CN110785082B - 包含三芳基聚胺的组合物和方法 - Google Patents
包含三芳基聚胺的组合物和方法 Download PDFInfo
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- CN110785082B CN110785082B CN201880037491.3A CN201880037491A CN110785082B CN 110785082 B CN110785082 B CN 110785082B CN 201880037491 A CN201880037491 A CN 201880037491A CN 110785082 B CN110785082 B CN 110785082B
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762482106P | 2017-04-05 | 2017-04-05 | |
| US62/482,106 | 2017-04-05 | ||
| PCT/US2018/026320 WO2018187615A1 (en) | 2017-04-05 | 2018-04-05 | Compositions and methods comprising a triaryl polyamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110785082A CN110785082A (zh) | 2020-02-11 |
| CN110785082B true CN110785082B (zh) | 2021-12-28 |
Family
ID=62067821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880037491.3A Active CN110785082B (zh) | 2017-04-05 | 2018-04-05 | 包含三芳基聚胺的组合物和方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11352315B2 (enExample) |
| EP (1) | EP3606344B1 (enExample) |
| JP (1) | JP7041166B2 (enExample) |
| CN (1) | CN110785082B (enExample) |
| AU (1) | AU2018249550B2 (enExample) |
| CA (1) | CA3058813A1 (enExample) |
| WO (1) | WO2018187615A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0811530B1 (pt) | 2007-05-14 | 2019-01-02 | Research Foundation Of State Univ Of New York | composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| HK1255383A1 (zh) | 2015-07-31 | 2019-08-16 | The Research Institute At Nationwide Children's Hospital | 去除生物膜的肽及抗體 |
| EP3365027B1 (en) | 2015-10-14 | 2022-03-30 | Research Institute at Nationwide Children's Hospital | Hu specific antibodies and their use in inhibiting biofilm |
| AU2018249550B2 (en) | 2017-04-05 | 2023-11-30 | Curza, Inc. | Compositions and methods comprising a triaryl polyamine |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| WO2020006528A2 (en) * | 2018-06-29 | 2020-01-02 | Research Institute At Nationwide Children's Hospital | Compositions and methods for mediating eps |
| MX2021003838A (es) | 2018-10-05 | 2021-05-27 | Res Inst Nationwide Childrens Hospital | Derivados de proteina hmgb1 para la eliminacion de biopeliculas. |
| WO2021207247A1 (en) * | 2020-04-07 | 2021-10-14 | Kalin Health Llc | Spermidine-supplemented food products |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004030672A1 (en) * | 2002-10-02 | 2004-04-15 | Merck Patent Gmbh | Use of 4 amino-quinazolines as anti cancer agents |
| WO2012151554A1 (en) * | 2011-05-04 | 2012-11-08 | President And Fellows Of Harvard College | Polyamines for treating biofilms |
| CN105407729A (zh) * | 2013-05-22 | 2016-03-16 | 库扎环球有限责任公司 | 包含聚胺的组合物和方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4038312A (en) | 1975-08-22 | 1977-07-26 | E. I. Du Pont De Nemours And Company | Tricyclic phosphorous triamides |
| US4340756A (en) | 1981-02-04 | 1982-07-20 | Merck & Co., Inc. | Polyamine compounds as antibacterial agents |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4505861A (en) | 1982-07-23 | 1985-03-19 | University Of Florida | Methods and intermediates for the preparation of spermidine, homospermidine and norspermidine |
| US5316757A (en) | 1984-10-18 | 1994-05-31 | Board Of Regents, The University Of Texas System | Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups |
| HUT74005A (en) | 1993-02-23 | 1996-10-28 | Merrell Pharma Inc | Polyamine derivatives as radioprotective agents and pharmaceutical compositions containing them |
| US5583239A (en) | 1995-05-30 | 1996-12-10 | Lehigh University | Antimicrobial sterol conjugates |
| EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| US6077954A (en) | 1996-08-01 | 2000-06-20 | Isis Pharmaceuticals, Inc. | Substituted heterocyclic compounds |
| US7425579B2 (en) | 1998-04-21 | 2008-09-16 | Universite Laval | Methods for inhibiting activity of polyamine transporters |
| US6149822A (en) | 1999-03-01 | 2000-11-21 | Polymer Ventures, Inc. | Bio-film control |
| US6395189B1 (en) | 1999-03-01 | 2002-05-28 | Polymer Ventures, Inc. | Method for the control of biofilms |
| PL354994A1 (en) | 1999-10-26 | 2004-03-22 | Dennis A. Guritza | Bio-supportive matrices, methods of making and using the same |
| US6555228B2 (en) | 2000-10-16 | 2003-04-29 | Dennis A. Guritza | Bio-supportive medium, and methods of making and using the same |
| US9056048B2 (en) | 2001-08-16 | 2015-06-16 | The Trustees Of The University Of Pennsylvania | Synthesis and use of cationic steroids for anti-inflammatory drug therapy |
| JP2005511734A (ja) | 2001-12-07 | 2005-04-28 | スリル バイオメディカル コーポレイション | 癌治療用のシクロアルキル置換ポリアミンおよびそれらの合成方法 |
| US7731985B2 (en) | 2002-03-15 | 2010-06-08 | Ciba Specialty Chemicals Corporation | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
| US7144920B2 (en) | 2002-09-23 | 2006-12-05 | Mediquest Therapeutics, Inc. | Polyamine analogs that activate antizyme frameshifting |
| FR2860129A1 (fr) | 2003-09-30 | 2005-04-01 | Antoine Vanlaer | Combinaison biocide a base de h202 et d'amine, procede et utilisation desinfectante et antimicrobienne notamment vis-a-vis du biofilm bacterien |
| WO2005105729A1 (en) | 2004-02-13 | 2005-11-10 | Mediquest Therapeutics, Inc. | Polyamine analogs that activate antizyme frameshifting |
| BRPI0614805A2 (pt) | 2005-08-10 | 2011-04-12 | Univ Johns Hopkins | poliaminas úteis como produtos terapêuticos antiparasìticos e anticáncer e como inibidores de demetilase lisina-especìficos |
| GB0526240D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| WO2008101084A2 (en) | 2007-02-15 | 2008-08-21 | National Jewish Medical And Research Center | Methods and compositions for the disruption of biofilms |
| WO2008105441A1 (ja) | 2007-02-27 | 2008-09-04 | Ajinomoto Co., Inc. | リン吸収抑制活性を有するポリアミノ酸化合物及びリン吸収抑制剤 |
| US20080274929A1 (en) | 2007-05-01 | 2008-11-06 | Whitekettle Wilson K | Method for removing microbes from surfaces |
| FR2925491B1 (fr) | 2007-12-19 | 2010-09-03 | Oz Biosciences Sas | Nouvelle classe de lipides cationiques pour le transport d'agents actifs dans les cellules |
| US20110117032A1 (en) | 2008-07-22 | 2011-05-19 | Donna Gilding | Santising compositions and methods |
| US9212131B2 (en) | 2009-06-19 | 2015-12-15 | University Of Central Florida Research Foundation, Inc. | Polyamine transport inhibitors as novel therapeutics |
| FR2982611B1 (fr) | 2011-11-16 | 2014-01-03 | Univ Bretagne Occidentale | Procedes de preparation de composes tetraazacycloalcanes fonctionnels a l'aide d'un compose cyclique bisaminal particulier. |
| US9346741B2 (en) | 2012-03-28 | 2016-05-24 | University Of Central Florida Research Foundation, Inc. | Polyamine transport selective therapeutic agents with enhanced stability |
| WO2014078801A1 (en) | 2012-11-16 | 2014-05-22 | President And Fellows Of Harvard College | Methods and compositions comprising guanidines for treating biofilms |
| US8853278B1 (en) | 2013-05-22 | 2014-10-07 | Curza Global, Llc | Compositions comprising a biocidal polyamine |
| US9439433B2 (en) | 2013-05-22 | 2016-09-13 | Curza Global, Llc | Compositions and methods comprising a biocidal polyamine |
| WO2017147335A1 (en) | 2016-02-24 | 2017-08-31 | Rutgers, The State University Of New Jersey | Bacterial efflux pump inhibitors |
| WO2017218922A2 (en) * | 2016-06-17 | 2017-12-21 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of bacterial infections |
| AU2018249550B2 (en) | 2017-04-05 | 2023-11-30 | Curza, Inc. | Compositions and methods comprising a triaryl polyamine |
-
2018
- 2018-04-05 AU AU2018249550A patent/AU2018249550B2/en active Active
- 2018-04-05 JP JP2019554606A patent/JP7041166B2/ja active Active
- 2018-04-05 CN CN201880037491.3A patent/CN110785082B/zh active Active
- 2018-04-05 EP EP18720857.4A patent/EP3606344B1/en active Active
- 2018-04-05 WO PCT/US2018/026320 patent/WO2018187615A1/en not_active Ceased
- 2018-04-05 CA CA3058813A patent/CA3058813A1/en active Pending
-
2019
- 2019-10-04 US US16/593,143 patent/US11352315B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004030672A1 (en) * | 2002-10-02 | 2004-04-15 | Merck Patent Gmbh | Use of 4 amino-quinazolines as anti cancer agents |
| WO2012151554A1 (en) * | 2011-05-04 | 2012-11-08 | President And Fellows Of Harvard College | Polyamines for treating biofilms |
| CN105407729A (zh) * | 2013-05-22 | 2016-03-16 | 库扎环球有限责任公司 | 包含聚胺的组合物和方法 |
Non-Patent Citations (4)
| Title |
|---|
| A Systematic Study of the Photophysical Processes in Polydentate Triphenylene-Functionalized Eu3+, Tb3+, Nd3+, Yb3+, and Er3+ Complexes;Klink, Stephen I.等;《J. Phys. Chem. A》;20000523;第104卷(第23期);5457-5468 * |
| Quantitative structure-activity relationship analysis;Strekowski, Lucjan 等;《Journal of Medicinal Chemistry》;19910201;第34卷(第2期);580-588 * |
| Structure-Activity Relationships of Methoctramine-Related Polyamines asMuscular Nicotinic Receptor Noncompetitive Antagonists. 2.1 Role of Polymethylene Chain Lengths Separating Amine Functions and of Substituents on the Terminal Nitrogen Atoms.;Michela Rosini 等;《J. Med. Chem.》;20020321;第45卷(第9期);1860-1878 * |
| Tunable emission in lanthanide coordination polymer gels based on a rationally designed blue emissive gelator;Sutar, Papri 等;《Chemical Communications》;20150513;第51卷(第48期);9876-9879 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018187615A1 (en) | 2018-10-11 |
| CN110785082A (zh) | 2020-02-11 |
| EP3606344A1 (en) | 2020-02-12 |
| EP3606344B1 (en) | 2022-08-17 |
| US11352315B2 (en) | 2022-06-07 |
| AU2018249550B2 (en) | 2023-11-30 |
| US20200031757A1 (en) | 2020-01-30 |
| CA3058813A1 (en) | 2018-10-11 |
| NZ757876A (en) | 2024-05-31 |
| AU2018249550A1 (en) | 2019-10-31 |
| JP7041166B2 (ja) | 2022-03-23 |
| JP2020520893A (ja) | 2020-07-16 |
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Legal Events
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |