CN110339115B - Repair essence and preparation method thereof - Google Patents

Abstract

The invention discloses a repair essence and a preparation method thereof, aiming at providing an essence which can effectively improve skin permeability, balance water storage, improve skin barrier function, relieve and resist inflammation, and the technical key points of the essence comprise components such as glycerin or butanediol, erythritol or trehalose, sodium hyaluronate, natural plant repair factors, tetrahydro-methyl pyrimidine carboxylic acid, water// butanediol// amino acid complex, water// lactobacillus/soybean fermentation product extract// butanediol and the like; belongs to the technical field of cosmetics.

Description

Repair essence and preparation method thereof

Technical Field

The invention provides essence and a preparation method thereof; in particular to a repairing essence, belonging to the technical field of cosmetics.

Background

Along with the acceleration of work and life rhythm of people, various pressures are increasingly greater, and in addition, the people are suffered from the disabilities of multiple external factors such as air pollution, screen radiation, ultraviolet rays and the like to the skin all the year round, more and more people can be troubled by the problems of dry, rough, dark, fine lines and the like of the skin, and along with the gradual improvement of the consciousness of people on skin protection and repair, the demand on repair cosmetics is also continuously expanded.

At present, repair products on the market are various, the skin repair effect is unsatisfactory, and some products have safety problems, for example, stimulation components such as preservatives and bactericides are added into the products, so that the skin is gradually rough and allergic after long-term use, and the skin barrier of a human body is damaged. Therefore, it is necessary to develop a cosmetic which is safe, non-irritating, non-toxic and side-effect-free, and has a remarkable repairing effect.

Disclosure of Invention

In view of the above disadvantages, the first objective of the present invention is to provide a repair essence which can effectively improve skin penetration, balance water storage, improve skin barrier function, relieve inflammation, and is safe and non-irritant.

The second technical scheme provided by the invention is a preparation method of the repair essence.

Therefore, the first technical scheme provided by the application is as follows:

the repairing essence consists of raw material components of an A phase, a B phase, a C phase, a D phase, an E phase and an F phase, and the mass percentage of each phase component is as follows according to the total mass of 100%:

phase A: adding water to 100%, 1-15% of glycerol or butanediol, 1-10% of 1, 3-propylene glycol or dipropylene glycol, 1-10% of erythritol or trehalose, 1-10% of glycerol// glycerol acrylate/acrylic acid copolymer// propylene glycol// water, 0.01-0.2% of EDTA disodium, 0.01-0.2% of sodium hyaluronate and 0.01-0.2% of hydrolyzed sodium hyaluronate;

phase B: carbomer sodium or polyacrylate crosslinked copolymer-60.01-0.2%, carbomer or ammonium acryloyldimethyl taurate/behenyl alcohol polyether-25 methacrylate crosslinked polymer 0.01-0.2%;

and C phase: 1.3-propylene glycol or dipropylene glycol 1-10%, p-hydroxyacetophenone 0.1-1%, 1, 2-hexanediol 0.05-1%;

phase D: 101-10% of glycerol polyether-26 or methyl glucitol polyether-101%, 1-10% of water// hydroxyethyl urea, 0.1-5% of natural plant repair factor, 0.5-10% of tetrahydro-methylpyrimidine carboxylic acid, 0.5-6% of water// butanediol// amino acid complex, and 0.01-1% of water// butanediol// water temple laver polysaccharide;

phase E: water// propylene glycol// Botrytis hirsutus extract 0.01-1%, water// Lactobacillus/Soybean fermentation product extract// butanediol 0.001-0.1%, fructo-oligosaccharide// glucose// fructose// sucrose 0.002-0.08%, Rice fermentation product filtrate 0.002-0.08%, Saccharomyces bifidus fermentation product lysate 0.01-0.1%, inulin// water// alpha-glucan oligosaccharide 0.01-0.1%, carnosine 0.001-0.1%, water 0.001-0.1%;

and (3) phase F: 0.01-0.5% of PEG-40 hydrogenated castor oil and 0.001-0.1% of essence.

Further, the water in the essence A phase is electrolytic reductive anion water.

Further, the natural plant repairing factor in the phase D of the essence comprises butylene glycol, water, an extract of centella asiatica, an extract of polygonum cuspidatum root, an extract of scutellaria baicalensis root, an extract of tea, an extract of glycyrrhiza glabra root, an extract of chamomile flower and an extract of rosemary leaf, wherein the butylene glycol content is 50%, the water content is 38%, the centella asiatica extract content is 5%, the polygonum cuspidatum root extract content is 2%, the scutellaria baicalensis root extract content is 2%, the tea extract content is 1%, the glycyrrhiza glabra root extract content is 1%, the chamomile flower extract content is 0.5% and the rosemary leaf extract content is 0.5% by total weight.

Further, the water// butanediol// amino acid compound in the essence D phase is a mixture of a plurality of raw materials, and the water content is 67.5-69.1%, the butanediol content is 30% and the amino acid compound content is 0.9-2.5% based on the total weight of the essence D phase.

Furthermore, the amino acid compound comprises, by weight, 4.2% of lysine, 4.2% of histidine, 1.5% of histidine, 3.8% of arginine, 8.1% of aspartic acid, 3.1% of threonine, 13.9% of serine, 12.9% of glutamic acid, 3.1% of proline, 25.1% of glycine, 4.5% of alanine, 3.1% of valine, 2.8% of isoleucine, 7.1% of leucine, 3.5% of tyrosine and 3.3% of phenylalanine.

Further, the water/hydroxyethyl urea in the essence D phase is a mixture of a plurality of raw materials, wherein the mass ratio of the water to the hydroxyethyl urea is 8:9-9: 8; the water// butanediol// water temple laver polysaccharide in the phase D is a mixture of multiple raw materials, and according to the total weight, the water content is 69.5%, the butanediol content is 30%, and the water temple laver polysaccharide content is 0.5%.

Further, the water// propylene glycol// Larix tenerricellii extract in the essence E phase is a mixture of various raw materials, and the water content is 48-52%, the propylene glycol content is 48-52%, the Larix tenerricellii extract content is 1-2.5%, and the sum of the weight of each component is 100%; the water// lactobacillus/soybean fermentation product extract// butanediol described in phase E is a mixture of various raw materials, wherein the mass ratio of water, lactobacillus/soybean fermentation product extract and butanediol is 78:10: 10.

Furthermore, the fructo-oligosaccharide// glucose// fructose// sucrose in the essence E phase is a mixture of various raw materials, and according to the total weight, the fructo-oligosaccharide content is 93%, the glucose content is 3%, the fructose content is 2%, and the sucrose content is 2%; the inulin// water// alpha-glucan oligosaccharide in phase E is a mixture of various raw materials, and the inulin content is 60-80%, the water content is 25%, the alpha-glucan oligosaccharide content is 1-14%, and the sum of the weight of the components is 100%, based on the total weight of the raw materials.

The second technical scheme provided by the invention is that the preparation method of the repair essence mainly comprises the following steps:

1) heating the C-phase material to 70 ℃, and stirring and dissolving completely for later use;

2) uniformly stirring the F-phase material at normal temperature for later use;

3) adding the phase A materials into an emulsifying pot, heating to 90 ℃, and stirring to dissolve completely;

4) adding the phase B material into the solution obtained in the step 3), homogenizing for 7min, dispersing uniformly, and cooling;

5) cooling the solution obtained in the step 4) to 45 ℃, respectively adding the pretreated C, D, E, F-phase materials, stirring for 15min, and uniformly mixing.

Compared with the prior art, the invention has the following beneficial effects:

1. in the technical scheme provided by the invention, the tetrahydro-methyl pyrimidine carboxylic acid is a strong water structure forming substance, can structure free water in cells, increases the number of surrounding water molecules, enhances the interaction between the water molecules, and restrains the surrounding water molecules to form a complex; the electrolytic reducing anion water is also called as small molecule water, the surface tension of the electrolytic reducing anion water is lower than that of water (under the environment of 25 ℃, the surface tension of the water is 72dyn/cm, the surface tension of the electrolytic reducing anion water is 56dyn/cm), the osmosis is stronger than that of the water, the deep osmosis moisturizing effect can be achieved, and according to the principle of an electric double layer, the electrolytic reducing anion water can ionize grease (dirt) and the surface of skin positively, the grease and the skin generate mutual repulsion action, so that the grease (dirt) is stripped, the small molecule water can also neutralize free radicals caused by factors such as ultraviolet rays, aging and the like, the tetrahydro methyl pyrimidine carboxylic acid and the electrolytic reducing anion water are mutually compatible and are wrapped around cells, enzymes, proteins and other organic molecules to form a protective shell with the functions of protecting, nourishing and stabilizing hydration, so as to achieve the functions of moisturizing, water locking and reducing water loss, and can avoid the damage of external pressure factors (such as UV radiation, blue light, dehydration, stimulation and the like) to the skin, inhibit the invasion of microorganisms and allergens, inhibit inflammatory stress signals, stabilize proteins and protect the proteins from being decomposed, thereby stabilizing cell membranes, protecting normal growth and metabolism of cells, and playing the effects of resisting aging and firming, shining the skin and repairing skin barriers.

2. The natural plant repair factor provided by the invention is compounded by the plant active ingredients in 7, has no cytotoxicity, has stronger anti-inflammatory and relieving effects, and strengthens the skin barrier through immune regulation and relieving; the amino acid complex is similar to skin stratum corneum components, has small molecular weight, can easily penetrate into deep skin, keep skin moisture, provide skin cell nutrition, proliferate skin fibroblast and prevent skin aging; the polysaccharide of the porphyra mosque can form a nano-scale film on the surface of the skin to protect the skin from external stimulation. The active ingredients are combined with the tetrahydro-methyl pyrimidine carboxylic acid, and the active ingredients are wrapped around cells and permeate into skin cuticle, so that the moisture of the skin can be locked, the skin is prevented from being dry and rough, the skin is moist and smooth, the young health state is maintained, the skin defense force is enhanced, the skin is protected against external environment injury, and the skin barrier function is enhanced.

3. The invention contains prebiotics (inulin, alpha-glucan oligosaccharide, fructo-oligosaccharide, yeast fermentation lysate, rice fermentation product filtrate and the like) and probiotic (lactobacillus and the like) fermentation products, promotes the growth of probiotics on the surface of the skin, inhibits harmful bacteria, balances the skin micro-ecological system, nourishes the skin, repairs skin injury and enables the skin to be healthy and tough through a micro-ecological health technology. The active ingredients such as tetrahydromethylpyrimidine carboxylic acid, small molecular water, a pinocembrus tomentosa extract, Aphanothece purpurea polysaccharide and the like are cooperated, so that sufficient nutrients are provided for the skin, the skin is kept and moistened continuously, the dry and water-deficient skin is effectively improved, and the effect of deeply moisturizing and repairing the skin is achieved; meanwhile, the skin barrier function is maintained, and the inflammation and bacteria are reduced.

4. The repair essence disclosed by the invention does not contain substances such as preservatives, animal fat, fluorescent agent, alcohol and the like, is free from any stimulation, realizes 0 antiseptic additive component, and is safe and effective as well as free from any toxic and side effects.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is noted that, unless otherwise indicated, the various components used in the present invention are all materials known in the art, and are either commercially available or prepared by known methods.

The repair essence provided by the invention can be prepared from the following examples in the table 1. Wherein, the content of the raw materials in each example is expressed by wt%.

Table 1 examples of repair essences provided by the present invention

The preparation method of the repair essence in the embodiments 1 to 5 is as follows:

1) heating the C-phase material to 70 ℃, and stirring and dissolving completely for later use;

2) uniformly stirring the F-phase material at normal temperature for later use;

3) adding the phase A materials into an emulsifying pot, heating to 90 ℃, and stirring to dissolve completely;

4) adding the phase B material into the solution obtained in the step 3), homogenizing for 7min, dispersing uniformly, and cooling;

5) cooling the solution obtained in the step 4) to 45 ℃, respectively adding the pretreated C, D, E, F-phase materials, stirring for 15min, and uniformly mixing.

In addition, aiming at the invention points of the application, the invention also provides comparative examples 1-5 in the table 2, and the specific components and contents of the repair essence in the comparative examples are shown in the table 2 below.

Table 2 comparative examples provided by the invention

Wherein, compared with the embodiment 3, the tetrahydro-methyl pyrimidine carboxylic acid in the D phase is replaced by the same amount of the natural plant repair factor, namely the content of the natural plant repair factor is 4.5 percent in the comparative example 1; comparative example 2 compared to example 3, the natural plant repair factor in phase D was replaced with an equal amount of water// butanediol// amino acid complex, i.e. the water// butanediol// amino acid complex content was 2.5%; comparative example 3 compared to example 3, water// lactobacillus/soy fermentation product extract// butylene glycol in phase E was replaced with an equal amount of water// butylene glycol// water mosque laver polysaccharide, i.e. water// butylene glycol// water mosque laver polysaccharide content was 0.61%; comparative example 4 in comparison with example 3, the amount of deionized water used for both the filtrate of the rice fermentation product in the D phase and the amount of fructo-oligosaccharide// glucose// fructose// sucrose in the E phase were replaced with the same amounts; comparative example 5 compares with example 3, and the small molecule water in phase A is replaced by deionized water.

The natural plant restoration factors described in the above examples and comparative examples are composed of butylene glycol, water, an extract of centella asiatica, an extract of polygonum cuspidatum root, an extract of scutellaria baicalensis root, an extract of tea leaves, an extract of glycyrrhiza glabra root, an extract of chamomile flower, and an extract of rosemary leaf, and based on the total weight, the content of butylene glycol is 50%, the content of water is 38%, the content of centella asiatica is 5%, the content of polygonum cuspidatum root is 2%, the content of scutellaria baicalensis root is 2%, the content of tea leaves is 1%, the content of glycyrrhiza glabra root is 1%, the content of chamomile flower is 0.5%, and the content of rosemary leaf is 0.5%.

Further, the water// butanediol// amino acid compound in the essence D phase is a mixture of a plurality of raw materials, and the water content is 67.5-69.1%, the butanediol content is 30% and the amino acid compound content is 0.9-2.5% based on the total weight of the essence D phase.

The amino acid compound comprises, by weight, 4.2% of lysine, 1.5% of histidine, 3.8% of arginine, 8.1% of aspartic acid, 3.1% of threonine, 13.9% of serine, 12.9% of glutamic acid, 3.1% of proline, 25.1% of glycine, 4.5% of alanine, 3.1% of valine, 2.8% of isoleucine, 7.1% of leucine, 3.5% of tyrosine and 3.3% of phenylalanine.

The water/hydroxyethyl urea is a mixture of a plurality of raw materials, wherein the mass ratio of water to hydroxyethyl urea is 8:9-9: 8; the water// butanediol// water temple laver polysaccharide is a mixture of multiple raw materials, and according to the total weight, the water content is 69.5%, the butanediol content is 30%, and the water temple laver polysaccharide content is 0.5%.

The water// propylene glycol// Lapalustris extract is a mixture of multiple raw materials, and comprises 48-52% of water, 48-52% of propylene glycol and 1-2.5% of Lapalustris extract by total weight; the water// lactobacillus/soybean fermentation product extract// butanediol described in phase E is a mixture of various raw materials, wherein the mass ratio of water, lactobacillus/soybean fermentation product extract and butanediol is 78:10: 10.

The preparation method of the repair essence in comparative examples 1 to 5 was the same as that of the repair essence in examples 1 to 5.

In order to better prove the technical scheme provided by the application, the following test tests of the technical scheme provided by the application are given:

1. skin irritation test

1) Test samples: the repair essence prepared in the embodiments 1-5 of the invention.

2) The test method comprises the following steps: 25 female volunteers were selected and randomized into 5 groups (5 per group), subject met the volunteer enrollment criteria, had no history of allergic dermatitis, and had not been administered irritant products in the previous month.

About 0.020-0.025 mL of the repair essence prepared in example 1-5 was applied to a small chamber of a spot tester (Beijing science popularization Instrument factory), a special adhesive tape for external application was applied to the back of the subject, the spot tester was removed after 24 hours, and if the remaining product was wiped off with a moist paper towel, the results were recorded according to the skin reaction grading standard in the technical safety standards for cosmetics (2015) at 0.5 hour, 24 hours and 48 hours, respectively. The identification criteria are shown in Table 3.

TABLE 3 identification standards

Grade	Identification criteria
		0	Has no irritation and erythema
1	Mild erythema
		2	Erythema
3	Erythema, pimples, blisters
		4	Severe edema and bulla

As can be seen from the results of the closed patch test, the repair essence prepared in examples 1 to 5 did not show any adverse reaction and did not show the symptoms of erythema, burning sensation, pruritus and the like in 25 subjects at 0.5 hour, 24 hours and 48 hours. The repair essence is safe and has no stimulation to skin.

2. Skin moisture test

The test method comprises the following steps: selecting 50 volunteers of 20-45 years old as trial objects, randomly dividing the 50 volunteers into 10 groups (5 in each group), and enabling the skin of the test subjects to be healthy and accord with the selection standard. Each subject was uniformly applied the repair essence of examples 1 to 5 and comparative examples 1 to 5 on the face after cleansing in the morning, the moisture content of the skin before application of the cosmetics and after application of 1 hour and 8 hours was measured using a skin moisture meter CM825, respectively, the forehead part of the subject was selected as a test area, and repeated 5 times, respectively, to obtain an average value, and the increase rate of the moisture content of the skin was calculated. During the experiment, the subject was not able to apply any other cosmetic product at the experimental site.

The skin moisture content increase rate calculation formula is as follows:

skin moisture content increase rate%_t-MMV₀)/MMV₀×100％；

MMV₀: skin moisture content prior to use;

MMV_t: skin moisture content after t hours of use.

The skin moisture content increase rate measurement results are shown in Table 4.

Table 4 skin moisture test results

From the experimental results in table 4, it can be seen that the skin moisture content increase rate can reach more than 46% after 1 hour by using the repair essence prepared by the invention, and the skin moisture content increase rate can be maintained at more than 39% after 8 hours, which indicates that the repair essence has better moisturizing effect on skin and can achieve long-acting water-locking and moisturizing effects, while the skin moisture content increase rate is smaller and the moisturizing effect is poorer in the comparative example, which indicates that each component in the repair essence provided by the invention has synergistic effect, has good moisturizing effect, enables skin to be moisturized and smooth, and achieves the effects of lasting moisturizing and moistening.

3. Skin barrier function test

The skin moisture loss TEWL is an important parameter for evaluating the function of a skin moisture protective layer and can be used for evaluating the strength of the skin barrier function. The better the skin protection layer, the higher the moisture content and the lower the value of the skin moisture loss TEWL, which has the unit: g/hm²。

The test method comprises the following steps: selecting 50 volunteers of 20-45 years old as trial objects, randomly dividing the 50 volunteers into 10 groups (5 in each group), and enabling the skin of the test subjects to be healthy and accord with the selection standard. Each subject was uniformly applied the repair essence of examples 1 to 5 and comparative examples 1 to 5 on the face after cleansing in the morning, the TEWL values before application of the cosmetics and after application of 1 hour and 8 hours were respectively measured using a Tewameter TM300, the forehead region of the subject was selected as the test area, and the variation rate of the TEWL value was calculated. The change rate (%) (water loss after use-initial water loss)/initial water loss, and the average change rate (%) (sum of change rates of TEWL values per group/number of persons in the group, the smaller this value, the smaller the water loss, the stronger the skin barrier function of the test sample. During the experiment, the subject was not able to apply any other cosmetic product at the experimental site. The results of the skin TEWL measurements are shown in Table 5.

Table 5 skin barrier function test results

The experimental results in table 5 show that the repair essence of the examples has a good skin barrier function, the mean change rate of the skin TEWL value after 1 hour is more than 30%, and the mean change rate of the skin TEWL value after 8 hours is more than 25%, while the change rate of the skin TEWL value is smaller when the comparative repair essence is used, which indicates that the repair essence prepared by the invention can enhance the skin barrier function and resist the damage of the external environment to the skin.

4. Antiallergic efficacy test

The test principle is as follows: when the allergen invades the organism for the first time, the organism generates antibody IgE, and when the allergen invades the organism again, the antibody is combined with IgE on the surface of a sensitized cell and FceRI crosslinking occurs, so that an activation signal is started, signal conduction is triggered, and various enzymes including intracellular hyaluronidase are activated, and the process is called as anaphylactic reaction. Therefore, the anti-allergy activity can be judged by the hyaluronidase activity inhibition rate, and the higher the hyaluronidase activity inhibition rate is, the stronger the anti-allergy effect of the component is reflected, and the weaker the anti-allergy effect is, on the contrary, the component is.

The test method comprises the following steps: 0.1mL of 0.2 was added to the tube5mmo1/LCaC1₂Incubating the solution and 0.5mL of hyaluronidase solution (500U/mL) at 37 ℃ for 20min, adding 0.5mL of the repair essence of examples 1, 3 and 5 and comparative examples 1, 3 and 5, respectively, and incubating at 37 ℃ for 20 min; adding 0.5mL of sodium hyaluronate solution, and keeping the temperature at 37 ℃ for 30 min; then standing for 5min at normal temperature, adding 0.1mL of 0.4mo1/LNaOH solution and 0.5mL of phthalein acetone solution, heating in a boiling water bath for reaction for 15min, and immediately carrying out ice bath for 5 min; then adding 1.0mL of Ellisib reagent, diluting with 3.0mL of absolute ethanol, standing for 20min, developing, measuring the absorbance value at 530nm with a spectrophotometer, and substituting into the following formula to calculate the inhibition rate. The results are shown in Table 6.

Hyaluronidase inhibition (%) - (A-B) - (C-D) ]/(A-B) × 100%

In the formula:

a-absorbance value of control solution (sample solution replaced by acetic acid buffer solution)

B-blank control solution absorbance value (sample solution and enzyme solution were replaced by acetic acid buffer solution)

C-absorbance value of test sample solution

D-absorbance of sample blank solution (replacing enzyme solution with acetic acid buffer solution)

Evaluation criteria: in order to facilitate the evaluation of the anti-allergic activity of the sample, the anti-allergic effect is classified into the following 4 grades according to international standards: the inhibition rate is more than or equal to 70 percent, and the strong antiallergic effect is achieved; the inhibition rate is more than or equal to 50 percent, and the medium antiallergic effect is achieved; the inhibition rate is more than or equal to 30 percent and less than 50 percent, and the weak antiallergic effect is achieved; an inhibition rate of less than 30% is no antiallergic effect.

TABLE 6 anti-allergic efficacy test results

Sample (I)

Example 1

Example 3

Example 5

Comparative example 1

Comparative example 3

Comparative example 5

Inhibition ratio (%)

72.30％

75.48％

80.12％

47.81％

43.57％

58.66％

From the experimental results in table 6, it can be seen that the repair essence in the examples can significantly inhibit the activity of hyaluronidase, the inhibition rates are all greater than 70%, indicating that the repair essence has strong antiallergic effect, while the comparative examples show weak antiallergic effect, indicating that the repair essence of the invention has soothing and antiallergic effects.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims (5)

1. The repairing essence is characterized by comprising raw material components of an A phase, a B phase, a C phase, a D phase, an E phase and an F phase, wherein the mass percentages of the components of the phases are as follows according to 100 percent of the total mass:

phase A: adding electrolytic reducing anion water to 100%, 1-15% of glycerol or butanediol, 1-10% of 1, 3-propylene glycol or dipropylene glycol, 1-10% of erythritol or trehalose, 1-10% of glycerol// glycerol acrylate/acrylic acid copolymer// propylene glycol// water, 0.01-0.2% of EDTA disodium, 0.01-0.2% of sodium hyaluronate and 0.01-0.2% of hydrolyzed sodium hyaluronate;

phase B: carbomer sodium or polyacrylate crosslinked copolymer-60.01-0.2%, carbomer or ammonium acryloyldimethyl taurate/behenyl alcohol polyether-25 methacrylate crosslinked polymer 0.01-0.2%;

and C phase: 1 to 10 percent of 1, 3-propylene glycol or dipropylene glycol, 0.1 to 1 percent of p-hydroxyacetophenone and 0.05 to 1 percent of 1, 2-hexanediol;

phase D: 101-10% of glycerol polyether-26 or methyl glucitol polyether-101%, 1-10% of water// hydroxyethyl urea, 0.1-5% of natural plant repair factor, 0.5-10% of tetrahydro-methylpyrimidine carboxylic acid, 0.5-6% of water// butanediol// amino acid complex, and 0.01-1% of water// butanediol// water temple laver polysaccharide;

the natural plant repair factor in the phase D consists of butanediol, water, a centella asiatica extract, a polygonum cuspidatum root extract, a scutellaria baicalensis root extract, a tea leaf extract, a glycyrrhiza glabra root extract, a matricaria chamomilla flower extract and a rosemary leaf extract, wherein the butanediol content is 50%, the water content is 38%, the centella asiatica extract content is 5%, the polygonum cuspidatum root extract content is 2%, the scutellaria baicalensis root extract content is 2%, the tea leaf extract content is 1%, the glycyrrhiza glabra root extract content is 1%, the matricaria chamomilla flower extract content is 0.5% and the rosemary leaf extract content is 0.5%, based on 100% of the total weight of the natural plant repair factor;

the water// butanediol// amino acid compound in the D phase is a mixture of a plurality of raw materials, and the water content is 67.5-69.1%, the butanediol content is 30% and the amino acid compound content is 0.9-2.5% by weight;

phase E: water// propylene glycol// Botrytis hirsutus extract 0.01-1%, water// Lactobacillus/Soybean fermentation product extract// butanediol 0.001-0.1%, fructo-oligosaccharide// glucose// fructose// sucrose 0.002-0.08%, Rice fermentation product filtrate 0.002-0.08%, Saccharomyces bifidus fermentation product lysate 0.01-0.1%, inulin// water// alpha-glucan oligosaccharide 0.01-0.1%, carnosine 0.001-0.1%, water 0.001-0.1%;

and (3) phase F: 0.01-0.5% of PEG-40 hydrogenated castor oil and 0.001-0.1% of essence;

the amino acid compound comprises 4.2 percent of lysine, 1.5 percent of histidine, 3.8 percent of arginine, 8.1 percent of aspartic acid, 3.1 percent of threonine, 13.9 percent of serine, 12.9 percent of glutamic acid, 3.1 percent of proline, 25.1 percent of glycine, 4.5 percent of alanine, 3.1 percent of valine, 2.8 percent of isoleucine, 7.1 percent of leucine, 3.5 percent of tyrosine and 3.3 percent of phenylalanine according to the total weight of the amino acid compound.

2. The repair essence according to claim 1, wherein the water// hydroxyethyl urea in phase D is a mixture of two raw materials, wherein the mass ratio of water to hydroxyethyl urea is 8:9-9: 8; the water// butanediol// water temple laver polysaccharide in the phase D is a mixture of three raw materials, and according to the total weight, the water content is 69.5%, the butanediol content is 30%, and the water temple laver polysaccharide content is 0.5%.

3. The repair serum as claimed in claim 1, wherein the water// propylene glycol// pinocembrus tomentosa extract in phase E is a mixture of a plurality of raw materials, and has a water content of 48-52%, a propylene glycol content of 48-52%, a pinocembrus tomentosa extract content of 1-2.5%, and a sum of the weight of each component being 100%; the water// lactobacillus/soybean fermentation product extract// butanediol described in phase E is a mixture of various raw materials, wherein the mass ratio of water, lactobacillus/soybean fermentation product extract and butanediol is 78:10: 10.

4. The repair serum according to claim 1, wherein the fructo-oligosaccharide// glucose// fructose// sucrose in phase E is a mixture of a plurality of raw materials, and has a fructo-oligosaccharide content of 93%, a glucose content of 3%, a fructose content of 2%, and a sucrose content of 2% by total weight; the inulin// water// alpha-glucan oligosaccharide in phase E is a mixture of various raw materials, and the inulin content is 60-80%, the water content is 25%, the alpha-glucan oligosaccharide content is 1-14%, and the sum of the weight of the components is 100%, based on the total weight of the raw materials.

5. The preparation method of the repair essence according to claim 1, which mainly comprises the following steps:

1) heating the C-phase material to 70 ℃, and stirring and dissolving completely for later use;

2) uniformly stirring the F-phase material at normal temperature for later use;

3) adding the phase A materials into an emulsifying pot, heating to 90 ℃, and stirring to dissolve completely;

4) adding the phase B material into the solution obtained in the step 3), homogenizing for 7min, dispersing uniformly, and cooling;

5) cooling the solution obtained in the step 4) to 45 ℃, respectively adding the pretreated C, D, E, F-phase materials, stirring for 15min, and uniformly mixing.