CN110945123A - 生产可溶性重组人碱性成纤维细胞生长因子(rh-bFGF)的方法 - Google Patents
生产可溶性重组人碱性成纤维细胞生长因子(rh-bFGF)的方法 Download PDFInfo
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Abstract
提供了一种生产可溶性的重组人碱性成纤维细胞生长因子(rh‑bFGF)的方法，通过该方法获得的重组人碱性成纤维细胞生长因子(rh‑bFGF)，以及编码该重组人碱性成纤维细胞生长因子(rh‑bFGF)的突变核酸分子。
Description
PCT国内申请，说明书已公开。
Claims (11)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2017/089810 WO2018232745A1 (zh) | 2017-06-23 | 2017-06-23 | 生产可溶性重组人碱性成纤维细胞生长因子(rh-bFGF)的方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110945123A true CN110945123A (zh) | 2020-03-31 |
| CN110945123B CN110945123B (zh) | 2023-06-23 |
Family
ID=64735440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780092424.7A Active CN110945123B (zh) | 2017-06-23 | 2017-06-23 | 生产可溶性重组人碱性成纤维细胞生长因子(rh-bFGF)的方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11248032B2 (zh) |
| EP (1) | EP3643781A4 (zh) |
| JP (1) | JP7098724B2 (zh) |
| KR (1) | KR102428209B1 (zh) |
| CN (1) | CN110945123B (zh) |
| SG (1) | SG11201912790WA (zh) |
| WO (1) | WO2018232745A1 (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115975002A (zh) * | 2022-08-16 | 2023-04-18 | 广东普罗凯融生物医药科技有限公司 | 一种重组人碱性成纤维细胞生长因子及其制备方法与应用 |
| CN116889545A (zh) * | 2023-06-27 | 2023-10-17 | 上海腾瑞制药股份有限公司 | 一种重组人酸性成纤维细胞生长因子凝胶剂及其制备工艺 |
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| JP2003189865A (ja) * | 2001-12-26 | 2003-07-08 | Fuji Photo Film Co Ltd | 繊維芽細胞成長因子をコードする組み換えベクター |
| CN1448510A (zh) * | 2002-04-04 | 2003-10-15 | 北京三元基因工程有限公司 | 一种重组人碱性成纤维细胞生长因子的高效表达 |
| CN1733294A (zh) * | 2005-08-10 | 2006-02-15 | 南海朗肽制药有限公司 | 一种重组人碱性成纤维细胞生长因子凝胶剂及其制备方法 |
| CN102688479A (zh) * | 2012-06-20 | 2012-09-26 | 涂桂洪 | 预防干眼症的组合物、包括其的眼贴膜及该眼贴膜的制备方法 |
| CN103667329A (zh) * | 2012-09-17 | 2014-03-26 | 北京双鹭药业股份有限公司 | 一种高效制备重组人碱性成纤维细胞生长因子的方法 |
| US20140134673A1 (en) * | 2012-11-09 | 2014-05-15 | Gene-Vinate Limited | Means and methods for producing authentic human basic fibroblast growth factor |
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| US5859208A (en) * | 1988-07-06 | 1999-01-12 | Fiddes; John C. | Human basic fibroblast growth factor analog |
| KR100484653B1 (ko) * | 2004-05-06 | 2005-04-20 | 주식회사 대웅 | 원핵세포에서 활성형의 가용성 단백질을 제조하는 방법 및 이를 위한 폴리시스트론 벡터 |
| ES2399031T3 (es) | 2005-04-26 | 2013-03-25 | Sandoz Ag | Producción de proteínas recombinantes mediante escisión autoproteolítica de una proteína de fusión |
| CN102585010A (zh) | 2011-01-16 | 2012-07-18 | 董贵俊 | 一种检测重组人碱性成纤维细胞生长因子(rhbFGF)的免疫胶乳微球及其制备方法 |
| TWI643953B (zh) | 2014-12-11 | 2018-12-11 | 訊聯生物科技股份有限公司 | 以自體血漿培養原始細胞的方法 |
| EP3916085A1 (en) | 2014-12-30 | 2021-12-01 | Cell Cure Neurosciences Ltd. | Assessing retinal pigment epithelial cell populations |
-
2017
- 2017-06-23 WO PCT/CN2017/089810 patent/WO2018232745A1/zh unknown
- 2017-06-23 KR KR1020207002244A patent/KR102428209B1/ko active IP Right Grant
- 2017-06-23 EP EP17915171.7A patent/EP3643781A4/en active Pending
- 2017-06-23 US US16/625,191 patent/US11248032B2/en active Active
- 2017-06-23 CN CN201780092424.7A patent/CN110945123B/zh active Active
- 2017-06-23 SG SG11201912790WA patent/SG11201912790WA/en unknown
- 2017-06-23 JP JP2020520690A patent/JP7098724B2/ja active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003189865A (ja) * | 2001-12-26 | 2003-07-08 | Fuji Photo Film Co Ltd | 繊維芽細胞成長因子をコードする組み換えベクター |
| CN1448510A (zh) * | 2002-04-04 | 2003-10-15 | 北京三元基因工程有限公司 | 一种重组人碱性成纤维细胞生长因子的高效表达 |
| CN1733294A (zh) * | 2005-08-10 | 2006-02-15 | 南海朗肽制药有限公司 | 一种重组人碱性成纤维细胞生长因子凝胶剂及其制备方法 |
| CN102688479A (zh) * | 2012-06-20 | 2012-09-26 | 涂桂洪 | 预防干眼症的组合物、包括其的眼贴膜及该眼贴膜的制备方法 |
| CN103667329A (zh) * | 2012-09-17 | 2014-03-26 | 北京双鹭药业股份有限公司 | 一种高效制备重组人碱性成纤维细胞生长因子的方法 |
| US20140134673A1 (en) * | 2012-11-09 | 2014-05-15 | Gene-Vinate Limited | Means and methods for producing authentic human basic fibroblast growth factor |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115975002A (zh) * | 2022-08-16 | 2023-04-18 | 广东普罗凯融生物医药科技有限公司 | 一种重组人碱性成纤维细胞生长因子及其制备方法与应用 |
| CN115975002B (zh) * | 2022-08-16 | 2023-09-22 | 广东普罗凯融生物医药科技有限公司 | 一种重组人碱性成纤维细胞生长因子及其制备方法与应用 |
| CN116889545A (zh) * | 2023-06-27 | 2023-10-17 | 上海腾瑞制药股份有限公司 | 一种重组人酸性成纤维细胞生长因子凝胶剂及其制备工艺 |
| CN116889545B (zh) * | 2023-06-27 | 2023-12-29 | 上海腾瑞制药股份有限公司 | 一种重组人酸性成纤维细胞生长因子凝胶剂及其制备工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20200140509A1 (en) | 2020-05-07 |
| EP3643781A1 (en) | 2020-04-29 |
| SG11201912790WA (en) | 2020-01-30 |
| EP3643781A4 (en) | 2021-07-14 |
| US11248032B2 (en) | 2022-02-15 |
| CN110945123B (zh) | 2023-06-23 |
| JP2020533014A (ja) | 2020-11-19 |
| WO2018232745A1 (zh) | 2018-12-27 |
| JP7098724B2 (ja) | 2022-07-11 |
| KR102428209B1 (ko) | 2022-08-02 |
| KR20200020900A (ko) | 2020-02-26 |
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