AU2018249550B2 - Compositions and methods comprising a triaryl polyamine - Google Patents

Compositions and methods comprising a triaryl polyamine Download PDF

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Publication number
AU2018249550B2
AU2018249550B2 AU2018249550A AU2018249550A AU2018249550B2 AU 2018249550 B2 AU2018249550 B2 AU 2018249550B2 AU 2018249550 A AU2018249550 A AU 2018249550A AU 2018249550 A AU2018249550 A AU 2018249550A AU 2018249550 B2 AU2018249550 B2 AU 2018249550B2
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AU
Australia
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independently selected
group
aspects
compound
biofilm
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AU2018249550A
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AU2018249550A1 (en
Inventor
Travis J. HAUSSENER
Ryan E. LOOPER
Hariprasada R. Kanna REDDY
Paul R. Sebahar
Dustin Williams
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Curza Inc
University of Utah Research Foundation Inc
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Curza Inc
University of Utah Research Foundation Inc
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Assigned to UNIVERSITY OF UTAH RESEARCH FOUNDATION, Curza, Inc. reassignment UNIVERSITY OF UTAH RESEARCH FOUNDATION Amend patent request/document other than specification (104) Assignors: CURZA GLOBAL, LLC, UNIVERSITY OF UTAH RESEARCH FOUNDATION
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/04Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AU2018249550A 2017-04-05 2018-04-05 Compositions and methods comprising a triaryl polyamine Active AU2018249550B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762482106P 2017-04-05 2017-04-05
US62/482,106 2017-04-05
PCT/US2018/026320 WO2018187615A1 (en) 2017-04-05 2018-04-05 Compositions and methods comprising a triaryl polyamine

Publications (2)

Publication Number Publication Date
AU2018249550A1 AU2018249550A1 (en) 2019-10-31
AU2018249550B2 true AU2018249550B2 (en) 2023-11-30

Family

ID=62067821

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018249550A Active AU2018249550B2 (en) 2017-04-05 2018-04-05 Compositions and methods comprising a triaryl polyamine

Country Status (7)

Country Link
US (1) US11352315B2 (enExample)
EP (1) EP3606344B1 (enExample)
JP (1) JP7041166B2 (enExample)
CN (1) CN110785082B (enExample)
AU (1) AU2018249550B2 (enExample)
CA (1) CA3058813A1 (enExample)
WO (1) WO2018187615A1 (enExample)

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* Cited by examiner, † Cited by third party
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BRPI0811530B1 (pt) 2007-05-14 2019-01-02 Research Foundation Of State Univ Of New York composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície
US11274144B2 (en) 2013-06-13 2022-03-15 Research Institute At Nationwide Children's Hospital Compositions and methods for the removal of biofilms
HK1255383A1 (zh) 2015-07-31 2019-08-16 The Research Institute At Nationwide Children's Hospital 去除生物膜的肽及抗體
EP3365027B1 (en) 2015-10-14 2022-03-30 Research Institute at Nationwide Children's Hospital Hu specific antibodies and their use in inhibiting biofilm
AU2018249550B2 (en) 2017-04-05 2023-11-30 Curza, Inc. Compositions and methods comprising a triaryl polyamine
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
WO2020006528A2 (en) * 2018-06-29 2020-01-02 Research Institute At Nationwide Children's Hospital Compositions and methods for mediating eps
MX2021003838A (es) 2018-10-05 2021-05-27 Res Inst Nationwide Childrens Hospital Derivados de proteina hmgb1 para la eliminacion de biopeliculas.
WO2021207247A1 (en) * 2020-04-07 2021-10-14 Kalin Health Llc Spermidine-supplemented food products

Citations (1)

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WO2004030672A1 (en) * 2002-10-02 2004-04-15 Merck Patent Gmbh Use of 4 amino-quinazolines as anti cancer agents

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US4340756A (en) 1981-02-04 1982-07-20 Merck & Co., Inc. Polyamine compounds as antibacterial agents
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4505861A (en) 1982-07-23 1985-03-19 University Of Florida Methods and intermediates for the preparation of spermidine, homospermidine and norspermidine
US5316757A (en) 1984-10-18 1994-05-31 Board Of Regents, The University Of Texas System Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups
HUT74005A (en) 1993-02-23 1996-10-28 Merrell Pharma Inc Polyamine derivatives as radioprotective agents and pharmaceutical compositions containing them
US5583239A (en) 1995-05-30 1996-12-10 Lehigh University Antimicrobial sterol conjugates
EP0955044B1 (en) 1995-06-26 2005-11-16 Chelator LLC Method of inhibiting bacterial or fungal growth using a complexing agent
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US7425579B2 (en) 1998-04-21 2008-09-16 Universite Laval Methods for inhibiting activity of polyamine transporters
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US6395189B1 (en) 1999-03-01 2002-05-28 Polymer Ventures, Inc. Method for the control of biofilms
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US6555228B2 (en) 2000-10-16 2003-04-29 Dennis A. Guritza Bio-supportive medium, and methods of making and using the same
US9056048B2 (en) 2001-08-16 2015-06-16 The Trustees Of The University Of Pennsylvania Synthesis and use of cationic steroids for anti-inflammatory drug therapy
JP2005511734A (ja) 2001-12-07 2005-04-28 スリル バイオメディカル コーポレイション 癌治療用のシクロアルキル置換ポリアミンおよびそれらの合成方法
US7731985B2 (en) 2002-03-15 2010-06-08 Ciba Specialty Chemicals Corporation 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces
US7144920B2 (en) 2002-09-23 2006-12-05 Mediquest Therapeutics, Inc. Polyamine analogs that activate antizyme frameshifting
FR2860129A1 (fr) 2003-09-30 2005-04-01 Antoine Vanlaer Combinaison biocide a base de h202 et d'amine, procede et utilisation desinfectante et antimicrobienne notamment vis-a-vis du biofilm bacterien
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BRPI0614805A2 (pt) 2005-08-10 2011-04-12 Univ Johns Hopkins poliaminas úteis como produtos terapêuticos antiparasìticos e anticáncer e como inibidores de demetilase lisina-especìficos
GB0526240D0 (en) 2005-12-22 2006-02-01 Novartis Ag Organic compounds
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FR2925491B1 (fr) 2007-12-19 2010-09-03 Oz Biosciences Sas Nouvelle classe de lipides cationiques pour le transport d'agents actifs dans les cellules
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WO2004030672A1 (en) * 2002-10-02 2004-04-15 Merck Patent Gmbh Use of 4 amino-quinazolines as anti cancer agents

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Sutar, P. et al, Chemical Communications, 2015, 51(48), 9876-79 *

Also Published As

Publication number Publication date
WO2018187615A1 (en) 2018-10-11
CN110785082A (zh) 2020-02-11
EP3606344A1 (en) 2020-02-12
EP3606344B1 (en) 2022-08-17
US11352315B2 (en) 2022-06-07
US20200031757A1 (en) 2020-01-30
CA3058813A1 (en) 2018-10-11
NZ757876A (en) 2024-05-31
AU2018249550A1 (en) 2019-10-31
JP7041166B2 (ja) 2022-03-23
CN110785082B (zh) 2021-12-28
JP2020520893A (ja) 2020-07-16

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Free format text: FORMER NAME(S): CURZA GLOBAL, LLC; UNIVERSITY OF UTAH RESEARCH FOUNDATION

Owner name: CURZA, INC.

Free format text: FORMER NAME(S): CURZA GLOBAL, LLC; UNIVERSITY OF UTAH RESEARCH FOUNDATION

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