analyser.But read the information of sample to be tested pipe with information read device, thus call corresponding project detection program, different project detections can be carried out on an analyser.
In the present embodiment, this immune quantitative analyser also includes oscillating uniform device 700, and sample tube is transported to successively shake up position and sampling position by described sample introduction connecting gear by position to be checked;As shown in figure 17, described oscillating uniform device 700 includes being positioned at the clamping device 710 of the sample tube shaking up position, for rocking telecontrol equipment 720 and the lifting device 730 of sample tube for clamping, described telecontrol equipment 720 one end connects clamping device 710, the other end connects lifting device 730, described telecontrol equipment 720 and described clamping device 710 can move under in the vertical direction under the effect of described lifting device 730, and described telecontrol equipment 720 and lifting device 730 electrically connect with described system control module.By the use of above-mentioned oscillating uniform device, testing liquid sample is fully mixed before sampling, improves detection accuracy.
In the present embodiment, described clamping device 710 includes sample pipe clamp and connector, and it is spacing that described oscillating uniform device is provided with pin.Collision interference in being possible to prevent sample cell to move with frame or other device parts during shaking up.And described sample pipe clamp is made up of hard elastic material, to adapt to various sizes of sample tube.
The immune quantitative analyser using the present embodiment carries out immune quantitative analysis, and each process step is as follows:
The sample tube that will be equipped with testing liquid sample is positioned on sample rack, described sample introduction connecting gear be transported to sample position by position to be checked by this sample tube;
Under the control of system control module, described puncture needle 310 is under the effect of described sampling driving means 330, mobile to buffer storehouse 350, draw quantitative buffer, moving again to sample above position 360, puncture the lid being positioned at sampling position sample tube, testing liquid sample drawn by the leading lower puncture needle 310 at syringe pump, moved to mixing cup 340 by sampling position 360 under the effect of sampling driving means 330 subsequently, buffer is injected in described mixing cup 340 together with testing liquid sample;
Described gas generating unit 371 produces gas, opens described gas trap 375, is filled with air in mixing cup 340, forms bubble in the liquid of mixing cup 340, by the floating of bubble with rupture, fully mixes sample.
Meanwhile, reagent card conveyer device 520 will be located in the reagent card of described reagent card storehouse 510 outlet and is pushed to be positioned at the incubation slot 211 into screens 220, and this reagent card, along with the rotation of rotating disk 210, turns to loading position 230 from entering screens 220;
Control puncture needle 210 to draw and the mixed sample solution of buffer, drop on the above-mentioned reagent card being positioned at loading position 230;
The reagent card of above-mentioned dropping sample solution is hatched after carrying out immunochromatography reaction, along with the rotation of rotating disk 210, turns to detecting position 240 from loading position 230, by described data acquisition unit 400 acquisition testing result data, and is sent to system control module.
Subsequently, this reagent card detected is after detecting position 240 is by described data acquisition unit 400 acquisition testing result data, rotation along with rotating disk 210, turn to play screens 250 from detecting position 240, described play fastener 252 promote be positioned at the reagent card playing screens 250 to rotating disk 210 boundary slip until this reagent card skids off incubation slot 211, this vacant incubation slot 211 can rotate with rotating disk 210 subsequently, again turns to into screens 220, for subsequent detection from playing screens 250.
During the continuous cycle detection of instrument, the sample of emergent management if needed, after then will be equipped with needing the sample tube of the testing liquid sample immediately measured to be positioned over emergency treatment frame 150, under the control of system control module, described puncture needle 310 moves to described emergency treatment frame 150, and move down and puncture the lid being positioned at emergency treatment frame 150 sample tube, draw this liquid sample and carry out subsequent detection.
Each technical characteristic of embodiment described above can combine arbitrarily, for making description succinct, the all possible combination of each technical characteristic in above-described embodiment is not all described, but, as long as the combination of these technical characteristics does not exist contradiction, all it is considered to be the scope that this specification is recorded.
Embodiment described above only have expressed several embodiments of the present utility model, and it describes more concrete and detailed, but therefore can not be interpreted as the restriction to utility model patent scope.It should be pointed out that, for the person of ordinary skill of the art, without departing from the concept of the premise utility, it is also possible to make some deformation and improvement, these broadly fall into protection domain of the present utility model.Therefore, the protection domain of this utility model patent should be as the criterion with claims.

Claims (6)

1. the sampling device for immune quantitative analyser, it is characterized in that, including for placing the sample rack of sample tube, sample introduction platform, sample introduction connecting gear and system control module, described sample rack is placed on described sample introduction platform, and can be transported to sample position by position to be checked by sample tube under the effect of described sample introduction connecting gear;
Described sample introduction connecting gear includes the first connecting gear and the second connecting gear;
Described first connecting gear includes the first driving motor, the first transmission band, the first pushing block and the first guide rail, and described first drives motor to drive described first pushing block to move along described first guide rail by described first transmission band;
Described second connecting gear includes the second driving motor, the second transmission band, the second pushing block and the second guide rail, and described second drives motor to drive described second pushing block to move along described second guide rail by described second transmission band;
Described first drives motor and described second to drive motor all to electrically connect with described system control module;
Described first guide rail is arranged in mutually perpendicular directions with described second guide rail, and described first guide rail is arranged the most in the horizontal direction with described second guide rail, described sample rack can move to described second pushing block from displacement to be checked under the promotion of described first pushing block, then moves to sampling position under the promotion of the second pushing block.
Sampling device the most according to claim 1, it is characterized in that, described first connecting gear also includes cross bar and main spring, described cross bar is installed on described first transmission band, described first pushing block has two pieces, corresponding with described sample rack two ends respectively, and two pieces of described first pushing blocks are rotating is installed on described cross bar two ends, and described main spring two ends are individually fixed on described cross bar and described first pushing block.
Sampling device the most according to claim 1, it is characterised in that described sampling device also includes the emergency treatment frame for placing emergency treatment sample tube, described emergency treatment is set up in described sampling position side.
Sampling device the most according to claim 1, it is characterized in that, described sample rack is provided with stopper slot or limit convex, and described sample introduction platform is provided with the limit convex or stopper slot matched with described stopper slot or limit convex, described stopper slot or limit convex and arranges along described sample rack moving direction.
5. according to the sampling device described in any one of claim 1-4, it is characterised in that also including that unloading equipment, described unloading equipment include unloading carrying platform, unloading drives motor and unloading pushing block, described unloading drives motor to drive described unloading pushing block to move;Unload on carrying platform described in moving under the promotion of described unloading pushing block extremely through the sample rack of over sampling position.
Sampling device the most according to claim 5, it is characterised in that described unloading platform edges is provided with position limiting fence.
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107063830A (en) * 2017-03-03 2017-08-18 迪瑞医疗科技股份有限公司 A kind of vaginal fluid sample pre-treatment device
CN107167344A (en) * 2017-07-05 2017-09-15 四川迈克生物医疗电子有限公司 Inhale sample system and sample analyser
CN108572173A (en) * 2018-07-11 2018-09-25 珠海中信兴通科技有限公司 Drug detecting instrument
CN108717115A (en) * 2018-05-29 2018-10-30 陈金凤 A kind of detection device of medicine bio-chemical detector
CN108732097A (en) * 2018-05-29 2018-11-02 陈金凤 A kind of optical detection apparatus of medicine bio-chemical detector
CN109324200A (en) * 2018-12-12 2019-02-12 深圳普门科技股份有限公司 Sample analyser
CN109324202A (en) * 2018-12-12 2019-02-12 深圳普门科技股份有限公司 Autosampler can be cascaded
CN114324812A (en) * 2022-03-11 2022-04-12 安徽海峰分析测试科技有限公司 Water quality heavy metal detection device and method

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107063830A (en) * 2017-03-03 2017-08-18 迪瑞医疗科技股份有限公司 A kind of vaginal fluid sample pre-treatment device
CN107063830B (en) * 2017-03-03 2020-06-02 迪瑞医疗科技股份有限公司 Vaginal secretion sample pretreatment device
CN107167344A (en) * 2017-07-05 2017-09-15 四川迈克生物医疗电子有限公司 Inhale sample system and sample analyser
CN108732097B (en) * 2018-05-29 2020-10-09 刘庆玲 Optical detection device of medical biochemical detector
CN108717115A (en) * 2018-05-29 2018-10-30 陈金凤 A kind of detection device of medicine bio-chemical detector
CN108732097A (en) * 2018-05-29 2018-11-02 陈金凤 A kind of optical detection apparatus of medicine bio-chemical detector
CN108572173A (en) * 2018-07-11 2018-09-25 珠海中信兴通科技有限公司 Drug detecting instrument
CN108572173B (en) * 2018-07-11 2022-02-01 珠海中信兴通科技有限公司 Drug detector
CN109324200A (en) * 2018-12-12 2019-02-12 深圳普门科技股份有限公司 Sample analyser
CN109324202A (en) * 2018-12-12 2019-02-12 深圳普门科技股份有限公司 Autosampler can be cascaded
CN109324200B (en) * 2018-12-12 2022-04-01 深圳普门科技股份有限公司 Sample analyzer
CN114324812A (en) * 2022-03-11 2022-04-12 安徽海峰分析测试科技有限公司 Water quality heavy metal detection device and method

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