CN110530867A - The micro- test tube reaction cup of cassette and the full-automatic test tube detection method for utilizing the reaction cup - Google Patents

The micro- test tube reaction cup of cassette and the full-automatic test tube detection method for utilizing the reaction cup Download PDF

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Publication number
CN110530867A
CN110530867A CN201910961919.XA CN201910961919A CN110530867A CN 110530867 A CN110530867 A CN 110530867A CN 201910961919 A CN201910961919 A CN 201910961919A CN 110530867 A CN110530867 A CN 110530867A
Authority
CN
China
Prior art keywords
test tube
micro
reaction cup
cassette
deck
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910961919.XA
Other languages
Chinese (zh)
Inventor
吴旻
李永峰
单宏伟
丁玲玲
张东
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Bessel Bioengineering Co Ltd
Original Assignee
Jiangsu Bessel Bioengineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Bessel Bioengineering Co Ltd filed Critical Jiangsu Bessel Bioengineering Co Ltd
Priority to CN201910961919.XA priority Critical patent/CN110530867A/en
Publication of CN110530867A publication Critical patent/CN110530867A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications

Abstract

The invention discloses a kind of micro- test tube reaction cup of cassette and using the full-automatic test tube detection method of the reaction cup, the micro- test tube reaction cup of cassette is clamped including deck and in a row several micro test tubes being arranged on deck.Reaction cup clever structure of the invention, traditional test tube is become miniature, not only save tube material, conducive to reduction medical waste, it is more environmentally-friendly, and, by the reaction cup, utilize detection method and detection system of the invention, it can be by the detection method of sample by traditional qualitative, artificial eye judgement is converted to quantitative machine interpretable, reduce the dependence to doctor's interpretation experience, it has been greatly reduced False Rate, reduce reagent dosage, substantially increase interpretation accuracy, and it can be with batch operation, greatly accelerate treating capacity, the processing time is saved, it is practical, it is worthy to be popularized.

Description

The micro- test tube reaction cup of cassette and the full-automatic test tube detection method for utilizing the reaction cup
Technical field
The invention belongs to detection field more particularly to a kind of micro- test tube reaction cup of cassette and utilize the full-automatic of the reaction cup Test tube detection method.
Background technique
In the prior art, blood testing generallys use test tube method and carries out qualitative analysis out as a result, being with normal test tube It is manually loaded, the movement such as outstanding, interpretation, but the operation and interpretation experience of this method heavy dependence doctor again, neophyty operation It is easy to appear interpretation result error, and test tube dosage is very big, discarded test tube is also unfavorable to environmental protection.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of micro- test tube reaction cups of cassette.
The present invention is achieved through the following technical solutions:
The micro- test tube reaction cup of cassette is clamped including deck and in a row several micro test tubes being arranged on deck.
Preferably, a row or two rows of micro test tubes are equipped on the deck, when deck is equipped with two rows of micro test tubes When, two rows between, separated by opaque partition.
Preferably, the height of micro test tube is 20mm-30mm, diameter 5mm-10mm.
Preferably, the number for being in a row clamped one row of micro test tube being arranged on deck is 3-10.
Preferably, Blood grouping reagent or serum detection reagent are placed in the micro test tube, it is more preferably, described micro- Type test tube top is equipped with Sealing piece.
Preferably, the deck and the micro test tube being arranged on deck are integrally formed.
Preferably, the material of the deck and micro test tube is medical plastic, more preferably, the medical plastic includes poly- Ethylene.
Preferably, the micro test tube is evenly distributed, and top is in same level height.
The invention also discloses a kind of full-automatic test tube detection methods using the micro- test tube reaction cup of above-mentioned cassette, comprising as follows Step:
(1) sample absorbing device sample drawn and salt water, are made into cell suspension, and it is anti-that the micro- test tube of cassette is added in subsequent abstraction reaction reagent It answers in the micro test tube in cup;
(2) it moves to take device the micro- test tube reaction cup of cassette is put into centrifuge and be centrifuged;
(3) after the completion of being centrifuged, the transition card test tube reaction cup that declines enters multiple suspension mechanism;
(4) the artificial multiple outstanding movement of multiple suspension mechanism simulation is hanged again;
(5) result interpretation is carried out using image recognition.
Preferably, the sample is blood sample.
The invention also discloses a kind of detection systems for realizing above-mentioned full-automatic test tube detection method, including sample application Device, centrifuge, multiple hanging is set and pattern recognition device, and the centrifuge and multiple hanging set and be equipped with installation placement cassette The bracket of micro- test tube reaction cup.This detection system, which passes through, quantitatively instills blood sample into the micro test tube with detection reagent, It is then placed in centrifuge and is centrifuged, subsequently hanged by simulating the multiple hanging of artificial movement outstanding again and setting, stood after completing multiple hang again It is taken pictures by pattern recognition device to the micro- test tube reaction cup of cassette and is carried out according to the standard pattern inputted in advance after a certain period of time Analysis is compared, finally provides in batches as a result, this method not only greatly accelerates treating capacity, saved the processing time, passes through the party Traditional qualitative experiment is transformed to quantitative experiment, reduces the dependence to doctor's interpretation experience by method, has been greatly reduced accidentally Sentence rate, also because test tube is micro test tube, the medicament that uses is less and controls accurate sample-adding amount, thus also greatly reduces medicament Dosage, reduce reagent cost and test tube cost.
Preferably, the multiple hanging that the multiple hanging is set to the artificial multiple outstanding movement of simulation is set.
Preferably, the multiple hanging of the artificial multiple outstanding movement of simulation is set, including pedestal and it is set on the base multiple outstanding Bracket, the bracket that hangs again are swung by servo motor driving, described to hang the mountable micro- test tube reaction of placement cassette on bracket again Cup.The multiple hanging is set, and by the way that angle, amplitude is arranged, speed hangs movement to reappear again by hand.
More preferably, the bracket both ends that hang again are set on the base by bearing and bearing block, and the servo motor is fixed On pedestal.
Preferably, described image identification device is AI imaging analysis instrument.
The beneficial effects of the present invention are:
Traditional test tube is become miniature, not only saves tube material by reaction cup clever structure of the invention, is conducive to reduce doctor Rubbish is treated, it is more environmentally-friendly, moreover, by the reaction cup, it, can be by sample using detection method and detection system of the invention Detection method is converted to quantitative machine interpretable by traditional qualitative, artificial eye judgement, reduces to doctor's interpretation experience It relies on, has been greatly reduced False Rate, has reduced reagent dosage, substantially increased interpretation accuracy, and can be with batch operation, greatly It accelerates treating capacity greatly, saved the processing time, it is practical, it is worthy to be popularized.
Detailed description of the invention
The present invention is described in detail by following specific embodiments and drawings for ease of explanation,.
Fig. 1 is that the deck of the micro- test tube reaction cup of cassette of the invention is equipped with the structural schematic diagram of row's micro test tube;
Fig. 2 is that multiple hanging of the invention sets the setting structure schematic diagram with pattern recognition device;
Fig. 3 is apparatus structure schematic diagram outstanding again of the invention.
Specific embodiment
As shown in Figure 1-3, the micro- test tube reaction cup 10 of cassette, if being arranged on deck 11 including deck 11 and clamping in a row Dry micro test tube 12.
On the deck 11, it is equipped with row's micro test tube, when deck is equipped with two rows of micro test tubes, between two rows, is led to Opaque partition is crossed to separate.In the present embodiment, the deck is equipped with row's micro test tube.
The height of micro test tube 12 is 20mm-30mm, diameter 5mm-10mm.
The number of one row's micro test tube 12 is 3-10, in the present embodiment, is 6.
Blood grouping reagent or serum detection reagent are placed in the micro test tube 12, the micro test tube top is equipped with Sealing piece.
The deck 11 and the micro test tube 12 being arranged on deck 11 are integrally formed.
The material of the deck 11 and micro test tube 12 is medical plastic, and the medical plastic includes polyethylene.
The micro test tube 12 is evenly distributed, and top is in same level height.
Using the full-automatic test tube detection method of the micro- test tube reaction cup of above-mentioned cassette, comprise the following steps:
(1) sample absorbing device sample drawn and salt water, are made into cell suspension, and it is anti-that the micro- test tube of cassette is added in subsequent abstraction reaction reagent It answers in the micro test tube in cup;
(2) it moves to take device the micro- test tube reaction cup of cassette is put into centrifuge and be centrifuged;
(3) after the completion of being centrifuged, the transition card test tube reaction cup that declines enters multiple suspension mechanism;
(4) the artificial multiple outstanding movement of multiple suspension mechanism simulation is hanged again;
(5) result interpretation is carried out using image recognition.
The sample is blood sample.
For realizing the detection system of above-mentioned full-automatic test tube detection method, including sample application device, centrifuge, multiple hanging 20 and pattern recognition device 30 are set, the centrifuge and multiple hanging, which are set, is equipped with the installation placement micro- test tube reaction cup of cassette on 20 10 bracket.The side of the final election device 20 far from pattern recognition device 30 is equipped with a background board 40, convenient for shooting.
This detection system, which passes through, quantitatively instills blood sample into the micro test tube with detection reagent, is then placed in centrifugation It is centrifuged in machine, is subsequently hanged again by simulating manually again the multiple hanging of outstanding movement and setting, complete to stand after hanging again and lead to after a certain period of time It crosses pattern recognition device to take pictures to the micro- test tube reaction cup of cassette and be compared according to the standard pattern inputted in advance, finally Batch provides as a result, this method not only greatly accelerates treating capacity, saved the processing time, in this way, traditional is determined Property experiment be transformed to quantitative experiment, reduce the dependence to doctor's interpretation experience, be greatly reduced False Rate, also because examination Pipe is micro test tube, the medicament that uses is less and controls accurate sample-adding amount, thus also greatly reduces the dosage of medicament, reduces Reagent cost and test tube cost.
It is that the artificial multiple multiple hanging for hanging movement of simulation is set that the multiple hanging, which sets 20,.
The multiple hanging sets 20, described to hang bracket 22 again including pedestal 21 and the bracket 22 outstanding again being arranged on pedestal 21 It is driven and is swung by servo motor 23, it is described to hang the mountable micro- test tube reaction cup 10 of placement cassette on bracket 22 again.The multiple hanging It sets, by the way that angle, amplitude is arranged, speed acts to reappear multiple hang by hand.
22 both ends of bracket that hang again are arranged on pedestal 21 by bearing and bearing block 24, and the servo motor 23 is fixed On pedestal 21.
Described image identification device 30 is AI imaging analysis instrument.
Traditional test tube is become miniature, not only saves tube material, conducive to subtracting by reaction cup clever structure of the invention Few medical waste, it is more environmentally-friendly, moreover, by the reaction cup, it, can be by sample using detection method and detection system of the invention This detection method is converted to quantitative machine interpretable by traditional qualitative, artificial eye judgement, reduces and passes through to doctor's interpretation The dependence tested, has been greatly reduced False Rate, reduces reagent dosage, substantially increases interpretation accuracy, and can grasp in batches Make, greatly accelerates treating capacity, saved the processing time, it is practical, it is worthy to be popularized.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any The change or replacement expected without creative work, should be covered by the protection scope of the present invention.Therefore, of the invention Protection scope should be determined by the scope of protection defined in the claims.

Claims (10)

1. the micro- test tube reaction cup of cassette, which is characterized in that including deck and in a row clamping be arranged on deck several are miniature Test tube.
2. the micro- test tube reaction cup of cassette according to claim 1, which is characterized in that on the deck, be equipped with a row or two Micro test tube is arranged, when deck is equipped with two rows of micro test tubes, between two rows, is separated by opaque partition.
3. the micro- test tube reaction cup of cassette according to claim 1, which is characterized in that the height of micro test tube is 20mm- 30mm, diameter 5mm-10mm.
4. the micro- test tube reaction cup of cassette according to claim 2, which is characterized in that in a row clamping is arranged in micro- on deck The number of one row of type test tube is 3-10.
5. the micro- test tube reaction cup of cassette according to claim 1, which is characterized in that be placed with blood group in the micro test tube Detection reagent or serum detection reagent.
6. the micro- test tube reaction cup of cassette according to claim 1, which is characterized in that the deck and be arranged on deck Micro test tube is integrally formed.
7. using the full-automatic test tube detection method of the micro- test tube reaction cup of cassette described in any one described in claim 1-6, It is characterized in that, comprises the following steps:
(1) sample absorbing device sample drawn and salt water, are made into cell suspension, and it is anti-that the micro- test tube of cassette is added in subsequent abstraction reaction reagent It answers in the micro test tube in cup;
(2) it moves to take device the micro- test tube reaction cup of cassette is put into centrifuge and be centrifuged;
(3) after the completion of being centrifuged, the transition card test tube reaction cup that declines enters multiple suspension mechanism;
(4) the artificial multiple outstanding movement of multiple suspension mechanism simulation is hanged again;
(5) result interpretation is carried out using image recognition.
8. a kind of detection system for realizing method of claim 7, including it is sample application device, centrifuge, multiple outstanding Device and pattern recognition device, the centrifuge and multiple hanging, which are set, is equipped with the branch that the micro- test tube reaction cup of cassette is placed in installation Frame.
9. detection system according to claim 8, which is characterized in that the multiple hanging is set to the artificial multiple outstanding movement of simulation Multiple hanging is set.
10. detection system according to claim 9, which is characterized in that the multiple hanging of the artificial multiple outstanding movement of simulation is set, Bracket is hanged again with what is be set on the base including pedestal, and the bracket that hangs again passes through servo motor driving swing, the branch outstanding again The mountable micro- test tube reaction cup of placement cassette on frame.
CN201910961919.XA 2019-10-11 2019-10-11 The micro- test tube reaction cup of cassette and the full-automatic test tube detection method for utilizing the reaction cup Pending CN110530867A (en)

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Application Number Priority Date Filing Date Title
CN201910961919.XA CN110530867A (en) 2019-10-11 2019-10-11 The micro- test tube reaction cup of cassette and the full-automatic test tube detection method for utilizing the reaction cup

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Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991002979A1 (en) * 1989-08-23 1991-03-07 Indicia Societe Civile D'etudes Et De Recherches (Scer) Method and device for rapidly assaying a plurality of samples containing an immunologically reactive substance
CN101581676A (en) * 2008-05-14 2009-11-18 基立福有限公司 Microtube reader device for the analysis of blood samples
US20130293706A1 (en) * 2011-01-25 2013-11-07 Hamilton Bonaduz Ag Optical analysis method for liquid in a sample container and analysis device for carrying out the method
CN203310842U (en) * 2013-06-06 2013-11-27 江苏克莱斯克生物技术有限公司 Full-automatic blood bank system
CN103852578A (en) * 2014-01-14 2014-06-11 白仲虎 Detachable batten for enzyme-linked immuno sorbent assay (ELISA) plate
CN105021808A (en) * 2015-08-10 2015-11-04 埃思生物科技(上海)有限公司 Micropore reaction cup stacking device and using method thereof
JP2016029347A (en) * 2014-07-25 2016-03-03 国立大学法人九州大学 Test tube fitting module and module for test tube
CN107202896A (en) * 2017-05-26 2017-09-26 江苏力博医药生物技术股份有限公司 A kind of quick detection IgG Subtypes reagent cards and preparation method thereof
CN206652524U (en) * 2017-03-15 2017-11-21 上海德孚生物医疗科技有限公司 Compatible type rack for test tube
CN107389957A (en) * 2017-06-28 2017-11-24 苏州长光华医生物医学工程有限公司 Micro-column gel card aggegation testing result identifying system and blood type analytical instrument
WO2019033312A1 (en) * 2017-08-16 2019-02-21 北京普利生仪器有限公司 Blood analyzer and control method therefor
CN211235559U (en) * 2019-10-11 2020-08-11 江苏贝索生物工程有限公司 Card type micro test tube reaction cup

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991002979A1 (en) * 1989-08-23 1991-03-07 Indicia Societe Civile D'etudes Et De Recherches (Scer) Method and device for rapidly assaying a plurality of samples containing an immunologically reactive substance
CN101581676A (en) * 2008-05-14 2009-11-18 基立福有限公司 Microtube reader device for the analysis of blood samples
US20130293706A1 (en) * 2011-01-25 2013-11-07 Hamilton Bonaduz Ag Optical analysis method for liquid in a sample container and analysis device for carrying out the method
CN203310842U (en) * 2013-06-06 2013-11-27 江苏克莱斯克生物技术有限公司 Full-automatic blood bank system
CN103852578A (en) * 2014-01-14 2014-06-11 白仲虎 Detachable batten for enzyme-linked immuno sorbent assay (ELISA) plate
JP2016029347A (en) * 2014-07-25 2016-03-03 国立大学法人九州大学 Test tube fitting module and module for test tube
CN105021808A (en) * 2015-08-10 2015-11-04 埃思生物科技(上海)有限公司 Micropore reaction cup stacking device and using method thereof
CN206652524U (en) * 2017-03-15 2017-11-21 上海德孚生物医疗科技有限公司 Compatible type rack for test tube
CN107202896A (en) * 2017-05-26 2017-09-26 江苏力博医药生物技术股份有限公司 A kind of quick detection IgG Subtypes reagent cards and preparation method thereof
CN107389957A (en) * 2017-06-28 2017-11-24 苏州长光华医生物医学工程有限公司 Micro-column gel card aggegation testing result identifying system and blood type analytical instrument
WO2019033312A1 (en) * 2017-08-16 2019-02-21 北京普利生仪器有限公司 Blood analyzer and control method therefor
CN211235559U (en) * 2019-10-11 2020-08-11 江苏贝索生物工程有限公司 Card type micro test tube reaction cup

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