CN112842960A - Cosmetic composition with ultraviolet resistance, whitening and aging resistance - Google Patents
Cosmetic composition with ultraviolet resistance, whitening and aging resistance Download PDFInfo
- Publication number
- CN112842960A CN112842960A CN202110151081.5A CN202110151081A CN112842960A CN 112842960 A CN112842960 A CN 112842960A CN 202110151081 A CN202110151081 A CN 202110151081A CN 112842960 A CN112842960 A CN 112842960A
- Authority
- CN
- China
- Prior art keywords
- whitening
- skin
- composition
- aging
- resisting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/591—Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596
Abstract
The invention relates to a cosmetic composition with ultraviolet resistance, whitening and aging resistance, which comprises the following components in percentage by mass: magnesium ascorbyl phosphate 20.0-80.0%, NMN 1.0-30.0%, green tea extract 0.1-10.0%, cubilose acid 20.0-80.0%, and Scutellariae radix extract 0.01-0.5%. The composition has high efficacy safety, can resist ultraviolet rays, whiten skin, prevent skin aging, reduce skin wrinkles, and keep the skin bright, bright and elastic.
Description
Technical Field
The invention relates to a cosmetic efficacy composition, in particular to a cosmetic composition with ultraviolet resistance, whitening and aging resistance.
Background
With the improvement of living standard of people, people pay more and more attention to the nursing and the maintenance of skin. Cosmetics are receiving more and more attention, and skin aging is a hot spot of current cosmetic industry attention. Two major important sources of skin aging are endogenous aging and exogenous aging. Endogenous aging occurs along with the increase of age, which is generally attributed to the change of telomere length and the accumulation of reactive oxygen species generated by long-term oxidative metabolism, so that the human body naturally ages at a relatively stable speed. The main reason for extrinsic skin aging is that the skin is often exposed to long-wave Ultraviolet (UVA) and medium-wave Ultraviolet (UVB) radiation in the sun, causing skin damage (e.g., erythema, oxidation, etc.) and aging. The most desirable method of combating extrinsic skin aging is to prevent damage to the skin by ultraviolet light in the sun, and repair the skin after damage.
At present, three ways of preventing ultraviolet rays from damaging skin mainly comprise physical sun protection, chemical sun protection and biological sun protection. The physical sun-screening principle is that inorganic particles such as titanium dioxide are added to reflect and scatter sunlight ultraviolet rays, so that the skin is protected from being damaged by the sunlight ultraviolet rays; the chemical sunscreen mainly comprises that an absorbent such as benzophenone is used for absorbing UVA and an absorbent such as salicylate is used for absorbing UVB; the biological sunscreen is prepared by adding natural Chinese herbal medicines, plant extracts, and antioxidant components with no toxic side effect or low toxic side effect into cosmetics, and if the components have the effects of resisting oxidation and free radicals, the sun protection index can be increased by adding the components. Meanwhile, compared with the added ingredients of physical and chemical sun protection, the skin care liquid is more beneficial to skin health.
Aging of skin caused by aging and erythema, pigmentation, skin aging caused by ultraviolet rays in sunlight all make it necessary to research a composition which can resist ultraviolet rays, whiten skin and resist aging.
Disclosure of Invention
The invention aims to provide a cosmetic composition with ultraviolet resistance, whitening and aging resistance, which can effectively enhance the ultraviolet resistance, whitening and aging resistance of cosmetics, is suitable for various people, is safe and nontoxic and has good use effect.
The technical problem to be solved by the invention is realized by the following technical scheme:
the composition with the functions of resisting ultraviolet rays, whitening skin and resisting aging simultaneously comprises the following components in percentage by mass: magnesium ascorbyl phosphate 20.0-80.0%, NMN 1.0-30.0%, green tea extract 0.1-10.0%, cubilose acid 20.0-80.0%, and Scutellariae radix extract 0.01-0.5%.
Preferably, the technical scheme comprises the following components in percentage by mass: 30.0-50.0% of magnesium ascorbyl phosphate, 5.0-20.0% of NMN, 1.0-5.0% of green tea extract, 30.0-50.0% of cubilose acid and 0.01-0.40% of scutellaria baicalensis root extract.
Preferably, the technical scheme comprises the following components in percentage by mass: magnesium ascorbyl phosphate 40.0%, NMN 10.0%, green tea extract 4.8%, cubilose acid 45.0%, and radix Scutellariae extract 0.2%.
Preferably, in the technical scheme, the magnesium ascorbyl phosphate is prepared by further reacting phosphorylated vitamin C with magnesium oxide and refining, and the content of effective substances is more than or equal to 95%; the NMN is obtained by enzymatic synthesis, and the content of active substances is more than or equal to 99 percent; the cubilose acid is prepared by crushing raw materials, extracting, filtering, concentrating, purifying, drying and crushing, and the content of effective substances is more than or equal to 98%.
Preferably, in the above technical solution, the green tea extract is obtained by the following steps: selecting green tea, deactivating enzyme, kneading, drying, pulverizing, extracting with water under reflux for 3 times, mixing extractive solutions, filtering, centrifuging to remove residue, concentrating, spray drying to obtain powder with effective component content of 98% or more;
preferably, in the above technical solution, the scutellaria root extract is obtained by the following steps: pulverizing dried raw materials, extracting with 70% ethanol under reflux for 3 times, mixing filtrates, concentrating under reduced pressure, extracting with isovolumetric petroleum ether for 3 times, extracting alcohol-soluble component with n-butanol, concentrating the alcohol layer, and concentrating under reduced pressure to obtain the final product with effective component content of not less than 90.0%.
A preparation method of a composition with ultraviolet resistance, whitening and aging resistance at the same time comprises the following steps:
(1) weighing various raw materials according to a formula ratio, and mixing the raw materials together;
(2) and (4) inspecting the mixture, filling, and taking out of a warehouse to serve as a cosmetic efficacy raw material for later use.
A cosmetic simultaneously containing anti-ultraviolet, whitening and anti-aging composition comprises 0.5-50.0% of the composition by mass and the balance of matrix.
Preferably, in the above technical scheme, the mass ratio of the composition in the cosmetic is 1.0-10.0%, and the balance is the matrix.
Preferably, in the above technical scheme, the cosmetic is a cream, a mask, an emulsion or an essence.
The inventor of the application finds that certain compound raw materials are added into the cosmetics in the long-term research and development process, and the effects of resisting ultraviolet rays, whitening and resisting aging can be achieved at the same time. The main reason is that the added components have one or more of ultraviolet resistance, whitening and anti-aging effects, and the added components are compounded together according to a certain proportion and added into cosmetics, so that the effects can be better exerted, the use is convenient, and various requirements can be met simultaneously.
The ascorbic acid magnesium phosphate, NMN, green tea extract, cubilose acid and scutellaria root extract are dry powder substances.
The magnesium ascorbyl phosphate is an internationally recognized water-soluble efficient freckle-removing whitening agent, can enable skin to become fine and smooth, increases the elasticity of the skin and enables the skin to be white. Simultaneously, the product can be used as antioxidant to eliminate oxygen free radical, thereby having wrinkle removing and antiaging effects.
NMN is an effective anti-aging raw material, has the effects of resisting oxidation and repairing skin barrier function, and thus effectively delays skin aging.
The green tea extract contains tea polyphenol which can inhibit lipid peroxidation and achieve the physiological effects of improving the stability of skin cell membranes and delaying the aging process by the action of scavenging free radicals. Meanwhile, the tea polyphenol compounds are sensitive to ultraviolet rays, and especially have strong absorption on the ultraviolet rays with the wavelength of 200-330 nm, so that the tea polyphenol compounds have the effect of resisting the ultraviolet rays.
The cubilose acid can penetrate into the skin basal layer, improve the cell activity, effectively repair the skin barrier, tighten and relax the skin and enable the skin to be smoother and more elastic.
The Scutellariae radix extract contains baicalin which can effectively absorb ultraviolet rays, remove oxygen free radicals, and inhibit melanin generation, and has effects of improving skin metabolism, skin elasticity and wrinkle resistance.
The technical scheme of the invention has the following technical effects:
1. the invention achieves the effects of ultraviolet resistance, whitening and aging resistance from various mechanisms by compounding various active ingredients together according to a certain proportion.
2. The invention has high safety as cosmetic raw materials.
3. The invention can be added into cosmetics in various dosage forms such as cream, facial mask, emulsion, essence and the like, and meets the requirements of different people.
Detailed Description
The following specific embodiments are provided to further illustrate the present invention, but the present invention is not limited to only the following embodiments.
The test methods used above and in the examples below are conventional methods unless otherwise specified. The materials, reagents and the like used in the above and following examples are commercially available unless otherwise specified.
Example 1
The composition simultaneously has the effects of resisting ultraviolet rays, whitening skin and resisting aging, comprises a plurality of effective components, and the effective components of the composition are compounded, wherein the detailed mixture ratio is shown in table 1.
TABLE 1 ingredient ratio table
The preparation method of the composition comprises the following steps:
mixing magnesium ascorbyl phosphate, NMN, green tea extract, nidus Collocaliae acid, and Scutellariae radix extract, and stirring to obtain composition with effects of resisting ultraviolet, whitening skin, and resisting aging.
Based on the composition prepared in example 1, the composition was further applied to cosmetics in various formulations. The following examples are described in detail.
Example 2
A preparation method of a face cream with the effects of resisting ultraviolet rays, whitening and resisting aging simultaneously comprises the following steps:
stirring and heating 0.3% carbomer, 0.1% disodium EDTA and required deionized water to 80 +/-2 ℃ to obtain a water phase; stirring and heating 8.0% caprylic/capric triglyceride, 3.0% isopropyl myristate, 5.0% argania spinosa kernel oil, 2% glyceryl stearate, 2.0% polysorbate-60, 0.8% sorbitan stearate, 3.0% cetostearyl alcohol, 2.0% PEG-100 stearate, 1.0% beeswax and 1.0% mineral wax to 80 +/-2 ℃ for dissolving to obtain an oil phase; adding the oil phase into the water phase, stirring for 10min, cooling to 45 deg.C, adding 5.0% magnesium ascorbyl phosphate, NMN, green tea extract, nidus Collocaliae acid, and Scutellariae radix extract composition, adding 0.1% triethanolamine, 0.5% phenoxyethanol, and 0.2% essence at 40 deg.C, stirring, and mixing to obtain the final product.
Example 3
A preparation method of a facial mask with ultraviolet resistance, whitening and anti-aging effects at the same time comprises the following steps:
mixing 0.1% of allantoin PCA sodium, 0.1% of EDTA disodium, 5.0% of 1, 3-butanediol, 8.0% of glycerol, 1.0% of betaine, 0.1% of xanthan gum, 0.1% of hydrolyzed sodium hyaluronate, 0.1% of hydroxyethyl cellulose and required deionized water, heating to 80 +/-2 ℃ to dissolve to obtain a water phase, cooling to 45 ℃, adding 5.0% of magnesium ascorbyl phosphate, NMN, green tea extract, cubilose acid and scutellaria baicalensis root extract composition, adding 0.5% of phenoxyethanol at 40 ℃, continuously stirring with 0.1% of essence, and uniformly mixing to obtain the functional facial mask.
Example 4
A preparation method of an emulsion with ultraviolet resistance, whitening and anti-aging effects at the same time comprises the following steps:
mixing 5.0% of glycerol, 0.1% of disodium EDTA and required deionized water, and heating to 80 +/-2 ℃ to obtain a water phase; mixing 6.0% caprylic triglyceride, 3.0% isopropyl myristate, 3.0% Aralia mandshurica kernel oil, 1.0% glyceryl stearate, 2.0% polysorbate-60, 0.8% sorbitan stearate, and 1.0% spermaceti stearate, heating to 80 + -2 deg.C, and dissolving to obtain oil phase; adding the oil phase into the water phase, mixing and stirring for 10min, cooling to 45 deg.C, adding 5.0% magnesium ascorbyl phosphate, NMN, green tea extract, nidus Collocaliae acid, and Scutellariae radix extract composition, adding 0.5% phenoxyethanol and 0.1% essence at 40 deg.C, stirring, and mixing to obtain the effective emulsion.
Example 5
The preparation method of the essence simultaneously having the effects of resisting ultraviolet rays, whitening skin and resisting aging comprises the following steps:
mixing 0.1% of allantoin PCA sodium, 0.1% of EDTA disodium, 3.0% of 1, 3-butanediol, 2.0% of glycerol, 1.0% of betaine, 0.1% of xanthan gum, 0.2% of hydrolyzed sodium hyaluronate and required deionized water uniformly, heating to 80 +/-2 ℃ for dissolving to obtain a water phase, starting cooling, adding 5.0% of magnesium ascorbyl phosphate, NMN, a green tea extract, bird's nest acid and a scutellaria root extract when the temperature is 45 ℃, adding 0.5% of phenoxyethanol and 0.1% of essence when the temperature is 40 ℃, continuously stirring, and mixing uniformly to obtain the effect essence liquid.
The effect of the present invention was verified by preparing an essence having uv-resistant, whitening, and anti-aging effects simultaneously according to the formula No. 5 of example 1 and the method of example 5 in the following table. The specific formulation is shown in Table 2.
TABLE 2
In order to determine the effect of the above example 5, comparative example 1 and comparative example 2 on the change of the skin surface and determine the improvement effect of the skin, the following relevant tests are required, and the detection method is as follows:
1. skin sensitization test in guinea pigs:
1.1. according to the skin allergy test method published in the technical Specification for cosmetic safety, 35 healthy guinea pigs were tested for skin sensitization by a topical closed skin application method. Test component 20 guinea pigs, the cosmetics provided in examples 1 to 5 of the present invention were implemented: a positive control component 10 guinea pigs, and a butanediol solution (volume fraction is 2/98) of 2, 4-dinitrochlorobenzene is used as a positive sensitizer; blank control component 5 guinea pigs.
1.2 induced contact test: on day 1, 0.2g of the prepared cosmetic in the above embodiment was applied to the depilated area of 2cm × 2cm on the back of the left side of the subject guinea pig, covered with 2 layers of gauze and 1 layer of cellophane, and sealed with a non-irritating adhesive tape for 6 hours. The same procedure was repeated on day 7 and day 14. The blank control group was not subjected to the contact induction test, and the positive control group was subjected to the positive control for the left-side depilated area of the back, and the contact induction method was the same as above.
1.3 stimulated contact test: the challenge contact test was performed on day 28, and the right depilated area of the guinea pig was treated in the same manner as the challenge contact, and the test substance was removed after 6 hours, immediately observed, and then the skin allergy was observed again at 24 and 48/72 hours. Application of the cosmetic positive control prepared in the specific examples of this patent to the right depilatory area of the blank control the application of the positive control to the right depilatory area of the positive control was performed as described above for the stimulation contact method.
1.4 results of skin sensitization test on guinea pigs:
as a general case, the change in weight of the guinea pigs, compared with the blank control group, can be seen that the use of the cosmetic prepared in this example did not cause the weight of the guinea pigs to decrease but slightly increased during both the induction contact and challenge contact tests; the positive control group of guinea pigs had a significant weight loss.
With regard to the test phenomena of cutaneous allergies and sensitization intensity, the positive sensitizer 2, 4-dinitrochlorobenzene itself acts as a very strong sensitizer, and all guinea pigs of the positive control group have developed erythema and edema during the induction of contact; within three days after the contact stimulation test, the phenomena of erythema and edema are more obvious, and the skin reaction is moderate; meanwhile, the sensitization rate reaches extremely strong strength. While the guinea pigs of the test group using the cosmetic of this patent and the placebo group did not find erythema and edema during and within three days after the induction and challenge contacts; indicating no skin allergy and no sensitization in guinea pigs.
The test shows that the cosmetics prepared in the embodiment and the comparative example are safe daily cosmetics.
2. And (3) testing the ultraviolet resistance effect:
two indexes for evaluating the ultraviolet resistance effect of the cosmetics are a Sun Protection Factor (SPF) value and a PFA value respectively.
The SPF value is the ratio of the MED (minimum erythema dose) required to cause erythema on the skin protected with the sunscreen cosmetic to the MED required to cause erythema on the skin not protected, and the greater the SPF value, the better the uv protection effect.
The PFA value is a ratio of MPPD (minimum amount of permanent blackening) required to cause blackening of skin protected by sunscreen cosmetics to MPPD required to cause blackening of skin not protected, and the larger the PFA value, the better the ultraviolet protection effect.
Measured according to the test method published in technical Specification for cosmetic safety. 10 volunteers between the ages of 25 and 60 were selected. The cosmetics prepared in the embodiment 5 are applied on the skin of the tested part of each subject according to requirements, and are irradiated by an artificial light source according to requirements after 15-30min, and the SPF value and the PFA value are calculated by the following formulas. The SPF value is the MED of the sample for protecting skin/the MED of the sample without protecting skin, and the larger the SPF value is, the better the protection effect is. PFA is MPPD for protecting skin/MPPD for protecting skin of a test product, and the larger the PFA value is, the better the effect is. The results are shown in Table 3.
Table 3 test result table of sun protection value
| Example 5 | Comparative example 1 | Comparative example 2 | |
| SPF value | 50.2 | 20.0 | 15.0 |
| PFA value | 18.5 | 9.7 | 8.6 |
3. And (3) testing the whitening effect:
two indexes for evaluating the whitening effect of the cosmetics are a skin chromaticity L value and a skin melanin value respectively.
The L value of the skin color is measured by using a Minolta chromameter CD7000, the skin melanin value is measured by a German CK Mexameter MX18, and the whitening effect of the product is comprehensively evaluated according to the L value of the skin color and the change condition of the skin melanin value.
20 volunteers between the ages of 25 and 60 were selected. Before the test is started, the skin of the arm of each subject is detected, and the skin chromaticity L value and the skin melanin value are recorded. Each subject was applied with the cosmetic prepared in this example 5 once in the morning and once in the evening. During the period, except for normal cleaning, other cosmetics are prohibited. After two months of testing, the arm skin of each subject was again examined and the skin chroma L value and skin melanin value were recorded. The whitening degree of the skin is calculated by using the following formula: the increase rate of the skin color L value and the decrease rate of the skin melanin value (post-test value-pre-test value)/pre-test value × 100%. The larger the increase rate of the L value of the skin chromaticity is, the higher the decrease rate of the melanin value of the skin is, and the better the whitening effect is. The results are shown in Table 4.
Table 4 test results of whitening effect table
| Example 5 | Comparative example 1 | Comparative example 2 | |
| L value increase of skin color% | 61.2 | 50.4 | 45.2 |
| The reduction rate of skin melanin value reaches% | 22.8 | 11.7 | 12.3 |
4. Anti-aging Effect test
Two important indicators for evaluating the anti-aging effect of cosmetics are the change in skin roughness and skin elasticity.
The Korean fourth-generation intelligent magic mirror instrument is used, the five-spectrum imaging technology is used, and after data are collected, the corresponding skin roughness index numerical value is directly obtained through the cloud computing technology. The skin of the aged of 88 years is 0%, and the higher the value is, the more delicate the skin is.
The change in the elasticity value of the facial skin of the subject was measured by a German CK skin elasticity tester (MPA 580). Higher values indicate better skin elasticity.
20 volunteers between the ages of 25 and 60 were selected. Before the test is started, the skin of each subject is tested, and the values of the skin roughness index and the skin elasticity index are recorded. Each subject was applied with the cosmetics prepared in this example once in the morning and once in the evening. In addition to cleansing, other cosmetics are used for tightening the skin. After two months of testing, the skin of each subject was again examined and the values of skin roughness index and skin elasticity index were recorded. The skin aging resistance was calculated using the following formula: skin roughness index and elasticity index rise rate ═ (post-test value-pre-test value)/pre-test value × 100%. The greater the rate of rise, the better the anti-aging effect. The results are shown in Table 5.
TABLE 5 anti-aging Effect test results Table
| Example 5 | Comparative example 1 | Comparative example 2 | |
| Increase in skin roughness index% | 40 | 30 | 25 |
| Rate of increase in skin elasticity index% | 30 | 22 | 18 |
The test results show that the efficacy composition is a safe and excellent composition with ultraviolet resistance, whitening and aging resistance.
The composition with the ultraviolet-resistant, whitening and anti-aging effects is safe and effective, can be added into cosmetics in various dosage forms such as cream, facial mask, emulsion, essence and the like, can effectively enhance the ultraviolet-resistant, whitening and anti-aging effects of the cosmetics through tests, is safe and non-toxic, and is an ideal ultraviolet-resistant, whitening and anti-aging cosmetic effect raw material.
Although the present invention has been described with reference to the above embodiments, it should be understood that the present invention is not limited thereto, and various changes and modifications may be made by those skilled in the art without departing from the spirit and scope of the present invention.
Claims (10)
1. The composition with the functions of resisting ultraviolet rays, whitening skin and resisting aging is characterized by comprising the following components in percentage by mass: magnesium ascorbyl phosphate 20.0-80.0%, NMN 1.0-30.0%, green tea extract 0.1-10.0%, cubilose acid 20.0-80.0%, and Scutellariae radix extract 0.01-0.5%.
2. The composition with the functions of resisting ultraviolet rays, whitening and resisting aging as claimed in claim 1, is characterized by comprising the following components in percentage by mass: 30.0-50.0% of magnesium ascorbyl phosphate, 5.0-20.0% of NMN, 1.0-5.0% of green tea extract, 30.0-50.0% of cubilose acid and 0.01-0.40% of scutellaria baicalensis root extract.
3. The composition with the functions of resisting ultraviolet rays, whitening and resisting aging as claimed in claim 2, is characterized by comprising the following components in percentage by mass: magnesium ascorbyl phosphate 40.0%, NMN 10.0%, green tea extract 4.8%, cubilose acid 45.0%, and radix Scutellariae extract 0.2%.
4. The composition with ultraviolet resistance, whitening and aging resistance as claimed in claims 1-3, wherein the magnesium ascorbyl phosphate is prepared by further reacting with magnesium oxide after vitamin C is phosphorylated, and the content of active substances is more than or equal to 95%; the NMN is obtained by enzymatic synthesis, and the content of active substances is more than or equal to 99 percent; the cubilose acid is prepared by crushing raw materials, extracting, filtering, concentrating, purifying, drying and crushing, and the content of effective substances is more than or equal to 98%.
5. The composition with the functions of resisting ultraviolet rays, whitening and resisting aging as claimed in claims 1 to 3, wherein the green tea extract is obtained by the following steps: selecting green tea, deactivating enzyme, kneading, drying, pulverizing, extracting with water under reflux for 3 times, mixing extractive solutions, filtering, centrifuging to remove residue, concentrating, spraying powder, and drying to obtain the final product with effective component content of 98% or more.
6. The composition with the effects of resisting ultraviolet rays, whitening and resisting aging as claimed in claims 1 to 3, wherein the scutellaria baicalensis root extract is obtained by the following steps: pulverizing dried raw materials, extracting with 70% ethanol under reflux for 3 times, mixing filtrates, concentrating under reduced pressure, extracting with isovolumetric petroleum ether for 3 times, extracting alcohol-soluble component with n-butanol, concentrating the alcohol layer, and concentrating under reduced pressure to obtain the final product with effective component content of not less than 90.0%.
7. The preparation method of the composition with ultraviolet resistance, whitening and aging resistance as claimed in claims 1-6 is characterized by comprising the following steps:
(1) weighing various raw materials according to a formula ratio, and mixing the raw materials together;
(2) and (4) inspecting the mixture, filling, and taking out of a warehouse to serve as a cosmetic efficacy raw material for later use.
8. The cosmetic containing the composition with the functions of resisting ultraviolet rays, whitening and resisting aging as claimed in any one of claims 1 to 3, is characterized in that the composition accounts for 0.5 to 50.0 percent by mass of the cosmetic, and the balance is matrix.
9. The cosmetic according to claim 8, wherein the composition is contained in the cosmetic in a mass ratio of 1.0 to 10.0%, and the balance is a base.
10. The cosmetic according to claim 8, wherein the cosmetic is a cream, a pack, a lotion or a serum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110151081.5A CN112842960A (en) | 2021-02-03 | 2021-02-03 | Cosmetic composition with ultraviolet resistance, whitening and aging resistance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110151081.5A CN112842960A (en) | 2021-02-03 | 2021-02-03 | Cosmetic composition with ultraviolet resistance, whitening and aging resistance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112842960A true CN112842960A (en) | 2021-05-28 |
Family
ID=75986456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110151081.5A Pending CN112842960A (en) | 2021-02-03 | 2021-02-03 | Cosmetic composition with ultraviolet resistance, whitening and aging resistance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112842960A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876639A (en) * | 2021-11-12 | 2022-01-04 | 湖北省麦诗特生物科技有限公司 | A facial cream composition containing liposome for improving skin elasticity and its preparation method |
| CN113876681A (en) * | 2021-11-12 | 2022-01-04 | 湖北省麦诗特生物科技有限公司 | Face cream composition with effect of improving skin glossiness and preparation method and application thereof |
| CN114557931A (en) * | 2021-12-01 | 2022-05-31 | 上海自易品牌管理有限公司 | Whitening, moisturizing and anti-saccharification composition, preparation method and application thereof |
| CN114748379A (en) * | 2022-05-05 | 2022-07-15 | 有货(北京)信息技术有限公司 | NMN-containing pure crystalline amino acid facial cleanser and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104771330A (en) * | 2015-03-16 | 2015-07-15 | 邦泰生物工程(深圳)有限公司 | Cosmetic anti-aging skincare composition containing nicotinamide mononucleotide (NMN) |
| KR20160047914A (en) * | 2014-10-23 | 2016-05-03 | 주식회사 엘지생활건강 | Anti-aging cosmetic composition comprising precursor of Nicotinamide adenine dinucleotide |
| JP6352825B2 (en) * | 2015-01-23 | 2018-07-04 | 株式会社ベスビオ | Cosmetics |
| CN109350557A (en) * | 2018-05-25 | 2019-02-19 | 泓博元生命科技（深圳）有限公司 | Anti-apolexis composition, skin care item comprising NADH and ceramide and the preparation method and application thereof |
| CN110859772A (en) * | 2019-11-08 | 2020-03-06 | 泉后(广州)生物科技研究院有限公司 | Composition with seven whitening effects and preparation method and application thereof |
| CN111920735A (en) * | 2020-08-21 | 2020-11-13 | 广东盛普生命科技有限公司 | Plant-derived anti-aging composition and application thereof |
-
2021
- 2021-02-03 CN CN202110151081.5A patent/CN112842960A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160047914A (en) * | 2014-10-23 | 2016-05-03 | 주식회사 엘지생활건강 | Anti-aging cosmetic composition comprising precursor of Nicotinamide adenine dinucleotide |
| JP6352825B2 (en) * | 2015-01-23 | 2018-07-04 | 株式会社ベスビオ | Cosmetics |
| CN104771330A (en) * | 2015-03-16 | 2015-07-15 | 邦泰生物工程(深圳)有限公司 | Cosmetic anti-aging skincare composition containing nicotinamide mononucleotide (NMN) |
| CN109350557A (en) * | 2018-05-25 | 2019-02-19 | 泓博元生命科技（深圳）有限公司 | Anti-apolexis composition, skin care item comprising NADH and ceramide and the preparation method and application thereof |
| CN110859772A (en) * | 2019-11-08 | 2020-03-06 | 泉后(广州)生物科技研究院有限公司 | Composition with seven whitening effects and preparation method and application thereof |
| CN111920735A (en) * | 2020-08-21 | 2020-11-13 | 广东盛普生命科技有限公司 | Plant-derived anti-aging composition and application thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876639A (en) * | 2021-11-12 | 2022-01-04 | 湖北省麦诗特生物科技有限公司 | A facial cream composition containing liposome for improving skin elasticity and its preparation method |
| CN113876681A (en) * | 2021-11-12 | 2022-01-04 | 湖北省麦诗特生物科技有限公司 | Face cream composition with effect of improving skin glossiness and preparation method and application thereof |
| CN113876639B (en) * | 2021-11-12 | 2023-08-22 | 湖北省麦诗特生物科技有限公司 | A facial cream composition containing liposome for improving skin elasticity, and its preparation method |
| CN113876681B (en) * | 2021-11-12 | 2024-01-26 | 湖北省麦诗特生物科技有限公司 | Face cream composition with effect of improving skin glossiness and preparation method and application thereof |
| CN114557931A (en) * | 2021-12-01 | 2022-05-31 | 上海自易品牌管理有限公司 | Whitening, moisturizing and anti-saccharification composition, preparation method and application thereof |
| CN114748379A (en) * | 2022-05-05 | 2022-07-15 | 有货(北京)信息技术有限公司 | NMN-containing pure crystalline amino acid facial cleanser and preparation method thereof |
| CN114748379B (en) * | 2022-05-05 | 2023-10-24 | 有货(北京)信息技术有限公司 | Pure crystal type amino acid facial cleanser containing NMN and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112842960A (en) | Cosmetic composition with ultraviolet resistance, whitening and aging resistance | |
| US20180353424A1 (en) | Camellia extract, its preparation method, and its use | |
| CN106176259B (en) | Sunscreen cream with double isolation and after-sun repair effects | |
| CN110339076B (en) | Sun-screening composition with broad-spectrum light protection effect and preparation method and application thereof | |
| CN111700811B (en) | Whitening and sunscreen dual-function sunscreen spray and preparation method thereof | |
| CN112494406A (en) | Whitening and freckle-removing cosmetic and preparation method thereof | |
| CN108578325A (en) | Moisturizing and sun-screening composition and application thereof | |
| CN113041172B (en) | Sebum membrane bionic composition for skin barrier repair, application thereof and cosmetics | |
| EP1648391A1 (en) | Method and preparation for reducing sunburn cell formation in skin | |
| KR101639578B1 (en) | Cosmetic composition containing Ocimum basilicum seed extract | |
| CN108969407A (en) | Sun-proof essence cream and preparation method thereof | |
| KR19990086516A (en) | Anti-aging cosmetic composition containing ginseng extract | |
| KR101056756B1 (en) | Cosmetic composition containing herb medicine extracts | |
| CN111297733A (en) | Paeonol-containing high-moisture-retention sun-screening agent and preparation method thereof | |
| CN109453088B (en) | Whitening and firming cream, preparation method thereof and tyrosinase inhibitor | |
| CN111150673A (en) | Anti-ultraviolet and anti-blue-light composition and application thereof | |
| CN103006477A (en) | Camellia oil emollient cream | |
| KR20090002369A (en) | Cosmetic composition with the antioxidant effect protecting skins aging | |
| CN110638686B (en) | Skin care composition with effects of inhibiting color spots and resisting skin photoaging and application thereof | |
| CN115487131A (en) | Daily facial skin care composition and preparation method thereof | |
| KR20090092898A (en) | Cosmetic composition containing korean natural medical-herbal extracts with the whitening and antioxidant effect | |
| CN110496086B (en) | Cool and refreshing sun-proof air cushion containing dendrobium officinale extract and preparation method thereof | |
| CN111658599A (en) | Liposome sunscreen cosmetic and preparation method thereof | |
| WO2015078398A1 (en) | Chinese herbal medicine compound for repairing ultraviolet damage, and uses thereof in cosmetics | |
| KR20110063912A (en) | A topical composition comprising the extract of platycodi radix, bupleuri radix and ginseng radix and the purified fractions therefrom inhibiting skin aging and wrinkle formation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: 11F-1, 11th Floor, Block B, No. 3 Shilibaojia, Chaoyang District, Beijing 100025 Applicant after: Beijing Jianxun Pharmaceutical Technology Co.,Ltd. Address before: 100124 1215, block a, Jinhai business center, Baiziwan, Chaoyang District, Beijing Applicant before: Beijing Jianxun Pharmaceutical Technology Co.,Ltd. |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210528 |