CN110769800B - Cosmetic composition containing fullerene - Google Patents

Abstract

The invention provides a cosmetic composition which can easily disperse fullerene in water. Also disclosed is a composition for cosmetic materials, which is prepared using such a composition and has a transparent appearance and excellent dispersion stability in an aqueous dispersion containing fullerene. A cosmetic composition containing the following components (A) to (E) was used. Preferably the composition has a bicontinuous structure. (A) An oil solution in which 0.001 to 0.3% of fullerene is dissolved; (B) a nonionic surfactant; (C) a polyol; (D) an oil agent; (E) and (3) water.

Description

Cosmetic composition containing fullerene

Technical Field

The present invention relates to a composition for a cosmetic material containing fullerene and a cosmetic material using the composition for a cosmetic material.

Background

In recent years, the use of fullerene for cosmetics has been widely attempted, and in particular, the tendency of fullerene has been becoming stronger after the active oxygen eliminating ability of fullerene has been known. In addition to the ability to eliminate active oxygen, various examples of applications of fullerene in cosmetics are known, for example, application as a pigment (patent document 1), application as an ultraviolet absorber (patent document 2), application as a melanin inhibitor (patent document 3), application as a wrinkle inhibitor (patent document 4), application as a hair damage inhibitor (patent document 5), and the like.

On the other hand, since fullerene is a hardly soluble substance, and particularly is insoluble in water, it is very difficult to directly blend fullerene in an aqueous formulation. As a method for solving such problems, for example, a method of forming a composite with a water-soluble polymer such as polyvinylpyrrolidone and dispersing the composite in water is known (patent document 6). However, this method has a problem that the water-soluble polymer used may have an unfavorable feel and the effect of fullerene cannot be sufficiently exhibited depending on the application. As another method, a method of encapsulating a liposome using a phospholipid and dispersing the liposome in water is known (patent document 7). However, since the preparation of liposomes requires complicated steps, it cannot be said that the method for preparing an aqueous dispersion of fullerene is a simple method. As another method, a method is known in which fullerene is once dissolved in hydrocarbon oil or the like, and then emulsified with a surfactant (patent document 8). However, it cannot be said that the preparation is certainly simple in this method, and the obtained aqueous dispersion is poor in transparency, and the dispersion stability is not sufficient.

Documents of the prior art

Patent document

Patent document 1: japanese patent laid-open No. H06-192039.

Patent document 2: japanese patent laid-open No. H09-278625.

Patent document 3: japanese patent laid-open No. 2007-131536.

Patent document 4: international publication No. 2009/113426.

Patent document 5: japanese patent laid-open publication No. 2016 + 16992.

Patent document 6: japanese patent laid-open No. 2005-060380.

Patent document 7: japanese patent laid-open No. 2009 and 242380.

Patent document 8: japanese patent laid-open No. 2008-255107.

Disclosure of Invention

Problems to be solved by the invention

The present invention addresses the problem of providing a cosmetic composition in which fullerenes can be easily dispersed in water.

Another object of the present invention is to provide a composition for a cosmetic material, which is prepared using the composition, and which has a transparent appearance and excellent dispersion stability in an aqueous dispersion containing fullerene.

Means for solving the problems

The present inventors have conducted intensive studies to solve the above problems, and as a result, have found that fullerene can be easily dispersed in water by using a cosmetic composition containing the following components (a) to (E), and the above problems can be solved, and have completed the present invention.

(A) An oil solution in which 0.001 to 0.3 wt% of fullerene is dissolved; (B) a nonionic surfactant; (C) a polyol; (D) an oil agent; (E) and (3) water.

Further, the present inventors have found that a composition for cosmetic materials has a bicontinuous structure, and an aqueous dispersion containing fullerene prepared by using the composition has a transparent appearance and excellent dispersion stability, and have solved the above-mentioned problems, thereby completing the present invention.

ADVANTAGEOUS EFFECTS OF INVENTION

By using the cosmetic composition of the present invention, fullerene can be easily dispersed in water.

Further, since the cosmetic composition has a bicontinuous structure, the obtained aqueous dispersion has a transparent appearance and excellent dispersion stability.

Drawings

FIG. 1 is a graph showing the relationship between the number of destruction times after hair dyeing and the number of times of measurement of. DELTA.E in example 51.

FIG. 2 is a graph showing the results of quantifying the amount of cysteine in hair caused by ultraviolet rays with respect to the cosmetic composition of example 1.

Detailed Description

The cosmetic composition of the present invention contains the following components (a) to (E) as essential components.

(A) An oil solution in which 0.001 to 0.3 wt% of fullerene is dissolved; (B) a nonionic surfactant; (C) a polyol; (D) an oil agent; (E) and (3) water.

The component (a) used in the present invention is an oil agent in which fullerene is dissolved in an oil agent at a concentration of 0.001 to 0.3 wt%, and the concentration of fullerene is more preferably 0.01 to 0.28 wt%, and most preferably 0.03 to 0.25 wt%. The method of dissolving fullerene in the oil agent is not particularly limited, and the fullerene can be prepared by dissolving fullerene in the oil agent and the oil agent under heating while stirring. Alternatively, the fullerene can be dissolved at a higher concentration by the method described in Japanese patent application laid-open No. 2011-256095. Specifically, the fullerene can be prepared by dissolving fullerene in a solvent such as toluene or cyclohexane, adding an oil agent so that the fullerene has a predetermined concentration, and distilling off the solvent under reduced pressure.

The fullerene used as the component (A) in the present invention is a general term for a fullerene having a spherical shell-like molecule composed of carbon atoms, and the carbon number thereof is known as C₆₀、C₇₀、C₇₆、C₇₈、C₈₂、C₈₄、C₉₀、C₉₆. Any of such fullerenes can be used in the present invention. These fullerenes may be used alone or in combination of two or more. Among them, C is preferably used from the viewpoint of solubility in the oil agent and easy availability₆₀、C₇₀And mixtures thereof.

The oil agent used in the component (a) of the present invention is not particularly limited as long as it dissolves fullerene, and specifically, lactone derivatives, ester oils, vegetable oils, hydrocarbon oils, and the like can be used. Among these, from the viewpoint of stabilizing the fullerene and dissolving it at a high concentration, the lactone derivative and the ester oil are preferable, and both are most preferably used.

More specifically, the lactone derivative used as the component (a) includes a compound represented by the following general formula (1).

Chemical formula 1

(wherein n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms)

Specific examples of R in the general formula (1) include nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl, heneicosyl, docosyl, and the like, and among these, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, eicosyl, and heneicosyl are more preferable, and decyl, dodecyl, tetradecyl, and octadecyl are most preferable, from the viewpoints of availability of raw materials and ease of synthesis. In addition, n in the formula is preferably a compound of 1. The most preferred lactone derivatives include γ -tetradecanolide, γ -hexadecanolide, γ -octadecanolactone, γ -eicosanolide and γ -docosanoic acid.

As the ester oil used in the component (A), more specifically, it is preferable to mention glycerol triethylhexanoate, glycerol trioctanoate, glycerol tricaprate, glycerol tri (caprylic/capric) ate, glycerol trioleate, glycerol triisostearate, trimethylolpropane triethylhexanoate, pentaerythritol tetraethylhexanoate, 3-methyl-1, 5-pentanediol di-pivalate, 2, 4-diethyl-1, 5-pentanediol di-pivalate, cetyl ethyl hexanoate, hexyldecanol ethyl hexanoate, isononyl isononanoate, isodecyl isononanoate, isotridecanol isononanoate, isodecyl pivalate, isotridecyl pivalate, isostearyl alcohol pivalate, octyldodecanol neodecanoate, isopropyl myristate, hexyldecanol myristate, octyldodecanol myristate, Isopropyl palmitate, ethylhexyl palmitate, cetyl palmitate, octyldodecanol palmitate, ethyl oleate, oleyl oleate, octyldodecanol oleate, isopropyl isostearate, octyldodecanol erucate, isopropyl lanolate, octyldodecanol lanolate, dioctyl carbonate, diethylhexyl succinate, diisopropyl adipate, diisobutyl adipate, diethyl sebacate, diisopropyl sebacate, diethylhexyl sebacate, triethyl citrate, diisostearyl malate, and the like. Among them, preferred are triethylhexanoic acid glycerol ester, tri (caprylic/capric) glycerol ester, cetyl ethyl hexanoate, ethylhexyl palmitate, and diethylhexyl sebacate, and most preferred are tri (caprylic/capric) glycerol ester and cetyl ethyl hexanoate.

As the nonionic surfactant of the component (B) used in the present invention, one or more selected from polyglycerin fatty acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene fatty acid esters, and polyoxyethylene alkyl ethers can be used. These nonionic surfactants may be used alone or in combination of two or more.

Specific examples of the polyglycerin fatty acid ester include monoesters, diesters, triesters, tetraesters and the like of a fatty acid having 8 to 22 carbon atoms and a polyglycerin having a polymerization degree of 2 to 20. Among them, preferable examples of the polyglycerin fatty acid ester include polyglycerin caprylate, polyglycerin caprate, polyglycerin laurate, polyglycerin myristate, polyglycerin palmitate, polyglycerin stearate, polyglycerin oleate, polyglycerin isostearate, polyglycerin behenate, polyglycerin dioctanoate, polyglycerin didecanoate, polyglycerin dilaurate, polyglycerin dimyristate, polyglycerin dipalmitate, polyglycerin distearate, polyglycerin dioleate, polyglycerin diisostearate, polyglycerin dibehenate, polyglycerin tricaprylate, polyglycerin tricaprate, polyglycerin trilaurate, polyglycerin trimyristate, polyglycerin tripalmitate, polyglycerin tristearate, polyglycerin trioleate, polyglycerin triisostearate, polyglycerin tribehenate, and the like, and most preferable examples thereof are polyglycerin laurate, polyglycerin myristate, polyglycerin tripalmitate, polyglycerin tristearate, polyglycerin trioleate, polyglycerin triisostearate, and polyglycerin tribehenate, Polyglycerol stearate, polyglycerol isostearate, polyglycerol dilaurate, polyglycerol distearate, and polyglycerol diisostearate.

Specific examples of the polyoxyethylene glycerin fatty acid ester include monoesters, diesters, and triesters of glycerin polyoxyethylene adducts having a number of moles of polyoxyethylene (E.O: ethylene oxide) added of 4 to 200 and fatty acids having 8 to 22 carbon atoms. Among these, preferable polyoxyethylene glycerin fatty acid esters include polyoxyethylene glycerin caprylate, polyoxyethylene glycerin caprate, polyoxyethylene glycerin laurate, polyoxyethylene glycerin myristate, polyoxyethylene glycerin palmitate, polyoxyethylene glycerin stearate, polyoxyethylene glycerin oleate, polyoxyethylene glycerin isostearate, polyoxyethylene glycerin dicaprylate, polyoxyethylene glycerin dicaprate, polyoxyethylene glycerin dilaurate, polyoxyethylene glycerin dimyristate, polyoxyethylene glycerin dipalmitate, polyoxyethylene glycerin distearate, polyoxyethylene glycerin dioleate, polyoxyethylene glycerin diisostearate, polyoxyethylene glycerin tricaprylate, polyoxyethylene glycerin tricarballyl, polyoxyethylene glycerin trilaurate, polyoxyethylene glycerin trimyristate, polyoxyethylene glycerin tripalmitate, polyoxyethylene glycerin tricaprylate, polyoxyethylene glycerin trilaurate, polyoxyethylene glycerin trimyristate, polyoxyethylene glycerin tripalmitate, polyoxyethylene glycerin trilactate, polyoxyethylene glycerin dicaprylate, polyoxyethylene glycerin dicaprate, polyoxyethylene glycerin dicaprylate, polyoxyethylene glycerin dicarholate, etc, Polyoxyethylene glyceryl tristearate, polyoxyethylene glyceryl trioleate, polyoxyethylene glyceryl triisostearate and the like, and polyoxyethylene glyceryl laurate, polyoxyethylene glyceryl stearate and polyoxyethylene glyceryl isostearate are most preferable.

Specific examples of the polyoxyethylene sorbitan fatty acid ester include monoesters, diesters, triesters, tetraesters and the like of sorbitan polyoxyethylene adducts having a mole number of addition of polyoxyethylene (E.O) of 4 to 200 and fatty acids having 8 to 22 carbon atoms. Among them, preferable polyoxyethylene sorbitan fatty acid esters include polyoxyethylene sorbitan caprylate, polyoxyethylene sorbitan caprate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan myristate, polyoxyethylene sorbitan palmitate, polyoxyethylene sorbitan stearate, polyoxyethylene sorbitan oleate, polyoxyethylene sorbitan isostearate, polyoxyethylene sorbitan dicaprylate, polyoxyethylene sorbitan dicaprate, polyoxyethylene sorbitan dilaurate, polyoxyethylene sorbitan dimyristate, polyoxyethylene sorbitan dipalmitate, polyoxyethylene sorbitan distearate, polyoxyethylene sorbitan dioleate, polyoxyethylene sorbitan diisostearate, polyoxyethylene sorbitan distearate, polyoxyethylene sorbitan dioleate, polyoxyethylene sorbitan diisostearate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan dimyristate, polyoxyethylene sorbitan stearate, polyoxyethylene sorbitan dioleate, polyoxyethylene sorbitan diisostearate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan oleate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan dioleate, and polyoxyethylene sorbitan diisostearate, Polyoxyethylene sorbitan tricaprylate, polyoxyethylene sorbitan tricaprate, polyoxyethylene sorbitan trilaurate, polyoxyethylene sorbitan trimyristate, polyoxyethylene sorbitan tripalmitate, polyoxyethylene sorbitan tristearate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan triisostearate and the like, with polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan stearate, polyoxyethylene sorbitan isostearate, polyoxyethylene sorbitan trilaurate, polyoxyethylene sorbitan tristearate and polyoxyethylene sorbitan triisostearate being most preferred.

Specific examples of the polyoxyethylene fatty acid ester include monoesters and diesters of polyoxyethylene having a polyoxyethylene (E.O) added in a molar number of 4 to 200 and a fatty acid having 8 to 22 carbon atoms. Among them, preferable polyoxyethylene fatty acid esters include polyoxyethylene caprylate, polyoxyethylene caprate, polyoxyethylene laurate, polyoxyethylene myristate, polyoxyethylene palmitate, polyoxyethylene stearate, polyoxyethylene oleate, polyoxyethylene isostearate, polyoxyethylene behenate, polyoxyethylene dicaprylate, polyoxyethylene dicaprate, polyoxyethylene dilaurate, polyoxyethylene dimyristate, polyoxyethylene dipalmitate, polyoxyethylene distearate, polyoxyethylene dioleate, polyoxyethylene diisostearate, and polyoxyethylene dibehenate, and polyoxyethylene laurate, polyoxyethylene stearate, polyoxyethylene oleate, and polyoxyethylene isostearate are most preferable.

Specific examples of the polyoxyethylene alkyl ether include monoethers of polyoxyethylene having a polyoxyethylene (E.O) added in a molar number of 4 to 200 and an alkyl group having 8 to 22 carbon atoms. Among these, preferable polyoxyethylene alkyl ethers include polyoxyethylene octyl ether, polyoxyethylene caprylyl ether, polyoxyethylene lauryl ether, polyoxyethylene myristyl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene oleyl ether, polyoxyethylene isostearyl ether, polyoxyethylene behenyl ether, and the like, and polyoxyethylene lauryl ether, polyoxyethylene stearyl ether, and polyoxyethylene behenyl ether are most preferable.

The nonionic surfactant as the component (B) is preferably used in a mixture of two or more from the viewpoint of improving storage stability of the cosmetic composition, transparency of an aqueous dispersion prepared using the cosmetic composition, and dispersion stability. The HLB of the nonionic surfactant to be used is not particularly limited, and the HLB of the entire component (B) is preferably 5 to 16, more preferably 7 to 14. Among these nonionic surfactants, polyglycerol fatty acid esters are preferred, and polyglycerol laurate, polyglycerol stearate, polyglycerol isostearate, polyglycerol dilaurate, polyglycerol distearate, and polyglycerol diisostearate are most preferred from the viewpoint of improving storage stability of fullerene.

Examples of the polyhydric alcohol as the component (C) used in the present invention include glycerin, 1, 3-butanediol, propylene glycol, 3-methyl-1, 3-butanediol, 1, 3-propanediol, 2-methyl-1, 3-propanediol, trimethylolpropane, pentaerythritol, sorbitol, pentanediol, hexanediol, 1, 2-hexanediol, octylglycol, diglycerin, polyglycerol, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, and the like. These polyols may be used alone or in combination of two or more. Among them, glycerin and 1, 3-butanediol are preferable, and both are more preferable from the viewpoint of stability.

Examples of the oil agent as the component (D) used in the present invention include hydrocarbon oils such as dodecane, isododecane, hexadecane, isohexadecane, liquid paraffin, heavy liquid isoparaffin, light liquid isoparaffin, α -olefin oligomer, squalane, hydrogenated polyisobutene, and the like; coconut oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, macadamia nut oil, rose hip oil, argan nut oil, meadowfoam seed oil, almond oil, tea tree oil, peppermint oil, camellia oil, corn oil, rapeseed oil, sunflower seed oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil and other vegetable oils; triethylcaproic acid glyceride, tricaprylin, tricaprin, tri (caprylic/capric) glyceride, triolein, triisostearic acid glyceride, trimethylolpropane triethylhexanoate, pentaerythritol tetraethylhexanoate, 3-methyl-1, 5-pentanediol dineopentanoate, 2, 4-diethyl-1, 5-pentanediol dineopentanoate, cetyl ethylhexanoate, hexyldecanol ethylhexanoate, isononyl isononanoate, isodecyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecanol neodecanoate, isopropyl myristate, hexyldecanol myristate, octyldodecanol myristate, isopropyl palmitate, ethylhexyl palmitate, cetyl palmitate, isotridecyl palmitate, triisodecyl stearate neovalerate, isostearyl neodecanoate, glyceryl stearate neodecanoate, glyceryl palmitolate, glyceryl tricaprylate, glyceryl monostearate, pentaerythritol tetraoleate, glyceryl monostearate, glyceryl stearate, or a, Ester oils such as octyldodecanol palmitate, ethyl oleate, oleyl oleate, octyldodecanol oleate, isopropyl isostearate, octyldodecanol erucate, isopropyl lanolate, octyldodecanol lanolate, dioctyl carbonate, diethylhexyl succinate, diisopropyl adipate, diisobutyl adipate, diethyl sebacate, diisopropyl sebacate, diethylhexyl sebacate, triethyl citrate, diisostearyl malate, diisostearyl dilinoleate, diisostearyl alcohol dilinoleate, di (isostearyl alcohol/phytosterol) dilinoleate, di (phytosterol/octyldodecanol) N-lauroyl-L-glutamate, etc.; amphipathic ester oils such as polyglyceryl-10 (eicosanedioic acid/tetradecanedioic acid) ester, diethoxydiol succinate, and diethoxydiol cyclohexanedicarboxylate; lactone derivatives such as γ -tetradecanolide, γ -hexadecanolide, γ -octadecanolide, γ -eicosanolide and γ -docosanoic lactone; silicone oils such as polydimethylsiloxane, cyclomethicone and phenyl polydimethylsiloxane. These oil agents may be used alone or in combination of two or more, and may include the same oil agents as those used for the component (a). In addition, an oil component generally used in cosmetics may be added within a range not impairing the effects of the present invention. Among these, from the viewpoint of stability of the cosmetic composition, it is preferable to contain a hydrocarbon oil such as liquid paraffin or squalane as an essential component, and it is preferable to contain the hydrocarbon oil in the component (D) in an amount of 50% by weight or more, and it is more preferable to contain the hydrocarbon oil in an amount of 70% by weight or more.

The water as the component (E) used in the present invention is not particularly limited as long as it is water that can be generally used for cosmetics, and purified water, ion-exchanged water, distilled water, natural water, deep seawater, hydrogen-rich water, and the like can be used. The pH may be adjusted with an acid, an alkali, a buffer, a chelating agent, or the like, or a preservative may be added.

The cosmetic composition of the present invention contains the above-mentioned components (a) to (E), but preferably has a bicontinuous structure from the viewpoints of improving storage stability of the cosmetic composition and transparency and dispersion stability of an aqueous dispersion prepared using the cosmetic composition. In the present invention, the bicontinuous structure refers to a state in which both the aqueous phase and the oil phase form a continuous phase, and is different from a general emulsion form in which the oil phase or the aqueous phase is dispersed in a medium having the aqueous phase or the oil phase as a continuous phase. In the case of having a bicontinuous structure, since both the aqueous phase and the oil phase form a continuous phase, the composition is uniformly colored to the hue of each pigment in both the case of adding a liquid in which a water-soluble pigment is dissolved in water and the case of adding a liquid in which an oil-soluble pigment is dissolved in oil. The confirmation of the bicontinuous structure can be performed using this method. In addition, it can also be confirmed by a method combining observation by an electron microscope using a freeze fracture transfer method, observation of appearance, observation using an optical polarization microscope, measurement of electric conductivity, and the like.

The content of each component of the cosmetic composition of the present invention is preferably 1 to 20% by weight of the component (a), 15 to 45% by weight of the component (B), 10 to 35% by weight of the component (C), 5 to 35% by weight of the component (D), and 10 to 40% by weight of the component (E), and more preferably 5 to 15% by weight of the component (a), 20 to 40% by weight of the component (B), 15 to 30% by weight of the component (C), 10 to 25% by weight of the component (D), and 15 to 35% by weight of the component (E), from the viewpoint of forming a bicontinuous structure. The method for producing the cosmetic composition of the present invention is not particularly limited, and the cosmetic composition can be produced by uniformly stirring the components.

The aqueous dispersion containing fullerene can be easily prepared by adding the cosmetic composition of the present invention obtained as described above to an aqueous medium and stirring the mixture. In this case, a special device such as a vortex mixer or a homogenizer is not required, and the production can be sufficiently performed by the stirring capability of a propeller or a stirrer. Further, the dispersion can be produced at room temperature without heating. The fullerene-containing water dispersion obtained as described above has a transparent appearance and very good dispersion stability. In the present invention, the appearance of the transparent film is a transparent film to the extent that the transparent film can be seen through the liquid from the back when the sample is placed in a glass bottle having a diameter of 3.5cm and viewed from the lateral direction. When the turbidity was measured by a spectrophotometer, the sample was placed in a cuvette having a thickness of 1cm, and the transmittance was 60% or more when measured at a wavelength of 600 nm.

The amount of the composition for a cosmetic material of the present invention to be blended in a cosmetic material is not particularly limited, but is preferably 0.01 to 30% by mass, and more preferably 0.05 to 10% by mass, from the viewpoint of appearance and stability of the obtained cosmetic material.

The cosmetic material containing the cosmetic composition of the present invention may contain, if necessary, water to such an extent that the effect of the present invention is not impaired, and additional components usually added to cosmetic materials, such as an oily base, a surfactant, alcohols, a moisturizer, a polymer/thickening/gelling agent, an antioxidant, an antiseptic, a bactericide, a chelating agent, a pH adjuster/acid/base, an ultraviolet absorber, a whitening agent, a solvent, a exfoliating/dissolving agent, an antipruritic agent, an anti-inflammatory agent, an antiperspirant, a refreshing agent, an antihistamine, an astringent, an irritant, a hair growth promoting agent/blood circulation promoter, a reducing agent/oxidizing agent, polymer powder, hydroxy acids, vitamins and derivatives thereof, saccharides and derivatives thereof, organic acids, enzymes, nucleic acids, hormones, inorganic powders, a skin-caring agent, a skin-caring skin-protecting skin-against skin-aging, and the like, Spices, pigments, and the like.

The oily base is preferably a higher alcohol such as cetyl alcohol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetearyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, 2-octyldodecanol, or dimer alcohol; aralkyl alcohols and derivatives such as benzyl alcohol; higher fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, palmitoleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexadecanoic acid, isoeicosanoic acid (antieicosanoic acid), branched long-chain fatty acids, dimer acids, and hydrodimer acids, and metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium salts, and sodium salts, and nitrogen-containing derivatives such as amides; hydrocarbons such as liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin, α -olefin oligomer, polyisobutylene, hydrogenated polyisobutylene, polybutene, squalane derived from olive, squalene, vaseline, and paraffin wax; waxes such as candelilla wax, carnauba wax, rice wax, wood wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, Fischer Tropsch wax, polyethylene wax, and ethylene-propylene copolymer; vegetable oils and fats such as coconut oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, macadamia nut oil, rose hip oil, meadowfoam seed oil, apricot kernel oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower seed oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil and the like; animal fats such as beef tallow, butterfat, horse fat, egg oil, mink oil, and turtle oil; animal waxes such as spermaceti, lanolin, and atlantic pectoral porgy; lanolin such as liquid lanolin, reduced lanolin, adsorption-refined lanolin, acetic acid liquid lanolin, hydroxylated lanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol acetate, (cetyl alcohol/lanolin alcohol) acetate; sphingomyelin such as lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingomyelin, phosphatidic acid, cyclic lysophosphatidic acid or a salt thereof, lysolecithin, and the like; phospholipid derivatives such as hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated yolk phospholipid, and partially hydrogenated yolk phospholipid; sterols such as cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, phytosterol, and cholic acid; sapogenins; saponins; cholesterol acetate, cholesterol pelargonate, cholesterol stearate, cholesterol isostearate, cholesterol oleate, di (cholesterol/behenyl/octyldodecanol) N-lauroyl-L-glutamate, di (cholesterol/octyldodecanol) N-lauroyl-L-glutamate, di (phytosterol/behenyl/octyldodecanol) N-lauroyl-L-glutamate, acyl sarcosine alkyl esters such as di (phytosterol/behenyl/octyldodecanol) N-lauroyl-L-glutamate, and N-lauroyl sarcosine isopropyl ester, cholesterol ester of 12-hydroxystearic acid, cholesterol ester of macadamia nut oil fatty acid, phytosterol ester of sunflower oil fatty acid, cholesterol isostearate ester of macadamia nut oil, cholesterol oleate, cholesterol ester of macadamia nut oil, and fatty acid, Sterol esters such as phytosterol isostearate, soft lanolin fatty acid cholesterol ester, hard lanolin fatty acid cholesterol ester, branched long chain fatty acid cholesterol ester, and long chain alpha-hydroxy fatty acid cholesterol ester; lipid complexes such as phospholipid/cholesterol complexes and phospholipid/phytosterol complexes; octyldodecanol myristate, hexyldecanol myristate, octyldodecanol isostearate, cetyl palmitate, octyldodecanol palmitate, cetyl octanoate, hexyldecanol octanoate, isotridecyl isononanoate, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecanol neodecanoate, oleyl oleate, octyldodecanol ricinoleate, octyldodecanol lanolate, dioctyl carbonate, hexyldecyl dimethyloctanoate, octyldodecanol erucate, hydrogenated castor oil isostearate, ethyl oleate, avocado oil fatty acid ethyl ester, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, isopropyl lanolate, isopropyl oleate, isopropyl myristate, octyl palmitate, isopropyl myristate, isopropyl palmitate, isopropyl myristate, isopropyl palmitate, and the like, Monoalcohol carboxylic acid esters such as methylheptyl laurate, methylheptyl myristate, methylheptyl palmitate, methylheptyl isostearate, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyl octyl sebacate, diisobutyl adipate, dioctyl succinate, and triethyl citrate; oxoacid esters such as cetyl lactate, diisostearate malate, monoisostearate of hydrogenated castor oil, and gamma-erucic acid lactone; glyceryl tricaprylate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, glyceryl tri (caprylic/capric), glyceryl tri (caprylic/capric/myristic/stearic), hydrogenated rosin triglyceride (hydrogenated rosin ester), rosin triglyceride (rosin ester), glyceryl behenate, trimethylolpropane tricaprylate, trimethylolpropane triisostearate, neopentyl glycol dicaprylate, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1, 3-propanediol dicaprylate, propylene glycol dioleate, pentaerythritol tetracaprylate, hydrogenated rosin pentaerythritol, ditrimethylolpropane triethylhexanoate, ditrimethylolpropane (isostearic acid/sebacic) ester, pentaerythritol triethylhexanoate, glyceryl diisodecanoate, glyceryl diisocaprylate, glyceryl triisostearate, glyceryl diisodecanoate, glyceryl behenate, glyceryl tricaprylate, glyceryl monostearate, glyceryl stearate, and the, Polyhydric alcohol fatty acid esters such as dipentaerythritol (hydroxystearic acid/stearic acid/abietic acid) ester, diglycerin diisostearate, polyglycerin tetraisostearate, polyglycerin-10 nonaisostearate, polyglycerin-8 deca (erucic acid/isostearic acid/ricinoleic acid) ester, (hexyldecanoic acid/sebacic acid) diglycerin oligoester, ethylene glycol distearate, 3-methyl-1, 5-pentanediol dineovalerate, and 2, 4-diethyl-1, 5-pentanediol dineovalerate; alkyl ethers such as dioctyl ether; dimer acid or dimer alcohol derivatives such as diisopropyl dimelinoleate, diisostearyl alcohol dimer linoleate, di (isostearyl alcohol/phytosterol) dimer linoleate, (phytosterol/behenyl alcohol) dimer linoleate, (phytosterol/isostearyl alcohol/cetyl alcohol/stearyl alcohol/behenyl alcohol) dimer linoleate, dimer linoleate diisostearate, dimer linoleate hydrogenated rosin condensation product, hydrogenated castor oil dimer linoleate, and hydroxyalkyl dimer linoleate; fatty acid alkanolamides such as coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (Palmitamide MEA), palmitic acid diethanolamide (Palmitamide DEA), and coconut oil fatty acid methyl ethanolamide (cocamide methyl MEA); polydimethyl siloxane (dimethylpolysiloxane), high-polymerized polydimethyl siloxane (high-polymerized dimethylpolysiloxane), cyclomethicone (cyclomethicone, decamethylcyclopentasiloxane), phenyltrimethicone, diphenyl polydimethylsiloxane, phenyl polydimethylsiloxane, (aminoethyl aminopropyl methicone/polydimethylsiloxane) copolymer, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified silicone such as aminopropyl polydimethylsiloxane and amino-terminated polydimethylsiloxane, polyether-modified silicone such as cation-modified silicone and dimethicone copolyol, polyglycerin-modified silicone, sugar-modified silicone, carboxylic acid-modified silicone, phosphoric acid-modified silicone, sulfuric acid-modified silicone, alkyl-modified silicone, fatty acid-modified silicone, silicone rubber, amino-modified polydimethylsiloxane, and amino-terminated polydimethylsiloxane, and the like, and polyether-modified silicone such as sugar-modified silicone, carboxylic acid-modified silicone, phosphoric acid-modified silicone, sulfuric acid-modified silicone, alkyl-modified silicone, fatty acid-modified silicone, silicone rubber, silicone (silicone rubber, silicone (silicone rubber, silicone rubber, silicone, Silicones such as alkyl ether-modified silicone, amino acid-modified silicone, peptide-modified silicone, fluorine-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone, alkyl-modified and polyether-modified silicone, amidoalkyl-modified silicone, aminodiol-modified silicone, aminophenyl-modified silicone, and polysiloxane-oxyalkylene copolymer; fluorine-containing oils such as perfluorodecane, perfluorooctane and perfluoropolyether.

Preferred examples of the humectant/feel improver include polyhydric alcohols and polymers thereof such as glycerin, 1, 3-butanediol, propylene glycol, 3-methyl-1, 3-butanediol, 1, 3-propanediol, 2-methyl-1, 3-propanediol, trimethylolpropane, pentaerythritol, hexanediol, diglycerin, polyglycerol, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, and ethylene glycol-propylene glycol copolymer; glycol alkyl ethers such as diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, and diethylene glycol dibutyl ether; water-soluble esters such as polyglycerin-10 (eicosanedioic acid/tetradecanedioic acid) ester, polyglycerin-10-tetradecanedioic acid ester, and diethoxydiol cyclohexanedicarboxylate; sugar alcohols such as sorbitol, xylitol, erythritol, mannitol, and maltitol; saccharides and derivatives thereof such as glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (modified cyclodextrins such as α -, β -, γ -cyclodextrin, maltosyl, and hydroxyalkylated), β -glucan, chitin, chitosan, heparin and derivatives thereof, pectin, arabinogalactan, dextrin, dextran, glycogen, ethyl glucoside, and glucose ethyl methacrylate polymers or copolymers; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate; mucin sulfate, carinine sulfate, cutin sulfate, dermatan sulfate; tremella extract and tremella polysaccharide; fructans such as inulin and levan; fucoidan; tuberose polysaccharides, natural polysaccharides; organic acids such as citric acid, tartaric acid, and lactic acid, and salts thereof; urea; 2-pyrrolidone-5-carboxylic acid and sodium salts thereof; amino acids such as betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β -alanine, threonine, glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine and salts thereof; collagen, fish collagen, atelocollagen, gelatin, elastin, collagen degradation peptide, hydrolyzed collagen, hydroxypropylammonium chloride hydrolyzed collagen, elastin degradation peptide, keratin degradation peptide, hydrolyzed keratin, conchiolin degradation peptide, hydrolyzed conchiolin, silk protein degradation peptide, hydrolyzed silk, lauroyl hydrolyzed silk sodium, soybean protein degradation peptide, wheat protein degradation peptide, hydrolyzed wheat protein, casein degradation peptide, acylated peptide, and other protein peptides and derivatives thereof; acylated peptides such as palmitoyl oligopeptide, palmitoyl pentapeptide, and palmitoyl tetrapeptide; silyl peptides; lactobacillus culture solution, yeast extract, eggshell membrane protein, bovine submaxillary gland mucin, hypotaurine, sesame lignin glycoside, glutathione, albumin and whey; choline chloride, phosphorylcholine; animal/plant extract components such as placenta extract, elastin (エアラスチン), collagen, aloe extract, hamamelis water, luffa water, chamomile extract, licorice extract, comfrey extract, silk extract, rose palmatum extract, yarrow extract, eucalyptus extract, and sweet clover extract, and ceramides such as natural ceramides (type 1, type 2, type 3, type 4, type 5, and type 6), hydroxyceramide, pseudoceramide, glycosphingolipid, ceramide, and ceramide-containing extract.

Preferred examples of the surfactant include anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, and polymeric surfactants. The HLB of the surfactant is not particularly limited, and may be used in a range of from about 1 to about 20, and a surfactant having a low HLB and a surfactant having a high HLB are preferably combined. Preferred examples of the surfactant include anionic surfactants, and preferred examples of the anionic surfactant include fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate ester salts such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; polyoxyethylene alkyl sulfates such as sodium laureth sulfate, triethanolamine laureth sulfate, etc.; acyl N-methyl amino acid salts such as sodium cocoyl methyl taurate, potassium cocoyl methyl taurate, sodium lauroyl methyl taurate, sodium myristoyl methyl taurate, sodium lauroyl methyl alanine, sodium lauroyl sarcosinate, triethanolamine lauroyl sarcosinate, and sodium lauroyl glutamic acid methyl alanine; acyl amino acid salts such as sodium cocoyl glutamate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditetraethanolamine palmitoyl aspartate, triethanolamine cocoyl alanine, sodium lauroyl glutamate (ジラウロイルグルタミン acid リシン Na); polyoxyethylene alkyl ether acetates such as sodium laureth acetate; succinic acid ester salts such as sodium lauroyl monoethanolamide succinate; fatty acid alkanolamide ether carboxylate; an acyl lactate; polyoxyethylene fatty amine sulfates; fatty acid alkanolamide sulfates; fatty acid glyceride sulfates such as sodium hydrogenated coconut oil fatty acid glycerin sulfate; alkyl benzene polyoxyethylene sulfates; olefin sulfonates such as sodium alpha-olefin sulfonate; alkyl sulfosuccinates such as disodium lauryl alcohol sulfosuccinate and dioctyl sodium sulfosuccinate; alkyl ether sulfosuccinates such as disodium laureth sulfosuccinate, sodium monolauryl monoethanolamide polyoxyethylene sulfosuccinate, and sodium lauryl polypropylene glycol sulfosuccinate; alkyl benzene sulfonates such as sodium tetradecyl benzenesulfonate and triethanolamine tetradecyl benzenesulfonate; alkyl naphthalene sulfonate; an alkyl sulfonate; alpha-sulfo fatty acid methyl ester salts; acyl isethionate; alkyl glycidyl ether sulfonates; an alkyl sulfoacetate; alkyl ether phosphate ester salts such as sodium laureth phosphate, sodium dilauryl polyether phosphate, sodium trilauryl polyether phosphate and sodium monooleyl polyether phosphate (モノオレスリン acid ナトリウム); alkyl phosphate salts such as potassium lauryl phosphate; sodium caseinate; alkyl aryl ether phosphates; fatty acid amide ether phosphates; phospholipids such as phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or a salt thereof; silicone anionic surfactants such as carboxylic acid-modified silicones, phosphoric acid-modified silicones, and sulfuric acid-modified silicones; as the nonionic surfactant, polyoxyethylene alkyl ethers having different polyoxyethylene addition numbers such as laureth (polyoxyethylene lauryl ether), cetylpolyether (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), beheneth (polyoxyethylene behenyl ether), isosteeth (polyoxyethylene isostearyl ether), octyldodecyl polyether (polyoxyethylene octyldodecyl ether); polyoxyethylene alkylphenyl ethers; castor oils and hydrogenated castor oil derivatives such as polyoxyethylene hydrogenated castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearic acid diester, polyoxyethylene hydrogenated castor oil maleate, etc.; polyoxyethylene phytosterols; polyoxyethylene cholesterol; polyoxyethylene cholestanol; polyoxyethylene lanolin; polyoxyethylene reducing lanolin; polyoxyethylene/polyoxypropylene alkyl ethers such as polyoxyethylene/polyoxypropylene cetyl ether, polyoxyethylene/polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene/polyoxypropylene monobutyl ether, polyoxyethylene/polyoxypropylene hydrogenated lanolin, and polyoxyethylene/polyoxypropylene glyceryl ether; polyoxyethylene/polyoxypropylene glycols; polyoxypropylene glycol (poly) glycerol such as PPG-9 diglycerol; glycerol fatty acid partial esters such as glyceryl stearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, glyceryl oleate, glyceryl cocoate, glyceryl cottonseed oil fatty acid monoglyceride, erucic acid monoglyceride, glyceryl sesquioleate, alpha' -glyceryl pyroglutamate oleate, glyceryl monostearate, malic acid, etc.; polyglycerol-2 stearate, polyglycerol-3 stearate, polyglycerol-4 stearate, polyglycerol-5 stearate, polyglycerol-6 stearate, polyglycerol-8 stearate, polyglycerol-10 stearate, polyglycerol-6 distearate, polyglycerol-10 distearate, polyglycerol-2 tristearate, polyglycerol-10 decastearate, polyglycerol-2 isostearate, polyglycerol-3 isostearate, polyglycerol-4 isostearate, polyglycerol-5 isostearate, polyglycerol-6 isostearate, polyglycerol-8 isostearate, polyglycerol-10 isostearate, polyglycerol-2 diisostearate (diglyceryl diisostearate), polyglycerol-3 diisostearate, polyglycerol-5 diisostearate, polyglycerol-6 isostearate, polyglycerol-8 isostearate, polyglycerol-10 isostearate, polyglycerol-2 diisostearate (diglyceryl diisostearate), polyglycerol-3 diisostearate, Polyglyceryl fatty acid esters such as polyglyceryl-10 diisostearate, polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, polyglyceryl-3 oleate, polyglyceryl-4 oleate, polyglyceryl-5 oleate, polyglyceryl-6 oleate, polyglyceryl-8 oleate, polyglyceryl-10 oleate, polyglyceryl-6 dioleate, polyglyceryl-2 trioleate, and polyglyceryl-10 decaoleate; ethylene glycol mono-fatty acid esters such as ethylene glycol monostearate; propylene glycol mono fatty acid esters such as propylene glycol monostearate; pentaerythritol partial fatty acid ester; sorbitol moiety fatty acid ester; maltitol moiety fatty acid ester; a maltitol ether; sorbitan fatty acid esters such as sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerin sorbitan penta-2-ethylhexanoate, and diglycerin sorbitan tetra-2-ethylhexanoate; sugar derivative partial esters such as sucrose fatty acid ester, methyl glucoside fatty acid ester, trehalose undecylenate, etc.; alkyl glucosides such as octanoyl glucoside; an alkyl polyglucoside; glycolipids such as mannosylerythritol lipids; lanolin alcohol; reducing lanolin; polyoxyethylene fatty acid monoesters and diesters such as polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, and polyoxyethylene dioleate; polyoxyethylene/propylene glycol fatty acid esters; polyoxyethylene glycerin fatty acid esters such as polyoxyethylene monooleate including polyoxyethylene glycerin monostearate, polyoxyethylene glycerin monoisostearic acid, and polyoxyethylene glycerin triisostearic acid; polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, and polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol fatty acid esters such as polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol pentaoleate, and polyoxyethylene sorbitol monostearate; polyoxyethylene methyl glucoside fatty acid ester; polyoxyethylene alkyl ether fatty acid esters; polyoxyethylene animal and vegetable oils such as polyoxyethylene sorbitol beeswax; alkyl glyceryl ethers such as isostearyl alcohol glyceryl ether, chimyl alcohol, batyl alcohol and batyl alcohol; a polyol alkyl ether; polyoxyethylene alkyl amines; tetrapolyoxyethylene/tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponin and sophorolipid; polyoxyethylene fatty acid amides; fatty acid alkanolamides such as coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (palmitamide MEA), palmitic acid diethanolamide (palmitamide DEA), and coconut oil fatty acid methyl ethanolamide (cocamide methyl MEA); alkyl dimethyl amine oxides such as laurylamine oxide, cocoylamine oxide, stearylamine oxide and behenylamine oxide; alkyl ethoxy dimethyl amine oxide; polyoxyethylene alkyl mercaptans; silicone-based nonionic surfactants such as polyether-modified silicones including dimethicone copolyol, polysiloxane-oxyalkylene copolymers, polyglycerol-modified silicones, and sugar-modified silicones; as the cationic surfactant, alkyltrimethylammonium chlorides such as behenyltrimethylammonium chloride, stearyltrimethylammonium chloride, cetrimonium chloride and lauryltrimethylammonium chloride are preferable; alkyl trimethyl ammonium bromides such as stearyl trimethyl ammonium bromide; dialkyl dimethyl ammonium chlorides such as distearyl dimethyl ammonium chloride and dicocoyl dimethyl ammonium chloride; fatty acid amide-amines such as stearamidopropyldimethylamine and stearamidoethyldiethylamine, and salts thereof; alkyl ether amines such as stearyloxypropyldimethylamine and salts or quaternary salts thereof; fatty acid amide type quaternary ammonium salts such as long chain fatty acid (12 to 31) aminopropylethyldimethylammonium having a branched ethyl sulfate chain and lanolin fatty acid aminopropylethyldimethylammonium ethyl sulfate; polyoxyethylene alkylamines and salts or quaternary salts thereof; an alkylamine salt; fatty acid amide guanidine salts; alkyl ether ammonium salts (アルキルエーテルアミンモニウム salt); alkyl trialkylene glycol ammonium salts; benzalkonium salts; benzethonium salt; pyridinium salts such as cetylpyridinium chloride; imidazolium salts; an alkylisoquinolinium salt; a dialkyl morpholinium salt; polyamine fatty acid derivatives; amino-modified silicones such as aminopropylpolydimethylsiloxane and amino-terminated polydimethylsiloxane, cationic-modified silicones, cationic-modified and polyether-modified silicones, and silicone-based cationic surfactants such as amino-modified and polyether-modified silicones; as the amphoteric surfactant, preferred are N-alkyl-N, N-dimethylamino betaine such as lauryl betaine (lauryl dimethylaminoacetic acid betaine); fatty acid amide alkyl-N, N-dimethyl amino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline type betaines such as sodium cocoamphoacetate, sodium lauroamphoacetate and the like; alkyl sulfobetaines such as alkyldimethyltaurines; sulfuric acid type betaines such as alkyldimethylaminoethanol sulfate; phosphoric acid betaines such as alkyldimethylaminoethanol phosphate; phospholipids such as sphingomyelin such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine and sphingomyelin, lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated yolk phospholipid, partially hydrogenated yolk phospholipid, and hydrogenated lecithin; silicone amphoteric surfactants, etc.; as the high molecular surfactant, preferred are polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth, acrylic acid/methacrylic acid alkyl copolymers; silicon-based various surfactants.

Preferred examples of the polymer/thickener/gelling agent include guar gum, locust bean gum, quince seed (クイーンスシード), carrageenan, galactan, gum arabic, tara gum, tamarind seed, furcellaran, karaya gum, gum tragacanth, carageenan (Kyaragamu), tragacanth gum, pectin, salts such as pectic acid and sodium salt, salts such as alginic acid and sodium salt, and mannan; starch such as rice starch, corn starch, potato starch, and wheat starch; xanthan gum (キサンタンガム), dextran, succinoglucan (succinoglucan), curdlan, hyaluronic acid and its salt, xanthan gum (ザンサンガム), pullulan, gellan gum, chitin, chitosan, agar, brown algae extract, chondroitin sulfate, casein, collagen, gelatin, albumin; cellulose and its derivatives such as methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose and salts thereof such as sodium, methylhydroxypropylcellulose, sodium cellulose sulfate, dialkyldimethylammonium sulfate cellulose, crystalline cellulose, and cellulose powder; starch-based polymers such as soluble starch, carboxymethyl starch, methylhydroxypropyl starch and methyl starch, starch derivatives such as starch hydroxypropyltrimethylammonium chloride and corn starch aluminum octenylsuccinate; alginic acid derivatives such as sodium alginate and propylene glycol alginate; polyvinyl pyrrolidone (PVP), polyvinyl alcohol (PVA), a vinyl pyrrolidone-vinyl alcohol copolymer, polyvinyl methyl ether; polyethylene glycol, polypropylene glycol, polyoxyethylene-polyoxypropylene copolymer; amphoteric methacrylate copolymers such as (methacryloyloxyethylcarboxybetaine/alkyl methacrylate) copolymers and (acrylate/stearyl acrylate/ethylamine oxide methacrylate) copolymers; (polydimethylsiloxane/vinyl polydimethylsiloxane) crosspolymer, (alkyl acrylate/diacetone acrylamide) copolymer AMP; partially saponified products of polyvinyl acetate, maleic acid copolymers; vinyl pyrrolidone-dialkylaminoalkyl methacrylate copolymers; acrylic resin alkanolamine; polyester, water-dispersible polyester; polyacrylamide; polyacrylate copolymers such as polyethylacrylate, carboxyvinyl polymers, salts such as polyacrylic acid and sodium salt thereof, and acrylic acid-methacrylate copolymers; acrylic acid-methacrylic acid alkyl copolymers; cationized cellulose such as polyquaternium-10, diallyl dimethyl ammonium chloride-acrylamide copolymers such as polyquaternium-7, acrylic acid-diallyl dimethyl ammonium chloride copolymers such as polyquaternium-22, acrylic acid-diallyl dimethyl ammonium chloride-acrylamide copolymers such as polyquaternium-39, acrylic acid-cationized methacrylate copolymers, acrylic acid-cationized methacrylamide copolymers, acrylic acid-methyl acrylate-methacrylamidopropyl trimethyl ammonium chloride copolymers such as polyquaternium-47, and methacryloylcholine ester polymers; cationized polysaccharides such as cationized oligosaccharide, cationized dextran, guar gum hydroxypropyl trimethyl ammonium chloride and the like; a polyethyleneimine; a cationic polymer; copolymers such as 2-methacryloyloxyethyl phosphorylcholine polymers and butyl methacrylate copolymers, such as polyquaternium-51; high molecular emulsion such as acrylic resin emulsion, polyethylacrylate emulsion, polyalkylacrylate emulsion, polyvinyl acetate resin emulsion, natural rubber latex, synthetic latex and the like; nitrocellulose; polyurethanes and various copolymers; various silicones; silicone-based various copolymers such as acrylic-silicone graft copolymers; various fluorine-based polymers; 12-hydroxystearic acid and salts thereof; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; anhydrous silicic acid, fumed silica (ultrafine particle anhydrous silicic acid), magnesium aluminum silicate, sodium magnesium silicate, metal soap, dialkyl metal phosphate, bentonite, hectorite, organic modified clay mineral, sucrose fatty acid ester, and fructo-oligosaccharide fatty acid ester.

Preferred examples of the solvent/propellant include lower alcohols such as ethanol, 2-propanol (isopropanol), butanol, and isobutanol; glycols such as propylene glycol, 1, 3-butylene glycol, diethylene glycol, dipropylene glycol, and isoprene glycol; glycol ethers such as diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, and dipropylene glycol monoethyl ether; glycol ether esters such as ethylene glycol monoethyl ether acetate, diethylene glycol monoethyl ether acetate, and propylene glycol monoethyl ether acetate; glycol esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl alcohol, benzyloxy alcohol, propylene carbonate, dialkyl carbonate, acetone, ethyl acetate, N-methyl pyrrolidone; toluene; fluorocarbon, new generation freon; LPG, dimethyl ether, carbonic acid gas, and the like.

Preferred examples of the antioxidant include tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and/or derivatives thereof; erythorbic acid and derivatives thereof; sulfites such as sodium sulfite; bisulfite such as sodium bisulfite; thiosulfate salts such as sodium thiosulfate; a metabisulfite salt; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid and cysteine hydrochloride. Examples of the reducing agent include thioglycolic acid, cysteine, and cysteamine. Preferred examples of the oxidizing agent include hydrogen peroxide liquid, ammonium persulfate, sodium bromate, and percarbonic acid.

Preferred examples of the antibacterial agent or antiseptic include parabens (hydroxybenzoates) such as methyl paraben, ethyl paraben, propyl paraben, and butyl paraben; phenoxyethanol; 1, 2-alkanediols such as 1, 2-pentanediol, 1, 2-hexanediol, and 1, 2-octanediol; alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether (ethylhexyl glycerin); salicylic acid; sodium benzoate; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; an imidazolinyl urea; dehydroacetic acid and salts thereof; phenols; halogenated bisphenols such as triclosan, acid amides, and quaternary ammonium salts; trichlorocarbanilide (トリクロロカルバニド), zinc pyrithione, benzalkonium chloride, benzethonium chloride, sorbic acid, chlorhexidine gluconate, halocarban, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, p-chlorophenol, phenylphenol, and sodium phenylphenol; in the case where the phenethyl alcohol, the photosensitizers, the antibacterial zeolite, and the silver ion are used as an antibacterial agent or an antiseptic agent for the purpose of preservation, phenoxyethanol is more preferably used from the viewpoint of safety of cosmetic materials or skin external preparations; 1, 2-alkanediols such as 1, 2-pentanediol, 1, 2-hexanediol, and 1, 2-octanediol; alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether.

Preferable examples of the chelating agent include edetate (ethylenediamine tetraacetate salt) such as EDTA, EDTA2Na, EDTA3Na, EDTA4Na and the like; hydroxyethylethylenediamine triacetate such as HEDTA3 Na; pentetate (diethylenetriamine pentaacetate); phytic acid; phosphonic acids such as etidronic acid and salts such as sodium salts thereof; sodium oxalate; polyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate and phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethyl glycine, gluconic acid, ascorbic acid, succinic acid and tartaric acid. Examples of the pH adjuster/acid/base include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanolamine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1, 3-propanediol, 2-amino-2-hydroxymethyl-1, 3-propanediol, arginine, sodium hydroxide, potassium hydroxide, ammonia water, guanidine carbonate, and ammonium carbonate.

Preferred examples of the powder include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, lepidolite, biotite, vermiculite, magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, bentonite, montmorillonite, clay, mud, metal soap (e.g., zinc myristate, calcium palmitate, and aluminum stearate), calcium carbonate, red iron oxide, yellow iron oxide, black iron oxide, ultramarine, cyanotic, carbon black, titanium oxide, fine and ultrafine particulate titanium oxide, zinc oxide, fine and ultrafine particulate zinc oxide, aluminum oxide, silica, fumed silica (ultrafine particulate anhydrous silicic acid), mica titanium oxide, ultrafine particulate titanium oxide, and the like, Inorganic powders such as fish scale foils, boron nitride, photochromic pigments, synthetic fluorophlogopite, microparticle composite powders, inorganic powders of various sizes and shapes such as gold and aluminum, and powders hydrophobized or hydrophilized by treating them with various surface-treating agents such as silicone such as hydrogen-containing silicone and cyclic hydrogen-containing silicone, or other silanes or titanium coupling agents; examples of the inorganic particles include organic powders and surface-treated powders having various sizes and shapes such as starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, polyester powder, benzoguanamine resin powder, polyethylene terephthalate/polymethyl methacrylate laminated powder, polyethylene terephthalate/aluminum/epoxy laminated powder, and the like, polyurethane powder, silicone powder, teflon (registered trademark) powder, and organic-inorganic composite powders. The inorganic salts are preferably sodium chloride-containing salts such as table salt, raw salt (salt), rock salt, sea salt, and natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride and ammonium chloride; sodium sulfate, aluminum sulfate/potassium sulfate (alum), aluminum sulfate/ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, ferric sulfate, copper sulfate; sodium phosphates such as 1Na/2Na/3Na phosphate, potassium phosphates, calcium phosphates, and magnesium phosphates.

As the ultraviolet absorber, preferable examples include benzoic acid-based ultraviolet absorbers such as p-aminobenzoic acid, monoglyceride of p-aminobenzoic acid, ethyl N, N-dipropoxy-p-aminobenzoate, ethyl N, N-diethoxy-p-aminobenzoate, ethyl N, N-dimethyl-p-aminobenzoate, butyl N, N-dimethyl-p-aminobenzoate, ethyl N, N-dimethyl-p-aminobenzoate, and the like; anthranilic acid-based ultraviolet absorbers such as homomenthyl-N-acetyl anthranilate; salicylic acid-based ultraviolet absorbers such as salicylic acid and sodium salts thereof, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, and phenyl p-isopropoxide salicylate; octyl cinnamate, ethyl 4-isopropyl cinnamate, methyl 2, 5-diisopropyl cinnamate, ethyl 2, 4-diisopropyl cinnamate, methyl 2, 4-diisopropyl cinnamate, propyl p-methoxycinnamate, isopropyl p-methoxycinnamate, isoamyl p-methoxycinnamate, cinnamic acid-based ultraviolet absorbers such as 2-ethylhexyl p-methoxycinnamate (octyl p-methoxycinnamate), 2-ethoxyethyl p-methoxycinnamate (cinoxate), cyclohexyl p-methoxycinnamate, ethyl α -cyano- β -phenylcinnamate, 2-ethylhexyl α -cyano- β -phenylcinnamate (Octocrylene), glyceryl mono-2-ethylhexanoyl-di-p-methoxycinnamate, ferulic acid and derivatives thereof; 2, 4-dihydroxybenzophenone, 2 '-dihydroxy-4-methoxybenzophenone, 2' -dihydroxy-4, 4 '-dimethoxybenzophenone, 2', benzophenone-based ultraviolet absorbers such as 4, 4 ' -tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone (benzophenone-3), 2-hydroxy-4-methoxy-4 ' -methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4 ' -phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octyloxybenzophenone, and 4-hydroxy-3-carboxybenzophenone; 3- (4' -methylbenzylidene) -d, l-camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2, 2' -hydroxy-5-methylphenylbenzotriazole; 2- (2 '-hydroxy-5' -tert-octylphenyl) benzotriazole; 2- (2 '-hydroxy-5' -methylphenylbenzotriazole, dibenzalacazine, dimethoxybenzoylmethane (ジアニソイルメタン), 5- (3, 3-dimethyl-2-norbornylene) -3-pentan-2-one, dibenzoylmethane derivatives such as 4-tert-butylmethoxydibenzoylmethane, octyltriazone, urocanic acid derivatives such as urocanic acid and ethyl urocanic acid, hydantoin derivatives such as 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, 1- (3, 4-dimethoxyphenyl) -4, 4-dimethyl-1, 3-pentanedione, 2-ethylhexyl dimethoxybenzylidenedioxoimidazolidinepropionate, and the like, and mixtures thereof, Phenyl benzimidazole sulfonic acid, p-xylylene dicamphor sulfonic acid, cresol trozole trisiloxane, methyl anthranilate, rutin and derivatives thereof, and oryzanol and derivatives thereof.

Preferred examples of the vitamins and derivatives thereof include retinol, retinol acetate, retinol palmitate, and other vitamins a; nicotinic acids such as thiamine hydrochloride, thiamine sulfate, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dicaprylate, pyridoxine dipalmitate, flavin adenine dinucleotide, cyanocobalamin, folic acid, nicotinamide/benzyl nicotinate, and group B vitamins such as choline; ascorbic acids and salts thereof such as sodium ascorbate; vitamin D; vitamin E compounds such as alpha, beta, gamma, delta-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphate ester salts such as sodium ascorbyl phosphate and magnesium ascorbyl phosphate, ascorbic acid fatty acid esters such as tetraisopalmitate ascorbate/ascorbyl stearate/ascorbyl palmitate/ascorbyl dipalmitate, ascorbyl ethers such as ascorbyl ethyl ether, ascorbyl glucosides such as ascorbyl-2-glucoside, and ascorbic acid derivatives such as fatty acid esters thereof and ascorbyl tocopheryl phosphate; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol linoleate, tocopherol ferulate, and tocopherol phosphate, tocotrienol, and other various vitamin derivatives.

Preferred examples of the anti-inflammatory agent/anti-inflammatory agent include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphenhydramine hydrochloride (salt ジフェドラミン), and chlorphenamine maleate; peach leaf extract, folium Artemisiae Argyi extract, etc. The hair-growth agent/blood circulation promoter/stimulant is preferably selected from plant extracts/tinctures such as swertia japonica Makino extract, capsicum tincture, ginger extract, cantharis tincture, etc.; capsaicin, vanillylnonanoate (ノニル acid ワニリルアミド), zingerone, ichthammol, tannic acid, borneol, cyclanoate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthine, gamma-oryzanol, cepharanthine, vitamin E, and derivatives such as tocopherol nicotinate/tocopherol acetate, gamma-oryzanol, nicotinic acid and derivatives such as nicotinamide/benzyl nicotinate/inositol hexanicotinate, nicotinol, allantoin, photosensitizer 301, photosensitizer 401, carpronium chloride, pentadecaonoglyceride, flavanonol derivatives, stigmasterol or stigmastanol and its glycoside, minoxidil. Preferred hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone, and the like. Other agents such as anti-wrinkle agents, anti-aging agents, tightening agents, cold-feeling agents, warm-feeling agents, wound-repair promoters, irritation-relieving agents, analgesics, cell activators and the like include retinoids, tocopherol retinoic acid esters; derivatives such as lactic acid, glycolic acid, gluconic acid, tartaric acid, salicylic acid and glycosides/esters thereof, and α -or β -hydroxy acids such as hydroxydecanoic acid, long-chain α -hydroxy fatty acid, and long-chain α -hydroxy fatty acid cholesteryl ester, and derivatives thereof; gamma-aminobutyric acid, gamma-amino-beta-hydroxytyrosic acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine and the like and derivatives thereof; antioxidant/active oxygen scavenger such as coenzyme Q10, carotene, lycopene, astaxanthin, lutein, alpha-lipoic acid, platinum nanocolloid, and fullerene; catechins; flavonoids such as quercetin; isoflavones; gallic acid and ester sugar derivatives; polyphenols such as tannin, sesamin, procyanidin, chlorogenic acid, and apple polyphenol; rutin and glycoside derivatives; derivatives such as hesperidin and glycoside; lignan glycosides; glabridin, glabrene, liquiritin, isoliquiritin, etc.; lactoferrin; shogaol, gingerol; perfume materials such as menthol, camphor, cedrol, etc., and derivatives thereof; capsaicin, vanillin, and the like and derivatives; insect repellents such as diethyltoluamide; a complex of a physiologically active substance and a cyclodextrin.

Preferred examples of the plant/animal/microorganism extracts include iris extract, angelica keiskei extract, hiba extract, asparagus extract, avocado extract, dichroa febrifuga extract, almond extract, marshmallow extract, arnica extract, aloe extract, apricot kernel extract, ginkgo leaf extract, artemisia capillaris extract, fennel extract, turmeric extract, oolong tea extract, bearberry leaf extract, camptotheca acuminata extract, echinacea leaf extract, plectranthus asiatica extract, scutellaria baicalensis extract, phellodendron extract, coptis chinensis extract, barley extract, ginseng extract, forsythia suspense extract, sessile wild sesame extract, formononetin extract, cress extract, orange extract, seawater dried product, seaweed extract, persimmon leaf extract, pyracantha fortuneana extract, hydrolyzed elastin, aloe extract, apricot kernel extract, ginkgo leaf extract, artemisia capillaris extract, fennel extract, turmeric extract, pennywort extract, echinacea extract, apricot kernel extract, ginkgo extract, marine extract, ginkgo extract, hydrolyzed wheat flour, hydrolyzed silk protein, kudzu root extract, chamomile extract, oil-soluble chamomile extract, carrot extract, mugwort extract, avena sativa extract, roselle extract, licorice extract, oil-soluble licorice extract, kiwi extract, chia extract (キオウエキス), jelly fungus extract, cinchona extract, cucumber extract, tung leaf extract, guanosine, guava extract, sophora flavescens extract (クジンエキス), gardenia extract, phyllostachys pubescens extract, sophora flavescens extract (クララエキス), walnut extract, chestnut extract, grapefruit extract, clematis chinensis extract, black rice extract, muscovado extract, black vinegar, chlorella extract, mulberry extract, gentiana lutea root extract, geranium extract, black tea extract, yeast extract, aloe extract, black tea extract, aloe extract, and other extract, extract, Magnolia bark extract, coffee extract, burdock extract, rice fermented extract, rice bran fermented extract, rice germ oil, comfrey extract, collagen, blueberry extract, asarum extract, bupleurum extract, umbilical cord extract, crocus sativus extract, sage extract, lycopodium extract, bamboo extract, hawthorn extract, silkworm excrement extract, Japanese pepper extract, shiitake mushroom extract, rehmannia extract, Japanese sage root extract, perilla extract, linden extract, mosquitos extract, twinleaf bean extract, peony extract, ginger extract, calamus extract, white birch extract, tremella extract, horsetail extract, stevia rebaudiana fermented product, Chinese tamarind extract, hedera extract, American hawthorn extract, American elderberry extract, milfoil extract, Chinese fevervine extract, Chinese feverfew extract, etc, Mentha haplocalyx extract, sage extract, mallow extract, cnidium officinale extract, swertia japonica extract, mulberry bark extract, rhubarb extract, soybean extract, jujube extract, thyme extract, dandelion extract, lichens extract, tea extract, clove extract, citronella extract, dried orange peel extract, tea tree oil, sweet tea extract, capsicum extract, angelica extract, calendula extract, peach kernel extract, orange peel extract (トウヒエキス), houttuynia extract (ドクダミエキス), tomato extract, natto extract, carrot extract, garlic extract, rose extract, hibiscus extract, ophiopogon root extract, lotus extract, parsley extract, birch extract, honey, witch hazel extract, sage extract, caraway extract, bisabolol, patchouli extract, bisabolol, patchouli extract, and mixtures thereof, Japanese cypress extract, bifidobacterium extract, loquat extract, coltsfoot stem extract, poria cocos extract, ruscus aculeatus extract, grape seed extract, propolis, luffa extract, safflower extract, mint extract, linden extract, peony extract, hop extract, rose extract, pine extract, aesculus hippocastanum extract, osbeckia extract, soapberry extract, melissa extract, nemacystus extract, peach extract, cornflower extract, eucalyptus extract, saxifrage extract, Japanese pomelo extract, lily extract, coix seed extract, artemisia extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, Aspalathus linearis extract, lychee extract (レイシエキス), lettuce extract, black bean extract, etc, Lemon extract, forsythia extract, astragalus sinicus extract, rose extract, rosemary extract, roman chamomile extract, royal jelly extract, sanguisorba extract and the like.

Examples of the antipruritic agent include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance P inhibitor, and the like. Examples of the exfoliating/dissolving agent include salicylic acid, sulfur, resorcinol, selenium sulfide, pyridoxine, and the like. Examples of the antiperspirant include aluminum hydroxychloride, aluminum chloride, zinc oxide, and zinc p-phenolsulfonate. Examples of the laminate roll include menthol and methyl salicylate. Examples of the astringent include citric acid, tartaric acid, lactic acid, aluminum/potassium sulfate, and tannic acid. Examples of the enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, and protease. Preferred examples of the nucleic acids include ribonucleic acid and salts thereof, deoxyribonucleic acid and salts thereof, and disodium adenosine triphosphate.

Preferred examples of the perfume include acetocedrene, amyl cinnamaldehyde, allyl amyl glycolate, β -ionone, ambroxone, isobutyl quinoline, iris oil, irone, indole, ylang-ylang oil, undecylenic aldehyde, γ -undecalactone, estragole, eugenol, oak moss, bisabolol, orange oil, eugenol, nerolin, galaxolide (ガラクソリッド), carvacrol, L-carvone, camphor, gannong (キャノン), carrot seed oil, clove oil, methyl cinnamate, geraniol, geranonitrile, isobornyl acetate, geranyl acetate, dimethylbenzyl methyl acetate, styryl acetate, cedryl acetate, terpinyl acetate (テルピネル), p-tert-butylcyclohexyl acetate, bergenyl acetate, benzyl acetate, eugenyl acetate, isovaleryl acetate, irilone acetate, irisone acetate, and carvone acetate, Linalyl acetate, isoamyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamen aldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromyrcenol, jasmonate, jasmone, cis-jasmone, citral, citronellol (citronellol), citronellal, cassia oil, 1, 8-cineole, cinnamaldehyde, styrol, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascone, damascenone, thymol, tuberose oil, decanal, decalactone, terpineol, gamma-terpinene, ligustral, nerol, nonanal, 2, 6-nonadienol, nonalactone, patchouli alcohol, cymene absolute, vanillin, basil oil, patchouli oil, hydroxycitronellal, alpha-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, orange leaf oil, hexyl cinnamaldehyde, santalol, citronellal, citronellol, myrtillin, geraniol, myrtillin, myrtilon, Cis-3-hexenol, peru balsam, vetiver oil, vetiverol, peppermint oil, pepper oil, piperonal, bergamot oil, benzyl benzoate, borneol, myrrh resin (myrrh resinoid), muscone, methyl nonyl acetaldehyde, gamma-methyl ionone, menthol, L-menthone, eucalyptus oil, beta-ionone, pear berry oil, lavender oil, D-limonene, linalool, lyral, lilial, lemon oil, rose absolute, rose ether, rose oil, rosemary oil, various essential oils and other synthetic and natural perfumes and various blend perfumes.

Preferred examples of the pigment, colorant, dye and pigment include brown color No. 201, Black color No. 401, purple color No. 201, purple color No. 401, blue color No. 1, blue color No. 2, blue color No. 201, blue color No. 202, blue color No. 203, blue color No. 204, blue color No. 205, blue color No. 404, green color No. 201, green color No. 202, green color No. 204, green color No. 205, green color No. 401, green color No. 402, Red color No. 102, Red color No. 104-1, Red color No. 105-1, Red color No. 106, Red color No. 2, Red color No. 201, Red color No. 202, Red color No. 203, Red color No. 204, Red color No. 205, Red color No. 206, Red No. 207, Red No. 208, Red No. 213, Red No. 214, Red No. 215, Red 218, Red No. 219, Red No. 220, Red No. 221, Red No. 223, Red No. 225, Red No. 226, Red No. 227, Legal pigments such as Red 228, Red 230-1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503, Red 504, Red 505, Red 506, orange 201, orange 203, orange 204, orange 205, orange 206, orange 207, orange 401, orange 402, orange 403, yellow 201, yellow 202-1, yellow 202-2, yellow 203, yellow 204, yellow 205, yellow 4, yellow 401, yellow 402, yellow 403-1, yellow 404, yellow 405, yellow 406, yellow 407, yellow 5, etc.; acid red 14 and other acid dyes; basic dyes such as ochre Brown (Arianor Sienna Brown), bright Red (Arianor Madder Red), Steel Blue (Arianor Steel Blue), grass Yellow (Arianor strong Yellow); nitro dyes such as HC yellow 2, HC yellow 5, HC red 3, 4-hydroxypropylamino-3-nitrophenol, N' -bis (2-hydroxyethyl) -2-nitro-p-phenylenediamine, HC blue 2, and basic blue 26; disperse dyes; inorganic white pigments such as titanium dioxide and zinc oxide; inorganic red pigments such as iron oxide (red iron oxide) and iron titanate; inorganic brown pigments such as gamma-iron oxide; inorganic yellow pigments such as yellow iron oxide and yellow soil; inorganic black pigments such as iron oxide black and low-valent titanium oxide; inorganic violet pigments such as manganese violet and cobalt violet; inorganic green pigments such as chromium oxide, chromium hydroxide, and cobalt titanate; ultramarine blue pigments, berlin blue pigments, and the like; titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, colored titanium oxide-coated mica, bismuth oxychloride, fish scale foil, and other pearlescent pigments; metal powder pigments such as aluminum powder, copper powder, and gold; surface treated inorganic and metallic powder pigments; organic pigments such as zirconium, barium or aluminum lakes such as red 201, red 202, red 204, red 205, red 220, red 226, red 228, red 405, orange 203, orange 204, yellow 205, yellow 401, blue 404, red 3, red 104, red 106, red 227, red 230, red 401, red 505, orange 205, yellow 4, yellow 5, yellow 202, yellow 203, green 3, blue 1; a surface-treated organic pigment; anthraquinones such as astaxanthin and alizarin, natural pigments/dyes such as anthocyanins, β -carotene, pigments (カテナール, carthenal), capsanthin, chalcones, carthamin, quercetin, crocin, chlorophyll, curcumin, cochineal, naphthoquinones such as shikonin, bixin, flavonoids, β -cyanidin (ベタシアニジン), henna, hemoglobin, lycopene, riboflavin, and rutin; oxidation dye intermediates and couplers such as p-phenylenediamine, toluene-2, 5-diamine, o-, m-or p-aminophenol, m-phenylenediamine, 5-amino-2-methylphenol, resorcinol, 1-naphthol, 2, 6-diaminopyridine and the like, and salts thereof; auto-oxidation dyes such as indoline; dihydroxyacetone.

The water is preferably hard water, soft water, natural water, deep seawater, electrolytic alkali ion water, electrolytic acid ion water, or an ion cluster, in addition to normal water and purified water.

In addition, known Cosmetic ingredients, pharmaceutical ingredients, food ingredients, and The like such as ingredients described in The standards of Cosmetic raw materials, specifications of ingredients for Cosmetic varieties, The display name table of ingredients of The Japanese Association of cosmetics industry, The INCI Dictionary (The International Cosmetic Ingredient Dictionary and Handbook), The specifications of raw materials for products outside The Japanese medical department, The Japanese pharmacopoeia, specifications of pharmaceutical additives, ingredients described in food additives official books, and The like, and The International patent Classification IPC belonging to The classifications A61K7 and A61K8 in Japanese and various foreign patent publications and patent laid-open publications (including The official gazettes and The re-official tables) may be contained in known combinations and mixing ratios/mixing amounts.

Examples of the type of cosmetic material of the present invention include hair cosmetic materials, foundation cosmetic materials, cosmetic materials, aromatic cosmetic materials, body cosmetic materials, skin external preparations such as ointments, and the like. From the viewpoint of exhibiting the effects of the present invention, a hair cosmetic material and a base cosmetic material can be particularly preferably used. The cosmetic material of the present invention can be produced by a conventional method.

To describe the types of the cosmetic materials of the present invention in more detail, preferred examples of the hair cosmetic materials include shampoos such as oil shampoo, cream shampoo, conditioning shampoo, anti-dandruff shampoo, hair dye shampoo, and conditioner-integrated shampoo; hair conditioners such as hair conditioners, hair masks, hair sprays and the like; hair styling products such as hair style (hair form), mousse, hair spray, hair wax, hair styling gel, hair cream, water hair rinse, setting lotion, hair rinse, and hair oil (チック); a coloring emulsion, a hair tonic, a hair lotion, a styling mousse, a bifurcation restorer, a hair oil, a permanent wave agent, an oxidative hair dye, a hair bleach, a pre-hair dyeing conditioner, a post-hair dyeing conditioner, a pre-hair waving conditioner, a post-hair waving conditioner, a hair restorer, a hair tonic.

Preferred examples of the base cosmetic material include lotions such as a smoothing lotion, a astringent lotion, a cleansing lotion, and a multi-layer lotion; lotions such as skin lotion, moisturizing lotion, milky lotion, moisturizing lotion, skin cream, skin moisturizer, moisturizing emulsion, massage emulsion, makeup remover emulsion, skin care emulsion, Sun screen (Sun protector), UV screen, Sun screen, makeup cream, cutin smoother, elbow lotion, hand lotion, body lotion, and the like; moisturizing creams, nourishing creams (non-emulsifying cream), vanishing creams, moisturizing creams, night creams, massage creams, cleansing creams, cosmetic creams, foundation creams, make-up front creams, sun-screening creams (sun cream), depilatory creams, deodorant creams, shaving creams, cutin softening creams, and the like; moisturizing gels and the like; essence such as moisturizing essence, whitening essence, ultraviolet-proof essence and the like; liposome cosmetics such as liposome cosmetic liquid and liposome cosmetic water; mask/face mask such as stripping type mask, powder dispersing mask, washing mask, essential oil mask, cleaning mask, etc.; cleaning materials such as cleaning foam, cleaning cream, cleansing milk, makeup removing milk, cleaning gel, cleaning oil, cleaning facial mask, cleaning flour, cleaning powder and the like; soap such as cosmetic soap, transparent soap, medicinal soap, liquid soap, shaving soap, synthetic cosmetic soap, etc.

As cosmetic makeup materials, preferred are facial powder/face powder, foundation, lipstick, lip gloss, popliteal, eyeliner, mascara, eye shadow, eyebrow pencil, nail polish remover, and nail care materials.

Preferred examples of the aromatic cosmetic material include perfume, aroma, essence, eau de toilette, cologne, solid perfume, aromatic powder, soap, body lotion, and bath oil.

Preferred examples of the body cosmetic material include body cleansers such as body shampoos, deodorant lotions, deodorant powders, deodorant sprays, deodorant sticks, insect repellents (insect repellents) such as decolorants, depilatories/depilatories, bath agents, and mosquito repellents.

The skin external preparation can be used in the form of an ointment, a patch, an emulsion, a liniment, a liquid coating agent, or the like. In addition, it can be used as an oral cavity cosmetic material such as toothpaste and mouthwash.

The formulation of the cosmetic material or the external preparation for skin of the present invention is preferably an emulsion type cosmetic material such as oil-in-water (O/W) type, water-in-oil (W/O) type, W/O/W type, O/W/O type, oil type cosmetic material, solid cosmetic material, liquid cosmetic material, paste cosmetic material, stick cosmetic material, volatile oil type cosmetic material, powder cosmetic material, gel type cosmetic material, cream cosmetic material, emulsion polymer type cosmetic material, sheet cosmetic material, mist cosmetic material, spray type cosmetic material, or the like.

Examples

The present invention will be described in more detail with reference to the following examples, but the present invention is not limited to these examples.

Preparation of Fullerene-dissolved oil of component (A)

In the presence of fullerene (C)₆₀、C₇₀Mixture) 0.3g of toluene was added to 300g of toluene, and the mixture was dissolved with stirring at room temperature for 2 hours, followed by filtration through a 0.2 μm PTFE membrane filter. 99.7g of each oil agent having the composition shown in Table 1 was added to the obtained filtrate, and then toluene was distilled off under reduced pressure by a rotary evaporator (80 ℃ C., 0.1MPa, 2 hours), followed by filtration through a 1 μm PTFE membrane filter to obtain a fullerene-dissolved oil as component (A) of the present invention. The fullerene dissolved oil obtained as described above was a brown liquid. Analysis of the obtained fullerene-dissolved oil by HPLC under the following conditions₆₀The results are shown in the lower column of Table 1.

< conditions for fullerene analysis by HPLC >

A detector: ultraviolet absorptiometer 340 nm.

A chromatographic column: inertsil ODS-24.6X 250mm, GL science Inc. (GL サイエンス, strain).

Temperature of the column: at 40 ℃.

Mobile phase: methanol (420 mL) was measured and toluene was added thereto to yield 1000 mL.

Table 1% by weight

	Preparation example 1	Preparation example 2	Preparation example 3	Preparation example 4	Preparation example 5
						Fullerene (C)60、C70Mixture)	0.3	0.3	0.3	0.3	0.3
(caprylic/capric) triglyceride	19.5	99.5		19.7
						Cetyl ethylhexanoate ester	80		99.5	80
Squalane					99.70
						Gamma-docosanolides	0.2	0.2	0.2
Fullerene C60Concentration of	0.15％	0.15％	0.14％	0.03％	0.03％

According to the results of Table 1, fullerene C in the fullerene-dissolved oil obtained by the foregoing production method₆₀The content of (B) is 0.03 to 0.15 wt%. It is found that the oil solution to which γ -docosanolide is added has a particularly high fullerene content.

Preparation and evaluation of the cosmetic composition of the present invention

The components were uniformly mixed with stirring according to the compositions shown in table 2 to prepare cosmetic compositions of the present invention containing components (a) to (E) (examples 1 to 6). Similarly, cosmetic compositions (reference examples 1 to 6) were prepared according to the compositions shown in Table 3. The appearance of the obtained cosmetic composition and the results of evaluating whether a bicontinuous structure was formed and the storage stability by the following methods are shown in the lower columns of tables 2 and 3.

< confirmation of bicontinuous Structure >

20g of the cosmetic composition was put into a glass screw bottle, and 0.1g of a water-soluble coloring matter (purple 401) having a concentration of 0.01% was added to the bottle to prepare an aqueous solution. Similarly, 0.01% oil-soluble pigment (No. 225 red) was added to another vessel together with 0.1g squalane liquid. The appearance of the composition containing these colorants was visually observed, and when the composition was uniformly colored in its entirety and had transparency in each of the water-soluble and oil-soluble colorants, it was judged that a bicontinuous structure was formed. On the other hand, when neither or both of the coloring matters is uniformly colored or turbid, it is judged that no coloring matter is formed.

O: any of the pigments was uniformly colored and had transparency.

X: in either or both pigments, there is no uniform coloration or liquid cloudiness.

< storage stability of cosmetic composition >

The obtained cosmetic composition was subjected to a storage stability test at 50 ℃/1 month, and evaluated according to the following evaluation criteria.

O: the appearance was not changed from the initial one after storage.

X: after storage, the mixture appeared white and turbid, or separated into two phases, compared with the initial one.

Table 2% by weight

Table 3% by weight

As a result of tables 2 and 3, the cosmetic compositions of examples 1 to 6 and reference examples 1 to 6 can easily disperse fullerene. Among them, the cosmetic compositions of examples 1 to 6 having a bicontinuous structure had transparent appearance and excellent storage stability. On the other hand, the cosmetic compositions of reference examples 1 to 6, in which no bicontinuous structure was formed, showed cloudiness in appearance from the initial stage and poor storage stability.

Preparation and evaluation of aqueous Dispersion containing Fullerene

Aqueous dispersions of fullerene-containing cosmetic compositions of examples 1 to 6 and reference examples 1 to 6 were prepared according to the compositions shown in tables 4 and 5. The preparation method comprises the following steps: 49g of water in which methylparaben had been dissolved in advance was added to a 100mL beaker, and 1g of each cosmetic composition was slowly added while stirring with a stirrer (600rpm), and the mixture was stirred at room temperature for 5 minutes. The obtained aqueous dispersion was evaluated for initial dispersibility, transparency/transmittance, and dispersion stability by the following methods, and the results are shown in the following columns of tables 4 and 5.

< initial dispersibility of aqueous Dispersion >

The obtained aqueous dispersion was visually observed for the dispersion state immediately after the preparation, and the initial dispersibility was evaluated according to the following evaluation criteria.

O: are uniformly dispersed.

X: not uniformly dispersed.

< transparency/transmittance of aqueous dispersion >

The obtained aqueous dispersion was placed in a glass bottle having a diameter of 3.5cm, and the appearance was visually observed from the lateral direction, and the transparency was evaluated according to the following evaluation criteria. The transmittance of the aqueous dispersion was measured using a spectrophotometer (cuvette thickness 1cm, wavelength 600 nm).

O: the liquid can be seen through the back.

X: the liquid cannot be seen through the back.

< Dispersion stability of aqueous Dispersion >

The resulting aqueous dispersion was subjected to a storage stability test at 50 ℃/1 month, and the dispersion stability was evaluated according to the following evaluation criteria.

O: it is also uniformly dispersed after storage.

X: they were not uniformly dispersed or precipitated after storage.

Table 4% by weight

Table 5% by weight

From the results shown in tables 4 and 5, the aqueous dispersion prepared using the cosmetic composition of the present invention (forming a bicontinuous structure) enables fullerene to be easily dispersed in water, and is excellent in initial dispersibility, transparency and dispersion stability. On the other hand, the aqueous dispersion prepared using the cosmetic composition of the reference example (without forming a bicontinuous structure) tends to disperse fullerene in water, but it is not dispersible from the initial stage, or is not sufficiently transparent and dispersion stable even if it is dispersible.

The cosmetic composition of the present invention was used to prepare a cosmetic described below. The obtained cosmetic material can be prepared by simply and stably mixing fullerene, and has excellent moisture retention, improved hair hole enlargement, improved hair breakage, and elasticity (bounce and resilience).

Example 13 Hair spray

(preparation method)

Separately weighing A, B parts, mixing, and mixing the two preparations.

EXAMPLE 14 Hair conditioner

(preparation method)

The A part which had been mixed and dissolved in advance was added to the B part, and the mixture was uniformly mixed at about 80 ℃ (D part). Heating the other part C to 80 deg.C to homogenize. Gradually add the mixture to the mixture in section C while stirring, uniformly mix the mixture, and cool the mixture to about 50 ℃.

Example 15 Hair conditioner

(preparation method)

The A part which had been mixed and dissolved in advance was added to the B part, and the mixture was uniformly mixed at about 80 ℃ (D part). Heating the other part C to 80 deg.C to homogenize. Gradually add the mixture to the mixture in section C while stirring, uniformly mix the mixture, and cool the mixture to about 50 ℃.

EXAMPLE 16 Hair conditioner

(preparation method)

The A part which had been mixed and dissolved in advance was added to the B part, and the mixture was uniformly mixed at about 80 ℃ (E part). Heating the other part C to 80 deg.C to homogenize. Gradually add the mixture to the mixture in section C while stirring, mix the mixture uniformly, and cool the mixture to about 50 ℃. Further, part D was added and mixed uniformly.

EXAMPLE 17 Hair conditioner

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. The part A was put into another vessel and heated to dissolve it. Slowly adding part B into part A, mixing, and cooling.

EXAMPLE 18 Care agent

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. The part A was put into another vessel and heated to dissolve it. Slowly adding part B into part A, mixing, and cooling.

EXAMPLE 19 Care agent

(preparation method)

The part A and part B, which were previously mixed and dissolved, were heated to about 80 ℃ and mixed uniformly (part D). Heating the other part C to about 60 deg.C to homogenize. Gradually add the mixture to the mixture in section D while stirring, mix the mixture uniformly, and cool the mixture to about 50 ℃.

Example 20 shampoo

(preparation method)

The parts a and B, which were previously mixed and dissolved, were uniformly mixed at about 80 ℃ (part E). Heating the other part C to about 60 deg.C to homogenize. Gradually add the mixture to the mixture in section E while stirring, mix the mixture uniformly, and cool the mixture to about 50 ℃. Then add part D and mix well.

EXAMPLE 21 shampoo for dandruff removal

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. Placing part A in another container, and heating to dissolve part A. Part B was added slowly to part A, mixed homogeneously, and part C was added at about 60 ℃.

EXAMPLE 22 shampoo

(preparation method)

The parts a and B, which were previously mixed and dissolved, were uniformly mixed at about 80 ℃ (part E). Heating the other part C to about 60 deg.C to homogenize. Gradually add the mixture to the mixture in section E while stirring, mix the mixture uniformly, and cool the mixture to about 50 ℃. Then add part D and mix well.

Example 23 silicon-free shampoo

(preparation method)

The parts a and B, which were previously mixed and dissolved, were uniformly mixed at about 80 ℃ (part E). Heating the other part C to about 60 deg.C to homogenize. Gradually add the mixture to the mixture in section E while stirring, mix the mixture uniformly, and cool the mixture to about 50 ℃. Then add part D and mix well.

EXAMPLE 24 shampoo

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. Placing part A in another container, and heating to dissolve part A. Part B was added slowly to part A, mixed homogeneously, and part C was added at about 60 ℃.

Example 25 shampoo

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. Placing part A in another container, and heating to dissolve part A. Part B was added slowly to part A, mixed homogeneously, and part C was added at about 60 ℃.

Example 26 silicon-free shampoo

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. Placing part A in another container, and heating to dissolve part A. Part B was added slowly to part A, mixed homogeneously, and part C was added at about 60 ℃.

Example 27 shampoo

(preparation method)

Part B was heated to about 80 ℃ to dissolve it uniformly. Placing part A in another container, and heating to dissolve part A. Part B was added slowly to part A, mixed homogeneously, and part C was added at about 60 ℃.

EXAMPLE 28 leave-on conditioner

(preparation method)

The homogeneously mixed part A was added to part B and the temperature was raised to about 80 ℃ to dissolve the component (part E). In another vessel, part D was warmed to about 80 ℃ to dissolve it. Gradually adding the mixture to the mixture in section E while stirring, uniformly mixing, and rapidly cooling (section F). Part C was added to part F at about 40 ℃ to homogenize the mixture.

Example 29 Hair wax

(preparation method)

The temperature of part A and part B was raised to about 80 ℃ respectively, and the components were uniformly mixed. Gradually adding the mixture into part A while stirring, uniformly mixing, and cooling.

Example 30 Hair wax

(preparation method)

The A part which had been mixed and dissolved in advance was added to the B part, and the mixture was uniformly mixed at about 80 ℃ (E part). Heating the other part C to about 60 deg.C to homogenize. Gradually add the mixture to the mixture in section E while stirring, mix the mixture uniformly, and cool the mixture to about 50 ℃. Then add part D and mix well.

Example 31 mousse

(preparation method)

Mixing the above components, mixing with matrix: LPG 92: 8 the obtained substrate and LPG were mixed to make a jet mousse.

Example 32 Hair cream

(preparation method)

Mix part A at 80 ℃. The temperature of part C was raised to 80 ℃ and the mixture was added to part A to emulsify the mixture (part D). After cooling to 50 ℃, part B was added to homogenize the mixture.

Example 33 leave-on conditioner

(preparation method)

The previously mixed and dissolved part A was added to part B, and the temperature was raised to about 80 ℃ to dissolve it (part E). In another vessel, part D was warmed to about 80 ℃ to homogenize it. Gradually adding the mixture to the mixture in section E while stirring, uniformly mixing, and rapidly cooling (section F). The C portions were added to the F portions at about 40 ℃ to homogenize the mixture.

Example 34 Hair oil

(preparation method)

Heating to dissolve all components, and mixing.

Example 35 whitening lotion

(preparation method)

Mixing the parts B, and adjusting the viscosity of the liquid. The temperature of part A was raised to 50 ℃ and the mixture was gradually added to part B while stirring. Then, the pre-mixed part C and part D are added to form a uniform liquid.

Example 36 whitening lotion

(preparation method)

The components A were mixed and gradually added to the component B under stirring at about 50 ℃ to prepare a dispersion. Then, the pre-mixed part C and part D are added to form a uniform liquid.

Example 37 moisturizing lotion

(preparation method)

The components A were mixed and gradually added to the component B with stirring to prepare a dispersion. And then added to the previously mixed part C to form a uniform liquid.

Example 38 moisturizing lotion

(preparation method)

The component A was mixed and slowly added to the component B with stirring to prepare a dispersion. And then added to the previously mixed part C to form a uniform liquid.

Example 39 gel cosmetic Water

(preparation method)

Part A was heated to about 70 ℃ to disperse it uniformly. Mix part C, stir thoroughly, heat to about 70 ℃ after it is homogeneous. Part B was stirred with a propeller to prepare a dispersion. Part C was added to part A, stirred at about 70 ℃ using a homomixer, cooled to about 40 ℃, and the mixture of part B was added.

EXAMPLE 40 clear gel

(preparation method)

Part A was stirred with a propeller to prepare a dispersion. When the component C is mixed, a viscous liquid is obtained. Mixing the part B to obtain a uniform liquid. Part A and part B are added to part C to make them uniform.

Example 41 moisturizing emulsion

(preparation method)

The A part, the B part and the E part were mixed, and the temperature was raised to about 70 ℃ to dissolve and disperse the components uniformly. The dispersion was prepared by mixing part C with a propeller (room temperature). And mixing and stirring the D parts to obtain viscous liquid. While stirring part A with a homogenizing disperser, part B is added, part E is added, and emulsification is carried out. Cooling, adding C, D parts at 50 deg.C, stirring, and cooling to 40 deg.C.

Example 42UV emulsion

(preparation method)

The A part, the B part and the D part were mixed, and the temperature was raised to about 70 ℃ to uniformly dissolve and disperse the components. Mixing and stirring the part C to obtain viscous liquid. Adding part B while stirring part A with a homomixer, adding part D, and emulsifying. Cooling, adding part C at about 50 deg.C, stirring, and cooling to about 40 deg.C.

Example 43UV emulsion

(preparation method)

The A part, the B part and the E part were mixed, and the temperature was raised to about 70 ℃ to uniformly dissolve and disperse the components. Mixing and stirring the part C to obtain viscous liquid. The dispersion was obtained by mixing the component D with propeller stirring. While stirring part A with a homogenizing disperser, part B is added, part E is added, and emulsification is carried out. Cooling, adding into part D and part F at about 50 deg.C, stirring, and cooling to about 40 deg.C.

Example 44 skin cream

(preparation method)

Part A was mixed and heated to about 70 ℃ to dissolve it uniformly. Mixing and stirring the part B to obtain viscous liquid. Mix part C, heat to about 70 ℃ to disperse it evenly. Mix part D, heat to about 70 ℃ to dissolve it uniformly. Part A was added to part C while stirring with a homogenizer, and part D was added to emulsify. Cooling, adding into part B at about 50 deg.C, stirring, and dissolving uniformly.

Example 45 skin cream

(preparation method)

Part A was heated to about 70 ℃ to dissolve it uniformly. The temperature of part C was raised to about 70 ℃ to disperse the part C. The dispersion was prepared by stirring well the D part with a propeller. Slowly adding part A into part C while stirring with a homomixer at about 70 deg.C, emulsifying, mixing uniformly, cooling to about 40 deg.C, adding parts B and D, and mixing uniformly.

Example 46 skin cream

(preparation method)

Part A was heated to about 70 ℃ to disperse it uniformly. Part B was heated to about 80 ℃ to dissolve it uniformly. The part C was sufficiently stirred to prepare a dispersion. While stirring part A with a homogenizing disperser, part B is added and dispersed (part E). And adding part D to part E while stirring. Stirred and cooled to about 40 ℃.

Example 47 scalp lotion

(preparation method)

The ingredients were measured separately and mixed uniformly. The dispersion was prepared by adding part A to part B. The mixture was further added while stirring the mixture in section C to homogenize the mixture.

Example 48 scalp lotion

(preparation method)

Part A was stirred with a propeller to prepare a dispersion. The components in the parts B and C are measured respectively and mixed uniformly. Part B was added to part A to make it uniform, and part C was added to make it uniform.

Example 49 body shampoo

(preparation method)

The A part was mixed with stirring by a propeller to prepare a dispersion. Measure part B, heat to about 80 deg.C, mix uniformly. While stirring, part B was cooled and part A was added at 40 ℃.

EXAMPLE 50 Hair spray

(preparation method)

Separately weighing A, B parts, mixing, and mixing the two preparations to obtain uniform mixture. Then the uniformly mixed part C is added to form liquid which is separated into two phases.

The details of the components described in the above-mentioned recipe by the product name are as follows.

Good Planglool-H: (phytosterol/isostearyl alcohol/cetyl alcohol/stearyl alcohol/behenyl alcohol) dimerized linoleate

Good Planglool-S: (phytosterol/isostearyl alcohol/cetyl alcohol/stearyl alcohol/behenyl alcohol) dimerized linoleate

Good Planglool-G: bis (behenyl alcohol/isostearyl alcohol/phytosterol) dioleyl dioleate

Good Planglool-DP: bis-diglycerol polyacyladipate 2

Good Planglool-ISS: phytostearic acid phytosterol ester

Good Plandogol-SUN: sunflower seed oil fatty acid phytosterol ester

Good Planglool-MAS: australia walnut oil fatty acid phytosterol ester

Good Plandogol-LG 1: di (phytosterol/octyldodecanol/behenyl) lauroyl glutamate

Good Plandogol-LG 2: di (phytosterol/octyldodecanol) lauroyl glutamate

Good Plandogol-LG 3: di (phytosterol/octyldodecanol/behenyl) lauroyl glutamate

Good Plandogol-LG 4: di (phytosterol/octyldodecanol/behenyl) lauroyl glutamate

Good LUSPLAN DD-IS: dioleyl dimer diisostearate

Good LUSPLAN PI-DA: di (isostearyl alcohol/phytosterol) dimer linoleate

Good LUSPLAN DD-DHR: dioleyl dimer hydrogenated rosin condensation product

Good LUSPLAN DD-DA 5: dioleyl dimer linoleate

Good LUSPLAN DD-DA 7: dioleyl dimer linoleate

Good LUSPLAN SR-DM 4: dimer linoleate, Tris (caprylic/capric) glyceride

Good LUSPLAN SR-DP 4: dioleyl dimer linoleate pentaerythritol tetraisostearate

Good Neocoole-Aqulio: diethoxydiol cyclohexane dicarboxylate

Good neocoole-Aqua: polyglyceryl-10 (eicosanedioic acid/tetradecanedioic acid) ester, glycerin

Good neocoole-AquaS: polyglyceryl-10 (eicosanedioic acid/tetradecanedioic acid) ester, glycerin

Good Neocoole-MP: methylpentanediol dipivalate

Good Neocoole-DE: diethylpentanediol dipivalate

Good Neocoole-IOP: ethyl hexyl palmitate

Good Neocoole-EHS: diethylhexylsebacate

Good Composite-PC: hydrogenated lecithin, cholesterol

Good phytompo-PP: hydrogenated lecithin, phytosterol

Good phytompo-C: hydrogenated lecithin, phytosterol, ceramide 2, ceramide 3, ceramide 6II

Good phytompo-C5: hydrogenated lecithin, phytosterol, ceramide 2, ceramide 3, ceramide 6II

Good phytompo-SP: hydrogenated lecithin, phytosterol, BG, Glycerol

Good LP 70H: hydrogenated lysolecithin (Japanese Kogyo Co., Ltd.)

Good Tremoist-TP: tremella polysaccharide

Good Tremoist-SL: aqueous solution of Tremella polysaccharide (1%)

Good YOFCO MAC: australia walnut oil fatty acid cholesterol ester

Good cationic NH: quaternary ammonium salt-33

Good erucic acid lactone DES: gamma-docosanolide, diethyl sebacate

Good erucic acid lactone MCT: gamma-docosanolide, tri (caprylic/capric) glycerides

Good nanometer repairing agent-CMC 5: ceramide 1, ceramide 2, ceramide 3, ceramide 5, ceramide 6, cholesterol, quaternary ammonium salt-33, and the like

Good NS-408: pentaerythritol Tetraethylcaproate

Good Bellpol L-50: PEG-50 lanolin

Example 51

The cosmetic composition of example 1 was confirmed to have an effect of suppressing hair discoloration.

(materials used, etc.)

Human hair: white hair (Japanese beauty Co., Ltd. (L.) ビューラックス)

Hair coloring concerns: vena bleaching and dyeing cream, Krispan perfect 14/45(KOLESTON PERRECT 14/45), Venapon perfect (Welloxon Perfect) (manufactured by cleaning company (P & G) above)

Preparation prepared from composition for removing fullerene from composition for cosmetic material of example 1

Preparation from the composition for cosmetic Material of example 1

(preparation of the preparation)

< preparation of preparation 1 of example 1 >

0.5g of the cosmetic composition of example 1 was dissolved in 49.5g of water to obtain preparation 1.

< preparation of preparation 2 in which fullerene was removed from example 1 >

0.5g of the composition obtained by removing fullerene from the cosmetic composition of example 1 was dissolved in 49.5g of water to obtain preparation 2.

(treatment method)

Bleaching and dyeing treatment

The bleaching and dyeing treatment is carried out twice on 3 white hairs.

Mixing the raw materials in a ratio of 1: 2, mixing the fenneling cream and the fennelone perfectly, and coating the mixture on the hair. After the application, the hair was left to stand for about 40 minutes, washed with hot water, and then washed twice.

Hair dyeing treatment

Mixing the raw materials in a ratio of 1: 2 after perfectly thorough mixing of krill 14/45 and vinapone, the mixture was applied to bleached and dyed hair tresses. After leaving for 30 minutes, the hair was washed and dried with a desiccator.

Destruction treatment

After washing the hair strand, drying it with a towel, spraying the preparation, completely drying it with a dryer, spraying water gently, and adding UVB (about 5 mW/cm)²) This was repeated as 1 time for 10 minutes to break the hair strand dyed with hair dye. For no treatment, the paper was towel dried and then dried directly with a dryer.

Measurement (Spectrophotometer SE-7700, Nippon Denshoku industries Co., Ltd.)

The color of 6 sites (root, middle, tip) was measured for one hair strand, and the average value was used.

After dyeing, measurements were taken after 1 st, 5 th and 10 th destruction. The extent of color change was observed by measuring Δ E based on the Lab value immediately after dyeing and the Lab value after destruction.

The results are shown in table 6 and fig. 1.

TABLE 6

The larger the value, the more the color change, and it is found that the formulation 1 of example 1 prevents the color fading of hair compared to the hair strand not coated with the formulation 1. In particular, the discoloration-inhibiting effect after the 10 th destruction treatment was more remarkable than that of preparation 2 in which no fullerene was disposed and removed.

Example 52

It is known that when hair is damaged by oxidation, the S-S bond of cystine is oxidized to produce cysteine. Therefore, the amount of cysteine in the hair generated by ultraviolet rays was determined for the cosmetic composition of example 1. Human black hair (japanese beauty co., ltd. ((r.) ビューラックス)) was cleaned with a 1% sodium lauryl sulfate aqueous solution, washed with water, and dried naturally. Then, the resulting solution was cut into about 5cm, fixed on a holding member, and the infrared absorption spectrum was measured to calculate the absorption wavelength of the cysteine residue (1040 cm) ^-1) Relative to amide absorption (1634 cm)^-1) The ratio of absorption wavelengths of (1) (Affinity-1, DuraSamplIR II, Shimadzu corporation). Subsequently, the coating liquid was completely dried with a drier after applying water or the aqueous solution of example 1 diluted to 5%. Irradiating hair with ultraviolet rays (about 300J/cm) under UVB lamp²70 hours). Subsequently, the sample was cleaned, dried, and the infrared absorption spectrum was measured again. It was previously confirmed that the coating of the formulation of example 1 had no effect on the spectrum under these conditions.

As a result, as shown in fig. 2, it was confirmed that in the case of the water-only treatment, the absorption of S ═ O indicating cysteine increased after the ultraviolet irradiation, whereas the amount of cysteine was not changed in the hair treated with the aqueous solution (5%) of example 1. From the results, it is understood that the preparation of example 1 can effectively suppress oxidative damage of the hair by ultraviolet rays.

Claims (5)

1. A cosmetic composition characterized by containing, as essential components,

the cosmetic composition contains the following components (A) to (E) and has a bicontinuous structure:

(A) an oil agent containing an ester oil in which 0.001 to 0.3 wt% of fullerene is dissolved: 1 to 20 wt%;

(B) one or more selected from polyglycerin fatty acid ester and polyoxyethylene glycerin fatty acid ester: 15-45 wt%;

(C) Glycerol, or glycerol with 1, 3-butanediol: 10 to 35 wt%;

(D) oil agent in which fullerene is not dissolved: 5 to 30 wt%; and

(E) water: 10 to 40 wt%.

2. The cosmetic composition according to claim 1, wherein,

the cosmetic composition is uniformly colored in the hue of each pigment in both cases of adding a liquid in which a water-soluble pigment is dissolved in water and of adding a liquid in which an oil-soluble pigment is dissolved in oil.

3. The cosmetic composition according to claim 1 or 2, wherein,

the ester oil in the component (A) is one or two or more selected from lactone derivatives represented by the following general formula (1),

chemical formula 1

In the formula (1), n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms.

4. A cosmetic material is provided, wherein,

the composition for cosmetic materials according to claim 1 or 2 dispersed in an aqueous medium.

5. A hair cosmetic composition, wherein,

the composition for cosmetic materials according to claim 1 or 2 dispersed in an aqueous medium.

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