JP7309428B2 - Phosphatidylinositol-containing cosmetics or skin preparations for external use - Google Patents

Description

TECHNICAL FIELD The present invention relates to a cosmetic or topical skin preparation containing a phospholipid composition comprising phosphatidylinositol and lecithin, a polyhydric alcohol, a nonionic surfactant, and water.

Lecithin is a general term for glycerophospholipids obtained from animals or plants, and is widely used as a natural emulsifier in foods, cosmetics, pharmaceuticals, and the like. The constituents of lecithin are classified according to the structure of the polar group attached to the phosphate group, such as phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), phosphatidylinositol (PI), and phosphatidic acid (PA). is known to be the major component. In recent years, research has focused on the functions and efficacy of each of these, among which it is known that PIs are deeply involved in intracellular and extracellular signaling functions. Physiological effects such as reduction and increase in HDL cholesterol have been reported. As for cosmetic applications, physiological actions such as increasing the amount of hyaluronic acid in the skin (Patent Document 1) and enhancing Nrf2 activity (Patent Document 2) have been reported. When using PI as an active ingredient in various applications, it is important to obtain a composition containing PI at a high concentration. However, there are problems in terms of manufacturing complexity and cost. On the other hand, recently, a method for efficiently producing PI using phospholipase B that specifically acts on phospholipids other than PI has been developed (Patent Documents 4 and 5), and a composition containing a high concentration of PI is industrially produced. It has become possible to obtain it widely and inexpensively, and further applications of PI are expected. However, PI is inferior to other phospholipids in emulsifying power, and it is very difficult to uniformly disperse PI alone in water.

Techniques for dispersing phospholipids in water using polyhydric alcohols are already known (for example, Patent Documents 6 and 7), but techniques for dispersing phosphatidylinositol using polyhydric alcohols were not known. .

WO2009/110205 JP 2011-168541 A JP-A-60-246305 WO2007/010892 JP 2015-27260 JP-A-60-153938 JP H11-130651

The inventors of the present invention conducted various studies on phosphatidylinositol, which had not been widely used for cosmetics, and found that it has various physiological activities, including hitherto unknown effects, and that it can be used as an active ingredient in cosmetics. found to be very useful. On the other hand, they have found that it is very difficult to incorporate them into cosmetics due to their low dispersibility in water. Accordingly, an object of the present invention is to provide a cosmetic or external preparation for skin in which phosphatidylinositol is simply and stably dispersed in water.

The inventors of the present invention conducted intensive studies to solve the above problems, and as a result, found that a cosmetic or external preparation for skin containing the following components (A) to (D) can solve the above problems. completed.
(A) A phospholipid composition comprising the following components (A1) and (A2): (A1) phosphatidylinositol (A2) lecithin (B) polyhydric alcohol (C) nonionic surfactant (D) water

By using the present invention, phosphatidylinositol can be easily dispersed in water, and it is possible to easily obtain a cosmetic or external preparation for skin with excellent dispersion stability and transparency. In addition, the cosmetic or external preparation for skin of the present invention exhibits excellent bioactive effects such as hyaluronic acid production promoting action, intracellular active oxygen scavenging action, whitening action, and collagen production promoting action.

The present invention is a cosmetic or external skin preparation containing the following components (A) to (D) as essential components.
(A) Phospholipid composition comprising the following components (A1) and (A2): (A1) phosphatidylinositol (A2) lecithin (B) polyhydric alcohol (C) nonionic surfactant (D) water

Phosphatidylinositol (hereinafter also referred to as PI) of the component (A1) used in the present invention is a type of phospholipid present in plants such as soybean, rapeseed, sunflower, corn, and palm in the natural world. contained in lecithin extracted from By fractionating such lecithin by solvent fractionation, column purification, or a method using an enzyme, which will be described later, it is possible to obtain a composition containing PI at a high concentration. A PI-containing composition can be used as component (A1). As the high-concentration PI-containing composition, one having a PI content of 40% by weight or more, preferably 50% by weight or more, is preferably used. As a method for producing a high-concentration PI-containing composition, in addition to the long-known solvent fractionation and column purification, phospholipase B that specifically acts on phospholipids other than PI is used, and PIs such as PC, PE, and PA are used. A method of selectively hydrolyzing phospholipids other than phospholipids and then extracting the remaining PI with a solvent has been developed (Patent Documents 4 and 5). For this reason, it is possible to industrially obtain a composition containing a high concentration of PI at a low cost, and Soybrain PI50 (manufactured by Unitech Foods) is sold as a commercial product. Such commercial products can be preferably used in the present invention.

The component (A2) lecithin used in the present invention includes natural lecithin obtained from plants such as soybean, rapeseed, sunflower, safflower, peanut, cottonseed, corn, rice, and barley, and egg yolk, and hydrogenated products thereof. can be exemplified. Furthermore, these may be derivatives modified with a polyoxyalkylene group such as polyethylene glycol. These may be used alone or in combination of two or more. In general, natural plant-derived lecithins contain about 30% by weight of phosphatidylcholine (hereinafter also referred to as PC), and lecithins with a higher PC content by solvent fractionation are commercially available. In the present invention, it is preferable to use one with a higher PC content from the viewpoint of improving dispersibility. Good to have. As described above, plant-derived lecithin contains about 10 to 20% of PI, but lecithin whose PC content is increased by solvent fractionation contains almost no PI because it is removed during the fractionation process. Therefore, in order to obtain a PI-containing phospholipid composition with a high PC content, it is necessary to mix a high-concentration PI-containing composition with a PC-enriched lecithin. Lecithin obtained from egg yolk naturally contains about 70% by weight of PC (PI is not included), so it can be preferably used as the component (A2). preferable. From the viewpoint of improving the feeling of use of the cosmetic composition or external preparation for skin of the present invention, it is preferable to use a mixture of hydrogenated lecithin and non-hydrogenated lecithin as the component (A2). The mixing ratio of hydrogenated lecithin and non-hydrogenated lecithin is preferably 99:1 to 70:30, more preferably 97:3 to 80:20 by weight.

In the present invention, component (A2) is used for the purpose of assisting dispersion of component (A1). The mixing ratio of components (A1) and (A2) in the present invention is not particularly limited, but it is preferable to mix them in a weight ratio of 5:95 to 50:50, preferably 10:90 to 40:60.

The amount of component (A) used in the present invention is not particularly limited, but is preferably 0.001 to 5% by weight from the viewpoint of the dispersion stability and transparency of the obtained cosmetic or topical skin preparation. is 0.005 to 2% by weight, most preferably 0.01 to 1% by weight.

The polyhydric alcohol of component (B) used in the present invention is used for the purpose of easily and stably dispersing component (A) in water. Specific examples of component (B) include ethylene glycol, propylene glycol, 1,3-propanediol, 1,2-butylene glycol, 1,3-butylene glycol, 2,3-butylene glycol, 2-methyl-1, 3-propanediol, 3-methyl-1,3-butanediol (isopentyldiol), tetramethylene glycol, hexylene glycol, caprylyl glycol, 1,2-pentanediol (pentylene glycol), 1,2-hexane Dihydric alcohols such as diols, 1,2-heptanediol, 1,2-octanediol and 1,2-decanediol; Trihydric alcohols such as glycerin, trimethylolpropane and 1,2,6-hexanetriol sugar alcohols such as sorbitol, xylitol, erythritol, maltitol, mannitol, and pentaerythritol; glyceryl ethers such as ethylglycerin, butylglycerin, hexylglycerin, and ethylhexylglycerin; diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene glycol, dipropylene Examples include polyhydric alcohol polymers such as glycol, tripropylene glycol, polypropylene glycol, diglycerin, triglycerin, tetraglycerin, and polyglycerin. These may be used alone or in combination of two or more. Among these, glycerin, propylene glycol, 1,3-propanediol, 1,2-butylene glycol, 1,3-butylene glycol, hexylene glycol, 1, and 2-pentanediol and 1,2-hexanediol are preferred.

In the cosmetic or external preparation for skin of the present invention, the term “transparent in appearance” means that when a sample is placed in a glass bottle with a diameter of 3.5 cm and observed from the side, the background of the liquid can be seen through. To tell. When measuring turbidity with a spectrophotometer, a sample is placed in a cell with a thickness of 1 cm, and the transmittance is 55% or more when measured at a wavelength of 600 nm.

The blending ratio of the components (A) and (B) used in the present invention is 1:5 to 1:200 by weight from the viewpoint of obtaining a cosmetic composition or topical skin preparation having excellent transparency and dispersion stability. , preferably in a ratio of 1:10 to 1:150.

The component (C) nonionic surfactant used in the present invention is used for the purpose of improving the dispersion stability of the component (A) and the transparency of the resulting dispersion. Specific examples of component (C) include glycerin fatty acid esters, polyglycerin fatty acid esters, sucrose fatty acid esters, mannosylerythritol lipids, polyoxyethylene glycerin fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene fatty acid esters, polyoxy ethylene alkyl ether and the like. These may be used alone or in combination of two or more. Among these, glycerin fatty acid esters, polyglycerin fatty acid esters, sucrose fatty acid esters, mannosylerythritol lipids, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene alkyl ethers are preferred.

Specific examples of glycerin fatty acid esters include monoesters of fatty acids having 8 to 22 carbon atoms and glycerin. Preferred among these are glyceryl caprylate, glyceryl caprate, glyceryl laurate, glyceryl myristate, glyceryl palmitate, glyceryl stearate, glyceryl oleate, glyceryl isostearate, glyceryl behenate, and glyceryl caprylate. , glyceryl caprate and glyceryl laurate are most preferred.

Specific examples of polyglycerol fatty acid esters include monoesters, diesters, triesters, tetraesters, etc. of fatty acids having 8 to 22 carbon atoms and polyglycerol having a degree of polymerization of 2 to 20, more preferably 6 to 12. mentioned. Preferred among these are polyglyceryl caprylate, polyglyceryl caprate, polyglyceryl laurate, polyglyceryl myristate, polyglyceryl palmitate, polyglyceryl stearate, polyglyceryl oleate, polyglyceryl isostearate, polyglyceryl behenate, polyglyceryl dicaprylate, and polyglyceryl dicaprate. , Polyglyceryl Dilaurate, Polyglyceryl Dimyristate, Polyglyceryl Dipalmitate, Polyglyceryl Distearate, Polyglyceryl Dioleate, Polyglyceryl Diisostearate, Polyglyceryl Dibehenate, Polyglyceryl Tricaprylate, Polyglyceryl Tricaprate, Polyglyceryl Trilaurate, Polyglyceryl Trimyristate, Tripalmitin Polyglyceryl acid, polyglyceryl tristearate, polyglyceryl trioleate, polyglyceryl triisostearate, polyglyceryl tribehenate, polyglyceryl caprylate, polyglyceryl caprate, polyglyceryl laurate, polyglyceryl dicaprylate, polyglyceryl dicaprate, polyglyceryl dilaurate. Most preferred.

Specific examples of sucrose fatty acid esters include monoesters, diesters, triesters and tetraesters of fatty acids having 8 to 22 carbon atoms and sucrose. Among these, sucrose laurate, sucrose myristate, sucrose palmitate, sucrose stearate, sucrose oleate, sucrose behenate, sucrose erucate, sucrose dilaurate, sucrose dimyristate, sucrose dipalmitate, distearin sucrose acid, sucrose dioleate, sucrose dibehenate, sucrose dierucate, sucrose trilaurate, sucrose trimyristate, sucrose tripalmitate, sucrose tristearate, sucrose trioleate, sucrose tribehenate, sucrose trierucate and the like. , sucrose laurate, sucrose myristate, sucrose palmitate, sucrose dilaurate, sucrose dimyristate, sucrose dipalmitate.

（式中、Ｒ１、Ｒ２は水素又は炭素数２～２４の脂肪族アシル基を表す（ただし同時に水素はとらない）。また、Ｒ３、Ｒ４は水素又はアセチル基を表し、Ｒ５は水素又は炭素数２～２４の脂肪族アシル基を表す。） Mannosylerythritol lipid is a general term for compounds represented by the following general formula (1). Specific examples thereof include: R1 and R2 in general formula (1) are acyl groups, R3 and R4 are acetyl groups, and R5 is hydrogen. MEL-A which is a compound of the general formula (1), R1 and R2 of the general formula (1) are acyl groups, R3 is hydrogen, R4 is an acetyl group, and R5 is a hydrogen compound MEL-B, R1 and R2 of the general formula (1) is an acyl group, R3 is an acetyl group, R4 is hydrogen, and R5 is hydrogen. and MEL-D. Of these, MEL-B or MEL-C is preferred, and MEL-B is most preferred.

(Wherein, R1 and R2 represent hydrogen or an aliphatic acyl group having 2 to 24 carbon atoms (but do not take hydrogen at the same time).In addition, R3 and R4 represent hydrogen or an acetyl group, and R5 represents hydrogen or a Represents 2 to 24 aliphatic acyl groups.)

Specific examples of polyoxyethylene glycerin fatty acid esters include glycerin polyoxyethylene adducts having a polyoxyethylene (E.O) addition mole number of 4 to 200, more preferably 8 to 100, and fatty acids having 8 to 22 carbon atoms. and monoesters, diesters, triesters, and the like. Preferred among these are polyoxyethylene glycerin caprylate, polyoxyethylene glycerin caprate, polyoxyethylene glycerin laurate, polyoxyethylene glycerin myristate, polyoxyethylene glycerin palmitate, polyoxyethylene glycerin stearate, and olein. polyoxyethylene glycerin acid, polyoxyethylene glycerin isostearate, polyoxyethylene glycerin dicaprylate, polyoxyethylene glycerin dicaprate, polyoxyethylene glycerin dilaurate, polyoxyethylene glycerin dimyristate, polyoxyethylene glycerin dipalmitate, Polyoxyethylene glyceryl distearate, polyoxyethylene glyceryl dioleate, polyoxyethylene glyceryl diisostearate, polyoxyethylene glyceryl tricaprylate, polyoxyethylene glyceryl tricaprate, polyoxyethylene glyceryl trilaurate, polyoxyethylene glyceryl trimyristate, Polyoxyethylene glyceryl tripalmitate, polyoxyethylene glyceryl tristearate, polyoxyethylene glyceryl trioleate, polyoxyethylene glyceryl triisostearate, polyoxyethylene glyceryl caprylate, polyoxyethylene glyceryl caprate, Most preferred is polyoxyethylene glycerol laurate.

Specific examples of polyoxyethylene sorbitan fatty acid esters include sorbitan-polyoxyethylene adducts having a polyoxyethylene (EO) addition mole number of 4 to 200, more preferably 8 to 100, and fatty acids having 8 to 22 carbon atoms. and monoesters, diesters, triesters, tetraesters, and the like. Preferred among these are polyoxyethylene sorbitan caprylate, polyoxyethylene sorbitan caprate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan myristate, polyoxyethylene sorbitan palmitate, polyoxyethylene sorbitan stearate, and olein. polyoxyethylene sorbitan acid, polyoxyethylene sorbitan isostearate, polyoxyethylene sorbitan dicaprylate, polyoxyethylene sorbitan dicaprate, polyoxyethylene sorbitan dilaurate, polyoxyethylene sorbitan dimyristate, polyoxyethylene sorbitan dipalmitate, Polyoxyethylene sorbitan distearate, polyoxyethylene sorbitan dioleate, polyoxyethylene sorbitan diisostearate, polyoxyethylene sorbitan tricaprylate, polyoxyethylene sorbitan tricaprate, polyoxyethylene sorbitan trilaurate, polyoxyethylene sorbitan trimyristate, polyoxyethylene sorbitan tripalmitate, polyoxyethylene sorbitan tristearate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan triisostearate, polyoxyethylene sorbitan caprylate, polyoxyethylene sorbitan caprate, Most preferred are polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan oleate, and polyoxyethylene sorbitan isostearate.

Specific examples of polyoxyethylene fatty acid esters include monoesters of polyoxyethylene (E.O) having an added mole number of 4 to 200, more preferably 8 to 100, and a fatty acid having 8 to 22 carbon atoms. , diesters, and the like. Preferred among these are polyoxyethylene caprylate, polyoxyethylene caprate, polyoxyethylene laurate, polyoxyethylene myristate, polyoxyethylene palmitate, polyoxyethylene stearate, polyoxyethylene oleate, and isostearin. polyoxyethylene acid, polyoxyethylene behenate, polyoxyethylene dicaprylate, polyoxyethylene dicaprate, polyoxyethylene dilaurate, polyoxyethylene dimyristate, polyoxyethylene dipalmitate, polyoxyethylene distearate, diolein acid polyoxyethylene, polyoxyethylene diisostearate, polyoxyethylene dibehenate, etc., and polyoxyethylene caprylate, polyoxyethylene caprate, and polyoxyethylene laurate are most preferred.

Specific examples of polyoxyethylene alkyl ethers include polyoxyethylene (E.O) of 4 to 200 moles, more preferably 8 to 4 to 200 moles, more preferably 8 to 200 moles of polyoxyethylene (E.O) in a lipophilic compound having a hydroxyl group such as an alcohol having 8 to 32 carbon atoms or castor oil. Compounds with 100 mol additions can be mentioned. Among these, preferred are polyoxyethylene capryl ether, polyoxyethylene caprylyl ether, polyoxyethylene lauryl ether, polyoxyethylene myristyl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene oleyl ether, Polyoxyethylene isostearyl ether, polyoxyethylene behenyl ether, polyoxyethylene cholesterol ether, polyoxyethylene phytosterol ether, polyoxyethylene hydrogenated castor oil, etc., polyoxyethylene capryl ether, polyoxyethylene caprylyl ether, Most preferred are polyoxyethylene lauryl ether, polyoxyethylene cholesterol ether, polyoxyethylene phytosterol ether, and polyoxyethylene hydrogenated castor oil.

The blending ratio of the components (A) and (C) used in the present invention is 1:0.1 to 1:0.1 by weight from the viewpoint of obtaining a cosmetic or topical skin preparation having excellent transparency and dispersion stability. :10, preferably 1:0.2 to 1:5.

The component (D) water used in the present invention is not particularly limited as long as it can be used in general cosmetics, such as purified water, ion-exchanged water, distilled water, natural water, deep sea water, and hydrogen water. can be used. Moreover, the pH may be adjusted with an acid, an alkali, a buffer, a chelating agent, or the like, or a preservative may be added.

For the purpose of improving the dispersion stability, the cosmetic composition or external preparation for skin of the present invention may further contain sterols or triterpenes as component (E). Specific examples of component (E) include animal-derived sterols such as cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, desmosterol; stigmasterol, sitosterol, campesterol, brassicasterol, and mixtures thereof such as phytosterol. Plant-derived sterols; microorganism-derived sterols such as ergosterol; γ-oryzanol; ursolic acid; glycyrrhetinic acid; These may be used alone or in combination of two or more. Among these, cholesterol, phytosterol, and γ-oryzanol are preferred. The amount of component (E) is not particularly limited, but the weight ratio of components (A) and (E) is 200:1 to 1:1, preferably 100:1 to 2:1. They should be blended in proportions.

As a method for producing the cosmetic composition or external preparation for skin of the present invention, first, components (A), (B) and (C) or components (A), (B), (C) and (E) are heated and stirred. It can be prepared by mixing to prepare a polyhydric alcohol dispersion, and adding water to the obtained polyhydric alcohol dispersion while stirring, or adding the polyhydric alcohol dispersion to water while stirring. By such a method, phosphatidylinositol, which is difficult to disperse in water by itself, can be easily and stably dispersed in water, and an aqueous dispersion having excellent transparency and dispersion stability can be obtained. .

Phosphatidylinositol, which is the component (A1) of the present invention, is excellent in hyaluronic acid production promoting action, intracellular active oxygen scavenging action, whitening action, collagen production promoting action, etc. as described in Japanese Patent Application No. 2018-083875. The PI-containing cosmetic or topical preparation for skin of the present invention also has an excellent physiological activity.

The cosmetic composition or external preparation for skin of the present invention may optionally contain water and additive components usually blended in cosmetics, such as oily bases, surfactants, alcohols, moisturizers, polymers, thickeners, and gels. agent, antioxidant, antiseptic, bactericide, chelating agent, pH adjuster/acid/alkali, UV absorber, whitening agent, solvent, exfoliating/dissolving agent, antipruritic, anti-inflammatory agent, antiperspirant, cooling agent agents, antihistamines, astringents, stimulants, hair growth agents/blood circulation promoters, reducing agents/oxidizing agents, polymer powders, hydroxy acids, vitamins and their derivatives, sugars and their derivatives, organic acids, enzymes , nucleic acids, hormones, inorganic powders, fragrances, pigments, etc. may be contained to such an extent that the effects of the present invention are not impaired.

Oily bases include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, arachyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, cerachyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, Higher alcohols such as 2-octyldodecanol and dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, Palmitoleic acid, oleic acid, linoleic acid, linoleic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acids, dimer acid, hydrogenated dimer acid, etc. Fatty acids and metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium salts, sodium salts thereof, nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin , α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, petrolatum, solid paraffin and other hydrocarbons; candelilla wax, carnauba wax, rice wax, Japan wax, beeswax, montan wax , ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, Fischer-Tropsch wax, polyethylene wax, ethylene-propylene copolymer; coconut oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado Oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, meadowfoam oil, persic oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower oil, wheat. Vegetable oils such as germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil; Animal fats and oils such as horse fat, egg yolk oil, mink oil, turtle oil; Animal waxes such as spermaceti, lanolin, and orange roughy oil; Liquid lanolin, reduced lanolin, adsorbed refined lanolin, acetic acid lanolin, acetic acid liquid lanolin , hydroxylanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin acetate alcohol, lanolins such as acetic acid (cetyl/lanolyl) ester; lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidyl Sphingophospholipids such as inositol and sphingomyelin, phosphatidic acid, cyclic lysophosphatidic acid or its salts, phospholipids such as lysolecithin; hydrogenated soybean phospholipids, partially hydrogenated soybean phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated Phospholipid derivatives such as egg yolk phospholipids; sapogenins; saponins; ), di(cholesteryl/octyldodecyl) N-lauroyl-L-glutamate, di(phytosteryl/behenyl/octyldodecyl) N-lauroyl-L-glutamate, di(phytosteryl/octyldodecyl) N-lauroyl-L-glutamate, N - acyl sarcosine alkyl esters such as isopropyl lauroyl sarcosine, cholesteryl 12-hydroxystearate, cholesteryl macadamia nut oil, phytosteryl macadamia nut oil, phytosteryl sunflower seed oil, phytosteryl isostearate, cholesteryl soft lanolin, hard cholesteryl lanolin, long chain sterol esters such as branched fatty acid cholesteryl and long-chain α-hydroxy fatty acid cholesteryl; lipid complexes such as phospholipid/cholesterol complex and phospholipid/phytosterol complex; , cetyl palmitate, octyldodecyl palmitate, cetyl octanoate, hexyldecyl octanoate, isotridecyl isononanoate, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, neodecanoic acid Octyldodecyl, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, octyldodecyl lanolin fatty acid, dicaprylyl carbonate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, hydrogenated castor oil isostearate, ethyl oleate, ethyl avocado oil , isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, isopropyl lanolin fatty acid, methylheptyl laurate, methylheptyl myristate, methylheptyl palmitate, methylheptyl isostearate, diethyl sebacate, diisopropyl sebacate, sebacin Monoalcohol carboxylic acid esters such as dioctyl acid, diisopropyl adipate, dibutyloctyl sebacate, diisobutyl adipate, dioctyl adipate, dioctyl succinate, triethyl citrate; cetyl lactate, diisostearyl malate, hydrogenated monoisostearate Oxyesters such as castor oil and γ-erucalactone; Glyceryl myristate/stearate, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), eicosane diacid glyceryl behenate, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, neopentyl dioctanoate Glycol, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol dioctoate, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenated rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate , (isostearic acid/sebacic acid) ditrimethylolpropane, pentaerythrityl triethylhexanoate, (hydroxystearic acid/stearate/rosin acid) dipentaerythrityl, diglyceryl diisostearate, polyglyceryl tetraisostearate, polyglyceryl-10 nonisostearate, deca (Erucic Acid/Isostearic Acid/Ricinoleic Acid) Polyglyceryl-8, (Hexyldecanoic Acid/Sebacic Acid) Diglyceryl Oligoester, Glycol Distearate (Ethylene Glycol Distearate), 3-Methyl-1,5-Pentanediol Dineopentanoate, Dineopentane polyhydric alcohol fatty acid esters such as acid 2,4-diethyl-1,5-pentanediol; alkyl ethers such as dicaprylyl ether; diisopropyl dimer dilinoleate, diisostearyl dimer dilinoleate, didimer dilinoleate (isostearyl/phytosteryl), dimer dilinoleic acid (phytosteryl/behenyl), dimer dilinoleic acid (phytosteryl/isostearyl/cetyl/stearyl/behenyl), dimer dilinoleyl dimer dilinoleate, dimer dilinoleyl diisostearate, Dimer acid or dimer diol derivatives such as dimer dilinoleyl hydrogenated rosin condensate, dimer dilinoleic acid hydrogenated castor oil, hydroxyalkyl dimer dilinoleyl ether; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide de (cocamide DEA), lauric acid monoethanolamide (Lauramide MEA), lauric acid diethanolamide (Lauramide DEA), lauric acid monoisopropanolamide (Lauramide MIPA), palmitic acid monoethanolamide (Partamide MEA), palmitic acid diethanolamide ( Partamide DEA), fatty acid alkanolamides such as coconut oil fatty acid methylethanolamide (cocamide methyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopenta siloxane), phenyltrimethicone, diphenyldimethicone, phenyldimethicone, (aminoethylaminopropylmethicone/dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified silicones such as aminopropyl dimethicone and amodimethicone, cation-modified Silicone, polyether-modified silicone such as dimethicone copolyol, polyglycerin-modified silicone, sugar-modified silicone, carboxylic acid-modified silicone, phosphoric acid-modified silicone, sulfuric acid-modified silicone, alkyl-modified silicone, fatty acid-modified silicone, alkyl ether-modified silicone, amino acid-modified silicone, peptide-modified silicone, fluorine-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone, alkyl-modified and polyether-modified silicone, amidoalkyl-modified silicone, aminoglycol-modified silicone, aminophenyl-modified silicone, poly Silicones such as siloxane/oxyalkylene copolymers; fluorine-based oils such as perfluorodecane, perfluorooctane, and perfluoropolyether are preferred.

Moisturizers and texture improvers include glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Polyols such as trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol/propylene glycol copolymer, and polymers thereof; diethylene glycol monoethyl ether Glycol alkyl ethers such as (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol dibutyl ether; (eicosanedioic acid/tetradecanedioic acid) polyglyceryl-10, tetradecanedioic acid polyglyceryl-10, cyclohexanedicarboxylic acid water-soluble esters such as bisethoxydiglycol; sugar alcohols such as sorbitol, xylitol, erythritol, mannitol and maltitol; glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, Trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ-cyclodextrins and modified cyclodextrins such as maltosylation and hydroxyalkylation), β-glucan, chitin, chitosan, Sugars and derivatives thereof such as heparin and derivatives, pectin, arabinogalactan, dextrin, dextran, glycogen, ethyl glucoside, glucosylethyl methacrylate polymer or copolymer; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate; mucoitin sulfate , caronin sulfate, keratosulfate, dermatan sulfate; white fungus extract, white fungus polysaccharide; fructans such as inulin and levan; fucoidan; urea; 2-pyrrolidone-5-carboxylic acid and salts thereof such as sodium; betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid , glutamine, asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine and other amino acids and their salts; Degraded Collagen, Hydroxypropylammonium Chloride Hydrolyzed Collagen, Elastin Degraded Peptide, Keratin Degraded Peptide, Hydrolyzed Keratin, Conchiolin Degraded Peptide, Hydrolyzed Conchiolin, Silk Proteolytic Peptide, Hydrolyzed Silk, Sodium Lauroyl Hydrolyzed Silk, Soybean Proteolytic Peptide , wheat proteolytic peptides, hydrolyzed wheat proteins, casein-degrading peptides, protein peptides such as acylated peptides and derivatives thereof; palmitoyl oligopeptides, palmitoyl pentapeptides, palmitoyl tetrapeptides and other acylated peptides; silylated peptides; Lactic acid bacteria culture solution, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesame lignan glycoside, glutathione, albumin, whey; choline chloride, phosphorylcholine; placenta extract, aerastin, collagen, aloe extract, hamamelis Water, loofah water, chamomilla extract, licorice extract, comfrey extract, silk extract, rose rose extract, yarrow extract, eucalyptus extract, melilot extract and other animal and plant extracts, natural ceramides (types 1, 2, 3, 4) , 5, 6), ceramides such as hydroxyceramides, pseudoceramides, glycosphingolipids, ceramides, and sugar-ceramide-containing extracts are preferred.

Preferred surfactants include anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, polymeric surfactants, and the like. There is no particular limitation on the HLB of the surfactant, and a surfactant with a low HLB of about 1 to a surfactant with a high HLB of about 20 can be used, and a combination of a low HLB and a high HLB is also preferred. Examples of preferred surfactants include anionic surfactants such as fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate salts such as sodium lauryl sulfate, triethanolamine lauryl sulfate and ammonium lauryl sulfate; Polyoxyethylene alkyl sulfates such as sodium sulfate, triethanolamine laureth sulfate; sodium cocoyl methyl taurate, potassium cocoyl methyl taurate, sodium lauroyl methyl taurate, sodium myristoyl methyl taurate, sodium lauroyl methyl alanine, sodium lauroyl sarcosine, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amines, sodium methylalanine lauroyl glutamate; sodium cocoyl glutamate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditriethanolamine palmitoyl aspartate, cocoyl alanine triethanolamine , acyl amino acid salts such as dilauroyl glutamic acid lysine Na; polyoxyethylene alkyl ether acetate salts such as sodium laureth acetate; succinate ester salts such as lauroyl monoethanolamide sodium succinate; fatty acid alkanolamide ether carboxylate; fatty acid alkanolamide sulfates; fatty acid glyceride sulfates such as hydrogenated coconut oil fatty acid sodium glycerol sulfate; alkylbenzene polyoxyethylene sulfates; olefin sulfonates such as sodium α-olefin sulfonate; Alkyl sulfosuccinates such as disodium lauryl acid and dioctyl sodium sulfosuccinate; disodium laureth sulfosuccinate, monolauroyl monoethanolamide sodium polyoxyethylene sulfosuccinate, and alkyl ether sulfosuccinates such as sodium lauryl polypropylene glycol sulfosuccinate; tetradecyl Alkylbenzenesulfonates such as sodium benzenesulfonate and triethanolamine tetradecylbenzenesulfonate; alkylnaphthalenesulfonates; alkanesulfonates; α-sulfo fatty acid methyl ester salts; acyl isethionates; Alkyl sulfoacetates; alkyl ether phosphates such as sodium laureth phosphate, sodium dilaureth phosphate, sodium trilaureth phosphate, sodium monooleth phosphate; alkyl phosphates such as potassium lauryl phosphate; sodium caseinate; acid; fatty acid amide ether phosphate; phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof; Ionic surfactants, etc.; nonionic surfactants include laureth (polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), beheneth (polyoxyethylene behenyl ether), isosteareth (polyoxyethylene isostearyl ether), octyldodeceth (polyoxyethylene octyldodecyl ether), and other polyoxyethylene alkyl ethers with various polyoxyethylene addition numbers; polyoxyethylene alkylphenyl ether; Oxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, polyoxy castor oil and hydrogenated castor oil derivatives such as ethylene hydrogenated castor oil maleic acid; polyoxyethylene phytosterol; polyoxyethylene cholesterol; polyoxyethylene cholestanol; Polyethylene such as cetyl ether, polyoxyethylene/polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene/polyoxypropylene monobutyl ether, polyoxyethylene/polyoxypropylene hydrogenated lanolin, polyoxyethylene/polyoxypropylene glycerin ether, etc. Oxyethylene/polyoxypropylene alkyl ether; Polyoxyethylene/polyoxypropylene glycol; PPG-9 diglyceryl (poly)glycerin Polyoxypropylene glycol; Glycerin fatty acid partial esters such as glyceryl oleate, glyceryl cocoate, monocottonseed glycerin, glyceryl monoerucate, glyceryl sesquioleate, α,α'-pyroglutamate glyceryl oleate, glyceryl monostearate malic acid; stearic acid Polyglyceryl-2, 3, 4, 5, 6, 8, 10, polyglyceryl-6, 10, polyglyceryl-2 tristearate, polyglyceryl-10 destearate, polyglyceryl-2 isostearate , 3, 4, 5, 6, 8, 10, polyglyceryl-2 diisostearate (diglyceryl diisostearate), 3, 10, polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate , polyglyceryl-10 decaisostearate, polyglyceryl-2, 3, 4, 5, 6, 8, 10, polyglyceryl-6 dioleate, polyglyceryl-2 trioleate, polyglyceryl-10 decooleate polyglycerol fatty acid esters such as; ethylene glycol mono fatty acid esters such as ethylene glycol monostearate; propylene glycol mono fatty acid esters such as propylene glycol monostearate; pentaerythritol partial fatty acid esters; Maltitol ether; sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol penta-2-ethylhexyl sorbitan, tetra -Sorbitan fatty acid esters such as diglycerol sorbitan 2-ethylhexylate; sugar derivative partial esters such as sucrose fatty acid esters, methylglucoside fatty acid esters and trehalose undecylenate; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; lanolin alcohol; reduced lanolin; polyoxyethylene fatty acid mono- and diesters such as polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene dioleate; Ethylene/propylene glycol fatty acid ester; polyoxyethylene glycerin fatty acid ester such as polyoxyethylene monooleate such as polyoxyethylene glycerin monostearate, polyoxyethylene glycerin monoisostearate, polyoxyethylene glycerin triisostearate; Polyoxyethylene sorbitan fatty acid esters such as oxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol Polyoxyethylene sorbitol fatty acid esters such as monooleate, polyoxyethylene sorbitol pentaoleate, polyoxyethylene sorbitol monostearate; polyoxyethylene methyl glucoside fatty acid esters; polyoxyethylene alkyl ether fatty acid esters; polyoxyethylene sorbitol beeswax, etc. Polyoxyethylene animal and vegetable oils and fats; isostearyl glyceryl ether, chimyl alcohol, selachyl alcohol, bacyl alcohol and other alkyl glyceryl ethers; polyhydric alcohol alkyl ether; polyoxyethylene alkylamine; tetrapolyoxyethylene/tetrapolyoxy Propylene-ethylenediamine condensates; natural surfactants such as saponin and sophorolipid; polyoxyethylene fatty acid amides; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (Lauramide MEA), Lauric Acid Diethanolamide (Lauramide DEA), Lauric Acid Monoisopropanolamide (Lauramide MIPA), Palmitic Acid Monoethanolamide (Partamide MEA), Palmitic Acid Diethanolamide (Partamide DEA), Coconut Fatty Acid Methylethanolamide ( fatty acid alkanolamides such as cocamide methyl MEA); alkyldimethylamine oxides such as lauramine oxide, cocamine oxide, stearamine oxide and behenamine oxide; alkylethoxydimethylamine oxides; polyoxyethylene alkylmercaptan; Silicone-based nonionic surfactants such as polyether-modified silicones, polysiloxane/oxyalkylene copolymers, polyglycerin-modified silicones, and sugar-modified silicones; cationic surfactants such as behentrimonium chloride and steartrimonium Alkyltrimethylammonium chloride such as chloride, cetrimonium chloride and lauryltrimonium chloride; Alkyltrimethylammonium bromide such as stearyltrimonium bromide; Dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; , stearamidoethyldiethylamine and other fatty acid amidoamines and salts thereof; alkyl ether amines such as stearoxypropyldimethylamine and their salts or quaternary salts; ethyl sulfate long-chain branched fatty acids (12-31) aminopropylethyldimethylammonium, ethyl sulfate Fatty acid amide type quaternary ammonium salts such as lanolin fatty acid aminopropylethyldimethylammonium; polyoxyethylene alkylamines and their salts or quaternary salts; alkylamine salts; fatty acid amide guanidinium salts; benzethonium salts; pyridinium salts such as cetylpyridinium chloride; imidazolinium salts; alkylisoquinolinium salts; silicone-based cationic surfactants such as amino-modified silicone, cation-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone; N-alkyl-N,N-dimethylamino acid betaines such as; fatty acid amide alkyl-N,N-dimethylamino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline betaine such as sodium cocoamphoacetate and sodium lauroamphoacetate; Alkylsulfobetaine such as alkyldimethyl taurine; Sulfuric acid betaine such as alkyldimethylaminoethanol sulfate; Phosphate betaine such as alkyldimethylaminoethanol phosphate; Phospholipids such as lipids, lysolecithin, hydrogenated soybean phospholipids, partially hydrogenated soybean phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids, and hydroxylated lecithin; silicone-based amphoteric surfactants; Preferable surfactants include polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum, acrylic acid/methacrylate alkyl copolymers, and various silicone-based surfactants.

Guar gum, locust bean gum, queen's seed, carrageenan, galactan, gum arabic, tara gum, tamarind, furcelleran, karaya gum, tororo mallow, cara gum, tragacanth gum, pectin, pectic acid and sodium are used as polymers, thickeners and gelling agents. Salts such as salts, salts such as alginic acid and sodium salts, mannan; starches such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salts, xanthan gum, pullulan, gellan gum, chitin , chitosan, agar, cassava extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose and salts thereof such as sodium, methylhydroxypropylcellulose, sodium cellulose sulfate, dialkyldimethyl Cellulose and its derivatives such as ammonium sulfate cellulose, crystalline cellulose, and cellulose powder; starch-based polymers such as soluble starch, carboxymethyl starch, methylhydroxypropyl starch, methyl starch, hydroxypropyltrimonium chloride starch, corn starch aluminum octenylsuccinate, etc. starch derivatives; sodium alginate, alginic acid derivatives such as propylene glycol alginate; Polyoxypropylene copolymer; Amphoteric methacrylic acid ester copolymer such as (methacryloyloxyethyl carboxybetaine/alkyl methacrylate) copolymer, (acrylates/stearyl acrylate/ethylamine methacrylate) copolymer; (dimethicone/vinyl dimethicone) cross Polymer, (alkyl acrylate/diacetone acrylamide) copolymer, (alkyl acrylate/diacetone acrylamide) copolymer AMP; partially saponified polyvinyl acetate, maleic acid copolymer; vinylpyrrolidone-dialkylaminoalkyl methacrylate copolymer; Acrylic resin alkanolamine; polyester, water-dispersible polyester; polyacrylamide; polyacrylic acid ester copolymer such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its salt such as sodium salt, acrylic acid and methacrylic acid Ester copolymer; acrylic acid/methacrylate alkyl copolymer; cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride/acrylamide copolymer such as polyquaternium-7, acrylic acid/diallyldimethyl such as polyquaternium-22 ammonium chloride copolymer, acrylic acid/diallyldimethylammonium chloride/acrylamide copolymer such as polyquaternium-39, acrylic acid/cationized methacrylic acid ester copolymer, acrylic acid/cationized methacrylic acid amide copolymer, Acrylic acid/methyl acrylate/methacrylamidopropyltrimethylammonium chloride copolymer such as Polyquaternium-47, chlorinated methacrylic acid choline ester polymer; Saccharide; polyethyleneimine; cationic polymer; polymer of 2-methacryloyloxyethylphosphorylcholine such as polyquaternium-51 and copolymer with butyl methacrylate copolymer; acrylic resin emulsion, polyethyl acrylate emulsion, polyacryl alkyl ester Polymer emulsions such as emulsions, polyvinyl acetate resin emulsions, natural rubber latex, synthetic latex; nitrocellulose; polyurethanes and various copolymers; various silicones; various silicone copolymers such as acrylic-silicone graft copolymers ; Various fluorine-based polymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; Sodium magnesium salt, metal soap, metal dialkyl phosphate, bentonite, hectorite, organically modified clay mineral, sucrose fatty acid ester, and fructo-oligosaccharide fatty acid ester are preferred.

Solvents and propellants include lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol and isobutyl alcohol; glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol and isopentyldiol. Classes: Diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether Glycol ethers such as ethylene glycol monoethyl ether acetate, diethylene glycol monoethyl ether acetate, propylene glycol monoethyl ether acetate and other glycol ether esters; Diethoxyethyl succinate, ethylene glycol disuccinate and other glycol esters; Benzyl Propellants such as alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate, acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbons, next-generation freon; LPG, dimethyl ether, and carbon dioxide are preferred.

Antioxidants include tocopherol (vitamin E), tocopherol derivatives such as tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and/or derivatives thereof; erythorbic acid and derivatives thereof; sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfite; thiotaurine, hypotaurine; It is mentioned as. Preferred reducing agents include thioglycolic acid, cysteine, cysteamine, and the like. Preferred examples of the oxidizing agent include aqueous hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate.

Antibacterial agents or antiseptics include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben, and butylparaben; phenoxyethanol; 1,2-pentanediol, 1,2-hexanediol, 1,2-octane 1,2-alkanediols such as diols; alkylglyceryl ethers such as 2-ethylhexylglyceryl ether (ethylhexylglycerin); salicylic acid; sodium benzoate; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; linium urea; dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, benzalkonium chloride, benzethonium chloride, sorbic acid, chlorhexidine, glucon Chlorhexidine acid, halocarban, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, phenylphenol sodium; phenylethyl alcohol, photosensitizers, antibacterial zeolite, silver ion is preferable, but when used as an antibacterial agent or antiseptic for the purpose of preserving, from the viewpoint of safety of cosmetics or external skin preparations, phenoxyethanol; 1,2-pentanediol, 1,2-hexane 1,2-alkanediols such as diols and 1,2-octanediol; alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether are more preferably used.

Chelating agents include edetate (ethylenediaminetetraacetate) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediamine triacetate such as HEDTA3Na; pentetate (diethylenetriaminepentaacetate); phytic acid; Phosphonic acid and salts such as its sodium salt; Sodium oxalate; Polyamino acids such as polyaspartic acid and polyglutamic acid; Sodium polyphosphate, sodium metaphosphate, phosphoric acid; Sodium citrate, citric acid, alanine, dihydroxyethylglycine , gluconic acid, ascorbic acid, succinic acid and tartaric acid are preferred. pH adjusters, acids, and alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, and monoethanol. Amines, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxide Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferred.

Powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluoroapatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metal soap (e.g. zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, red iron oxide, yellow iron oxide, black iron oxide, ultramarine blue, Prussian blue, carbon black, titanium oxide, fine and ultrafine titanium oxide, zinc oxide , fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silicic anhydride), mica titanium, fish scale foil, boron nitride, photochromic pigment, synthetic fluorine phlogopite, fine particle composite powder, gold, aluminum, etc. Inorganic powders of various sizes and shapes, and these are treated with various surface treatment agents such as silicone such as hydrogen silicone, cyclic hydrogen silicone, or other silane or titanium coupling agents to make them hydrophobic or Inorganic powder such as hydrophilized powder; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene-acrylic acid copolymer resin powder, polyester powder, benzoguanamine resin powder, polyethylene terephthalate・Organic powders and surface-treated powders of various sizes and shapes, such as polymethyl methacrylate layered powder, polyethylene terephthalate/aluminum/epoxy layered powder, urethane powder, silicone powder, Teflon (registered trademark) powder, etc., organic and inorganic Composite powders are preferred. Examples of inorganic salts include sodium chloride-containing salts such as common salt, common salt, rock salt, sea salt, and natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum/potassium sulfate (alum), aluminum/ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na, 2Na, and 3Na phosphate, phosphoric acid Potassiums, calcium phosphates, and magnesium phosphates are preferred.

UV absorbers include para-aminobenzoic acid, para-aminobenzoic acid monoglycerol ester, N,N-dipropoxy para-aminobenzoic acid ethyl ester, N,N-diethoxy para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester. Benzoic acid-based UV absorbers such as esters, N,N-dimethylpara-aminobenzoic acid butyl ester, N,N-dimethylpara-aminobenzoic acid ethyl ester; Anthranilic acid-based UV absorbers such as homomenthyl-N-acetylanthranilate; Salicylic acid and salicylic acid UV absorbers such as sodium salts thereof, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate; octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl -2,5-diisopropylcinnamate, ethyl-2,4-diisopropylcinnamate, methyl-2,4-diisopropylcinnamate, propyl-p-methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxy Cinnamate, 2-ethylhexyl p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (cinoxate), cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenyl Cinnamic acid-based UV absorbers such as cinnamate, 2-ethylhexyl α-cyano-β-phenylcinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxycinnamate, ferulic acid and derivatives thereof;2, 4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy- 4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4' -phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone, and other benzophenone UV absorbers; 3-(4'-methylbenzylidene)-d, l-camphor, 3-benzylidene-d,l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5-methylphenylbenzotriazole; 2-(2'-hydroxy-5'- t-octylphenyl)benzotriazole; 2-(2′-hydroxy-5′-methylphenylbenzotriazole; dibenzalazine; dianisoylmethane; 5-(3,3-dimethyl-2-norbornylidene)-3-pentane-2- dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane; octyl triazone; urocanic acid derivatives such as urocanic acid and ethyl urocanate; 2-(2'-hydroxy-5'-methylphenyl)benzotriazole , 1-(3,4-dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, hydantoin derivatives such as 2-ethylhexyl dimethoxybenzylidene dioxoimidazolidinepropionate, phenylbenzimidasozole sulfonic acid, tele Pharylidendicanefursulfonic acid, drometrisol trisiloxane, methyl anthranilate, rutin and its derivatives, oryzanol and its derivatives are preferred.

Examples of vitamins and derivatives thereof include vitamin A such as retinol, retinol acetate, and retinol palmitate; flavin adenine dinucleotide, cyanocobalamin, folic acids, nicotinic acids such as nicotinamide and benzyl nicotinate, B vitamins such as choline; vitamin Cs such as ascorbic acid and salts thereof such as sodium; vitamin D; Vitamin E such as β, γ, δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphate salts such as ascorbyl phosphate sodium salt and ascorbyl phosphate magnesium salt, ascorbic acid tetra Ascorbic acid fatty acid esters such as isopalmitate, ascorbyl stearate, ascorbyl palmitate, and ascorbyl dipalmitate, ascorbic acid alkyl ethers such as ascorbyl ethyl ether, ascorbic acid glucosides such as ascorbic acid-2-glucoside, and fatty acid esters thereof , ascorbic acid derivatives such as tocopheryl ascorbyl phosphate; vitamin derivatives such as tocopherol nicotinate, tocopheryl acetate, tocopherol linoleate, tocopherol ferulate, tocopherol phosphate, tocotrienols, and other various vitamin derivatives are preferred. It is mentioned as.

Antiphlogistic and anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhizic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramine hydrochloride, chlorpheniramine maleate; and plant extracts such as mugwort leaf extract are preferred. Hair growth agents, blood circulation promoters, and stimulants include plant extracts and tinctures such as assembly extract, capsicum tincture, ginger tincture, ginger extract, and cantharis tincture; , borneol, cyclanderate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthine, γ-oryzanol, cepharanthine, vitamin E and derivatives such as tocopherol nicotinate and tocopherol acetate, γ-oryzanol, nicotinic acid and nicotinamide, benzyl nicotinate Derivatives such as ester-inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, flavanonol derivatives, stigmasterol or stigmastanol and its glycosides, and minoxidil are preferred. It is mentioned as. Preferred examples of hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone, and the like. Other medicinal agents such as anti-wrinkle agents, anti-aging agents, tightening agents, cooling agents, warming agents, wound healing promoting agents, stimulating agents, analgesics, and cell activators include retinols, retinoic acids, and retinoin. tocopheryl acid; lactic acid, glycolic acid, gluconic acid, fruit acid, salicylic acid and derivatives such as glycosides and esters thereof, hydroxycapric acid, long-chain α-hydroxy fatty acids, α- or long-chain α-hydroxy fatty acid cholesteryl β-hydroxy acids and their derivatives; γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine, etc. and their derivatives; , astaxanthin, lutein, α-lipoic acid, platinum nanocolloids, antioxidants and active oxygen scavengers such as fullerenes; catechins; flavones such as quercetin; isoflavones; gallic acid and ester sugar derivatives; Polyphenols such as anthocyanidins, chlorogenic acid, and apple polyphenols; derivatives such as rutin and glycosides; derivatives such as hesperidin and glycosides; lignan glycosides; shogaol, gingerol; menthol, camphor, cedrol and other flavoring substances and derivatives thereof; capsaicin, vanillin and the like and their derivatives; insect repellents such as diethyltoluamide; mentioned.

Plant/animal/microorganism extracts include iris extract, angelica keiskei extract, asunaro extract, asparagus extract, avocado extract, amacha extract, almond extract, altea extract, arnica extract, aloe extract, apricot extract, apricot kernel extract, and ginkgo biloba extract. , Inchko extract, Fennel extract, Turmeric extract, Oolong tea extract, Arctic extract, Age extract, Echinashi leaf extract, Tripod extract, Scutellaria root extract, Phellodendron bark extract, Coptis extract, Barley extract, Panax ginseng extract, Hypericum extract, Dead nettle extract, Ononis extract , Dutch mustard extract, orange extract, seawater dried matter, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, hydrolyzed silk, kakkon extract, chamomile extract, oil-soluble chamomile extract, carrot extract, wormwood extract, oat extract, karkade extract, licorice extract, oil-soluble licorice extract, kiwi extract, kiwi extract, cloud ear extract, cinchona extract, cucumber extract, paulownia leaf extract, guanosine, guava extract, kujin extract, gardenia extract, kumazasa extract, clara extract, walnut Extract, Chestnut extract, Grapefruit extract, Clematis extract, Black rice extract, Brown sugar extract, Black vinegar, Chlorella extract, Mulberry extract, Gentian extract, Gennoshoko extract, Black tea extract, Yeast extract, Koboku extract, Coffee extract, Burdock extract, Rice extract, Rice Fermented extract, rice bran fermented extract, rice germ oil, comfrey extract, collagen, cowberry extract, rhinoceros extract, rhinoceros extract, rhinoceros extract, saffron extract, salvia extract, soapwort extract, bamboo grass extract, hawthorn extract, sansha extract, Japanese pepper extract, shiitake extract, reed extract, licorice extract, perilla extract, linden extract, meadowsweet extract, jatoba extract, peony extract, ginger extract, calamus root extract, white birch extract, white fungus extract, horsetail extract, stevia extract, fermented stevia, Nishikawayanagi extract, Ivy Extract, Hawthorn Extract, Sambucus Extract, Yarrow Extract, Peppermint Extract, Sage Extract, Mallow Extract, Cnidium Extract, Assembly Extract, Rhubarb Extract, Rhubarb Extract, Soybean Extract, Sunflower Extract, Thyme Extract, Dandelion Extract, Ground Clothing extract, tea extract, clove extract, cinnamon extract, chimp extract, tea tree oil, sweet tea extract, capsicum extract, angelica root extract, calendula officinalis extract, tonin extract, spruce extract, dokudami extract, tomato extract, natto extract, carrot extract, garlic extract, wild rose extract , hibiscus extract, Bakumondou extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, hikiokoshi extract, bisabolol, cypress extract, bifidobacterium extract, loquat extract, coltsfoot extract, butterbur extract, sagebrush extract, butcher Bloom extract, Grape extract, Grape seed extract, Propolis, Loofah extract, Safflower extract, Peppermint extract, Bodaiju extract, Botan extract, Hop extract, Mica squid extract, Pine extract, Horse chestnut extract, Asian skunk cabbage extract, Soap extract, Melissa extract, Mozuku extract , peach extract, cornflower extract, eucalyptus extract, saxifrage extract, yuzu extract, lily extract, coix seed extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, litchi extract, lettuce extract, lemon extract, forsythia extract , astragalus extract, rose extract, rosemary extract, Roman chamomile extract, royal jelly extract, burnet extract and the like are preferred.

Examples of antipruritic agents include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitors and the like. Examples of exfoliating/dissolving agents include salicylic acid, sulfur, resorcinol, selenium sulfide, pyridoxine, and the like. Examples of antiperspirants include aluminum chlorohydroxy, aluminum chloride, zinc oxide, and zinc paraphenolsulfonate. Examples of cooling agents include menthol and methyl salicylate. Examples of astringents include citric acid, tartaric acid, lactic acid, aluminum/potassium sulfate, and tannic acid. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease, and the like. Preferred nucleic acids include ribonucleic acid and its salts, deoxyribonucleic acid and its salts, and disodium adenosine triphosphate.

Fragrances include acetylcedrene, amyl cinnamaldehyde, allyl amyl glycolate, β-ionone, iso-e-super, isobutylquinoline, iris oil, iron, indole, ylang-ylang oil, undecanal, undecenal, γ-undecenal, Estragole, eugenol, oakmoss, opoponax resinoid, orange oil, eugenol, aurantiol, galacsolid, carvacrol, L-carvone, camphor, cannon, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile , isobornyl acetate, geranyl acetate, dimethylbenzyl carbyl acetate, styraryl acetate, cedryl acetate, terpinel acetate, p-t-butylcyclohexyl acetate, betiveryl acetate, benzyl acetate, linalyl acetate, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, Cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromyrcenol, jasmine absolute, jasmine lactone, cis-jasmone, citral, citronenol, citronellal, cinnamon bark oil, 1,8-cineole, cinnamaldehyde, styrax Resinoids, cedarwood oil, cedren, cedrol, celery seed oil, thyme oil, damascone, damascenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, tripral, nerol, nonanal, 2,6-nonadienol, nonalactone, patchouli Alcohol, vanilla absolute, vanillin, basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, petitgrain oil, hexylcinnamaldehyde, cis-3-hexenol, peruvian balsam, vetiver oil, vetiverol , peppermint oil, pepper oil, heliotropine, bergamot oil, benzyl benzoate, borneol, myresinoid, musk ketone, methylnonylacetaldehyde, γ-methylionone, menthol, L-menthol, L-mentone, eucalyptus oil, β-ionone, lime oil , lavender oil, D-limonene, linalool, lyral, lyreal, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils, synthetic and natural fragrances, and various compounded fragrances are preferred.

Colorants/colorants/dyes/pigments include Brown No. 201, Black No. 401, Purple No. 201, Purple No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 202, Blue No. 203 and Blue No. 204. , Blue No. 205, Blue No. 403, Blue No. 404, Green No. 3, Green No. 201, Green No. 202, Green No. 204, Green No. 205, Green No. 3, Green No. 401, Green No. 402, Red No. 102, Red 104-1, red 105-1, red 106, red 2, red 3, red 201, red 202, red 203, red 204, red 205, red 206, red 207 , Red No. 208, Red No. 213, Red No. 214, Red No. 215, Red No. 218, Red No. 219, Red No. 220, Red No. 221, Red No. 223, Red No. 225, Red No. 226, Red No. 227, Red 228, Red 230-1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503 , Red No. 504, Red No. 505, Red No. 506, Orange No. 201, Orange No. 203, Orange No. 204, Orange No. 205, Orange No. 206, Orange No. 207, Orange No. 401, Orange No. 402, Orange No. 403, Yellow 201, yellow 202-1, yellow 202-2, yellow 203, yellow 204, yellow 205, yellow 4, yellow 401, yellow 402, yellow 403-1, yellow 404, yellow Legal dyes such as No. 405, Yellow No. 406, Yellow No. 407, and Yellow No. 5; Other acid dyes such as Acid Red 14; Basic dyes such as Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, and Arianor Straw Yellow; HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydroxypropylamino-3-nitrophenol, N,N'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine, HC Blue 2, Basic Blue 26 and other nitro dyes; Disperse dyes; Inorganic white pigments such as titanium dioxide and zinc oxide; Inorganic red pigments such as iron oxide (red iron oxide) and iron titanate; Inorganic brown pigments such as γ-iron oxide; Inorganic yellow pigments such as yellow iron oxide and ocher Inorganic black pigments such as black iron oxide and low order titanium oxide; Inorganic purple pigments such as mango violet and cobalt violet; Inorganic green pigments such as chromium oxide, chromium hydroxide and cobalt titanate; Inorganic blue pigments such as titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, colored titanium oxide-coated mica, bismuth oxychloride, fish scale foil and other pearl pigments; aluminum powder, copper powder, gold, etc. Metal powder pigments; anthraquinones such as astaxanthin and alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, carthamine, quercetin, crocin, chlorophyll, curcumin, cochineal, naphthoquinones such as shikonin, bixin, flavones, betacyanidins, Natural pigments/dyes such as henna, hemoglobin, lycopene, riboflavin, rutin; p-phenylenediamine, toluene-2,5-diamine, o-, m-, or p-aminophenol, m-phenylenediamine, 5-amino- Oxidative dye intermediates and couplers such as 2-methylphenol, resorcinol, 1-naphthol, 2,6-diaminopyridine and salts thereof; autoxidative dyes such as indoline; and dihydroxyacetone are preferred.

Preferable examples of water include ordinary water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, ionized water, and cluster water.

In addition to these, the Standards for Cosmetic Ingredients, Standards for Ingredients by Cosmetic Type, List of Ingredients Displayed by the Japan Cosmetic Industry Association, INCI Dictionary (The International Cosmetic Ingredient Dictionary and Handbook), Standards for Quasi-drug Ingredients, Japanese Pharmacopoeia, Pharmaceutical Additives Ingredients listed in standards, food additive standards, etc., and in Japanese and foreign patent publications and patent publication publications (including publication publications and republication) that belong to the classification of A61K7 and A61K8 in the international patent classification IPC Known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as those described, can be contained in known combinations and blending ratios and blending amounts.

Types of the cosmetics of the present invention include hair cosmetics, skin cosmetics, make-up cosmetics, aromatic cosmetics, body cosmetics, skin preparations for external use such as ointments, and the like. The cosmetic of the present invention can be produced according to ordinary methods.

To explain the types of the cosmetic composition or skin external preparation of the present invention in more detail, hair cosmetic compositions include shampoos such as oil shampoos, cream shampoos, conditioning shampoos, dandruff shampoos, hair color shampoos, rinse-integrated shampoos, and the like. Rinse, treatment, hair pack, hair foam, hair mousse, hair spray, hair mist, hair wax, hair gel, water grease, set lotion, color lotion, hair tonic, hair liquid, pomade, tick, hair cream, hair blow, split ends coat , hair oils, permanent wave agents, straight permanent agents, oxidative hair dyes, hair bleach, hair color pretreatments, hair color aftertreatments, perm pretreatments, perm aftertreatments, hair manicures, and hair growth agents.

Skin cosmetics include lotions such as softening lotion, astringent lotion, cleansing lotion, multi-layer lotion; emollient lotion, moisturizing lotion, milky lotion, nourishing lotion, nourishing milk, skin moisturizer, moisturizer - Emulsions, massage lotions, cleansing lotions, protective emulsions, sun protection, sun protectors, UV care milk, sunscreens, make-up lotions, keratin smoothers, elbow lotions, hand lotions, body lotions, etc.; emollient creams, nourishing creams, Nourishing cream, vanishing cream, moisturizing cream, night cream, massage cream, cleansing cream, makeup cream, base cream, pre-makeup cream, sunscreen cream, suntan cream, depilatory cream, deodorant cream, shaving cream, exfoliating Creams such as creams; Gels such as moisture gels; Essences such as moisturizing essences, whitening essences and UV protection essences; Liposome cosmetics such as liposome serums and lotions; Face wash such as cleansing foam, cleansing cream, cleansing milk, cleansing lotion, cleansing gel, cleansing oil, cleansing mask, cleansing powder, facial cleansing powder; Soaps such as shaving soaps and synthetic toilet soaps are preferred.

Preferable examples of make-up cosmetics include powders/powder powders, foundations, lipsticks, lip glosses, blushers, eyeliners, mascara, eyeshadows, eyebrows, eyebrows, nail enamels, enamel removers, and nail treatments. .

Perfume, perfume, parfum, eau de parfum, eau de toilette, eau de cologne, paste perfume, fragrant powder, perfumed soap, body lotion, and bath oil are preferable examples of fragrant cosmetics.

Body cosmetics include body cleansers such as body shampoo, deodorant cosmetics such as deodorant lotion, deodorant powder, deodorant spray, and deodorant sticks, decolorizers, hair removal agents, bath agents, and insect repellent sprays. Repellers are preferred.

In addition, external skin preparations can be used in dosage forms such as ointments, patches, lotions, liniments, and liquid coatings. It can also be used as an intraoral cosmetic such as toothpaste and mouthwash.

Formulations of the cosmetic or external preparation for skin of the present invention include emulsions such as oil-in-water (O/W) type, water-in-oil (W/O) type, W/O/W type, and O/W/O type. type cosmetics, oil-based cosmetics, solid cosmetics, liquid cosmetics, paste-type cosmetics, stick-type cosmetics, volatile oil-type cosmetics, powder-type cosmetics, jelly-type cosmetics, gel-type cosmetics, paste-type cosmetics Preferable dosage forms include cosmetics, emulsified polymer type cosmetics, sheet cosmetics, mist cosmetics, and spray cosmetics.

The present invention will be described in more detail by the following examples, but the present invention is not limited to these.

Lotions containing the components (A) to (D) of the present invention with the compositions shown in Tables 1 to 3 were prepared by the following method. The initial dispersibility, transparency, and dispersion stability of the resulting lotion were evaluated by the following methods, and the results are shown in the lower column of each table.

<Preparation method>
Components (A), (B) and (C) were previously stirred and mixed at 80° C. to prepare a polyhydric alcohol dispersion. The resulting polyhydric alcohol dispersion was added with stirring to an aqueous solution of methylparaben and component (D) which had been heated and dissolved at 80°C, and stirred with a homomixer (75°C, 5000 rpm, 15 minutes). , cooled.

<Initial Dispersibility>
The dispersion state of the obtained lotion immediately after preparation was visually observed, and the initial dispersibility was evaluated according to the following evaluation criteria.

○: uniformly dispersed ×: not uniformly dispersed

<Transparency>
The transmittance of the lotion was measured using a spectrophotometer (cell thickness 1 cm, wavelength 600 nm). In addition, the lotion was placed in a glass bottle with a diameter of 3.5 cm, the appearance was visually observed from the side, and the transparency was evaluated according to the following evaluation criteria.

○: Behind the liquid can be seen through △: Behind the liquid can be slightly seen through ×: Behind the liquid cannot be seen through

<Dispersion stability>
The obtained lotion was subjected to a storage stability test at 50° C./1 month, and dispersion stability was evaluated according to the following evaluation criteria.

○: Evenly dispersed even after storage △: Almost evenly dispersed even after storage ×: Not evenly dispersed after storage, or sedimentation occurs

From the results in Tables 1 to 3, compared to lotions (Comparative Examples 1 and 2) that did not contain component (B) or (C), lotions within the composition range of the present invention had transparency and dispersibility. It was found to be excellent in stability. Further, when the ratio of component (A1) in component (A) is high, initial dispersion cannot be performed (Comparative Example 3), and transparency and dispersion stability are excellent when the PC content in component (A2) is high. was found (Examples 13 and 15).

Cosmetics described below were prepared. The obtained cosmetic had excellent moisturizing properties and permeation, prevented fine wrinkles and rough skin, and made the skin look plump and bright. In addition, when used on the hair, it was excellent in moistness and manageability. Furthermore, the make-up cosmetic was excellent in moisturizing properties, adhesion to the skin, and smoothness.

Example 16 Moisturizing Lotion Component Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.02
Hydrogenated lecithin (PC content 97%) 0.05
Lecithin (PC content 92%) 0.01
Sucrose Laurate 0.05
PEG-60 hydrogenated castor oil 0.02
BG 2.0
Glycerin 3.0
Part B Purified water 40.0
Part C Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Glucosylceramide 0.5
Tremoist-TP (Nippon Fine Chemicals) 0.1
EDTA-2Na 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. After cooling, the pre-mixed part C was added to obtain a uniform liquid.

Example 17 Moisturizing lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.04
Hydrogenated lecithin (PC content 97%) 0.09
Lecithin (PC content 92%) 0.01
POE (20) Phytosterol 0.1
Polyglyceryl-6 laurate 0.2
Polyglycerin-10 1.0
Diglycerin 2.0
Glycerin 8.0
1,2-Pentanediol 4.0
Plandool-LG2 (Nippon Fine Chemicals) 0.01
Plandool-ISS (Nippon Fine Chemicals) 0.01
Part B Purified water 50.0
Part C maltitol liquid 1.0
Betaine 0.5
α-glucan oligosaccharide 0.1
Sodium hyaluronate 0.5
Tuberose polysaccharide 0.01
Hydroxypropyl methylcellulose stearoxy ether 0.05
(Acrylates/C10-30 alkyl acrylate) crosspolymer 0.05
Arginine 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, they were dispersed using a high-pressure emulsifier (Microfluidizer manufactured by Mizuho Kogyo Co., Ltd.). After cooling, the pre-mixed Part C was added to obtain a uniform liquid.

Example 18 Moisturizing Lotion Component Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.04
Hydrogenated lecithin (PC content 97%) 0.09
Lecithin (PC content 92%) 0.01
Phytopresome MEL (Nippon Fine Chemicals) 1.0
Polyglyceryl-10 Laurate 1.0
BG 5.0
Glycerin 10.0
PG 5.0
Part B Purified water 40.0
Part C Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
PEG/PPG/polybutylene glycol-8/5/3 glycerin 0.5
Xanthan gum 0.05
Glucosyltrehalose 0.5
Polyquaternium-51 0.5
Hydrolyzed Yeast Extract 1.0
Licorice extract 0.05
Aloe extract 0.05
Souhakuhi Extract 0.2
Inulin-SC (Nippon Fine Chemical) 2.0
Pentetate pentasodium 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. After cooling, the pre-mixed part C was added to obtain a uniform liquid.

Example 19 Moisturizing lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.04
Hydrogenated lecithin (PC content 97%) 0.09
Lecithin (PC content 92%) 0.01
Polysorbate 20 2.0
Glycerin 8.0
Hexylene glycol 5.0
Lysolecithin 0.03
Phytopresome Cera236 (Nippon Fine Chemicals) 0.05
Part B Purified water 60.0
Part C Hydrolyzed Collagen 0.05
Hydrolyzed sodium hyaluronate 0.05
Citric acid 0.01
Na citrate 0.09
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Sodium pyrrolidonecarboxylate 0.1
Inositol 0.2
Arginine 0.1
Alanine 0.1
Betaine 0.1
EDTA-2Na 0.05
Phenoxyethanol 0.4
Purified water Amount that totals 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a propeller (500 rpm) to prepare an aqueous dispersion. After cooling, the pre-mixed part C was added to obtain a uniform liquid.

Example 20 Moisturizing lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.08
Hydrogenated lecithin (PC content 97%) 0.18
Lecithin (PC content 92%) 0.02
LP70H (Nippon Fine Chemicals) 0.05
Glyceryl Caprate 1.0
Propanediol 5.0
Glycerin 10.0
1,2-Pentanediol 10.0
Phytopresome Lipo-Q (Nippon Fine Chemicals) 0.05
Phytopresome Asta (Nippon Fine Chemicals) 0.05
LUSPLAN PI-DA (Nippon Fine Chemicals) 0.05
Plandool-DP (Nippon Fine Chemicals) 0.05
Phytosterol 0.05
Tocopherol 0.02
Part B Purified water 60.0
Part C Mannitol 1.0
PEG-30 1.0
Hydrolyzed Collagen 0.1
Urea 0.1
Chondroitin sulfate Na 0.05
Hydroxyethyl cellulose 0.03
Carboxyvinyl polymer 0.05
Sorbitol 0.5
Phenoxyethanol 0.2
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, they were dispersed using a high-pressure emulsifier (Microfluidizer manufactured by Mizuho Kogyo Co., Ltd.). After cooling, the pre-mixed Part C was added to obtain a uniform liquid.

Example 21 Moisturizing lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.15
Hydrogenated lecithin (97% PC content) 0.75
Lecithin (PC content 92%) 0.1
Phytopresome MEL (Nippon Fine Chemicals) 1.5
PEG-40 hydrogenated castor oil 0.5
DPG 3.0
Glycerin 5.0
1,2-Pentanediol 2.0
Part B Purified water 60.0
Part C Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Inulin-SC (Nippon Fine Chemical) 5.0
Xanthan gum 0.05
Suizenjinori polysaccharide 0.01
Phytic acid 0.1
Phenoxyethanol 0.4
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, they were dispersed using a high-pressure emulsifier (Microfluidizer manufactured by Mizuho Kogyo Co., Ltd.). After cooling, the pre-mixed Part C was added to obtain a uniform liquid.

Example 22 Moisturizing lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.15
Hydrogenated lecithin (97% PC content) 0.75
Lecithin (PC content 92%) 0.1
Polysorbate 20 0.5
Polyglyceryl-10 myristate 0.5
Polyglycerin-10 1.0
Glycerin 8.0
1,2-Pentanediol 5.0
Neosolue-DiSM (Nippon Fine Chemicals) 0.04
Plandool-LG2 (Nippon Fine Chemicals) 0.01
Part B Purified water 50.0
Part C Erythritol 1.0
Betaine 0.5
α-glucan oligosaccharide 0.1
Sodium hyaluronate 0.1
Tremoist-SL (Nippon Fine Chemical) 1.0
Hydroxypropyl methylcellulose stearoxy ether 0.05
Carboxyvinyl polymer 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, they were dispersed using a high-pressure emulsifier (Microfluidizer manufactured by Mizuho Kogyo Co., Ltd.). After cooling, the pre-mixed Part C was added to obtain a uniform liquid.

Example 23 Whitening lotion Component Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.08
Hydrogenated lecithin (PC content 97%) 0.18
Lecithin (PC content 92%) 0.02
Phytosterol 0.05
Polysorbate 80 0.5
Sucrose Laurate 0.8
Glycerin 8.0
PG 5.0
Part B 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Arbutin (Nippon Fine Chemicals) 1.0
Purified water 30.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Ethanol 3.0
Inulin-SC (Nippon Fine Chemical) 2.0
Methylgluceth-10 2.0
Glycyrrhizic acid 2K 0.05
Tremoist-TP (Nippon Fine Chemicals) 0.02
Xanthan gum 0.03
Phenoxyethanol 0.2
Methylparaben 0.15
Edetate Na 0.2
Citric acid 0.1
Na citrate Amount that makes the pH 4.5 Part C Purified water Amount that makes the total 100 －－－－－－－－－－－－－－－－－－－－－－－－－－－－－－ －－－－－－－－－
(Preparation method)
Part B was mixed to prepare a viscous liquid. Part A and part C were each heated to 70° C., and part A was added while stirring part C with a homomixer (7000 rpm) to prepare an aqueous dispersion. After cooling, the pre-mixed part B was added to obtain a uniform liquid.

Example 24 Whitening lotion Component Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.08
Hydrogenated lecithin (PC content 97%) 0.18
Lecithin (PC content 92%) 0.02
Polysorbate 20 0.02
Glycolipid (Ceramela-HG) 0.5
Glycerin 8.0
Oryzanol 0.1
Part B Tranexamic acid (Nippon Fine Chemicals) 2.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Ascorbic acid 2-glucoside 1.0
Phytic acid 0.30
Purified water 20.0
Scutellaria root extract 0.2
Peony extract 0.2
Tripropylene glycol 2.0
DPG 2.0
Maltose 1.0
Carbomer 0.01
Glutamic acid 0.2
Phenoxyethanol 0.2
Methylparaben 0.15
Citric acid 0.1
Na citrate Appropriate amount Part C Purified water Total amount to be 100－－－－－－－－－－－－－－－－－－－－－－－－－－ ----
(Preparation method)
Part B was mixed to prepare a viscous liquid. Each of parts A and C was heated to 70° C., and part A was added while stirring part C with a homomixer (7000 rpm) to prepare an aqueous dispersion. After cooling, the pre-mixed part B was added to obtain a uniform liquid.

Example 25 Gel lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Glycerin 10.0
1,2-Pentanediol 5.0
Sorbitol liquid (70%) 5.0
Polyglyceryl-10 Laurate 0.4
Polyglyceryl-6 laurate 0.2
Part B Niacinamide 1.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Neosolue-Aqua (Nippon Fine Chemicals) 1.0
Diglycerin 3.0
Tripropylene glycol 3.0
PEG-60 3.0
Purified water 10.0
Part C Pullulan 0.2
Ethylhexylglycerin 0.2
Polymethacryloyllysine 0.05
Tremoist-SL (Nippon Fine Chemical) 1.0
Locust bean gum 0.03
Hydroxyethyl cellulose 0.05
Xanthan gum 0.05
Sodium hyaluronate 0.01
Carbomer 0.06
K hydroxide 0.05
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 70°C and dispersed uniformly. Part C was mixed, stirred well, homogenized and heated to about 70°C. Part B was stirred with a propeller to prepare a mixture. Part C was added to part A, the mixture was stirred at about 70°C using a homomixer, cooled to about 40°C, and the mixture of part B was added.

Example 26 Clear gel
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Glycerin 5.0
1,2-Hexanediol 3.0
PPG-6 decyltetradeceth-30 0.2
POE (20) Phytosterol 0.3
Phytopresome MEL (Nippon Fine Chemicals) 0.8
Purified water 40.0
Part B PEG-4M 0.2
Methylgluceth-10 1.0
Pyridoxine hydrochloride 0.05
Ethylhexylglycerin 0.2
Phenoxyethanol 0.4
Tremoist-TP (Nippon Fine Chemicals) 0.01
Hydrolyzed Collagen 0.01
Purified water Total amount to be 100 Part C Pentetate 5Na 0.05
(dimethyltaurate ammonium acrylate/vinylpyrrolidone) copolymer 0.05
(Acrylates/C10-30 alkyl acrylate) crosspolymer 0.15
Arginine 0.25
Purified water 20.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was stirred with a propeller to prepare a nanovesicle solution. Part C was mixed into a viscous liquid. Part B was mixed to form a uniform liquid. Part A and part B were added to part C and made uniform.

Example 27 Scalp Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Phytosterol 0.01
Sucrose Laurate 1.5
Glycerin 6.0
1,2-hexanediol 1.0
Part B Purified water 50.0
Part C Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Tocopherol Acetate 0.05
Menthol 0.1
Betaine 0.2
Assembly extract 0.1
Tamasaki Tsutsurugi Root Extract 0.003
Hinokitiol 0.1
PCA-Na 0.1
Carbomer 0.01
K hydroxide 0.01
Pentetate pentasodium 0.05
Methylparaben 0.1
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare a nanovesicle solution. After cooling, the pre-mixed part C was added to obtain a uniform liquid.

Example 28 Hair restorer
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Glycerin 3.0
1,2-Pentanediol 5.0
Phytopresome MEL (Nippon Fine Chemicals) 1.0
Polysorbate-20 0.1
Part B Neosolue-Aquilio (Nippon Fine Chemicals) 0.5
DPG 2.0
Lactic acid 0.1
Tremoist-TP (Nippon Fine Chemicals) 0.01
Purified water 50.0
Part C Ethanol 10.0
Menthol 0.1
Menthyl glyceryl ether 0.15
Panthenyl ethyl ether 0.2
Camphor 0.1
Cordyceps Extract 1.0
Assembly Extract 1.0
Loquat Leaf Extract 1.0
Hydrolyzed hyaluronic acid 0.02
Sodium cyclic lysophosphatidate 0.001
Capsicum extract 0.01
Betaine 0.3
Trehalose 0.2
Cymene-5-ol 0.1
Tocopherol Acetate 0.05
β-Glycyrrhetinic acid 0.05
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a propeller (500 rpm) to prepare a nanovesicle liquid. After cooling, the pre-mixed part C was added to obtain a uniform liquid.

Example 29 Whitening emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Plandool-H (Nippon Fine Chemicals) 1.0
Plandool-LG3 (Nippon Fine Chemicals) 1.0
Plandool-DP (Nippon Fine Chemicals) 1.0
LUSPLAN DD-DA5 (Nippon Fine Chemical) 0.2
LUSPLAN DD-DA7 (Nippon Fine Chemical) 0.2
Cetyl ethylhexanoate (Nippon Fine Chemicals) 7.0
Diethylhexyl succinate (Nippon Fine Chemicals) 3.0
Cetanol 1.2
Myristyl alcohol 2.0
Oleyl alcohol 1.0
Part B Stealoxy hydroxypropyl methylcellulose 0.1
Xanthan gum 0.1
Purified water 20.0
Part C Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Phytocompo-C (Nippon Fine Chemicals) 1.0
1,2-Pentanediol 3.0
Glycerin 8.0
Polyglyceryl-10 Laurate 0.5
Part D 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Tranexamic acid (Nippon Fine Chemicals) 2.0
Purified water 5.0
Part E Phenoxyethanol 0.2
Methylparaben 0.15
Phytic acid 0.5
Citric acid 0.1
Sodium citrate Amount that makes pH 4.5 Purified water Amount that makes the total 100 －－－－－－－－－－－－－－－－－－－－－－－－－ -----
(Preparation method)
Part A and part E were each heated to about 70° C. and dissolved uniformly. Part B was stirred to form a viscous liquid. Part C was heated to about 70° C. and evenly dispersed. After adding part A while stirring part C with a homodisper, part E was added while stirring. Part D and part B were added at about 50° C. and dissolved uniformly by stirring.

Example 30 Emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Glycerin 3.0
1,2-Pentanediol 5.0
BG 3.0
LP70H (Nippon Fine Chemicals) 0.1
Phytocompo-PP (Nippon Fine Chemicals) 1.5
Polysorbate 80 0.5
Part B Triethylhexanoin (Nippon Fine Chemicals) 3.0
LUSPLAN SR-DM4 (Nippon Fine Chemical) 0.5
Hydrogenated polyisobutene 3.5
Isododecane 1.5
Cetostearyl alcohol 1.0
Arachyl alcohol 0.1
Jojoba Alcohol 3.0
chimyl alcohol 0.3
Serachyl alcohol 0.1
Hexyldecanol 0.5
Part C BG 5.0
(Hydroxyethyl acrylate/Na acryloyldimethyltaurate) copolymer
0.2
Tremoist-TP (Nippon Fine Chemicals) 0.03
Carbomer 0.1
Purified water 30.0
Part D Neosolue-Aqua (Nippon Fine Chemicals) 0.5
Polyquaternium-51 1.0
Ascorbyl glucoside 1.0
Potassium hydroxide 0.2
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C is mixed and stirred to viscosity. After adding part B while stirring part A with a homodisper, part D was added and emulsified. Upon cooling to about 50°C, add Part C, stir and cool to about 40°C.

Example 31 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Sugar squalane 10.0
Stearic acid 1.0
Plandool-ISS (Nippon Fine Chemicals) 1.0
Plandool-SUN (Nippon Fine Chemicals) 1.0
Jojoba Oil 3.0
behenyl alcohol 2.0
PEG-20 glyceryl isostearate 1.0
Olive oil fatty acid sorbitan 0.8
Polyglyceryl-10 oleate 1.0
Part B Acrylic acid-alkyl methacrylate copolymer 0.1
K hydroxide 0.07
(acryloyldimethyltaurate ammonium/
Beheneth methacrylate-25) Crosspolymer 0.2
Tremoist-SL (Nippon Fine Chemical) 1.0
Purified water 20.0
Hydrolyzed poly γ-glutamic acid K 0.1
Sodium polyglutamate 0.1
Oligopeptide-24 0.05
Part C Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Glyceryl caprate 0.1
Decyl glucoside 0.05
Glycerin 9.0
1,2-Pentanediol 10.0
PEG-8 5.0
PEG-2M 2.0
Ethylhexylglyceryl 0.8
DPG 1.5
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to a viscous liquid. While stirring part C with a homomixer, part A was added and emulsified. Upon cooling to about 50°C, add Part B, stir and cool to about 40°C.

Example 32 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Olive oil 1.5
Shea butter 1.0
Dimethicone 10 cSt 1.0
Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 3.0
Neosolue-DiSM (Nippon Fine Chemicals) 5.0
LUSPLAN DD-DHR (Nippon Fine Chemicals) 1.0
LUSPLAN DD-IS (Nippon Fine Chemicals) 1.0
Cholesteryl 12-hydroxystearate 0.1
Cetearyl glucoside 1.2
behenyl alcohol 1.5
Ascorbyl Tetrahexyldecanoate 7.0
Cetanol 2.5
Polyglyceryl-2 distearate 0.8
Sorbitan stearate 0.3
PEG-60 hydrogenated castor oil 1.0
Polyglyceryl-10 oleate 1.0
Part B Acrylic acid-alkyl methacrylate copolymer 0.1
K hydroxide 0.07
(VP/Eicosene) Copolymer 0.2
Tremoist-SL (Nippon Fine Chemical) 1.0
Purified water 20.0
Sodium hyaluronate 0.1
Panthenol 0.05
Glycyrrhizinate 2K 0.1
Succinoyl atelocollagen 0.01
Part C Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Lysolecithin 0.02
LP70H (Nippon Fine Chemicals) 0.05
Polysorbate 20 0.4
Glycerin 9.0
1,2-Hexanediol 3.0
1,2-pentanediol 1.5
Sorbitol 2.0
Multitose 2.0
Glyceryl caprylate 0.8
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to a viscous liquid. While stirring part C with a homomixer, part A was added and emulsified. Upon cooling to about 50°C, add Part B, stir and cool to about 40°C.

Example 33 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Mineral oil 5.0
Vaseline 2.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
behenyl alcohol 2.0
Cetearyl alcohol 5.0
Phosphatidylinositol (Soybrain PI50) 0.08
Hydrogenated lecithin (PC content 97%) 0.18
Lecithin (PC content 92%) 0.02
Beeswax 0.7
Polyglyceryl-10 stearate 0.7
Polyglyceryl-10 oleate 0.3
Glyceryl stearate (SE) 1.0
Disteardimonium hectorite 40% liquid 0.2
Part B Phenoxyethanol Appropriate amount Glycerin 3.0
BG 5.0
Citric acid 0.01
Na citrate 0.09
EDTA-2Na 0.05
Purified water 100 in total Part C Xanthan gum 0.16
Dimethicone 50cs 0.5
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were mixed, heated to about 70° C., and uniformly dissolved and dispersed. While stirring part A with a homomixer, part B was added and emulsified. Upon cooling to about 50°C, add Part C, stir and cool to about 40°C.

Example 34 Cleansing Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Plandool-LG2 (Nippon Fine Chemicals) 1.0
LUSPLAN SR-DP4 (Nippon Fine Chemical) 0.2
Neosolue-MP (Nippon Fine Chemicals) 0.2
Diethylhexyl adipate (Nippon Fine Chemicals) 0.5
Diisobutyl adipate (Nippon Fine Chemicals) 0.5
Diethylhexyl succinate (Nippon Fine Chemicals) 1.0
PEG-12 Isostearate 3.0
Sorbeth-30 tetraisostearate 1.5
Polyoxyethylene sorbitan oleate 0.3
Polyglyceryl-10 Laurate 0.3
Microcrystalline wax 2.0
PPG-9 diglyceryl 1.0
Seresin 3.0
Tocopherol 0.05
Part B Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (PC content 97%) 0.1
Lecithin (PC content 92%) 0.01
Polyglyceryl-6 laurate 1.0
Glycolipid (Ceramela-HG) 0.3
Glycerin 9.0
Diglycerin 3.0
1,2-Pentanediol 3.0
Neosolue-Aqua (Nippon Fine Chemicals) 0.5
Neosolue-Aqulio (Nippon Fine Chemicals) 0.5
DPG 5.0
Edetate 3Na 0.02
Phenoxyethanol 0.5
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was dissolved by heating to about 80°C. Part B was warmed to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C.

Example 35 Cleansing foam
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A K stearate 10.0
Potassium palmitate 10.0
Potassium myristate 10.0
Potassium Laurate 4.0
Lauroyl sarcosine isopropyl 0.8
Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Plandool-G (Nippon Fine Chemicals) 0.05
PEG-150 10.0
Glycerin 5.0
1,2-Pentanediol 10.0
Polyglyceryl-10 laurate 0.2
Glyceryl monostearate 1.0
PEG-40 hydrogenated castor oil 0.5
Part B Tremoist-SL (Nippon Fine Chemical) 1.0
Inulin-SC (Nippon Fine Chemicals) 0.3
Polyquaternium-7 0.5
Polyquaternium-39 0.5
Methylparaben 0.1
Purified water Amount to make a total of 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was dissolved by heating to about 80°C. Part B was warmed to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C.

Example 36 Cleansing foam
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
(coconut fatty acid/hydrogenated beef tallow fatty acid) sodium glutamate 20.0
Cocoyl methyl taurine Na 5.0
Cocamidopropyl Betaine 5.0
Lauryl Glucoside 2.0
PEG-9 glyceryl laurate 2.0
Glyceryl Caprylate 1.0
Glycolipid (Ceramela-HG) 0.2
Plandool-LG2 (Nippon Fine Chemicals) 0.2
Lauric acid diethanolamide 3.0
Tocopherol 0.1
PEG-8 5.0
1,2-Pentanediol 10.0
Glycerin 14.0
Part B Hexanediol 1.0
Polyquaternium-51 1.0
Tremoist-SL (Nippon Fine Chemical) 1.0
Inulin-SC (Nippon Fine Chemicals) 0.3
Microcrystalline cellulose 0.3
Polyquaternium-7 0.8
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was dissolved by heating to about 80°C. Part B was warmed to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C.

Example 37 Body Shampoo
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Cocoyl methyl taurine Na 10.0
Lauroyl Hydrolyzed Silk Na 6.0
Lauroyl methylalanine Na 10.0
Sodium cocoamphoacetate (30%) 4.0
Cocamidopropyl betaine (30%) 10.0
Olefin (C14-16) sulfonate Na 5.0
Sucrose Laurate 0.5
Polyquaternium-10 1.3
Hydroxypropyl methylcellulose 0.3
Sodium Acetyl Hyaluronate 0.02
Cocamide DEA 3.0
1,2-Pentanediol 5.0
Glycerin 5.0
BG 3.0
Methylparaben 0.2
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
All the ingredients were heated to about 80° C. and uniformly stirred and mixed.

Example 38 Non-Silicone Shampoo
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Plandool-LG2 (Nippon Fine Chemicals) 0.03
Diethylhexyl succinate (Nippon Fine Chemicals) 0.01
Neosolue-AquaS (Nippon Fine Chemicals) 0.1
Tremoist-SL (Nippon Fine Chemical) 0.5
Sodium laureth-4 carboxylate (28%) 10.0
Laureth-6 carboxylic acid 4.0
Cocamidopropyl betaine (30%) 10.0
Lauroylmethylalanine Na (30%) 5.0
Cocamidomethyl MEA 3.0
Coconut Fatty Acid PEG-7 Glyceryl 5.0
Na hydroxide 1% liquid 0.5
Polyquaternium-10 0.8
Glycol distearate 0.5
Polysorbate 20 0.2
Phytopresome MEL (Nippon Fine Chemicals) 0.8
Polyquaternium-7 0.5
EDTA-2Na 0.05
Glycerin 8.0
1,2-Pentanediol 5.0
Phenoxyethanol 0.4
Sodium benzoate 0.2
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
All the ingredients were heated to about 80° C. and uniformly stirred and mixed.

Example 39 Leave-in hair treatment
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Polyquaternium-37 2.0
Squalane 2.0
PPG-3 caprylyl ether 2.0
Microcrystalline wax 0.1
Lanolin alcohol 0.2
sunflower seed wax 0.1
Polyethylene wax 0.1
Mokurou 0.2
Seresin 0.1
PG Dicaprate 1.0
almond oil 0.5
Ethylhexyl Ethylhexanoate 1.0
Candelilla wax extract 0.1
Octyldodecyl erucate 4.5
Neosolue-DE (Nippon Fine Chemicals) 0.2
Tocopherol Acetate 0.02
Erucalactone MCT (Nippon Fine Chemicals) 2.0
Dipentaerythrityl Tripolyhydroxystearate 1.5
PPG-5 Phytosteryl 0.5
Polyglyceryl-10 laurate 0.2
1,2-Pentanediol 5.0
Glycerin 4.0
DPG 3.0
Sorbitol 2.0
Phenoxyethanol 0.5
Part B Hydrolyzed hyaluronic acid 0.1
Panthenol 0.1
Hydroxypropyltrimonium Hyaluronate 0.01
Polyquaternium-11 0.2
Glycosyltrehalose 0.1
Glyceryl glucoside 0.3
Arginine 0.1
Part C Purified water Amount for a total of 100 Hydroxypropyl starch phosphate 1.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part C was evenly dispersed and warmed to about 80°C. Next, part A was heated to about 80° C. and dissolved. Part A was added to part C while stirring, and after mixing uniformly, the mixture was cooled to about 40°C. Part B was then added respectively and mixed uniformly.

Example 40 Non-Silicone Hair Treatment
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Plandool-LG2 (Nippon Fine Chemicals) 0.5
Propanediol 3.0
behenamidopropyl dimethylamine 1.5
Cetanol 2.2
Stearyl alcohol 0.8
Hydrogenated rapeseed oil alcohol 0.5
Neopentyl glycol diethylhexanoate 0.8
Jojoba seed oil 1.0
Isododecane 1.0
Glyceryl stearate 0.4
Propylparaben 0.1
Cocamidomethyl MEA 0.8
Caesalpinia spinosa hydroxypropyltrimonium chloride 0.1
Rice bran wax 0.5
Erucalactone DES (Nippon Fine Chemicals) 2.0
Part B Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Glycolipid (Ceramela-HG) 0.02
PEG-60 hydrogenated castor oil 0.5
1,2-Pentanediol 3.0
Glycerin 4.0
Purified water 20.0
Part C Phenoxyethanol 0.4
Tremoist-SL (Nippon Fine Chemical) 1.0
Lactic acid 0.4
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were each uniformly mixed at about 80°C. Part B was uniformly dispersed at about 70°C. Part C was gradually added to part A with stirring, mixed uniformly, and then cooled to about 50°C. Part B was added and mixed uniformly.

Example 41 Shampoo for Dandruff
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
PPG-3 caprylyl ether 0.2
Lauroyl methylalanine Na (30%) 13.0
Cocamidopropyl betaine (30%) 20.0
Cocoyl glutamic acid TEA (30%) 5.0
Cocamide DEA 1.0
Polysorbate 80 0.3
1,2-Pentanediol 3.0
Glycerin 1.0
BG 2.0
Glyceryl Caprylate 0.4
Glyceryl undecylenate 0.1
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Sorbitol 1.6
Miconazole nitrate 0.75
Glycol Distearate 1.5
Polyquaternium-7 0.3
Part B Sodium Benzoate 0.4
Na chloride 0.2
Purified water 100 in total Part C Assembly extract 3.0
Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Polyquaternium-47 0.1
Piroctone Olamine 0.1
Purified water 9.7
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part B was heated to about 80° C. and dissolved uniformly. Part A was placed in a separate container and heated to dissolve. Gradually add part B to part A, mix evenly and add part C at about 60°C.

Example 42 Shampoo
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Neosolue-DiSM (Nippon Fine Chemicals) 0.3
Cocoyl sarcosine Na 10.0
Sodium cocoyl glutamate (30%) 10.0
Lauryl hydroxysultaine (30%) 10.0
Glycol distearate 0.5
Polysorbate 20 0.4
Stealoxypropyldimethylamine 0.5
Neosolue-AquaS (Nippon Fine Chemicals) 0.5
Isostearic acid 0.3
Glyceryl undecylenate 0.5
Glycerin 5.0
BG 0.1
Cocamidomethyl MEA 3.0
Phenoxyethanol 0.6
Part B Citric acid 0.1
Methylparaben 0.2
EDTA-2Na 0.1
Purified water 100 in total Part C Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Tremoist-SL (Nippon Fine Chemical) 3.0
Purified water 6.7
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was uniformly mixed at about 80°C. Part B, which was set aside separately, was heated to about 60°C and homogenized. Part B was gradually added to part A with stirring, mixed uniformly, and then cooled to about 50°C. Further, part C was added and mixed uniformly.

Example 43 Leave-on hair treatment
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Phytopresome MEL (Nippon Fine Chemicals) 1.5
Polysorbate 80 0.1
Neosolue-Aqulio (Nippon Fine Chemicals) 2.0
Cetrimonium chloride (25%) 3.8
Isostearic acid 0.02
Erucalactone DES (Nippon Fine Chemicals) 1.0
Caprylyl glucoside (50%) 0.8
Glycerin 4.0
1,2-hexanediol 2.0
Phenoxyethanol 0.5
Part B Ethanol 5.0
Part C Hydrolyzed Keratin 0.2
Hydrolyzed silk 0.1
Hydrolyzed Conchiolin 0.1
Polyquaternium-6 0.6
Polyquaternium-7 0.4
Polyquaternium-39 0.5
Purified water Amount that makes a total of 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part C was warmed to about 80° C. and dissolved. Next, part A was heated to about 80° C. and dissolved. Part A was added to part C while stirring, and after mixing uniformly, the mixture was cooled to about 40°C. Part B was then added and mixed evenly.

Example 44 Treatment Hair Mist
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Phytopresome MEL (Nippon Fine Chemicals) 2.0
Polyglyceryl-10 Laurate 0.5
1,2-Pentanediol 2.0
Glycerin 5.0
PG 3.0
Neosolue-DiSM (Nippon Fine Chemicals) 0.2
Trimethylolpropane triethylhexanoate (Nippon Seika) 0.1
Steartrimonium chloride 0.2
Part B Purified water 40.0
Part C NanoRepair-CMC 10.0
Tremoist-SL (Nippon Fine Chemical) 1.0
Arginine 0.5
Glutamic acid 0.1
Phenylalanine 0.05
Cysteine 0.2
Glycine 0.3
Hydroxyethyl cellulose 0.05
Phenoxyethanol 0.4
Ethanol 5.0
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, they were dispersed using a high-pressure emulsifier (Microfluidizer manufactured by Mizuho Kogyo Co., Ltd.). After cooling, the pre-mixed Part C was added to obtain a uniform liquid.

Example 45 Sunscreen cosmetics
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Phytocompo-PP (Nippon Fine Chemicals) 1.0
LP70H (Nippon Fine Chemicals) 0.2
Sucrose Laurate 1.2
1,2-Pentanediol 9.0
BG 10.0
Glycerin 9.0
Part B Octocrylene 4.0
Octyl Salicylate 4.0
Diethylaminohydroxybenzoyl hexyl benzoate 2.25
t-butyl methoxydibenzoylmethane 1.0
Diethylhexyl sebacate (Nippon Fine Chemicals) 2.0
Diisobutyl adipate (Nippon Fine Chemicals) 2.0
behenyl alcohol 2.0
Cetearyl alcohol 2.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
Plandool-LG1 (Nippon Fine Chemicals) 0.5
Plandool-LG4 (Nippon Fine Chemicals) 0.5
Plandool-S (Nippon Fine Chemicals) 0.5
Tocopherol 0.05
Part C Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Methylparaben Appropriate amount Water Total amount to be 100 Part D Carbomer (2%) 5.0
Tremoist-SL (Nippon Fine Chemical) 10.0
Water-dispersed titanium oxide 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Disperse part A evenly. Part B and part C are heated to about 70° C. and melted. After gradually adding part B to part A, gradually add part C and emulsify. Cool while stirring, add part D at 45°C and stir.

Example 46 Foundation
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Mineral oil 4.0
Vaseline 1.0
Phenyltrimethicone 2.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
(butyl acrylate/glycol dimethacrylate) crosspolymer, silica,
(methyl methacrylate/glycol dimethacrylate) crosspolymer mixture 2.0
Boron Nitride 1.0
Talc 5.0
Zinc oxide 5.0
Titanium oxide 10.0
iron oxide 2.0
Part B Phosphatidylinositol (Soybrain PI50) 0.05
Hydrogenated lecithin (97% PC content) 0.1
Lecithin (PC content 92%) 0.01
Polysorbate 20 0.3
Sucrose myristate 0.8
PEG-20 hydrogenated castor oil 0.5
BG 6.0
Glycerin 8.0
DPG 4.0
Cyclopentasiloxane 9.0
Ethylhexyl methoxycinnamate 3.0
Sorbitan Isostearate 1.5
Tribehenin 0.5
PEG/PPG-19/19 dimethicone, cyclopentasiloxane mixture 4.0
Disteardimonium hectorite (40%) 2.5
Polypropylsilsesquioxane, cyclopentasiloxane mixture 1.0
Part C Tremoist-SL (Nippon Fine Chemicals) 10.0
Maltitol (75%) 1.0
Neosolue-AquaS (Nippon Fine Chemicals) 0.4
Na chloride 1.0
Methylparaben Appropriate amount Tocopherol Appropriate amount Water Total 100－－－－－－－－－－－－－－－－－－－－－－－ ---
(Preparation method)
Part A was heated to about 70° C. and thoroughly stirred to uniformly disperse. Part B is heated to 70° C. and homogenized, then part B is gradually added to part A, then part C is gradually added and emulsified.

Example 47 Foundation
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phosphatidylinositol (Soybrain PI50) 0.04
Hydrogenated lecithin (PC content 97%) 0.09
Lecithin (PC content 92%) 0.01
Glycerin 10.0
1,2-Pentanediol 5.0
Plandool-G (Nippon Fine Chemicals) 5.0
POE(20) Phytosterol 1.0
Polyglyceryl-10 oleate 0.2
Glyceryl stearate (SE) 0.5
PG stearate (SE) 0.5
Tocopherol 0.1
Propylparaben 1.0
Part B Titanium oxide/iron oxide mixture (FDP-W-007 manufactured by Toshiki Pigment Co., Ltd.) 18.0
Mica 7.0
BG 5.0
Methylparaben 0.2
Purified water 100 in total Part C Cellulose gum (2% aqueous dispersion) 5.0
Xanthan gum (2% aqueous dispersion) 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B and part C were heated and mixed. After adding part B to part A and emulsifying the mixture, the mixture was cooled to about 50°C, added with part C, and stirred until uniform.

In the above formulation, the details of the ingredients described in the product names are as follows.

〇 LUSPLAN DD-IS: dimer dilinoleyl diisostearate 〇 LUSPLAN PI-DA: di(isostearyl/phytosteryl) dimer dilinoleate
〇 LUSPLAN DD-DHR: dimer dilinoleyl hydrogenated rosin condensate 〇 LUSPLAN DD-DA5: dimer dilinoleyl dimer dilinoleate 〇 LUSPLAN DD-DA7: dimer dilinoleyl dimer dilinoleate 〇 LUSPLAN SR-DM4: dye Dimer dilinoleyl dilinoleate, tri(caprylic/capric)glyceryl 〇 LUSPLAN SR-DP4: Dimer dilinoleyl dimer dilinoleate, pentaerythrityl tetraisostearate 〇 Inulin-SC: Inulin 〇 NanoRepair-CMC: Quaternium -18, quaternium-33, cholesterol, ceramide 2, ceramide 3, ceramide 6II, PG-containing composition 〇Neosolue-Aqulio: bisethoxydiglycol cyclohexanedicarboxylate 〇Neosolue-Aqua: (eicosanedioic acid/tetradecanedioic acid) polyglyceryl- 10, glycerin 〇 Neosolue-AquaS: (eicosanedioic acid / tetradecanedioic acid) polyglyceryl-10, glycerin 〇 Neosolue-DiSM: diisostearyl malate 〇 Neosolue-MP: methyl pentanediol dineopentanoate 〇 Neosolue-DE: diethyl dineopentanoate Pentanediol ○ Plandool-H: dimer dilinoleic acid (phytosteryl/isostearyl/cetyl/stearyl/behenyl)
〇Plandool-S: dimer dilinoleic acid (phytosteryl/isostearyl/cetyl/stearyl/behenyl)
〇 Plandool-G: dimer dilinoleyl bis(behenyl/isostearyl/phytosteryl) dimer dilinoleate
○ Plandool-DP: Bis-diglyceryl polyacyl adipate-2
〇 Plandool-ISS: Phytosteryl isostearate 〇 Plandool-SUN: Sunflower seed oil fatty acid phytosteryl 〇 Plandool-MAS: Macadamia nut oil fatty acid phytosteryl 〇 Plandool-LG1: Lauroyl glutamate di(phytosteryl/octyldodecyl/behenyl)
○ Plandool-LG2: Lauroyl glutamate di(phytosteryl/octyldodecyl)
○ Plandool-LG3: Lauroyl glutamate di(phytosteryl/octyldodecyl/behenyl)
○ Plandool-LG4: Lauroyl glutamate di(phytosteryl/octyldodecyl/behenyl)
○ Phytocompo-PP: hydrogenated lecithin, phytosterols ○ Phytocompo-C: hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3, ceramide 6II
〇 Phytopresome Asta: hydrogenated lecithin, phytosterols, astaxanthin 〇 Phytopresome Lipo-Q: hydrogenated lecithin, phytosterols, lipoic acid, coenzyme Q10
○ Phytopresome Cera23: hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3
〇 Phytopresome MEL: Glycolipid, hydrogenated lecithin, BG, purified water 〇 Tremoist-TP: Tremoist-TP: Tremoist-SL: Tremoist-SL: Tremoist-SL: Aqueous solution of tremella fungus (1%)
〇LP70H: Hydrogenated Lysolecithin 〇Ercalactone MCT: γ-docosalactone, tri (caprylic/capric)glyceryl 〇Ercalactone DES: γ-docosalactone, diethyl sebacate

Claims (7)

A cosmetic or topical skin preparation comprising the following components (A) to (D) , wherein the weight ratio of components (A1) and (A2) is 5:95 to 50:50.
(A) A phospholipid composition comprising the following components (A1) and (A2): (A1) phosphatidylinositol (A2) lecithin having a phosphatidylcholine (PC) content of 50 to 99% by weight (B) polyhydric alcohol (C) nonionic surfactant (D) water The content of component (A) is 0.001 to 5% by weight, the weight ratio of components (A) and (B) is 1:5 to 1:200, and the content of components (A) and (C) is 2. The cosmetic or topical preparation for skin according to claim 1, wherein the weight ratio is from 1:0.1 to 1:10. 3. The cosmetic or external preparation for skin according to claim 1, wherein the lecithin of component (A2) is a mixture of hydrogenated lecithin and non-hydrogenated lecithin. Nonionic surfactant of component (C) is glycerin fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester, mannosylerythritol lipid, polyoxyethylene glycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene fatty acid ester. 4. The cosmetic composition according to any one of claims 1 to 3 , which is one or more selected from polyoxyethylene alkyl ether and polyoxyethylene alkyl ether. 5. The cosmetic or external preparation for skin according to any one of claims 1 to 4 , further comprising sterols or triterpenes as component (E). 6. The cosmetic or topical preparation for skin according to any one of claims 1 to 5 , further comprising an antioxidant as component (F). 7. The cosmetic or external preparation for skin according to any one of claims 1 to 6 , which has a transparent appearance.