JP2020002055A - Cosmetics containing novel malate - Google Patents

Abstract

To provide an oil solution which comprises a malic acid skeleton and has excellent lamella forming capability, and cosmetics containing the oil solution.SOLUTION: A malate represented by the general formula (1) in the figure is used. The malate can form a lamella structure by mixture with water, and exhibits excellent moisture retention effect and skin barrier function improving effect. (In the formula, R represents a C14-28 linear aliphatic alcohol residue.)SELECTED DRAWING: None

Description

  The present invention relates to a cosmetic containing a novel malic acid ester having lamellar forming ability.

  The stratum corneum intercellular lipid is mainly composed of ceramide, cholesterol, and fatty acids, and forms a layered structure (lamellar structure) sandwiching water. The formation of such a lamellar structure has an effect on the moisture retention and barrier function of the skin. It is known to play an important role. In cosmetics, it is common to use oils such as hydrocarbon oils and ester oils for the purpose of moisturizing and imparting flexibility to the skin, and oils having water retentivity are preferred because they further enhance the moisturizing effect. used. On the other hand, if it is an oil that forms a lamellar structure like intercellular lipids, it has a different effect from the above oil, and it is expected to have a better moisturizing effect, and furthermore an effect of improving the barrier function of the stratum corneum, Attempts have been made to use oils that form such a lamellar structure in cosmetics (for example, Patent Documents 1 and 2).

  Malic acid is a kind of organic acid found in apple, and is a component widely used in cosmetics because of its excellent safety and stability. For this reason, malic acid derivatives are also used in cosmetics applications, and as a malic acid ester derivative, diisostearyl malate (multi-branched 5,7,7-trimethyl-2- (1 as isostearyl alcohol) is used. , 3,3-trimethylbutyl) -octan-1-ol), dialkyl malate (C12,13), and diethylhexyl malate are known (Patent Documents 3 and 4). However, these esters did not always have a sufficient moisturizing effect as an oil agent.

JP-A-9-132512 JP 2013-49633 A JP-A-62-051610 JP-A-2004-091407

  An object of the present invention is to provide an oil having a malic acid skeleton and excellent lamellar forming ability, and a cosmetic containing the oil.

Means for Solving the Problems As a result of intensive studies to solve the above problems, the present inventors have found that a malate ester represented by the following general formula (1) solves the above problems, and have completed the present invention.
(In the formula, R represents a linear aliphatic alcohol residue having 14 to 28 carbon atoms.)

  The malate ester of the present invention can form a lamellar structure by being mixed with water, and exhibits excellent moisturizing and skin barrier function improving effects.

The present invention is a cosmetic containing a malate ester represented by the following general formula (1).
(In the formula, R represents a linear aliphatic alcohol residue having 14 to 28 carbon atoms.)

  Specific examples of the malic acid used for producing the malic ester of the present invention include L-malic acid, D-malic acid, and DL-malic acid. In the present invention, any of these can be used. These may be used alone or in combination of two or more. Among them, DL-malic acid can be preferably used from the viewpoint of economy.

  Specific examples of the linear aliphatic alcohol having 14 to 28 carbon atoms used for producing the malate ester of the present invention include tetradecanol, pentadecanol, hexadecanol, heptadecanol and octadecanol. , Nonadecanol, eicosanol, heneicosanol, docosanol, tricosanol, tetracosanol, hexacosanol and octacosanol. These may be used alone or in combination of two or more. Among these, from the viewpoint of exhibiting excellent lamellar-forming ability, straight-chain aliphatic alcohols having 16 to 22 carbon atoms are preferred, and specifically, hexadecanol, heptadecanol, octadecanol, nonadecanol, eicosanol, heneico Sanol and docosanol are preferred.

  Although the method for producing the malate ester of the present invention is not necessarily limited, it can be produced by the following method. That is, esterification of the raw material malic acid and the linear aliphatic alcohol at a molar ratio of 1: 1.5 to 1: 2.5, more preferably at a ratio of 1: 1.8 to 1: 2.2. Is obtained by The conditions for the esterification reaction are not particularly limited, and the esterification reaction is performed by a commonly used method. For example, when a catalyst is used, paratoluenesulfonic acid, sulfuric acid, phosphoric acid, hydrochloric acid, methanesulfonic acid, boron trifluoride diethyl ether complex, titanium alcoholate, a solid acid catalyst, and the like are used as a solvent, and heptane, hexane, cyclohexane, and toluene are used as solvents. , Xylene or the like at 50 to 260 ° C. Alternatively, the esterification can be performed at 100 to 260 ° C. without a solvent or a catalyst. Further, the obtained ester may be purified and used by an ordinary method as necessary. For example, residual free carboxylic acid may be removed by washing with an alkaline aqueous solution, or purification such as distillation, steam deodorization, and activated carbon treatment may be performed for the purpose of reducing odor and improving stability. The malic acid ester of the present invention thus obtained may contain a monoester, an unreacted aliphatic alcohol, or an esterified product of a dimer of malic acid, in addition to the diester.

  The malic acid ester of the present invention thus obtained can form a lamellar structure by mixing with water, has an excellent moisturizing effect and an effect of improving skin barrier function, and is preferably used in cosmetics. Can be used.

  The amount of the malate ester of the present invention to be added to cosmetics is not particularly limited as long as the effects of the present invention are not impaired, and is usually 0.01 to 40% by weight, preferably 0.05 to 20% by weight. %.

  The cosmetic of the present invention may contain water and optional components usually incorporated into cosmetics, such as an oily base, a surfactant, an alcohol, a humectant, a polymer, a thickener, a gelling agent, and an oxidizer. Inhibitors, preservatives, bactericides, chelating agents, pH adjusters / acids / alkali, UV absorbers, whitening agents, solvents, exfoliants / dissolvents, antipruritics, anti-inflammatory agents, antiperspirants, fresheners, antihistamines, Astringents, stimulants, hair growth agents / blood circulation promoters, reducing agents / oxidants, polymer powders, hydroxy acids, vitamins and their derivatives, sugars and their derivatives, organic acids, enzymes, nucleic acids, Hormones, inorganic powders, fragrances, pigments and the like may be contained to such an extent that the effects of the present invention are not impaired.

  Oil bases include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol, jojoba alcohol, kimyl alcohol, seraky alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, Higher alcohols such as 2-octyldodecanol and dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, Palmitooleic acid, oleic acid, linoleic acid, linoleic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexa Higher fatty acids such as canic acid, anteisohenicosanoic acid, long-chain branched fatty acids, dimer acids and hydrogenated dimer acids and metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium, sodium salts thereof. And nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, petrolatum, solid Hydrocarbons such as paraffin; candelilla wax, carnauba wax, rice wax, wood wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, fisher Waxes such as tropsch wax, polyethylene wax, ethylene-propylene copolymer; coconut oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut Oil, hazelnut oil, kukuinut oil, rosehip oil, meadowfoam oil, persic oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, flaxseed oil, cottonseed oil, soybean oil, peanut oil, rice bran Vegetable oils such as oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil; animal properties such as beef tallow, milk fat, horse fat, egg yolk oil, mink oil and turtle oil Oils and fats; animal waxes such as whale wax, lanolin, orange luffy oil; liquid lanolin, reduced lanolin Lanolins such as adsorbed and purified lanolin, lanolin acetate, lanolin acetate liquid, hydroxylanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin alcohol acetate, acetic acid (cetyl lanolyl) ester; lecithin, phosphatidylcholine, Phospholipids such as phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingomyelin, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof, and phospholipids such as lysolecithin; hydrogenated soybean phospholipids, partially hydrogenated soybean phosphorus Phospholipid derivatives such as lipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids; sapogenins; saponins; cholesteryl acetate, nonanoic acid Resteryl, cholesteryl stearate, cholesteryl isostearate, cholesteryl oleate, di-N-lauroyl-L-glutamate (cholesteryl / behenyl / octyldodecyl), di-N-lauroyl-L-glutamate (cholesteryl / octyldodecyl), N-lauroyl- L-glutamic acid di (phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamic acid di (phytosteryl / octyldodecyl), acyl sarcosine alkyl ester such as N-lauroyl sarcosine isopropyl, cholesteryl 12-hydroxystearate, macadamia nut oil fatty acid Cholesteryl, macadamia nut oil fatty acid phytosteryl, sunflower seed oil fatty acid phytosteryl, phytosteryl isostearate, soft lano Sterol esters such as cholesteryl phosphate fatty acid, cholesteryl hard lanolin fatty acid, cholesteryl long chain fatty acid, and cholesteryl long chain α-hydroxy fatty acid; lipid complexes such as phospholipid / cholesterol complex, phospholipid / phytosterol complex; octyl myristate Dodecyl, hexyldecyl myristate, octyldodecyl isostearate, cetyl palmitate, octyldodecyl palmitate, cetyl octanoate, hexyldecyl octanoate, isotridecyl isononanoate, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanate, Isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, oleyl oleate, octyl oleate Dodecyl, octyldodecyl ricinoleate, octyldodecyl lanolin fatty acid, dicaprylyl carbonate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, hydrogenated castor oil isostearate, ethyl oleate, avocado oil fatty acid ethyl, isopropyl myristate, isopropyl palmitate, palmitin Octyl acid, isopropyl isostearate, isopropyl lanolin fatty acid, methyl heptyl laurate, methyl heptyl myristate, methyl heptyl palmitate, methyl heptyl isostearate, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyl sebacate Octyl, diisobutyl adipate, dioctyl adipate, dioctyl succinate, citric acid Monoalcohol carboxylic esters such as triethyl; oxyesters such as cetyl lactate, diisostearyl malate, hydrogenated castor oil monoisostearate, and γ-elcalactone; glyceryl trioctanoate, glyceryl trioleate, and triisostearic acid Glyceryl, glyceryl diisostearate, glyceryl tri (caprylic / capric acid), tri (caprylic / capric / myristic / stearic) glyceryl, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), Glyceryl eicosane diacid behenate, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, neopentyl glycol dioctanoate, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol octanoate, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenated rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate, (isostearic acid / sebacic acid) Ditrimethylolpropane, pentaerythrityl triethylhexanoate, (hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl, diglyceryl diisostearate, polyglyceryl tetraisostearate, polyglyceryl-10 nonisostearate, deca (erucic acid / isostearic acid / ricinolein) Acid) polyglyceryl-8, (hexyldecanoic acid / sebacic acid) diglyceryl oligoester, glycol distearate (ethylene distearate) Polyglycol fatty acid esters such as lenglycol), 3-methyl-1,5-pentanediol dineopentanoate and 2,4-diethyl-1,5-pentanediol dineopentanoate; alkyl ethers such as dicaprylyl ether; Diisopropyl dimer dilinoleate, diisostearyl dimer dilinoleate, di (isostearyl / phytosteryl) dimer dilinoleate (phytosteryl / behenyl), dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl) ), Dimer dilinoleyl dimer dilinoleate, dimer dilinoleyl diisostearate, hydrogenated rosin condensate of dimer dilinoleyl, dimer dilinoleic acid-hardened castor oil, hydroxyalkyl dimer relinole Derivatives of dimer acids or dimer diols such as diethers; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA) Fatty acid alkanolamides such as lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA), palmitic acid diethanolamide (partamide DEA), coconut oil fatty acid methylethanolamide (cocamide methyl MEA); dimethicone (dimethyl) Polysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclope) Siloxane), phenyltrimethicone, diphenyldimethicone, phenyldimethicone, (aminoethylaminopropylmethicone / dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified dimethicone, amodimethicone and other amino-modified silicones, cations Modified silicone, polyether-modified silicone such as dimethicone copolyol, polyglycerin-modified silicone, sugar-modified silicone, carboxylic acid-modified silicone, phosphoric acid-modified silicone, sulfuric acid-modified silicone, alkyl-modified silicone, fatty acid-modified silicone, alkyl ether-modified silicone, amino acid Modified silicone, peptide-modified silicone, fluorine-modified silicone, cation-modified and polyether-modified silicone Silicones such as corn, amino-modified and polyether-modified silicone, alkyl-modified and polyether-modified silicone, amide alkyl-modified silicone, aminoglycol-modified silicone, aminophenyl-modified silicone, and polysiloxane / oxyalkylene copolymer; perfluorodecane; Fluorinated oils such as perfluorooctane and perfluoropolyether are preferred.

  Examples of humectants / feel improvers include glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Polyethylenes such as trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol / propylene glycol copolymers, and polymers thereof; diethylene glycol monoethyl ether (Ethoxydiglycol), glycol alkyl ethers such as ethylene glycol monoethyl ether, ethylene glycol monobutyl ether and diethylene glycol dibutyl ether Water-soluble esters such as (eicosane diacid / tetradecandioic acid) polyglyceryl-10, polyglyceryl-10 tetradecandioate and bisethoxydiglycol cyclohexanedicarboxylate; sugars such as sorbitol, xylitol, erythritol, mannitol and maltitol Alcohols: glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ- Cyclodextrins and modified cyclodextrins such as maltosylation and hydroxyalkylation), β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabino Saccharides such as galactan, dextrin, dextran, glycogen, ethyl glucoside, glucosylethyl methacrylate polymer or copolymer and derivatives thereof; hyaluronic acid, sodium hyaluronate; chondroitin sulfate sodium; mucoitin sulfate, caronine sulfate, kerato sulfate, dermatan Sulfuric acid; white jellyfish extract, white jellyfish polysaccharide; fructans such as inulin and levan; fucoidan; tuberose polysaccharide, a naturally occurring polysaccharide; organic acids such as citric acid, tartaric acid and lactic acid and salts thereof; urea; 2-pyrrolidone-5 -Carboxylic acids and salts thereof such as sodium; betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine Amino acids such as glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine and salts thereof; collagen, fish-derived collagen, atelocollagen, gelatin, elastin, collagen-degrading peptide, Hydrolyzed Collagen, Hydroxypropylammonium Chloride Hydrolyzed Collagen, Elastin Degraded Peptide, Keratin Degraded Peptide, Hydrolyzed Keratin, Conchiolin Degraded Peptide, Hydrolyzed Conchiolin, Silk Proteolytic Peptide, Hydrolyzed Silk, Lauroyl Hydrolyzed Silk Sodium, Soybean Proteolysis Protein peptides such as peptides, wheat proteolytic peptides, hydrolyzed wheat proteins, casein degrading peptides, acylated peptides and the like Derivatives; acylated peptides such as palmitoyl oligopeptide, palmitoyl pentapeptide, and palmitoyl tetrapeptide; silylated peptides; lactic acid bacteria culture, yeast extract, eggshell membrane protein, bovine submandibular mucin, hypotaurine, sesame lignan glycoside, Glutathione, albumin, whey; choline chloride, phosphorylcholine; placenta extract, aerastin, collagen, aloe extract, hamamelis water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, Izayobara extract, Achillea millefolium extract, Animal / plant extract components such as eucalyptus extract, melilot extract, natural ceramide (types 1, 2, 3, 4, 5, 6), hydroxyceramide, pseudo-ceramide, glycosphingolipid, ceramide and sugar-ceramide-containing extract, etc. Ceramides can be mentioned as preferred.

Preferred examples of the surfactant include an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, and a polymer surfactant. There is no particular limitation on the HLB of the surfactant, and it can be used from as low as about 1 to as high as about 20. It is also preferable to combine low and high HLB. Preferred examples of the surfactant include anionic surfactants such as fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate salts such as sodium lauryl sulfate, triethanolamine lauryl sulfate and ammonium lauryl sulfate; laureth Polyoxyethylene alkyl sulfates such as sodium sulfate and triethanolamine laureth sulfate; cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, myristoyl methyl taurine sodium, lauroyl methyl alanine sodium, lauroyl sarcosine sodium, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amines and sodium lauroylglutamate methylalanine sodium; Acyl amino acid salts such as sodium silicate, triethanolamine cocoylglutamate, sodium lauroylglutamate, sodium myristoylglutamate, sodium stearoylglutamate, ditriethanolamine palmitoylaspartate, cocoylalanine triethanolamine, lysine sodium dilauroylglutamate; sodium laureth acetate; Polyoxyethylene alkyl ether acetate; succinic acid ester salt such as sodium lauroyl monoethanolamide succinate; fatty acid alkanolamide ether carboxylate; acyl lactate; polyoxyethylene fatty amine sulfate; fatty acid alkanolamide sulfate; Fatty acid glyceride sulfates such as coconut oil fatty acid sodium glycerin sulfate; Oxyethylene sulfates; olefin sulfonates such as sodium α-olefin sulfonate; alkylsulfosuccinates such as disodium lauryl sulfosuccinate and dioctyl sodium sulfosuccinate; disodium laureth sulfosuccinate; monolauroyl monoethanolamide polyoxyethylene sulfosuccinate Alkyl ether sulfosuccinates such as sodium silicate, lauryl polypropylene glycol sodium sulfosuccinate; alkylbenzene sulfonates such as sodium tetradecylbenzenesulfonate and triethanolamine tetradecylbenzenesulfonate; alkyl naphthalene sulfonates; alkane sulfonates; α-sulfofatty acid methyl ester salt; acyl isethionate salt; alkyl glycidyl ether sulfonate Alkyl sulfoacetates; Alkyl ether phosphates such as sodium laureth phosphate, sodium dilaurate phosphate, sodium trilaureth phosphate, sodium monooleate phosphate; Alkyl phosphates such as potassium lauryl phosphate; Sodium caseinate; Alkyl aryl ether phosphorus Acid salts; fatty acid amide ether phosphates; phospholipids such as phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof; silicone-based shades such as carboxylic acid-modified silicone, phosphoric acid-modified silicone, and sulfuric acid-modified silicone Ionic surfactants and the like; examples of nonionic surfactants include laureth (polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), and stearee. (Polyoxyethylene stearyl ether), behenes (polyoxyethylene behenyl ether), isosteareth (polyoxyethylene isostearyl ether), octyl dodeces (polyoxyethylene octyl dodecyl ether) Polyoxyethylene alkyl ethers; polyoxyethylene alkyl phenyl ether; polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, Castor oil and hydrogenated castor oil derivatives such as polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, polyoxyethylene hydrogenated castor oil maleic acid; poly Polyoxyethylene cholesterol; polyoxyethylene cholesterol; polyoxyethylene lanolin; polyoxyethylene reduced lanolin; polyoxyethylene / polyoxypropylene cetyl ether; polyoxyethylene / polyoxypropylene 2-decyltetradecyl ether; Polyoxyethylene / polyoxypropylene alkyl ether such as polyoxyethylene / polyoxypropylene monobutyl ether, polyoxyethylene / polyoxypropylene hydrogenated lanolin, polyoxyethylene / polyoxypropylene glycerin ether; polyoxyethylene / polyoxypropylene glycol (Poly) glycerin polyoxypropylene glycol such as PPG-9 diglyceryl; Ryl, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, glyceryl oleate, glyceryl coconut oil, glyceryl mono-cottonseed oil, glyceryl monoerucate, glyceryl sesquioleate, glycerin α, α'-pyroglutamate oleate, monostearin Glycerin fatty acid partial esters such as acid glycerin malate; polyglyceryl-2, 3, 4, 5, 6, 8, 10, disglyceryl-6, 10, and polyglyceryl tristearate 2, polyglyceryl-10 decasterate, polyglyceryl-2 isostearate, 3, 4, 5, 6, 8, 8, 10, diglyceryl-2 diisostearate (diglyceryl diisostearate), 3, 3 , Polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, 3, 4, 5, 5, 6, 8, 10, polyglyceryl dioleate 6, polyglycerin fatty acid esters such as polyglyceryl-2 trioleate and polyglyceryl-10 decaoleate; ethylene glycol monofatty acid esters such as ethylene glycol monostearate; propylene glycol monofatty acid esters such as propylene glycol monostearate; pentaerythritol moiety Fatty acid ester; sorbitol partial fatty acid ester; maltitol partial fatty acid ester; maltitol ether; sorbitan monooleate, sorbitan monoisostearate Sorbitan fatty acid esters such as sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol penta-2-ethylhexylate sorbitan, and diglycerol sorbitan tetra-2-ethylhexylate; Sugar derivative partial esters such as sucrose fatty acid ester, methyl glucoside fatty acid ester and trehalose undecylenate; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; glycolipids such as mannosyl erythritol lipid; lanolin alcohol; reduced lanolin; Stearates, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene dioleate, etc. Polyoxyethylene fatty acid monoesters and diesters; polyoxyethylene propylene glycol fatty acid esters; polyoxyethylene monooleates such as polyoxyethylene glycerin monostearate, polyoxyethylene glycerin monoisostearate, and polyoxyethylene glycerin triisostearate Polyoxyethylene glycerin fatty acid esters such as ethate; polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan tetraoleate; poly Oxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol Polyoxyethylene sorbitol fatty acid esters such as bitol pentaoleate and polyoxyethylene sorbitol monostearate; polyoxyethylene methyl glucoside fatty acid esters; polyoxyethylene alkyl ether fatty acid esters; polyoxyethylene animal and vegetable fats and oils such as polyoxyethylene sorbitol beeswax Alkyl glyceryl ethers such as isostearyl glyceryl ether, chimyl alcohol, serakyl alcohol, and batyl alcohol; polyhydric alcohol alkyl ethers; polyoxyethylene alkylamines; tetrapolyoxyethylene / tetrapolyoxypropylene-ethylenediamine condensates; Natural surfactants such as saponin and sophorolipid; polyoxyethylene fatty acid amide; coconut oil fatty acid monoethano Luamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide Fatty acid alkanolamides such as (partamide MEA), palmitic acid diethanolamide (partamide DEA) and coconut oil fatty acid methylethanolamide (cocamide methyl MEA); alkyls such as lauramine oxide, cocamine oxide, stearamine oxide and behenamine oxide Dimethylamine oxide; alkylethoxydimethylamine oxide; polyoxyethylene alkyl mercaptan; polyethers such as dimethicone copolyol Silicone-based nonionic surfactants such as silicone-modified silicone, polysiloxane / oxyalkylene copolymer, polyglycerin-modified silicone, and sugar-modified silicone; cationic surfactants include behentrimonium chloride and stearyltrimonium chloride Alkyltrimethylammonium chlorides such as cetrimonium chloride and lauryltrimonium chloride; alkyltrimethylammonium bromides such as stearyltrimonium bromide; dialkyldimethylammonium chlorides such as distearyldimonium chloride and dicocodimonium chloride; stearamidopropyldimethylamine; Fatty acid amidoamines such as stearamidoethyldiethylamine and salts thereof; alkyl etheramines such as stearoxypropyldimethylamine and Or quaternary salts of fatty acids; fatty acid amide-type quaternary ammonium salts such as ethyl sulfate long-chain branched fatty acid (12-31) aminopropylethyldimethylammonium and lanolin ethyl sulfate aminopropylethyldimethylammonium; polyoxyethylene alkylamine and the like Salts or quaternary salts; alkylamine salts; fatty acid amide guanidinium salts; alkyl ether amine monium salts; alkyltrialkylene glycol ammonium salts; benzalkonium salts; benzethonium salts; pyridinium salts such as cetylpyridinium chloride; Alkyl isoquinolinium salts; dialkyl morphonium salts; polyamine fatty acid derivatives; amino-modified silicones such as aminopropyl dimethicone and amodimethicone; And silicone-based cationic surfactants such as polyether-modified silicone, amino-modified and polyether-modified silicone; and amphoteric surfactants include N-alkyl-N, N- such as lauryl betaine (lauryl dimethylamino acetate betaine). Dimethylamino acid betaine; fatty acid amide alkyl-N, N-dimethylamino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; alkylsulfobetaines such as alkyldimethyltaurine; alkyl Sulfate betaines such as dimethylaminoethanol sulfate; phosphate betaines such as alkyl dimethylaminoethanol phosphate; phosphatidylcholine, phosphatidylethanolamine , Phosphatidylserine, sphingomyelin and other sphingolipids, lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid, phospholipids such as hydroxylated lecithin; Preferred examples of the polymeric amphoteric surfactant include polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum, acrylic acid / alkyl methacrylate copolymer, and various silicone-based surfactants.

  Guar gum, locust bean gum, queen seeded, carrageenan, galactan, gum arabic, tara gum, tamarind, furceleran, karaya gum, troloi, chara gum, tragacanth gum, pectin, pectic acid and sodium Salts such as salts, salts such as alginic acid and sodium salt, mannan; starches such as rice, corn, potato, wheat, etc .; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salts, xanthan gum, pullulan, gellan gum, chitin , Chitosan, agar, licorice extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropyl Cellulose, carboxymethylcellulose and salts thereof such as sodium, methylhydroxypropylcellulose, cellulose sodium sulfate, dialkyldimethylammonium cellulose cellulose, crystalline cellulose, cellulose such as cellulose powder and derivatives thereof; soluble starch, carboxymethyl starch, methylhydroxypropyl starch; Starch polymers such as methyl starch, starch derivatives such as hydroxypropyltrimonium chloride starch, and corn starch aluminum octenylsuccinate; alginic acid derivatives such as sodium alginate and propylene glycol alginate; polyvinylpyridone (PVP), polyvinyl alcohol (PVA); Vinyl pidolidone / vinyl alcohol copolymer, polyvinyl methylate Amphoteric methacrylic acid such as polyethylene glycol, polypropylene glycol, polyoxyethylene / polyoxypropylene copolymer; (methacryloyloxyethylcarboxybetaine / alkyl methacrylate) copolymer, (acrylates / stearyl acrylate / ethylamine methacrylate) copolymer (Dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, (alkyl acrylate / diacetone acrylamide) copolymer AMP; partially saponified polyvinyl acetate, maleic acid copolymer; Vinylpyrrolidone / dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester; water-dispersible polyester; Acrylamide; polyacrylic acid ester copolymer such as polyethyl acrylate; carboxyvinyl polymer; polyacrylic acid and salts thereof such as sodium salt; acrylic acid / methacrylic acid ester copolymer; acrylic acid / alkyl methacrylate Polymer; cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-7, acrylic acid / diallyldimethylammonium chloride copolymer such as polyquaternium-22, acrylic acid such as polyquaternium-39・ Diallyldimethylammonium chloride / acrylamide copolymer, acrylic acid / cationized methacrylate copolymer, acrylic acid / cationized methacrylamide copolymer, polyquaternium Cationized oligosaccharides, cationized polysaccharides such as cationized dextran, guar hydroxypropyltrimonium chloride, etc .; acrylic acid / methyl acrylate / methacrylamidopropyltrimethylammonium chloride copolymer; Polyethyleneimine; cationic polymer; copolymer of 2-methacryloyloxyethyl phosphorylcholine such as polyquaternium-51 and copolymer with butyl methacrylate; acrylic resin emulsion, polyethyl acrylate emulsion, polyacryl alkyl ester emulsion; Polymer emulsions such as polyvinyl acetate resin emulsion, natural rubber latex, and synthetic latex; nitrocellulose; polyurethanes and various copolymers; Classes; various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluorine-based polymers; 12-hydroxystearic acid and salts thereof; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; silicic anhydride; Fumed silica (ultrafine silica anhydride), aluminum magnesium silicate, sodium magnesium silicate, metal soap, metal dialkyl phosphate, bentonite, hectorite, organically modified clay mineral, sucrose fatty acid ester, fructooligosaccharide fatty acid ester Preferred are mentioned.

  Solvents and propellants include lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol, and isobutyl alcohol; glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, and isopentyl diol. Classes: diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether Glycol ethers such as ethylene glycol monoethyl ether Glycol ether esters such as acetate, diethylene glycol monoethyl ether acetate and propylene glycol monoethyl ether acetate; glycol esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, and dialkyl carbonate , Acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbon, next-generation chlorofluorocarbon; and propellants such as LPG, dimethyl ether, and carbon dioxide.

  As antioxidants, tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or derivatives thereof; erythorbic acid and derivatives thereof; Sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfite; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, and cysteine hydrochloride are preferred As Preferred examples of the reducing agent include thioglycolic acid, cysteine, and cysteamine. Preferred examples of the oxidizing agent include aqueous hydrogen peroxide, ammonium persulfate, sodium bromate, percarbonate and the like.

  Examples of antibacterial agents or preservatives include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben, and butylparaben; phenoxyethanol; 1,2-pentanediol, 1,2-hexanediol, and 1,2-octane. 1,2-alkanediols such as diols; alkylglyceryl ethers such as 2-ethylhexylglyceryl ether (ethylhexylglycerin); salicylic acid; sodium benzoate; isothiazolineone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; imidazo Linium urea; dehydroacetic acid and salts thereof; phenols; halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, ben chloride Ruconium, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, and phenylphenol sodium; phenylethyl alcohol , Photosensitizers, antibacterial zeolites and silver ions are preferred. When used as an antiseptic or antiseptic for antiseptic purposes, phenoxyethanol from the viewpoint of safety of cosmetics or external preparations for skin; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol and 1,2-octanediol; alkyl glyceres such as 2-ethylhexyl glyceryl ether It is more preferred to use ethers.

  Examples of the chelating agent include edetates (ethylenediaminetetraacetate) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetate such as HEDTA3Na; pentetate (diethylenetriaminepentaacetate); phytic acid; etidronic acid and the like Sodium oxalate; polypolyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine , Gluconic acid, ascorbic acid, succinic acid and tartaric acid are preferred. pH adjusters ・ Acids and alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanol Amine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxylated Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferred.

  Examples of powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, biotite, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluoroapatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metallic soaps (e.g., zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, red iron oxide, yellow iron oxide, black iron oxide, ultramarine, navy blue, carbon black, titanium oxide, fine particles and ultrafine Titanium oxide, zinc oxide, fine particles and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silica), mica titanium, fish scale foil, boron nitride, photochromic pigment, synthetic fluorophlogopite, fine particle composite powder Inorganic powders of various sizes and shapes such as body, gold, aluminum, etc., and treated with various surface treatment agents such as hydrogen silicone, silicone such as cyclic hydrogen silicone, or other silane or titanium coupling agents Inorganic powder such as powder that has been hydrophobized or hydrophilized; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, polyester powder, Benzoguanamine resin powder, polyethylene terephthalate / polymethyl Organic powders and surface-treated powders of various sizes and shapes, such as methacrylate laminate powder, polyethylene terephthalate / aluminum / epoxy laminate powder, urethane powder, silicone powder, Teflon (registered trademark) powder, and organic-inorganic composite powder Are preferred. As inorganic salts, sodium chloride-containing salts such as common salt, normal salt, rock salt, sea salt, natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum potassium potassium sulfate (alum), aluminum ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na / 2Na / 3Na phosphate, phosphoric acid Potassiums, calcium phosphates, and magnesium phosphates are preferred.

  Examples of the ultraviolet absorber include paraaminobenzoic acid, paraaminobenzoic acid monoglycerin ester, N, N-dipropoxyparaaminobenzoic acid ethyl ester, N, N-diethoxyparaaminobenzoic acid ethyl ester, N, N-dimethylparaaminoethyl ethyl ester Benzoic acid-based ultraviolet absorbers such as esters, N, N-dimethylparaaminobenzoic acid butyl ester, N, N-dimethylparaaminobenzoic acid ethyl ester; anthranilic acid-based ultraviolet absorbers such as homomenthyl-N-acetylanthranilate; salicylic acid And salicylic acid purples such as sodium salts thereof, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate, etc. Octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p- Methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, 2-ethylhexyl p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (cinoxate), Cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl α-cyano-β-phenylcinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxysi Cinnamic acid-based ultraviolet absorbers such as namate, ferulic acid and derivatives thereof; 2,4-dihydroxybenzophenone, 2,2′-dihydroxy-4-methoxybenzophenone, 2,2′-dihydroxy-4,4′-dimethoxybenzophenone; 2,2 ', 4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone -5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4′-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone and the like Benzophenone purple Linear absorber; 3- (4'-methylbenzylidene) -d, l-camphor; 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5- Methylphenylbenzotriazole; 2- (2'-hydroxy-5'-t-octylphenyl) benzotriazole; 2- (2'-hydroxy-5'-methylphenylbenzotriazole; dibenzarazine; dianisoylmethane; 5- (3 2,3-dimethyl-2-norbornylidene) -3-pentan-2-one; dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane; octyltriazone; urocanic acid derivatives such as urocanic acid and ethyl urocanate; 2- (2'-hydroxy-5'-methylphenyl) benzotriazole, 1- ( , 4-dimethoxyphenyl) -4,4-dimethyl-1,3-pentanedione, hydantoin derivatives such as 2-ethylhexyl dimethoxybenzylidene dioxoimidazolidine propionate, phenylbenzimidazozole sulfonic acid, terephthalidene dicane fursulfone Preferred are acids, drometrizole trisiloxane, methyl anthranilate, rutin and its derivatives, and oryzanol and its derivatives.

  As vitamins and derivatives thereof, vitamin A such as retinol, retinol acetate, retinol palmitate; thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, Flavin adenine dinucleotide, cyanocobalamin, folic acids, nicotinic acids such as nicotinamide / benzyl nicotinate, vitamin Bs such as choline; vitamin Cs such as ascorbic acid and salts thereof such as sodium; vitamin D; Vitamin E such as β, γ, δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphate salts such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; Fatty acid esters of ascorbic acid, such as tetraisopalmitic acid ester, ascorbyl stearate, ascorbyl palmitate, and ascorbyl dipalmitate; ascorbic acid alkyl ethers, such as ethyl ascorbic acid; ascorbic acid glucosides, such as ascorbic acid-2-glucoside; Ascorbic acid derivatives such as fatty acid esters and tocopheryl ascorbyl phosphate; vitamin derivatives such as tocopherol derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol linoleate, tocopherol ferulate and tocopherol phosphate; tocotrienol; and other various vitamin derivatives Are preferred.

  Anti-inflammatory and anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramin hydrochloride, chlorpheniramine maleate; And a plant extract such as Yongba extract are preferred. Examples of hair-growth agents, blood circulation promoters, and stimulants include plant extracts and tinctures such as assembly extract, pepper tincture, ginger tincture, ginger extract, and cantharis tincture; capsaicin, nonylate valenylamide, zingerone, ictamol, tannic acid , Borneol, cyclanderate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthin, γ-oryzanol, cepharanthin, vitamin E and derivatives such as tocopherol nicotinate / tocopherol acetate, γ-oryzanol, nicotinic acid and nicotinamide / benzyl nicotinate Derivatives such as ester inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, Flavanonol derivatives, stigmasterol or stigmasteranol and glycosides thereof, and minoxidil are preferred. Preferred examples of hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone, and the like. Other therapeutic agents such as anti-wrinkle agents, anti-aging agents, tightening agents, cooling agents, warming agents, wound healing promoters, stimulants, analgesics, cell activators, etc. include retinols, retinoic acids, retinoin Acid tocopheryl; derivatives of lactic acid, glycolic acid, gluconic acid, fruit acid, salicylic acid and glycosides / esterified products thereof, hydroxy-capric acid, long-chain α-hydroxy fatty acid, α- such as long-chain α-hydroxy fatty acid cholesteryl, etc. β-hydroxy acids and derivatives thereof; γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine, and derivatives thereof; coenzyme Q10, carotene, lycopene , Astaxanthin, lutein, α-lipoic acid, platinum nanocolloid, fullerenes, etc. Catechins; flavones such as quercetin; isoflavones; gallic acid and ester sugar derivatives; tannins, sesamin, protoanthocyanidins, chlorogenic acid, polyphenols such as apple polyphenols; rutin and glycosides; Derivatives of hesperidin and glycosides; lignan glycosides; licorice extract-related substances such as glabridine, glabrene, liquiritin, isoliquiritin; lactoferrin; gingerol, gingerol; fragrance substances such as menthol, camphor, cedrol and derivatives thereof. Preferred are capsaicin, vanillin and the like and derivatives; insect repellents such as diethyltoluamide; complexes of a physiologically active substance and cyclodextrins.

  Plant / animal / microbial extracts include iris extract, ashitaba extract, asnaro extract, asparagus extract, avocado extract, amateur extract, almond extract, altea extract, arnica extract, aloe extract, apricot extract, apricot nucleus extract, and ginkgo extract , Inchiko extract, Fennel extract, Turmeric extract, Oolong tea extract, Owaurushi extract, Eijitsu extract, Echinashi leaf extract, Emisoso extract, Japanese gourd extract, Oubaku extract, Ouren extract, Barley extract, Panax ginseng extract, Hypericum perforatum extract, Odorikosou extract, Ononisu extract , Dutch mustard extract, orange extract, dried seawater, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, hydrolyzed Luk, cuckoo extract, chamomile extract, oil-soluble chamomile extract, carrot extract, sagebrush extract, oak wheat extract, calcade extract, licorice extract, oil-soluble licorice extract, kiwi extract, kio extract, jellyfish extract, kina extract, cucumber extract, kiri leaf extract, Guanosine, Guava extract, Kujin extract, Gardenia extract, Kumazasa extract, Clara extract, Walnut extract, Chestnut extract, Grapefruit extract, Clematis extract, Black rice extract, Brown sugar extract, Black vinegar, Chlorella extract, Mulberry extract, Gentian extract, Gennoshoko extract, Black tea Extract, yeast extract, kouboku extract, coffee extract, burdock extract, rice extract, rice fermented extract, rice bran fermented extract, rice germ oil, comfrey extract, Lagen, lingonberry extract, Psychic extract, Psychoextract, Saitai extract, saffron extract, Salvia extract, Sabonso extract, Sasa extract, Hawthorn extract, Sansha extract, Sansho extract, Shiitake extract, Jio extract, Shikon extract, Perilla extract, Shinanoki extract, Shimotsubesou Extract, Jatoba extract, Peony extract, Ginger extract, Shobu root extract, Birch extract, White jellyfish extract, Japanese horse chestnut extract, Stevia extract, Stevia fermented product, Nishikawayanagi extract, Sekiyu suta extract, Scotch hawthorn extract, Syringa serrata extract, Scotch extract , Mint extract, sage extract, mallow extract, senkyu extract, assembly extract, soybean extract, rhubarb extract, die Extract, syrup extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, scotch extract, chimpanzee extract, tea tree oil, tea bean extract, capsicum extract, eucalyptus extract, calendula extract, spruce extract, spruce extract, dokudami extract, tomato Extract, natto extract, carrot extract, garlic extract, nobara extract, hibiscus extract, Bacmondou extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, Parietaria extract, Hioki sorghum extract, bisabolol, hinoki extract, bifidobacterium extract, Loquat extract, coltsfoot extract, fukinotou extract, bakuria extract, butcher bloom extract, grape extract, grape seed extract, propolis, loofah extract, Safflower extract, Peppermint extract, Bodaiju extract, Button extract, Hop extract, Maikaika extract, Pine extract, Maronie extract, Mizubasho extract, Mukuroji extract, Melissa extract, Mozuku extract, Peach extract, Cornflower extract, Eucalyptus extract, Yukinoshita extract, Yuzu extract, Lily extract, Yokuinin extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, litchi extract, lettuce extract, lemon extract, forsythia extract, astragalus extract, rose extract, rosemary extract, roman chamomile extract, royal jelly Extracts and extracts such as Warmoko extract are preferred.

  Examples of the antipruritic include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitor and the like. Examples of the exfoliating / dissolving agent include salicylic acid, sulfur, resorcin, selenium sulfide, and pyridoxine. Examples of antiperspirants include chlorohydroxyaluminum, aluminum chloride, zinc oxide, zinc paraphenolsulfonate, and the like. Examples of the cooling agent include menthol and methyl salicylate. Examples of astringents include citric acid, tartaric acid, lactic acid, aluminum / potassium sulfate, tannic acid, and the like. Examples of the enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease and the like. Preferred nucleic acids include ribonucleic acid and its salts, deoxyribonucleic acid and its salts, and disodium adenosine triphosphate.

  As the fragrance, acetyl cedrene, amyl cinnamaldehyde, allyl amyl glycolate, β-ionone, IsoE super, isobutyl quinoline, iris oil, iron, indole, ylang-ylang oil, undecanaal, undecenal, γ-undecalactone, Estragole, Eugenol, Okemos, Opoponax Resinoid, Orange Oil, Eugenol, Orlanthol, Garrack Solid, Carvacrol, L-Carbon, Camphor, Cannon, Carrot Seed Oil, Clove Oil, Methyl Cinnarate, Geraniol, Geranilnitrile , Isobornyl acetate, geranyl acetate, dimethylbenzylcarbinyl acetate, styralyl acetate, ceryl acetate, terpinel acetate, pt-butylcyclohexyl acetate, vetiveryl acetate, benzyl acetate, vinegar Linalyl, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromyrcenol, jasmine absolute, jasmine lactone, cis-jasmon, citral, citronenol, citronellal, Cinnamon bark oil, 1,8-cineole, cinnamaldehyde, stylax resinoid, cedarwood oil, cedren, cedrol, celery seed oil, thyme oil, damascon, damasenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, Tripral, nerol, nonanal, 2,6-nonadienol, nonalactone, patchouli alcohol, vanilla absolute , Vanillin, basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperiton, phenethyl alcohol, phenylacetaldehyde, petitgren oil, hexylcinnamaldehyde, cis-3-hexenol, peruval balsam, vetiver oil, vetiverol, peppermint oil, Pepper oil, heliotropin, bergamot oil, benzyl benzoate, borneol, milresinoid, musk ketone, methylnonylacetaldehyde, γ-methylyonone, menthol, L-menthol, L-menthon, eucalyptus oil, β-yonone, lime oil, lavender oil, Synthetic and natural flavors such as D-limonene, linalool, linal, liliar, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils, and various compounded flavors It is mentioned as preferred.

  Examples of the pigment / colorant / dye / pigment are Brown No. 201, Black No. 401, Purple No. 201, Purple No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 202, Blue No. 203, Blue No. 204 Blue No. 205, Blue No. 403, Blue No. 404, Green No. 3, Green No. 201, Green No. 202, Green No. 204, Green No. 205, Green No. 3, Green No. 401, Green No. 402, Red No. 102, Red 104-1, red 105-1, red 106, red 2, red 3, red 201, red 202, red 203, red 204, red 205, red 206, red 207 Red 208, Red 213, Red 214, Red 215, Red 218, Red 219, Red 220, Red 221, Red 223, Red 225, Red 226, Red 227, Red 227 No. 28, Red 230-1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503 Red 504, Red 505, Red 506, Orange 201, Orange 203, Orange 204, Orange 205, Orange 206, Orange 207, Orange 401, Orange 402, Orange 403, Yellow 201, Yellow 202-1, Yellow 202-2, Yellow 203, Yellow 204, Yellow 205, Yellow 4, Yellow 401, Yellow 402, Yellow 403-1, Yellow 404, Yellow Legal pigments such as No. 405, Yellow 406, Yellow 407, Yellow No. 5, etc .; Other acidic dyes such as Acid Red 14; Base dyes such as Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, Arianor Straw Yellow; Two , Nitro dyes such as HC Yellow 5, HC Red 3, 4-hydoxypropylamino-3-nitrophenol, N, N'-bis (2-hydroxyethyl) -2-nitro-p-phenylenediamine, HC Blue 2, and Basic Blue 26; dispersion Dyes; inorganic white pigments such as titanium dioxide and zinc oxide; inorganic red pigments such as iron oxide (iron oxide) and iron titanate; inorganic brown pigments such as γ-iron oxide; inorganic yellow pigments such as yellow iron oxide and loess Pigments; inorganic black pigments such as black iron oxide and lower titanium oxide; inorganic purple pigments such as mango violet and cobalt violet; inorganic green pigments such as chromium oxide, chromium hydroxide, and cobalt titanate; ultramarine, navy blue, etc. Inorganic blue pigments: pearl pigments such as titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil; aluminum powder Metal powder pigments such as powdered powders and gold; astaxanthin, anthraquinones such as alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, calsamine, quercetin, crocin, chlorophyll, curcumin, cochineal, naphthoquinones such as shikonin, bixin, Flavones, betacyanidins, henna, hemoglobin, lycopene, riboflavin, rutin, and other natural pigments and dyes; p-phenylenediamine, toluene-2,5-diamine, o-, m-, or p-aminophenol, m-phenylene Oxidation dye intermediates and couplers such as diamine, 5-amino-2-methylphenol, resorcin, 1-naphthol, 2,6-diaminopyridine and the like; salts; autoxidation dyes such as indoline; dihydroxyacetone; And the like as correct ones.

  Preferred examples of the water include hard water, soft water, natural water, deep sea water, electrolytic alkali ion water, electrolytic acidic ion water, ion water, and cluster water, in addition to ordinary water and purified water.

  In addition to these, cosmetic raw material standards, cosmetic varieties compounding component standards, Japanese Cosmetic Industry Federation ingredient label list, INCI dictionary (The International Cosmetic Ingredient Dictionary and Handbook), quasi-drug raw material standards, Japanese Pharmacopoeia, pharmaceutical additives Ingredients listed in the standards, official compendiums of food additives, etc., and Japanese and foreign patent publications and patent publications (including published publications and republication) that belong to the international patent classification IPC A61K7 and A61K8 Known cosmetic components, pharmaceutical components, food components, and the like, such as the components described, can be contained in a known combination and in a blending ratio and blending amount.

  Examples of the types of the cosmetics of the present invention include hair cosmetics, skin cosmetics, makeup cosmetics, aromatic cosmetics, body cosmetics, and external skin preparations such as ointments. The cosmetic of the present invention can be produced according to a usual method.

  The types of the cosmetic or the external preparation for skin of the present invention will be described in further detail.Examples of hair cosmetics include oil shampoos, cream shampoos, conditioning shampoos, dandruff shampoos, shampoos for hair coloring, and shampoos with integrated rinse. Rinsing, treatment, hair pack, hair foam, hair mousse, hair spray, hair mist, hair wax, hair gel, water grease, set lotion, color lotion, hair tonic, hair liquid, pomade, chick, hair cream, hair blow, split ends coat , Hair oil, permanent wave agent, straight perm agent, oxidative hair dye, hair bleach, hair color pre-treatment, hair color after treatment, perm pre-treatment, perm Terpolymers treatments, hair manicure, and as hair growth agents are preferred.

  As skin cosmetics, lotions such as soft lotion, astringent lotion, washing lotion, and multi-layer lotion; emollient lotion, moisturizing lotion, milky lotion, nourishing lotion, nourishing milk, skin moisture, moisturizer -Emulsions, massage lotions, cleansing lotions, protect emulsions, sun protects, sun protectors, UV care milk, sun screens, make-up lotions, keratin smoothers, elbow lotions, hand lotions, body lotions, etc .; emollient creams, nutritional creams, Nourishing cream, burnishing cream, moisture cream, night cream, massage cream, cleansing cream, makeup cream, base cream Creams, such as creams, pre-make-up creams, sunscreen creams, suntan creams, depilatory creams, deodorant creams, shaving creams, keratin softening creams; gels, such as moisture gels; essences, such as moisturizing essences, whitening essences, ultraviolet protection essences; Liposomal cosmetics such as liposome serum and liposome lotion; pack masks such as peel-off pack, powder pack, washing pack, oil pack, cleansing mask; cleansing foam, cleansing cream, cleansing milk, cleansing lotion, cleansing gel, cleansing Oil, cleansing mask, washing powder, facial cleansing powder, etc .; toilet soap, transparent soap, medicated soap, liquid soap, shaving soap, synthetic toilet soap Soap can be mentioned as preferred.

  As make-up cosmetics, preferred are white powder and powdered powders, foundations, lipsticks, lip gloss, blusher, eyeliner, mascara, eye shadow, eyebrows, eyebrow, nail enamel, enamel remover, nail treatment. .

  Preferred examples of the aromatic cosmetics include perfume, perfume, parfum, eau de parfum, eau de toilette, eau de cologne, condensed fragrance, aromatic powder, perfume soap, body lotion, and bath oil.

  Examples of body cosmetics include body cleaning products such as body shampoos, deodorant lotions, deodorant powders, deodorant sprays, deodorant cosmetics such as deodorant sticks, decolorizing agents, depilatory and depilatory agents, bath agents, and insect repellent sprays. Repellers are preferred.

  The external preparation for skin can be used in the form of ointments, patches, lotions, liniments, liquid coatings and the like. In addition, it can be used as an oral cosmetic such as toothpaste and mouthwash.

  Examples of the cosmetic formulation of the present invention include oil-in-water (O / W), water-in-oil (W / O), W / O / W, and O / W / O emulsions. Oily cosmetics, solid cosmetics, liquid cosmetics, kneaded cosmetics, stick cosmetics, volatile oil cosmetics, powdery cosmetics, jelly cosmetics, gel cosmetics, paste cosmetics, emulsified Preferred forms include polymer cosmetics, sheet cosmetics, mist cosmetics, and spray cosmetics.

  The present invention will be described in more detail with reference to the following examples, but the present invention is not limited thereto.

Synthesis Example 1 Synthesis of distearyl malate of the present invention 80 g (0.597 mol) of DL-malic acid, 323 g of stearyl alcohol (octadecanol) were placed in a 1 L reactor equipped with a stirrer, a thermometer, and a gas inlet tube. .193 mol) and 149 g of heptane as a solvent were heated to 100 ° C. to 120 ° C. while blowing nitrogen, and refluxed for 6 hours. After completion of the reaction, unreacted carboxylic acid is washed away with water with an aqueous sodium hydroxide solution, the organic layer is concentrated, and then steam deodorization is performed under reduced pressure to give 375 g (98% yield) of the desired distearyl malate as a white solid oil. (Melting point 60 ° C.).

Comparative Synthesis Example 1 Synthesis of Conventional Diisostearyl Malate In a 3 L reactor equipped with a stirrer, a thermometer, and a gas inlet tube, 220 g (1.64 mol) of DL-malic acid, 5,7,7-trimethyl-2 -889 g (3.28 mol) of-(1,3,3-trimethylbutyl) -octane-1-ol (isostearyl alcohol: fine oxocol 180 (manufactured by Nissan Chemical Industries, Ltd.)) and 231 g of heptane as a solvent were charged. Then, the mixture was heated to 100 ° C. to 120 ° C. while blowing nitrogen, and refluxed for 6 hours. After the completion of the reaction, unreacted carboxylic acid is washed with water with an aqueous sodium hydroxide solution, and the organic layer is concentrated. Obtained as a viscous liquid oil.

<Lamellar forming ability>
With respect to the malate ester obtained in Synthesis Example 1 and Comparative Synthesis Example 1, the lamellar forming ability was evaluated by the following method using a polarizing microscope.

Evaluation method 1 g of each malic acid ester and 1 g of water were mixed in a mortar and hydrated. A small amount of this hydrate was placed on a slide glass, and the product sandwiched between cover glasses was observed with a polarizing microscope. The lamellar forming ability was evaluated by the presence or absence of a maltese cloth image showing the formation of lamellar spherulites.

  FIG. 1 shows a polarizing microscope image of the malate ester of the present invention of Synthesis Example 1. In FIG. 1, many maltese cloth images were observed, and it was clear that the malate ester of the present invention has excellent lamellar forming ability. Note that no maltese cross image was observed for diisostearyl malate of Comparative Synthesis Example 1.

  A cosmetic was prepared by blending the malic ester of Synthesis Example 1 with the following formulation. All of the obtained cosmetics have excellent feeling of use, skin cosmetics have excellent moisturizing properties, makeup cosmetics have excellent gloss and color development, and hair cosmetics have excellent finger and moisturizing properties. It could give a feeling.

Example 1 Moisturizing Lip When a moisturizing lip having the following formulation was moistened with water, a Maltese cloth image could be confirmed with a polarizing microscope.

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Malate ester of Synthesis Example 1 10.0
Neosolue-DiSM (Nippon Seika) Amount that totals 100 Hydrogenated polyisobutene 15.0
Planool-G (Nippon Seika) 10.0
Planool-MAS (Nippon Seika) 5.0
Microcrystalline wax 3.0
Polyethylene wax 5.0
Polyamide-3 5.0
Sucrose tetrastearate triacetate 5.0
Methyl paraben 0.1
BHT 0.01
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
All components were melted by heating and mixed uniformly.

Example 2 Emulsion

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Glycerin 3.0
Diglycerin 1.0
BG 7.0
Phytocompo-C (Nippon Seika) 1.0
Hydrogenated lysolecithin (Nippon Seika) 0.1
Part B Malic ester of Synthesis Example 1 1.0
Planool-MAS (Nippon Seika) 0.5
Planool-LG1 (Nippon Seika) 0.5
Triethylhexanoin (Nippon Seika) 3.0
Hydrogenated polyisobutene 3.5
Cyclopentasiloxane 1.0
Isododecane 1.5
Cetostearyl alcohol 1.0
Jojoba alcohol 3.0
Part C (hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer
0.2
Tremoist-TP (Nippon Seika) 0.03
Carbomer 0.1
Purified water 20.0
D part Neosolue-AquaS (Nippon Seika) 0.5
Phytopresome MEL (Nippon Seika) 0.5
Polyquaternium-51 1.0
Pyrrolidone carboxylate Na 0.1
Xylitol 0.5
Erythritol 0.5
Water-soluble collagen 0.2
Potassium hydroxide 0.2
Phenoxyethanol 0.2
Methyl paraben 0.15
Purified water Amount to be 100 in total ---------------------------------------------------------------------------------
(Preparation method)
Parts A, B, and D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to obtain a viscous liquid. Part A was added while stirring Part A with a homodisper, and then Part D was added and emulsified. At about 50 ° C., part C was added, and the mixture was stirred and cooled to about 40 ° C.

Example 3 Whitening Emulsion

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 1.0
Planool-DP (Nippon Seika) 1.0
Cetyl ethylhexanoate (Nippon Seika) 5.0
Cetanol 1.2
Dimethicone 10cS 3.0
Ethyl paraben 0.1
Octyldodecanol 2.0
Oleyl alcohol 1.0
Part B Stearoxyhydroxypropyl methylcellulose 0.05
Tremoist-TP (Nippon Seika) 0.03
Xanthan gum 0.1
Purified water 20.0
Part C Phytocompo-PP (Nippon Seika) 1.0
Pentylene glycol 3.0
Glycerin 8.0
Part D 3-O-ethylascorbic acid (Nippon Seika) 1.0
Arbutin (Nippon Seika) 1.0
Tranexamic acid (Nippon Seika) 1.0
Purified water 20.0
Part E Phenoxyethanol 0.2
Methyl paraben 0.15
Na pyrosulfite 0.05
Phytic acid 0.2
Citric acid 0.1
Amount of Na citrate to reach pH 4.5 Purified water Amount of total to 100 -------------------- −−−−−−
(Preparation method)
Parts A and E were each heated to about 70 ° C. and uniformly dissolved. Part B was stirred to obtain a viscous liquid. Part C was heated to about 70 ° C. and uniformly dispersed. Part A was added while stirring Part C with a homodisper, and then Part E was added while stirring. Part D and Part B were added at about 50 ° C., and the mixture was stirred and uniformly dissolved.

Example 4 Skin care cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Glycerin 9.0
DPG 5.0
Phytocompo-PP (Nippon Seika) 1.0
Part B Malate ester of Synthesis Example 1 2.0
Vaseline 10.0
Planool-SUN (Nippon Seika) 1.0
Pentaerythrityl tetraisostearate 5.0
Polyglyceryl diisostearate-2 2.0
Polyglyceryl triisostearate-2 1.0
Stearoyl phytosphingosine 0.05
Part C Carbomer 0.1
Hydroxide K 0.07
Hyaluronate Na 0.1
Xanthan gum 0.1
Purified water 10.0
D part betaine 0.1
Niacinamide 0.1
Phenoxyethanol 0.4
Ethylhexyl glycerin 0.2
Methyl paraben 0.05
Purified water Amount to be 100 in total ---------------------------------------------------------------------------------
(Preparation method)
Parts A, B, and D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to obtain a viscous liquid. Part A was added while stirring Part A with a homodisper, and then Part D was added and emulsified. At about 50 ° C., part C was added, and the mixture was stirred and cooled to about 40 ° C.

Example 5 Skin care cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 2.0
Squalane 8.0
Stearic acid 1.0
Planool-ISS (Nippon Seika) 1.0
Phytosterol 0.2
Macadamia nut oil 3.0
Sunflower oil 2.0
Ethyl oleate 1.0
Polysorbate 80 0.5
Olive oil fatty acid sorbitan 0.2
Polyglyceryl diisostearate-2 2.0
Polyglyceryl oleate-10 1.0
Part B Acrylic acid / alkyl methacrylate copolymer 0.1
Hydroxide K 0.07
(Acrylic acid / alkyl acrylate (C10-30)) copolymer 0.1
(Na acrylate / acryloyldimethyltaurine) copolymer 0.1
Tremoist-SL (Nippon Seika) 1.0
Purified water 10.0
Part C Glycerin 9.0
Propanediol 10.0
Oligopeptide-24 0.05
PEG-30 0.5
PEG-8 5.0
Methyl paraben 0.1
Phenoxyethanol 0.3
Purified water Amount to be 100 in total ---------------------------------------------------------------------------------
(Preparation method)
Parts A and C were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to obtain a viscous liquid. Part A was added and emulsified while stirring Part C with a homomixer. After cooling, at about 50 ° C., Part B was added, and the mixture was stirred and cooled to about 40 ° C.

Example 6 Skin care cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 2.0
Planool-MAS (Nippon Seika) 2.0
Planpool-LG1 (Nippon Seika) 1.0
Candelilla wax 1.0
Shea butter 3.0
Squalane 8.0
Cetanol 1.8
Behenyl alcohol 1.5
Hydrogenated lecithin 0.3
Glyceryl stearate 1.0
Sorbitan stearate 1.0
Polyglyceryl oleate-10 1.0
PEG-stearic acid 0.5 0.5
Part B Xanthan gum 0.1
Hydroxyethyl cellulose 0.1
Microcrystalline cellulose powder 0.3
Stearoxyhydroxypropyl methylcellulose 0.1
Tranexamic acid 0.5
Purified water 20.0
Part C Glycerin 8.0
DPG 5.0
Sorbitol 2.0
Neosolue-Aqulio (Nippon Seika) 1.0
Methyl paraben 0.15
Purified water Amount to be 100 in total ---------------------------------------------------------------------------------
(Preparation method)
Parts A and C were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to obtain a viscous liquid. Part A was added and emulsified while stirring Part C with a homomixer. After cooling, at about 50 ° C., Part B was added, and the mixture was stirred and cooled to about 40 ° C.

Example 7 Skin care cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Glycerin 9.0
Phytocompo-C (Nippon Seika) 1.0
Glucosyl rutin 0.001
Part B Malic ester of Synthesis Example 1 1.0
Ethylhexyl salicylate 1.0
Ethylhexyl methoxycinnamate 1.0
Astaxanthin 0.005
Pentaerythrityl tetraethylhexanoate (Nippon Seika) 0.1
Neopentyl glycol diisostearate 2.0
Planool-S (Nippon Seika) 0.8
Planool-ISS (Nippon Seika) 2.0
Carnauba wax 0.5
Steareth-2 2.5
Steareth-21 1.8
Cetanol 3.0
Tocopherol acetate 0.03
Squalane 3.0
Part C (acrylamide / acryloyldimethyltaurine Na) copolymer 0.1
Carbomer 0.1
Arginine 0.1
Acetylglucosamine 0.2
Ethylhexyl glycerin 0.2
Ethanol 3.0
Purified water 10.0
Panthenol 0.5
Retinol palmitate 0.05
D part methyl paraben 0.15
Purified water Total amount of 100 ----
(Preparation method)
Parts A, B, and D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to obtain a viscous liquid. Part A was added while stirring Part A with a homodisper, and then Part D was added and emulsified. At about 50 ° C., part C was added, and the mixture was stirred and cooled to about 40 ° C.

Example 8 Skin care cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 1.0
Planool-LG1 (Nippon Seika) 0.5
Mineral oil 7.8
Vaseline 7.0
Squalane 1.2
Cholesterol 0.1
Jojoba oil 0.15
Microcrystalline wax 2.4
Paraffin wax 2.0
Distearate Al 0.9
Hydrogenated lecithin 0.2
Hydrogenated polyisobutene 2.8
Lanolin alcohol (Nippon Seika) 2.3
Behenyl alcohol 0.5
Octyldodecanol 3.0
Part B Mg sulfate 0.5
Na benzoate 0.1
Neosolue-Aqua (Nippon Seika) 0.3
Glycerin 3.5
Purified water Amount that totals 100 Part C Mg stearate 0.9
Cyclopentasiloxane 2.5
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Heat and dissolve Part A and Part B, and disperse them uniformly. Part B is gradually added to part A and emulsified. The dispersed Part C is blended and cooled with stirring.

Example 9 Whitening Cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Glycerin 12.0
BG 6.0
Phytocompo-PP (Nippon Seika) 2.5
Part B Malic ester of Synthesis Example 1 3.0
Hydrogenated rapeseed oil 2.0
Planool-LG3 (Nippon Seika) 1.5
Shea butter 1.0
Pentaerythrityl tetraethylhexanoate (Nippon Seika) 3.0
Sucrose stearate 0.8
Cetearyl glucoside 1.2
Behenyl alcohol 1.5
Ascorbyl tetrahexyldecanoate 5.0
Lauroyl sarcosine isopropyl 2.0
Glyceryl diisostearate 1.8
Cetanol 2.5
Sorbitan stearate 0.8
Part C Xanthan gum 0.05
Tremoist-SL (Nippon Seika) 1.0
Lysine dilauroyl glutamate Na 0.2
Succinoglycan 0.15
Water-soluble collagen 0.05
Glucosyl trehalose 0.05
Glycylglycine 0.05
Pyrosulfite Na 0.03
Arbutin (Nippon Seika) 1.0
Tranexamic acid 1.0
D section Neosolu-Aqulio (Nippon Seika) 1.0
Propanediol 3.0
Methyl paraben 0.1
Purified water Total amount of 100 ----
(Preparation method)
Parts A, B, and D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to obtain a viscous liquid. Part A was added while stirring Part A with a homodisper, and then Part D was added and emulsified. At about 50 ° C., part C was added, and the mixture was stirred and cooled to about 40 ° C.

Example 10 Hand cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Squalane 10.0
Vaseline 20.0
Polyglyceryl pentastearate-10 2.0
Microcrystalline wax 4.0
Stearoyl lactate Na 1.3
Al stearate 1.5
Mg stearate 1.0
Stearic acid Ca 0.1
Part B Malic ester of Synthesis Example 1 1.5
Planool-MAS (Nippon Seika) 1.0
Planool-LG2 (Nippon Seika) 0.8
Cetyl ethylhexanoate (Nippon Seika) 5.0
Triethylhexanoin (Nippon Seika) 6.0
Propyl paraben 0.05
Tocopherol 0.05
Cyclopentasiloxane 5.0
Part C Methyl paraben 0.1
Betaine 0.02
Urea 0.01
Neosolue-Aqua (Nippon Seika) 0.1
Glycerin 10.0
Water Amount that totals 100--------------------------
(Preparation method)
Parts B and C were each heated to about 80 ° C. and dissolved. Part A was placed in another container, heated to 100 to 120 ° C, turned into a transparent gel, and cooled to 80 ° C. Part B was added to Part A while stirring, and Part C was further added and emulsified. After uniform mixing, the mixture was cooled to about 40 ° C.

Example 11 Gel lotion

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Phytocompo-PP (Nippon Seika) 0.5
Glycerin 5.0
BG 5.0
Glyceryl behenate 0.8
Malate ester of Synthesis Example 1 0.1
Stearic acid 0.3
PEG-20 hydrogenated castor oil 0.1
Polyglyceryl oleate-10 0.1
Part B Neosolue-Aqulio (Nippon Seika) 1.0
Phenoxyethanol 0.3
Pullulan 0.2
Ethylhexyl glycerin 0.2
Phytopresome MEL (Nippon Seika) 0.2
Methyl gluces-10 0.05
Tremoist-TP 0.1
Gellan gum 0.03
Inulin 0.05
Hydroxyethyl cellulose 0.05
Na hyaluronate 0.01
Carbomer 0.06
Hydroxide K 0.05
Purified water Amount to be 100 in total ---------------------------------------------------------------------------------
(Preparation method)
Part A was heated to about 70 ° C. and uniformly dispersed. Part B was mixed, stirred well, and made uniform, and then heated to about 70 ° C. Part B was added to Part A, and the mixture was stirred at about 70 ° C. using a homomixer and cooled to about 40 ° C.

Example 12 Moisturizing Lotion

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Phytopresome Cera23 (Nippon Seika) 0.5
BG 2.0
Glycerin 3.0
1,2-pentanediol 3.0
Polyglycerin-10 1.0
Malate ester of synthesis example 1 0.05
Part B Purified water 40.0
Part C Neosolue-Aqulio (Nippon Seika) 1.0
Neosolue-AquaS (Nippon Seika) 1.0
Lysine dilauroyl glutamate Na 0.2
Glucosylceramide 0.5
Tremoist-TP (Nippon Seika) 0.1
Acetyl hyaluronate Na 0.0.3
EDTA-2Na 0.05
Phenoxyethanol 0.2
Methyl paraben 0.15
Purified water Amount that totals 100 ----
(Preparation method)
Parts A and B were each heated to 70 ° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, after cooling, part C previously mixed was added to make a uniform liquid.

Example 13 Whitening lotion

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Phytopresome Cera23 (Nippon Seika) 0.5
1,2-pentanediol 5.0
Malate ester of synthesis example 1 0.05
Oryzanol 0.1
Part B Tranexamic acid (Nippon Seika) 2.0
3-O-ethylascorbic acid (Nippon Seika) 1.0
Ascorbic acid 2-glucoside 1.0
Na sulfite 0.05
Phytic acid 0.3
Purified water 20.0
Ohgon Extract 0.2
Peony extract 0.2
Tripropylene glycol 2.0
DPG 2.0
Maltose 1.0
Carbomer 0.01
Glutamic acid 0.2
Phenoxyethanol 0.2
Methyl paraben 0.15
Citric acid 0.1
Na citrate qs Part C Purified water Amount to be 100 in total --------------------------------------------------- −−−−−
(Preparation method)
Part B was mixed to prepare a viscous liquid. Part A and Part C were heated to 70 ° C., and Part A was added while stirring Part C with a homomixer (7000 rpm) to prepare an aqueous dispersion. Further, after cooling, the premixed part B was added to make a uniform liquid.

Example 14 Cosmetic oil

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Squalane Total amount of 100 Ethylhexyl palmitate (Nippon Seika) 10.0
Malate ester of Synthesis Example 1 5.0
Octyldodecanol 40.0
Planool-MAS (Nippon Seika) 2.0
Planool-LG2 (Nippon Seika) 3.0
Ceramide 1 0.005
Ceramide 2 0.05
Ceramide 5 0.05
Stearic acid 0.2
Cholesterol 0.5
Preservative Appropriate amount-------------------------------------------
(Preparation method)
After all the components were stirred and mixed at about 90 ° C., they were allowed to cool.

Example 15 Cleansing Gel

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 1.0
Planool-S (Nippon Seika) 1.0
Planool-LG1 (Nippon Seika) 1.0
LUSPLAN DD-IS (Nippon Seika) 3.0
LUSPLAN PI-DA (Nippon Seika) 0.5
Diethylhexyl sebacate 3.0
Glyceryl tri (caprylate / caprate) 3.0
Cyclomethicone 1.0
Dihydrocholes-30 (Nippon Seika) 2.0
PEG-25 hydrogenated castor oil 10.0
PEG-20 phytosterol 5.0
Octyldecess-20-15.0
Methyl gluces-10 5.0
Glycerin 16.0
BG 5.0
Part B Glycyrrhizic acid 2K 0.3
Neosolue-Aqua (Nippon Seika) 1.0
Phenoxyethanol 0.5
Purified water Amount that totals 100 ----
(Preparation method)
Part A is weighed and heated to about 80 ° C. to dissolve. Weigh part B and heat to about 80 ° C. B was gradually added to A with stirring, and the mixture was cooled to 40 ° C after mixing.

Example 16 Cleansing Cream

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 1.0
Planool-LG2 (Nippon Seika) 1.0
Neosolue-Aqulio (Nippon Seika) 1.0
Ceresin 6.0
Mineral oil 18.0
Diisobutyl adipate (Nippon Seika) 5.0
Dimethicone 20cS 5.0
Behenyl alcohol 1.0
PEG-12 isostearate 3.0
Sorbitan sesquioleate 1.5
Polyoxyethylene sorbitan oleate 0.3
Polyglyceryl laurate-10 0.3
Glyceryl stearate 0.5
Microcrystalline wax 2.0
Tocopherol 0.05
Propyl paraben 0.05
Part B Neosolue-Aqua (Nippon Seika) 0.5
Glycerin 3.0
Diglycerin 5.0
Methyl paraben 0.2
Edetate 3Na 0.02
Phenoxyethanol 0.2
Purified water Amount that totals 100 ----
(Preparation method)
Part A was weighed and heated to about 80 ° C. to dissolve. Weigh part B and heat to about 80 ° C. B was gradually added to A with stirring, and the mixture was cooled to 40 ° C after mixing.

Example 17 Cleansing Oil

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Malate ester of Synthesis Example 1 1.0
Planool-LG2 (Nippon Seika) 2.0
Neosolue-Aqulio (Nippon Seika) 2.0
Cetyl ethylhexanoate (Nippon Seika) 5.0
Diethylhexyl succinate (Nippon Seika) 5.0
Dicapric acid PG 3.0
Mineral oil 14.0
Glycerin 16.0
BG 5.0
Sorbeth-30 tetraoleate 10.0
PEG-8 glyceryl isostearate 12.0
Coconut oil fatty acid PEG-7 glyceryl 12.0
Polyglyceryl diisostearate-2 1.5
(Behenic acid / eicosane diacid) glyceryl 1.5
EDTA-2Na 0.1
Citric acid 0.01
Na citrate 0.09
Purified water Amount that totals 100 ----
(Preparation method)
All components were weighed out and stirred and mixed at room temperature until uniform.

Example 18 Facial cleansing foam

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Stearic acid K 10.0
Palmitic acid K 10.0
Myristate K 10.0
Lauric acid K 4.0
Lauroyl sarcosine isopropyl 0.8
Planool-MAS (Nippon Seika) 0.2
Malate ester of Synthesis Example 1 0.5
PEG 1500 10.0
Glycerin 15.0
Glyceryl monostearate 1.0
PEG-20 glyceryl isostearate 1.0
POE (20) sorbitan monostearate 2.0
Part B Tremoist-SL (Nippon Seika) 1.0
Polyquaternium-7 0.5
Polyquaternium-39 0.5
Glycyrrhizic acid 2K 0.1
Methyl paraben 0.1
Purified water Amount to be 100 in total -----------------
(Preparation method)
Part A was weighed and heated to about 80 ° C. to dissolve. Weigh part B and heat to about 80 ° C. B was gradually added to A with stirring, and the mixture was cooled to 40 ° C after mixing.

Example 19 Facial cleansing foam

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 0.2
(Coconut fatty acid / hydrogenated tallow fatty acid) Na glutamate 30.0
Cocoylglycine K 5.0
Planool-LG2 (Nippon Seika) 0.2
Lysine dilauroyl glutamate Na 0.2
Lauric acid diethanolamide 3.0
Decyl glucoside 0.5
Glycol distearate 0.4
Tocopherol 0.1
PEG-8 5.0
PEG-32 10.0
Glycerin 14.0
Propylparaben 0.1
Part B Methyl paraben 0.2
Polyquaternium-51 1.0
Tremoist-SL (Nippon Seika) 0.5
Microcrystalline cellulose 0.3
Polyquaternium-7 0.8
Purified water Amount that totals 100 ----
(Preparation method)
Part A was weighed and heated to about 80 ° C. to dissolve. Weigh part B and heat to about 80 ° C. B was gradually added to A with stirring, and the mixture was cooled to 40 ° C after mixing.

Example 20 Body shampoo

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Malate ester of Synthesis Example 1 0.15
Planool-LG2 (Nippon Seika) 0.05
Cocoyl methyl taurine Na 10.0
Lauroyl hydrolyzed silk Na 6.0
Lauroylmethylalanine Na 10.0
Coco Amphoacetic Acid Na (30%) 4.0
Cocamidopropyl betaine (30%) 10.0
Olefin (C14-16) sodium sulfonate 5.0
Polyquaternium-10 1.3
Guar hydroxypropyltrimonium chloride 0.8
Acetyl hyaluronate Na 0.02
Cocamide DEA 3.0
Hydroxyethyl cellulose 0.05
Glycerin 5.0
Methyl paraben 0.2
Purified water Amount that totals 100 ----
(Preparation method)
All components were heated at about 80 ° C. and uniformly stirred and mixed.

Example 21 Hand soap

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Nacoyl isethionate Na 1.0
Glycerin 50.0
Malate ester of Synthesis Example 1 0.1
Part B Lauroyl sarcosine salt 12.0
Myristoyl methyl taurine sodium 2.0
Polyglyceryl-6 laurate 2.0
Coconut oil fatty acid diethanolamide 2.0
PEG-7 coconut oil fatty acid glyceryl 2.0
Synthetic latex 0.1
Nitrocellulose 0.1
Sorbitol 8.0
Conchiolin degrading peptide 0.1
1,3-butylene glycol 8.0
Phenoxyethanol 0.8
Purified water Amount that totals 100 ----
(Preparation method)
Part A was heated to about 80 ° C. and dissolved. Part B was added to Part A, and the mixture was heated to about 80 ° C., uniformly dissolved, and then cooled.

Example 22 Hair Treatment Without Rinse

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 0.5
Polyquaternium-37 2.0
Squalane 2.0
PPG-3 caprylyl ether 2.0
Microcrystalline wax 0.1
Lanolin alcohol 0.2
Montan wax 0.1
Polyethylene wax 0.1
Beeswax 0.1
Mokuro 0.2
Ceresin 0.1
Dicapric acid PG 1.0
Almond oil 0.5
Ethylhexyl ethylhexanoate 1.0
Candelilla wax extract 0.1
Octyldodecyl erucate 4.5
Tocopherol acetate 0.02
Elcalacton MCT (Nippon Seika) 2.0
Dipentaerythrityl tripolyhydroxystearate 1.5
PPG-5 phytosteryl 0.5
Glycerin 4.0
Sorbitol 2.0
Phenoxyethanol 0.5
Part B Hydrolyzed conchiolin 0.1
Panthenol 0.1
Hydroxypropyltrimonium hyaluronate 0.01
Polyquaternium-11 0.2
Glycosyl trehalose 0.1
Glyceryl glucoside 0.3
Arginine 0.1
Part C Purified water Total amount to be 100 Hydroxypropyl starch phosphate 1.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part C was uniformly dispersed and heated to about 80 ° C. Next, part A was heated to about 80 ° C. to dissolve it. Part A was added while stirring Part C, and after uniform mixing, the mixture was cooled to about 40 ° C. Next, Part B was added and mixed uniformly.

Example 23 Scalp / Hair Treatment Without Rinse

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 1.0
Neosolue-Aqulio (Nippon Seika) 1.0
Ethanol 40.0
Glycyrrhetinic acid 0.02
PPG-3 caprylyl ether 0.3
Elcalacton DES (Nippon Seika) 1.5
PEG / PPG-20 / 20 dimethicone 0.2
PEG-12 dimethicone 0.4
Hydrogenated retinol 0.1
Pyridoxine trishexyldecanoate 0.05
Bisglyceryl ascorbic acid 0.3
Hexyl 3-glyceryl ascorbic acid 0.3
Part B Triethanolamine 0.1
Purified water Total amount of 100 (Acrylates / alkyl acrylate (C10-30)) Crosspolymer 0.4
Carbomer 0.05
Tremoist-SL (Nippon Seika) 1.0
Ammonium acryloyldimethyltaurate / VP) copolymer 0.05
(Acryloyldimethyl taurine ammonium / beheneth-25 methacrylate) Crosspolymer 0.1
Hydroxypropyl chitosan 0.1
Methyl paraben 0.1
Phenoxyethanol 0.2
Part C 3-O-ethylascorbic acid (Nippon Seika) 0.05
Nicotinamide 0.3
Pyridoxine hydrochloride 0.1
Caffeine 0.1
Glucosyl trehalose 0.1
Purified water 10.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part A was heated to about 50 ° C. and dissolved. Next, part B was uniformly dispersed to obtain a viscous liquid. Part A was added to Part B while stirring, and mixed uniformly. Next, part C was added and mixed uniformly.

Example 24 Non-silicone hair treatment

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 1.0
Cetearyl alcohol 3.0
PPG-1 / PEG-1 stealamine 0.8
Behenamidopropyl dimethylamine 1.0
Ethylhexyl palmitate (Nippon Seika) 1.0
Dextrin palmitate 0.5
Inulin stearate 0.5
LUSPLAN SR-DM4 (Nippon Seika) 0.1
Neosolue-DE (Nippon Seika) 1.0
Planool-DP (Nippon Seika) 1.0
Elcalacton DES (Nippon Seika) 1.0
Diethylhexyl succinate (Nippon Seika) 1.0
DPG 1.8
Glycerin 4.0
Mineral oil 0.5
PEG-160M 0.5
Rice bran wax 1.0
Part B hydroxylated lecithin 0.2
Lactic acid 0.3
Hydrolyzed starch 0.4
Hyaluronate Na 0.05
Tremoist-SL (Nippon Seika) 1.0
Hydroxypropyl methylcellulose 0.1
Purified water Amount to be 100 in total Part C Polyquaternium-107 0.5
Neopentyl glycol diheptanoate 2.0
Ethylhexyl isononanoate 1.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part B was heated to about 80 ° C. and uniformly dissolved. Part A was added to another container, heated and dissolved. Part B was gradually added to Part A, mixed uniformly, and cooled. Part C was added at about 50 ° C. and mixed uniformly.

Example 25 Dandruff shampoo

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 0.1
Lauroylmethylalanine Na (30%) 13.0
Cocamidopropyl betaine (30%) 20.0
Cocoyl glutamate TEA (30%) 5.0
Cocamide DEA 1.0
Glycerin 1.0
Glyceryl caprylate 0.4
Glyceryl undecylenate 0.1
Neosolue-AquaS (Nippon Seika) 1.0
Oleic acid 0.2
Sorbitol 1.6
Miconazole nitrate 0.75
Glycol distearate 1.5
Polyquaternium-7 0.3
Part B Na benzoate 0.4
Na chloride 0.2
Purified water Total amount to be 100 Part C Assembly extract 3.0
Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Polyquaternium-47 0.1
Pirocton olamine 0.1
Purified water 9.7
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part B was heated to about 80 ° C. and uniformly dissolved. Part A was placed in another container, heated and dissolved. Part B was gradually added to Part A, mixed uniformly, and Part C was added at about 60 ° C.

Example 26 Shampoo

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 0.2
PPG-3 caprylyl ether 0.2
Ammonium laureth sulfate 5.0
Sodium laureth sulfate (25%) 10.0
Lauryl hydroxysultaine (30%) 10.0
Lauric acid K 1.0
Glycol distearate 0.5
Toluenesulfonic acid 0.3
Stearoxypropyldimethylamine 0.5
PPG-17 0.3
Dimethicone 0.1
PEG-9 dimethicone 0.1
Amodimethicone 0.1
Diethylhexyl sebacate (Nippon Seika) 1.0
Neopentyl glycol diethylhexanoate 0.4
Lanolin fatty acid 0.3
Isodecyl glyceryl ether 0.4
Miconazole nitrate 0.75
Cocamide MEA 1.0
Laureth-4 0.3
Laureth-16 0.2
Steareth-6 0.2
Phenoxyethanol 0.3
Part B Malic acid 0.1
Methyl paraben 0.2
Phosphoric acid 0.03
Na benzoate 0.3
Purified water Amount to be 100 in total Part C Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Tremoist-SL (Nippon Seika) 3.0
Purified water 6.7
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part A was uniformly mixed at about 80 ° C. Part B, which was set aside, was heated to about 60 ° C. and made uniform. Part B was gradually added to Part A while stirring, mixed uniformly, and then cooled to about 50 ° C. Part C was further added and mixed uniformly.

Example 27 Lipstick

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Malate ester of Synthesis Example 1 5.0
LUSPLAN SR-DP4 (Nippon Seika) 7.0
Hydrogenated polyisobutene 5.0
Trioctanoin 10.0
Glyceryl tri (caprylic / capric acid) amount to add up to 100 Dialkyl carbonate (C14, 15) 3.0
Dextrin palmitate 0.9
Dimethylsilylated silica 1.2
Stearoyl lactate Na 0.9
Cetyl octanoate 24.0
Dimethicone 5.0
Planool-MAS (Nippon Seika) 2.0
Planool-G (Nippon Seika) 2.0
Planool-DP (Nippon Seika) 2.0
Ceresin 8.5
Candelilla Row 4.0
Sorbitan sesquioleate 0.15
Hydrogen dimethicone 2.0
Ethanol 0.1
Tocopherol 0.5
Nylon-12 2.0
(Ethylene / propylene) copolymer 0.5
Sulfuric acid Ba 1.0
Iron oxide 2.0
Mica 2.0
Titanium oxide 1.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
After heating, stirring and mixing all the components uniformly, they were filled in a mold and quenched.

Example 28 Lipstick

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Diphenylmethylsiloxyphenylmethicone /
Phenylsilsesquioxane) crosspolymer 15.0
Tri (caprylic / capric) glyceryl 10.0
Malate ester of Synthesis Example 1 5.0
Triethylhexanoin (Nippon Seika) Total amount of 100 Trimethylolpropane triethylhexanoate (Nippon Seika) 3.0
Neosole-DE (Nippon Seika) 0.2
Neosolue-MP (Nippon Seika) 0.2
Isohexadecane 8.0
Isotridecyl isononanoate 8.0
Microcrystalline wax 8.0
Polyethylene 4.0
Candelilla Row 2.0
Carnauba Row 2.0
Planool-G (Nippon Seika) 5.0
LUSPLAN DD-DHR (Nippon Seika) 7.5
Planool-LG2 (Nippon Seika) 6.0
Planool-DP (Nippon Seika) 0.1
Planpool-LG1 (Nippon Seika) 0.1
Planpool-LG3 (Nippon Seika) 0.1
Planpool-LG4 (Nippon Seika) 0.1
Planool-S (Nippon Seika) 0.1
Squalane 5.0
Ascorbyl tetrahexyldecanoate 0.01
Hyaluronate Na 0.05
Sorbitan isostearate 0.1
Tocopherol 0.1
BHT 0.01
Methyl paraben 0.1
Titanium oxide proper amount zinc oxide proper amount red 202 proper amount iron oxide proper amount yellow 4 proper amount borosilicate (Ca / Al) proper amount silica proper amount tin oxide proper amount -------------- −−−−−−−−−−−−−−
(Preparation method)
After heating, stirring and mixing all the components uniformly, they were filled in a mold and quenched.

Example 29 Lip gloss

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Hydrogenated polyisobutene Total amount of 100 LUSPLAN DD-DA7 (Nippon Seika) 15.0
LUSPLAN SR-DM4 (Nippon Seika) 3.0
Planool-G (Nippon Seika) 0.1
Planool-SUN (Nippon Seika) 0.1
Planool-MAS (Nippon Seika) 0.1
Planool-ISS (Nippon Seika) 0.1
Planpool-LG1 (Nippon Seika) 0.1
Planpool-LG2 (Nippon Seika) 0.1
Planpool-LG3 (Nippon Seika) 0.1
Planpool-LG4 (Nippon Seika) 0.1
LUSPLAN PI-DA (Nippon Seika) 0.1
Pentaerythrityl tetraisostearate 32.0
Malate ester of Synthesis Example 1 3.0
Diphenyl dimethicone 5.0
Dimethylsilylated silica 6.0
Methyl paraben 0.1
BHT 0.01
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
All components were melted by heating and mixed uniformly.

Example 30 Water-containing gloss

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Octyldodecanol 27.0
Ethyl cellulose 2.5
Malate ester of Synthesis Example 1 5.0
Isopropyl sebacate (Nippon Seika) 3.0
LUSPLAN PI-DA (Nippon Seika) 2.0
LUSPLAN SR-DP4 (Nippon Seika) 2.0
Planool-G (Nippon Seika) 0.1
Planool-SUN (Nippon Seika) 0.1
Planool-ISS (Nippon Seika) 0.1
Planool-MAS (Nippon Seika) 0.1
Planpool-LG1 (Nippon Seika) 0.1
Planpool-LG2 (Nippon Seika) 0.1
Planpool-LG3 (Nippon Seika) 0.1
Planpool-LG4 (Nippon Seika) 0.1
Dimethylsilylated silica 0.5
Dextrin palmitate 0.1
PEG-60 hydrogenated castor oil 1.0
Red No. 202 Suitable amount Red No. 218 Suitable amount Red 223 Suitable amount Orange No. 201 Suitable amount Sorbitan stearate, coconut fatty acid sucrose mixture (ALACEL2121 manufactured by Croda Corporation) 3.0
Part B Glycerin 7.0
Neosolue-AquaS (Nippon Seika) 0.4
Maltose 2.0
Phenoxyethanol 0.2
Water Amount that totals 100--------------------------
(Preparation method)
Part A and part B were each heated and melted to make them uniform, and part A and part B were mixed.

Example 31 Tinto gloss

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Hydrogenated polyisobutene Total amount of 100 Malate ester of Synthesis Example 1 3.0
Diethylhexyl succinate (Nippon Seika) 3.0
Diisobutyl adipate (Nippon Seika) 3.0
Diisopropyl sebacate (Nippon Seika) 3.0
Red 218 0.1
Part B LUSPLAN PI-DA (Nippon Seika) 20.0
LUSPLAN DD-DA5 (Nippon Seika) 10.0
Trihexanoin (Nippon Seika) 6.0
Preservatives Appropriate amount Antioxidant Appropriate amount -----------------------------------
(Preparation method)
Part A was stirred and mixed at about 80 ° C, and then Part B heated to about 80 ° C was added with stirring, and then cooled.

Example 32 Mascara

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Iron oxide (black) 10.0
Purified water Total amount to be 100 Part B Polyacrylate emulsion 30.0
Part C Light isoparaffin 30.0
Solid paraffin 4.0
Carnauba Row 2.0
Beeswax 2.0
Malate ester of Synthesis Example 1 1.0
Planool-G (Nippon Seika) 0.5
Trimethylsiloxysilicic acid 1.5
Sorbitan sesquioleate 4.0
PEG-15 glyceryl stearate 0.8
Preservatives qs perfume qs ---------------------------------
(Preparation method)
After dispersing part A with a homomixer, part B was heated and mixed (aqueous phase). The components of Part B were mixed by heating, an aqueous phase was added to Part B, and the mixture was uniformly emulsified and dispersed with a homomixer.

Example 33 Eye shadow

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Malate ester of Synthesis Example 1 5.0
Planool-H (Nippon Seika) 0.6
Mica Total amount of 100 Talc 24.0
Siliconized titanium oxide 20.0
Siliconized iron oxide 1.9
Cyclomethicone 3.5
Trimethylsiloxysilicic acid 1.5
Octyl methoxycinnamate 1.0
Dimethicone (10cs) 0.5
Tocopherol 0.1
BHT 0.1
Phenoxyethanol 0.4
Dye appropriate amount Fragrance appropriate amount --- --- ---------------------
(Preparation method)
All components were mixed uniformly.

Example 34 Liquid Foundation

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Planpool-G (Nippon Seika) 2.0
Planool-DP (Nippon Seika) 1.0
Polyglyceryl triisostearate-2 2.0
Glyceryl stearate (SE) 1.0
Stearic acid PG (SE) 1.0
Polysorbate 80 0.2
Ethylhexyl methoxycinnamate 1.0
Malate ester of Synthesis Example 1 2.0
Tocopherol 0.1
Propyl paraben 1.0
Part B Titanium oxide / iron oxide mixture (FDP-W-007 manufactured by Toshiki Pigment Co., Ltd.) 18.0
Mica 7.0
BG 5.0
Methyl paraben 0.2
Purified water Total amount to be 100 Part C Cellulose gum (2% aqueous dispersion) 5.0
Xanthan gum (2% aqueous dispersion) 5.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
A part, B part and C part are heated and mixed. Part B was added to Part A, and after emulsification, the mixture was cooled to about 50 ° C., and Part C was added and stirred until uniform.

Example 35 Foundation

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Malate ester of Synthesis Example 1 5.0
Cyclopentasiloxane 4.0
Mineral oil 4.0
Ethylhexyl methoxycinnamate3.0
LUSPLAN DD-DHR (Nippon Seika) 1.0
Planool-H (Nippon Seika) 1.0
Planool-G (Nippon Seika) 1.0
Planool-MAS (Nippon Seika) 1.0
Vaseline 1.0
Phenyltrimethicone 2.0
Sorbitan isostearate 1.5
Tribehenin 0.5
(Butyl acrylate / glycol dimethacrylate) crosspolymer,
Silica, (methyl methacrylate / glycol dimethacrylate)
Crosspolymer mixture 2.0
Boron nitride 1.0
PEG / PPG-19 / 19 dimethicone,
Cyclopentasiloxane mixture 4.0
Disteardimonium hectorite (20%) 2.5
Polypropylsilsesquioxane,
Cyclopentasiloxane mixture 1.0
Mica 15.0
Talc 4.0
Zinc oxide 5.0
Titanium oxide 10.0
Iron oxide 1.5
Part B Water Total amount of 100 DPG 4.0
Maltitol (75% solution) 1.0
Neosolue-AquaS (Nippon Seika) 0.4
Na chloride 1.0
BG 1.0
Tremoist-SL (Nippon Seika) 1.0
Hyaluronic acid (1% solution) 0.1
Phenoxyethanol 0.3
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part A was heated to about 70 ° C., stirred well, and uniformly dispersed. Part B was heated to about 70 ° C. and made uniform, and then Part B was added to Part A, and the mixture was stirred and emulsified at about 70 ° C. and cooled to about 40 ° C.

Example 36 Sunscreen cosmetic

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Quaternium-18 hectorite 1.0
Part B Cyclomethicone 14.0
Diphenyl dimethicone 2.0
Malate ester of Synthesis Example 1 1.0
Planool-H (Nippon Seika) 1.0
Planool-G (Nippon Seika) 0.5
Planool-MAS (Nippon Seika) 2.0
Dicaprylyl carbonate 1.0
Dimethicone copolyol 5.5
Part C Silicone treated fine particle titanium oxide 3.9
Silicone treated zinc oxide 2.1
D part Stearic acid Al 0.7
Al hydroxide 0.5
Isononyl isononanoate 2.5
Isodecyl neopentanoate (Nippon Seika) 1.5
Neosolue-MP (Nippon Seika) 1.0
Neosolue-DE (Nippon Seika) 1.0
Part E Trimethylsiloxysilicic acid 1.2
Stearyl glycyrrhetinate 0.02
Sorbitan sesquioleate 2.0
Tocopherol 0.02
Part F Na chloride 1.0
Methyl paraben 0.15
Purified water Amount that totals 100 ----
(Preparation method)
Add Part A to Part B and stir. Further, C is added and dispersed using a roller mill. Part D is heated and melted and added to the mixture of parts A, B and C, and part E is further added to about 70 ° C. Part F is heated and gradually emulsified into the mixture of parts A to E while stirring. Cool with stirring, stop stirring at 40-35 ° C and leave.

Example 37 Sunscreen cosmetic

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Phytocompo-PP (Nippon Seika) 1.0
BG 10.0
Glycerin 9.0
B part octocrylene 4.0
Octyl salicylate 4.0
Hexyl diethylaminohydroxybenzoyl benzoate 2.2
t-butylmethoxydibenzoylmethane 1.0
Diethylhexyl sebacate (Nippon Seika) 3.0
Pentaerythrityl tetraethylhexanoate (Nippon Seika) 2.0
Isopropyl sebacate (Nippon Seika) 1.0
Malate ester of Synthesis Example 1 1.5
Behenyl alcohol 2.0
Cetearyl alcohol 2.0
Planool-MAS (Nippon Seika) 1.0
Tocopherol 0.05
Part C Neosolue-AquaS (Nippon Seika) 1.0
Methylparaben qs Water q D to be 100 in total D carbomer (2%) 5.0
Tremoist-SL (Nippon Seika) 10.0
Water-dispersed titanium oxide 5.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part A is uniformly dispersed. Part B and Part C are each heated and melted at about 70 ° C. Part B is gradually added to Part A, then Part C is gradually added and emulsified. Cool while stirring, add Part D at 45 ° C. and stir.

Example 38 Lipstick

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Planool-DP (Nippon Seika) 10.0
Planool-G (Nippon Seika) 1.0
Hydrogenated polyisobutene 11.0
Malate ester of Synthesis Example 1 1.0
Diisostearyl malate Total amount of 100 Tri (caprylic / capric) glyceryl (Nippon Seika) 13.0
Squalane 10.0
Isotridecyl isononanoate 8.0
Shea butter 2.0
Microcrystalline wax 12.4
Polyethylene 4.0
Candelilla Row 2.0
Carnauba Row 2.0
Sorbitan isostearate 0.2
Planool-LG2 (Nippon Seika) 6.0
Planool-DP (Nippon Seika) 0.1
Planpool-LG1 (Nippon Seika) 0.1
Planpool-LG3 (Nippon Seika) 0.1
Planpool-LG4 (Nippon Seika) 0.1
Planool-S (Nippon Seika) 0.1
Hexa (hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl
2.0
Tremoist-TP (Nippon Seika) 0.01
Ascorbyl tetrahexyldecanoate 0.01
Hyaluronate Na 0.05
Sorbitan isostearate 0.1
Tocopherol 0.1
BHT 0.01
Methyl paraben 0.1
Titanium oxide proper amount zinc oxide proper amount red 202 proper amount iron oxide proper amount yellow 4 proper amount borosilicate (Ca / Al) proper amount silica proper amount tin oxide proper amount -------------- −−−−−−−−−−−−−−
(Preparation method)
After heating, stirring and mixing all the components uniformly, they were filled in a mold and quenched.

Example 39 Lipstick

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Hydrogenated polyisobutene Total amount of 100 Diisostearyl malate 25.0
Malate ester of Synthesis Example 1 1.0
LUSPLAN DD-DHR (Nippon Seika) 3.0
LUSPLAN DD-DA7 (Nippon Seika) 1.0
LUSPLAN DD-DA5 (Nippon Seika) 1.0
LUSPLAN SR-DP4 (Nippon Seika) 0.3
LUSPLAN PI-DA (Nippon Seika) 0.1
LUSPLAN DD-IS (Nippon Seika) 0.1
Phenyltrimethicone 12.0
Alkyl benzoate (C12-15) 5.0
Caprylyl methicone 2.0
Diethylhexyl succinate (Nippon Seika) 2.0
Octyldodecanol 5.0
Diisopropyl dilinoleate 2.0
Planool-MAS (Nippon Seika) 3.0
Pentaerythrityl tetraisostearate 1.0
Pentaerythrityl tetraethylhexanoate (Nippon Seika) 1.0
Polyglyceryl isostearate-2 0.5
Isohexadecane 0.5
Ethylhexyl palmitate 1.0
Paraffin 5.0
Microcrystalline wax 0.5
Polyethylene 0.5
Candelilla Row 1.0
Carnauba Row 0.5
Hexa (hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl
1.0
Tremoist-TP (Nippon Seika) 0.01
Hyaluronate Na 0.05
Tocopherol 0.1
BHT 0.01
Methyl paraben 0.1
Titanium oxide proper amount zinc oxide proper amount red 202 proper amount iron oxide proper amount yellow 4 proper amount borosilicate (Ca / Al) proper amount silica proper amount tin oxide proper amount -------------- −−−−−−−−−−−−−−
(Preparation method)
After heating, stirring and mixing all the components uniformly, they were filled in a mold and quenched.

Example 40 Multi Painter

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Dimethylsilylated silica 4.0
Triethylhexanoin (Nippon Seika) 10.0
Triisostearin 3.0
LUSPLAN PI-DA (Nippon Seika) Total amount of 100 Dipropylene glycol 1.1
Tetradecene 0.5
Dimethicone 1.0
Part B Malic ester of Synthesis Example 1 3.0
Silica 10.0
Hydrogenated polyisobutene 4.0
LUSPLAN DD-DA7 (Nippon Seika) 1.0
LUSPLAN SR-DM4 (Nippon Seika) 1.0
Dextrin palmitate 2.0
(Palmitic acid / ethylhexanoic acid) dextrin 1.0
Inulin stearate 0.5
Dextrin myristate 1.0
Polyglyceryl triisostearate-2 4.0
Glyceryl diisostearate1.0
Planpool-LG2 (Nippon Seika) 0.1
Planpool-LG4 (Nippon Seika) 0.1
Diphenyl dimethicone 5.0
Titanium oxide Appropriate quantity Zinc oxide Appropriate quantity Red 202 Appropriate quantity Red 201 Appropriate quantity Iron oxide Appropriate quantity Yellow 4 Appropriate quantity Blue 1 Appropriate amount Borosilicate (Ca / Al) Appropriate amount Tin oxide Appropriate amount Mica Appropriate amount Silicic acid (Na / K / Al) Appropriate amount Tocopherol Appropriate amount C part Sulfuric acid Ba 10.0
Methyl methacrylate crosspolymer 1.0
(Vinyl dimethicone / methicone silsesquioxane) crosspolymer
1.0
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
Part A is dispersed with a homomixer, and part B is heated and melted and dispersed using a roller mill. A part, B part and C part are uniformly mixed.

Example 41 Night Trip

Component Content (% by weight)
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
Part A Diisostearyl malate Total amount of 100 Triethylhexanoin (Nippon Seika) 10.0
Ceramide 2 0.01
Ceramide 3 0.01
Ceramide 5 0.01
Ceramide 6 0.01
Cholesterol 0.2
Phytosterol 0.2
Polyamide-3 5.0
Sucrose tetrastearate triacetate 5.0
Methylparaben qs BHT qs Part B Malate ester of Synthesis Example 1 10.0
Hydrogenated polyisobutene 15.0
Squalane 10.0
Planool-G (Nippon Seika) 10.0
Planool-MAS (Nippon Seika) 5.0
Microcrystalline wax 5.0
Polyethylene wax 3.0
Ceresin 0.5
−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−−
(Preparation method)
After uniformly mixing Part A, the mixture is heated and melted at 95 ° C. Add part B, dissolve uniformly, and allow to cool.

In the above formulation, details of the components described by the product name are as follows.
@ Plandol-H: dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl)
@ Plandol-S: dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl)
@ Plandiol-G: dimer dilinoleyl bis dimer dilinoleate (behenyl / isostearyl / phytosteryl)
〇Plandiol-DP: bisdiglyceryl polyacyl adipate-2
{Plandol-ISS: phytosteryl isostearate} Planool-SUN: sunflower seed oil fatty acid phytosteryl〇 Planool-MAS: macadamia nut oil fatty acid phytosteryl
@ Plandiol-LG2: dilauroylglutamate (phytosteryl / octyldodecyl)
@ Plandiol-LG3: di (phytosteryl / octyldodecyl / behenyl) lauroylglutamate
@ Plandol-LG4: di (phytosteryl / octyldodecyl / behenyl) lauroylglutamate
〇LUSPLAN DD-IS: dimer dilinoleyl diisostearate〇LUSPLAN PI-DA: di (distearyl / phytosteryl) dimer dilinoleate
〇LUSPLAN DD-DHR: Dimer linoleyl hydrogenated rosin condensate 〇LUSPLAN DD-DA5: Dimer linoleic acid dimer linoleil 〇LUSPLAN DD-DA7: Dimer linoleic acid dimer linoleyl 〇LUSPLAN SR-DM4: Die Dimer linoleyl merlinoleate, glyceryl tri (caprylic / capric acid) @LUSPLAN SR-DP4: dimerinoleyl dimer linoleate, pentaerythrityl tetraisostearate @ Neosolue-Aqulio: bisethoxydiglycol cyclohexanedicarboxylate {Neosolue-Aqua: (eicosanediacid / tetradecandioic acid) polyglyceryl-10, glycerin} Neosolue-AquaS: (eicosanediacid / Toradekan diacid) polyglyceryl-10, glycerin 〇_Neosolue-MP: Jineopentan methyl pentanediol 〇_Neosolue-DE: Jineopentan diethyl pentanediol 〇_Neosolue-DISM: diisostearyl malate (methyl branched)
〇Phytocompo-PP: hydrogenated lecithin, phytosterols〇 Phytocompo-C: hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3, ceramide 6II
〇Phytopresome Cera23: hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3
〇 Phytopresome MEL: glycolipid, hydrogenated lecithin, BG, purified water カ ラ Elcalactone MCT: γ-docosalactone, tri (caprylic / capric acid) glyceryl 〇 Elcalactone DES: γ-docosalactone, diethyl sebacate 〇 Tremoist- TP: White jellyfish polysaccharide @ Tremoist-SL: White jellyfish polysaccharide aqueous solution (1%)

Polarized light microscope image of malic ester of Synthesis Example 1

Claims (2)

A cosmetic containing a malic ester represented by the following general formula (1).
(In the formula, R represents a linear aliphatic alcohol residue having 14 to 28 carbon atoms.)   The cosmetic according to claim 1, wherein R in the general formula (1) is a linear aliphatic alcohol residue having 16 to 22 carbon atoms.