CN1103781C - 丰富的细胞外产物和其生产与使用方法 - Google Patents

丰富的细胞外产物和其生产与使用方法 Download PDF

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Publication number
CN1103781C
CN1103781C CN94194859A CN94194859A CN1103781C CN 1103781 C CN1103781 C CN 1103781C CN 94194859 A CN94194859 A CN 94194859A CN 94194859 A CN94194859 A CN 94194859A CN 1103781 C CN1103781 C CN 1103781C
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China
Prior art keywords
protein
combination vaccine
mycobacterium tuberculosis
terminal
immunized
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Expired - Fee Related
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CN94194859A
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English (en)
Chinese (zh)
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CN1142231A (zh
Inventor
M.A.霍维茨
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University of California Berkeley
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University of California Berkeley
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Priority claimed from US08/156,358 external-priority patent/US6752993B1/en
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Publication of CN1142231A publication Critical patent/CN1142231A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Multi-Process Working Machines And Systems (AREA)
  • Telephone Function (AREA)
  • Stringed Musical Instruments (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN94194859A 1993-11-23 1994-11-18 丰富的细胞外产物和其生产与使用方法 Expired - Fee Related CN1103781C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/156,358 US6752993B1 (en) 1993-11-23 1993-11-23 Abundant extracellular product vaccines and methods for their production and use
US08/156,358 1993-11-23
US28966794A 1994-08-12 1994-08-12
US08/289,667 1994-08-12

Publications (2)

Publication Number Publication Date
CN1142231A CN1142231A (zh) 1997-02-05
CN1103781C true CN1103781C (zh) 2003-03-26

Family

ID=26853097

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94194859A Expired - Fee Related CN1103781C (zh) 1993-11-23 1994-11-18 丰富的细胞外产物和其生产与使用方法

Country Status (12)

Country Link
US (1) US6761894B1 (OSRAM)
EP (1) EP0771322B9 (OSRAM)
JP (2) JPH09505588A (OSRAM)
CN (1) CN1103781C (OSRAM)
AT (1) ATE407945T1 (OSRAM)
AU (1) AU1097795A (OSRAM)
BR (1) BR9408135A (OSRAM)
CA (1) CA2177249C (OSRAM)
DE (1) DE69435138D1 (OSRAM)
DK (1) DK0771322T3 (OSRAM)
ES (1) ES2313719T3 (OSRAM)
WO (1) WO1995014713A2 (OSRAM)

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US7300660B2 (en) 1993-11-23 2007-11-27 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
US6752993B1 (en) 1993-11-23 2004-06-22 The Regents Of The University Of California Abundant extracellular product vaccines and methods for their production and use
DK0771322T3 (da) 1993-11-23 2008-11-24 Univ California Rigeligt forekommende, ekstracellulære produkter og fremgangsmåder til fremstilling samt anvendelse deraf
DE69529219T2 (de) * 1994-07-01 2003-11-06 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Helicobacter proteine und impstoffe
WO1996005223A1 (en) * 1994-08-12 1996-02-22 The Regents Of The University Of California Abundant extracellular products and methods for their production and use
JPH11506320A (ja) * 1995-05-23 1999-06-08 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 豊富な細胞外産物、ならびにそれらを産生および使用するための方法
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6338852B1 (en) 1995-09-01 2002-01-15 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
AU1463097A (en) * 1996-01-04 1997-08-01 Rican Limited Helicobacter pylori bacterioferritin
JP2001500004A (ja) * 1996-07-26 2001-01-09 アンスティテュ、パストゥール ヒト型結核菌（ｍｙｃｏｂａｃｔｅｒｉｕｍ ｔｕｂｅｒｃｕｌｏｓｉｓ）のデサチュレーション抗原
US6284255B1 (en) * 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US6013660A (en) * 1996-10-02 2000-01-11 The Regents Of The University Of California Externally targeted prophylactic and chemotherapeutic method and agents
DE69838948T2 (de) * 1997-01-21 2008-10-02 The Regents Of The University Of California, Oakland Epitopen eines extrazellulären antigens
US6350456B1 (en) * 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6544522B1 (en) 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US5968524A (en) * 1997-12-23 1999-10-19 Genesis Research & Development Corp. Methods and compounds for the treatment of immunologically-mediated psoriasis
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
CN101090974B (zh) 2004-11-16 2011-05-11 克鲁塞尔荷兰公司 包含重组病毒载体的多价疫苗
CN102850445B (zh) * 2012-09-24 2014-01-08 张银辉 一组结核分枝杆菌菌体特异性抗原及其纯化方法

Citations (2)

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WO1992014823A1 (en) * 1991-02-14 1992-09-03 N.V. Innogenetics S.A. Mycobacterium polypeptides and nucleic acids encoding them for diagnosis and control of tuberculosis

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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004272A1 (en) * 1989-09-19 1991-04-04 N.V. Innogenetics S.A. Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
WO1992014823A1 (en) * 1991-02-14 1992-09-03 N.V. Innogenetics S.A. Mycobacterium polypeptides and nucleic acids encoding them for diagnosis and control of tuberculosis

Also Published As

Publication number Publication date
BR9408135A (pt) 1997-08-05
JPH09505588A (ja) 1997-06-03
EP0771322A1 (en) 1997-05-07
JP2005104983A (ja) 2005-04-21
ES2313719T3 (es) 2009-03-01
US6761894B1 (en) 2004-07-13
EP0771322B1 (en) 2008-09-10
ATE407945T1 (de) 2008-09-15
AU1097795A (en) 1995-06-13
CA2177249C (en) 2010-10-19
DE69435138D1 (de) 2008-10-23
CA2177249A1 (en) 1995-06-01
CN1142231A (zh) 1997-02-05
JP4537178B2 (ja) 2010-09-01
WO1995014713A3 (en) 1995-12-28
EP0771322B9 (en) 2009-08-12
DK0771322T3 (da) 2008-11-24
WO1995014713A2 (en) 1995-06-01

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