CN110917056A - Toner with anti-wrinkle, moisturizing and whitening effects - Google Patents
Toner with anti-wrinkle, moisturizing and whitening effects Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
This scheme relates to cosmetics technical field. More particularly, the scheme relates to toner with anti-wrinkle, moisturizing and whitening effects. The toner comprises, by weight, 3-5% of alantolactone, 1-2% of caragana microphylla leaf extract and 1-3% of pine needle extract. The toner disclosed by the invention can realize a good whitening effect by specifically inhibiting the mechanism that tyrosinase blocks melanin generation. Meanwhile, the toner has a good antioxidant repair function, and the whitening effect of the toner is coordinately enhanced through the mutual promotion effect among the natural extracts in the components, so that the product has the effects of whitening, moisturizing, resisting aging, resisting wrinkles, fading color spots and the like. Meanwhile, the skin quality can be rapidly improved, the skin elasticity can be improved, wrinkles can be smoothed, and the like.
Description
Technical Field
This scheme relates to cosmetics technical field. More particularly, the scheme relates to toner with anti-wrinkle, moisturizing and whitening effects.
Background
The skin is one of the important organs of the human body and is an important mark for the health and beauty of the human body, and the face is the main skin part exposed outside and becomes the most main window for showing the skin quality. With the development of society and the progress of science and technology, the pressure of people on work and life is greater and greater, and the problem of environmental pollution is more and more serious. The long-term life of the skin care product in the environment with fast pace, irregular diet and great pollution causes the continuous weakening of the skin tolerance of people, the sensitive and damaged skin conditions are more and more serious, and more people have sub-health skin. Therefore, skin care has gradually become an indispensable part of human life.
Meanwhile, whitening is one of the effects pursued by women, and in common words, the whitening effect is one of the effects pursued by women, and with the development of the times, more and more women pay more attention to the whitening of the face. Then, the types of whitening products in the current market are more, but the products are different, and the components with important metal exceeding, chemical skin changing and even banning exist, so that the whitening products cause great harm to human bodies after long-term use and seriously damage the skin; in addition, the current product has single efficacy and only can whiten by inhibiting the activity of tyrosinase. Thus, there is a need in the market for more fully functional products.
Disclosure of Invention
The scheme aims to solve the problems of the existing whitening products, and provides the toner with the effects of resisting wrinkles, preserving moisture and whitening in order to develop a new product.
The technical scheme adopted by the scheme for solving the technical problem is as follows: a toner with anti-wrinkle, moisturizing and whitening effects comprises, by weight, 3-5% of alantolactone, 1-2% of caragana microphylla leaf extract and 1-3% of pine needle extract.
According to the invention, the alantolactone, the caragana microphylla leaf extract, the pine needle extract and the myricetin are combined for the skin whitening product for the first time, and the synergistic effect of the components enables the composition to have the effects of whitening, anti-aging and anti-freckle. The alantolactone is the main active component of the Tibetan radix aucklandiae, has obvious anti-inflammatory and liver protection activities, can inhibit the infection of human type mycobacterium tuberculosis, and can remove active oxygen free radicals; the pine needle extract is extracted from pine needle leaves, contains chemical book active ingredients such as lignans, volatile oils, crude proteins, amino acids, pigments, vitamins, polyphenols, fatty acids, flavones, glycosides and terpenes, has wide pharmacological action and pharmacological action on the aspects of aging resistance and the like, and the caragana microphylla leaf extract contains more flavonoids, anti-inflammatory and bacteriostatic components and whitening and freckle removing components. The components can regulate skin immunity from endogenous sources, enhance the self-repairing capability of the skin, and achieve the effects of whitening, moisturizing, relieving, anti-allergy, resisting inflammation, inhibiting bacteria and the like.
Preferably, the toner comprises 3.5% of alantolactone, 1.5% of caragana microphylla leaf extract and 2.5% of pine needle extract in percentage by weight.
Preferably, the toner also comprises 0.4 to 0.9 percent of sargassum fusiforme extract, 1.3 to 2.5 percent of mulberry leaf extract and 0.2 to 0.3 percent of ligustilide by weight percentage. The mulberry leaf extract has rich nutrition and has better auxiliary effect on the recovery of facial wound; the Cyrtymenia Sparsa extract mainly contains brown algae polyphenols, has strong antioxidant effect, and also has antitumor activity, antiviral activity, and deodorant activity. Ligustilide has anticholinergic, antioxidant and free radical scavenging effects, can effectively scavenge harmful free radicals, can be dissolved in matrix, and can be absorbed through skin.
Preferably, the toner further comprises 6-9% of polysaccharide compounds in percentage by weight.
Preferably, the polysaccharide compound comprises one or more of zymosan, polysaccharide SM-1, trehalose and oat glucan.
Preferably, the toner also comprises 15-18% of glycerol, 0.05-0.15% of aloe vera extract, 0.5-0.8% of ceramide, 0.1-0.2% of dipotassium glycyrrhizinate and 0.5-1.5% of sodium hyaluronate according to weight percentage.
Preferably, the caragana microphylla leaf extract is extracted by the following method: freeze drying Caragana Korshinskii kom leaves, pulverizing at 0-4 deg.C to below 100 mesh in a low temperature ultramicro pulverizer to obtain powder, mixing the powder with deionized 90% ethanol solution at a ratio of 1g powder to 8mL solution, adding sodium bicarbonate with a mass of 1.3% of the powder, heating to reflux and extracting for 1-3 times, filtering to remove impurities, and vacuum concentrating the filtrate under reduced pressure to obtain Caragana Korshinskii kom leaf extract.
A preparation method of a toner with anti-wrinkle, moisturizing and whitening effects comprises the following steps: adding water into a reaction container, heating to 80-85 deg.C, adding 15-18% of glycerol, 0.05-0.15% of Aloe barbadensis extract, 0.5-0.8% of ceramide, 0.1-0.2% of dipotassium glycyrrhizinate, and 0.5-1.5% of sodium hyaluronate, stirring uniformly until all components are dissolved, stirring continuously, and cooling to 40-45 deg.C; adding alantolactone 3-5%, caragana microphylla leaf extract 1-2%, and folium Pini extract 1-3%, stirring, adding Cyrtymenia Sparsa extract 0.4-0.9%, folium Mori extract 1.3-2.5%, and ligustilide 0.2-0.3%, stirring, and cooling to room temperature.
The beneficial effect of this scheme is: the toner disclosed by the invention can realize a good whitening effect by specifically inhibiting the mechanism that tyrosinase blocks melanin generation. Meanwhile, the toner has a good antioxidant repair function, and the whitening effect of the toner is coordinately enhanced through the mutual promotion effect among the natural extracts in the components, so that the product has the effects of whitening, moisturizing, resisting aging, resisting wrinkles, fading color spots and the like. Meanwhile, the skin quality can be rapidly improved, the skin elasticity can be improved, wrinkles can be smoothed, and the like.
Detailed Description
The technical solution of the present invention will be further specifically described below by way of specific examples. In the present invention, the raw materials and equipment used are commercially available or commonly used in the art, unless otherwise specified. The methods in the following examples are conventional in the art unless otherwise specified.
Example 1: a toner with anti-wrinkle, moisturizing and whitening effects comprises, by weight, 3% of alantolactone, 2% of caragana microphylla leaf extract, 1% of pine needle extract, 9% of polysaccharide compound (oat glucan), 15% of glycerol, 0.05% of aloe barbadensis extract, 0.8% of ceramide, 0.1% of dipotassium glycyrrhizinate, 1.5% of sodium hyaluronate and the balance of water.
Example 2: a toner with anti-wrinkle, moisturizing and whitening effects comprises, by weight, 3.5% of alantolactone, 1.5% of caragana microphylla leaf extract, 2.5% of pine needle extract, 6% of polysaccharide compound (oat glucan), 15% of glycerin, 0.15% of aloe barbadensis extract, 0.5% of ceramide, 0.2% of dipotassium glycyrrhizinate, 0.5% of sodium hyaluronate and the balance of water.
Example 3: on the basis of example 1, 0.4% of sargassum fusiforme extract, 1.8% of mulberry leaf extract and 0.2% of ligustilide are added, and the balance of water is added.
Example 4: on the basis of example 2, 0.6% of sargassum fusiforme extract, 2.5% of mulberry leaf extract and 0.3% of ligustilide are added, and the balance of water is added.
The extraction method of the caragana microphylla leaf extract used in the invention comprises the following steps: freeze drying Caragana Korshinskii kom leaves, pulverizing at 0-4 deg.C to below 100 mesh in a low temperature ultramicro pulverizer to obtain powder, mixing the powder with deionized 90% ethanol solution at a ratio of 1g powder to 8mL solution, adding sodium bicarbonate with a mass of 1.3% of the powder, heating to reflux and extracting for 1-3 times, filtering to remove impurities, and vacuum concentrating the filtrate under reduced pressure to obtain Caragana Korshinskii kom leaf extract.
The preparation method of the whitening toner comprises the following steps: adding water into a reaction vessel, heating to 80-85 deg.C, adding glycerol, Aloe Barbadensis Miller extract, ceramide, dipotassium glycyrrhizinate, and sodium hyaluronate, stirring uniformly until each component is dissolved, stirring continuously, and cooling to 40-45 deg.C; adding alantolactone, caragana microphylla leaf extract and pine needle extract, stirring well, adding Cyrtymenia Sparsa extract, folium Mori extract and ligustilide, stirring well, and cooling to room temperature.
The antioxidant activity of the essence is measured by DPPH method.
Accurately weighing DPPH reagent mg, dissolving with anhydrous ethanol, quantitatively transferring into 10mL volumetric flask, adding anhydrous ethanol to constant volume to scale, taking into volumetric flask, shaking to obtain DPPH stock solution with concentration of 0.1 mmol/L
Dissolving DPPH 1mg in about 20mL ethanol solvent, performing ultrasonic treatment for 5min, and shaking thoroughly and uniformly. 1mL of this DPPH solution was taken, and the value of A was measured at 519nm so that A became 1.2 to 1.3.
Adding 4.0mL of PPH solution and sample essence into a 10mL test tube in sequence, adding absolute ethyl alcohol to scale, immediately mixing, measuring a light absorption value (A) at a wavelength of 517nm by using a 1cm cuvette, marking the light absorption value as Ai, then measuring the light absorption value after storing in a greenhouse in a dark place for 30min, marking the light absorption value as Aj, and taking an ethanol solution only added with DPPH as a control test, and marking the light absorption value as Ac. The radical clearance (K) was calculated as follows:
K(%)=[1-(Ai-Aj)/Ac]*100%
the test was repeated three times, and the average was taken as the final result, and the results are shown in Table 1.
Determination of tyrosinase activity inhibiting ability:
3mL of 0.05% L-tyrosine, 4mL of phosphate buffer solution with pH 6.8 and 0.3 mL of sample solution are added into a 10mL centrifuge tube at a time, the mixture is shaken and heated in a water bath at 37 ℃ for 10min, 1mL of 500U/mL tyrosinase is added and heated for 5min, centrifugation is carried out (12000rpm, 5min), the absorbance A1 is measured at 475nm, and the absorbance A2 is measured when the phosphate buffer solution is used for replacing the sample solution. And calculating the inhibition rate of the sample solution on tyrosinase. The inhibition ratio of tyrosinase is (A2-A1)/A2, and the results are shown in Table 1.
Determination of the Activity of superoxide dismutase (SOD):
the experiment adopts a photochemical reduction method, and the principle is as follows: under the condition of the existence of methionine and riboflavin, the nitro blue tetrazole generates photochemical reduction reaction after being irradiated by light to generate blue methyl hydrazone, and the blue methyl hydrazone has maximum light absorption at 560 nm. SOD can inhibit photochemical reduction of NBT, and the inhibition intensity is in direct proportion to enzyme activity in a certain range.
Reagent:
1.50 mmol/l Phosphate Buffer (PBS) pH 7.8. Containing 0.1 mol/l EDTA.
2.220m mol/l methionine: 3.2824g methionine was weighed out and dissolved to 100ml (ready for use) in 50 mmol/l phosphate buffer pH 7.8.
3.1.25m mol/l Nitro-tetrazolium chloride (NBT) solution (ready-made): NBT (0.102 g) was weighed out and dissolved in 50 mmol/l Phosphate Buffer Solution (PBS) pH7.8 to 100 ml.
4.0.033m mol/l riboflavin: 2.52mg was weighed out and dissolved in PBS to a volume of 200ml (stored in a dark place).
The steps are carried out according to the conventional procedure of the method.
| Free radical clearance/%) | Tyrosinase inhibition% | Superoxide dismutase inhibition% | |
| Example 1 | 83.2 | 87.8 | 81.2 |
| Example 2 | 84.1 | 88.4 | 80.5 |
| Example 3 | 88.3 | 91.9 | 85.2 |
| Example 4 | 89.6 | 90.1 | 84.3 |
The result shows that the toner provided by the invention has remarkable free radical scavenging capacity and can effectively inhibit the activity of tyrosinase and the activity of superoxide dismutase. The toner disclosed by the invention can realize a good whitening effect by specifically inhibiting the mechanism that tyrosinase blocks melanin generation.
Skin whitening experiments.
Subject: 100 test subjects, which are female and have the age of 25-45 years, are selected, living habits are all kept overnight for a long time and face computers for a long time, facial skin with different degrees is dry, dark and dark, a random grouping principle is adopted, 25 subjects are selected for each group, and double-blind experiments are carried out according to examples 1-4. The test part is cheek, and the test time is 1 week, 2 weeks, 4 weeks and 6 weeks after the product to be tested is used. Subject skin data was collected and analyzed for changes in data before and after use for each test area and for differences between experimental and control groups. A skin tester (korean EHANG, EH-990U) for detecting moisture change and melanin change of the skin. The results are shown in the following table.
| Week 1 | Obvious moisture retention | Effective in keeping moisture | Ineffective moisture retention | Remarkable whitening effect | Effective in whitening skin | Ineffectiveness in whitening |
| Example 1 | 15 | 8 | 2 | 7 | 15 | 3 |
| Example 2 | 14 | 9 | 2 | 5 | 13 | 7 |
| Example 3 | 18 | 6 | 1 | 6 | 15 | 4 |
| Example 4 | 16 | 7 | 2 | 7 | 14 | 4 |
| Week 2 | Obvious moisture retention | Effective in keeping moisture | Ineffective moisture retention | Remarkable whitening effect | Effective in whitening skin | Ineffectiveness in whitening |
| Example 1 | 17 | 6 | 2 | 10 | 13 | 2 |
| Example 2 | 16 | 7 | 2 | 11 | 13 | 2 |
| Example 3 | 19 | 5 | 1 | 12 | 11 | 2 |
| Example 4 | 18 | 5 | 2 | 10 | 12 | 3 |
| Week 4 | Obvious moisture retention | Effective in keeping moisture | Ineffective moisture retention | Remarkable whitening effect | Effective in whitening skin | Ineffectiveness in whitening |
| Example 1 | 20 | 4 | 1 | 17 | 7 | 1 |
| Example 2 | 20 | 5 | 0 | 15 | 9 | 1 |
| Example 3 | 21 | 3 | 1 | 19 | 5 | 1 |
| Example 4 | 23 | 2 | 0 | 20 | 4 | 1 |
| Week 6 | Obvious moisture retention | Effective in keeping moisture | Ineffective moisture retention | Remarkable whitening effect | Effective in whitening skin | Ineffectiveness in whitening |
| Example 1 | 22 | 2 | 1 | 22 | 2 | 1 |
| Example 2 | 21 | 4 | 0 | 21 | 4 | 0 |
| Example 3 | 23 | 1 | 1 | 22 | 3 | 0 |
| Example 4 | 24 | 1 | 0 | 23 | 1 | 1 |
As can be seen from the above table, the whitening and moisturizing effect of the product of the present invention is generally better.
The above-described embodiments are only preferred embodiments of the present invention, and are not intended to limit the present invention in any way, and other variations and modifications may be made without departing from the spirit of the invention as set forth in the claims.
Claims (8)
1. A toner with anti-wrinkle, moisturizing and whitening effects is characterized in that: the toner comprises, by weight, 3-5% of alantolactone, 1-2% of caragana microphylla leaf extract and 1-3% of pine needle extract.
2. The toner with anti-wrinkle, moisturizing and whitening effects according to claim 1, which is characterized in that: the toner comprises, by weight, 3.5% of alantolactone, 1.5% of caragana microphylla leaf extract and 2.5% of pine needle extract.
3. The toner with anti-wrinkle, moisturizing and whitening effects according to claim 1, which is characterized in that: the toner also comprises 0.4-0.9% of sargassum fusiforme extract, 1.3-2.5% of mulberry leaf extract and 0.2-0.3% of ligustilide by weight percentage.
4. The toner with anti-wrinkle, moisturizing and whitening effects according to claim 1, which is characterized in that: the toner also comprises 6-9% of polysaccharide compounds according to weight percentage.
5. The toner with anti-wrinkle, moisturizing and whitening effects according to claim 4, characterized in that: the polysaccharide compound comprises one or more of zymosan, polysaccharide SM-1, trehalose, and oat glucan.
6. The toner with anti-wrinkle, moisturizing and whitening effects according to claim 1, which is characterized in that: the toner also comprises 15-18% of glycerol, 0.05-0.15% of aloe vera extract, 0.5-0.8% of ceramide, 0.1-0.2% of dipotassium glycyrrhizinate and 0.5-1.5% of sodium hyaluronate according to weight percentage.
7. The toner with anti-wrinkle, moisturizing and whitening effects according to claim 1, which is characterized in that: the extraction method of the caragana microphylla leaf extract comprises the following steps: freeze drying Caragana Korshinskii kom leaves, pulverizing at 0-4 deg.C to below 100 mesh in a low temperature ultramicro pulverizer to obtain powder, mixing the powder with deionized 90% ethanol solution at a ratio of 1g powder to 8mL solution, adding sodium bicarbonate with a mass of 1.3% of the powder, heating to reflux and extracting for 1-3 times, filtering to remove impurities, and vacuum concentrating the filtrate under reduced pressure to obtain Caragana Korshinskii kom leaf extract.
8. A preparation method of a toner with anti-wrinkle, moisturizing and whitening effects is characterized by comprising the following steps: the method comprises the following steps: adding water into a reaction container, heating to 80-85 deg.C, adding 15-18% of glycerol, 0.05-0.15% of Aloe barbadensis extract, 0.5-0.8% of ceramide, 0.1-0.2% of dipotassium glycyrrhizinate, and 0.5-1.5% of sodium hyaluronate, stirring uniformly until all components are dissolved, stirring continuously, and cooling to 40-45 deg.C; adding alantolactone 3-5%, caragana microphylla leaf extract 1-2%, and folium Pini extract 1-3%, stirring, adding Cyrtymenia Sparsa extract 0.4-0.9%, folium Mori extract 1.3-2.5%, and ligustilide 0.2-0.3%, stirring, and cooling to room temperature.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201911385717.1A CN110917056A (en) | 2019-12-29 | 2019-12-29 | Toner with anti-wrinkle, moisturizing and whitening effects |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201911385717.1A CN110917056A (en) | 2019-12-29 | 2019-12-29 | Toner with anti-wrinkle, moisturizing and whitening effects |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010083786A (en) * | 2008-09-30 | 2010-04-15 | Maruzen Pharmaceut Co Ltd | Anti-aging agent and skin cosmetic |
| CN105342914A (en) * | 2015-11-18 | 2016-02-24 | 关美玲 | Spot-removing whitening astringent toner and preparation method thereof |
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| CN107157829A (en) * | 2017-05-16 | 2017-09-15 | 佛山汇沐化学科技有限公司 | A kind of whitening itching-relieving hand frost |
| CN107397697A (en) * | 2017-08-30 | 2017-11-28 | 永安康健药业（武汉）有限公司 | A kind of whitening spot-eliminating composition and its application |
| CN109864912A (en) * | 2019-04-02 | 2019-06-11 | 云南菌沃生物技术有限公司 | A kind of natural pine needle skin repair Essence and its preparation process |
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2019
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010083786A (en) * | 2008-09-30 | 2010-04-15 | Maruzen Pharmaceut Co Ltd | Anti-aging agent and skin cosmetic |
| CN105342914A (en) * | 2015-11-18 | 2016-02-24 | 关美玲 | Spot-removing whitening astringent toner and preparation method thereof |
| CN105943459A (en) * | 2016-06-22 | 2016-09-21 | 安徽诚亚生物科技有限公司 | Traditional Chinese medicine toner |
| CN107157829A (en) * | 2017-05-16 | 2017-09-15 | 佛山汇沐化学科技有限公司 | A kind of whitening itching-relieving hand frost |
| CN107397697A (en) * | 2017-08-30 | 2017-11-28 | 永安康健药业（武汉）有限公司 | A kind of whitening spot-eliminating composition and its application |
| CN109864912A (en) * | 2019-04-02 | 2019-06-11 | 云南菌沃生物技术有限公司 | A kind of natural pine needle skin repair Essence and its preparation process |
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